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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for En2

Z-value: 2.73

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Transcription factors associated with En2

Gene Symbol	Gene ID	Gene Info
En2 Ensembl NCBI MGI UniProt	ENSMUSG00000039095.7	engrailed 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_28165381_28165955	En2	26	0.974532	0.74	1.6e-10	Click!
chr5_28158467_28158630	En2	7146	0.187049	0.73	1.8e-10	Click!
chr5_28165997_28166156	En2	382	0.840959	0.69	6.7e-09	Click!
chr5_28123165_28123337	En2	42443	0.112147	0.59	2.6e-06	Click!

Activity of the En2 motif across conditions

Conditions sorted by the z-value of the En2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_69303567_69303898	15.47	Gm36487	predicted gene, 36487	12262	0.17
chr2_63963076_63963322	14.54	Fign	fidgetin	134789	0.06
chr11_112501711_112502406	13.63	BC006965	cDNA sequence BC006965	167340	0.04
chr12_44839950_44840386	13.61	Gm15901	predicted gene 15901	83012	0.1
chr10_73821665_73822034	12.91	Pcdh15	protocadherin 15	18	0.99
chr2_50971381_50971555	12.75	Gm13498	predicted gene 13498	61784	0.14
chr12_56004549_56004776	12.72	Gm5183	predicted gene 5183	45871	0.13
chr4_21689447_21689958	12.24	Prdm13	PR domain containing 13	3739	0.21
chr6_12337029_12337231	12.12	Thsd7a	thrombospondin, type I, domain containing 7A	12437	0.3
chr10_8348667_8348983	11.88	Ust	uronyl-2-sulfotransferase	46583	0.19
chr13_52457883_52458068	11.80	Diras2	DIRAS family, GTP-binding RAS-like 2	73304	0.12
chr8_69160881_69161314	11.77	Lzts1	leucine zipper, putative tumor suppressor 1	20144	0.15
chr17_49044163_49044341	11.64	Gm44304	predicted gene, 44304	52181	0.14
chr3_35090595_35090820	11.58	Mir6378	microRNA 6378	168056	0.03
chr8_26265045_26265237	11.44	Gm31727	predicted gene, 31727	1836	0.25
chr11_43548063_43548966	11.35	Ccnjl	cyclin J-like	19268	0.13
chr13_63985759_63985962	11.21	Gm7695	predicted gene 7695	39339	0.14
chr13_101203160_101203326	11.13	5930438M14Rik	RIKEN cDNA 5930438M14 gene	28884	0.19
chr8_12126295_12126640	10.93	A230072I06Rik	RIKEN cDNA A230072I06 gene	152352	0.03
chr13_99444397_99444879	10.72	Map1b	microtubule-associated protein 1B	171	0.95
chr11_39596506_39596789	10.71	Gm12131	predicted gene 12131	131065	0.06
chr5_37768904_37769238	10.69	Cytl1	cytokine-like 1	31791	0.15
chr2_54265163_54265368	10.57	Gm14035	predicted gene 14035	18850	0.21
chr17_17402608_17403030	10.44	Lix1	limb and CNS expressed 1	147	0.94
chr1_42695585_42695788	10.37	Pou3f3	POU domain, class 3, transcription factor 3	82	0.89
chr15_44705846_44706012	10.36	Sybu	syntabulin (syntaxin-interacting)	41859	0.15
chr10_87489779_87490093	10.27	Ascl1	achaete-scute family bHLH transcription factor 1	3724	0.24
chr6_40024235_40024578	10.26	Gm37995	predicted gene, 37995	2488	0.33
chr12_51002047_51002408	10.18	Gm40421	predicted gene, 40421	2646	0.28
chr11_21713646_21713804	10.03	Wdpcp	WD repeat containing planar cell polarity effector	18596	0.2
chr8_13454338_13454755	9.97	Tmem255b	transmembrane protein 255B	932	0.51
chr10_51153683_51154077	9.97	Gm26257	predicted gene, 26257	28419	0.22
chr5_116895407_116895611	9.81	Gm43122	predicted gene 43122	64955	0.1
chr4_48779650_48779836	9.81	Gm24573	predicted gene, 24573	16781	0.2
chr2_146710690_146711112	9.79	Gm14111	predicted gene 14111	44804	0.18
chr2_6594788_6595061	9.69	Celf2	CUGBP, Elav-like family member 2	2124	0.42
chr12_13845175_13845385	9.55	Gm49374	predicted gene, 49374	52943	0.11
chr3_98990771_98991097	9.45	5730437C11Rik	RIKEN cDNA 5730437C11 gene	49678	0.1
chr3_34504632_34504783	9.42	Gm29135	predicted gene 29135	22500	0.16
chr3_141943522_141943718	9.38	Bmpr1b	bone morphogenetic protein receptor, type 1B	12097	0.29
chr5_103335878_103336033	9.28	Gm42619	predicted gene 42619	8017	0.16
chr10_87500912_87501095	9.23	Gm48120	predicted gene, 48120	6859	0.19
chr13_29349395_29349902	9.17	Gm11364	predicted gene 11364	113028	0.07
chr18_17383276_17383802	9.16	4921533I20Rik	Riken cDNA 4921533I20 gene	63809	0.15
chr18_42739913_42740099	9.14	C030004G16Rik	RIKEN cDNA C030004G16 gene	117547	0.05
chr6_126645496_126645701	9.14	Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	785	0.67
chr11_43747463_43748363	9.13	Ttc1	tetratricopeptide repeat domain 1	69	0.98
chr2_46297559_46297710	9.11	Gm23072	predicted gene, 23072	8702	0.3
chr14_35112923_35113111	9.09	Gm49034	predicted gene, 49034	106421	0.07
chr17_84749518_84749672	9.08	Lrpprc	leucine-rich PPR-motif containing	1667	0.35
chr5_62581784_62581962	9.08	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	30501	0.17
chr9_65267989_65268185	9.06	Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	2264	0.19
chr9_5752747_5752938	9.00	Gm48506	predicted gene, 48506	43937	0.19
chr8_118004421_118004600	8.92	Gm25200	predicted gene, 25200	116444	0.06
chr6_77075373_77076013	8.88	Ctnna2	catenin (cadherin associated protein), alpha 2	68250	0.13
chr12_29279690_29280795	8.86	Gm6989	predicted gene 6989	37326	0.21
chr15_59040434_59041094	8.83	Mtss1	MTSS I-BAR domain containing 1	167	0.96
chr17_69686012_69686193	8.83	Gm49895	predicted gene, 49895	89910	0.08
chr18_21185734_21186067	8.80	Gm6378	predicted pseudogene 6378	108791	0.05
chr8_23360756_23361303	8.79	Sfrp1	secreted frizzled-related protein 1	50473	0.12
chr4_141011762_141012413	8.78	Mfap2	microfibrillar-associated protein 2	1443	0.27
chr3_66102086_66102567	8.66	Gm36973	predicted gene, 36973	2521	0.19
chr9_23378360_23378672	8.55	Bmper	BMP-binding endothelial regulator	4584	0.36
chr13_82620860_82621103	8.51	Mir3961	microRNA 3961	77352	0.12
chr9_37028261_37028476	8.48	n-R5s82	nuclear encoded rRNA 5S 82	1969	0.29
chr6_144251546_144251744	8.46	Sox5	SRY (sex determining region Y)-box 5	42077	0.21
chr2_146724098_146724249	8.45	Gm14111	predicted gene 14111	31532	0.22
chr10_100111276_100111504	8.38	Kitl	kit ligand	23334	0.13
chr8_93917610_93917784	8.36	Gm24159	predicted gene, 24159	16239	0.16
chr5_107497898_107498054	8.36	Btbd8	BTB (POZ) domain containing 8	197	0.9
chr11_44785172_44785367	8.34	Gm12158	predicted gene 12158	122593	0.05
chr12_45929501_45929668	8.34	Gm24948	predicted gene, 24948	54759	0.17
chr10_19396813_19397100	8.33	Olig3	oligodendrocyte transcription factor 3	40423	0.16
chr3_94465598_94465829	8.31	Riiad1	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1	7209	0.08
chr8_26255231_26255419	8.26	Gm31727	predicted gene, 31727	11652	0.12
chr4_96969208_96969597	8.22	Gm27521	predicted gene, 27521	52382	0.15
chr17_11927079_11927230	8.19	Prkn	parkin RBR E3 ubiquitin protein ligase	81944	0.1
chr17_90892371_90892658	8.16	4930480K15Rik	RIKEN cDNA 4930480K15 gene	31345	0.22
chr10_101373884_101374182	8.15	Gm19233	predicted gene, 19233	102412	0.08
chr2_97543948_97544112	8.15	Lrrc4c	leucine rich repeat containing 4C	75941	0.11
chr15_52384572_52384762	8.07	Gm41322	predicted gene, 41322	60455	0.12
chr4_125545547_125545968	8.02	Mir692-2	microRNA 692-2	41008	0.15
chr16_59854456_59854822	8.01	Epha6	Eph receptor A6	151082	0.04
chr13_115911152_115911322	7.97	Gm18135	predicted gene, 18135	140301	0.05
chr12_86911691_86911906	7.90	Irf2bpl	interferon regulatory factor 2 binding protein-like	27000	0.14
chr5_54411627_54411808	7.90	Gm10440	predicted gene 10440	61726	0.15
chr19_47493646_47493894	7.87	Stn1	STN1, CST complex subunit	15003	0.15
chr4_109977408_109977780	7.85	Dmrta2os	doublesex and mab-3 related transcription factor like family A2, opposite strand	103	0.86
chr3_34646262_34646441	7.85	Gm42692	predicted gene 42692	3087	0.14
chr3_80802510_80803270	7.83	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	55	0.98
chr1_68046813_68046988	7.76	Gm15671	predicted gene 15671	22657	0.22
chr5_78622542_78622942	7.76	Gm43232	predicted gene 43232	82214	0.11
chrX_169838405_169838582	7.73	Mid1	midline 1	10334	0.25
chr2_6884852_6885717	7.58	Celf2	CUGBP, Elav-like family member 2	288	0.83
chr15_57590018_57590245	7.57	Gm49235	predicted gene, 49235	101260	0.06
chr3_159851998_159852454	7.53	Wls	wntless WNT ligand secretion mediator	3775	0.28
chr16_63500963_63501194	7.52	Gm49622	predicted gene, 49622	8961	0.32
chr4_39344820_39345025	7.51	Gm23607	predicted gene, 23607	49459	0.14
chr13_52562127_52562509	7.49	Syk	spleen tyrosine kinase	20855	0.22
chr7_78887666_78887880	7.49	Mir7-2	microRNA 7-2	504	0.68
chr15_64920763_64921549	7.47	Adcy8	adenylate cyclase 8	1115	0.61
chr1_41814005_41814309	7.45	Gm29260	predicted gene 29260	32349	0.25
chr9_87883201_87883375	7.44	Gm25528	predicted gene, 25528	5299	0.28
chr13_81628689_81629170	7.44	Adgrv1	adhesion G protein-coupled receptor V1	4210	0.23
chr15_95640522_95640729	7.42	Dbx2	developing brain homeobox 2	7797	0.2
chr1_4970686_4970886	7.39	Gm16041	predicted gene 16041	71	0.97
chr12_68217227_68217378	7.39	Gm47454	predicted gene, 47454	115320	0.06
chr19_21781727_21782179	7.36	Cemip2	cell migration inducing hyaluronidase 2	3565	0.26
chr1_41749293_41749469	7.36	Gm29260	predicted gene 29260	32427	0.25
chr1_89739411_89739593	7.36	Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	49661	0.13
chr4_128492137_128492443	7.35	Csmd2	CUB and Sushi multiple domains 2	15136	0.24
chr2_116042575_116042745	7.34	Meis2	Meis homeobox 2	614	0.73
chr14_80170834_80170985	7.32	Gm17923	predicted gene, 17923	44021	0.18
chr3_80607920_80608085	7.31	Gm25749	predicted gene, 25749	84311	0.1
chr18_50397132_50397306	7.30	Fam170a	family with sequence similarity 170, member A	118848	0.06
chr17_8368820_8369004	7.27	T2	brachyury 2	3484	0.15
chr13_28774697_28775021	7.26	Gm17528	predicted gene, 17528	52264	0.13
chr12_17557739_17558001	7.22	Gm36862	predicted gene, 36862	171	0.93
chr9_34712119_34712402	7.21	Gm38217	predicted gene, 38217	190505	0.03
chr12_4523765_4524306	7.18	Gm31938	predicted gene, 31938	78	0.96
chr13_84751597_84751791	7.15	Gm26913	predicted gene, 26913	60753	0.15
chr1_139346382_139347077	7.11	Crb1	crumbs family member 1, photoreceptor morphogenesis associated	18461	0.17
chr8_34325666_34325912	7.11	Gm4889	predicted gene 4889	2121	0.21
chr4_136786609_136786819	7.09	Ephb2	Eph receptor B2	49129	0.12
chr4_41727338_41727565	7.09	Arid3c	AT rich interactive domain 3C (BRIGHT-like)	2835	0.12
chr17_68560365_68560556	7.09	Gm17921	predicted gene, 17921	138451	0.05
chr3_134605538_134605802	7.08	Gm26820	predicted gene, 26820	25095	0.24
chr9_45626192_45626360	7.08	Gm22069	predicted gene, 22069	8536	0.21
chr18_47703851_47704052	7.06	Gm5236	predicted gene 5236	25816	0.18
chr15_47991044_47991322	7.04	Csmd3	CUB and Sushi multiple domains 3	10438	0.32
chrX_59241259_59241443	7.04	Gm14890	predicted gene 14890	44388	0.15
chr13_78581171_78581365	7.02	Gm48402	predicted gene, 48402	56749	0.14
chr14_100375280_100375638	7.02	Gm26367	predicted gene, 26367	43024	0.15
chr5_88583308_88583633	7.02	Rufy3	RUN and FYVE domain containing 3	43	0.97
chr6_15397521_15397861	7.02	Gm25470	predicted gene, 25470	7290	0.26
chr1_75725382_75725667	7.01	Gm5257	predicted gene 5257	89134	0.07
chr2_150735739_150736543	6.98	Gm28450	predicted gene 28450	11520	0.12
chr2_21282645_21282991	6.97	Gm13378	predicted gene 13378	38713	0.15
chr12_25871193_25871842	6.97	Gm47733	predicted gene, 47733	364	0.91
chr7_79511969_79512162	6.96	2900037B21Rik	RIKEN cDNA 2900037B21 gene	859	0.35
chr8_90576969_90577137	6.94	Gm45639	predicted gene 45639	97905	0.07
chr8_61309392_61309892	6.94	1700001D01Rik	RIKEN cDNA 1700001D01 gene	20770	0.18
chr3_57919632_57919807	6.93	Gm24531	predicted gene, 24531	2468	0.24
chr2_93227691_93228447	6.92	Tspan18	tetraspanin 18	283	0.93
chrX_61823685_61823865	6.92	Gm6743	predicted pseudogene 6743	6735	0.25
chr10_49256416_49256586	6.91	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	13465	0.18
chr18_57263021_57263225	6.90	Gm50200	predicted gene, 50200	52017	0.11
chr9_119888845_119889024	6.89	Gm2449	predicted gene 2449	5911	0.15
chr7_29071400_29071669	6.86	Gm26604	predicted gene, 26604	69	0.87
chr19_21781154_21781434	6.84	Cemip2	cell migration inducing hyaluronidase 2	2906	0.29
chr18_80040460_80040856	6.83	Pard6g	par-6 family cell polarity regulator gamma	6232	0.08
chr15_4378780_4379184	6.83	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3	3478	0.36
chr1_82324497_82324671	6.81	Rhbdd1	rhomboid domain containing 1	7942	0.18
chr13_64527016_64527226	6.80	Gm47190	predicted gene, 47190	11267	0.13
chr4_122998402_122999232	6.80	Mycl	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived	63	0.96
chrX_58445733_58445903	6.79	Gm14645	predicted gene 14645	17743	0.26
chr8_25392912_25393353	6.75	Gm39147	predicted gene, 39147	5888	0.16
chr3_110010549_110010756	6.75	Gm12535	predicted gene 12535	103268	0.07
chr5_116208794_116209040	6.74	Gm14507	predicted gene 14507	34789	0.12
chr10_67559869_67560062	6.73	4930563J15Rik	RIKEN cDNA 4930563J15 gene	10073	0.12
chr3_69709128_69709981	6.70	Rpl32-ps	ribosomal protein L32, pseudogene	7839	0.17
chr13_107407430_107407612	6.70	Apoo-ps	apolipoprotein O, pseudogene	7208	0.24
chr19_15801412_15801721	6.69	Gm50348	predicted gene, 50348	1492	0.52
chr7_132184258_132184454	6.68	Cpxm2	carboxypeptidase X 2 (M14 family)	29617	0.16
chr9_11279890_11280105	6.67	Gm18934	predicted gene, 18934	1954	0.42
chrX_58689115_58689266	6.64	Gm7071	predicted gene 7071	20466	0.21
chr7_49699721_49700100	6.62	Htatip2	HIV-1 Tat interactive protein 2	59205	0.11
chr19_15340555_15340742	6.61	Gm24319	predicted gene, 24319	339356	0.01
chr1_6752243_6752413	6.60	St18	suppression of tumorigenicity 18	14753	0.25
chr3_76654290_76654629	6.60	Fstl5	follistatin-like 5	60909	0.15
chr2_22294291_22294480	6.60	Myo3a	myosin IIIA	53328	0.16
chr14_76260875_76261070	6.59	2900040C04Rik	RIKEN cDNA 2900040C04 gene	9515	0.23
chr1_118776552_118777195	6.59	Gm28467	predicted gene 28467	33263	0.18
chr8_69149162_69149554	6.57	Lzts1	leucine zipper, putative tumor suppressor 1	8405	0.17
chr18_14844486_14844862	6.57	Gm21055	predicted gene, 21055	14006	0.21
chr13_18127101_18127252	6.57	4930448F12Rik	RIKEN cDNA 4930448F12 gene	26974	0.14
chr1_52079807_52079978	6.57	Gm28177	predicted gene 28177	2631	0.2
chr2_122351287_122351549	6.56	Shf	Src homology 2 domain containing F	2713	0.18
chr10_27103841_27103992	6.56	Lama2	laminin, alpha 2	47271	0.17
chr13_43950234_43950637	6.55	Gm2233	predicted gene 2233	1556	0.43
chr3_158559650_158560260	6.55	Lrrc7	leucine rich repeat containing 7	1381	0.57
chr16_42340863_42341164	6.55	Gap43	growth associated protein 43	362	0.91
chr11_35913497_35913742	6.53	Wwc1	WW, C2 and coiled-coil domain containing 1	37907	0.16
chr8_92167277_92167548	6.52	Gm45335	predicted gene 45335	5175	0.21
chr9_41593811_41594013	6.51	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	5418	0.12
chr6_99669465_99669765	6.49	Gm20696	predicted gene 20696	2818	0.18
chr17_88275094_88275304	6.48	1700116H05Rik	RIKEN cDNA 1700116H05 gene	30179	0.17
chr13_71165452_71165631	6.46	Mir466f-4	microRNA 466f-4	58452	0.15
chr1_25893085_25893254	6.45	Gm9884	predicted gene 9884	62512	0.08
chr13_54884713_54885019	6.43	Gm29431	predicted gene 29431	2604	0.21
chr9_61872624_61872918	6.43	Gm19208	predicted gene, 19208	21067	0.18
chr14_101055920_101056254	6.43	Prr30	proline rich 30	143982	0.04
chrX_38313231_38313611	6.42	Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	2763	0.23
chr14_104537843_104538037	6.41	Rnf219	ring finger protein 219	15295	0.18
chr8_26677560_26678005	6.40	Gm32098	predicted gene, 32098	9476	0.18
chr13_95995367_95995681	6.39	Sv2c	synaptic vesicle glycoprotein 2c	5298	0.24
chr6_23281324_23281501	6.39	C130093G08Rik	RIKEN cDNA C130093G08 gene	30279	0.15
chr18_74907209_74907702	6.38	Gm24559	predicted gene, 24559	1021	0.37
chr11_11113745_11113896	6.35	Vwc2	von Willebrand factor C domain containing 2	403	0.89
chr1_85916730_85916901	6.33	Itm2c	integral membrane protein 2C	10654	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of En2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.8	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
3.7	11.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
3.5	13.9	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
3.5	10.4	GO:0072240	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
2.7	10.8	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
2.7	8.1	GO:0060166	olfactory pit development(GO:0060166)
2.6	10.3	GO:0023041	neuronal signal transduction(GO:0023041)
2.5	22.7	GO:0050957	equilibrioception(GO:0050957)
2.2	6.5	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
1.9	13.6	GO:0016198	axon choice point recognition(GO:0016198)
1.8	1.8	GO:0097091	synaptic vesicle clustering(GO:0097091)
1.6	4.8	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
1.6	12.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
1.6	6.2	GO:0060594	mammary gland specification(GO:0060594)
1.5	7.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
1.3	5.2	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
1.2	2.5	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
1.2	4.7	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.1	4.5	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.1	4.4	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
1.1	5.4	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
1.1	5.4	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.0	3.1	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
1.0	7.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
1.0	2.0	GO:0031223	auditory behavior(GO:0031223)
1.0	2.9	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.0	4.8	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.9	1.9	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.9	4.6	GO:0036233	glycine import(GO:0036233)
0.9	3.7	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9	1.8	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.9	2.7	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.9	2.6	GO:0042126	nitrate metabolic process(GO:0042126)
0.9	2.6	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.9	7.8	GO:0071625	vocalization behavior(GO:0071625)
0.9	1.7	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.9	6.0	GO:0042118	endothelial cell activation(GO:0042118)
0.8	3.2	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.8	2.4	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.8	3.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.8	2.4	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.8	3.1	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.8	8.6	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.8	2.3	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.8	2.3	GO:0007412	axon target recognition(GO:0007412)
0.8	2.3	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.8	2.3	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.8	1.5	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.7	4.4	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.7	2.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.7	2.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.7	2.9	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.7	2.9	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.7	2.2	GO:0089700	protein kinase D signaling(GO:0089700)
0.7	5.7	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.7	2.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.7	2.8	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7	2.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.7	2.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.7	1.4	GO:1903802	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.7	2.8	GO:0060279	positive regulation of ovulation(GO:0060279)
0.7	1.4	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.6	3.9	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.6	0.6	GO:0001661	conditioned taste aversion(GO:0001661)
0.6	1.9	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.6	1.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.6	1.9	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6	1.2	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.6	2.4	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.6	0.6	GO:0021564	vagus nerve development(GO:0021564)
0.6	1.8	GO:0097090	presynaptic membrane organization(GO:0097090)
0.6	1.2	GO:0070668	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.6	4.2	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.6	7.7	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6	1.7	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.6	7.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.6	0.6	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.6	1.7	GO:0046959	habituation(GO:0046959)
0.6	2.2	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.6	3.9	GO:0006450	regulation of translational fidelity(GO:0006450)
0.6	1.1	GO:0061055	myotome development(GO:0061055)
0.6	3.3	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.5	3.3	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.5	2.2	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.5	1.6	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.5	4.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.5	1.6	GO:0001927	exocyst assembly(GO:0001927)
0.5	3.2	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
0.5	2.1	GO:0090427	activation of meiosis(GO:0090427)
0.5	1.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5	1.0	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.5	1.5	GO:0030242	pexophagy(GO:0030242)
0.5	3.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.5	1.5	GO:0009957	epidermal cell fate specification(GO:0009957)
0.5	2.0	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.5	1.0	GO:0072199	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
0.5	2.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.5	1.5	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.5	3.4	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.5	1.5	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.5	0.5	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.5	1.5	GO:0002765	immune response-inhibiting signal transduction(GO:0002765)
0.5	3.4	GO:0021559	trigeminal nerve development(GO:0021559)
0.5	1.0	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5	1.4	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.5	0.9	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.5	1.9	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.5	2.3	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.5	1.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.5	1.4	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.5	2.3	GO:1902669	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.5	1.4	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.4	1.8	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.4	1.8	GO:0060486	Clara cell differentiation(GO:0060486)
0.4	1.3	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.4	2.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.4	1.7	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.4	3.0	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4	2.2	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.4	0.9	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.4	2.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.4	6.4	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.4	2.5	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.4	1.7	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.4	0.8	GO:0035262	gonad morphogenesis(GO:0035262)
0.4	0.8	GO:0046103	inosine biosynthetic process(GO:0046103)
0.4	0.8	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.4	0.4	GO:0090494	catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.4	0.4	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.4	1.2	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.4	1.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.4	1.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.4	2.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.4	1.2	GO:0006553	lysine metabolic process(GO:0006553)
0.4	6.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.4	1.6	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4	2.0	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.4	0.8	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.4	0.8	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.4	0.8	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.4	1.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.4	1.9	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4	0.8	GO:0021978	telencephalon regionalization(GO:0021978)
0.4	8.9	GO:0006376	mRNA splice site selection(GO:0006376)
0.4	0.4	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.4	2.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.4	3.1	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.4	1.5	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.4	1.5	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.4	1.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.4	2.6	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.4	1.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.4	0.7	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4	1.5	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.4	0.7	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.4	1.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.4	5.1	GO:0046549	retinal cone cell development(GO:0046549)
0.4	1.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.4	0.7	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.4	0.7	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.4	2.5	GO:0071435	potassium ion export(GO:0071435)
0.4	2.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.4	0.4	GO:0097195	pilomotor reflex(GO:0097195)
0.4	0.7	GO:0060005	vestibular reflex(GO:0060005)
0.3	2.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.3	2.8	GO:0060134	prepulse inhibition(GO:0060134)
0.3	0.3	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.3	5.8	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.3	1.4	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3	1.4	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.3	1.7	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.3	2.7	GO:0001504	neurotransmitter uptake(GO:0001504)
0.3	1.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.3	2.6	GO:0060179	male mating behavior(GO:0060179)
0.3	0.3	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.3	1.0	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.3	1.3	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
0.3	0.6	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.3	0.3	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
0.3	0.9	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.3	0.6	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3	1.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3	0.9	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3	0.9	GO:0032474	otolith morphogenesis(GO:0032474)
0.3	0.9	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.3	5.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.3	1.4	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.3	3.4	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.3	0.8	GO:0010996	response to auditory stimulus(GO:0010996)
0.3	0.6	GO:0033058	directional locomotion(GO:0033058)
0.3	1.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.3	0.8	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.3	0.8	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3	1.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.3	0.5	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.3	0.8	GO:0072092	ureteric bud invasion(GO:0072092)
0.3	0.3	GO:0060174	limb bud formation(GO:0060174)
0.3	1.6	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.3	0.3	GO:0052330	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.3	1.3	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.3	0.5	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3	0.8	GO:0003344	pericardium morphogenesis(GO:0003344)
0.3	0.3	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3	0.8	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.3	3.4	GO:0016082	synaptic vesicle priming(GO:0016082)
0.3	1.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.3	0.5	GO:0003032	detection of oxygen(GO:0003032)
0.3	4.4	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3	0.8	GO:0032252	secretory granule localization(GO:0032252)
0.3	0.8	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3	0.5	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3	0.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.3	1.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.3	0.5	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.2	2.0	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.2	0.5	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	0.7	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2	0.5	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.2	0.7	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.2	1.5	GO:0015884	folic acid transport(GO:0015884)
0.2	0.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.2	0.7	GO:0002215	defense response to nematode(GO:0002215)
0.2	3.6	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2	1.9	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	1.4	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.2	1.7	GO:0035641	locomotory exploration behavior(GO:0035641)
0.2	1.6	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.2	1.6	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	0.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.2	0.7	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.2	1.1	GO:0019532	oxalate transport(GO:0019532)
0.2	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	0.7	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2	18.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	0.4	GO:0042473	outer ear morphogenesis(GO:0042473)
0.2	1.5	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2	5.0	GO:0007616	long-term memory(GO:0007616)
0.2	0.2	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2	0.6	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.2	0.6	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	1.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2	0.6	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.2	1.3	GO:0003338	metanephros morphogenesis(GO:0003338)
0.2	0.4	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.2	0.8	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.2	0.6	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.2	0.2	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.2	1.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.2	0.8	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	2.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2	0.4	GO:0046098	guanine metabolic process(GO:0046098)
0.2	0.6	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.2	0.6	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	0.6	GO:0002339	B cell selection(GO:0002339)
0.2	0.6	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.2	0.6	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.2	3.5	GO:0097352	autophagosome maturation(GO:0097352)
0.2	0.8	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2	0.6	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.2	0.6	GO:0048840	otolith development(GO:0048840)
0.2	0.2	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	1.0	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2	0.8	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.2	0.9	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.2	0.6	GO:0048625	myoblast fate commitment(GO:0048625)
0.2	1.1	GO:0001964	startle response(GO:0001964)
0.2	0.9	GO:0021984	adenohypophysis development(GO:0021984)
0.2	1.7	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.2	0.2	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2	1.8	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.2	0.7	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	0.4	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.2	0.4	GO:0097576	vacuole fusion(GO:0097576)
0.2	0.9	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2	0.5	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.2	1.1	GO:0032570	response to progesterone(GO:0032570)
0.2	2.8	GO:1901381	positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2	0.3	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.2	0.5	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.2	0.3	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.2	1.4	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2	0.3	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2	0.9	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.2	0.7	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2	0.7	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.2	1.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.2	0.5	GO:0021854	hypothalamus development(GO:0021854)
0.2	0.8	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.2	0.5	GO:0051466	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2	1.8	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2	0.6	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.2	0.5	GO:0060468	prevention of polyspermy(GO:0060468)
0.2	0.6	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.5	GO:0014028	notochord formation(GO:0014028)
0.2	0.3	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.2	0.6	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.2	1.4	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.2	0.2	GO:0035483	gastric emptying(GO:0035483)
0.2	4.9	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.2	0.3	GO:0097283	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.2	0.6	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.2	7.3	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.2	0.5	GO:1902804	negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2	1.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.0	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.3	GO:0021756	striatum development(GO:0021756)
0.1	0.3	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.9	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	1.5	GO:0002329	pre-B cell differentiation(GO:0002329)
0.1	0.7	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
0.1	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.4	GO:0030421	defecation(GO:0030421)
0.1	0.3	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.1	1.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.7	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.4	GO:0002930	trabecular meshwork development(GO:0002930)
0.1	0.4	GO:1902570	protein localization to nucleolus(GO:1902570) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1	0.1	GO:0006558	L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1	0.4	GO:1990035	calcium ion import into cell(GO:1990035)
0.1	0.3	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.4	GO:0030070	insulin processing(GO:0030070)
0.1	0.3	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.1	0.7	GO:0002858	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858)
0.1	0.4	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	0.8	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.7	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.3	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.5	GO:0030091	protein repair(GO:0030091)
0.1	0.5	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.1	0.9	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.4	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.7	GO:0021542	dentate gyrus development(GO:0021542)
0.1	2.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.3	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1	0.5	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.4	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.1	0.7	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	10.5	GO:0007411	axon guidance(GO:0007411)
0.1	0.2	GO:0002086	diaphragm contraction(GO:0002086)
0.1	0.1	GO:2000410	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.1	0.4	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.1	0.9	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0021747	cochlear nucleus development(GO:0021747)
0.1	0.5	GO:0015816	glycine transport(GO:0015816)
0.1	0.5	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.8	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.1	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1	0.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.1	0.3	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.2	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.1	0.7	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	0.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	1.2	GO:0016486	peptide hormone processing(GO:0016486)
0.1	0.8	GO:0042756	drinking behavior(GO:0042756)
0.1	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.1	0.2	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	0.1	GO:0021586	pons maturation(GO:0021586)
0.1	0.1	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	1.1	GO:0006517	protein deglycosylation(GO:0006517)
0.1	0.3	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1	0.3	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1	0.4	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	0.3	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.1	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1	0.3	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.8	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1	2.8	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	0.3	GO:0009155	dGTP catabolic process(GO:0006203) purine deoxyribonucleotide catabolic process(GO:0009155) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217)
0.1	0.7	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.1	0.5	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1	1.7	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	0.2	GO:0070375	ERK5 cascade(GO:0070375)
0.1	0.7	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.9	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	0.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.9	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	0.2	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.1	0.3	GO:0035459	cargo loading into vesicle(GO:0035459)
0.1	0.6	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.1	GO:0072205	metanephric collecting duct development(GO:0072205)
0.1	0.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.7	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.1	0.1	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.1	0.4	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.1	0.6	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.1	0.3	GO:0019374	galactolipid metabolic process(GO:0019374)
0.1	0.4	GO:0046479	glycosphingolipid catabolic process(GO:0046479)
0.1	0.4	GO:0015780	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	0.1	GO:1904861	excitatory synapse assembly(GO:1904861)
0.1	0.5	GO:0008216	spermidine metabolic process(GO:0008216)
0.1	0.3	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.1	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.2	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.1	0.2	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.3	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.1	0.3	GO:0009233	menaquinone metabolic process(GO:0009233)
0.1	0.3	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.1	0.4	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1	0.2	GO:0090237	regulation of arachidonic acid secretion(GO:0090237)
0.1	0.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	0.2	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.1	0.3	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	1.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.4	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.1	0.2	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.1	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.3	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.1	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.2	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.1	0.2	GO:0097212	lysosomal membrane organization(GO:0097212)
0.1	0.3	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.1	0.1	GO:1904970	brush border assembly(GO:1904970)
0.1	0.2	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.1	0.4	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.1	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.7	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	0.1	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.1	0.1	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1	0.1	GO:0048294	negative regulation of isotype switching(GO:0045829) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.1	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	0.2	GO:0015747	urate transport(GO:0015747)
0.1	0.2	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.1	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.1	0.6	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1	0.4	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.1	0.6	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.1	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.2	GO:0060947	cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.1	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0021590	cerebellum maturation(GO:0021590)
0.1	0.1	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.1	0.1	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.1	0.4	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	0.1	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.1	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.1	0.3	GO:0048242	epinephrine secretion(GO:0048242)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.1	0.4	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.2	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.1	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.1	0.2	GO:0006702	androgen biosynthetic process(GO:0006702)
0.1	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.4	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.1	0.2	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
0.1	0.2	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.1	0.1	GO:0021871	forebrain regionalization(GO:0021871)
0.1	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.2	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.1	0.4	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.2	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.1	0.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.1	0.9	GO:0033198	response to ATP(GO:0033198)
0.1	0.1	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.1	GO:1903421	regulation of synaptic vesicle recycling(GO:1903421)
0.0	0.1	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.1	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.2	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.0	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.5	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.0	0.1	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.7	GO:0046348	amino sugar catabolic process(GO:0046348)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.3	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.1	GO:1903998	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0	0.0	GO:0003072	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0	0.0	GO:0061196	positive regulation of hair follicle maturation(GO:0048818) fungiform papilla development(GO:0061196)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.0	0.2	GO:0032048	cardiolipin metabolic process(GO:0032048)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.2	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.2	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.2	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.0	GO:0060558	regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0	0.2	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.0	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.0	0.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.0	0.3	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.5	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.3	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.9	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.2	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.6	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.3	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.3	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.3	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.0	0.0	GO:0010513	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0002666	positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.0	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.2	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.2	GO:0060547	negative regulation of necrotic cell death(GO:0060547)
0.0	0.6	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.5	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.2	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.0	GO:0033084	regulation of immature T cell proliferation in thymus(GO:0033084)
0.0	0.1	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.0	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.1	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.0	0.0	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.1	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.3	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0	0.2	GO:0097531	mast cell migration(GO:0097531)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.3	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0	0.2	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.2	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.0	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.0	0.1	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	1.1	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.1	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.2	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:0009624	response to nematode(GO:0009624)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0061010	gall bladder development(GO:0061010)
0.0	0.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.0	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.0	GO:0061308	cardiac neural crest cell development involved in heart development(GO:0061308)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.0	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.0	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.0	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.0	GO:0000032	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	1.1	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.0	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	27.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
1.7	5.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
1.2	3.6	GO:0005594	collagen type IX trimer(GO:0005594)
1.1	5.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.9	5.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.8	2.3	GO:0005899	insulin receptor complex(GO:0005899)
0.8	21.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.7	10.4	GO:0031527	filopodium membrane(GO:0031527)
0.7	8.5	GO:0043194	axon initial segment(GO:0043194)
0.7	2.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.7	1.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.7	5.2	GO:0071437	invadopodium(GO:0071437)
0.7	7.8	GO:0032426	stereocilium tip(GO:0032426)
0.6	1.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.6	16.8	GO:0032420	stereocilium(GO:0032420)
0.6	2.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.6	8.3	GO:0043196	varicosity(GO:0043196)
0.6	23.4	GO:0042734	presynaptic membrane(GO:0042734)
0.6	1.7	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.6	1.7	GO:0048179	activin receptor complex(GO:0048179)
0.6	1.7	GO:0097441	basilar dendrite(GO:0097441)
0.5	0.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.5	5.4	GO:0035253	ciliary rootlet(GO:0035253)
0.5	1.6	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.5	1.6	GO:0072534	perineuronal net(GO:0072534)
0.5	14.7	GO:0048786	presynaptic active zone(GO:0048786)
0.5	1.9	GO:0019815	B cell receptor complex(GO:0019815)
0.5	1.4	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.5	1.4	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.4	1.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.4	2.5	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4	1.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.4	1.2	GO:0070939	Dsl1p complex(GO:0070939)
0.4	2.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4	1.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.4	2.7	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4	2.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4	5.7	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4	1.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.3	5.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	1.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.3	1.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.3	3.1	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3	0.6	GO:0044393	microspike(GO:0044393)
0.3	1.1	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.3	0.8	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3	0.5	GO:0097418	neurofibrillary tangle(GO:0097418)
0.3	1.0	GO:0070876	SOSS complex(GO:0070876)
0.2	0.7	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	1.9	GO:0030991	intraciliary transport particle A(GO:0030991)
0.2	1.2	GO:0097433	dense body(GO:0097433)
0.2	1.1	GO:0044294	dendritic growth cone(GO:0044294)
0.2	0.9	GO:1990130	Iml1 complex(GO:1990130)
0.2	1.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.2	1.0	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.2	1.3	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.2	1.2	GO:0060091	kinocilium(GO:0060091)
0.2	0.4	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2	1.6	GO:0042788	polysomal ribosome(GO:0042788)
0.2	0.6	GO:0097427	microtubule bundle(GO:0097427)
0.2	0.6	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.2	0.2	GO:1990761	growth cone lamellipodium(GO:1990761)
0.2	4.0	GO:0032590	dendrite membrane(GO:0032590)
0.2	1.6	GO:0005859	muscle myosin complex(GO:0005859)
0.2	0.7	GO:0005642	annulate lamellae(GO:0005642)
0.2	0.5	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.2	1.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	1.0	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	0.5	GO:0044308	axonal spine(GO:0044308)
0.2	0.6	GO:0045098	type III intermediate filament(GO:0045098)
0.2	0.6	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	21.2	GO:0031225	anchored component of membrane(GO:0031225)
0.2	0.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	1.1	GO:0033270	paranode region of axon(GO:0033270)
0.1	1.3	GO:0032797	SMN complex(GO:0032797)
0.1	0.6	GO:0036449	microtubule minus-end(GO:0036449)
0.1	1.6	GO:0030061	mitochondrial crista(GO:0030061)
0.1	1.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.6	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.5	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	1.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.4	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	0.5	GO:0044299	C-fiber(GO:0044299)
0.1	0.4	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	1.3	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.6	GO:0043203	axon hillock(GO:0043203)
0.1	0.4	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1	0.5	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.5	GO:0045180	basal cortex(GO:0045180)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.7	GO:0005869	dynactin complex(GO:0005869)
0.1	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	1.3	GO:0031045	dense core granule(GO:0031045)
0.1	0.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	2.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.1	2.3	GO:0044447	axoneme part(GO:0044447)
0.1	0.4	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.9	GO:0030897	HOPS complex(GO:0030897)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.9	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.7	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.4	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.4	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.7	GO:0042555	MCM complex(GO:0042555)
0.1	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.3	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.2	GO:0000802	transverse filament(GO:0000802)
0.1	0.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.3	GO:0097449	astrocyte projection(GO:0097449)
0.0	1.2	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	2.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.1	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	2.5	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.0	GO:0034705	potassium channel complex(GO:0034705)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.5	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0036396	MIS complex(GO:0036396)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.0	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.0	GO:0033010	paranodal junction(GO:0033010)
0.0	0.0	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.0	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0098984	neuron to neuron synapse(GO:0098984)
0.0	0.0	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.6	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
2.8	8.5	GO:0097109	neuroligin family protein binding(GO:0097109)
2.7	10.6	GO:0035727	lysophosphatidic acid binding(GO:0035727)
2.5	12.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
2.3	4.7	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
1.9	9.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
1.4	4.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
1.3	4.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.2	3.7	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.2	8.4	GO:0003680	AT DNA binding(GO:0003680)
1.2	4.6	GO:0015375	glycine:sodium symporter activity(GO:0015375)
1.0	2.9	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.9	3.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.9	3.7	GO:0008502	melatonin receptor activity(GO:0008502)
0.9	4.6	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.9	3.6	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.9	3.5	GO:0032051	clathrin light chain binding(GO:0032051)
0.9	2.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.8	3.2	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.8	4.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.7	15.0	GO:0071837	HMG box domain binding(GO:0071837)
0.7	2.8	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.7	2.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.7	2.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7	1.3	GO:0045503	dynein light chain binding(GO:0045503)
0.7	0.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7	1.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.6	3.8	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.6	0.6	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.6	1.8	GO:0008158	hedgehog receptor activity(GO:0008158)
0.6	7.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.6	1.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.6	1.7	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6	3.9	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.6	1.7	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.6	1.7	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5	2.7	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.5	17.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.5	0.5	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5	1.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.5	2.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5	5.8	GO:0050811	GABA receptor binding(GO:0050811)
0.5	4.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5	3.4	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.5	1.4	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.5	1.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.4	5.4	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.4	1.3	GO:0051425	PTB domain binding(GO:0051425)
0.4	1.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.4	1.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	1.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.4	1.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.4	2.4	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.4	2.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4	1.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.4	1.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.4	0.8	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.4	1.9	GO:0004985	opioid receptor activity(GO:0004985)
0.4	1.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.4	1.1	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.4	2.2	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4	10.7	GO:0070888	E-box binding(GO:0070888)
0.4	1.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.4	4.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4	1.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4	1.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.4	1.8	GO:0070051	fibrinogen binding(GO:0070051)
0.4	1.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3	1.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.3	1.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.3	1.3	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.3	1.3	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.3	1.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.3	2.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3	0.9	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.3	1.5	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.3	1.2	GO:0005042	netrin receptor activity(GO:0005042)
0.3	1.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.3	0.9	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.3	1.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	3.4	GO:0051787	misfolded protein binding(GO:0051787)
0.3	0.8	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.3	4.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.3	1.8	GO:0046790	virion binding(GO:0046790)
0.3	1.3	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3	3.9	GO:0000146	microfilament motor activity(GO:0000146)
0.3	1.8	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.2	1.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.7	GO:0033142	progesterone receptor binding(GO:0033142)
0.2	2.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	1.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.2	2.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	4.9	GO:0003785	actin monomer binding(GO:0003785)
0.2	1.5	GO:0008517	folic acid transporter activity(GO:0008517)
0.2	1.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.2	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.2	0.7	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	3.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	0.9	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	3.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2	0.9	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2	0.9	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	0.6	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.2	0.6	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.2	3.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.2	0.8	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2	1.0	GO:0004565	beta-galactosidase activity(GO:0004565)
0.2	2.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	0.6	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	1.0	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2	0.6	GO:0070052	collagen V binding(GO:0070052)
0.2	0.4	GO:0016361	activin receptor activity, type I(GO:0016361)
0.2	1.0	GO:0043830	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.2	1.0	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.2	2.1	GO:0008932	lytic endotransglycosylase activity(GO:0008932)
0.2	0.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.2	0.9	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.2	1.9	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2	1.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	2.2	GO:0042608	T cell receptor binding(GO:0042608)
0.2	0.7	GO:0034056	estrogen response element binding(GO:0034056)
0.2	2.5	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	2.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.2	0.5	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.2	0.5	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2	0.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.2	2.7	GO:0008143	poly(A) binding(GO:0008143)
0.2	1.2	GO:0002162	dystroglycan binding(GO:0002162)
0.2	3.0	GO:0017075	syntaxin-1 binding(GO:0017075)
0.2	1.6	GO:0051378	serotonin binding(GO:0051378)
0.2	1.4	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.2	0.3	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2	0.6	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.6	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.4	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.7	GO:0043495	protein anchor(GO:0043495)
0.1	0.6	GO:0031433	telethonin binding(GO:0031433)
0.1	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.7	GO:0032027	myosin light chain binding(GO:0032027)
0.1	0.7	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	0.4	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.4	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1	0.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.7	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	2.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	2.7	GO:0045499	chemorepellent activity(GO:0045499)
0.1	1.0	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.1	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.6	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	0.6	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.1	0.9	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.3	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	0.3	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.3	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	1.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.5	GO:0016936	galactoside binding(GO:0016936)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	1.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.4	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	1.0	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	2.8	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	0.3	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.3	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	1.2	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.7	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.2	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.4	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.3	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	5.2	GO:0019905	syntaxin binding(GO:0019905)
0.1	0.2	GO:0043199	sulfate binding(GO:0043199)
0.1	0.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	2.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.3	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:2001070	starch binding(GO:2001070)
0.1	0.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	2.8	GO:0080131	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.8	GO:0035497	cAMP response element binding(GO:0035497)
0.1	1.6	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	0.9	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1	0.8	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	1.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.7	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.2	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.1	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	0.3	GO:0051434	BH3 domain binding(GO:0051434)
0.1	2.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.4	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.1	0.4	GO:0032052	bile acid binding(GO:0032052)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.5	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.2	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.1	0.1	GO:0032190	acrosin binding(GO:0032190)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.2	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	1.1	GO:0005112	Notch binding(GO:0005112)
0.1	0.6	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.4	GO:0005123	death receptor binding(GO:0005123)
0.1	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.2	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.5	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.3	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	1.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.4	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.2	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	2.0	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.4	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.4	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.2	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	1.3	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.0	0.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	4.0	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.5	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.1	GO:0048045	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.1	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.0	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.2	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.0	GO:0004027	alcohol sulfotransferase activity(GO:0004027)
0.0	0.6	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.3	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0019201	nucleotide kinase activity(GO:0019201)
0.0	0.0	GO:0070061	fructose binding(GO:0070061)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	1.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.6	1.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.6	1.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4	1.7	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.4	0.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	0.7	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.3	10.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	7.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	1.5	PID ATR PATHWAY	ATR signaling pathway
0.2	0.5	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	0.9	PID ALK2 PATHWAY	ALK2 signaling events
0.2	3.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	0.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	4.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	3.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	0.3	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	0.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.7	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	2.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	2.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.5	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	2.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	10.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.6	8.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6	13.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.6	1.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.6	8.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5	20.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.5	5.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.5	3.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.4	3.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.4	4.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.3	1.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.3	13.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	3.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	0.9	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3	0.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.3	4.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	2.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.3	4.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.3	6.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.3	3.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	3.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	3.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	2.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	4.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	3.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.2	2.0	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.2	2.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	1.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	2.7	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.2	1.9	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2	3.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	2.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	0.3	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.1	1.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	1.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	4.1	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.1	1.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	0.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	2.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	2.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	0.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.1	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	3.1	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1	1.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	3.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	0.7	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	0.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.1	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.1	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	1.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	0.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G

Results for En2

Z-value: 2.73

Motif logo

Transcription factors associated with En2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the En2 motif across conditions

Conditions sorted by the z-value of the En2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of En2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: