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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Elf1_Elf2_Etv2_Elf4

Z-value: 11.43

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Transcription factors associated with Elf1_Elf2_Etv2_Elf4

Gene Symbol	Gene ID	Gene Info
Elf1 Ensembl NCBI MGI UniProt	ENSMUSG00000036461.9	E74-like factor 1
Elf2 Ensembl NCBI MGI UniProt	ENSMUSG00000037174.12	E74-like factor 2
Etv2 Ensembl NCBI MGI UniProt	ENSMUSG00000006311.8	ets variant 2
Elf4 Ensembl NCBI MGI UniProt	ENSMUSG00000031103.6	E74-like factor 4 (ets domain transcription factor)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_79535425_79535590	Elf1	19809	0.143772	0.76	1.5e-11	Click!
chr14_79521380_79521761	Elf1	5872	0.177440	0.73	1.7e-10	Click!
chr14_79537521_79537689	Elf1	21907	0.139494	0.70	2.5e-09	Click!
chr14_79515518_79515689	Elf1	71	0.969133	0.65	7.0e-08	Click!
chr14_79530269_79530420	Elf1	14646	0.153829	0.63	2.8e-07	Click!
chr3_51348932_51349101	Elf2	8353	0.109726	0.76	1.2e-11	Click!
chr3_51333354_51333527	Elf2	7121	0.118443	0.46	4.4e-04	Click!
chr3_51258160_51258311	Elf2	2006	0.222740	0.34	1.0e-02	Click!
chr3_51277221_51277642	Elf2	7	0.920802	0.32	1.7e-02	Click!
chr3_51340298_51341882	Elf2	427	0.737752	0.28	4.2e-02	Click!
chrX_48454344_48454508	Elf4	257	0.920396	0.86	6.6e-17	Click!
chrX_48439109_48439376	Elf4	14927	0.180462	0.81	3.8e-14	Click!
chrX_48433633_48433860	Elf4	20423	0.170340	0.79	5.0e-13	Click!
chrX_48453191_48453546	Elf4	801	0.635436	0.78	2.0e-12	Click!
chrX_48424704_48424876	Elf4	29379	0.150822	0.76	1.1e-11	Click!
chr7_30634710_30634935	Etv2	1030	0.240477	0.34	1.1e-02	Click!

Activity of the Elf1_Elf2_Etv2_Elf4 motif across conditions

Conditions sorted by the z-value of the Elf1_Elf2_Etv2_Elf4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_14351950_14353283	86.69	Il3ra	interleukin 3 receptor, alpha chain	2995	0.15
chr14_14354416_14355184	81.30	Il3ra	interleukin 3 receptor, alpha chain	5179	0.12
chrX_123721926_123722462	65.38	Rps12-ps23	ribosomal protein S12, pseudogene 23	13617	0.18
chrX_123500550_123501093	62.46	Rps12-ps22	ribosomal protein S12, pseudogene 22	13606	0.18
chrX_123271195_123271712	61.50	Rps12-ps21	ribosomal protein S12, pseudogene 22	13591	0.15
chr11_100938783_100940230	59.98	Stat3	signal transducer and activator of transcription 3	27	0.97
chr6_83032753_83034325	59.05	Dok1	docking protein 1	68	0.86
chr2_26139656_26141133	55.74	Tmem250-ps	transmembrane protein 250, pseudogene	127	0.93
chrX_123943434_123943951	54.98	Rps12-ps20	ribosomal protein S12, pseudogene 20	13582	0.23
chr2_129129245_129130482	52.50	Chchd5	coiled-coil-helix-coiled-coil-helix domain containing 5	13	0.96
chr16_95990397_95991380	51.99	Psmg1	proteasome (prosome, macropain) assembly chaperone 1	2	0.97
chr11_48855844_48857180	51.99	Gm16170	predicted gene 16170	3019	0.13
chr11_117781135_117781437	45.92	Tmc6	transmembrane channel-like gene family 6	342	0.64
chr3_84581929_84583242	45.30	Arfip1	ADP-ribosylation factor interacting protein 1	40	0.97
chr17_84181102_84182153	44.78	Gm36279	predicted gene, 36279	4129	0.18
chr3_65658208_65659857	44.52	Mir8120	microRNA 8120	256	0.89
chr9_109094576_109096217	44.43	Plxnb1	plexin B1	7	0.95
chr2_167492358_167493413	44.28	Spata2	spermatogenesis associated 2	2	0.76
chr9_50616581_50617570	44.06	Nkapd1	NKAP domain containing 1	189	0.55
chr8_70609185_70610414	44.02	Gm45546	predicted gene 45546	626	0.42
chr8_84197696_84198961	43.93	Gm26887	predicted gene, 26887	661	0.38
chr11_105125823_105126961	43.39	Mettl2	methyltransferase like 2	33	0.97
chr9_121277396_121277823	42.03	Gm34655	predicted gene, 34655	166	0.75
chr9_21615608_21616677	41.66	Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	27	0.95
chr6_91972143_91972459	39.99	Fgd5	FYVE, RhoGEF and PH domain containing 5	6577	0.15
chr5_137530580_137532081	38.79	Gnb2	guanine nucleotide binding protein (G protein), beta 2	33	0.9
chr9_108569718_108570862	38.17	Dalrd3	DALR anticodon binding domain containing 3	376	0.53
chr11_98941353_98942362	38.08	Rara	retinoic acid receptor, alpha	2145	0.18
chr11_79961869_79962916	37.93	Utp6	UTP6 small subunit processome component	2	0.97
chr7_127768560_127769629	37.84	Orai3	ORAI calcium release-activated calcium modulator 3	721	0.4
chr9_107982639_107983011	37.09	Uba7	ubiquitin-like modifier activating enzyme 7	200	0.49
chr2_32734991_32735206	35.56	Sh2d3c	SH2 domain containing 3C	183	0.51
chr2_26578486_26578697	35.43	Egfl7	EGF-like domain 7	1423	0.23
chr7_75611639_75612062	35.40	Akap13	A kinase (PRKA) anchor protein 13	10	0.98
chr9_61373312_61374646	35.27	Tle3	transducin-like enhancer of split 3	307	0.87
chr11_119912951_119914125	34.95	Chmp6	charged multivesicular body protein 6	97	0.95
chr19_45058030_45059049	34.60	Gm35867	predicted gene, 35867	302	0.83
chr6_124711627_124712957	34.52	Phb2	prohibitin 2	44	0.56
chr16_49798847_49799219	34.50	Gm15518	predicted gene 15518	163	0.95
chr8_126805357_126806196	34.47	A630001O12Rik	RIKEN cDNA A630001O12 gene	33457	0.16
chr8_33885663_33885895	34.37	Gm26978	predicted gene, 26978	32	0.97
chr8_20817574_20818579	34.26	Gm20946	predicted gene, 20946	10277	0.15
chr8_84979246_84980613	34.19	Junb	jun B proto-oncogene	1211	0.19
chr17_67512657_67513016	34.18	Gm36201	predicted gene, 36201	116496	0.06
chr11_120597854_120599056	34.00	Anapc11	anaphase promoting complex subunit 11	15	0.55
chr2_170147589_170148059	33.84	Zfp217	zinc finger protein 217	279	0.95
chr7_127091121_127091448	33.59	AI467606	expressed sequence AI467606	75	0.92
chr9_21846665_21847082	32.84	Dock6	dedicator of cytokinesis 6	5743	0.11
chr8_110217481_110218281	32.74	Cmtr2	cap methyltransferase 2	108	0.97
chr11_113806939_113807399	32.69	Sdk2	sidekick cell adhesion molecule 2	3254	0.26
chr13_60897419_60897689	32.65	Ctla2b	cytotoxic T lymphocyte-associated protein 2 beta	107	0.87
chr8_104095738_104095964	32.65	Cdh5	cadherin 5	5774	0.15
chr11_60114297_60115906	32.60	4930412M03Rik	RIKEN cDNA 4930412M03 gene	129	0.95
chr4_140701770_140702866	32.53	Rcc2	regulator of chromosome condensation 2	845	0.47
chr5_137349031_137350198	32.52	Ephb4	Eph receptor B4	495	0.62
chr6_115852875_115853903	32.45	Mbd4	methyl-CpG binding domain protein 4	18	0.55
chr6_29467899_29468607	32.40	Atp6v1f	ATPase, H+ transporting, lysosomal V1 subunit F	185	0.89
chr11_101551830_101552448	32.38	Nbr1	NBR1, autophagy cargo receptor	10	0.69
chr9_32400635_32401003	32.09	Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	6834	0.18
chr7_122132401_122133528	32.09	Palb2	partner and localizer of BRCA2	18	0.54
chr2_156312038_156312665	31.98	Cnbd2	cyclic nucleotide binding domain containing 2	52	0.83
chr2_181487275_181488108	31.95	Abhd16b	abhydrolase domain containing 16B	5515	0.11
chr7_44553417_44554082	31.89	Nr1h2	nuclear receptor subfamily 1, group H, member 2	41	0.92
chr17_14942812_14943939	31.84	1600012H06Rik	RIKEN cDNA 1600012H06 gene	104	0.64
chr1_64087943_64089121	31.80	Gm13748	predicted gene 13748	9878	0.19
chr2_84810833_84811663	31.78	Ube2l6	ubiquitin-conjugating enzyme E2L 6	5019	0.11
chrX_101428817_101430172	31.59	Nono	non-POU-domain-containing, octamer binding protein	61	0.96
chr6_34610528_34610706	31.50	Cald1	caldesmon 1	11997	0.19
chr16_17345263_17345421	31.18	Gm24927	predicted gene, 24927	3330	0.16
chr13_59823073_59823589	30.92	Gm34961	predicted gene, 34961	65	0.66
chr12_24633832_24634168	30.90	Gm6969	predicted pseudogene 6969	5010	0.17
chr12_101028530_101029714	30.84	Ccdc88c	coiled-coil domain containing 88C	66	0.95
chr7_112299432_112300079	30.73	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	16274	0.27
chr17_47909349_47909983	30.43	Gm15556	predicted gene 15556	12712	0.13
chr2_26902788_26903393	30.34	Surf6	surfeit gene 6	211	0.83
chr18_69782179_69782395	30.34	Tcf4	transcription factor 4	99907	0.07
chr11_59885300_59885570	30.24	Gm12714	predicted gene 12714	12939	0.11
chr11_108424530_108425250	29.89	Cep112	centrosomal protein 112	302	0.86
chr7_4792408_4793492	29.80	Rpl28	ribosomal protein L28	40	0.93
chr3_95893729_95894624	29.78	Aph1a	aph1 homolog A, gamma secretase subunit	121	0.9
chr4_137478244_137478657	29.77	Hspg2	perlecan (heparan sulfate proteoglycan 2)	9647	0.14
chr16_32130295_32130491	29.75	Nrros	negative regulator of reactive oxygen species	17488	0.1
chr2_165884402_165885933	29.56	Zmynd8	zinc finger, MYND-type containing 8	293	0.86
chr11_74896307_74898160	29.22	Sgsm2	small G protein signaling modulator 2	173	0.84
chr15_58140746_58142050	29.10	Wdyhv1	WDYHV motif containing 1	6	0.96
chr8_83332377_83333157	28.94	Elmod2	ELMO/CED-12 domain containing 2	281	0.87
chr6_47812781_47813882	28.86	Pdia4	protein disulfide isomerase associated 4	33	0.95
chr7_17058026_17058724	28.85	4833404L02Rik	RIKEN cDNA 4833404L02 gene	159	0.9
chrX_42067696_42069057	28.57	Xiap	X-linked inhibitor of apoptosis	22	0.98
chr5_135168094_135168944	28.54	Bcl7b	B cell CLL/lymphoma 7B	74	0.95
chr10_117792117_117793375	28.43	Nup107	nucleoporin 107	41	0.97
chr7_29453052_29453769	28.43	Sipa1l3	signal-induced proliferation-associated 1 like 3	52042	0.1
chr13_43480925_43481874	28.40	Ranbp9	RAN binding protein 9	117	0.95
chr1_86479174_86479713	28.12	Rpl30-ps6	ribosomal protein L30, pseudogene 6	5784	0.15
chr15_99332834_99333978	28.09	Fmnl3	formin-like 3	2321	0.16
chr14_21032131_21032511	28.07	Vcl	vinculin	10318	0.18
chr8_79638728_79640227	28.07	Otud4	OTU domain containing 4	141	0.96
chr5_115167520_115167731	28.02	Mlec	malectin	9446	0.1
chr4_127263680_127264160	28.01	Smim12	small integral membrane protein 12	20136	0.12
chr5_148361109_148361516	28.00	Slc7a1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	10234	0.23
chr2_152636359_152637068	27.93	Rem1	rad and gem related GTP binding protein 1	3746	0.1
chr5_137502130_137503030	27.90	Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)	62	0.52
chr17_35879583_35880431	27.88	Dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	182	0.82
chr8_121262895_121263071	27.78	5033426O07Rik	RIKEN cDNA 5033426O07 gene	59381	0.1
chr16_93603515_93604383	27.71	Setd4	SET domain containing 4	114	0.94
chr19_46455103_46455625	27.68	Sufu	SUFU negative regulator of hedgehog signaling	2542	0.23
chr5_75933655_75934023	27.63	Gm25374	predicted gene, 25374	24012	0.15
chr4_149445330_149446172	27.56	Rbp7	retinol binding protein 7, cellular	7673	0.11
chr15_99029765_99030391	27.43	Tuba1c	tubulin, alpha 1C	187	0.88
chr1_130740875_130741242	27.39	Gm28857	predicted gene 28857	269	0.74
chr11_120142404_120142866	27.34	Slc38a10	solute carrier family 38, member 10	149	0.92
chr5_115522010_115522417	27.32	Pxn	paxillin	1908	0.17
chr16_18876300_18877282	27.29	Mrpl40	mitochondrial ribosomal protein L40	71	0.73
chr11_49713043_49713524	27.13	Cnot6	CCR4-NOT transcription complex, subunit 6	560	0.67
chr1_80218340_80218558	27.11	Fam124b	family with sequence similarity 124, member B	24	0.97
chr15_73732102_73732772	27.09	Gm22106	predicted gene, 22106	3273	0.2
chr13_43231981_43232458	27.06	Tbc1d7	TBC1 domain family, member 7	60718	0.11
chr4_118489750_118490166	27.01	Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	103	0.94
chr7_100371458_100372465	26.95	Ppme1	protein phosphatase methylesterase 1	27	0.78
chr1_87626506_87626684	26.93	Inpp5d	inositol polyphosphate-5-phosphatase D	4921	0.19
chr11_61653094_61653390	26.80	Grap	GRB2-related adaptor protein	23	0.98
chr6_124919273_124920636	26.72	Ptms	parathymosin	149	0.88
chr18_61758967_61759164	26.72	1500015A07Rik	RIKEN cDNA 1500015A07 gene	24708	0.12
chr7_27490834_27491276	26.69	Sertad1	SERTA domain containing 1	3680	0.11
chr9_60687872_60688306	26.48	Lrrc49	leucine rich repeat containing 49	29	0.98
chr7_45017042_45018019	26.45	Rras	related RAS viral (r-ras) oncogene	431	0.52
chr2_85129465_85129890	26.45	Aplnr	apelin receptor	6548	0.13
chrX_53052410_53053563	26.33	Gm28730	predicted gene 28730	173	0.64
chr2_27540096_27540493	26.23	Gm13421	predicted gene 13421	132	0.76
chr17_56169887_56170252	26.21	Gm44397	predicted gene, 44397	2056	0.16
chr9_31253344_31253716	26.09	Gm7244	predicted gene 7244	21291	0.14
chr5_142425132_142425341	25.93	Foxk1	forkhead box K1	23736	0.17
chr5_43855901_43856053	25.88	Cd38	CD38 antigen	12576	0.1
chr11_55405684_55405936	25.84	Sparc	secreted acidic cysteine rich glycoprotein	3645	0.2
chr6_72552548_72553107	25.82	Capg	capping protein (actin filament), gelsolin-like	111	0.94
chr9_64045641_64045837	25.73	Gm25606	predicted gene, 25606	2757	0.18
chr8_46845214_46845396	25.73	Gm45481	predicted gene 45481	11393	0.18
chr9_63687465_63687734	25.72	Smad3	SMAD family member 3	21052	0.19
chr19_4059281_4059805	25.68	Gstp3	glutathione S-transferase pi 3	26	0.92
chr17_59012796_59013456	25.63	Nudt12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	142	0.96
chr6_5156500_5156801	25.59	Pon1	paraoxonase 1	37113	0.14
chr2_120128702_120129052	25.41	Ehd4	EH-domain containing 4	848	0.58
chr7_80763876_80764435	25.38	Gm44649	predicted gene 44649	12310	0.17
chr11_5505810_5506157	25.36	Gm11963	predicted gene 11963	7143	0.14
chr11_19924323_19926342	25.29	Spred2	sprouty-related EVH1 domain containing 2	890	0.71
chr8_126497512_126498658	25.28	Gm6091	predicted pseudogene 6091	21673	0.18
chr8_71371523_71372116	25.24	Ocel1	occludin/ELL domain containing 1	473	0.64
chr11_107529395_107529646	25.23	C330019F10Rik	RIKEN cDNA C330019F10 gene	2300	0.19
chr2_165954964_165955142	25.20	Gm11462	predicted gene 11462	4736	0.15
chr11_106382523_106382839	25.17	Icam2	intercellular adhesion molecule 2	100	0.95
chr16_4541512_4542439	25.09	Srl	sarcalumenin	159	0.93
chr2_75763399_75763611	25.07	Gm13657	predicted gene 13657	13683	0.14
chr1_73072233_73072629	24.90	1700027A15Rik	RIKEN cDNA 1700027A15 gene	47862	0.15
chr15_102350239_102351186	24.75	Aaas	achalasia, adrenocortical insufficiency, alacrimia	17	0.59
chr5_34168983_34169988	24.71	Haus3	HAUS augmin-like complex, subunit 3	18	0.5
chr6_38533231_38533979	24.70	Fmc1	formation of mitochondrial complex V assembly factor 1	103	0.96
chr6_136930773_136931096	24.63	Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	7102	0.13
chr17_80825502_80826283	24.61	C230072F16Rik	RIKEN cDNA C230072F16 gene	70901	0.1
chr7_90041544_90041927	24.59	Gm44861	predicted gene 44861	962	0.45
chr11_46065406_46066070	24.52	Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	9680	0.13
chr4_86898772_86899092	24.46	Acer2	alkaline ceramidase 2	24518	0.19
chr14_70074487_70075571	24.43	Egr3	early growth response 3	2174	0.25
chr2_30093353_30094532	24.39	Zdhhc12	zinc finger, DHHC domain containing 12	294	0.82
chr11_12036502_12038049	24.32	Grb10	growth factor receptor bound protein 10	126	0.97
chr15_98608664_98610204	24.29	Adcy6	adenylate cyclase 6	598	0.55
chr3_108562098_108562631	24.28	Tmem167b	transmembrane protein 167B	102	0.92
chr2_157367487_157367721	24.28	Manbal	mannosidase, beta A, lysosomal-like	10	0.97
chr17_23546226_23547548	24.26	6330415G19Rik	RIKEN cDNA 6330415G19 gene	3912	0.1
chr5_137596675_137597031	24.26	Mospd3	motile sperm domain containing 3	3838	0.08
chr6_88152237_88152433	24.25	Gm38708	predicted gene, 38708	38346	0.09
chr5_92745758_92746287	24.20	Gm20500	predicted gene 20500	9817	0.19
chr10_99268740_99269700	24.07	Gm34921	predicted gene, 34921	1226	0.27
chr7_25689001_25689947	24.07	Tgfb1	transforming growth factor, beta 1	547	0.58
chr2_92742025_92742423	24.07	Gm13816	predicted gene 13816	6	0.98
chr11_101248379_101248544	24.03	Ramp2	receptor (calcitonin) activity modifying protein 2	1368	0.19
chr7_29983352_29984044	23.98	Zfp568	zinc finger protein 568	257	0.84
chr12_13145384_13145901	23.98	Rpl21-ps2	ribosomal protein L21, pseudogene 2	4518	0.18
chr12_111007759_111007963	23.94	Gm48631	predicted gene, 48631	10541	0.11
chr4_142221224_142221954	23.93	Kazn	kazrin, periplakin interacting protein	11383	0.22
chr2_33870382_33870694	23.90	Mvb12b	multivesicular body subunit 12B	16307	0.21
chr10_61906420_61906571	23.82	Col13a1	collagen, type XIII, alpha 1	28103	0.17
chr3_88603769_88604137	23.76	Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	2013	0.16
chr8_94901065_94901679	23.76	Ccdc102a	coiled-coil domain containing 102A	16149	0.1
chr9_108338578_108339700	23.72	Gpx1	glutathione peroxidase 1	85	0.89
chr5_137103357_137103516	23.68	Trim56	tripartite motif-containing 56	12771	0.11
chr19_5388578_5389191	23.67	Sart1	squamous cell carcinoma antigen recognized by T cells 1	181	0.72
chr4_135312755_135313155	23.66	Gm12982	predicted gene 12982	4985	0.13
chr19_37435496_37435986	23.65	Hhex	hematopoietically expressed homeobox	931	0.35
chr5_115542702_115542988	23.62	Pxn	paxillin	69	0.94
chr5_139388247_139388459	23.51	Gpr146	G protein-coupled receptor 146	1432	0.28
chr11_61366020_61366293	23.50	Slc47a1	solute carrier family 47, member 1	504	0.72
chr8_128387224_128387560	23.46	Nrp1	neuropilin 1	27995	0.2
chr11_30648868_30649937	23.43	Acyp2	acylphosphatase 2, muscle type	185	0.95
chr10_127508848_127510720	23.39	Stac3	SH3 and cysteine rich domain 3	2559	0.15
chr6_48700249_48700426	23.32	Gimap6	GTPase, IMAP family member 6	5899	0.08
chr8_72295657_72296109	23.31	Gm10282	predicted pseudogene 10282	9377	0.11
chr7_80261042_80261722	23.27	Ngrn	neugrin, neurite outgrowth associated	162	0.9
chr3_101430437_101431033	23.24	Gm42538	predicted gene 42538	3799	0.2
chr10_7473576_7474027	23.23	Ulbp1	UL16 binding protein 1	163	0.96
chr3_84460630_84461321	23.23	Fhdc1	FH2 domain containing 1	7212	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf1_Elf2_Etv2_Elf4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
30.0	120.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
24.9	74.8	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
22.5	67.5	GO:0033668	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
22.3	44.6	GO:0060375	regulation of mast cell differentiation(GO:0060375)
21.6	43.3	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
19.3	57.9	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
18.3	54.8	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
18.2	54.6	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
17.6	52.8	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
17.5	52.5	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
17.5	17.5	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
17.3	17.3	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
17.2	68.9	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
16.0	48.1	GO:0050904	diapedesis(GO:0050904)
16.0	79.8	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
15.8	47.3	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
15.7	62.8	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
15.7	47.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
15.7	47.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
15.5	30.9	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
15.1	45.2	GO:0048769	sarcomerogenesis(GO:0048769)
15.0	44.9	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
14.6	43.7	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
14.3	43.0	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
14.2	42.5	GO:0002337	B-1a B cell differentiation(GO:0002337)
14.1	14.1	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
14.1	56.6	GO:0097460	ferrous iron import into cell(GO:0097460)
13.7	27.4	GO:0019371	cyclooxygenase pathway(GO:0019371)
13.6	40.9	GO:0034421	post-translational protein acetylation(GO:0034421)
13.6	40.7	GO:0061470	T follicular helper cell differentiation(GO:0061470)
13.2	39.7	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
13.1	52.4	GO:0031581	hemidesmosome assembly(GO:0031581)
13.1	52.3	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
13.0	51.9	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
13.0	51.8	GO:0097039	protein linear polyubiquitination(GO:0097039)
12.8	64.1	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
12.7	12.7	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
12.6	50.4	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
12.5	37.6	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
12.5	37.6	GO:0061043	regulation of vascular wound healing(GO:0061043)
12.5	37.4	GO:0002432	granuloma formation(GO:0002432)
12.5	12.5	GO:0070384	Harderian gland development(GO:0070384)
12.5	62.4	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
12.5	24.9	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
12.4	49.6	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
12.3	24.7	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
12.2	36.6	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
12.2	48.7	GO:0001887	selenium compound metabolic process(GO:0001887)
12.1	24.2	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
12.1	36.2	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
11.9	35.7	GO:0003166	bundle of His development(GO:0003166)
11.5	34.4	GO:0006982	response to lipid hydroperoxide(GO:0006982)
11.4	45.8	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
11.3	33.8	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
11.2	66.9	GO:0061620	glycolytic process through glucose-6-phosphate(GO:0061620)
11.1	55.7	GO:0075525	viral translational termination-reinitiation(GO:0075525)
11.1	33.3	GO:0034499	late endosome to Golgi transport(GO:0034499)
11.1	33.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
11.1	88.5	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
11.0	55.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
10.9	43.7	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
10.9	32.8	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
10.9	65.5	GO:0002441	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
10.9	32.6	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
10.9	32.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
10.8	32.5	GO:0060137	maternal process involved in parturition(GO:0060137)
10.8	32.5	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
10.7	42.8	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
10.7	32.1	GO:0009804	coumarin metabolic process(GO:0009804)
10.6	53.1	GO:0070836	caveola assembly(GO:0070836)
10.6	21.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
10.5	42.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
10.5	31.5	GO:0000087	mitotic M phase(GO:0000087)
10.4	41.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
10.4	31.2	GO:2000297	negative regulation of synapse maturation(GO:2000297)
10.4	20.8	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
10.4	31.2	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
10.4	20.7	GO:1904059	regulation of locomotor rhythm(GO:1904059)
10.4	10.4	GO:0060319	regulation of primitive erythrocyte differentiation(GO:0010725) primitive erythrocyte differentiation(GO:0060319)
10.4	20.7	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
10.3	41.0	GO:0007296	vitellogenesis(GO:0007296)
10.1	50.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
10.1	30.3	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
10.1	30.3	GO:1902075	cellular response to salt(GO:1902075)
10.1	20.2	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
10.1	10.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
10.0	30.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
10.0	30.1	GO:1903334	positive regulation of protein folding(GO:1903334)
10.0	10.0	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
10.0	30.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
10.0	10.0	GO:0035973	aggrephagy(GO:0035973)
9.9	19.7	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
9.8	19.6	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
9.8	29.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
9.8	29.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
9.8	9.8	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
9.7	136.3	GO:0006907	pinocytosis(GO:0006907)
9.7	29.1	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
9.6	28.9	GO:0007525	somatic muscle development(GO:0007525)
9.6	38.5	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
9.6	28.9	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
9.6	28.9	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
9.6	28.7	GO:0006172	ADP biosynthetic process(GO:0006172)
9.5	9.5	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
9.5	47.6	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
9.5	28.5	GO:0002554	serotonin secretion by platelet(GO:0002554)
9.5	19.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
9.5	28.4	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
9.5	9.5	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
9.4	18.8	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
9.4	37.6	GO:0072675	osteoclast fusion(GO:0072675)
9.4	18.8	GO:0060931	sinoatrial node cell development(GO:0060931)
9.3	28.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
9.3	46.5	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
9.3	37.1	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
9.3	46.3	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
9.2	46.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
9.2	82.9	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
9.2	55.0	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
9.2	45.8	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
9.2	9.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
9.1	18.3	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683)
9.1	45.6	GO:0015722	canalicular bile acid transport(GO:0015722)
9.1	36.3	GO:0051541	elastin metabolic process(GO:0051541)
9.1	27.2	GO:0071316	cellular response to nicotine(GO:0071316)
9.1	72.5	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
9.0	9.0	GO:1903679	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
9.0	90.4	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
9.0	81.3	GO:0031507	heterochromatin assembly(GO:0031507)
8.9	8.9	GO:0043096	purine nucleobase salvage(GO:0043096)
8.9	107.0	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
8.9	26.7	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
8.9	17.8	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
8.9	35.6	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
8.9	17.7	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
8.9	53.2	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
8.8	44.2	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
8.8	35.3	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
8.8	53.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
8.8	44.0	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
8.8	26.4	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
8.8	17.6	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
8.8	35.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
8.8	26.3	GO:1904424	regulation of GTP binding(GO:1904424)
8.7	43.7	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
8.6	8.6	GO:0006680	glucosylceramide catabolic process(GO:0006680)
8.6	25.7	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
8.5	34.2	GO:0031033	myosin filament organization(GO:0031033)
8.5	25.6	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
8.5	110.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
8.5	25.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
8.4	8.4	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
8.4	8.4	GO:0034729	histone H3-K79 methylation(GO:0034729)
8.4	25.3	GO:0006481	C-terminal protein methylation(GO:0006481)
8.4	33.6	GO:0006116	NADH oxidation(GO:0006116)
8.4	33.5	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
8.3	25.0	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
8.3	25.0	GO:1902570	protein localization to nucleolus(GO:1902570)
8.3	33.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
8.3	16.5	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
8.3	33.1	GO:0006742	NADP catabolic process(GO:0006742)
8.3	57.8	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
8.2	24.7	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
8.2	16.5	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
8.2	74.0	GO:0097062	dendritic spine maintenance(GO:0097062)
8.2	32.9	GO:0072697	protein localization to cell cortex(GO:0072697)
8.2	57.3	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
8.2	24.5	GO:0008228	opsonization(GO:0008228)
8.1	24.4	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
8.1	24.3	GO:1990791	dorsal root ganglion development(GO:1990791)
8.1	8.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
8.1	16.2	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
8.1	32.4	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
8.1	32.3	GO:0003096	renal sodium ion transport(GO:0003096)
8.1	64.4	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
8.0	64.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
8.0	24.0	GO:0061687	detoxification of inorganic compound(GO:0061687)
8.0	8.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
8.0	31.9	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
8.0	8.0	GO:0010992	ubiquitin homeostasis(GO:0010992)
8.0	23.9	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
7.9	39.7	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
7.9	7.9	GO:0046618	drug export(GO:0046618)
7.9	31.6	GO:0034115	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
7.9	31.5	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
7.9	55.0	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
7.8	15.7	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
7.8	46.7	GO:0000212	meiotic spindle organization(GO:0000212)
7.8	31.0	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
7.7	15.5	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
7.7	84.9	GO:0007035	vacuolar acidification(GO:0007035)
7.7	77.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
7.7	30.9	GO:0070831	basement membrane assembly(GO:0070831)
7.7	15.4	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
7.7	7.7	GO:0070627	ferrous iron import(GO:0070627)
7.7	15.4	GO:0048320	axial mesoderm formation(GO:0048320)
7.7	15.3	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
7.7	15.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
7.7	38.3	GO:0007220	Notch receptor processing(GO:0007220)
7.7	15.3	GO:0032439	endosome localization(GO:0032439)
7.6	15.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
7.6	45.6	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
7.6	30.3	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
7.6	22.7	GO:0032971	regulation of muscle filament sliding(GO:0032971)
7.6	22.7	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
7.6	45.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
7.5	22.6	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
7.5	15.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
7.5	90.2	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
7.5	7.5	GO:1901800	positive regulation of proteasomal protein catabolic process(GO:1901800)
7.5	7.5	GO:0006549	isoleucine metabolic process(GO:0006549)
7.5	52.4	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
7.4	37.1	GO:0033194	response to hydroperoxide(GO:0033194)
7.4	110.8	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
7.4	88.6	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
7.3	14.7	GO:2000823	regulation of androgen receptor activity(GO:2000823)
7.3	14.6	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
7.3	14.6	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
7.3	29.2	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
7.3	36.6	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
7.3	58.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
7.3	14.5	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
7.2	115.5	GO:0006783	heme biosynthetic process(GO:0006783)
7.2	14.4	GO:0032782	bile acid secretion(GO:0032782)
7.2	115.4	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
7.2	7.2	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
7.2	14.3	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
7.1	50.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
7.1	14.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
7.1	14.2	GO:0035483	gastric emptying(GO:0035483)
7.1	21.3	GO:0018992	germ-line sex determination(GO:0018992)
7.1	35.5	GO:0019934	cGMP-mediated signaling(GO:0019934)
7.1	14.1	GO:0032803	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
7.0	70.3	GO:0035518	histone H2A monoubiquitination(GO:0035518)
7.0	28.1	GO:0018343	protein farnesylation(GO:0018343)
7.0	21.0	GO:0097167	circadian regulation of translation(GO:0097167)
7.0	14.0	GO:0016095	polyprenol catabolic process(GO:0016095)
7.0	97.7	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
7.0	13.9	GO:0015886	heme transport(GO:0015886)
6.9	13.9	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
6.9	13.9	GO:0019676	ammonia assimilation cycle(GO:0019676)
6.9	20.8	GO:0090224	regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
6.9	27.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
6.9	13.8	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
6.9	20.7	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
6.9	48.2	GO:0020027	hemoglobin metabolic process(GO:0020027)
6.9	6.9	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
6.9	54.9	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
6.9	68.6	GO:0043129	surfactant homeostasis(GO:0043129)
6.9	20.6	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
6.9	20.6	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
6.8	34.2	GO:0043652	engulfment of apoptotic cell(GO:0043652)
6.8	6.8	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
6.8	88.8	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
6.8	6.8	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
6.8	20.5	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
6.8	20.5	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
6.8	27.2	GO:1900153	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
6.8	13.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
6.8	6.8	GO:0006691	leukotriene metabolic process(GO:0006691)
6.8	13.5	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
6.8	27.0	GO:0031049	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
6.8	33.8	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
6.7	13.5	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
6.7	6.7	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
6.7	13.4	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
6.7	40.2	GO:0006004	fucose metabolic process(GO:0006004)
6.7	20.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
6.7	20.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
6.7	26.7	GO:0046060	dATP metabolic process(GO:0046060)
6.7	73.4	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
6.7	53.3	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
6.7	20.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
6.7	20.0	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
6.6	13.3	GO:1902966	protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
6.6	26.5	GO:0051031	tRNA transport(GO:0051031)
6.6	59.4	GO:0071361	cellular response to ethanol(GO:0071361)
6.6	6.6	GO:0019042	viral latency(GO:0019042)
6.6	13.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
6.6	26.3	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
6.6	85.4	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
6.6	6.6	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
6.6	13.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
6.5	26.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
6.5	32.7	GO:0001842	neural fold formation(GO:0001842)
6.5	13.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
6.5	13.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
6.5	26.0	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
6.5	6.5	GO:0085020	protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
6.4	57.9	GO:0033004	negative regulation of mast cell activation(GO:0033004)
6.4	12.8	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
6.4	6.4	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
6.4	25.6	GO:0043328	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
6.4	19.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
6.4	25.5	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
6.4	12.7	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
6.4	6.4	GO:0046185	aldehyde catabolic process(GO:0046185)
6.3	19.0	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
6.3	19.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
6.3	25.3	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235)
6.3	19.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
6.3	18.9	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
6.3	12.6	GO:0006701	progesterone biosynthetic process(GO:0006701)
6.3	18.9	GO:0015793	glycerol transport(GO:0015793)
6.3	18.9	GO:0070828	heterochromatin organization(GO:0070828)
6.3	44.0	GO:0048194	Golgi vesicle budding(GO:0048194)
6.3	31.4	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
6.3	6.3	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
6.3	31.3	GO:0032482	Rab protein signal transduction(GO:0032482)
6.3	6.3	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
6.3	43.8	GO:0030953	astral microtubule organization(GO:0030953)
6.2	24.9	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
6.2	31.1	GO:1903671	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
6.2	12.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
6.2	55.7	GO:0007097	nuclear migration(GO:0007097)
6.2	80.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
6.2	30.8	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
6.2	6.2	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
6.2	6.2	GO:0035995	detection of muscle stretch(GO:0035995)
6.2	6.2	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
6.2	30.8	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
6.1	24.6	GO:0070837	dehydroascorbic acid transport(GO:0070837)
6.1	6.1	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
6.1	12.2	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
6.1	18.3	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
6.1	6.1	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
6.1	12.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
6.1	18.2	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
6.0	42.3	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
6.0	24.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
6.0	6.0	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
6.0	18.0	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
6.0	60.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
6.0	29.9	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
6.0	11.9	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
6.0	29.8	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
6.0	41.7	GO:0035372	protein localization to microtubule(GO:0035372)
6.0	6.0	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
5.9	17.8	GO:0046104	thymidine metabolic process(GO:0046104)
5.9	95.0	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
5.9	23.7	GO:0015871	choline transport(GO:0015871)
5.9	23.6	GO:0010713	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966)
5.9	70.7	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
5.9	5.9	GO:0003164	His-Purkinje system development(GO:0003164)
5.9	17.6	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
5.9	70.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
5.9	23.4	GO:0030218	erythrocyte differentiation(GO:0030218)
5.8	23.4	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
5.8	23.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
5.8	23.3	GO:0036302	atrioventricular canal development(GO:0036302)
5.8	69.8	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
5.8	52.3	GO:0046697	decidualization(GO:0046697)
5.8	11.6	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
5.8	23.2	GO:0009414	response to water deprivation(GO:0009414)
5.8	11.6	GO:0019401	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
5.8	5.8	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
5.8	23.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
5.8	5.8	GO:0070922	small RNA loading onto RISC(GO:0070922)
5.8	17.4	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
5.8	17.3	GO:0031947	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947)
5.8	28.9	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
5.8	5.8	GO:0032621	interleukin-18 production(GO:0032621)
5.8	17.3	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
5.8	11.5	GO:1903525	regulation of membrane tubulation(GO:1903525)
5.8	11.5	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
5.7	5.7	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
5.7	34.2	GO:0016540	protein autoprocessing(GO:0016540)
5.7	17.1	GO:0006741	NADP biosynthetic process(GO:0006741)
5.7	17.1	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
5.7	17.1	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
5.7	17.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
5.7	28.4	GO:0070475	rRNA base methylation(GO:0070475)
5.7	28.4	GO:0045820	negative regulation of glycolytic process(GO:0045820)
5.7	11.4	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
5.7	11.4	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
5.7	56.7	GO:0002115	store-operated calcium entry(GO:0002115)
5.7	34.0	GO:0036010	protein localization to endosome(GO:0036010)
5.6	16.8	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
5.6	16.8	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
5.6	44.8	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
5.6	55.9	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
5.6	22.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
5.6	50.2	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
5.5	22.2	GO:0060283	negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
5.5	49.9	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
5.5	16.6	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
5.5	22.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
5.5	5.5	GO:1903599	positive regulation of mitophagy(GO:1903599)
5.5	27.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
5.5	16.5	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
5.5	11.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
5.5	21.9	GO:0030049	muscle filament sliding(GO:0030049)
5.5	16.4	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
5.5	5.5	GO:0060674	placenta blood vessel development(GO:0060674)
5.5	16.4	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
5.5	49.1	GO:0032486	Rap protein signal transduction(GO:0032486)
5.4	32.6	GO:0050916	sensory perception of sweet taste(GO:0050916)
5.4	21.7	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
5.4	59.2	GO:0043248	proteasome assembly(GO:0043248)
5.4	37.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
5.4	5.4	GO:1901857	positive regulation of cellular respiration(GO:1901857)
5.3	16.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
5.3	5.3	GO:0043330	response to exogenous dsRNA(GO:0043330)
5.3	5.3	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
5.3	111.9	GO:0006301	postreplication repair(GO:0006301)
5.3	26.6	GO:0001866	NK T cell proliferation(GO:0001866)
5.3	26.6	GO:0006572	tyrosine catabolic process(GO:0006572)
5.3	26.6	GO:0010815	bradykinin catabolic process(GO:0010815)
5.3	53.1	GO:0031269	pseudopodium assembly(GO:0031269)
5.3	5.3	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
5.3	15.8	GO:1903147	negative regulation of mitophagy(GO:1903147)
5.3	5.3	GO:0070163	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
5.3	15.8	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
5.3	26.3	GO:0045792	negative regulation of cell size(GO:0045792)
5.2	5.2	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
5.2	31.4	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
5.2	10.4	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
5.2	10.4	GO:0034114	regulation of heterotypic cell-cell adhesion(GO:0034114) positive regulation of heterotypic cell-cell adhesion(GO:0034116)
5.2	5.2	GO:0033129	positive regulation of histone phosphorylation(GO:0033129)
5.2	26.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
5.2	5.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
5.2	25.9	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
5.2	25.9	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
5.2	10.3	GO:0070889	platelet alpha granule organization(GO:0070889)
5.2	25.8	GO:0018101	protein citrullination(GO:0018101)
5.2	10.3	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
5.2	10.3	GO:0035754	B cell chemotaxis(GO:0035754)
5.1	5.1	GO:0043622	cortical microtubule organization(GO:0043622)
5.1	46.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
5.1	15.4	GO:0034720	histone H3-K4 demethylation(GO:0034720)
5.1	61.4	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
5.1	40.9	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
5.1	15.3	GO:0033483	gas homeostasis(GO:0033483)
5.1	91.8	GO:0001574	ganglioside biosynthetic process(GO:0001574)
5.1	5.1	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
5.1	66.3	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
5.1	20.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
5.1	5.1	GO:0060281	regulation of oocyte development(GO:0060281)
5.1	15.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
5.0	15.1	GO:0006393	termination of mitochondrial transcription(GO:0006393)
5.0	25.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
5.0	5.0	GO:0006382	adenosine to inosine editing(GO:0006382)
5.0	5.0	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
5.0	14.9	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
5.0	64.7	GO:0060337	type I interferon signaling pathway(GO:0060337)
5.0	10.0	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
5.0	5.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
5.0	19.9	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
5.0	9.9	GO:0090365	regulation of mRNA modification(GO:0090365)
5.0	24.8	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
5.0	5.0	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
5.0	24.8	GO:0031053	primary miRNA processing(GO:0031053)
5.0	9.9	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
4.9	19.8	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
4.9	19.8	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
4.9	14.8	GO:0051006	positive regulation of lipoprotein lipase activity(GO:0051006)
4.9	4.9	GO:0061724	lipophagy(GO:0061724)
4.9	14.8	GO:0042938	dipeptide transport(GO:0042938)
4.9	4.9	GO:0019805	quinolinate biosynthetic process(GO:0019805)
4.9	19.7	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
4.9	9.8	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
4.9	19.6	GO:0090527	actin filament reorganization(GO:0090527)
4.9	34.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
4.9	19.6	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
4.9	68.6	GO:0006098	pentose-phosphate shunt(GO:0006098)
4.9	14.7	GO:0061635	regulation of protein complex stability(GO:0061635)
4.9	4.9	GO:0042525	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
4.9	14.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
4.9	49.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
4.9	19.6	GO:0003091	renal water homeostasis(GO:0003091)
4.9	14.6	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
4.9	19.5	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
4.9	34.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
4.9	14.6	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
4.8	9.7	GO:0002576	platelet degranulation(GO:0002576)
4.8	14.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
4.8	4.8	GO:0051660	establishment of centrosome localization(GO:0051660)
4.8	38.6	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
4.8	9.6	GO:0016553	base conversion or substitution editing(GO:0016553)
4.8	28.9	GO:0050930	induction of positive chemotaxis(GO:0050930)
4.8	14.4	GO:0051775	response to redox state(GO:0051775)
4.8	72.0	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
4.8	24.0	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
4.8	24.0	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
4.8	19.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
4.8	38.3	GO:0046085	adenosine metabolic process(GO:0046085)
4.8	4.8	GO:0035740	CD8-positive, alpha-beta T cell proliferation(GO:0035740)
4.8	4.8	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
4.8	28.6	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
4.8	14.3	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
4.8	4.8	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
4.7	9.5	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
4.7	14.2	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
4.7	19.0	GO:0031061	negative regulation of histone methylation(GO:0031061)
4.7	14.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
4.7	18.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
4.7	18.9	GO:0031584	activation of phospholipase D activity(GO:0031584)
4.7	14.2	GO:1903061	positive regulation of protein lipidation(GO:1903061)
4.7	23.6	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
4.7	4.7	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
4.7	14.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
4.7	14.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
4.7	14.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
4.7	28.2	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
4.7	14.1	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990)
4.7	4.7	GO:0060155	platelet dense granule organization(GO:0060155)
4.6	18.6	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
4.6	18.6	GO:0050872	white fat cell differentiation(GO:0050872)
4.6	13.9	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
4.6	13.9	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
4.6	55.3	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
4.6	64.5	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
4.6	18.3	GO:0034340	response to type I interferon(GO:0034340)
4.6	50.2	GO:0071801	regulation of podosome assembly(GO:0071801)
4.6	9.1	GO:0044793	negative regulation by host of viral process(GO:0044793)
4.6	4.6	GO:0010643	cell communication by chemical coupling(GO:0010643)
4.6	13.7	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
4.6	36.4	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
4.5	9.1	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
4.5	13.6	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
4.5	27.2	GO:0043173	nucleotide salvage(GO:0043173)
4.5	9.0	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
4.5	4.5	GO:0034443	negative regulation of lipoprotein oxidation(GO:0034443)
4.5	18.1	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
4.5	13.5	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029) negative regulation of neutrophil apoptotic process(GO:0033030)
4.5	9.0	GO:0032596	protein transport into membrane raft(GO:0032596)
4.5	9.0	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
4.5	13.5	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
4.5	4.5	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
4.5	35.9	GO:0030212	hyaluronan metabolic process(GO:0030212)
4.5	9.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
4.5	31.3	GO:0050779	RNA destabilization(GO:0050779)
4.5	13.4	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
4.5	4.5	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
4.5	8.9	GO:1901678	iron coordination entity transport(GO:1901678)
4.5	4.5	GO:0044090	positive regulation of vacuole organization(GO:0044090)
4.4	4.4	GO:0097242	beta-amyloid clearance(GO:0097242)
4.4	8.9	GO:0035511	oxidative DNA demethylation(GO:0035511)
4.4	13.3	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
4.4	4.4	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
4.4	13.3	GO:0023021	termination of signal transduction(GO:0023021)
4.4	26.6	GO:0032464	regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
4.4	8.9	GO:0035788	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) regulation of metanephric mesenchymal cell migration(GO:2000589)
4.4	13.3	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
4.4	26.6	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
4.4	13.3	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
4.4	26.5	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
4.4	8.8	GO:0090335	regulation of brown fat cell differentiation(GO:0090335)
4.4	30.9	GO:0034058	endosomal vesicle fusion(GO:0034058)
4.4	17.6	GO:0015809	arginine transport(GO:0015809)
4.4	13.2	GO:0045006	DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
4.4	4.4	GO:0035902	response to immobilization stress(GO:0035902)
4.4	13.2	GO:0016556	mRNA modification(GO:0016556)
4.4	8.8	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
4.4	13.2	GO:0001555	oocyte growth(GO:0001555)
4.4	8.8	GO:0090343	positive regulation of cell aging(GO:0090343)
4.4	13.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
4.4	8.7	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
4.4	26.2	GO:0006561	proline biosynthetic process(GO:0006561)
4.4	13.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.4	8.7	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
4.4	52.2	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
4.3	17.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
4.3	17.4	GO:0007290	spermatid nucleus elongation(GO:0007290)
4.3	13.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
4.3	8.7	GO:0035927	RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
4.3	13.0	GO:0006449	regulation of translational termination(GO:0006449)
4.3	8.6	GO:0052472	modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
4.3	4.3	GO:0034501	protein localization to kinetochore(GO:0034501)
4.3	12.9	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
4.3	4.3	GO:0019344	cysteine biosynthetic process(GO:0019344)
4.3	4.3	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
4.3	8.6	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
4.3	4.3	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
4.3	21.3	GO:0097421	liver regeneration(GO:0097421)
4.3	12.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
4.3	12.8	GO:0060352	cell adhesion molecule production(GO:0060352)
4.2	8.5	GO:0006573	valine metabolic process(GO:0006573)
4.2	12.7	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
4.2	12.7	GO:0000966	RNA 5'-end processing(GO:0000966)
4.2	8.5	GO:1990705	cholangiocyte proliferation(GO:1990705)
4.2	42.3	GO:0001731	formation of translation preinitiation complex(GO:0001731)
4.2	4.2	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
4.2	12.6	GO:0002315	marginal zone B cell differentiation(GO:0002315)
4.2	4.2	GO:0031860	telomeric 3' overhang formation(GO:0031860)
4.2	4.2	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
4.2	21.0	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
4.2	46.2	GO:0009437	carnitine metabolic process(GO:0009437)
4.2	25.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
4.2	8.4	GO:0070257	positive regulation of mucus secretion(GO:0070257)
4.2	16.8	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
4.2	37.7	GO:0006855	drug transmembrane transport(GO:0006855)
4.2	46.1	GO:0035767	endothelial cell chemotaxis(GO:0035767)
4.2	25.1	GO:0051639	actin filament network formation(GO:0051639)
4.2	8.4	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
4.2	4.2	GO:0043084	penile erection(GO:0043084)
4.2	4.2	GO:0051593	response to folic acid(GO:0051593)
4.2	8.3	GO:0006551	leucine metabolic process(GO:0006551)
4.2	8.3	GO:0002159	desmosome assembly(GO:0002159)
4.2	4.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
4.1	24.9	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
4.1	12.4	GO:0035935	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
4.1	4.1	GO:1903059	regulation of protein lipidation(GO:1903059)
4.1	24.8	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
4.1	4.1	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
4.1	28.9	GO:0006110	regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811)
4.1	20.6	GO:0010668	ectodermal cell differentiation(GO:0010668)
4.1	65.8	GO:0016239	positive regulation of macroautophagy(GO:0016239)
4.1	24.6	GO:0042255	ribosome assembly(GO:0042255)
4.1	4.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
4.1	126.5	GO:0070527	platelet aggregation(GO:0070527)
4.1	81.5	GO:0014823	response to activity(GO:0014823)
4.1	48.8	GO:0070266	necroptotic process(GO:0070266)
4.0	20.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
4.0	48.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
4.0	8.1	GO:0070268	cornification(GO:0070268)
4.0	4.0	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
4.0	4.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
4.0	4.0	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
4.0	12.0	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
4.0	16.0	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
4.0	80.0	GO:0046825	regulation of protein export from nucleus(GO:0046825)
4.0	12.0	GO:0051014	actin filament severing(GO:0051014)
4.0	36.0	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
4.0	23.9	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
4.0	19.9	GO:0042866	pyruvate biosynthetic process(GO:0042866)
4.0	31.8	GO:0006013	mannose metabolic process(GO:0006013)
4.0	7.9	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
4.0	4.0	GO:0006522	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
4.0	11.9	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
3.9	3.9	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
3.9	55.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
3.9	19.7	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
3.9	7.8	GO:0006344	maintenance of chromatin silencing(GO:0006344)
3.9	27.4	GO:0051382	kinetochore assembly(GO:0051382)
3.9	27.4	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
3.9	7.8	GO:0042989	sequestering of actin monomers(GO:0042989)
3.9	19.5	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
3.9	11.7	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
3.9	19.5	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
3.9	3.9	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
3.9	35.0	GO:0018904	ether metabolic process(GO:0018904)
3.9	11.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
3.9	19.4	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
3.9	7.8	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
3.9	11.6	GO:0048539	bone marrow development(GO:0048539)
3.9	3.9	GO:1900368	regulation of RNA interference(GO:1900368)
3.9	11.6	GO:0060613	fat pad development(GO:0060613)
3.9	7.7	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
3.9	11.6	GO:0009838	abscission(GO:0009838)
3.9	15.4	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
3.9	3.9	GO:0055089	fatty acid homeostasis(GO:0055089)
3.8	11.5	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
3.8	3.8	GO:1903055	positive regulation of extracellular matrix organization(GO:1903055)
3.8	11.5	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
3.8	11.5	GO:0032594	protein transport within lipid bilayer(GO:0032594)
3.8	7.7	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
3.8	34.5	GO:0045724	positive regulation of cilium assembly(GO:0045724)
3.8	7.7	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
3.8	26.8	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
3.8	11.5	GO:0060903	positive regulation of meiosis I(GO:0060903)
3.8	15.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
3.8	7.6	GO:0035405	histone-threonine phosphorylation(GO:0035405)
3.8	22.8	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
3.8	3.8	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
3.8	15.1	GO:0002227	innate immune response in mucosa(GO:0002227)
3.8	3.8	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
3.8	30.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
3.8	3.8	GO:0032075	positive regulation of nuclease activity(GO:0032075)
3.7	11.2	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
3.7	3.7	GO:0051964	negative regulation of synapse assembly(GO:0051964)
3.7	11.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
3.7	18.6	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
3.7	14.9	GO:0048227	plasma membrane to endosome transport(GO:0048227)
3.7	77.8	GO:0018345	protein palmitoylation(GO:0018345)
3.7	11.1	GO:0040031	snRNA modification(GO:0040031)
3.7	11.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
3.7	29.5	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
3.7	11.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
3.7	14.7	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
3.7	33.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
3.7	18.4	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
3.7	7.3	GO:0030223	neutrophil differentiation(GO:0030223)
3.7	3.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
3.7	62.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
3.7	21.9	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
3.6	14.6	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
3.6	58.4	GO:1903146	regulation of mitophagy(GO:1903146)
3.6	25.5	GO:0030575	nuclear body organization(GO:0030575)
3.6	10.9	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
3.6	7.3	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
3.6	10.9	GO:0048541	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
3.6	21.7	GO:0018065	protein-cofactor linkage(GO:0018065)
3.6	10.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
3.6	7.2	GO:0072592	oxygen metabolic process(GO:0072592)
3.6	28.7	GO:0051601	exocyst localization(GO:0051601)
3.6	3.6	GO:0050917	sensory perception of umami taste(GO:0050917)
3.6	3.6	GO:0072718	response to cisplatin(GO:0072718)
3.6	21.4	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
3.6	7.1	GO:0048388	endosomal lumen acidification(GO:0048388)
3.6	3.6	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
3.6	14.2	GO:0098535	de novo centriole assembly(GO:0098535)
3.6	3.6	GO:0046292	formaldehyde metabolic process(GO:0046292)
3.6	32.0	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
3.5	14.2	GO:0035988	chondrocyte proliferation(GO:0035988)
3.5	21.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
3.5	14.2	GO:0021873	forebrain neuroblast division(GO:0021873)
3.5	3.5	GO:2000468	regulation of peroxidase activity(GO:2000468)
3.5	28.3	GO:2000785	regulation of autophagosome assembly(GO:2000785)
3.5	38.9	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
3.5	10.6	GO:0046208	spermine catabolic process(GO:0046208)
3.5	3.5	GO:1902914	regulation of protein polyubiquitination(GO:1902914) positive regulation of protein polyubiquitination(GO:1902916)
3.5	10.6	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
3.5	49.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
3.5	7.0	GO:0048102	autophagic cell death(GO:0048102)
3.5	14.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
3.5	21.1	GO:0006477	protein sulfation(GO:0006477)
3.5	3.5	GO:0070318	G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) positive regulation of G0 to G1 transition(GO:0070318)
3.5	10.5	GO:0046325	negative regulation of glucose import(GO:0046325)
3.5	52.5	GO:0050819	negative regulation of coagulation(GO:0050819)
3.5	3.5	GO:1903012	positive regulation of bone development(GO:1903012)
3.5	7.0	GO:0048318	axial mesoderm development(GO:0048318)
3.5	14.0	GO:0010692	regulation of alkaline phosphatase activity(GO:0010692)
3.5	14.0	GO:0033572	transferrin transport(GO:0033572)
3.5	7.0	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
3.5	10.5	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
3.5	7.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.5	13.9	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
3.5	10.4	GO:0018206	peptidyl-methionine modification(GO:0018206)
3.5	24.4	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
3.5	7.0	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
3.5	38.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
3.5	10.4	GO:0016126	sterol biosynthetic process(GO:0016126)
3.5	10.4	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
3.5	17.4	GO:0033003	regulation of mast cell activation(GO:0033003)
3.5	3.5	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
3.5	3.5	GO:0080009	mRNA methylation(GO:0080009)
3.5	20.8	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
3.5	6.9	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
3.4	17.2	GO:0042448	progesterone metabolic process(GO:0042448)
3.4	13.8	GO:0007100	mitotic centrosome separation(GO:0007100)
3.4	3.4	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
3.4	17.2	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
3.4	3.4	GO:0045974	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
3.4	20.5	GO:0048535	lymph node development(GO:0048535)
3.4	10.3	GO:0060988	lipid tube assembly(GO:0060988)
3.4	27.3	GO:0035994	response to muscle stretch(GO:0035994)
3.4	13.6	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.4	20.3	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
3.4	47.3	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
3.4	60.8	GO:0006513	protein monoubiquitination(GO:0006513)
3.4	27.0	GO:0034063	stress granule assembly(GO:0034063)
3.4	3.4	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
3.4	13.4	GO:0018202	peptidyl-histidine modification(GO:0018202)
3.4	20.1	GO:0008298	intracellular mRNA localization(GO:0008298)
3.4	3.4	GO:0052173	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
3.3	10.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
3.3	16.7	GO:0016266	O-glycan processing(GO:0016266)
3.3	6.7	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
3.3	6.7	GO:0045900	negative regulation of translational elongation(GO:0045900)
3.3	10.0	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
3.3	23.3	GO:0001771	immunological synapse formation(GO:0001771)
3.3	6.6	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
3.3	13.3	GO:0006776	vitamin A metabolic process(GO:0006776)
3.3	33.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
3.3	6.6	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
3.3	3.3	GO:0060430	lung saccule development(GO:0060430)
3.3	6.5	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
3.3	6.5	GO:0043302	positive regulation of leukocyte degranulation(GO:0043302)
3.3	13.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
3.3	19.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
3.3	9.8	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
3.3	26.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
3.3	35.8	GO:1901739	regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
3.3	9.8	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
3.3	13.0	GO:0006083	acetate metabolic process(GO:0006083)
3.3	3.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
3.3	9.8	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
3.3	16.3	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
3.2	9.7	GO:0043504	mitochondrial DNA repair(GO:0043504)
3.2	22.7	GO:0015697	quaternary ammonium group transport(GO:0015697)
3.2	16.2	GO:0006527	arginine catabolic process(GO:0006527)
3.2	12.9	GO:0043984	histone H4-K16 acetylation(GO:0043984)
3.2	9.7	GO:0046951	ketone body biosynthetic process(GO:0046951)
3.2	12.9	GO:0051292	nuclear pore complex assembly(GO:0051292)
3.2	16.1	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
3.2	25.8	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
3.2	16.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
3.2	3.2	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
3.2	6.4	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
3.2	57.9	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
3.2	22.5	GO:0033047	regulation of mitotic sister chromatid segregation(GO:0033047)
3.2	3.2	GO:1901679	nucleotide transmembrane transport(GO:1901679)
3.2	9.6	GO:0006543	glutamine catabolic process(GO:0006543)
3.2	12.8	GO:0019673	GDP-mannose metabolic process(GO:0019673)
3.2	9.6	GO:0006056	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
3.2	9.6	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
3.2	16.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
3.2	12.8	GO:0009446	putrescine biosynthetic process(GO:0009446)
3.2	19.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
3.2	25.6	GO:0044126	regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
3.2	12.8	GO:0071318	cellular response to ATP(GO:0071318)
3.2	9.6	GO:0009597	detection of virus(GO:0009597)
3.2	12.7	GO:0008063	Toll signaling pathway(GO:0008063)
3.2	3.2	GO:0097237	cellular response to toxic substance(GO:0097237)
3.2	3.2	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
3.2	6.4	GO:0006833	water transport(GO:0006833)
3.2	15.9	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
3.2	6.3	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
3.2	44.3	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
3.2	3.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
3.2	22.1	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
3.1	15.7	GO:0006525	arginine metabolic process(GO:0006525)
3.1	6.3	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
3.1	3.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
3.1	6.3	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
3.1	9.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
3.1	15.6	GO:0009109	coenzyme catabolic process(GO:0009109)
3.1	3.1	GO:0001969	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
3.1	3.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
3.1	6.2	GO:0007060	male meiosis chromosome segregation(GO:0007060)
3.1	3.1	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
3.1	9.4	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.1	15.6	GO:0051026	chiasma assembly(GO:0051026)
3.1	28.0	GO:0045922	negative regulation of fatty acid metabolic process(GO:0045922)
3.1	3.1	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
3.1	9.3	GO:0018916	nitrobenzene metabolic process(GO:0018916)
3.1	24.9	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
3.1	9.3	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
3.1	9.3	GO:0050915	sensory perception of sour taste(GO:0050915)
3.1	34.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
3.1	12.4	GO:0070305	response to cGMP(GO:0070305)
3.1	6.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
3.1	15.5	GO:0009992	cellular water homeostasis(GO:0009992)
3.1	24.7	GO:0060712	spongiotrophoblast layer development(GO:0060712)
3.1	12.4	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
3.1	123.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
3.1	15.4	GO:0016574	histone ubiquitination(GO:0016574)
3.1	15.4	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
3.1	3.1	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)
3.1	18.4	GO:0002467	germinal center formation(GO:0002467)
3.1	3.1	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
3.1	3.1	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
3.1	6.1	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
3.1	3.1	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
3.0	12.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
3.0	3.0	GO:1901421	positive regulation of response to alcohol(GO:1901421)
3.0	6.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
3.0	9.1	GO:0042732	D-xylose metabolic process(GO:0042732)
3.0	6.1	GO:0035812	renal sodium excretion(GO:0035812) regulation of renal sodium excretion(GO:0035813)
3.0	3.0	GO:0036093	germ cell proliferation(GO:0036093)
3.0	3.0	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
3.0	48.5	GO:0017144	drug metabolic process(GO:0017144)
3.0	36.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
3.0	12.1	GO:0051596	methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
3.0	42.2	GO:0006879	cellular iron ion homeostasis(GO:0006879)
3.0	12.1	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
3.0	21.1	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
3.0	18.1	GO:0046051	UTP metabolic process(GO:0046051)
3.0	3.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
3.0	36.1	GO:0051492	regulation of stress fiber assembly(GO:0051492)
3.0	3.0	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
3.0	3.0	GO:0010958	regulation of amino acid import(GO:0010958)
3.0	9.0	GO:0051013	microtubule severing(GO:0051013)
3.0	6.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
3.0	18.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
3.0	3.0	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
3.0	12.0	GO:2000756	regulation of peptidyl-lysine acetylation(GO:2000756)
3.0	3.0	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
3.0	11.9	GO:0048680	positive regulation of axon regeneration(GO:0048680)
3.0	8.9	GO:0048739	cardiac muscle fiber development(GO:0048739)
3.0	11.8	GO:0033623	regulation of integrin activation(GO:0033623)
3.0	14.8	GO:0051084	'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
3.0	5.9	GO:0070459	prolactin secretion(GO:0070459)
2.9	8.8	GO:0032494	response to peptidoglycan(GO:0032494)
2.9	17.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.9	29.5	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566)
2.9	17.7	GO:0001840	neural plate development(GO:0001840)
2.9	2.9	GO:0032347	regulation of aldosterone biosynthetic process(GO:0032347)
2.9	58.6	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
2.9	5.9	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
2.9	8.8	GO:0035855	megakaryocyte development(GO:0035855)
2.9	5.8	GO:0071895	odontoblast differentiation(GO:0071895)
2.9	14.6	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
2.9	32.1	GO:0031648	protein destabilization(GO:0031648)
2.9	2.9	GO:0007127	meiosis I(GO:0007127)
2.9	17.5	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.9	8.7	GO:1901186	positive regulation of ERBB signaling pathway(GO:1901186)
2.9	5.8	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
2.9	8.7	GO:0080154	regulation of fertilization(GO:0080154)
2.9	5.8	GO:0030730	sequestering of triglyceride(GO:0030730)
2.9	2.9	GO:0071107	response to parathyroid hormone(GO:0071107)
2.9	2.9	GO:0003352	regulation of cilium movement(GO:0003352)
2.9	5.8	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
2.9	23.2	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
2.9	2.9	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
2.9	8.7	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838)
2.9	43.4	GO:0032648	regulation of interferon-beta production(GO:0032648)
2.9	5.8	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
2.9	5.8	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
2.9	11.5	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
2.9	14.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
2.9	5.8	GO:1901475	pyruvate transmembrane transport(GO:1901475)
2.9	2.9	GO:1902969	mitotic DNA replication(GO:1902969)
2.9	2.9	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
2.9	2.9	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
2.9	57.4	GO:0043297	apical junction assembly(GO:0043297)
2.9	11.5	GO:0042420	dopamine catabolic process(GO:0042420)
2.9	2.9	GO:0045022	early endosome to late endosome transport(GO:0045022)
2.8	5.7	GO:0021564	vagus nerve development(GO:0021564)
2.8	17.0	GO:0033327	Leydig cell differentiation(GO:0033327)
2.8	28.3	GO:0032007	negative regulation of TOR signaling(GO:0032007)
2.8	70.9	GO:0043966	histone H3 acetylation(GO:0043966)
2.8	8.5	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
2.8	8.5	GO:0045176	apical protein localization(GO:0045176)
2.8	5.6	GO:0006706	steroid catabolic process(GO:0006706)
2.8	25.2	GO:0070269	pyroptosis(GO:0070269)
2.8	33.6	GO:0006144	purine nucleobase metabolic process(GO:0006144)
2.8	2.8	GO:0046596	regulation of viral entry into host cell(GO:0046596)
2.8	5.6	GO:0001757	somite specification(GO:0001757)
2.8	28.0	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
2.8	25.2	GO:0007603	phototransduction, visible light(GO:0007603)
2.8	11.2	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
2.8	41.9	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
2.8	14.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
2.8	8.4	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
2.8	5.6	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
2.8	2.8	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
2.8	5.6	GO:0051383	kinetochore organization(GO:0051383)
2.8	2.8	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
2.8	8.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
2.8	13.8	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
2.7	5.5	GO:0033762	response to glucagon(GO:0033762)
2.7	5.5	GO:0003383	apical constriction(GO:0003383)
2.7	16.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
2.7	49.2	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
2.7	2.7	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
2.7	2.7	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
2.7	10.8	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
2.7	27.0	GO:2000758	positive regulation of peptidyl-lysine acetylation(GO:2000758)
2.7	5.4	GO:0009299	mRNA transcription(GO:0009299)
2.7	21.5	GO:0006968	cellular defense response(GO:0006968)
2.7	69.8	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
2.7	13.4	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
2.7	10.7	GO:0007000	nucleolus organization(GO:0007000)
2.7	5.3	GO:1903795	regulation of inorganic anion transmembrane transport(GO:1903795)
2.7	5.3	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
2.7	5.3	GO:1901723	negative regulation of cell proliferation involved in kidney development(GO:1901723)
2.7	2.7	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
2.7	5.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
2.7	2.7	GO:0060631	regulation of meiosis I(GO:0060631)
2.7	5.3	GO:0071800	podosome assembly(GO:0071800)
2.7	37.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
2.7	5.3	GO:0090400	stress-induced premature senescence(GO:0090400)
2.6	5.3	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
2.6	29.1	GO:0071353	cellular response to interleukin-4(GO:0071353)
2.6	26.4	GO:0097194	execution phase of apoptosis(GO:0097194)
2.6	5.3	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
2.6	5.3	GO:1905208	negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
2.6	10.5	GO:1902093	positive regulation of sperm motility(GO:1902093)
2.6	13.1	GO:0060294	cilium movement involved in cell motility(GO:0060294)
2.6	7.9	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
2.6	10.5	GO:0015868	purine ribonucleotide transport(GO:0015868)
2.6	57.6	GO:0007029	endoplasmic reticulum organization(GO:0007029)
2.6	7.8	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
2.6	15.6	GO:0032060	bleb assembly(GO:0032060)
2.6	2.6	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
2.6	10.4	GO:2000482	regulation of interleukin-8 secretion(GO:2000482)
2.6	7.8	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
2.6	5.2	GO:0070254	mucus secretion(GO:0070254)
2.6	2.6	GO:0006667	sphinganine metabolic process(GO:0006667)
2.6	118.7	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
2.6	7.7	GO:0071985	multivesicular body sorting pathway(GO:0071985)
2.6	2.6	GO:0009750	response to fructose(GO:0009750) cellular response to fructose stimulus(GO:0071332)
2.6	12.9	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
2.6	7.7	GO:0014043	negative regulation of neuron maturation(GO:0014043)
2.6	7.7	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
2.6	12.8	GO:0040016	embryonic cleavage(GO:0040016)
2.6	10.3	GO:0015705	iodide transport(GO:0015705)
2.6	5.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
2.6	17.9	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
2.6	15.3	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
2.6	15.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
2.5	38.2	GO:0000186	activation of MAPKK activity(GO:0000186)
2.5	7.6	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
2.5	50.9	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
2.5	5.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
2.5	5.1	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
2.5	5.0	GO:0001556	oocyte maturation(GO:0001556)
2.5	7.5	GO:0018119	peptidyl-cysteine S-nitrosylation(GO:0018119)
2.5	7.5	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
2.5	10.0	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
2.5	2.5	GO:0002314	germinal center B cell differentiation(GO:0002314)
2.5	34.9	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
2.5	10.0	GO:0030321	transepithelial chloride transport(GO:0030321)
2.5	12.5	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
2.5	22.4	GO:1902750	negative regulation of cell cycle G2/M phase transition(GO:1902750)
2.5	24.9	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
2.5	2.5	GO:0070875	positive regulation of glycogen metabolic process(GO:0070875)
2.5	7.4	GO:0019321	pentose metabolic process(GO:0019321)
2.5	76.5	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
2.5	2.5	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
2.5	7.4	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
2.5	12.3	GO:0008343	adult feeding behavior(GO:0008343)
2.5	4.9	GO:0009139	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
2.4	7.3	GO:0001880	Mullerian duct regression(GO:0001880)
2.4	17.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.4	39.0	GO:0060323	head morphogenesis(GO:0060323)
2.4	4.9	GO:0006577	amino-acid betaine metabolic process(GO:0006577)
2.4	46.2	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
2.4	17.0	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
2.4	41.2	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
2.4	7.3	GO:0061042	vascular wound healing(GO:0061042)
2.4	4.8	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
2.4	2.4	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
2.4	14.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
2.4	4.8	GO:0002215	defense response to nematode(GO:0002215)
2.4	26.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
2.4	2.4	GO:0006532	aspartate biosynthetic process(GO:0006532)
2.4	24.0	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
2.4	26.4	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
2.4	7.2	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.4	14.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.4	31.1	GO:0010508	positive regulation of autophagy(GO:0010508)
2.4	4.8	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
2.4	9.5	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
2.4	16.7	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
2.4	28.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
2.4	4.7	GO:2001198	regulation of dendritic cell differentiation(GO:2001198) negative regulation of dendritic cell differentiation(GO:2001199)
2.4	9.5	GO:0015671	oxygen transport(GO:0015671)
2.4	7.1	GO:0032677	regulation of interleukin-8 production(GO:0032677)
2.4	16.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
2.4	33.0	GO:0050873	brown fat cell differentiation(GO:0050873)
2.4	30.6	GO:0010761	fibroblast migration(GO:0010761)
2.3	54.0	GO:0045445	myoblast differentiation(GO:0045445)
2.3	110.3	GO:0051028	mRNA transport(GO:0051028)
2.3	18.8	GO:0002026	regulation of the force of heart contraction(GO:0002026)
2.3	7.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
2.3	7.0	GO:0015889	cobalamin transport(GO:0015889)
2.3	37.3	GO:0006611	protein export from nucleus(GO:0006611)
2.3	9.3	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
2.3	7.0	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
2.3	9.3	GO:0015732	prostaglandin transport(GO:0015732)
2.3	4.6	GO:0010459	negative regulation of heart rate(GO:0010459)
2.3	13.9	GO:0007257	activation of JUN kinase activity(GO:0007257)
2.3	7.0	GO:0015744	succinate transport(GO:0015744)
2.3	2.3	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
2.3	2.3	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
2.3	9.3	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
2.3	2.3	GO:0035455	response to interferon-alpha(GO:0035455)
2.3	2.3	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
2.3	23.0	GO:0001782	B cell homeostasis(GO:0001782)
2.3	2.3	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
2.3	20.7	GO:0006026	aminoglycan catabolic process(GO:0006026)
2.3	4.6	GO:0035810	positive regulation of urine volume(GO:0035810)
2.3	45.7	GO:0060976	coronary vasculature development(GO:0060976)
2.3	4.6	GO:0002281	macrophage activation involved in immune response(GO:0002281)
2.3	4.6	GO:0046487	glyoxylate metabolic process(GO:0046487)
2.3	4.5	GO:0048143	astrocyte activation(GO:0048143)
2.3	2.3	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
2.3	2.3	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
2.3	6.8	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
2.3	43.0	GO:0007569	cell aging(GO:0007569)
2.3	2.3	GO:0065001	specification of axis polarity(GO:0065001)
2.3	6.8	GO:0006824	cobalt ion transport(GO:0006824)
2.2	11.2	GO:0002591	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
2.2	11.2	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
2.2	15.7	GO:0046686	response to cadmium ion(GO:0046686)
2.2	6.7	GO:0007144	female meiosis I(GO:0007144)
2.2	4.5	GO:0043383	negative T cell selection(GO:0043383)
2.2	15.5	GO:0018095	protein polyglutamylation(GO:0018095)
2.2	8.9	GO:0001893	maternal placenta development(GO:0001893)
2.2	2.2	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
2.2	4.4	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
2.2	22.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
2.2	15.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
2.2	8.8	GO:0009110	vitamin biosynthetic process(GO:0009110) water-soluble vitamin biosynthetic process(GO:0042364)
2.2	8.8	GO:0051784	negative regulation of nuclear division(GO:0051784)
2.2	4.4	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
2.2	13.1	GO:0050658	nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
2.2	8.8	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
2.2	4.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
2.2	4.4	GO:1904406	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
2.2	39.1	GO:0006695	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
2.2	2.2	GO:1903751	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
2.2	2.2	GO:0070303	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
2.2	15.1	GO:0000305	response to oxygen radical(GO:0000305)
2.2	19.4	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
2.2	2.2	GO:0044838	cell quiescence(GO:0044838)
2.2	2.2	GO:0032570	response to progesterone(GO:0032570)
2.2	6.5	GO:0006739	NADP metabolic process(GO:0006739)
2.1	8.6	GO:0032096	negative regulation of response to food(GO:0032096)
2.1	30.1	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
2.1	44.8	GO:1905037	autophagosome organization(GO:1905037)
2.1	21.3	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.1	4.3	GO:0016139	glycoside catabolic process(GO:0016139)
2.1	21.3	GO:0035456	response to interferon-beta(GO:0035456)
2.1	2.1	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
2.1	17.0	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
2.1	12.8	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
2.1	2.1	GO:0097531	mast cell migration(GO:0097531)
2.1	4.2	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
2.1	12.6	GO:0007076	mitotic chromosome condensation(GO:0007076)
2.1	4.2	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
2.1	29.4	GO:0030032	lamellipodium assembly(GO:0030032)
2.1	37.8	GO:0051310	metaphase plate congression(GO:0051310)
2.1	6.3	GO:0023035	CD40 signaling pathway(GO:0023035)
2.1	8.4	GO:0032801	receptor catabolic process(GO:0032801)
2.1	6.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
2.1	4.2	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
2.1	6.3	GO:0042501	serine phosphorylation of STAT3 protein(GO:0033136) serine phosphorylation of STAT protein(GO:0042501)
2.1	22.9	GO:0006743	ubiquinone metabolic process(GO:0006743)
2.1	10.4	GO:0034227	tRNA thio-modification(GO:0034227)
2.1	2.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
2.1	6.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
2.1	18.7	GO:0042572	retinol metabolic process(GO:0042572)
2.1	2.1	GO:0061462	protein localization to lysosome(GO:0061462)
2.1	2.1	GO:0009650	UV protection(GO:0009650)
2.1	14.4	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.1	10.3	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
2.1	10.3	GO:0000012	single strand break repair(GO:0000012)
2.1	4.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
2.0	4.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
2.0	4.1	GO:0060068	vagina development(GO:0060068)
2.0	10.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
2.0	2.0	GO:0060242	contact inhibition(GO:0060242)
2.0	6.1	GO:0046174	polyol catabolic process(GO:0046174)
2.0	8.2	GO:0045059	positive thymic T cell selection(GO:0045059)
2.0	20.4	GO:0001706	endoderm formation(GO:0001706)
2.0	2.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823)
2.0	6.1	GO:0090201	negative regulation of release of cytochrome c from mitochondria(GO:0090201)
2.0	4.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
2.0	2.0	GO:0072053	renal inner medulla development(GO:0072053)
2.0	14.2	GO:0070306	lens fiber cell differentiation(GO:0070306)
2.0	10.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
2.0	4.0	GO:0005984	disaccharide metabolic process(GO:0005984)
2.0	6.1	GO:0050832	defense response to fungus(GO:0050832)
2.0	12.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
2.0	2.0	GO:0061009	common bile duct development(GO:0061009)
2.0	4.0	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
2.0	4.0	GO:0060056	mammary gland involution(GO:0060056)
2.0	12.1	GO:0006308	DNA catabolic process(GO:0006308)
2.0	4.0	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
2.0	4.0	GO:0032965	regulation of collagen biosynthetic process(GO:0032965) positive regulation of collagen biosynthetic process(GO:0032967)
2.0	8.0	GO:0021670	lateral ventricle development(GO:0021670)
2.0	33.8	GO:0016573	histone acetylation(GO:0016573)
2.0	4.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
2.0	2.0	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
2.0	9.9	GO:0015825	L-serine transport(GO:0015825)
2.0	9.9	GO:1902018	negative regulation of cilium assembly(GO:1902018)
2.0	2.0	GO:0061046	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
2.0	2.0	GO:0002447	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
2.0	5.9	GO:0052548	regulation of endopeptidase activity(GO:0052548)
2.0	9.8	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
2.0	9.8	GO:0045576	mast cell activation(GO:0045576)
2.0	9.8	GO:0060065	uterus development(GO:0060065)
2.0	9.8	GO:0034198	cellular response to amino acid starvation(GO:0034198)
2.0	7.8	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
2.0	3.9	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
2.0	3.9	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
1.9	5.8	GO:0016572	histone phosphorylation(GO:0016572)
1.9	9.7	GO:0006353	DNA-templated transcription, termination(GO:0006353)
1.9	46.6	GO:0001892	embryonic placenta development(GO:0001892)
1.9	1.9	GO:0060324	face development(GO:0060324)
1.9	34.7	GO:0008333	endosome to lysosome transport(GO:0008333)
1.9	9.6	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.9	7.7	GO:0016559	peroxisome fission(GO:0016559)
1.9	1.9	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
1.9	1.9	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.9	9.6	GO:0009235	cobalamin metabolic process(GO:0009235)
1.9	1.9	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
1.9	3.8	GO:0000729	DNA double-strand break processing(GO:0000729)
1.9	3.8	GO:0021569	rhombomere 3 development(GO:0021569)
1.9	9.5	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
1.9	5.7	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
1.9	7.6	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
1.9	26.7	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
1.9	5.7	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.9	1.9	GO:0010884	positive regulation of lipid storage(GO:0010884)
1.9	1.9	GO:0030318	melanocyte differentiation(GO:0030318)
1.9	1.9	GO:0010818	T cell chemotaxis(GO:0010818)
1.9	13.3	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
1.9	17.1	GO:0006828	manganese ion transport(GO:0006828)
1.9	5.7	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
1.9	5.7	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
1.9	1.9	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
1.9	15.0	GO:0033561	regulation of water loss via skin(GO:0033561)
1.9	7.5	GO:0045582	positive regulation of T cell differentiation(GO:0045582)
1.9	3.7	GO:0006499	N-terminal protein myristoylation(GO:0006499)
1.9	3.7	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
1.9	58.0	GO:0002323	natural killer cell activation involved in immune response(GO:0002323)
1.9	3.7	GO:0048850	hypophysis morphogenesis(GO:0048850)
1.9	37.4	GO:0042073	intraciliary transport(GO:0042073)
1.9	26.2	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
1.9	7.5	GO:0072520	seminiferous tubule development(GO:0072520)
1.9	1.9	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
1.9	5.6	GO:0000101	sulfur amino acid transport(GO:0000101)
1.9	1.9	GO:0090594	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
1.8	1.8	GO:0014829	vascular smooth muscle contraction(GO:0014829)
1.8	3.7	GO:0033260	nuclear DNA replication(GO:0033260)
1.8	1.8	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) positive regulation of sodium:proton antiporter activity(GO:0032417)
1.8	9.2	GO:0048251	elastic fiber assembly(GO:0048251)
1.8	5.5	GO:0018094	protein polyglycylation(GO:0018094)
1.8	12.9	GO:0016926	protein desumoylation(GO:0016926)
1.8	1.8	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
1.8	1.8	GO:0060965	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.8	3.6	GO:1903273	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
1.8	1.8	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661)
1.8	9.1	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
1.8	23.5	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
1.8	1.8	GO:0015747	urate transport(GO:0015747)
1.8	3.6	GO:0071218	response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
1.8	9.0	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
1.8	10.8	GO:0045947	negative regulation of translational initiation(GO:0045947)
1.8	9.0	GO:0072501	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.8	1.8	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.8	5.3	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
1.8	14.2	GO:0070208	protein heterotrimerization(GO:0070208)
1.8	10.6	GO:0030261	chromosome condensation(GO:0030261)
1.8	7.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.8	49.5	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
1.8	8.8	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
1.8	1.8	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.8	1.8	GO:0045830	positive regulation of isotype switching(GO:0045830)
1.8	1.8	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
1.8	1.8	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
1.8	1.8	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
1.7	24.4	GO:0042832	defense response to protozoan(GO:0042832)
1.7	3.5	GO:0044788	modulation by host of viral process(GO:0044788)
1.7	5.2	GO:0016137	glycoside metabolic process(GO:0016137)
1.7	6.9	GO:0009313	oligosaccharide catabolic process(GO:0009313)
1.7	6.9	GO:0060326	cell chemotaxis(GO:0060326)
1.7	3.5	GO:0032897	negative regulation of viral transcription(GO:0032897)
1.7	1.7	GO:0002036	regulation of L-glutamate transport(GO:0002036)
1.7	13.8	GO:0048741	skeletal muscle fiber development(GO:0048741)
1.7	25.8	GO:0016180	snRNA processing(GO:0016180)
1.7	6.9	GO:0071897	DNA biosynthetic process(GO:0071897)
1.7	25.7	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
1.7	5.1	GO:0010039	response to iron ion(GO:0010039)
1.7	6.8	GO:0015909	long-chain fatty acid transport(GO:0015909)
1.7	13.6	GO:0048753	pigment granule organization(GO:0048753)
1.7	3.4	GO:0051799	negative regulation of hair follicle development(GO:0051799)
1.7	11.9	GO:0051973	positive regulation of telomerase activity(GO:0051973)
1.7	6.8	GO:0007032	endosome organization(GO:0007032)
1.7	5.1	GO:0006278	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
1.7	11.9	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
1.7	1.7	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.7	3.4	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
1.7	5.1	GO:0014041	regulation of neuron maturation(GO:0014041)
1.7	6.7	GO:0021800	cerebral cortex tangential migration(GO:0021800)
1.7	10.1	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
1.7	1.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.7	6.6	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
1.7	3.3	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
1.7	6.6	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
1.7	14.9	GO:0030888	regulation of B cell proliferation(GO:0030888)
1.7	3.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
1.6	1.6	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
1.6	4.9	GO:2000253	positive regulation of feeding behavior(GO:2000253)
1.6	4.9	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
1.6	6.6	GO:0046040	IMP metabolic process(GO:0046040)
1.6	9.8	GO:0030168	platelet activation(GO:0030168)
1.6	32.7	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
1.6	9.8	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
1.6	13.0	GO:0010507	negative regulation of autophagy(GO:0010507)
1.6	14.7	GO:0051875	pigment granule localization(GO:0051875)
1.6	3.3	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.6	16.2	GO:0044243	multicellular organism catabolic process(GO:0044243)
1.6	3.2	GO:0030916	otic vesicle formation(GO:0030916)
1.6	4.9	GO:1902047	polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
1.6	13.0	GO:0008053	mitochondrial fusion(GO:0008053)
1.6	3.2	GO:0006545	glycine biosynthetic process(GO:0006545)
1.6	6.5	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.6	77.7	GO:0007051	spindle organization(GO:0007051)
1.6	4.8	GO:0034204	lipid translocation(GO:0034204)
1.6	3.2	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
1.6	8.1	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814)
1.6	9.7	GO:0030225	macrophage differentiation(GO:0030225)
1.6	1.6	GO:0098754	detoxification(GO:0098754)
1.6	4.8	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
1.6	1.6	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
1.6	1.6	GO:0045346	regulation of MHC class II biosynthetic process(GO:0045346)
1.6	4.8	GO:0036233	glycine import(GO:0036233)
1.6	6.4	GO:0002347	response to tumor cell(GO:0002347)
1.6	3.2	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
1.6	1.6	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
1.6	23.7	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
1.6	7.9	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
1.6	28.3	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
1.6	4.7	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
1.6	11.0	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
1.6	1.6	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.6	1.6	GO:0014904	myotube cell development(GO:0014904)
1.6	3.1	GO:0002183	cytoplasmic translational initiation(GO:0002183)
1.6	15.7	GO:0036158	outer dynein arm assembly(GO:0036158)
1.6	3.1	GO:0045136	development of secondary sexual characteristics(GO:0045136)
1.6	14.0	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.6	1.6	GO:0001692	histamine metabolic process(GO:0001692)
1.5	3.1	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
1.5	7.7	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.5	3.1	GO:0019372	lipoxygenase pathway(GO:0019372)
1.5	3.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.5	1.5	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
1.5	6.1	GO:0046889	positive regulation of lipid biosynthetic process(GO:0046889)
1.5	13.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
1.5	1.5	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
1.5	6.1	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
1.5	4.5	GO:0002385	organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
1.5	3.0	GO:0071236	cellular response to antibiotic(GO:0071236)
1.5	6.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
1.5	10.5	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
1.5	3.0	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
1.5	6.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
1.5	9.0	GO:0042574	retinal metabolic process(GO:0042574)
1.5	1.5	GO:0098840	protein transport along microtubule(GO:0098840)
1.5	4.5	GO:0035457	cellular response to interferon-alpha(GO:0035457)
1.5	10.4	GO:0006569	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
1.5	4.5	GO:0060017	parathyroid gland development(GO:0060017)
1.5	1.5	GO:0034101	erythrocyte homeostasis(GO:0034101)
1.5	14.8	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
1.5	1.5	GO:0010446	response to alkaline pH(GO:0010446)
1.5	1.5	GO:0032692	negative regulation of interleukin-1 production(GO:0032692)
1.5	1.5	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
1.5	1.5	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
1.5	1.5	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
1.5	7.3	GO:0048246	macrophage chemotaxis(GO:0048246)
1.5	2.9	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
1.5	7.3	GO:1901571	icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
1.4	7.2	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
1.4	1.4	GO:0014827	intestine smooth muscle contraction(GO:0014827)
1.4	8.7	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
1.4	20.2	GO:0003009	skeletal muscle contraction(GO:0003009)
1.4	1.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
1.4	2.9	GO:0042991	transcription factor import into nucleus(GO:0042991)
1.4	1.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.4	4.3	GO:0015670	carbon dioxide transport(GO:0015670)
1.4	1.4	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
1.4	2.8	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
1.4	1.4	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
1.4	29.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
1.4	2.8	GO:0033275	actin-myosin filament sliding(GO:0033275)
1.4	1.4	GO:0006689	ganglioside catabolic process(GO:0006689)
1.4	2.8	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.4	18.0	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.4	1.4	GO:0021612	facial nerve structural organization(GO:0021612)
1.4	1.4	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
1.4	6.9	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
1.4	2.7	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
1.4	1.4	GO:0001562	response to protozoan(GO:0001562)
1.4	10.9	GO:0070166	enamel mineralization(GO:0070166)
1.4	8.1	GO:0007041	lysosomal transport(GO:0007041)
1.4	1.4	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
1.3	41.8	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
1.3	5.4	GO:1903364	positive regulation of cellular protein catabolic process(GO:1903364)
1.3	21.5	GO:0006491	N-glycan processing(GO:0006491)
1.3	22.8	GO:0006334	nucleosome assembly(GO:0006334)
1.3	13.4	GO:0032355	response to estradiol(GO:0032355)
1.3	10.7	GO:0045454	cell redox homeostasis(GO:0045454)
1.3	2.7	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
1.3	5.3	GO:0006857	oligopeptide transport(GO:0006857)
1.3	2.7	GO:0030210	heparin biosynthetic process(GO:0030210)
1.3	4.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
1.3	2.7	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.3	1.3	GO:2000035	regulation of stem cell division(GO:2000035)
1.3	25.1	GO:0006730	one-carbon metabolic process(GO:0006730)
1.3	2.6	GO:0043255	regulation of carbohydrate biosynthetic process(GO:0043255)
1.3	9.2	GO:0006476	protein deacetylation(GO:0006476)
1.3	2.6	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
1.3	1.3	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196)
1.3	2.6	GO:0006534	cysteine metabolic process(GO:0006534)
1.3	10.4	GO:0008209	androgen metabolic process(GO:0008209)
1.3	35.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
1.3	3.9	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
1.3	3.9	GO:0046599	regulation of centriole replication(GO:0046599)
1.3	14.2	GO:0051591	response to cAMP(GO:0051591)
1.3	2.6	GO:2000316	regulation of T-helper 17 type immune response(GO:2000316)
1.3	1.3	GO:0048478	replication fork protection(GO:0048478)
1.3	2.6	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3	5.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
1.3	9.0	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.3	5.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.3	3.8	GO:0048733	sebaceous gland development(GO:0048733)
1.3	3.8	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.3	31.7	GO:0090630	activation of GTPase activity(GO:0090630)
1.3	7.6	GO:0035608	protein deglutamylation(GO:0035608)
1.3	1.3	GO:0036438	maintenance of lens transparency(GO:0036438)
1.3	7.6	GO:0044380	protein localization to cytoskeleton(GO:0044380)
1.3	1.3	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
1.3	5.0	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
1.3	2.5	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
1.3	2.5	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
1.3	2.5	GO:0033013	tetrapyrrole metabolic process(GO:0033013)
1.3	43.9	GO:0009060	aerobic respiration(GO:0009060)
1.2	5.0	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
1.2	3.7	GO:0048254	snoRNA localization(GO:0048254)
1.2	1.2	GO:0090281	negative regulation of calcium ion import(GO:0090281)
1.2	7.4	GO:0051016	barbed-end actin filament capping(GO:0051016)
1.2	2.5	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.2	11.1	GO:0009395	phospholipid catabolic process(GO:0009395)
1.2	8.6	GO:0008286	insulin receptor signaling pathway(GO:0008286)
1.2	28.1	GO:0006749	glutathione metabolic process(GO:0006749)
1.2	1.2	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
1.2	6.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.2	1.2	GO:0060926	cardiac pacemaker cell development(GO:0060926)
1.2	15.8	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
1.2	8.5	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
1.2	2.4	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
1.2	3.6	GO:0032204	regulation of telomere maintenance(GO:0032204)
1.2	1.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
1.2	11.9	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
1.2	8.4	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
1.2	3.6	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
1.2	2.4	GO:0046466	membrane lipid catabolic process(GO:0046466)
1.2	1.2	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
1.2	1.2	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
1.2	4.7	GO:0046415	urate metabolic process(GO:0046415)
1.2	2.4	GO:0015074	DNA integration(GO:0015074)
1.2	1.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
1.2	7.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
1.2	5.9	GO:1903725	regulation of phospholipid metabolic process(GO:1903725)
1.2	1.2	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.2	4.7	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.2	1.2	GO:0030050	vesicle transport along actin filament(GO:0030050)
1.2	10.5	GO:0045116	protein neddylation(GO:0045116)
1.2	1.2	GO:0008211	glucocorticoid metabolic process(GO:0008211)
1.2	1.2	GO:0071548	response to dexamethasone(GO:0071548)
1.2	20.9	GO:0015914	phospholipid transport(GO:0015914)
1.2	69.1	GO:0042060	wound healing(GO:0042060)
1.2	3.5	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.1	62.0	GO:0008654	phospholipid biosynthetic process(GO:0008654)
1.1	1.1	GO:0070932	histone H3 deacetylation(GO:0070932)
1.1	3.4	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.1	1.1	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
1.1	1.1	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
1.1	1.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
1.1	34.7	GO:0006633	fatty acid biosynthetic process(GO:0006633)
1.1	3.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
1.1	4.5	GO:0071467	cellular response to pH(GO:0071467)
1.1	234.8	GO:0007264	small GTPase mediated signal transduction(GO:0007264)
1.1	3.3	GO:0070995	NADPH oxidation(GO:0070995)
1.1	3.3	GO:0048599	oocyte development(GO:0048599)
1.1	2.2	GO:0035461	vitamin transmembrane transport(GO:0035461)
1.1	9.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.1	10.9	GO:0061515	myeloid cell development(GO:0061515)
1.1	3.3	GO:0006768	biotin metabolic process(GO:0006768)
1.1	1.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
1.1	3.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
1.1	8.6	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
1.1	1.1	GO:0015755	fructose transport(GO:0015755)
1.1	3.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
1.1	3.2	GO:0072348	sulfur compound transport(GO:0072348)
1.1	2.1	GO:0021783	preganglionic parasympathetic fiber development(GO:0021783)
1.1	7.4	GO:0006801	superoxide metabolic process(GO:0006801)
1.1	3.2	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
1.1	3.2	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
1.0	2.1	GO:0010225	response to UV-C(GO:0010225)
1.0	1.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.0	2.1	GO:0060046	regulation of acrosome reaction(GO:0060046)
1.0	11.4	GO:0008272	sulfate transport(GO:0008272)
1.0	31.0	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
1.0	21.7	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
1.0	2.1	GO:0071763	nuclear membrane organization(GO:0071763)
1.0	2.1	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
1.0	1.0	GO:0010869	regulation of receptor biosynthetic process(GO:0010869)
1.0	11.2	GO:0034587	piRNA metabolic process(GO:0034587)
1.0	31.5	GO:0000209	protein polyubiquitination(GO:0000209)
1.0	3.0	GO:0042116	macrophage activation(GO:0042116)
1.0	10.1	GO:1901998	toxin transport(GO:1901998)
1.0	9.1	GO:0001890	placenta development(GO:0001890)
1.0	1.0	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.0	2.0	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
1.0	5.0	GO:0051568	histone H3-K4 methylation(GO:0051568)
1.0	76.3	GO:0051607	defense response to virus(GO:0051607)
1.0	1.0	GO:0010896	regulation of triglyceride catabolic process(GO:0010896)
1.0	3.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.0	29.6	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
1.0	3.0	GO:0048496	maintenance of organ identity(GO:0048496)
1.0	2.0	GO:0070189	kynurenine metabolic process(GO:0070189)
1.0	15.7	GO:0006446	regulation of translational initiation(GO:0006446)
1.0	17.7	GO:0007030	Golgi organization(GO:0007030)
1.0	2.9	GO:0007379	segment specification(GO:0007379)
1.0	1.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
1.0	3.9	GO:0043627	response to estrogen(GO:0043627)
1.0	6.8	GO:0003351	epithelial cilium movement(GO:0003351)
1.0	3.9	GO:0070206	protein trimerization(GO:0070206)
1.0	10.7	GO:0006829	zinc II ion transport(GO:0006829)
1.0	1.9	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
1.0	4.8	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal(GO:0003044)
1.0	2.9	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
1.0	7.6	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
1.0	2.9	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
1.0	1.0	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.9	0.9	GO:0022403	cell cycle phase(GO:0022403)
0.9	0.9	GO:0046718	viral entry into host cell(GO:0046718)
0.9	7.6	GO:0016578	histone deubiquitination(GO:0016578)
0.9	0.9	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.9	1.9	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.9	2.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.9	0.9	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.9	37.3	GO:1901568	icosanoid metabolic process(GO:0006690) fatty acid derivative metabolic process(GO:1901568)
0.9	162.2	GO:0008380	RNA splicing(GO:0008380)
0.9	7.4	GO:0050892	intestinal absorption(GO:0050892)
0.9	3.7	GO:0009404	toxin metabolic process(GO:0009404)
0.9	1.8	GO:0001779	natural killer cell differentiation(GO:0001779)
0.9	1.8	GO:0006650	glycerophospholipid metabolic process(GO:0006650)
0.9	14.6	GO:0032496	response to lipopolysaccharide(GO:0032496)
0.9	2.7	GO:0009268	response to pH(GO:0009268)
0.9	0.9	GO:0035898	parathyroid hormone secretion(GO:0035898)
0.9	0.9	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.9	0.9	GO:0040009	regulation of growth rate(GO:0040009)
0.9	5.4	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.9	1.8	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.9	11.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.9	0.9	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.9	2.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.9	15.2	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.9	9.8	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.9	6.2	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.9	17.7	GO:0001824	blastocyst development(GO:0001824)
0.9	22.0	GO:1903749	positive regulation of establishment of protein localization to mitochondrion(GO:1903749)
0.9	0.9	GO:0007140	male meiosis(GO:0007140)
0.9	4.4	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.9	2.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.9	4.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.9	5.2	GO:0007062	sister chromatid cohesion(GO:0007062)
0.9	6.9	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.9	3.4	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.9	14.6	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.9	6.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.9	3.4	GO:0015893	drug transport(GO:0015893)
0.9	4.3	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.8	6.8	GO:0051923	sulfation(GO:0051923)
0.8	54.1	GO:0071219	cellular response to molecule of bacterial origin(GO:0071219)
0.8	2.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.8	8.3	GO:0015693	magnesium ion transport(GO:0015693)
0.8	0.8	GO:0015874	norepinephrine transport(GO:0015874)
0.8	2.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.8	0.8	GO:0046173	polyol biosynthetic process(GO:0046173)
0.8	0.8	GO:0010155	regulation of proton transport(GO:0010155)
0.8	5.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.8	0.8	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.8	0.8	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.8	2.4	GO:0051125	regulation of actin nucleation(GO:0051125)
0.8	9.6	GO:0006953	acute-phase response(GO:0006953)
0.8	5.5	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.8	5.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.8	3.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.8	0.8	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.8	0.8	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.8	5.4	GO:0001675	acrosome assembly(GO:0001675)
0.8	2.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.8	2.3	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.8	16.0	GO:0030641	regulation of cellular pH(GO:0030641)
0.8	3.0	GO:0070193	synaptonemal complex organization(GO:0070193)
0.7	3.7	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.7	0.7	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.7	1.5	GO:0007099	centriole replication(GO:0007099)
0.7	4.5	GO:0070232	regulation of T cell apoptotic process(GO:0070232)
0.7	2.2	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.7	6.6	GO:0035690	cellular response to drug(GO:0035690)
0.7	5.8	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.7	2.9	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.7	12.1	GO:0035036	cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036)
0.7	0.7	GO:0033344	cholesterol efflux(GO:0033344)
0.7	7.1	GO:0055072	iron ion homeostasis(GO:0055072)
0.7	1.4	GO:0018158	protein oxidation(GO:0018158)
0.7	13.3	GO:1902652	secondary alcohol metabolic process(GO:1902652)
0.7	2.8	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.7	5.4	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.7	2.0	GO:0034982	mitochondrial protein processing(GO:0034982)
0.7	0.7	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.7	1.3	GO:0048148	behavioral response to cocaine(GO:0048148)
0.7	1.3	GO:0009957	epidermal cell fate specification(GO:0009957)
0.7	0.7	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.7	0.7	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.7	1.3	GO:0000103	sulfate assimilation(GO:0000103)
0.7	2.6	GO:1904970	brush border assembly(GO:1904970)
0.7	1.3	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.7	2.6	GO:0030101	natural killer cell activation(GO:0030101)
0.6	1.3	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.6	1.9	GO:0043687	post-translational protein modification(GO:0043687)
0.6	1.3	GO:0035112	genitalia morphogenesis(GO:0035112)
0.6	1.3	GO:0016075	rRNA catabolic process(GO:0016075)
0.6	4.4	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.6	0.6	GO:2000848	positive regulation of corticosteroid hormone secretion(GO:2000848)
0.6	1.9	GO:0016115	terpenoid catabolic process(GO:0016115)
0.6	3.0	GO:0048538	thymus development(GO:0048538)
0.6	5.4	GO:0007566	embryo implantation(GO:0007566)
0.6	1.2	GO:0009624	response to nematode(GO:0009624)
0.6	1.8	GO:0043489	RNA stabilization(GO:0043489)
0.6	7.7	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.6	25.8	GO:0050909	sensory perception of taste(GO:0050909)
0.6	0.6	GO:0019217	regulation of fatty acid metabolic process(GO:0019217)
0.6	0.6	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.6	1.2	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.6	3.5	GO:0046364	monosaccharide biosynthetic process(GO:0046364)
0.6	0.6	GO:0045851	pH reduction(GO:0045851)
0.6	1.7	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.6	3.4	GO:0015992	proton transport(GO:0015992)
0.6	6.2	GO:0006073	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.6	15.7	GO:0007059	chromosome segregation(GO:0007059)
0.6	5.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.5	11.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.5	0.5	GO:0061113	pancreas morphogenesis(GO:0061113)
0.5	103.4	GO:0007283	spermatogenesis(GO:0007283)
0.5	1.1	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.5	0.5	GO:0051702	interaction with symbiont(GO:0051702)
0.5	1.6	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.5	1.1	GO:0001659	temperature homeostasis(GO:0001659)
0.5	0.5	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.5	0.5	GO:0060285	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.5	10.7	GO:0032526	response to retinoic acid(GO:0032526)
0.5	6.1	GO:0010107	potassium ion import(GO:0010107)
0.5	0.5	GO:0015884	folic acid transport(GO:0015884)
0.5	0.5	GO:0034969	histone arginine methylation(GO:0034969) histone H4-R3 methylation(GO:0043985)
0.5	2.0	GO:0046037	GMP metabolic process(GO:0046037)
0.5	0.5	GO:0051132	NK T cell activation(GO:0051132)
0.5	1.0	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.5	0.5	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.5	0.5	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.5	0.9	GO:0009247	glycolipid biosynthetic process(GO:0009247)
0.5	3.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.5	2.8	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.5	4.7	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5	1.9	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.5	0.9	GO:0034505	tooth mineralization(GO:0034505)
0.5	0.5	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.5	5.0	GO:0006289	nucleotide-excision repair(GO:0006289)
0.5	1.4	GO:0032680	regulation of tumor necrosis factor production(GO:0032680)
0.4	1.3	GO:0045777	positive regulation of blood pressure(GO:0045777)
0.4	0.9	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.4	1.8	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.4	0.4	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.4	0.4	GO:0070988	demethylation(GO:0070988)
0.4	0.4	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.4	7.5	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.4	2.1	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.4	0.8	GO:0007343	egg activation(GO:0007343)
0.4	0.4	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.4	1.6	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
0.4	3.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.4	2.0	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.4	0.4	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.4	2.7	GO:0048747	muscle fiber development(GO:0048747)
0.4	0.8	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
0.4	0.4	GO:0036159	inner dynein arm assembly(GO:0036159)
0.4	1.5	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.4	1.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.4	2.9	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.4	12.1	GO:0006631	fatty acid metabolic process(GO:0006631)
0.4	1.1	GO:0033273	response to vitamin(GO:0033273)
0.3	0.7	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.3	4.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.3	0.7	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3	1.0	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.3	11.0	GO:0006457	protein folding(GO:0006457)
0.3	1.3	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.3	0.3	GO:0070542	response to fatty acid(GO:0070542)
0.3	0.3	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.3	0.6	GO:1901616	organic hydroxy compound catabolic process(GO:1901616)
0.3	0.9	GO:0097186	amelogenesis(GO:0097186)
0.3	0.6	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3	6.8	GO:0009636	response to toxic substance(GO:0009636)
0.3	1.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.3	0.3	GO:0002292	T cell differentiation involved in immune response(GO:0002292)
0.3	1.8	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.3	0.3	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.3	0.3	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.3	0.3	GO:0060591	chondroblast differentiation(GO:0060591)
0.3	0.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.3	1.1	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.3	1.3	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.3	0.3	GO:0099515	actin filament-based transport(GO:0099515)
0.3	0.3	GO:0016073	snRNA metabolic process(GO:0016073)
0.3	0.3	GO:1902172	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.3	2.5	GO:0045047	protein targeting to ER(GO:0045047)
0.3	0.3	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.2	1.2	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.2	56.2	GO:0006412	translation(GO:0006412)
0.2	0.5	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.2	0.2	GO:0002517	T cell tolerance induction(GO:0002517)
0.2	0.2	GO:2000833	positive regulation of steroid hormone secretion(GO:2000833)
0.2	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2	0.2	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2	2.0	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.2	12.9	GO:0042742	defense response to bacterium(GO:0042742)
0.2	1.0	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.2	0.2	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2	2.9	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
0.2	0.7	GO:0019218	regulation of steroid metabolic process(GO:0019218)
0.2	2.8	GO:0031424	keratinization(GO:0031424)
0.2	1.3	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.2	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.1	0.1	GO:0090075	relaxation of muscle(GO:0090075)
0.1	0.3	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1	1.5	GO:0019216	regulation of lipid metabolic process(GO:0019216)
0.1	1.7	GO:0070228	regulation of lymphocyte apoptotic process(GO:0070228)
0.1	0.5	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	9.8	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.1	0.4	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.1	1.0	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
0.1	0.3	GO:1903170	negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.4	GO:0007614	short-term memory(GO:0007614)
0.1	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.9	GO:0045862	positive regulation of proteolysis(GO:0045862)
0.1	0.2	GO:0045924	regulation of female receptivity(GO:0045924) positive regulation of female receptivity(GO:0045925)
0.1	0.7	GO:0034111	negative regulation of homotypic cell-cell adhesion(GO:0034111)
0.1	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.1	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.3	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.1	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.1	0.1	GO:0002638	negative regulation of immunoglobulin production(GO:0002638)
0.1	0.1	GO:1905207	regulation of cardiocyte differentiation(GO:1905207)
0.1	0.2	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.5	GO:0009267	cellular response to starvation(GO:0009267)
0.1	0.1	GO:1990266	neutrophil migration(GO:1990266)
0.1	7.2	GO:0019236	response to pheromone(GO:0019236)
0.1	0.2	GO:0006638	neutral lipid metabolic process(GO:0006638)
0.0	0.4	GO:0007602	phototransduction(GO:0007602)
0.0	0.0	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.0	10.8	GO:0050907	detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	31.1	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.1	GO:1901642	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:0043043	peptide biosynthetic process(GO:0043043)
0.0	0.1	GO:0006352	DNA-templated transcription, initiation(GO:0006352)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.0	60.1	GO:0097443	sorting endosome(GO:0097443)
16.4	65.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
15.5	31.1	GO:1990204	oxidoreductase complex(GO:1990204)
15.1	45.2	GO:1990597	AIP1-IRE1 complex(GO:1990597)
14.6	43.9	GO:0031088	platelet dense granule membrane(GO:0031088)
13.8	27.6	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
12.8	38.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
12.4	62.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
12.4	24.7	GO:0060053	neurofilament cytoskeleton(GO:0060053)
12.2	12.2	GO:0005686	U2 snRNP(GO:0005686)
11.8	59.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
11.4	45.7	GO:0071141	SMAD protein complex(GO:0071141)
11.3	11.3	GO:0030175	filopodium(GO:0030175)
11.0	32.9	GO:0097413	Lewy body(GO:0097413)
10.7	53.6	GO:0005638	lamin filament(GO:0005638)
10.7	42.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
10.7	53.3	GO:0016461	unconventional myosin complex(GO:0016461)
10.4	41.7	GO:0005726	perichromatin fibrils(GO:0005726)
10.2	30.6	GO:0097513	myosin II filament(GO:0097513)
10.1	20.2	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
10.0	10.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
10.0	30.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
10.0	79.8	GO:0005861	troponin complex(GO:0005861)
10.0	79.7	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
9.6	28.7	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
9.5	38.2	GO:0072487	MSL complex(GO:0072487)
9.5	9.5	GO:0032127	dense core granule membrane(GO:0032127)
9.5	19.0	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
9.3	83.5	GO:0002116	semaphorin receptor complex(GO:0002116)
9.1	45.6	GO:0033093	Weibel-Palade body(GO:0033093)
9.0	27.1	GO:0098552	side of membrane(GO:0098552)
8.8	61.9	GO:0070688	MLL5-L complex(GO:0070688)
8.8	17.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
8.6	60.0	GO:0042382	paraspeckles(GO:0042382)
8.6	8.6	GO:1990423	RZZ complex(GO:1990423)
8.5	68.2	GO:0030056	hemidesmosome(GO:0030056)
8.5	33.9	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
8.4	33.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
8.4	33.7	GO:0031988	membrane-bounded vesicle(GO:0031988)
8.4	33.6	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
8.4	33.5	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
8.1	40.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
7.9	23.8	GO:0000814	ESCRT II complex(GO:0000814)
7.9	55.4	GO:0005677	chromatin silencing complex(GO:0005677)
7.9	15.8	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
7.8	86.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
7.8	70.4	GO:0016600	flotillin complex(GO:0016600)
7.8	70.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
7.8	23.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
7.7	38.6	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
7.7	199.6	GO:0000407	pre-autophagosomal structure(GO:0000407)
7.7	38.3	GO:0030870	Mre11 complex(GO:0030870)
7.4	52.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
7.4	44.6	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
7.4	44.5	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
7.4	29.6	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
7.4	36.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
7.3	29.3	GO:0000322	storage vacuole(GO:0000322)
7.3	29.1	GO:0031094	platelet dense tubular network(GO:0031094)
7.1	7.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
7.0	21.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
7.0	42.0	GO:1990023	mitotic spindle midzone(GO:1990023)
6.8	27.3	GO:0031298	replication fork protection complex(GO:0031298)
6.8	20.4	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
6.7	20.1	GO:0042612	MHC class I protein complex(GO:0042612)
6.7	20.1	GO:0030027	lamellipodium(GO:0030027)
6.7	33.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
6.6	52.9	GO:0001650	fibrillar center(GO:0001650)
6.6	39.6	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
6.6	59.0	GO:0070938	contractile ring(GO:0070938)
6.5	32.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
6.5	19.5	GO:0043293	apoptosome(GO:0043293)
6.5	19.5	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
6.5	39.0	GO:0031209	SCAR complex(GO:0031209)
6.5	19.4	GO:0030125	clathrin vesicle coat(GO:0030125)
6.4	19.3	GO:0070765	gamma-secretase complex(GO:0070765)
6.4	354.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
6.4	12.8	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
6.4	275.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
6.4	38.4	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
6.4	6.4	GO:0016939	kinesin II complex(GO:0016939)
6.4	19.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
6.3	44.3	GO:0031931	TORC1 complex(GO:0031931)
6.3	56.9	GO:0042641	actomyosin(GO:0042641)
6.3	18.9	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
6.2	124.4	GO:0008305	integrin complex(GO:0008305)
6.2	55.7	GO:0031080	nuclear pore outer ring(GO:0031080)
6.2	18.5	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
6.1	18.4	GO:0097452	GAIT complex(GO:0097452)
6.1	6.1	GO:0031523	Myb complex(GO:0031523)
6.1	36.6	GO:0001739	sex chromatin(GO:0001739)
6.1	73.1	GO:0031528	microvillus membrane(GO:0031528)
6.1	24.3	GO:0005828	kinetochore microtubule(GO:0005828)
6.0	18.1	GO:0005610	laminin-5 complex(GO:0005610)
5.9	35.7	GO:0030915	Smc5-Smc6 complex(GO:0030915)
5.9	350.8	GO:0000118	histone deacetylase complex(GO:0000118)
5.9	258.4	GO:0017053	transcriptional repressor complex(GO:0017053)
5.9	35.2	GO:0005818	aster(GO:0005818)
5.9	17.6	GO:0097418	neurofibrillary tangle(GO:0097418)
5.9	23.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
5.8	186.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
5.7	377.4	GO:0030863	cortical cytoskeleton(GO:0030863)
5.7	68.6	GO:0001891	phagocytic cup(GO:0001891)
5.7	51.3	GO:0031010	ISWI-type complex(GO:0031010)
5.6	45.1	GO:0032982	myosin filament(GO:0032982)
5.6	44.5	GO:0097208	alveolar lamellar body(GO:0097208)
5.6	33.4	GO:0042629	mast cell granule(GO:0042629)
5.5	22.1	GO:0042583	chromaffin granule(GO:0042583)
5.5	49.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
5.5	16.5	GO:0005642	annulate lamellae(GO:0005642)
5.5	5.5	GO:0005663	DNA replication factor C complex(GO:0005663)
5.5	32.8	GO:0001652	granular component(GO:0001652)
5.3	16.0	GO:0032391	photoreceptor connecting cilium(GO:0032391)
5.3	21.3	GO:0000125	PCAF complex(GO:0000125)
5.3	158.0	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
5.2	67.9	GO:0036038	MKS complex(GO:0036038)
5.2	15.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
5.2	31.0	GO:0090543	Flemming body(GO:0090543)
5.1	15.4	GO:0030689	Noc complex(GO:0030689)
5.1	5.1	GO:0000791	euchromatin(GO:0000791)
5.1	5.1	GO:0061574	ASAP complex(GO:0061574)
5.1	81.5	GO:0005682	U5 snRNP(GO:0005682)
5.0	15.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
5.0	35.2	GO:0035102	PRC1 complex(GO:0035102)
5.0	134.6	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
4.9	29.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
4.9	14.7	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
4.9	112.1	GO:0031519	PcG protein complex(GO:0031519)
4.8	4.8	GO:0097512	cardiac myofibril(GO:0097512)
4.8	24.2	GO:0005827	polar microtubule(GO:0005827)
4.8	19.3	GO:0000938	GARP complex(GO:0000938)
4.8	9.6	GO:1990246	uniplex complex(GO:1990246)
4.8	9.6	GO:0005879	axonemal microtubule(GO:0005879)
4.8	43.0	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
4.8	33.4	GO:0032593	insulin-responsive compartment(GO:0032593)
4.8	47.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
4.8	33.3	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
4.8	14.3	GO:0005915	zonula adherens(GO:0005915)
4.7	42.7	GO:0005869	dynactin complex(GO:0005869)
4.7	33.1	GO:0005916	fascia adherens(GO:0005916)
4.7	9.4	GO:0005914	spot adherens junction(GO:0005914)
4.7	18.9	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
4.7	18.8	GO:0097470	ribbon synapse(GO:0097470)
4.7	14.1	GO:0036449	microtubule minus-end(GO:0036449)
4.7	14.0	GO:1990462	omegasome(GO:1990462)
4.7	79.1	GO:0045120	pronucleus(GO:0045120)
4.7	9.3	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
4.7	46.5	GO:0002102	podosome(GO:0002102)
4.6	13.9	GO:0097504	Gemini of coiled bodies(GO:0097504)
4.6	4.6	GO:0033270	paranode region of axon(GO:0033270)
4.6	9.2	GO:0005683	U7 snRNP(GO:0005683)
4.6	13.8	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
4.6	45.9	GO:0035631	CD40 receptor complex(GO:0035631)
4.6	9.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
4.6	96.1	GO:0035145	exon-exon junction complex(GO:0035145)
4.6	9.1	GO:0032432	actin filament bundle(GO:0032432)
4.6	13.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
4.5	36.4	GO:0070578	RISC-loading complex(GO:0070578)
4.5	13.6	GO:0046691	intracellular canaliculus(GO:0046691)
4.5	22.7	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
4.5	85.6	GO:0016459	myosin complex(GO:0016459)
4.5	13.5	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
4.5	344.8	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
4.5	26.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
4.5	13.4	GO:0005687	U4 snRNP(GO:0005687)
4.4	26.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
4.4	48.6	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
4.4	1091.2	GO:0005925	focal adhesion(GO:0005925)
4.4	13.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.4	95.8	GO:0030131	clathrin adaptor complex(GO:0030131)
4.4	13.1	GO:0031933	telomeric heterochromatin(GO:0031933)
4.3	26.0	GO:0042383	sarcolemma(GO:0042383)
4.3	21.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
4.3	81.4	GO:0042588	zymogen granule(GO:0042588)
4.3	77.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
4.3	12.8	GO:0005745	m-AAA complex(GO:0005745)
4.3	25.6	GO:0072557	IPAF inflammasome complex(GO:0072557)
4.2	80.2	GO:0090544	BAF-type complex(GO:0090544)
4.2	21.0	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
4.2	20.9	GO:0005796	Golgi lumen(GO:0005796)
4.2	33.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
4.2	16.6	GO:0045180	basal cortex(GO:0045180)
4.1	41.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
4.1	20.5	GO:0097431	mitotic spindle pole(GO:0097431)
4.1	20.5	GO:0048476	Holliday junction resolvase complex(GO:0048476)
4.1	16.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
4.0	8.1	GO:0033269	internode region of axon(GO:0033269)
4.0	4.0	GO:0098576	lumenal side of membrane(GO:0098576)
4.0	24.2	GO:0033061	DNA recombinase mediator complex(GO:0033061)
4.0	20.1	GO:0061617	MICOS complex(GO:0061617)
4.0	23.9	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
4.0	7.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
4.0	7.9	GO:0030132	clathrin coat of coated pit(GO:0030132)
4.0	15.8	GO:0031091	platelet alpha granule(GO:0031091)
3.9	31.5	GO:0042581	specific granule(GO:0042581)
3.9	3.9	GO:0016272	prefoldin complex(GO:0016272)
3.9	11.7	GO:0030312	external encapsulating structure(GO:0030312)
3.8	138.4	GO:0005776	autophagosome(GO:0005776)
3.8	11.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
3.8	23.0	GO:0042627	chylomicron(GO:0042627)
3.8	56.9	GO:0005719	nuclear euchromatin(GO:0005719)
3.8	83.4	GO:0030992	intraciliary transport particle B(GO:0030992)
3.8	60.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
3.7	3.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
3.7	29.5	GO:0070652	HAUS complex(GO:0070652)
3.7	18.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
3.6	10.9	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
3.6	25.4	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
3.6	54.3	GO:0030014	CCR4-NOT complex(GO:0030014)
3.6	7.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
3.6	36.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
3.6	50.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
3.6	21.5	GO:0099738	cell cortex region(GO:0099738)
3.5	10.5	GO:0005588	collagen type V trimer(GO:0005588)
3.5	21.0	GO:0042587	glycogen granule(GO:0042587)
3.5	10.5	GO:0097342	ripoptosome(GO:0097342)
3.5	34.9	GO:0005640	nuclear outer membrane(GO:0005640)
3.5	17.4	GO:0071439	clathrin complex(GO:0071439)
3.5	20.7	GO:0031932	TORC2 complex(GO:0031932)
3.5	58.7	GO:0055038	recycling endosome membrane(GO:0055038)
3.4	27.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
3.4	17.2	GO:0070695	FHF complex(GO:0070695)
3.4	34.4	GO:0071004	U2-type prespliceosome(GO:0071004)
3.4	37.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
3.4	6.8	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
3.4	57.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
3.4	34.0	GO:0031011	Ino80 complex(GO:0031011)
3.4	13.6	GO:0030914	STAGA complex(GO:0030914)
3.4	27.0	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.4	10.1	GO:0031417	NatC complex(GO:0031417)
3.4	23.6	GO:0000815	ESCRT III complex(GO:0000815)
3.4	3.4	GO:0042788	polysomal ribosome(GO:0042788)
3.4	154.5	GO:0016363	nuclear matrix(GO:0016363)
3.3	153.7	GO:0016605	PML body(GO:0016605)
3.3	23.3	GO:0033263	CORVET complex(GO:0033263)
3.3	26.4	GO:0034464	BBSome(GO:0034464)
3.3	9.9	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
3.3	62.2	GO:0000786	nucleosome(GO:0000786)
3.3	19.6	GO:0097539	ciliary transition fiber(GO:0097539)
3.3	81.5	GO:0016592	mediator complex(GO:0016592)
3.3	9.8	GO:0005833	hemoglobin complex(GO:0005833)
3.3	29.3	GO:0097546	ciliary base(GO:0097546)
3.2	22.7	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
3.2	3.2	GO:0030990	intraciliary transport particle(GO:0030990)
3.2	35.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
3.2	9.7	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
3.2	3.2	GO:0044327	dendritic spine head(GO:0044327)
3.2	9.6	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
3.2	9.6	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
3.2	38.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
3.2	34.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
3.2	12.6	GO:0032591	dendritic spine membrane(GO:0032591)
3.1	28.3	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
3.1	6.2	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
3.1	12.5	GO:0031501	mannosyltransferase complex(GO:0031501)
3.1	9.3	GO:0044194	cytolytic granule(GO:0044194)
3.1	24.8	GO:0017119	Golgi transport complex(GO:0017119)
3.1	37.1	GO:0043196	varicosity(GO:0043196)
3.1	33.8	GO:0032039	integrator complex(GO:0032039)
3.0	6.1	GO:0043259	laminin-10 complex(GO:0043259)
3.0	68.7	GO:0009925	basal plasma membrane(GO:0009925)
3.0	6.0	GO:0031261	DNA replication preinitiation complex(GO:0031261)
3.0	140.0	GO:0005811	lipid particle(GO:0005811)
2.9	153.0	GO:0016529	sarcoplasmic reticulum(GO:0016529)
2.9	20.5	GO:0043020	NADPH oxidase complex(GO:0043020)
2.9	5.8	GO:0034719	SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
2.9	97.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
2.9	5.7	GO:0043218	compact myelin(GO:0043218)
2.9	34.4	GO:0000242	pericentriolar material(GO:0000242)
2.9	8.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
2.8	8.5	GO:0010369	chromocenter(GO:0010369)
2.8	16.8	GO:0044666	MLL3/4 complex(GO:0044666)
2.8	5.6	GO:0016460	myosin II complex(GO:0016460)
2.8	326.6	GO:0005741	mitochondrial outer membrane(GO:0005741)
2.8	11.2	GO:0045298	tubulin complex(GO:0045298)
2.8	30.7	GO:0036379	myofilament(GO:0036379)
2.8	2.8	GO:0000439	core TFIIH complex(GO:0000439)
2.8	30.3	GO:0005657	replication fork(GO:0005657)
2.7	16.5	GO:0032009	early phagosome(GO:0032009)
2.7	10.9	GO:0005694	chromosome(GO:0005694)
2.7	8.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
2.7	34.8	GO:0044453	nuclear membrane part(GO:0044453)
2.7	10.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.7	48.1	GO:0015030	Cajal body(GO:0015030)
2.7	8.0	GO:0030891	VCB complex(GO:0030891)
2.7	32.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
2.7	8.0	GO:0031084	BLOC-2 complex(GO:0031084)
2.7	2.7	GO:0035748	myelin sheath abaxonal region(GO:0035748)
2.6	7.9	GO:0030688	preribosome, small subunit precursor(GO:0030688)
2.6	2.6	GO:0034399	nuclear periphery(GO:0034399)
2.6	20.8	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
2.6	5.2	GO:0030666	endocytic vesicle membrane(GO:0030666)
2.6	28.5	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
2.6	2.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
2.5	63.7	GO:0012505	endomembrane system(GO:0012505)
2.5	38.2	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.5	60.9	GO:0008023	transcription elongation factor complex(GO:0008023)
2.5	17.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
2.5	12.6	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603)
2.5	72.1	GO:0001750	photoreceptor outer segment(GO:0001750)
2.5	32.3	GO:0005774	vacuolar membrane(GO:0005774)
2.5	22.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
2.4	68.4	GO:0030136	clathrin-coated vesicle(GO:0030136)
2.4	14.6	GO:0005832	chaperonin-containing T-complex(GO:0005832)
2.4	7.3	GO:0097255	R2TP complex(GO:0097255)
2.4	7.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
2.4	21.9	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
2.4	7.3	GO:0097542	ciliary tip(GO:0097542)
2.4	4.8	GO:0000796	condensin complex(GO:0000796)
2.4	2.4	GO:1990716	axonemal central apparatus(GO:1990716)
2.4	21.7	GO:0036452	ESCRT complex(GO:0036452)
2.4	26.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
2.4	38.0	GO:0001772	immunological synapse(GO:0001772)
2.4	97.3	GO:0030139	endocytic vesicle(GO:0030139)
2.4	9.5	GO:0001520	outer dense fiber(GO:0001520)
2.4	144.6	GO:0001726	ruffle(GO:0001726)
2.4	97.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
2.3	16.4	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
2.3	16.4	GO:1990909	Wnt signalosome(GO:1990909)
2.3	46.9	GO:0031901	early endosome membrane(GO:0031901)
2.3	262.0	GO:0031965	nuclear membrane(GO:0031965)
2.3	9.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
2.3	455.5	GO:0005667	transcription factor complex(GO:0005667)
2.3	2.3	GO:0046930	pore complex(GO:0046930)
2.3	46.1	GO:0032040	small-subunit processome(GO:0032040)
2.3	181.1	GO:0072562	blood microparticle(GO:0072562)
2.3	4.5	GO:0061689	tricellular tight junction(GO:0061689)
2.3	22.7	GO:0005771	multivesicular body(GO:0005771)
2.3	34.0	GO:0000145	exocyst(GO:0000145)
2.3	11.3	GO:0034709	methylosome(GO:0034709)
2.2	15.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
2.2	8.9	GO:0031143	pseudopodium(GO:0031143)
2.2	8.9	GO:0061700	GATOR2 complex(GO:0061700)
2.2	2393.2	GO:0005654	nucleoplasm(GO:0005654)
2.2	28.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
2.2	8.9	GO:0031595	nuclear proteasome complex(GO:0031595)
2.2	13.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
2.2	229.9	GO:0005681	spliceosomal complex(GO:0005681)
2.2	129.4	GO:0005802	trans-Golgi network(GO:0005802)
2.2	8.7	GO:0071953	elastic fiber(GO:0071953)
2.2	17.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
2.2	2.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
2.2	6.5	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
2.2	10.8	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
2.2	25.9	GO:0032592	integral component of mitochondrial membrane(GO:0032592) intrinsic component of mitochondrial membrane(GO:0098573)
2.2	2.2	GO:0042827	platelet dense granule(GO:0042827)
2.1	2.1	GO:0032585	multivesicular body membrane(GO:0032585)
2.1	19.2	GO:0030126	COPI vesicle coat(GO:0030126)
2.1	27.4	GO:0005876	spindle microtubule(GO:0005876)
2.1	16.8	GO:0046581	intercellular canaliculus(GO:0046581)
2.1	104.4	GO:0005903	brush border(GO:0005903)
2.1	8.3	GO:1990111	spermatoproteasome complex(GO:1990111)
2.1	6.2	GO:0042101	T cell receptor complex(GO:0042101)
2.1	6.2	GO:0030896	checkpoint clamp complex(GO:0030896)
2.1	18.7	GO:0005868	cytoplasmic dynein complex(GO:0005868)
2.1	8.2	GO:0035861	site of double-strand break(GO:0035861)
2.0	8.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
2.0	53.2	GO:0030496	midbody(GO:0030496)
2.0	12.2	GO:0042599	lamellar body(GO:0042599)
2.0	16.2	GO:0031616	spindle pole centrosome(GO:0031616)
2.0	2.0	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.0	6.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
2.0	16.0	GO:0097225	sperm midpiece(GO:0097225)
2.0	53.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
2.0	4.0	GO:0032133	chromosome passenger complex(GO:0032133)
2.0	2.0	GO:0019814	immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
2.0	2.0	GO:0031264	death-inducing signaling complex(GO:0031264)
2.0	5.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
2.0	7.8	GO:0005874	microtubule(GO:0005874)
1.9	1.9	GO:0044294	dendritic growth cone(GO:0044294)
1.9	89.4	GO:0005769	early endosome(GO:0005769)
1.9	3.9	GO:0098536	deuterosome(GO:0098536)
1.9	1.9	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
1.9	3.7	GO:0005871	kinesin complex(GO:0005871)
1.9	57.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
1.9	5.6	GO:1990923	PET complex(GO:1990923)
1.8	47.7	GO:0016328	lateral plasma membrane(GO:0016328)
1.8	7.3	GO:0035859	Seh1-associated complex(GO:0035859)
1.8	18.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
1.8	23.4	GO:0002080	acrosomal membrane(GO:0002080)
1.8	59.1	GO:0000776	kinetochore(GO:0000776)
1.8	3.6	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
1.8	55.3	GO:0000922	spindle pole(GO:0000922)
1.8	5.3	GO:0031512	motile primary cilium(GO:0031512)
1.8	5.3	GO:0005775	vacuolar lumen(GO:0005775)
1.7	8.7	GO:0005964	phosphorylase kinase complex(GO:0005964)
1.7	3.4	GO:0097422	tubular endosome(GO:0097422)
1.7	5.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.7	52.3	GO:0005938	cell cortex(GO:0005938)
1.7	152.9	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.7	5.0	GO:0071797	LUBAC complex(GO:0071797)
1.7	10.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
1.7	8.3	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.7	1282.9	GO:0005829	cytosol(GO:0005829)
1.6	46.2	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.6	32.9	GO:0000502	proteasome complex(GO:0000502)
1.6	3.3	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
1.6	6.5	GO:0071546	pi-body(GO:0071546)
1.6	420.6	GO:0005730	nucleolus(GO:0005730)
1.6	1.6	GO:0000178	exosome (RNase complex)(GO:0000178)
1.5	3.1	GO:0005955	calcineurin complex(GO:0005955)
1.5	3.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.5	4.5	GO:0000346	transcription export complex(GO:0000346)
1.5	14.9	GO:0001527	microfibril(GO:0001527)
1.5	5.9	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.5	212.2	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.4	1.4	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
1.4	8.5	GO:0030667	secretory granule membrane(GO:0030667)
1.4	4.1	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.4	4.1	GO:0031090	organelle membrane(GO:0031090)
1.4	9.5	GO:0035869	ciliary transition zone(GO:0035869)
1.3	5.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
1.3	1507.4	GO:0070062	extracellular exosome(GO:0070062)
1.3	1.3	GO:0014704	intercalated disc(GO:0014704)
1.3	8.8	GO:0008180	COP9 signalosome(GO:0008180)
1.2	8.7	GO:0000775	chromosome, centromeric region(GO:0000775)
1.2	4.9	GO:0015629	actin cytoskeleton(GO:0015629)
1.2	2.4	GO:0044292	dendrite terminus(GO:0044292)
1.2	3.6	GO:0044232	organelle membrane contact site(GO:0044232)
1.2	4.8	GO:0005641	nuclear envelope lumen(GO:0005641)
1.2	146.1	GO:0005813	centrosome(GO:0005813)
1.1	871.5	GO:0005739	mitochondrion(GO:0005739)
1.1	4.4	GO:0032300	mismatch repair complex(GO:0032300)
1.1	15.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.1	1.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.0	32.2	GO:0031514	motile cilium(GO:0031514)
1.0	17.6	GO:0005922	connexon complex(GO:0005922)
1.0	8.3	GO:0036157	outer dynein arm(GO:0036157)
1.0	21.2	GO:0000793	condensed chromosome(GO:0000793)
1.0	1.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.9	0.9	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.9	1.8	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.9	16.8	GO:0045095	keratin filament(GO:0045095)
0.9	38.6	GO:0043292	contractile fiber(GO:0043292)
0.9	38.3	GO:0016323	basolateral plasma membrane(GO:0016323)
0.8	30.4	GO:0043296	apical junction complex(GO:0043296)
0.8	1448.0	GO:0005634	nucleus(GO:0005634)
0.7	5.8	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
0.7	0.7	GO:0051286	cell tip(GO:0051286)
0.7	1.4	GO:0045178	basal part of cell(GO:0045178)
0.7	0.7	GO:0030120	vesicle coat(GO:0030120)
0.6	10.4	GO:0005815	microtubule organizing center(GO:0005815)
0.6	10.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.6	0.6	GO:0034358	plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.6	55.8	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.6	1.7	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.6	15.7	GO:0043231	intracellular membrane-bounded organelle(GO:0043231)
0.6	3.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.5	29.2	GO:0044431	Golgi apparatus part(GO:0044431)
0.5	2.4	GO:0032426	stereocilium tip(GO:0032426)
0.4	60.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.4	1.3	GO:0032279	asymmetric synapse(GO:0032279)
0.4	2.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.4	1.1	GO:0030057	desmosome(GO:0030057)
0.3	11.9	GO:0001669	acrosomal vesicle(GO:0001669)
0.3	13.5	GO:0045177	apical part of cell(GO:0045177)
0.3	15.1	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.3	4.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	11.5	GO:0005581	collagen trimer(GO:0005581)
0.3	5.8	GO:0099513	supramolecular fiber(GO:0099512) polymeric cytoskeletal fiber(GO:0099513)
0.3	505.2	GO:0005737	cytoplasm(GO:0005737)
0.3	0.3	GO:0036128	CatSper complex(GO:0036128)
0.2	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:1990904	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
23.3	69.8	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
20.5	61.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
18.4	55.2	GO:0070644	vitamin D response element binding(GO:0070644)
18.1	108.6	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
18.1	18.1	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
17.0	84.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
15.5	108.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
15.4	15.4	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
14.5	57.9	GO:0051434	BH3 domain binding(GO:0051434)
14.2	42.5	GO:0001069	regulatory region RNA binding(GO:0001069)
14.1	56.2	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
13.8	55.3	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
13.7	41.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
13.2	39.6	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
13.1	91.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
12.7	12.7	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
12.7	38.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
12.2	36.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
12.2	24.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
12.1	12.1	GO:0016420	S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
12.0	48.2	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
12.0	12.0	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
12.0	143.5	GO:0017166	vinculin binding(GO:0017166)
11.9	35.6	GO:0050692	DBD domain binding(GO:0050692)
11.8	35.3	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
11.8	35.3	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
11.7	93.6	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
11.7	104.9	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
11.6	34.9	GO:0035877	death effector domain binding(GO:0035877)
11.5	34.6	GO:0031014	troponin T binding(GO:0031014)
10.9	32.7	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
10.9	32.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
10.9	86.8	GO:0008430	selenium binding(GO:0008430)
10.8	75.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
10.8	32.3	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
10.7	42.7	GO:0004046	aminoacylase activity(GO:0004046)
10.4	52.1	GO:0051525	NFAT protein binding(GO:0051525)
10.4	31.2	GO:0004920	interleukin-10 receptor activity(GO:0004920)
10.4	31.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
10.3	41.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
10.2	10.2	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
10.1	30.3	GO:0030172	troponin C binding(GO:0030172)
10.0	59.9	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
10.0	99.8	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
9.9	19.9	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
9.9	39.7	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
9.9	39.6	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
9.9	49.5	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
9.7	19.4	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
9.6	76.9	GO:0017154	semaphorin receptor activity(GO:0017154)
9.6	28.8	GO:1990715	mRNA CDS binding(GO:1990715)
9.5	28.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
9.4	18.9	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
9.3	27.8	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
9.3	55.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
9.0	45.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
8.9	26.8	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
8.9	35.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
8.9	26.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
8.8	26.5	GO:0004949	cannabinoid receptor activity(GO:0004949)
8.7	17.3	GO:0070878	primary miRNA binding(GO:0070878)
8.7	26.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
8.6	51.4	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
8.6	102.7	GO:0044548	S100 protein binding(GO:0044548)
8.5	42.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
8.4	33.6	GO:0000293	ferric-chelate reductase activity(GO:0000293)
8.3	50.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
8.1	24.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
8.0	24.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
8.0	31.9	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
8.0	31.9	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
7.9	55.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
7.9	23.6	GO:0031871	proteinase activated receptor binding(GO:0031871)
7.8	39.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
7.8	7.8	GO:0003696	satellite DNA binding(GO:0003696)
7.7	46.2	GO:0001727	lipid kinase activity(GO:0001727)
7.7	30.8	GO:0031720	haptoglobin binding(GO:0031720)
7.7	153.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
7.7	23.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
7.7	107.4	GO:0008307	structural constituent of muscle(GO:0008307)
7.6	30.6	GO:0052717	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
7.5	15.0	GO:0042609	CD4 receptor binding(GO:0042609)
7.5	60.0	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
7.5	74.7	GO:0008432	JUN kinase binding(GO:0008432)
7.5	22.4	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
7.5	59.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
7.4	37.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
7.3	36.6	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
7.3	43.8	GO:0008199	ferric iron binding(GO:0008199)
7.3	50.9	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
7.2	28.9	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
7.2	7.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
7.2	14.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
7.2	7.2	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
7.1	14.3	GO:0030911	TPR domain binding(GO:0030911)
7.1	64.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
7.1	21.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
7.1	21.3	GO:0019961	interferon binding(GO:0019961)
7.1	141.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
7.1	21.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
7.0	27.9	GO:0043515	kinetochore binding(GO:0043515)
6.9	97.2	GO:0008143	poly(A) binding(GO:0008143)
6.9	55.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
6.9	20.8	GO:0005128	erythropoietin receptor binding(GO:0005128)
6.9	20.6	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
6.8	27.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
6.7	33.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
6.7	74.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
6.7	26.9	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
6.7	40.3	GO:0042974	retinoic acid receptor binding(GO:0042974)
6.7	86.8	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
6.7	20.0	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
6.6	26.5	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
6.6	19.8	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
6.6	26.2	GO:0009374	biotin binding(GO:0009374)
6.5	6.5	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
6.5	26.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
6.5	26.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
6.5	19.5	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
6.5	129.7	GO:0017025	TBP-class protein binding(GO:0017025)
6.5	19.4	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
6.5	135.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
6.4	19.2	GO:0045134	uridine-diphosphatase activity(GO:0045134)
6.4	6.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
6.3	19.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
6.3	25.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
6.3	189.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
6.3	18.9	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
6.3	6.3	GO:0050693	LBD domain binding(GO:0050693)
6.3	50.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
6.3	25.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
6.2	24.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
6.2	18.5	GO:0015220	choline transmembrane transporter activity(GO:0015220)
6.1	24.6	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
6.1	12.3	GO:0038181	bile acid receptor activity(GO:0038181)
6.1	48.7	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
6.0	42.2	GO:0018634	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
6.0	24.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
6.0	6.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
5.9	23.7	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
5.9	53.1	GO:0004017	adenylate kinase activity(GO:0004017)
5.9	52.8	GO:0019869	chloride channel inhibitor activity(GO:0019869)
5.8	17.3	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
5.8	28.8	GO:0016841	ammonia-lyase activity(GO:0016841)
5.7	34.5	GO:0004311	farnesyltranstransferase activity(GO:0004311)
5.7	40.2	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
5.7	34.4	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
5.7	22.9	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
5.7	5.7	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
5.7	90.6	GO:0046965	retinoid X receptor binding(GO:0046965)
5.6	16.8	GO:0001032	RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
5.6	39.0	GO:0042809	vitamin D receptor binding(GO:0042809)
5.5	16.6	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
5.5	22.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
5.5	71.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
5.5	27.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
5.4	21.8	GO:0050897	cobalt ion binding(GO:0050897)
5.4	21.7	GO:0042134	rRNA primary transcript binding(GO:0042134)
5.4	65.0	GO:0070300	phosphatidic acid binding(GO:0070300)
5.4	48.5	GO:0051010	microtubule plus-end binding(GO:0051010)
5.4	16.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
5.4	43.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
5.4	21.5	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558)
5.4	10.7	GO:0015928	fucosidase activity(GO:0015928)
5.4	75.0	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
5.4	32.1	GO:0050700	CARD domain binding(GO:0050700)
5.3	48.1	GO:0031996	thioesterase binding(GO:0031996)
5.3	5.3	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
5.3	26.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
5.3	15.8	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
5.3	42.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
5.2	42.0	GO:0015168	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
5.2	26.0	GO:0097322	7SK snRNA binding(GO:0097322)
5.2	15.6	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
5.2	20.7	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
5.2	25.8	GO:0004668	protein-arginine deiminase activity(GO:0004668)
5.1	10.3	GO:0030519	snoRNP binding(GO:0030519)
5.1	51.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
5.1	35.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
5.1	45.7	GO:0005123	death receptor binding(GO:0005123)
5.1	10.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
5.1	35.5	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
5.1	65.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
5.1	10.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
5.1	30.4	GO:0051400	BH domain binding(GO:0051400)
5.1	5.1	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
5.0	95.8	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
5.0	25.2	GO:0035184	histone threonine kinase activity(GO:0035184)
5.0	10.1	GO:1990188	euchromatin binding(GO:1990188)
5.0	10.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
5.0	15.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
5.0	10.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
5.0	14.9	GO:0008158	hedgehog receptor activity(GO:0008158)
5.0	89.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
4.9	9.9	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
4.9	14.8	GO:0042731	PH domain binding(GO:0042731)
4.9	14.8	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
4.9	34.5	GO:0019966	interleukin-1 binding(GO:0019966)
4.9	9.8	GO:0031721	hemoglobin alpha binding(GO:0031721)
4.9	48.7	GO:0035497	cAMP response element binding(GO:0035497)
4.9	150.9	GO:0008536	Ran GTPase binding(GO:0008536)
4.9	53.5	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
4.8	38.8	GO:0001222	transcription corepressor binding(GO:0001222)
4.8	57.9	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
4.8	4.8	GO:0017098	sulfonylurea receptor binding(GO:0017098)
4.8	19.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
4.8	52.7	GO:0046966	thyroid hormone receptor binding(GO:0046966)
4.8	23.9	GO:0008097	5S rRNA binding(GO:0008097)
4.8	14.4	GO:0000339	RNA cap binding(GO:0000339)
4.8	9.6	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
4.8	28.6	GO:0008641	small protein activating enzyme activity(GO:0008641)
4.8	33.3	GO:0031432	titin binding(GO:0031432)
4.7	47.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
4.7	18.9	GO:0030274	LIM domain binding(GO:0030274)
4.7	37.7	GO:1990405	protein antigen binding(GO:1990405)
4.7	28.2	GO:0015288	porin activity(GO:0015288)
4.7	9.4	GO:0045340	mercury ion binding(GO:0045340)
4.7	32.8	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
4.7	14.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
4.7	18.6	GO:0043560	insulin receptor substrate binding(GO:0043560)
4.6	13.9	GO:0004104	cholinesterase activity(GO:0004104)
4.6	13.9	GO:0004832	valine-tRNA ligase activity(GO:0004832)
4.6	23.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
4.6	13.8	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
4.6	9.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
4.6	4.6	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
4.6	110.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
4.6	41.4	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
4.6	55.1	GO:0005521	lamin binding(GO:0005521)
4.6	9.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
4.6	9.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
4.6	197.3	GO:0070491	repressing transcription factor binding(GO:0070491)
4.6	13.7	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
4.6	18.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
4.6	22.8	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
4.6	18.2	GO:0005534	galactose binding(GO:0005534)
4.5	40.9	GO:0018447	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
4.5	9.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
4.5	22.6	GO:0031749	D2 dopamine receptor binding(GO:0031749)
4.5	18.0	GO:0000405	bubble DNA binding(GO:0000405)
4.5	4.5	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
4.5	17.9	GO:0038132	neuregulin binding(GO:0038132)
4.5	22.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
4.5	4.5	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
4.4	4.4	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
4.4	4.4	GO:0031852	mu-type opioid receptor binding(GO:0031852)
4.4	150.4	GO:0004402	histone acetyltransferase activity(GO:0004402)
4.4	4.4	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
4.4	52.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
4.4	8.8	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
4.4	13.2	GO:0070097	delta-catenin binding(GO:0070097)
4.4	8.8	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
4.4	39.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
4.4	121.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
4.3	17.4	GO:0034235	GPI anchor binding(GO:0034235)
4.3	4.3	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
4.3	21.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
4.3	68.9	GO:0005112	Notch binding(GO:0005112)
4.3	29.8	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
4.3	17.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
4.3	21.3	GO:0070728	leucine binding(GO:0070728)
4.3	42.5	GO:0070412	R-SMAD binding(GO:0070412)
4.2	8.5	GO:0019959	interleukin-8 binding(GO:0019959)
4.2	8.5	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
4.2	29.7	GO:0019957	C-C chemokine binding(GO:0019957)
4.2	21.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
4.2	8.4	GO:0030620	U2 snRNA binding(GO:0030620)
4.2	16.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
4.2	33.6	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
4.2	33.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
4.2	4.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
4.2	12.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
4.2	29.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
4.2	8.3	GO:0070573	metallodipeptidase activity(GO:0070573)
4.2	12.5	GO:0019767	IgE receptor activity(GO:0019767)
4.2	20.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
4.1	29.0	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
4.1	4.1	GO:0010181	FMN binding(GO:0010181)
4.1	41.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
4.1	4.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
4.1	12.3	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
4.1	24.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
4.1	12.3	GO:0071987	WD40-repeat domain binding(GO:0071987)
4.1	20.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
4.1	12.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
4.0	20.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
4.0	8.1	GO:0016803	ether hydrolase activity(GO:0016803)
4.0	4.0	GO:0008169	C-methyltransferase activity(GO:0008169) 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity(GO:0008425) quinone cofactor methyltransferase activity(GO:0030580)
4.0	4.0	GO:0019825	oxygen binding(GO:0019825)
4.0	20.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
4.0	52.2	GO:0001784	phosphotyrosine binding(GO:0001784)
4.0	99.8	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
4.0	4.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
4.0	8.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
4.0	55.6	GO:0017049	GTP-Rho binding(GO:0017049)
4.0	15.9	GO:0042015	interleukin-20 binding(GO:0042015)
4.0	7.9	GO:0038100	nodal binding(GO:0038100)
4.0	15.9	GO:0015057	thrombin receptor activity(GO:0015057)
4.0	7.9	GO:0070051	fibrinogen binding(GO:0070051)
3.9	98.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
3.9	19.7	GO:0043522	leucine zipper domain binding(GO:0043522)
3.9	11.8	GO:0035514	DNA demethylase activity(GO:0035514)
3.9	11.7	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
3.9	27.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
3.9	42.6	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
3.9	38.7	GO:0000400	four-way junction DNA binding(GO:0000400)
3.9	54.0	GO:0050681	androgen receptor binding(GO:0050681)
3.8	15.4	GO:0015232	heme transporter activity(GO:0015232)
3.8	3.8	GO:0031705	bombesin receptor binding(GO:0031705)
3.8	15.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
3.8	7.6	GO:0070410	co-SMAD binding(GO:0070410)
3.8	145.1	GO:0003684	damaged DNA binding(GO:0003684)
3.8	15.3	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
3.8	19.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
3.8	19.0	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
3.8	7.6	GO:0043559	insulin binding(GO:0043559)
3.8	7.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
3.8	162.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
3.8	11.3	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
3.8	26.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
3.7	67.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
3.7	7.5	GO:0070698	type I activin receptor binding(GO:0070698)
3.7	33.6	GO:0001055	RNA polymerase II activity(GO:0001055)
3.7	37.3	GO:0004568	chitinase activity(GO:0004568)
3.7	63.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
3.7	18.6	GO:0017040	ceramidase activity(GO:0017040)
3.7	33.5	GO:0030983	mismatched DNA binding(GO:0030983)
3.7	7.4	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
3.7	11.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
3.7	18.4	GO:0035174	histone serine kinase activity(GO:0035174)
3.7	14.6	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
3.7	7.3	GO:0016778	diphosphotransferase activity(GO:0016778)
3.6	14.6	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
3.6	10.9	GO:0001849	complement component C1q binding(GO:0001849)
3.6	14.5	GO:0035325	Toll-like receptor binding(GO:0035325)
3.6	10.8	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.6	18.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
3.6	7.2	GO:0034618	arginine binding(GO:0034618)
3.6	10.8	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
3.6	10.8	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
3.6	17.9	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
3.6	39.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
3.6	10.8	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
3.6	35.8	GO:0004016	adenylate cyclase activity(GO:0004016)
3.6	10.7	GO:0030492	hemoglobin binding(GO:0030492)
3.6	17.9	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
3.6	21.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
3.6	17.8	GO:1990239	steroid hormone binding(GO:1990239)
3.6	39.2	GO:0019789	SUMO transferase activity(GO:0019789)
3.6	10.7	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
3.6	10.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
3.6	21.3	GO:1990446	U1 snRNP binding(GO:1990446)
3.6	21.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
3.5	14.2	GO:0005344	oxygen transporter activity(GO:0005344)
3.5	14.2	GO:0032036	myosin heavy chain binding(GO:0032036)
3.5	14.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
3.5	14.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
3.5	21.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
3.5	7.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
3.5	10.5	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
3.5	87.3	GO:0043236	laminin binding(GO:0043236)
3.5	34.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
3.5	163.6	GO:0003743	translation initiation factor activity(GO:0003743)
3.5	6.9	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
3.5	55.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
3.5	13.8	GO:0016361	activin receptor activity, type I(GO:0016361)
3.4	6.9	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
3.4	10.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
3.4	6.8	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
3.4	23.9	GO:0016208	AMP binding(GO:0016208)
3.4	40.8	GO:0070577	lysine-acetylated histone binding(GO:0070577)
3.4	33.9	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
3.4	16.9	GO:0019784	NEDD8-specific protease activity(GO:0019784)
3.4	23.6	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
3.4	20.2	GO:1990459	transferrin receptor binding(GO:1990459)
3.4	27.0	GO:0070569	uridylyltransferase activity(GO:0070569)
3.4	10.1	GO:0055100	adiponectin binding(GO:0055100)
3.4	33.6	GO:0045294	alpha-catenin binding(GO:0045294)
3.4	10.1	GO:0000182	rDNA binding(GO:0000182)
3.4	13.4	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
3.4	6.7	GO:0070034	telomerase RNA binding(GO:0070034)
3.4	20.1	GO:0050321	tau-protein kinase activity(GO:0050321)
3.3	13.4	GO:0070513	death domain binding(GO:0070513)
3.3	3.3	GO:0035197	siRNA binding(GO:0035197)
3.3	6.7	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
3.3	23.4	GO:0070063	RNA polymerase binding(GO:0070063)
3.3	30.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.3	10.0	GO:0030350	iron-responsive element binding(GO:0030350)
3.3	20.0	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
3.3	13.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
3.3	212.0	GO:0005178	integrin binding(GO:0005178)
3.3	16.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
3.3	39.6	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
3.3	42.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
3.3	26.4	GO:0032452	histone demethylase activity(GO:0032452)
3.3	29.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
3.3	6.5	GO:0032552	deoxyribonucleotide binding(GO:0032552)
3.3	13.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
3.2	32.5	GO:0052773	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
3.2	42.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
3.2	32.3	GO:0017160	Ral GTPase binding(GO:0017160)
3.2	6.4	GO:0019237	centromeric DNA binding(GO:0019237)
3.2	9.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
3.2	16.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
3.2	6.4	GO:0004126	cytidine deaminase activity(GO:0004126)
3.2	9.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.2	9.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
3.2	38.4	GO:0008327	methyl-CpG binding(GO:0008327)
3.2	16.0	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
3.2	19.1	GO:0060590	ATPase activator activity(GO:0001671) ATPase regulator activity(GO:0060590)
3.2	44.5	GO:0035035	histone acetyltransferase binding(GO:0035035)
3.2	6.4	GO:0015923	mannosidase activity(GO:0015923)
3.2	31.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
3.2	19.0	GO:0008420	CTD phosphatase activity(GO:0008420)
3.1	9.4	GO:0005372	water transmembrane transporter activity(GO:0005372)
3.1	159.7	GO:0042826	histone deacetylase binding(GO:0042826)
3.1	12.5	GO:0035591	signaling adaptor activity(GO:0035591)
3.1	3.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
3.1	3.1	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
3.1	6.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
3.1	77.7	GO:0015485	cholesterol binding(GO:0015485)
3.1	3.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
3.1	49.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
3.1	3.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
3.1	27.9	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
3.1	157.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
3.1	12.3	GO:0030984	kininogen binding(GO:0030984)
3.1	15.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
3.1	9.2	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
3.1	6.1	GO:0004127	cytidylate kinase activity(GO:0004127)
3.1	186.2	GO:0001047	core promoter binding(GO:0001047)
3.0	12.2	GO:0004594	pantothenate kinase activity(GO:0004594)
3.0	24.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
3.0	6.1	GO:0004103	choline kinase activity(GO:0004103)
3.0	9.1	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
3.0	9.1	GO:0019770	IgG receptor activity(GO:0019770)
3.0	21.2	GO:0046790	virion binding(GO:0046790)
3.0	9.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
3.0	24.1	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
3.0	45.2	GO:0005158	insulin receptor binding(GO:0005158)
3.0	12.0	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
3.0	15.1	GO:0070694	purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
3.0	12.0	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
3.0	59.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.0	3.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
3.0	273.8	GO:0017137	Rab GTPase binding(GO:0017137)
3.0	3.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
3.0	14.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
3.0	11.8	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
3.0	5.9	GO:0070717	poly-purine tract binding(GO:0070717)
2.9	5.9	GO:0016428	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
2.9	8.8	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
2.9	2.9	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
2.9	26.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
2.9	29.2	GO:0042162	telomeric DNA binding(GO:0042162)
2.9	2.9	GO:0016530	metallochaperone activity(GO:0016530)
2.9	2.9	GO:0004924	oncostatin-M receptor activity(GO:0004924)
2.9	43.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
2.9	34.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
2.9	5.8	GO:1990226	histone methyltransferase binding(GO:1990226)
2.9	5.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.9	5.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.9	8.6	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
2.9	14.4	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.9	2.9	GO:0005131	growth hormone receptor binding(GO:0005131)
2.9	17.2	GO:0050733	RS domain binding(GO:0050733)
2.9	25.7	GO:0051879	Hsp90 protein binding(GO:0051879)
2.8	39.7	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
2.8	8.5	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
2.8	33.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
2.8	8.4	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
2.8	8.4	GO:0004385	guanylate kinase activity(GO:0004385)
2.8	2.8	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
2.8	19.5	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
2.8	2.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
2.8	92.0	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
2.8	8.4	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.8	13.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
2.8	2.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.8	8.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.8	80.2	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
2.8	24.9	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.8	16.5	GO:0043024	ribosomal small subunit binding(GO:0043024)
2.8	5.5	GO:0015925	galactosidase activity(GO:0015925)
2.8	2.8	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
2.7	2.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
2.7	62.9	GO:0050699	WW domain binding(GO:0050699)
2.7	2.7	GO:0004622	lysophospholipase activity(GO:0004622)
2.7	10.9	GO:0010521	telomerase inhibitor activity(GO:0010521)
2.7	29.9	GO:0043531	ADP binding(GO:0043531)
2.7	2.7	GO:0017081	chloride channel regulator activity(GO:0017081)
2.7	16.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.7	260.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
2.7	8.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
2.7	13.4	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
2.7	5.3	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.7	45.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
2.7	82.6	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
2.7	77.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
2.7	2.7	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
2.7	395.9	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
2.7	18.6	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
2.6	47.3	GO:0004521	endoribonuclease activity(GO:0004521)
2.6	7.9	GO:0004967	glucagon receptor activity(GO:0004967)
2.6	15.7	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.6	70.7	GO:0005507	copper ion binding(GO:0005507)
2.6	2.6	GO:0035671	enone reductase activity(GO:0035671)
2.6	73.2	GO:0005484	SNAP receptor activity(GO:0005484)
2.6	39.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
2.6	49.6	GO:0030515	snoRNA binding(GO:0030515)
2.6	7.8	GO:0016842	amidine-lyase activity(GO:0016842)
2.6	7.8	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
2.6	23.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
2.6	23.4	GO:0031369	translation initiation factor binding(GO:0031369)
2.6	44.1	GO:0048365	Rac GTPase binding(GO:0048365)
2.6	7.8	GO:0017089	glycolipid transporter activity(GO:0017089)
2.6	10.3	GO:0004035	alkaline phosphatase activity(GO:0004035)
2.6	7.7	GO:0019808	polyamine binding(GO:0019808)
2.6	15.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
2.6	10.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
2.6	38.4	GO:0045502	dynein binding(GO:0045502)
2.5	2.5	GO:0004305	ethanolamine kinase activity(GO:0004305)
2.5	53.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
2.5	111.5	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
2.5	121.4	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
2.5	10.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
2.5	7.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
2.5	20.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
2.5	7.5	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
2.5	20.0	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
2.5	10.0	GO:0070567	cytidylyltransferase activity(GO:0070567)
2.5	69.8	GO:0016830	carbon-carbon lyase activity(GO:0016830)
2.5	29.8	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
2.5	108.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.5	14.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
2.4	361.4	GO:0005096	GTPase activator activity(GO:0005096)
2.4	4.9	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
2.4	7.3	GO:0000171	ribonuclease MRP activity(GO:0000171)
2.4	24.3	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
2.4	4.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
2.4	7.3	GO:0019213	deacetylase activity(GO:0019213)
2.4	21.8	GO:0030955	potassium ion binding(GO:0030955)
2.4	7.3	GO:0004064	arylesterase activity(GO:0004064)
2.4	7.3	GO:0005275	amine transmembrane transporter activity(GO:0005275)
2.4	9.7	GO:0030742	GTP-dependent protein binding(GO:0030742)
2.4	4.8	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.4	7.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.4	14.4	GO:0045296	cadherin binding(GO:0045296)
2.4	40.9	GO:0008483	transaminase activity(GO:0008483)
2.4	7.2	GO:0043199	sulfate binding(GO:0043199)
2.4	59.9	GO:0030674	protein binding, bridging(GO:0030674)
2.4	119.1	GO:0051020	GTPase binding(GO:0051020)
2.4	9.5	GO:0035473	lipase binding(GO:0035473)
2.4	168.7	GO:0008174	mRNA methyltransferase activity(GO:0008174)
2.4	11.9	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
2.4	7.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
2.4	90.0	GO:0003725	double-stranded RNA binding(GO:0003725)
2.4	4.7	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.4	7.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
2.4	7.1	GO:0004771	sterol esterase activity(GO:0004771)
2.4	2.4	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.3	21.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
2.3	4.7	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
2.3	9.4	GO:0004966	galanin receptor activity(GO:0004966)
2.3	100.7	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
2.3	4.7	GO:0008142	oxysterol binding(GO:0008142)
2.3	7.0	GO:1990932	5.8S rRNA binding(GO:1990932)
2.3	2.3	GO:0004461	lactose synthase activity(GO:0004461)
2.3	30.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
2.3	18.6	GO:0001530	lipopolysaccharide binding(GO:0001530)
2.3	20.9	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
2.3	7.0	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
2.3	2.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.3	11.6	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
2.3	16.1	GO:0097602	cullin family protein binding(GO:0097602)
2.3	4.6	GO:0010997	anaphase-promoting complex binding(GO:0010997)
2.3	9.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
2.3	50.4	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
2.3	2.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
2.3	4.6	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
2.3	9.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
2.3	4.5	GO:0000104	succinate dehydrogenase activity(GO:0000104)
2.3	24.9	GO:0015245	fatty acid transporter activity(GO:0015245)
2.3	9.1	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
2.3	4.5	GO:2001070	starch binding(GO:2001070)
2.3	15.8	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
2.3	29.3	GO:0017091	AU-rich element binding(GO:0017091)
2.3	27.0	GO:0001618	virus receptor activity(GO:0001618)
2.2	63.0	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
2.2	13.4	GO:0005540	hyaluronic acid binding(GO:0005540)
2.2	73.5	GO:0016836	hydro-lyase activity(GO:0016836)
2.2	13.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
2.2	48.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
2.2	6.6	GO:0097157	pre-mRNA intronic binding(GO:0097157)
2.2	19.8	GO:0004806	triglyceride lipase activity(GO:0004806)
2.2	436.6	GO:0008134	transcription factor binding(GO:0008134)
2.2	6.6	GO:0046624	sphingolipid transporter activity(GO:0046624)
2.2	4.4	GO:0051011	microtubule minus-end binding(GO:0051011)
2.2	13.1	GO:0071889	14-3-3 protein binding(GO:0071889)
2.2	43.5	GO:0004623	phospholipase A2 activity(GO:0004623)
2.2	141.3	GO:0003713	transcription coactivator activity(GO:0003713)
2.2	2.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
2.2	4.3	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
2.2	60.4	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
2.2	12.9	GO:0003993	acid phosphatase activity(GO:0003993)
2.1	10.7	GO:0043274	phospholipase binding(GO:0043274)
2.1	25.4	GO:0001056	RNA polymerase III activity(GO:0001056)
2.1	2.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
2.1	6.3	GO:0004359	glutaminase activity(GO:0004359)
2.1	25.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
2.1	8.3	GO:0005047	signal recognition particle binding(GO:0005047)
2.1	6.2	GO:0048038	quinone binding(GO:0048038)
2.1	4.1	GO:0008301	DNA binding, bending(GO:0008301)
2.1	18.6	GO:0034869	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
2.1	8.3	GO:0015266	protein channel activity(GO:0015266)
2.1	14.5	GO:0005523	tropomyosin binding(GO:0005523)
2.0	8.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
2.0	2.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
2.0	392.1	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
2.0	4.0	GO:0043842	Kdo transferase activity(GO:0043842)
2.0	53.8	GO:0051723	protein methylesterase activity(GO:0051723)
2.0	19.9	GO:0000989	transcription factor activity, transcription factor binding(GO:0000989)
2.0	29.9	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.0	7.9	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.0	13.8	GO:0039706	co-receptor binding(GO:0039706)
2.0	7.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
2.0	17.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
2.0	57.0	GO:0044823	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
2.0	5.9	GO:0035613	RNA stem-loop binding(GO:0035613)
1.9	11.7	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.9	11.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
1.9	1.9	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
1.9	52.1	GO:0030551	cyclic nucleotide binding(GO:0030551)
1.9	40.3	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
1.9	23.0	GO:0016918	retinal binding(GO:0016918)
1.9	13.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
1.9	9.6	GO:0019534	toxin transporter activity(GO:0019534)
1.9	9.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.9	49.6	GO:0003697	single-stranded DNA binding(GO:0003697)
1.9	7.6	GO:0005113	patched binding(GO:0005113)
1.9	58.6	GO:0005132	type I interferon receptor binding(GO:0005132)
1.9	7.6	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.9	3.8	GO:0016018	cyclosporin A binding(GO:0016018)
1.9	13.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
1.9	5.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.9	3.7	GO:0019107	myristoyltransferase activity(GO:0019107)
1.9	1.9	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.8	1.8	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
1.8	14.7	GO:0032451	demethylase activity(GO:0032451)
1.8	40.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
1.8	18.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
1.8	7.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.8	14.5	GO:0043014	alpha-tubulin binding(GO:0043014)
1.8	3.6	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.8	19.7	GO:0008308	voltage-gated anion channel activity(GO:0008308)
1.8	3.6	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.8	7.1	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.8	3.6	GO:0031433	telethonin binding(GO:0031433)
1.8	12.4	GO:0051787	misfolded protein binding(GO:0051787)
1.8	17.6	GO:0031593	polyubiquitin binding(GO:0031593)
1.8	12.3	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.7	7.0	GO:0071253	connexin binding(GO:0071253)
1.7	1.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.7	96.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.7	5.1	GO:0098634	protein binding involved in cell-matrix adhesion(GO:0098634)
1.7	13.7	GO:0016929	SUMO-specific protease activity(GO:0016929)
1.7	1.7	GO:0015927	trehalase activity(GO:0015927)
1.7	189.2	GO:0008234	cysteine-type peptidase activity(GO:0008234)
1.7	15.3	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.7	5.0	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
1.7	69.5	GO:0002020	protease binding(GO:0002020)
1.7	84.2	GO:0017124	SH3 domain binding(GO:0017124)
1.6	41.0	GO:0016748	succinyltransferase activity(GO:0016748)
1.6	4.9	GO:0035257	nuclear hormone receptor binding(GO:0035257)
1.6	3.3	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
1.6	4.9	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.6	4.9	GO:0001846	opsonin binding(GO:0001846)
1.6	9.7	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
1.6	1.6	GO:1904680	peptide transmembrane transporter activity(GO:1904680)
1.6	3.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.6	4.8	GO:0070815	procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.6	15.6	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
1.6	4.7	GO:0005536	glucose binding(GO:0005536)
1.6	28.1	GO:0043130	ubiquitin binding(GO:0043130)
1.6	4.7	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.6	10.9	GO:0043955	acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
1.5	26.2	GO:0003746	translation elongation factor activity(GO:0003746)
1.5	1.5	GO:0034061	DNA polymerase activity(GO:0034061)
1.5	15.2	GO:0019206	nucleoside kinase activity(GO:0019206)
1.5	10.7	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
1.5	42.5	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812)
1.5	6.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
1.5	1.5	GO:0070087	chromo shadow domain binding(GO:0070087)
1.5	19.6	GO:0004745	retinol dehydrogenase activity(GO:0004745)
1.5	340.2	GO:0032561	guanyl ribonucleotide binding(GO:0032561)
1.5	4.5	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
1.5	4.5	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
1.5	14.8	GO:0015238	drug transmembrane transporter activity(GO:0015238)
1.5	8.9	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.5	1.5	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
1.5	115.9	GO:0003712	transcription cofactor activity(GO:0003712)
1.5	33.7	GO:0004540	ribonuclease activity(GO:0004540)
1.5	23.4	GO:0003785	actin monomer binding(GO:0003785)
1.5	835.3	GO:0044822	poly(A) RNA binding(GO:0044822)
1.5	5.8	GO:0004519	endonuclease activity(GO:0004519)
1.4	7.2	GO:0042805	actinin binding(GO:0042805)
1.4	5.7	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
1.4	5.6	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.4	4.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.4	2.8	GO:0001758	retinal dehydrogenase activity(GO:0001758)
1.4	2.8	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.4	15.2	GO:0043022	ribosome binding(GO:0043022)
1.4	1.4	GO:0070052	collagen V binding(GO:0070052)
1.4	4.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.4	91.4	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
1.4	10.9	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.3	2.7	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
1.3	5.3	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
1.3	2.7	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.3	157.3	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.3	4.0	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.3	1.3	GO:0008318	protein prenyltransferase activity(GO:0008318)
1.3	2.6	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.3	23.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
1.3	56.2	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
1.3	1.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
1.3	28.6	GO:0005212	structural constituent of eye lens(GO:0005212)
1.3	9.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
1.3	1.3	GO:0051373	FATZ binding(GO:0051373)
1.3	3.8	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.3	1.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
1.3	5.1	GO:0008408	3'-5' exonuclease activity(GO:0008408)
1.3	1.3	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.3	11.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.3	6.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.3	5.0	GO:0004000	adenosine deaminase activity(GO:0004000)
1.2	2.5	GO:0019862	IgA binding(GO:0019862)
1.2	8.7	GO:0001595	angiotensin receptor activity(GO:0001595)
1.2	1.2	GO:0070061	fructose binding(GO:0070061)
1.2	7.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.2	4.9	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.2	3.6	GO:0002046	opsin binding(GO:0002046)
1.2	36.3	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.2	9.6	GO:0016248	channel inhibitor activity(GO:0016248)
1.2	5.9	GO:0050431	transforming growth factor beta binding(GO:0050431)
1.2	3.5	GO:0031419	cobalamin binding(GO:0031419)
1.2	8.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.2	108.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
1.2	10.5	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
1.2	1.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
1.2	12.7	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
1.2	1.2	GO:0019960	C-X3-C chemokine binding(GO:0019960)
1.2	110.8	GO:0003735	structural constituent of ribosome(GO:0003735)
1.1	24.1	GO:0005518	collagen binding(GO:0005518)
1.1	4.5	GO:0050051	alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
1.1	2.3	GO:0032794	GTPase activating protein binding(GO:0032794)
1.1	6.8	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.1	21.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.1	12.4	GO:0034792	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) DNA-N1-methyladenine dioxygenase activity(GO:0043734) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
1.1	6.8	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.1	3.4	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
1.1	3.4	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.1	10.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
1.1	2.2	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
1.1	5.5	GO:0031849	olfactory receptor binding(GO:0031849)
1.1	18.7	GO:0048020	CCR chemokine receptor binding(GO:0048020)
1.1	8.8	GO:0023026	MHC class II protein complex binding(GO:0023026)
1.1	1.1	GO:0031701	angiotensin receptor binding(GO:0031701)
1.1	1.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.1	1.1	GO:0034584	piRNA binding(GO:0034584)
1.1	3.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
1.1	6.5	GO:0070700	BMP receptor binding(GO:0070700)
1.1	3.2	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.1	13.9	GO:0015926	glucosidase activity(GO:0015926)
1.1	19.3	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.1	26.6	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
1.1	1.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
1.0	3.1	GO:0070182	DNA polymerase binding(GO:0070182)
1.0	10.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.0	41.4	GO:0008565	protein transporter activity(GO:0008565)
1.0	30.8	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
1.0	3.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
1.0	171.6	GO:0003779	actin binding(GO:0003779)
1.0	2.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.0	1.0	GO:0060229	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
1.0	3.9	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.0	4.9	GO:0004994	somatostatin receptor activity(GO:0004994)
1.0	7.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
1.0	11.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.9	0.9	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.9	6.3	GO:0003796	lysozyme activity(GO:0003796)
0.9	2.7	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.9	1.7	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.9	2.6	GO:0019976	interleukin-2 binding(GO:0019976)
0.9	0.9	GO:0051920	peroxiredoxin activity(GO:0051920)
0.9	51.5	GO:0003774	motor activity(GO:0003774)
0.9	0.9	GO:0005499	vitamin D binding(GO:0005499)
0.8	38.0	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.8	20.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.8	274.8	GO:0008270	zinc ion binding(GO:0008270)
0.8	5.8	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.8	7.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.8	2.4	GO:0016015	morphogen activity(GO:0016015)
0.8	10.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.8	1.5	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.8	37.5	GO:0019902	phosphatase binding(GO:0019902)
0.8	3.8	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.8	4.6	GO:0016853	isomerase activity(GO:0016853)
0.8	15.8	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.7	3.7	GO:0015643	toxic substance binding(GO:0015643)
0.7	3.6	GO:0031491	nucleosome binding(GO:0031491)
0.7	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.7	1.4	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.7	1.4	GO:0051870	methotrexate binding(GO:0051870)
0.7	1.4	GO:0008172	S-methyltransferase activity(GO:0008172)
0.7	12.8	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.7	0.7	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.7	3.5	GO:0019865	immunoglobulin binding(GO:0019865)
0.7	2.7	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.6	5.0	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.6	0.6	GO:0030151	molybdenum ion binding(GO:0030151)
0.6	1.2	GO:0004518	nuclease activity(GO:0004518)
0.6	11.2	GO:0042605	peptide antigen binding(GO:0042605)
0.6	1.2	GO:0046848	hydroxyapatite binding(GO:0046848)
0.6	1.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.6	0.6	GO:0030523	dihydrolipoamide S-acyltransferase activity(GO:0030523)
0.6	2.8	GO:0002039	p53 binding(GO:0002039)
0.6	3.4	GO:0042287	MHC protein binding(GO:0042287)
0.6	0.6	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.6	11.6	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.5	0.5	GO:0003880	protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.5	1.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.5	5.8	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5	1.1	GO:0034452	dynactin binding(GO:0034452)
0.5	0.5	GO:0032934	sterol binding(GO:0032934)
0.5	1.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.5	6.0	GO:0022829	wide pore channel activity(GO:0022829)
0.5	73.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.5	3.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.5	1.5	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.5	1.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.5	0.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	1.4	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.5	0.5	GO:0055102	lipase inhibitor activity(GO:0055102)
0.5	12.2	GO:0005319	lipid transporter activity(GO:0005319)
0.4	1.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.4	1.6	GO:0042379	chemokine receptor binding(GO:0042379)
0.4	0.8	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.4	4.2	GO:0004177	aminopeptidase activity(GO:0004177)
0.4	1.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.4	63.1	GO:0005198	structural molecule activity(GO:0005198)
0.4	1.4	GO:0042301	phosphate ion binding(GO:0042301)
0.4	13.3	GO:0008527	taste receptor activity(GO:0008527)
0.3	1.4	GO:0001972	retinoic acid binding(GO:0001972)
0.3	0.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	1.6	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	0.6	GO:0031404	chloride ion binding(GO:0031404)
0.3	1.2	GO:0019209	kinase activator activity(GO:0019209)
0.3	9.6	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.3	2.3	GO:0003823	antigen binding(GO:0003823)
0.3	3.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	0.3	GO:0043422	protein kinase B binding(GO:0043422)
0.3	0.8	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3	0.3	GO:0032190	acrosin binding(GO:0032190)
0.3	0.5	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3	9.2	GO:0042393	histone binding(GO:0042393)
0.3	0.5	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.3	1.5	GO:0015026	coreceptor activity(GO:0015026)
0.2	1.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	17.6	GO:0005125	cytokine activity(GO:0005125)
0.2	21.7	GO:0005179	hormone activity(GO:0005179)
0.2	3.6	GO:0030414	peptidase inhibitor activity(GO:0030414)
0.2	0.6	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.2	126.2	GO:0003677	DNA binding(GO:0003677)
0.2	0.8	GO:0016783	sulfurtransferase activity(GO:0016783)
0.2	0.7	GO:0016936	galactoside binding(GO:0016936)
0.2	2.0	GO:0042056	chemoattractant activity(GO:0042056)
0.2	0.7	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	0.5	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	4.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	21.7	GO:0003676	nucleic acid binding(GO:0003676)
0.2	1.6	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.1	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.1	0.3	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
0.1	0.1	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	11.0	GO:0005550	pheromone binding(GO:0005550)
0.1	0.1	GO:0018585	fluorene oxygenase activity(GO:0018585)
0.1	0.3	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	99.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	1.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.1	GO:0008061	chitin binding(GO:0008061)
0.1	0.2	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.6	GO:0005186	pheromone activity(GO:0005186)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.3	11.3	PID S1P S1P2 PATHWAY	S1P2 pathway
10.2	215.1	PID IGF1 PATHWAY	IGF1 pathway
10.2	122.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
10.1	91.3	ST STAT3 PATHWAY	STAT3 Pathway
9.8	234.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
9.5	255.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
9.3	18.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
8.8	123.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
8.3	58.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
8.0	79.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
7.9	118.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
7.9	110.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
7.9	118.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
7.8	109.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
7.6	342.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
7.4	185.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
6.9	130.9	PID NECTIN PATHWAY	Nectin adhesion pathway
6.8	94.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
6.8	162.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
6.7	161.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
6.6	263.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
6.6	217.0	PID ILK PATHWAY	Integrin-linked kinase signaling
6.5	130.6	PID AURORA A PATHWAY	Aurora A signaling
6.2	43.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
6.0	24.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
6.0	226.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
6.0	59.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
5.9	23.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
5.9	70.6	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
5.9	41.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
5.7	182.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
5.6	5.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
5.6	244.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
5.5	27.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
5.5	131.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
5.4	211.3	PID P53 REGULATION PATHWAY	p53 pathway
5.4	32.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
5.4	107.4	PID RHOA PATHWAY	RhoA signaling pathway
5.2	104.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
5.1	244.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
5.1	60.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
5.0	85.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
5.0	10.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
5.0	59.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
4.9	24.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
4.9	4.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
4.8	125.1	PID RAC1 PATHWAY	RAC1 signaling pathway
4.8	57.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
4.8	9.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
4.8	158.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
4.8	61.8	PID MYC PATHWAY	C-MYC pathway
4.5	4.5	ST GA12 PATHWAY	G alpha 12 Pathway
4.5	18.1	PID TRAIL PATHWAY	TRAIL signaling pathway
4.5	31.4	PID CD40 PATHWAY	CD40/CD40L signaling
4.4	53.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
4.4	39.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
4.3	78.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
4.3	34.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
4.3	21.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
4.3	4.3	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
4.2	114.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
4.2	139.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
4.2	125.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
4.2	104.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
4.1	48.9	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
4.0	4.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
3.7	107.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
3.7	11.1	PID ALK2 PATHWAY	ALK2 signaling events
3.7	58.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
3.7	33.1	PID IL1 PATHWAY	IL1-mediated signaling events
3.6	57.7	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
3.5	81.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
3.5	21.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
3.5	48.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
3.4	60.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
3.3	67.0	PID PLK1 PATHWAY	PLK1 signaling events
3.3	49.2	PID TNF PATHWAY	TNF receptor signaling pathway
3.3	42.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
3.2	42.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
3.2	90.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
3.1	22.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
3.1	119.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
3.1	34.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
3.1	9.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
3.1	190.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
3.0	18.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
3.0	54.3	PID ATR PATHWAY	ATR signaling pathway
3.0	3.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
3.0	75.0	PID P73PATHWAY	p73 transcription factor network
2.9	14.4	PID ATM PATHWAY	ATM pathway
2.9	31.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
2.9	40.0	PID ARF 3PATHWAY	Arf1 pathway
2.9	20.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
2.8	5.6	PID IL5 PATHWAY	IL5-mediated signaling events
2.7	65.5	PID AURORA B PATHWAY	Aurora B signaling
2.7	21.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
2.7	16.0	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
2.7	90.3	PID CMYB PATHWAY	C-MYB transcription factor network
2.6	55.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
2.6	15.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
2.6	26.0	PID BCR 5PATHWAY	BCR signaling pathway
2.6	44.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
2.6	28.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
2.6	7.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
2.5	40.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
2.5	7.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
2.5	32.0	PID RAS PATHWAY	Regulation of Ras family activation
2.4	39.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
2.4	17.0	ST GAQ PATHWAY	G alpha q Pathway
2.4	21.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
2.4	16.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
2.3	16.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
2.3	18.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
2.2	4.4	ST G ALPHA S PATHWAY	G alpha s Pathway
2.2	28.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
2.0	6.1	PID IFNG PATHWAY	IFN-gamma pathway
2.0	28.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
2.0	4.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.9	36.9	PID CONE PATHWAY	Visual signal transduction: Cones
1.9	7.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.8	18.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.8	21.8	PID FANCONI PATHWAY	Fanconi anemia pathway
1.7	1.7	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.7	15.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
1.7	31.0	PID MTOR 4PATHWAY	mTOR signaling pathway
1.7	5.1	PID ERBB4 PATHWAY	ErbB4 signaling events
1.7	8.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
1.7	46.6	PID NOTCH PATHWAY	Notch signaling pathway
1.6	18.1	PID BARD1 PATHWAY	BARD1 signaling events
1.6	6.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.6	3.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.5	20.1	PID AP1 PATHWAY	AP-1 transcription factor network
1.5	42.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
1.5	191.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.5	7.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.4	8.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
1.4	7.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
1.4	14.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
1.3	1.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
1.3	2.5	SIG CHEMOTAXIS	Genes related to chemotaxis
1.3	3.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.2	3.5	PID IL27 PATHWAY	IL27-mediated signaling events
1.1	5.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
1.1	210.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.1	13.1	PID ALK1 PATHWAY	ALK1 signaling events
1.1	3.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.1	2.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
1.1	11.6	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
1.0	18.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
1.0	10.3	PID ARF6 PATHWAY	Arf6 signaling events
1.0	12.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.0	11.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.9	1.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.9	7.5	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.9	1.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.9	5.5	PID ENDOTHELIN PATHWAY	Endothelins
0.9	7.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.9	11.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.9	6.0	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.8	5.8	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.7	29.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.6	7.6	PID IL23 PATHWAY	IL23-mediated signaling events
0.5	8.2	PID LKB1 PATHWAY	LKB1 signaling events
0.5	3.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.5	2.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.5	62.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.5	0.9	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.5	3.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.4	1.8	PID FOXO PATHWAY	FoxO family signaling
0.4	0.8	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	3.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	0.6	PID S1P S1P4 PATHWAY	S1P4 pathway
0.3	2.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3	3.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	3.0	PID E2F PATHWAY	E2F transcription factor network
0.1	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	1.0	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.4	15.4	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
13.0	234.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
13.0	13.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
10.4	166.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
10.1	50.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
9.9	237.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
9.8	9.8	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
9.0	170.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
8.6	77.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
8.5	119.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
8.4	67.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
8.3	91.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
8.0	31.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
7.9	151.0	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
7.9	79.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
7.7	38.7	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
7.5	74.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
7.5	104.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
7.4	59.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
7.4	51.8	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
7.4	66.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
7.2	43.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
7.2	194.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
7.2	165.3	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
7.1	113.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
7.1	91.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
6.8	41.0	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
6.8	75.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
6.6	157.6	REACTOME G1 PHASE	Genes involved in G1 Phase
6.5	104.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
6.5	65.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
6.5	58.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
6.4	70.7	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
6.3	37.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
6.2	68.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
6.2	55.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
6.0	6.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
6.0	53.6	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
5.9	35.6	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
5.9	59.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
5.9	87.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
5.8	81.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
5.8	46.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
5.6	129.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
5.6	128.8	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
5.6	33.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
5.6	33.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
5.6	508.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
5.5	104.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
5.4	32.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
5.4	204.7	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
5.2	157.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
5.2	120.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
5.2	36.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
5.1	20.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
5.0	5.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
4.9	4.9	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
4.8	48.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
4.8	130.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
4.8	47.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
4.7	4.7	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
4.7	75.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
4.7	97.9	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
4.6	60.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
4.6	9.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
4.6	46.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
4.6	82.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
4.6	13.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
4.6	41.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
4.5	44.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
4.5	26.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
4.5	76.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
4.5	286.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
4.4	13.3	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
4.4	22.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
4.3	108.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
4.2	46.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
4.1	41.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
4.1	28.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
4.1	143.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.1	16.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
4.1	40.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
4.0	4.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
4.0	63.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
4.0	7.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
3.9	27.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
3.9	11.7	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
3.9	120.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
3.9	57.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
3.9	73.3	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
3.8	61.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
3.8	26.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
3.8	41.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
3.8	95.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
3.8	353.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
3.8	113.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
3.8	11.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
3.8	15.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
3.8	234.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
3.7	37.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
3.7	168.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
3.7	310.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
3.7	29.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
3.6	107.3	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
3.6	50.1	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
3.5	10.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
3.4	72.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
3.4	24.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
3.4	10.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
3.4	27.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
3.4	124.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
3.2	29.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
3.2	13.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
3.2	35.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
3.2	32.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
3.2	99.4	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
3.2	38.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
3.2	63.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
3.1	3.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
3.1	15.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
3.1	12.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
3.1	12.5	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
3.0	30.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
3.0	3.0	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
3.0	24.0	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
3.0	38.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.9	35.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
2.9	17.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
2.9	5.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
2.8	119.6	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
2.8	98.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
2.8	5.6	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
2.7	16.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
2.7	92.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
2.7	16.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
2.7	59.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
2.6	10.5	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
2.6	2.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.6	18.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
2.6	10.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
2.6	28.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
2.6	23.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
2.6	41.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
2.5	15.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
2.5	12.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
2.5	2.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
2.4	51.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
2.4	21.6	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
2.4	28.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.4	14.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
2.4	202.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
2.4	11.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
2.4	9.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
2.3	18.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
2.3	34.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
2.3	46.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
2.3	39.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
2.3	22.7	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
2.2	4.5	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
2.2	24.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
2.2	22.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
2.2	29.1	REACTOME ACTIVATED TLR4 SIGNALLING	Genes involved in Activated TLR4 signalling
2.2	95.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
2.2	8.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.1	51.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
2.1	10.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.1	40.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
2.1	16.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
2.1	8.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
2.1	35.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
2.0	14.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
2.0	54.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
2.0	12.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
2.0	74.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
1.9	5.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
1.9	23.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.9	28.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
1.9	24.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
1.8	16.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.8	14.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
1.8	267.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.8	3.5	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
1.8	5.3	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
1.7	10.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
1.7	22.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.7	18.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.7	17.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.7	10.2	REACTOME APOPTOSIS	Genes involved in Apoptosis
1.6	47.5	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
1.6	21.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
1.6	27.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.6	19.3	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
1.6	23.8	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.6	11.0	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
1.5	13.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.5	41.0	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.5	10.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.5	5.8	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
1.5	21.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.5	4.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.4	4.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
1.4	49.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
1.4	9.8	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
1.4	6.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
1.4	34.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
1.3	5.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
1.3	7.9	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
1.3	15.9	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
1.3	7.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
1.3	15.2	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
1.3	15.1	REACTOME METABOLISM OF RNA	Genes involved in Metabolism of RNA
1.3	15.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
1.3	7.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.3	17.6	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
1.2	34.9	REACTOME TRANSLATION	Genes involved in Translation
1.2	14.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
1.2	11.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.2	10.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
1.2	47.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.2	10.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
1.1	2.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.1	7.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
1.1	4.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
1.1	1.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.1	3.3	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
1.0	2.1	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
1.0	6.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
1.0	15.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.9	30.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.9	7.4	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.9	16.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.8	2.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.8	56.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.8	4.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.8	13.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.8	14.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.8	9.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.7	7.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.7	12.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.7	7.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.7	7.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.7	19.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.6	6.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.6	4.4	REACTOME OPSINS	Genes involved in Opsins
0.5	37.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.5	0.5	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.5	2.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.4	9.1	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.4	67.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.3	2.8	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.3	14.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	6.4	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.3	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	4.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.4	REACTOME DEFENSINS	Genes involved in Defensins
0.1	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.8	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine

Results for Elf1_Elf2_Etv2_Elf4

Z-value: 11.43

Motif logo

Transcription factors associated with Elf1_Elf2_Etv2_Elf4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Elf1_Elf2_Etv2_Elf4 motif across conditions

Conditions sorted by the z-value of the Elf1_Elf2_Etv2_Elf4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf1_Elf2_Etv2_Elf4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: