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ENCODE: ATAC-seq of different tissues during embryonic development
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Results for Figla

Z-value: 1.44

Motif logo

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Transcription factors associated with Figla

Gene Symbol Gene ID Gene Info
Figla
ENSMUSG00000030001.3 folliculogenesis specific basic helix-loop-helix

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_86014884_86015035Figla12120.309814-0.482.3e-04Click!

Activity of the Figla motif across conditions

Conditions sorted by the z-value of the Figla motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_81913328_81913479 3.81 Gm7516
 predicted gene 7516
 116162
 0.06
chr9_45000362_45000513 3.29 Gm48719
 predicted gene, 48719
 1008
 0.29
chr13_94573935_94574086 2.94 Ap3b1
 adaptor-related protein complex 3, beta 1 subunit
 31707
 0.15
chr3_101831618_101831892 2.94 Mab21l3
 mab-21-like 3
 4468
 0.25
chrX_50732185_50732585 2.87 Firre
 functional intergenic repeating RNA element
 97064
 0.08
chr7_38125569_38125739 2.84 Ccne1
 cyclin E1
 18120
 0.14
chr1_90093233_90093384 2.82 Iqca
 IQ motif containing with AAA domain
 3164
 0.29
chr1_162281969_162282294 2.80 Dnm3
 dynamin 3
 13449
 0.18
chr10_22591845_22591996 2.76 Slc2a12
 solute carrier family 2 (facilitated glucose transporter), member 12
 53091
 0.12
chr4_123000651_123001088 2.73 Mycl
 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
 1530
 0.32
chr3_81025915_81026237 2.69 Gm42476
 predicted gene 42476
 6878
 0.16
chr7_62269572_62269723 2.65 Gm9801
 predicted gene 9801
 60168
 0.11
chr7_136214095_136214250 2.64 Gm36737
 predicted gene, 36737
 40876
 0.16
chr7_75955628_75955968 2.58 Gm45139
 predicted gene 45139
 45026
 0.16
chr3_35253995_35254146 2.55 1700017M07Rik
 RIKEN cDNA 1700017M07 gene
 22061
 0.24
chr7_70644076_70644276 2.34 Gm44808
 predicted gene 44808
 5566
 0.21
chr7_83459673_83459824 2.26 Gm44991
 predicted gene 44991
 11960
 0.19
chr18_61827328_61827479 2.19 Afap1l1
 actin filament associated protein 1-like 1
 40701
 0.13
chr11_7409190_7409341 2.19 Gm11986
 predicted gene 11986
 118891
 0.06
chr10_71292265_71292619 2.17 Gm34376
 predicted gene, 34376
 4713
 0.14
chr3_87949249_87949414 2.16 Crabp2
 cellular retinoic acid binding protein II
 665
 0.5
chr18_69614138_69614719 2.15 Tcf4
 transcription factor 4
 1984
 0.45
chrX_100356881_100357032 2.14 Gm14828
 predicted gene 14828
 19442
 0.13
chr1_37045616_37045767 2.13 Vwa3b
 von Willebrand factor A domain containing 3B
 9983
 0.19
chr10_57040297_57040501 2.12 Gm36827
 predicted gene, 36827
 58167
 0.13
chr8_108672020_108672182 2.06 Zfhx3
 zinc finger homeobox 3
 30999
 0.2
chr6_100380681_100380861 2.05 Rybp
 RING1 and YY1 binding protein
 93286
 0.06
chr2_163675221_163675602 2.05 Pkig
 protein kinase inhibitor, gamma
 13912
 0.13
chr18_81830833_81831208 2.04 Gm30454
 predicted gene, 30454
 18996
 0.19
chr10_69583868_69584467 1.99 Gm46231
 predicted gene, 46231
 17806
 0.24
chr10_25708049_25708282 1.97 Gm36543
 predicted gene, 36543
 222
 0.95
chr14_7567758_7569131 1.93 Gm3558
 predicted gene 3558
 122
 0.95
chr9_121072512_121072663 1.93 Ulk4
 unc-51-like kinase 4
 27655
 0.18
chr16_20619519_20619670 1.93 Camk2n2
 calcium/calmodulin-dependent protein kinase II inhibitor 2
 1693
 0.13
chr2_152718107_152718461 1.91 Id1
 inhibitor of DNA binding 1, HLH protein
 17967
 0.09
chr6_100732315_100732977 1.91 Gm15576
 predicted gene 15576
 6412
 0.18
chr3_139861125_139861433 1.91 Gm43678
 predicted gene 43678
 48515
 0.17
chr2_180362989_180363283 1.90 B230312C02Rik
 RIKEN cDNA B230312C02 gene
 22749
 0.1
chr3_134330902_134331053 1.89 Gm43558
 predicted gene 43558
 26315
 0.15
chr1_118825166_118825848 1.88 Gm28467
 predicted gene 28467
 15371
 0.24
chr12_13706665_13706816 1.87 Gm35890
 predicted gene, 35890
 37887
 0.13
chr18_32442052_32442203 1.86 Bin1
 bridging integrator 1
 14093
 0.15
chr17_59955724_59955911 1.81 Gm49853
 predicted gene, 49853
 100600
 0.08
chr10_22271501_22271686 1.79 H60b
 histocompatibility 60b
 1753
 0.22
chr4_64143175_64143326 1.75 8030451A03Rik
 RIKEN cDNA 8030451A03 gene
 5303
 0.28
chr9_74912723_74912874 1.75 Fam214a
 family with sequence similarity 214, member A
 40086
 0.12
chr12_91786386_91786707 1.72 Ston2
 stonin 2
 110
 0.96
chr13_3712791_3713218 1.66 Gm47695
 predicted gene, 47695
 46821
 0.1
chr10_22461497_22461758 1.64 Gm26585
 predicted gene, 26585
 8107
 0.2
chr9_32720264_32720442 1.61 Gm27240
 predicted gene 27240
 9182
 0.19
chr5_46022114_46022265 1.60 4930405L22Rik
 RIKEN cDNA 4930405L22 gene
 89780
 0.09
chr6_107708405_107708573 1.58 4933431M02Rik
 RIKEN cDNA 4933431M02 gene
 80715
 0.1
chrX_105763292_105763443 1.58 Fgf16
 fibroblast growth factor 16
 912
 0.54
chr2_91904646_91904972 1.57 Gm10805
 predicted gene 10805
 16119
 0.12
chr14_78204129_78204297 1.55 Gm48959
 predicted gene, 48959
 4840
 0.2
chr5_19907703_19908339 1.54 Magi2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 60
 0.99
chr14_4181957_4182899 1.54 Gm2974
 predicted gene 2974
 148
 0.94
chr7_72704041_72704213 1.50 Gm7693
 predicted gene 7693
 9494
 0.18
chr16_63084175_63084358 1.50 Gm49621
 predicted gene, 49621
 27424
 0.22
chr14_117826490_117826737 1.48 Mir6239
 microRNA 6239
 127234
 0.05
chr2_59417528_59417679 1.47 Gm13549
 predicted gene 13549
 17822
 0.16
chr5_45444259_45444410 1.47 Qdpr
 quinoid dihydropteridine reductase
 225
 0.9
chr13_98591388_98591693 1.46 Gm4815
 predicted gene 4815
 21961
 0.11
chr14_122483827_122483978 1.46 Zic2
 zinc finger protein of the cerebellum 2
 5802
 0.11
chr5_37797365_37797516 1.45 Gm43763
 predicted gene 43763
 9866
 0.2
chr8_70476397_70477967 1.45 Klhl26
 kelch-like 26
 214
 0.86
chr6_33874720_33874928 1.45 Exoc4
 exocyst complex component 4
 12724
 0.27
chr8_82970052_82970399 1.41 Gm18212
 predicted gene, 18212
 17713
 0.23
chr4_95584440_95584591 1.41 Fggy
 FGGY carbohydrate kinase domain containing
 729
 0.7
chr18_35362758_35362909 1.40 Sil1
 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
 19766
 0.18
chr16_15052910_15053386 1.40 Gm49536
 predicted gene, 49536
 52826
 0.14
chr7_51627192_51627643 1.39 Slc17a6
 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
 2063
 0.32
chr9_118988700_118988851 1.39 Mir26a-1
 microRNA 26a-1
 43021
 0.1
chr17_56974816_56974970 1.37 Acer1
 alkaline ceramidase 1
 7233
 0.08
chr7_143253195_143253397 1.36 Kcnq1ot1
 KCNQ1 overlapping transcript 1
 43253
 0.1
chr6_94987515_94987673 1.35 4930511E03Rik
 RIKEN cDNA 4930511E03 gene
 43760
 0.16
chr10_125954960_125955140 1.35 Lrig3
 leucine-rich repeats and immunoglobulin-like domains 3
 11118
 0.29
chr14_3208167_3209194 1.34 D830030K20Rik
 RIKEN cDNA D830030K20 gene
 103
 0.95
chr19_7083550_7083737 1.34 AC109619.1
 novel transcript, antisense to Macrod1
 4778
 0.13
chr13_113294073_113294359 1.34 BC067074
 cDNA sequence BC067074
 1057
 0.55
chr11_61675416_61675590 1.34 Grap
 GRB2-related adaptor protein
 6457
 0.17
chr2_100865612_100865778 1.32 Gm13810
 predicted gene 13810
 237652
 0.02
chr3_141897285_141897436 1.32 Bmpr1b
 bone morphogenetic protein receptor, type 1B
 34148
 0.22
chr11_89856338_89856636 1.30 Ankfn1
 ankyrin-repeat and fibronectin type III domain containing 1
 15221
 0.28
chr1_84694763_84694961 1.30 Mir5126
 microRNA 5126
 977
 0.39
chr17_56147575_56147726 1.28 Sema6b
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 7307
 0.09
chr15_7193540_7193868 1.28 Egflam
 EGF-like, fibronectin type III and laminin G domains
 29365
 0.2
chr7_121011950_121012101 1.27 Gm9234
 predicted pseudogene 9234
 3608
 0.11
chr13_25750573_25750742 1.27 Gm11350
 predicted gene 11350
 69514
 0.13
chr6_51715653_51715804 1.27 Gm38811
 predicted gene, 38811
 4647
 0.29
chr15_86264510_86264661 1.26 Tbc1d22a
 TBC1 domain family, member 22a
 29080
 0.18
chr10_80913997_80914464 1.26 Lmnb2
 lamin B2
 3621
 0.11
chr5_32713265_32714499 1.26 Gm43852
 predicted gene 43852
 106
 0.94
chr16_89531028_89531179 1.25 Krtap7-1
 keratin associated protein 7-1
 22780
 0.15
chr13_104576302_104576687 1.25 2610204G07Rik
 RIKEN cDNA 2610204G07 gene
 108437
 0.07
chr4_57958213_57958364 1.25 Txn1
 thioredoxin 1
 1877
 0.36
chr12_79782713_79783051 1.24 9430078K24Rik
 RIKEN cDNA 9430078K24 gene
 141851
 0.04
chr13_62865679_62865981 1.24 Fbp1
 fructose bisphosphatase 1
 6928
 0.13
chr3_128369618_128369891 1.23 Gm43656
 predicted gene 43656
 88663
 0.09
chr3_120570837_120570994 1.20 Gm25013
 predicted gene, 25013
 39178
 0.22
chr13_48154741_48154892 1.19 Gm36346
 predicted gene, 36346
 82435
 0.07
chr14_21498538_21498796 1.19 Kat6b
 K(lysine) acetyltransferase 6B
 1103
 0.54
chr7_136366004_136366196 1.19 Gm36849
 predicted gene, 36849
 12736
 0.21
chr13_56160173_56160324 1.17 Gm25148
 predicted gene, 25148
 7352
 0.16
chr15_35849536_35849687 1.17 Gm48965
 predicted gene, 48965
 5783
 0.17
chr10_78464271_78465733 1.16 Pdxk
 pyridoxal (pyridoxine, vitamin B6) kinase
 27
 0.93
chr10_119075144_119075295 1.16 Gm18904
 predicted gene, 18904
 15123
 0.14
chr8_61273669_61273862 1.16 1700001D01Rik
 RIKEN cDNA 1700001D01 gene
 15107
 0.2
chr10_99116027_99116178 1.16 Galnt4
 polypeptide N-acetylgalactosaminyltransferase 4
 7943
 0.13
chr2_102544257_102544426 1.15 Pamr1
 peptidase domain containing associated with muscle regeneration 1
 5671
 0.29
chr2_152091633_152091835 1.14 Scrt2
 scratch family zinc finger 2
 10205
 0.13
chr2_126932364_126933545 1.14 Sppl2a
 signal peptide peptidase like 2A
 281
 0.9
chr10_115107774_115107925 1.14 Tph2
 tryptophan hydroxylase 2
 67709
 0.11
chr16_15114704_15114855 1.14 Gm7731
 predicted gene 7731
 102549
 0.06
chr14_22651376_22651530 1.14 Lrmda
 leucine rich melanocyte differentiation associated
 54940
 0.15
chr18_58065249_58065400 1.14 Fbn2
 fibrillin 2
 25653
 0.25
chr16_49319411_49319604 1.14 Gm5407
 predicted gene 5407
 21609
 0.2
chr15_27967230_27967381 1.13 Trio
 triple functional domain (PTPRF interacting)
 28058
 0.19
chr5_135513193_135513444 1.12 Hip1
 huntingtin interacting protein 1
 24060
 0.12
chr12_108215060_108215478 1.11 Ccnk
 cyclin K
 16184
 0.19
chr8_12051470_12051621 1.10 B020031H02Rik
 RIKEN cDNA B020031H02 gene
 103206
 0.06
chr5_36373145_36373857 1.09 Sorcs2
 sortilin-related VPS10 domain containing receptor 2
 7583
 0.22
chr4_138892745_138892896 1.09 Pla2g2e
 phospholipase A2, group IIE
 13460
 0.12
chr4_111452121_111452592 1.08 Bend5
 BEN domain containing 5
 19037
 0.21
chr1_84990555_84991042 1.08 Gm29284
 predicted gene 29284
 2234
 0.19
chr6_127011987_127012359 1.07 Fgf6
 fibroblast growth factor 6
 3413
 0.16
chr15_56764893_56765168 1.07 Has2os
 hyaluronan synthase 2, opposite strand
 430
 0.87
chr8_123137604_123137977 1.06 Mir7080
 microRNA 7080
 7684
 0.08
chr1_134245463_134245637 1.06 Adora1
 adenosine A1 receptor
 10119
 0.14
chr16_94246289_94246440 1.05 Hlcs
 holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
 279
 0.87
chr2_136712228_136712733 1.05 Snap25
 synaptosomal-associated protein 25
 973
 0.59
chr15_55213721_55213872 1.05 Gm26296
 predicted gene, 26296
 48807
 0.13
chr12_73460617_73460768 1.05 Gm48656
 predicted gene, 48656
 3785
 0.2
chr19_32601462_32601622 1.05 Papss2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
 5752
 0.24
chr12_100002999_100003300 1.04 Gm23291
 predicted gene, 23291
 20297
 0.15
chr1_155990565_155990716 1.04 Gm9694
 predicted gene 9694
 17322
 0.12
chr4_57164674_57164825 1.04 Gm12530
 predicted gene 12530
 7322
 0.21
chr7_101296731_101297265 1.04 Atg16l2
 autophagy related 16-like 2 (S. cerevisiae)
 171
 0.92
chr1_186413682_186413833 1.03 Gm37491
 predicted gene, 37491
 66442
 0.12
chr14_25593992_25594143 1.03 Zmiz1
 zinc finger, MIZ-type containing 1
 13290
 0.19
chr1_52293564_52293968 1.03 Gm5975
 predicted gene 5975
 4671
 0.25
chr13_114199613_114199764 1.03 Gm37907
 predicted gene, 37907
 27423
 0.16
chr2_154565671_154565822 1.02 E2f1
 E2F transcription factor 1
 3974
 0.13
chr4_53121076_53121441 1.02 Abca1
 ATP-binding cassette, sub-family A (ABC1), member 1
 38637
 0.15
chr11_37031760_37031911 1.02 Tenm2
 teneurin transmembrane protein 2
 87669
 0.11
chr2_59700010_59700189 1.02 Tanc1
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
 6745
 0.29
chr9_103422912_103423152 1.02 Gm47328
 predicted gene, 47328
 168
 0.81
chr6_67138667_67138891 1.01 A430010J10Rik
 RIKEN cDNA A430010J10 gene
 23102
 0.14
chr15_93063824_93063975 1.01 Gm18685
 predicted gene, 18685
 25331
 0.19
chr12_116348857_116349008 1.00 Esyt2
 extended synaptotagmin-like protein 2
 1180
 0.45
chr9_45189225_45189478 1.00 BC049352
 cDNA sequence BC049352
 6415
 0.1
chr5_64403763_64403952 1.00 Gm43837
 predicted gene 43837
 20403
 0.13
chr9_70939839_70940063 1.00 Lipc
 lipase, hepatic
 5143
 0.23
chr16_35598101_35598252 0.99 Gm5963
 predicted pseudogene 5963
 24620
 0.17
chr10_50073301_50073602 0.99 Gm48131
 predicted gene, 48131
 91570
 0.07
chr14_13770655_13771021 0.99 Gm27506
 predicted gene, 27506
 7313
 0.18
chr3_78594797_78595204 0.99 Gm15442
 predicted gene 15442
 106363
 0.07
chr11_94934265_94934416 0.97 Col1a1
 collagen, type I, alpha 1
 1884
 0.23
chr7_137924852_137925061 0.97 Gm5650
 predicted gene 5650
 137050
 0.05
chr12_99445153_99445308 0.97 Foxn3
 forkhead box N3
 4844
 0.22
chr14_61960392_61960543 0.96 Gm47952
 predicted gene, 47952
 39091
 0.17
chr17_57234914_57235103 0.95 C3
 complement component 3
 6872
 0.11
chr5_74155984_74156135 0.95 A330058E17Rik
 RIKEN cDNA A330058E17 gene
 19991
 0.13
chr1_177011782_177011933 0.95 Sdccag8
 serologically defined colon cancer antigen 8
 13848
 0.14
chr17_65742516_65742902 0.95 Rab31
 RAB31, member RAS oncogene family
 29931
 0.15
chr7_96212598_96213706 0.94 Tenm4
 teneurin transmembrane protein 4
 1481
 0.42
chr8_102743048_102743212 0.94 Gm26301
 predicted gene, 26301
 10646
 0.18
chr1_40887778_40887929 0.94 Gm5973
 predicted gene 5973
 23621
 0.21
chr13_64275155_64275678 0.94 Cdc14b
 CDC14 cell division cycle 14B
 126
 0.92
chr5_21724850_21725273 0.94 Pmpcb
 peptidase (mitochondrial processing) beta
 12080
 0.12
chr16_37945571_37945750 0.94 Gpr156
 G protein-coupled receptor 156
 29164
 0.14
chr17_27294305_27294456 0.93 Mir7214
 microRNA 7214
 22715
 0.08
chr14_118132237_118133349 0.93 Tgds
 TDP-glucose 4,6-dehydratase
 38
 0.97
chr15_79830812_79830963 0.93 Cbx6
 chromobox 6
 2911
 0.13
chr19_47854442_47855082 0.93 Gsto1
 glutathione S-transferase omega 1
 208
 0.92
chr12_100998055_100998407 0.92 Gm36756
 predicted gene, 36756
 5259
 0.14
chr6_114846251_114846445 0.92 Atg7
 autophagy related 7
 9803
 0.19
chr17_28333560_28333713 0.92 Tead3
 TEA domain family member 3
 1779
 0.19
chr8_10775551_10775716 0.92 Rps16-ps3
 ribosomal protein S16, pseudogene 3
 33495
 0.11
chr10_36729750_36729997 0.91 Gm22554
 predicted gene, 22554
 46058
 0.19
chr14_3048629_3049241 0.91 Gm2897
 predicted gene 2897
 350
 0.83
chr15_52162055_52162206 0.91 Gm2387
 predicted gene 2387
 72822
 0.1
chr9_37932661_37932825 0.90 Olfr879-ps1
 olfactory receptor 879, pseudogene 1
 8672
 0.1
chr16_29046490_29046924 0.90 Gm8253
 predicted gene 8253
 95352
 0.08
chr1_56257214_56257365 0.90 Gm28900
 predicted gene 28900
 194118
 0.03
chr10_71755175_71755326 0.89 Gm6362
 predicted gene 6362
 37493
 0.13
chr8_40896668_40896819 0.89 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 1695
 0.33
chr6_29023980_29024534 0.89 Mir129-1
 microRNA 129-1
 1638
 0.36
chr3_138129159_138129496 0.88 Mttp
 microsomal triglyceride transfer protein
 2050
 0.23
chr8_116352769_116352920 0.88 1700018P08Rik
 RIKEN cDNA 1700018P08 gene
 4217
 0.34
chr18_72725028_72725395 0.88 Gm31819
 predicted gene, 31819
 144
 0.98
chr8_20588994_20589562 0.88 Gm21112
 predicted gene, 21112
 7763
 0.17
chr7_16004528_16004733 0.88 Bicra
 BRD4 interacting chromatin remodeling complex associated protein
 5135
 0.14
chr4_63166503_63166666 0.88 Kif12
 kinesin family member 12
 5146
 0.18
chr12_87002318_87002469 0.87 Zdhhc22
 zinc finger, DHHC-type containing 22
 11963
 0.13
chr9_94568059_94568210 0.87 Gm39404
 predicted gene, 39404
 24062
 0.17
chr10_115586286_115586437 0.87 Lgr5
 leucine rich repeat containing G protein coupled receptor 5
 1132
 0.5
chr5_131531798_131531960 0.87 Auts2
 autism susceptibility candidate 2
 2518
 0.28
chr1_34124137_34124288 0.87 Dst
 dystonin
 2962
 0.23
chr10_75882497_75882756 0.86 Gm47744
 predicted gene, 47744
 7195
 0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 0.8 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.2 0.7 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 1.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.8 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 1.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.2 0.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 1.5 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.4 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 1.0 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.4 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.1 0.2 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1 0.5 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.7 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.1 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.1 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.5 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.9 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.4 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.2 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.7 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.7 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.4 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1 0.2 GO:1990791 dorsal root ganglion development(GO:1990791)
0.1 1.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1 0.7 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.9 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
0.1 0.2 GO:2000618 regulation of histone H4-K16 acetylation(GO:2000618)
0.1 0.3 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.0 GO:0072525 pyridine-containing compound biosynthetic process(GO:0072525)
0.1 0.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.2 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.2 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:1904395 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0086017 Purkinje myocyte action potential(GO:0086017)
0.0 0.0 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0046075 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.9 GO:0033273 response to vitamin(GO:0033273)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.0 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0090135 actin filament branching(GO:0090135)
0.0 0.1 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0015879 carnitine transport(GO:0015879)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.0 0.1 GO:1902661 regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.1 GO:0031052 programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:1900094 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0033505 floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:1902837 amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418)
0.0 0.0 GO:1904023 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.0 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.0 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.2 GO:0015791 polyol transport(GO:0015791)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.6 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.0 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.0 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.4 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:0001964 startle response(GO:0001964)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0018904 ether metabolic process(GO:0018904)
0.0 0.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) small RNA loading onto RISC(GO:0070922)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 1.0 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0002254 kinin cascade(GO:0002254)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.0 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0009624 response to nematode(GO:0009624)
0.0 0.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.0 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.2 1.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.1 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.8 GO:0043194 axon initial segment(GO:0043194)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0098984 neuron to neuron synapse(GO:0098984)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.9 GO:0009374 biotin binding(GO:0009374)
0.2 1.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.2 0.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.9 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.3 GO:0070402 NADPH binding(GO:0070402)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.0 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 1.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0031014 troponin T binding(GO:0031014)
0.1 0.2 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.8 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0016917 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0038064 collagen receptor activity(GO:0038064)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0032142 single guanine insertion binding(GO:0032142)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0016934 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 3.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID ATM PATHWAY ATM pathway
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones