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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Etv6

Z-value: 2.41

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Transcription factors associated with Etv6

Gene Symbol	Gene ID	Gene Info
Etv6 Ensembl NCBI MGI UniProt	ENSMUSG00000030199.10	ets variant 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_134222360_134222511	Etv6	11165	0.166117	-0.48	2.0e-04	Click!
chr6_134222590_134222917	Etv6	10847	0.166630	-0.40	2.2e-03	Click!
chr6_134262051_134262202	Etv6	14561	0.161313	-0.40	2.2e-03	Click!
chr6_134033112_134033263	Etv6	2513	0.295838	-0.33	1.3e-02	Click!
chr6_134256500_134256651	Etv6	9010	0.168388	-0.33	1.5e-02	Click!

Activity of the Etv6 motif across conditions

Conditions sorted by the z-value of the Etv6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_78861495_78861819	8.98	Atp6v1d	ATPase, H+ transporting, lysosomal V1 subunit D	19	0.67
chr18_62548232_62549066	8.42	Fbxo38	F-box protein 38	35	0.78
chr17_56405416_56405574	6.39	Ptprs	protein tyrosine phosphatase, receptor type, S	8935	0.13
chr14_55671842_55672007	6.07	Gmpr2	guanosine monophosphate reductase 2	17	0.5
chr7_105744333_105744535	6.06	Taf10	TATA-box binding protein associated factor 10	73	0.93
chr10_13008292_13008475	5.97	Sf3b5	splicing factor 3b, subunit 5	3040	0.25
chr8_107056570_107056952	5.97	Cog8	component of oligomeric golgi complex 8	72	0.55
chr12_37241745_37241944	5.96	Agmo	alkylglycerol monooxygenase	16	0.99
chr15_5185671_5186006	5.85	Ttc33	tetratricopeptide repeat domain 33	111	0.49
chr6_7690583_7690734	5.80	Asns	asparagine synthetase	1564	0.43
chr11_117986459_117986961	5.61	Pgs1	phosphatidylglycerophosphate synthase 1	175	0.93
chr7_80947183_80947638	5.60	Sec11a	SEC11 homolog A, signal peptidase complex subunit	101	0.94
chr2_11778402_11778601	5.56	Ankrd16	ankyrin repeat domain 16	10	0.95
chr6_120363997_120364179	5.45	Kdm5a	lysine (K)-specific demethylase 5A	36	0.78
chr12_55155228_55155411	5.39	Srp54b	signal recognition particle 54B	51	0.85
chr11_3451901_3452515	5.36	Rnf185	ring finger protein 185	126	0.53
chr1_58504889_58505222	5.28	Orc2	origin recognition complex, subunit 2	54	0.54
chr4_124802399_124802592	5.26	Mtf1	metal response element binding transcription factor 1	54	0.95
chr2_94010712_94010907	5.26	Alkbh3	alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase	2	0.97
chr12_55230291_55230494	5.20	Srp54c	signal recognition particle 54C	224	0.67
chr2_127208202_127208406	5.16	1810024B03Rik	RIKEN cDNA 1810024B03 gene	24	0.55
chr5_31202209_31202548	5.16	Zfp513	zinc finger protein 513	75	0.92
chr12_55080390_55080577	5.12	Srp54a	signal recognition particle 54A	43	0.84
chr9_19622136_19622591	4.96	Zfp317	zinc finger protein 317	59	0.96
chr5_116024394_116024784	4.95	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	81	0.95
chr13_41000869_41001065	4.90	Pak1ip1	PAK1 interacting protein 1	56	0.67
chr2_132253158_132253669	4.86	AV099323	expressed sequence AV099323	56	0.55
chr14_26669845_26670062	4.67	9930004E17Rik	RIKEN cDNA 9930004E17 gene	57	0.46
chr3_146521363_146521539	4.63	Rpf1	ribosome production factor 1 homolog	22	0.97
chr17_24617516_24617667	4.63	Tsc2	TSC complex subunit 2	3010	0.11
chr17_36271341_36271519	4.51	Trim39	tripartite motif-containing 39	47	0.92
chr2_152226771_152226948	4.48	Csnk2a1	casein kinase 2, alpha 1 polypeptide	17	0.97
chr14_52278918_52280079	4.45	Rab2b	RAB2B, member RAS oncogene family	47	0.51
chr17_21733492_21733782	4.44	Zfp229	zinc finger protein 229	43	0.96
chrX_169320012_169320582	4.42	Hccs	holocytochrome c synthetase	3	0.84
chr18_46741720_46741894	4.32	Ap3s1	adaptor-related protein complex 3, sigma 1 subunit	69	0.71
chr17_20944797_20945472	4.29	Gm49761	predicted gene, 49761	15	0.68
chr2_145934675_145934882	4.26	Cfap61	cilia and flagella associated protein 61	6	0.53
chr7_109082988_109083506	4.24	Ric3	RIC3 acetylcholine receptor chaperone	58	0.97
chr4_125066497_125066766	4.19	Snip1	Smad nuclear interacting protein 1	41	0.93
chr19_5366571_5366780	4.18	Eif1ad	eukaryotic translation initiation factor 1A domain containing	66	0.48
chr11_106255719_106255906	4.16	Ftsj3	FtsJ RNA methyltransferase homolog 3 (E. coli)	8	0.82
chr14_101640358_101640529	4.14	Commd6	COMM domain containing 6	5	0.97
chr19_8871301_8872099	4.14	Ubxn1	UBX domain protein 1	40	0.9
chr2_130667648_130667858	4.12	Itpa	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	52	0.95
chr11_94653662_94653850	4.12	Mrpl27	mitochondrial ribosomal protein L27	11	0.55
chr2_132686675_132687262	4.09	Shld1	shieldin complex subunit 1	37	0.96
chr2_37443118_37443593	4.08	Rabgap1	RAB GTPase activating protein 1	59	0.54
chr14_52197103_52197330	4.07	Supt16	SPT16, facilitates chromatin remodeling subunit	200	0.58
chr5_36830527_36830904	4.04	Man2b2	mannosidase 2, alpha B2	62	0.97
chr11_44529187_44529856	4.02	Rnf145	ring finger protein 145	9216	0.18
chr17_35969652_35970052	3.98	Abcf1	ATP-binding cassette, sub-family F (GCN20), member 1	91	0.89
chr1_179546195_179546570	3.94	Cnst	consortin, connexin sorting protein	12	0.6
chr11_60830808_60831009	3.93	Dhrs7b	dehydrogenase/reductase (SDR family) member 7B	229	0.86
chr17_5286471_5286905	3.92	Gm29050	predicted gene 29050	102075	0.07
chr9_70421744_70422098	3.90	Ccnb2	cyclin B2	374	0.84
chr10_128805324_128805862	3.90	Dnajc14	DnaJ heat shock protein family (Hsp40) member C14	10	0.93
chr1_193173359_193174042	3.84	A130010J15Rik	RIKEN cDNA A130010J15 gene	44	0.95
chr1_167308575_167308778	3.84	Tmco1	transmembrane and coiled-coil domains 1	6	0.96
chr16_56037403_56037620	3.80	Trmt10c	tRNA methyltransferase 10C, mitochondrial RNase P subunit	308	0.79
chr4_137388371_137388553	3.77	2810405F17Rik	RIKEN cDNA 2810405F17 gene	80	0.95
chr3_88424832_88425399	3.71	Slc25a44	solute carrier family 25, member 44	3	0.93
chr2_30967430_30968192	3.68	Tor1a	torsin family 1, member A (torsin A)	61	0.96
chr6_113046036_113046851	3.67	Thumpd3	THUMP domain containing 3	15	0.8
chr15_80097023_80097326	3.65	Syngr1	synaptogyrin 1	696	0.49
chr8_105297551_105298218	3.65	E2f4	E2F transcription factor 4	167	0.83
chr7_127471210_127471989	3.63	Prr14	proline rich 14	109	0.89
chr15_10485915_10486089	3.60	Rad1	RAD1 checkpoint DNA exonuclease	16	0.52
chr15_12824603_12824975	3.60	Drosha	drosha, ribonuclease type III	26	0.63
chr4_115850014_115850176	3.57	Mknk1	MAP kinase-interacting serine/threonine kinase 1	6937	0.13
chr6_125009531_125009725	3.57	Zfp384	zinc finger protein 384	41	0.94
chr6_136828152_136828539	3.55	Wbp11	WW domain binding protein 11	112	0.76
chr2_39007642_39008238	3.52	Arpc5l	actin related protein 2/3 complex, subunit 5-like	136	0.91
chr1_36243812_36244462	3.51	Uggt1	UDP-glucose glycoprotein glucosyltransferase 1	24	0.97
chr6_17797574_17797931	3.49	Gm26738	predicted gene, 26738	37433	0.13
chr15_58933660_58933845	3.47	Ndufb9	NADH:ubiquinone oxidoreductase subunit B9	4	0.49
chr3_157534009_157535172	3.47	Zranb2	zinc finger, RAN-binding domain containing 2	165	0.81
chr2_121473954_121474145	3.39	Mfap1b	microfibrillar-associated protein 1B	18	0.94
chr9_65032072_65032479	3.32	Dpp8	dipeptidylpeptidase 8	139	0.95
chr1_184441391_184441542	3.31	2900092O11Rik	RIKEN cDNA 2900092O11 gene	1514	0.45
chr4_53826161_53826553	3.28	Tmem38b	transmembrane protein 38B	300	0.89
chr15_79670716_79670928	3.28	Tomm22	translocase of outer mitochondrial membrane 22	39	0.94
chr12_100159598_100160070	3.26	Nrde2	nrde-2 necessary for RNA interference, domain containing	181	0.93
chr19_45006351_45006736	3.26	Twnk	twinkle mtDNA helicase	15	0.57
chr2_130424198_130424383	3.25	Pced1a	PC-esterase domain containing 1A	9	0.51
chr15_30610696_30610847	3.20	Gm24487	predicted gene, 24487	9257	0.18
chr2_181319482_181319804	3.19	Rtel1	regulator of telomere elongation helicase 1	96	0.93
chrX_100625656_100626100	3.19	Pdzd11	PDZ domain containing 11	57	0.61
chr8_72570981_72571279	3.17	Smim7	small integral membrane protein 7	42	0.93
chr7_127421975_127422168	3.15	Zfp688	zinc finger protein 688	3	0.93
chr2_26389102_26389724	3.10	Pmpca	peptidase (mitochondrial processing) alpha	57	0.53
chr13_21362676_21363275	3.04	Zscan12	zinc finger and SCAN domain containing 12	143	0.9
chr1_45794842_45795231	3.02	Wdr75	WD repeat domain 75	130	0.95
chr9_20385074_20385289	3.01	Zfp560	zinc finger protein 560	4	0.52
chr15_8109173_8109361	3.01	Nup155	nucleoporin 155	6	0.98
chr17_87025276_87025630	3.01	Pigf	phosphatidylinositol glycan anchor biosynthesis, class F	47	0.55
chr13_36117784_36118119	3.00	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	71	0.86
chr10_83359933_83360353	2.99	D10Wsu102e	DNA segment, Chr 10, Wayne State University 102, expressed	78	0.97
chr12_85110707_85110908	2.98	Dlst	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	26	0.51
chr12_85374188_85374785	2.97	Tmed10	transmembrane p24 trafficking protein 10	204	0.66
chr17_40934490_40934852	2.96	Mmut	methylmalonyl-Coenzyme A mutase	14	0.61
chr11_95011751_95011961	2.94	Samd14	sterile alpha motif domain containing 14	1575	0.24
chr7_126474470_126475241	2.94	Sh2b1	SH2B adaptor protein 1	31	0.95
chr6_35539763_35540120	2.93	Mtpn	myotrophin	53	0.98
chr1_167392688_167392913	2.86	Mgst3	microsomal glutathione S-transferase 3	1041	0.48
chr2_29935294_29935511	2.83	Gle1	GLE1 RNA export mediator (yeast)	24	0.96
chr11_67588922_67589098	2.80	Gas7	growth arrest specific 7	2309	0.33
chr9_37348283_37348681	2.79	Ccdc15	coiled-coil domain containing 15	50	0.95
chr4_31963680_31964247	2.76	Map3k7	mitogen-activated protein kinase kinase kinase 7	134	0.97
chr1_33669479_33669900	2.75	Prim2	DNA primase, p58 subunit	106	0.53
chr2_140066689_140066983	2.75	Tasp1	taspase, threonine aspartase 1	31	0.98
chr6_120822279_120822990	2.75	Atp6v1e1	ATPase, H+ transporting, lysosomal V1 subunit E1	51	0.97
chr10_127290569_127290765	2.72	Gm4189	predicted gene 4189	57	0.54
chr2_11332597_11332748	2.72	Gm37851	predicted gene, 37851	153	0.92
chr11_29526267_29526597	2.70	Mtif2	mitochondrial translational initiation factor 2	4	0.96
chr9_20952766_20953077	2.69	Dnmt1	DNA methyltransferase (cytosine-5) 1	58	0.94
chr4_40948174_40948980	2.69	Chmp5	charged multivesicular body protein 5	170	0.63
chr12_84970815_84970994	2.68	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	4	0.49
chr11_87737188_87737626	2.68	Supt4a	SPT4A, DSIF elongation factor subunit	145	0.91
chr9_79759713_79759940	2.66	Cox7a2	cytochrome c oxidase subunit 7A2	52	0.97
chr8_124520582_124520885	2.66	Cog2	component of oligomeric golgi complex 2	34	0.98
chr11_5485632_5485992	2.65	Gm11962	predicted gene 11962	9634	0.14
chr11_83298909_83299212	2.65	Ap2b1	adaptor-related protein complex 2, beta 1 subunit	36	0.54
chr7_56049865_56050780	2.64	Herc2	HECT and RLD domain containing E3 ubiquitin protein ligase 2	67	0.81
chr4_150568722_150569341	2.62	Gm13091	predicted gene 13091	487	0.51
chr1_161968669_161969306	2.61	4930558K02Rik	RIKEN cDNA 4930558K02 gene	161	0.39
chr13_17993258_17993531	2.60	Yae1d1	Yae1 domain containing 1	45	0.92
chr15_34443090_34443386	2.59	Rpl30	ribosomal protein L30	16	0.77
chr3_95871394_95871675	2.59	C920021L13Rik	RIKEN cDNA C920021L13 gene	3	0.49
chr11_86757222_86757692	2.54	Cltc	clathrin, heavy polypeptide (Hc)	44	0.98
chr15_51865432_51865773	2.54	Eif3h	eukaryotic translation initiation factor 3, subunit H	79	0.97
chr6_149309318_149309909	2.52	Resf1	retroelement silencing factor 1	40	0.97
chr11_114668310_114668676	2.52	Rpl38	ribosomal protein L38	31	0.97
chr11_58330284_58330451	2.50	Zfp672	zinc finger protein 672	28	0.83
chr1_57969978_57970355	2.50	Kctd18	potassium channel tetramerisation domain containing 18	38	0.98
chr18_74267773_74268322	2.50	Mbd1	methyl-CpG binding domain protein 1	128	0.95
chr5_145201828_145202036	2.49	Zkscan14	zinc finger with KRAB and SCAN domains 14	64	0.94
chr16_21332982_21333472	2.48	Magef1	melanoma antigen family F, 1	98	0.97
chr2_12419340_12419682	2.47	Mindy3	MINDY lysine 48 deubiquitinase 3	41	0.97
chr19_32485724_32486055	2.44	Minpp1	multiple inositol polyphosphate histidine phosphatase 1	34	0.49
chr10_14704849_14705669	2.44	Vta1	vesicle (multivesicular body) trafficking 1	200	0.64
chrX_94212852_94213030	2.43	Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	79	0.97
chrX_107816252_107816458	2.42	2610002M06Rik	RIKEN cDNA 2610002M06 gene	21	0.61
chr17_56764467_56764869	2.41	Dus3l	dihydrouridine synthase 3-like (S. cerevisiae)	89	0.94
chr7_66079145_66079708	2.40	Gm45081	predicted gene 45081	47	0.72
chr17_26662965_26663282	2.39	Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	108	0.95
chr11_20914053_20914257	2.39	Gm23681	predicted gene, 23681	23546	0.17
chr19_8770894_8771102	2.38	Tmem223	transmembrane protein 223	2	0.87
chr8_10854830_10855021	2.35	Gm32540	predicted gene, 32540	11261	0.12
chr2_153425549_153426538	2.34	Gm14472	predicted gene 14472	12194	0.16
chr18_75000413_75000592	2.31	Rpl17	ribosomal protein L17	25	0.86
chr11_120457992_120458200	2.30	Ccdc137	coiled-coil domain containing 137	19	0.49
chrX_101287598_101287912	2.28	Med12	mediator complex subunit 12	1731	0.2
chr6_113378048_113378624	2.28	Arpc4	actin related protein 2/3 complex, subunit 4	143	0.76
chr5_142895139_142895334	2.27	Fbxl18	F-box and leucine-rich repeat protein 18	2	0.97
chr10_22730737_22731547	2.26	AC166256.1	novel protein	95	0.67
chr14_51884584_51884965	2.26	Mettl17	methyltransferase like 17	68	0.94
chr3_95855485_95855981	2.25	Prpf3	pre-mRNA processing factor 3	20	0.74
chrX_140956364_140956986	2.23	Psmd10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	14	0.76
chr18_30272681_30273169	2.22	Pik3c3	phosphatidylinositol 3-kinase catalytic subunit type 3	2	0.98
chr11_120624901_120625106	2.20	Sirt7	sirtuin 7	4	0.6
chr10_78247305_78247456	2.20	Trappc10	trafficking protein particle complex 10	2739	0.15
chr3_94886609_94887089	2.17	Psmb4	proteasome (prosome, macropain) subunit, beta type 4	13	0.96
chr10_58255270_58255969	2.16	Gcc2	GRIP and coiled-coil domain containing 2	80	0.96
chr9_20520924_20521753	2.14	Zfp266	zinc finger protein 266	70	0.95
chr18_36783049_36783284	2.13	Hars	histidyl-tRNA synthetase	39	0.51
chr11_16508124_16508749	2.12	Sec61g	SEC61, gamma subunit	48	0.98
chr8_26015514_26015770	2.12	Fnta	farnesyltransferase, CAAX box, alpha	8	0.96
chr17_86301214_86301583	2.12	2010106C02Rik	RIKEN cDNA 2010106C02 gene	14220	0.27
chr6_118419131_118419637	2.11	Bms1	BMS1, ribosome biogenesis factor	20	0.97
chr6_88518714_88519337	2.10	Gm44430	predicted gene, 44430	12	0.61
chr11_77793211_77793566	2.10	Gm10277	predicted gene 10277	5641	0.16
chr10_111972464_111972783	2.09	Krr1	KRR1, small subunit (SSU) processome component, homolog (yeast)	41	0.97
chr13_4190910_4191302	2.09	Akr1c13	aldo-keto reductase family 1, member C13	44	0.96
chr6_128424839_128425024	2.08	Itfg2	integrin alpha FG-GAP repeat containing 2	0	0.94
chr7_127232832_127233741	2.07	Zfp553	zinc finger protein 553	8	0.65
chr1_106796168_106796838	2.06	Vps4b	vacuolar protein sorting 4B	74	0.97
chr10_30600606_30601328	2.06	Trmt11	tRNA methyltransferase 11	218	0.91
chr2_10079825_10080668	2.05	Atp5c1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	70	0.8
chr6_128754257_128754598	2.04	Gm43907	predicted gene, 43907	9783	0.11
chr4_136886113_136886264	2.03	C1qb	complement component 1, q subcomponent, beta polypeptide	1	0.97
chr1_133610228_133610578	2.02	Snrpe	small nuclear ribonucleoprotein E	112	0.95
chr19_38223870_38224599	2.01	Fra10ac1	FRA10AC1 homolog (human)	78	0.97
chr7_12909991_12910417	2.01	Rps5	ribosomal protein S5	12086	0.07
chr13_67525535_67526312	1.96	Zfp87	zinc finger protein 87	198	0.51
chr2_152831597_152831827	1.95	Bcl2l1	BCL2-like 1	2	0.97
chr10_62327332_62327499	1.95	Hk1	hexokinase 1	352	0.86
chr7_67645147_67645521	1.94	Lrrc28	leucine rich repeat containing 28	66	0.96
chr17_33929330_33929641	1.94	Rgl2	ral guanine nucleotide dissociation stimulator-like 2	58	0.88
chr5_24586600_24586907	1.93	Chpf2	chondroitin polymerizing factor 2	3	0.95
chr16_62786657_62787006	1.93	Nsun3	NOL1/NOP2/Sun domain family member 3	13	0.97
chr11_77078150_77078604	1.91	Nsrp1	nuclear speckle regulatory protein 1	58	0.69
chr10_128547748_128547947	1.90	Zc3h10	zinc finger CCCH type containing 10	73	0.89
chr9_107562836_107563301	1.89	Tusc2	tumor suppressor 2, mitochondrial calcium regulator	187	0.8
chr17_35979236_35979423	1.89	Prr3	proline-rich polypeptide 3	30	0.86
chr4_82859084_82859933	1.88	Zdhhc21	zinc finger, DHHC domain containing 21	46	0.98
chr1_190724564_190725420	1.87	Rps6kc1	ribosomal protein S6 kinase polypeptide 1	85471	0.09
chr3_108256684_108257282	1.87	1700010K24Rik	RIKEN cDNA 1700010K24 gene	2	0.52
chr16_91464461_91465455	1.87	A930006K02Rik	RIKEN cDNA A930006K02 gene	67	0.46
chr14_70336335_70336839	1.86	Slc39a14	solute carrier family 39 (zinc transporter), member 14	2389	0.19

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.1	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
1.6	4.9	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.2	3.7	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
1.1	5.5	GO:0046485	ether lipid metabolic process(GO:0046485)
1.1	1.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
1.0	4.1	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
1.0	2.0	GO:0019042	viral latency(GO:0019042)
1.0	2.9	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.9	2.8	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.8	2.5	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.8	2.5	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.8	3.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8	3.9	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.8	2.3	GO:0061511	centriole elongation(GO:0061511)
0.8	3.0	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.8	3.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.8	3.8	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.7	4.3	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.7	2.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.7	2.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.7	2.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.7	2.0	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.6	1.9	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.6	1.9	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.6	5.6	GO:0070365	hepatocyte differentiation(GO:0070365)
0.6	1.7	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.6	1.7	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.6	1.7	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.5	1.6	GO:0030576	Cajal body organization(GO:0030576)
0.5	1.6	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.5	3.3	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.5	2.7	GO:0006449	regulation of translational termination(GO:0006449)
0.5	1.6	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.5	2.6	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.5	6.2	GO:0031167	rRNA methylation(GO:0031167)
0.5	1.5	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.5	7.0	GO:0006465	signal peptide processing(GO:0006465)
0.5	3.0	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.5	2.5	GO:0006528	asparagine metabolic process(GO:0006528)
0.5	1.5	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.5	1.9	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.5	4.2	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.5	1.4	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.5	5.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.5	0.9	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.4	3.5	GO:0006013	mannose metabolic process(GO:0006013)
0.4	0.9	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4	1.3	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4	2.5	GO:0031053	primary miRNA processing(GO:0031053)
0.4	1.3	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.4	1.6	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.4	1.9	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4	5.9	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.4	1.4	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.4	1.4	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3	1.0	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.3	1.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.3	8.9	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.3	1.6	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3	1.0	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3	2.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3	1.0	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3	0.9	GO:0019086	late viral transcription(GO:0019086)
0.3	1.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.3	1.9	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.3	1.2	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.3	2.2	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.3	1.2	GO:0061724	lipophagy(GO:0061724)
0.3	4.9	GO:0046686	response to cadmium ion(GO:0046686)
0.3	3.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.3	1.2	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3	1.2	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.3	0.9	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.3	1.4	GO:0072675	osteoclast fusion(GO:0072675)
0.3	1.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.3	0.8	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3	0.8	GO:0009826	unidimensional cell growth(GO:0009826)
0.3	0.8	GO:0042117	monocyte activation(GO:0042117)
0.3	0.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.3	1.5	GO:0061620	glycolytic process through glucose-6-phosphate(GO:0061620)
0.3	0.8	GO:0007228	positive regulation of hh target transcription factor activity(GO:0007228)
0.2	2.4	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2	3.6	GO:0030488	tRNA methylation(GO:0030488)
0.2	3.1	GO:0045116	protein neddylation(GO:0045116)
0.2	0.7	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	0.7	GO:0046075	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.2	1.6	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.2	1.5	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	0.6	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2	6.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2	1.2	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.2	2.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.2	0.8	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.2	0.8	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.2	3.1	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	0.8	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2	1.9	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
0.2	0.7	GO:0072697	protein localization to cell cortex(GO:0072697)
0.2	1.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2	0.5	GO:0046104	thymidine metabolic process(GO:0046104)
0.2	0.9	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.2	1.4	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2	0.4	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.2	0.5	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	6.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.2	0.7	GO:0046655	folic acid metabolic process(GO:0046655)
0.2	0.5	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.2	2.6	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.2	1.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	0.5	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2	5.6	GO:0061512	protein localization to cilium(GO:0061512)
0.2	1.2	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2	0.8	GO:0021764	amygdala development(GO:0021764)
0.2	4.9	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2	0.6	GO:0008228	opsonization(GO:0008228)
0.2	2.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2	0.6	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.2	2.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2	2.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	0.3	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.2	4.7	GO:0045841	negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.1	0.9	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.9	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	3.5	GO:0042255	ribosome assembly(GO:0042255)
0.1	0.4	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	1.7	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1	0.5	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	1.3	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.1	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	1.3	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.3	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	1.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.9	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.6	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	1.1	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	2.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	5.7	GO:0032543	mitochondrial translation(GO:0032543)
0.1	0.5	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1	0.6	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	0.3	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	1.4	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.4	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	1.1	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	0.3	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	4.5	GO:0034394	protein localization to cell surface(GO:0034394)
0.1	1.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	1.0	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.1	0.3	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.1	0.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	5.5	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1	1.5	GO:0006734	NADH metabolic process(GO:0006734)
0.1	0.4	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.5	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1	0.5	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	1.3	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.1	0.6	GO:0043320	natural killer cell degranulation(GO:0043320)
0.1	0.5	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.5	GO:0023035	CD40 signaling pathway(GO:0023035)
0.1	2.0	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1	1.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	0.7	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	1.3	GO:0035357	peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.1	2.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	1.1	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.1	0.5	GO:0006477	protein sulfation(GO:0006477)
0.1	0.4	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1	1.6	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	1.8	GO:0006308	DNA catabolic process(GO:0006308)
0.1	0.2	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1	1.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.1	GO:0002432	granuloma formation(GO:0002432)
0.1	0.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.6	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.1	0.4	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	0.2	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1	0.2	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.2	GO:0000710	meiotic mismatch repair(GO:0000710)
0.1	5.5	GO:0006413	translational initiation(GO:0006413)
0.1	3.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.1	3.0	GO:0048538	thymus development(GO:0048538)
0.1	1.0	GO:0055070	copper ion homeostasis(GO:0055070)
0.1	0.2	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	2.7	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.1	0.1	GO:0043096	purine nucleobase salvage(GO:0043096)
0.1	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.1	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.1	0.3	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.6	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1	0.3	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.1	2.1	GO:0051310	metaphase plate congression(GO:0051310)
0.1	0.5	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.5	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	3.3	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1	0.3	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1	0.9	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	1.0	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	0.6	GO:0046415	urate metabolic process(GO:0046415)
0.1	6.7	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.1	0.6	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	0.3	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	2.0	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	0.6	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.3	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	2.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.1	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.4	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1	0.2	GO:0070589	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.1	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.3	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.1	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1	0.5	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.5	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.1	0.4	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.7	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	0.7	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.2	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.1	0.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	1.0	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0	0.2	GO:0006598	polyamine catabolic process(GO:0006598)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	1.2	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.6	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	1.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.4	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.3	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	1.0	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.2	GO:0032570	response to progesterone(GO:0032570)
0.0	0.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	4.0	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.5	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.0	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	3.5	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.3	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.3	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	3.3	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.6	GO:0006829	zinc II ion transport(GO:0006829)
0.0	1.2	GO:0035904	aorta development(GO:0035904)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	1.9	GO:0008033	tRNA processing(GO:0008033)
0.0	0.1	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0	6.2	GO:0006260	DNA replication(GO:0006260)
0.0	0.2	GO:0030953	astral microtubule organization(GO:0030953)
0.0	2.8	GO:0016573	histone acetylation(GO:0016573)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.0	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.0	2.2	GO:0060021	palate development(GO:0060021)
0.0	0.1	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	1.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	1.2	GO:0071466	cellular response to xenobiotic stimulus(GO:0071466)
0.0	0.1	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.2	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.1	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.0	GO:2000520	regulation of immunological synapse formation(GO:2000520)
0.0	0.2	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.2	GO:0015865	purine nucleotide transport(GO:0015865)
0.0	0.0	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.0	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0	0.3	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.2	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	1.0	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.0	0.0	GO:0042738	biphenyl metabolic process(GO:0018879) exogenous drug catabolic process(GO:0042738)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.3	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.5	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.3	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.0	GO:2000977	regulation of forebrain neuron differentiation(GO:2000977) negative regulation of forebrain neuron differentiation(GO:2000978)
0.0	0.0	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0030049	muscle filament sliding(GO:0030049)
0.0	0.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.3	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.0	0.1	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.0	GO:0033047	regulation of mitotic sister chromatid segregation(GO:0033047)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	0.1	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:2000316	regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.5	GO:0001947	heart looping(GO:0001947)
0.0	0.0	GO:0031049	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	1.9	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.0	2.1	GO:0050714	positive regulation of protein secretion(GO:0050714)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.3	GO:0032611	interleukin-1 beta production(GO:0032611)
0.0	0.0	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.0	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0072674	multinuclear osteoclast differentiation(GO:0072674)
0.0	0.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.0	GO:1901525	regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0	0.0	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.0	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0070268	cornification(GO:0070268)
0.0	0.0	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.4	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.0	0.5	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0030813	positive regulation of nucleotide catabolic process(GO:0030813)
0.0	0.8	GO:0007338	single fertilization(GO:0007338)
0.0	0.0	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.0	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.0	GO:0050904	diapedesis(GO:0050904)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.9	GO:0051168	nuclear export(GO:0051168)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0	0.0	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.6	GO:0000125	PCAF complex(GO:0000125)
1.3	2.7	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
1.3	3.9	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.3	8.9	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
1.0	2.9	GO:0044611	nuclear pore inner ring(GO:0044611)
0.9	2.8	GO:0097451	glial limiting end-foot(GO:0097451)
0.9	2.7	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.8	2.5	GO:0031523	Myb complex(GO:0031523)
0.8	5.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.7	3.5	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.7	4.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.7	2.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.5	1.6	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.5	3.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5	5.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.5	5.8	GO:0017119	Golgi transport complex(GO:0017119)
0.5	1.9	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.5	1.4	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.5	0.9	GO:0097441	basilar dendrite(GO:0097441)
0.5	3.6	GO:0042788	polysomal ribosome(GO:0042788)
0.4	3.1	GO:1904115	axon cytoplasm(GO:1904115)
0.4	4.3	GO:0005687	U4 snRNP(GO:0005687)
0.4	4.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.4	2.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4	1.9	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.4	1.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.4	1.9	GO:0030896	checkpoint clamp complex(GO:0030896)
0.4	3.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.4	1.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.4	2.8	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	1.7	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.3	2.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.3	3.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.3	7.3	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.3	3.5	GO:0001527	microfibril(GO:0001527)
0.3	2.5	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3	2.8	GO:0000124	SAGA complex(GO:0000124)
0.3	0.9	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.3	1.2	GO:0070876	SOSS complex(GO:0070876)
0.3	2.0	GO:0090543	Flemming body(GO:0090543)
0.3	1.9	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.3	1.1	GO:0071797	LUBAC complex(GO:0071797)
0.3	2.4	GO:0005682	U5 snRNP(GO:0005682)
0.3	0.8	GO:0097543	ciliary inversin compartment(GO:0097543)
0.3	6.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.2	1.5	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.2	1.2	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2	0.9	GO:1990130	Iml1 complex(GO:1990130)
0.2	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	1.5	GO:0033263	CORVET complex(GO:0033263)
0.2	0.8	GO:0072487	MSL complex(GO:0072487)
0.2	2.4	GO:0005721	pericentric heterochromatin(GO:0005721)
0.2	2.7	GO:0031011	Ino80 complex(GO:0031011)
0.2	2.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	6.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	1.1	GO:0042587	glycogen granule(GO:0042587)
0.2	2.0	GO:0005652	nuclear lamina(GO:0005652)
0.2	0.9	GO:0034709	methylosome(GO:0034709)
0.2	0.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	0.6	GO:0035363	histone locus body(GO:0035363)
0.2	1.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	0.9	GO:0070847	core mediator complex(GO:0070847)
0.2	1.6	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.2	2.9	GO:0005839	proteasome core complex(GO:0005839)
0.1	1.7	GO:0000800	lateral element(GO:0000800)
0.1	0.4	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.7	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.4	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	5.2	GO:0030684	preribosome(GO:0030684)
0.1	5.6	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	4.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.5	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.1	0.4	GO:0035061	interchromatin granule(GO:0035061)
0.1	1.2	GO:0042555	MCM complex(GO:0042555)
0.1	0.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1	0.7	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.1	0.5	GO:0042825	TAP complex(GO:0042825)
0.1	0.3	GO:0005745	m-AAA complex(GO:0005745)
0.1	0.8	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	1.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	1.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	2.1	GO:1902555	endoribonuclease complex(GO:1902555)
0.1	0.3	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.5	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.8	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	0.7	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.3	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	1.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	1.0	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.1	3.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	0.3	GO:0032437	cuticular plate(GO:0032437)
0.1	2.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	0.3	GO:0070069	cytochrome complex(GO:0070069)
0.1	1.6	GO:0097228	sperm principal piece(GO:0097228)
0.1	1.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	0.4	GO:0042382	paraspeckles(GO:0042382)
0.1	0.9	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	0.8	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	4.7	GO:1990204	oxidoreductase complex(GO:1990204)
0.1	0.4	GO:0071439	clathrin complex(GO:0071439)
0.1	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	2.2	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.1	0.3	GO:0097342	ripoptosome(GO:0097342)
0.1	1.3	GO:0030894	replisome(GO:0030894)
0.1	0.9	GO:0015030	Cajal body(GO:0015030)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.1	GO:0071817	MMXD complex(GO:0071817)
0.1	3.0	GO:0016363	nuclear matrix(GO:0016363)
0.1	1.9	GO:0044452	nucleolar part(GO:0044452)
0.1	0.5	GO:0097542	ciliary tip(GO:0097542)
0.1	1.7	GO:0031672	A band(GO:0031672)
0.0	0.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.7	GO:0005795	Golgi stack(GO:0005795)
0.0	0.2	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.4	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.7	GO:0000145	exocyst(GO:0000145)
0.0	0.7	GO:0002102	podosome(GO:0002102)
0.0	4.8	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.2	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.5	GO:0001891	phagocytic cup(GO:0001891)
0.0	1.1	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.3	GO:0030118	clathrin coat(GO:0030118)
0.0	9.6	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.7	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	2.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	38.5	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	1.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.3	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0070938	contractile ring(GO:0070938)
0.0	0.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	3.4	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.6	GO:0031201	SNARE complex(GO:0031201)
0.0	24.7	GO:0005739	mitochondrion(GO:0005739)
0.0	0.4	GO:0030904	retromer complex(GO:0030904)
0.0	2.8	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.0	GO:0097433	dense body(GO:0097433)
0.0	0.0	GO:0044299	C-fiber(GO:0044299)
0.0	1.9	GO:0072562	blood microparticle(GO:0072562)
0.0	1.8	GO:0012506	vesicle membrane(GO:0012506)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	3.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	5.1	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.0	GO:0061574	ASAP complex(GO:0061574)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.0	GO:0072534	perineuronal net(GO:0072534)
0.0	0.2	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.9	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.0	GO:0046930	membrane attack complex(GO:0005579) pore complex(GO:0046930)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.0	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.0	GO:0005833	hemoglobin complex(GO:0005833)
0.0	15.2	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0044815	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0	0.7	GO:0030141	secretory granule(GO:0030141)
0.0	0.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	8.9	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
1.7	5.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
1.1	4.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
1.1	5.5	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.9	3.7	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.8	5.9	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.8	2.4	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.8	3.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.7	2.2	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.7	2.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.6	3.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.6	2.5	GO:0032051	clathrin light chain binding(GO:0032051)
0.5	1.6	GO:0032357	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.5	2.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.5	2.0	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.5	2.4	GO:0071253	connexin binding(GO:0071253)
0.5	1.4	GO:0030621	U4 snRNA binding(GO:0030621)
0.5	1.9	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.5	1.9	GO:0051434	BH3 domain binding(GO:0051434)
0.4	4.8	GO:0070182	DNA polymerase binding(GO:0070182)
0.4	1.3	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.4	3.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.4	2.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	2.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.4	3.5	GO:0034522	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.4	3.9	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4	1.5	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4	1.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.4	1.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4	3.9	GO:0051787	misfolded protein binding(GO:0051787)
0.4	2.8	GO:1990446	U1 snRNP binding(GO:1990446)
0.4	4.6	GO:0036222	XTP diphosphatase activity(GO:0036222)
0.3	2.6	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.3	4.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.3	5.9	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3	3.1	GO:0015266	protein channel activity(GO:0015266)
0.3	0.9	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3	2.7	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.3	3.0	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.3	1.1	GO:0098821	BMP receptor activity(GO:0098821)
0.3	3.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.3	5.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	3.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.3	12.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.3	1.3	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.3	0.8	GO:0004946	bombesin receptor activity(GO:0004946)
0.2	1.2	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.2	1.5	GO:0052630	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.2	1.4	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.2	3.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	2.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2	0.9	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.2	0.7	GO:0051870	methotrexate binding(GO:0051870)
0.2	3.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	2.1	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2	4.0	GO:0052769	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.2	6.6	GO:0070063	RNA polymerase binding(GO:0070063)
0.2	1.2	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.2	1.2	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.2	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	3.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	0.6	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2	0.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	0.8	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.2	0.6	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2	5.2	GO:0034792	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.2	0.3	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2	4.6	GO:0031369	translation initiation factor binding(GO:0031369)
0.2	0.8	GO:0070728	leucine binding(GO:0070728)
0.2	1.2	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2	2.3	GO:0032183	SUMO binding(GO:0032183)
0.2	0.8	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2	1.1	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.2	0.6	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.2	4.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	1.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2	1.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2	0.5	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2	0.9	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	3.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	11.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	2.1	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.3	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.5	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	0.7	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	5.3	GO:0043022	ribosome binding(GO:0043022)
0.1	0.4	GO:0004103	choline kinase activity(GO:0004103)
0.1	1.7	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	0.5	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.6	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.1	3.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.9	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.4	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.5	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.6	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	3.6	GO:0016751	S-succinyltransferase activity(GO:0016751)
0.1	0.8	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.9	GO:0051400	BH domain binding(GO:0051400)
0.1	5.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	1.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.6	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	7.7	GO:0008565	protein transporter activity(GO:0008565)
0.1	0.6	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	8.0	GO:0015405	primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	1.3	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.4	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.2	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.1	0.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	6.2	GO:0008013	beta-catenin binding(GO:0008013)
0.1	2.1	GO:0004495	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1	0.2	GO:1904680	oligopeptide transmembrane transporter activity(GO:0035673) peptide transmembrane transporter activity(GO:1904680)
0.1	1.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.7	GO:0043531	ADP binding(GO:0043531)
0.1	1.8	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	4.6	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.7	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.2	GO:0019976	interleukin-2 binding(GO:0019976)
0.1	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.6	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1	1.1	GO:0005521	lamin binding(GO:0005521)
0.1	2.6	GO:0035591	signaling adaptor activity(GO:0035591)
0.1	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	4.3	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1	0.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	0.3	GO:0032404	mismatch repair complex binding(GO:0032404)
0.1	0.3	GO:0015197	peptide transporter activity(GO:0015197)
0.1	3.5	GO:0003724	RNA helicase activity(GO:0003724)
0.1	0.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.4	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	5.8	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	1.0	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.2	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.1	0.5	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	0.2	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	5.0	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.2	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	1.8	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.4	GO:0004568	chitinase activity(GO:0004568)
0.0	1.4	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.4	GO:0070402	NADPH binding(GO:0070402)
0.0	8.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.7	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.8	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	1.6	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.8	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	1.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.5	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	8.4	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	1.0	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.6	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	1.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.6	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	2.6	GO:0000149	SNARE binding(GO:0000149)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	1.0	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.5	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	4.4	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.3	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.7	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.1	GO:0019002	GMP binding(GO:0019002)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	2.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	1.1	GO:0004386	helicase activity(GO:0004386)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	4.8	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	17.2	GO:0044822	poly(A) RNA binding(GO:0044822)
0.0	1.0	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.1	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.7	GO:0052767	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	1.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.3	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	2.1	GO:0005267	potassium channel activity(GO:0005267)
0.0	0.1	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.3	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	1.4	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.9	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.3	GO:0019825	oxygen binding(GO:0019825)
0.0	0.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743) methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	1.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.6	GO:0051087	chaperone binding(GO:0051087)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	1.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	3.7	GO:0005525	GTP binding(GO:0005525)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	2.3	GO:0003779	actin binding(GO:0003779)
0.0	0.0	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.0	GO:0015928	fucosidase activity(GO:0015928)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.0	GO:0003916	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.9	PID MYC PATHWAY	C-MYC pathway
0.3	0.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.3	3.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	4.0	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	3.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	2.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	1.9	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	5.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	6.7	PID LKB1 PATHWAY	LKB1 signaling events
0.2	3.7	PID BARD1 PATHWAY	BARD1 signaling events
0.1	0.9	PID AURORA A PATHWAY	Aurora A signaling
0.1	3.2	PID ATR PATHWAY	ATR signaling pathway
0.1	3.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	4.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	1.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	2.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	1.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	3.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	1.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	0.8	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	2.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.0	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.7	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.6	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	2.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	2.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4	5.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4	4.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4	2.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.4	7.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	4.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.3	7.9	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.3	2.0	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.3	2.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.3	3.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.3	3.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3	2.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3	2.9	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.3	3.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	2.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	2.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	2.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	1.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.2	1.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	3.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.2	8.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.2	3.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	3.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	5.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	6.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	3.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	1.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	1.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	2.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	1.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	0.7	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	3.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.9	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.5	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	4.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	0.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	0.9	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	4.3	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.1	1.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	2.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	1.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	5.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.1	1.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	1.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	3.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	1.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	1.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.6	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.7	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.2	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	5.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	1.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.0	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	Genes involved in Post-translational protein modification
0.0	0.0	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers

Results for Etv6

Z-value: 2.41

Motif logo

Transcription factors associated with Etv6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Etv6 motif across conditions

Conditions sorted by the z-value of the Etv6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: