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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Glis3

Z-value: 0.69

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Transcription factors associated with Glis3

Gene Symbol	Gene ID	Gene Info
Glis3 Ensembl NCBI MGI UniProt	ENSMUSG00000052942.7	GLIS family zinc finger 3
Glis3 Ensembl NCBI MGI UniProt	ENSMUSG00000091294.1	GLIS family zinc finger 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_28328619_28328770	Glis3	2688	0.402656	0.57	6.3e-06	Click!
chr19_28679781_28680338	Glis3	18	0.971293	0.46	4.7e-04	Click!
chr19_28641105_28641256	Glis3	25505	0.170254	0.27	4.3e-02	Click!
chr19_28380638_28380789	Glis3	54707	0.160298	0.26	5.5e-02	Click!
chr19_28436583_28436752	Glis3	103753	0.071479	0.24	7.2e-02	Click!

Activity of the Glis3 motif across conditions

Conditions sorted by the z-value of the Glis3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_67471274_67471636	1.99	Gm33926	predicted gene, 33926	27522	0.17
chr5_138997857_138998317	1.69	Pdgfa	platelet derived growth factor, alpha	717	0.64
chr5_120005810_120006020	1.66	Gm38554	predicted gene, 38554	46672	0.13
chr5_137348677_137348944	1.63	Ephb4	Eph receptor B4	1299	0.25
chr12_3834339_3834973	1.62	Dnmt3a	DNA methyltransferase 3A	14979	0.17
chr14_54971406_54971557	1.48	Gm29015	predicted gene 29015	1548	0.13
chr3_69588417_69588708	1.47	B3galnt1	UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1	10398	0.17
chr5_119836588_119836964	1.35	Tbx5	T-box 5	621	0.7
chr15_93825328_93825719	1.23	Gm49445	predicted gene, 49445	485	0.86
chr4_147969190_147969341	1.15	Nppb	natriuretic peptide type B	16523	0.09
chr10_45181043_45181210	1.14	Popdc3	popeye domain containing 3	3028	0.27
chr11_72041836_72042510	1.14	Pimreg	PICALM interacting mitotic regulator	141	0.94
chr1_171189506_171189734	1.13	Pcp4l1	Purkinje cell protein 4-like 1	6648	0.09
chr5_122100700_122101295	1.12	Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	14	0.97
chr14_25365371_25365579	1.12	Gm26660	predicted gene, 26660	13160	0.21
chr16_44687184_44688343	1.10	Nepro	nucleolus and neural progenitor protein	36538	0.14
chr2_30604975_30605527	1.07	Cstad	CSA-conditional, T cell activation-dependent protein	34	0.97
chr2_32317120_32318698	1.05	Gm23363	predicted gene, 23363	356	0.45
chr3_89391710_89392572	1.04	Zbtb7b	zinc finger and BTB domain containing 7B	72	0.62
chr18_75378512_75379142	1.01	Smad7	SMAD family member 7	3913	0.25
chr2_120094110_120094375	1.00	Sptbn5	spectrin beta, non-erythrocytic 5	8564	0.15
chr17_29451348_29451678	1.00	Gm36199	predicted gene, 36199	2161	0.2
chr14_62259091_62259242	0.99	Rnaseh2b	ribonuclease H2, subunit B	33423	0.15
chr13_55510408_55510601	0.98	Pdlim7	PDZ and LIM domain 7	1484	0.19
chr7_105580903_105581664	0.97	Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	5	0.95
chr11_61484326_61485106	0.91	Mfap4	microfibrillar-associated protein 4	715	0.53
chr2_33966954_33967150	0.90	Gm13404	predicted gene 13404	11194	0.21
chr6_85254101_85254349	0.89	Sfxn5	sideroflexin 5	10708	0.16
chr11_70468019_70468408	0.88	Zmynd15	zinc finger, MYND-type containing 15	7648	0.07
chr5_125264626_125264993	0.86	Gm32585	predicted gene, 32585	8006	0.18
chr8_102786608_102786857	0.82	Cdh11	cadherin 11	1090	0.52
chr9_77352516_77352683	0.82	Mlip	muscular LMNA-interacting protein	370	0.84
chr10_99534471_99534622	0.82	Gm48085	predicted gene, 48085	3523	0.24
chr6_88937928_88938520	0.82	4933427D06Rik	RIKEN cDNA 4933427D06 gene	12459	0.13
chr3_108085301_108086522	0.82	Gm12500	predicted gene 12500	65	0.8
chr14_27114666_27114961	0.80	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	86	0.98
chr14_21988166_21988548	0.78	Zfp503	zinc finger protein 503	1244	0.37
chr11_80809988_80810207	0.77	Tmem98	transmembrane protein 98	78	0.97
chr17_4866022_4866173	0.76	4930579D07Rik	RIKEN cDNA 4930579D07 gene	11615	0.2
chr10_111594710_111594919	0.76	4933440J02Rik	RIKEN cDNA 4933440J02 gene	541	0.73
chr7_79149006_79149317	0.76	Mfge8	milk fat globule-EGF factor 8 protein	101	0.97
chr8_14911749_14912202	0.74	Arhgef10	Rho guanine nucleotide exchange factor (GEF) 10	237	0.92
chr14_52014304_52014473	0.74	Zfp219	zinc finger protein 219	194	0.83
chr7_142657124_142657560	0.74	Igf2	insulin-like growth factor 2	124	0.92
chr7_126582804_126583424	0.74	Cln3	ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)	0	0.93
chr2_35684118_35684369	0.73	Dab2ip	disabled 2 interacting protein	7751	0.24
chr13_30782030_30782219	0.73	Gm29675	predicted gene, 29675	13102	0.19
chr7_29453052_29453769	0.73	Sipa1l3	signal-induced proliferation-associated 1 like 3	52042	0.1
chr16_44632721_44633371	0.72	Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	74149	0.08
chr9_14596490_14596733	0.72	Amotl1	angiomotin-like 1	17975	0.12
chr8_11357901_11358379	0.72	Col4a1	collagen, type IV, alpha 1	45314	0.1
chr3_79690130_79690466	0.72	Gm26984	predicted gene, 26984	13422	0.15
chr16_43503682_43504014	0.71	Zbtb20	zinc finger and BTB domain containing 20	151	0.97
chr1_39288126_39288277	0.70	Gm20428	predicted gene 20428	11636	0.17
chr17_67170823_67170977	0.70	Ptprm	protein tyrosine phosphatase, receptor type, M	122915	0.05
chr13_37629070_37629705	0.70	Gm40915	predicted gene, 40915	1784	0.24
chr2_36104921_36105072	0.69	Lhx6	LIM homeobox protein 6	105	0.95
chr2_28446566_28447382	0.68	Ppp1r26	protein phosphatase 1, regulatory subunit 26	108	0.95
chr13_60737684_60738259	0.68	Dapk1	death associated protein kinase 1	16025	0.15
chr6_53218861_53219048	0.67	Gm4872	predicted gene 4872	2210	0.36
chr3_95687508_95688286	0.67	Adamtsl4	ADAMTS-like 4	20	0.96
chr11_71747926_71748095	0.67	Wscd1	WSC domain containing 1	1910	0.3
chr19_47885000_47885151	0.67	Gsto2	glutathione S-transferase omega 2	14813	0.13
chr14_27622251_27622923	0.66	Erc2	ELKS/RAB6-interacting/CAST family member 2	77	0.98
chr12_45022163_45022314	0.66	Stxbp6	syntaxin binding protein 6 (amisyn)	9274	0.23
chr10_81559146_81561402	0.65	Tle5	TLE family member 5, transcriptional modulator	770	0.38
chr4_66894714_66894865	0.65	Tlr4	toll-like receptor 4	66587	0.14
chr14_120637683_120637943	0.65	Gm49008	predicted gene, 49008	4851	0.28
chr7_139467729_139467880	0.65	Inpp5a	inositol polyphosphate-5-phosphatase A	13750	0.24
chr12_16553856_16554148	0.64	Lpin1	lipin 1	8036	0.26
chr5_122102023_122102402	0.64	Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	415	0.79
chr12_108371321_108371691	0.64	Eml1	echinoderm microtubule associated protein like 1	549	0.75
chr17_44300705_44301078	0.64	Clic5	chloride intracellular channel 5	63785	0.12
chr18_55815948_55816458	0.64	Gm8614	predicted gene 8614	22746	0.19
chr5_122950982_122952145	0.63	Kdm2b	lysine (K)-specific demethylase 2B	427	0.77
chr15_82961007_82961398	0.63	Mir3080	microRNA 3080	1906	0.23
chr17_71039919_71040277	0.62	Myom1	myomesin 1	20507	0.12
chr10_86371635_86371796	0.62	Timp3	tissue inhibitor of metalloproteinase 3	68861	0.08
chr11_94883072_94883246	0.61	A430060F13Rik	RIKEN cDNA A430060F13 gene	21400	0.11
chr1_74284190_74285456	0.60	Aamp	angio-associated migratory protein	85	0.51
chr13_48260396_48261208	0.60	Id4	inhibitor of DNA binding 4	426	0.7
chr3_89315223_89316179	0.60	Gm15998	predicted gene 15998	262	0.77
chr17_26424377_26424632	0.60	Neurl1b	neuralized E3 ubiquitin protein ligase 1B	9539	0.14
chr14_120705317_120705468	0.60	Rpl19-ps5	ribosomal protein L19, pseudogene 5	7686	0.21
chr1_74025160_74025359	0.60	Tns1	tensin 1	8837	0.23
chr15_97055229_97055380	0.59	Slc38a4	solute carrier family 38, member 4	652	0.81
chrX_160418379_160418554	0.58	Adgrg2	adhesion G protein-coupled receptor G2	8826	0.22
chr3_87971441_87971954	0.58	Nes	nestin	568	0.56
chr13_63573352_63573844	0.58	Ptch1	patched 1	0	0.96
chr14_54994259_54994475	0.58	Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	176	0.85
chr2_114052677_114053403	0.57	Actc1	actin, alpha, cardiac muscle 1	153	0.93
chr1_90897082_90897304	0.57	Mlph	melanophilin	17892	0.14
chr8_115250365_115250516	0.57	Gm22556	predicted gene, 22556	197527	0.03
chrX_150814229_150814429	0.57	Maged2	melanoma antigen, family D, 2	16	0.97
chr18_76469688_76469918	0.56	Gm50360	predicted gene, 50360	147979	0.04
chr10_42614130_42614512	0.56	Ostm1	osteopetrosis associated transmembrane protein 1	30483	0.16
chr13_41345306_41345621	0.56	Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	13784	0.14
chr6_126646041_126646221	0.56	Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	253	0.93
chr18_36017856_36019112	0.56	Nrg2	neuregulin 2	13457	0.16
chr16_85803746_85803905	0.56	Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	712	0.73
chr3_96181091_96181472	0.55	Sv2a	synaptic vesicle glycoprotein 2 a	130	0.86
chr19_36348119_36348437	0.54	Gm47735	predicted gene, 47735	20	0.5
chr9_107593161_107593336	0.54	Ifrd2	interferon-related developmental regulator 2	621	0.32
chr17_26865252_26865474	0.54	Gm20468	predicted gene 20468	3942	0.12
chr11_61485173_61485597	0.54	Mfap4	microfibrillar-associated protein 4	46	0.96
chr5_105346543_105346806	0.54	Gbp11	guanylate binding protein 11	202	0.94
chr4_100101880_100102395	0.53	Ror1	receptor tyrosine kinase-like orphan receptor 1	6346	0.22
chr14_31205580_31207467	0.53	Nisch	nischarin	177	0.89
chr3_79907276_79907427	0.53	Gm36569	predicted gene, 36569	20545	0.17
chr2_157058410_157059040	0.53	Soga1	suppressor of glucose, autophagy associated 1	18486	0.12
chr11_80316377_80316533	0.53	Rhbdl3	rhomboid like 3	3235	0.24
chr16_35215095_35215432	0.52	Gm25179	predicted gene, 25179	19660	0.19
chr1_153172459_153172671	0.52	Lamc2	laminin, gamma 2	13482	0.2
chr11_101232085_101232549	0.52	Ezh1	enhancer of zeste 1 polycomb repressive complex 2 subunit	5854	0.08
chr1_193734040_193734306	0.51	Gm21362	predicted gene, 21362	132836	0.05
chr5_114671329_114671480	0.51	Trpv4	transient receptor potential cation channel, subfamily V, member 4	12983	0.12
chr4_152273539_152274471	0.51	Gpr153	G protein-coupled receptor 153	227	0.89
chr10_126927498_126927649	0.51	Atp23	ATP23 metallopeptidase and ATP synthase assembly factor homolog	26218	0.09
chr3_73056881_73057482	0.51	Slitrk3	SLIT and NTRK-like family, member 3	238	0.92
chr6_97487685_97488107	0.51	Frmd4b	FERM domain containing 4B	91	0.97
chr11_97659525_97659953	0.51	Gm24158	predicted gene, 24158	588	0.37
chr5_65106807_65107827	0.50	Klhl5	kelch-like 5	222	0.92
chr18_82912875_82914544	0.50	Zfp516	zinc finger protein 516	923	0.51
chr1_134333064_134333269	0.50	Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	238	0.89
chr10_63457395_63457598	0.49	Ctnna3	catenin (cadherin associated protein), alpha 3	14	0.98
chr19_55757537_55757688	0.49	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	14767	0.27
chr9_102689518_102690683	0.49	4930533D04Rik	RIKEN cDNA 4930533D04 gene	2785	0.18
chr6_128028583_128028766	0.49	Tspan9	tetraspanin 9	5918	0.2
chr13_53237536_53237687	0.49	Ror2	receptor tyrosine kinase-like orphan receptor 2	38047	0.19
chr10_83648138_83649089	0.49	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	10	0.98
chr9_50722434_50722597	0.48	Dixdc1	DIX domain containing 1	5423	0.13
chr1_156779038_156779543	0.48	Gm15428	predicted pseudogene 15428	14222	0.15
chr19_4711655_4711852	0.48	Sptbn2	spectrin beta, non-erythrocytic 2	586	0.61
chr8_47413184_47413712	0.48	Stox2	storkhead box 2	389	0.87
chr8_71498904_71499355	0.48	Gtpbp3	GTP binding protein 3	9670	0.07
chr8_88567927_88568131	0.47	Gm45496	predicted gene 45496	7996	0.2
chr5_138912148_138912327	0.47	Pdgfa	platelet derived growth factor, alpha	82044	0.07
chr11_59009654_59009805	0.47	Gm10435	predicted gene 10435	6819	0.09
chr8_11331273_11331424	0.47	Col4a1	collagen, type IV, alpha 1	18522	0.15
chr11_20858852_20859410	0.47	Gm22807	predicted gene, 22807	11250	0.15
chr6_83794439_83795940	0.47	Nagk	N-acetylglucosamine kinase	19	0.94
chr12_112147478_112147709	0.47	Kif26a	kinesin family member 26A	1385	0.33
chr2_152048577_152049360	0.47	AA387200	expressed sequence AA387200	27840	0.11
chr15_74487345_74487780	0.46	Adgrb1	adhesion G protein-coupled receptor B1	28633	0.16
chr5_77358327_77358734	0.46	Polr2b	polymerase (RNA) II (DNA directed) polypeptide B	18162	0.13
chr5_119794079_119794230	0.46	1700021F13Rik	RIKEN cDNA 1700021F13 gene	13513	0.17
chr16_32854480_32854631	0.46	Rubcn	RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein	13783	0.13
chr8_57321535_57322223	0.46	Hand2os1	Hand2, opposite strand 1	651	0.47
chr4_117124515_117125246	0.46	Btbd19	BTB (POZ) domain containing 19	286	0.73
chr13_56703202_56704180	0.46	Smad5	SMAD family member 5	23	0.98
chr18_42978690_42978841	0.45	Ppp2r2b	protein phosphatase 2, regulatory subunit B, beta	40533	0.15
chr11_98935983_98936905	0.45	Rara	retinoic acid receptor, alpha	1254	0.3
chr9_56505269_56505564	0.45	Gm47175	predicted gene, 47175	1245	0.42
chr10_58233022_58233496	0.45	Duxf3	double homeobox family member 3	584	0.62
chr1_58030580_58030815	0.45	Aox1	aldehyde oxidase 1	733	0.64
chr18_35918777_35919433	0.45	Gm50405	predicted gene, 50405	4190	0.13
chr3_94582467_94582919	0.45	Snx27	sorting nexin family member 27	14	0.95
chr1_156780969_156781575	0.45	Gm15428	predicted pseudogene 15428	12240	0.15
chr10_38986094_38986316	0.45	Lama4	laminin, alpha 4	20533	0.22
chr11_7055456_7055607	0.45	Adcy1	adenylate cyclase 1	7958	0.26
chr10_62016778_62017263	0.44	Gm47919	predicted gene, 47919	6384	0.19
chr9_118694402_118694558	0.44	Itga9	integrin alpha 9	8645	0.24
chr13_18043214_18043365	0.44	Gm6575	predicted gene 6575	4728	0.14
chr3_34642143_34642294	0.44	Gm42692	predicted gene 42692	1046	0.36
chr2_166196150_166196314	0.44	Gm11466	predicted gene 11466	5370	0.17
chr2_65567574_65567908	0.44	Scn3a	sodium channel, voltage-gated, type III, alpha	114	0.97
chr7_67910990_67911267	0.44	Gm44666	predicted gene 44666	24543	0.16
chr17_4173988_4174168	0.44	4930548J01Rik	RIKEN cDNA 4930548J01 gene	51965	0.17
chr11_118360927_118361104	0.44	Timp2	tissue inhibitor of metalloproteinase 2	5275	0.16
chr5_124964039_124964493	0.44	Rflna	refilin A	38955	0.13
chr18_80712591_80713347	0.44	Nfatc1	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	89	0.97
chr1_179667564_179668717	0.44	Sccpdh	saccharopine dehydrogenase (putative)	70	0.98
chr19_16132209_16133500	0.43	Gnaq	guanine nucleotide binding protein, alpha q polypeptide	23	0.98
chr9_8003315_8004975	0.43	Yap1	yes-associated protein 1	245	0.79
chr5_132334819_132335092	0.43	Gm42989	predicted gene 42989	37726	0.16
chr10_80936253_80937073	0.43	Gadd45b	growth arrest and DNA-damage-inducible 45 beta	5851	0.1
chr13_80962745_80963559	0.43	9330111N05Rik	RIKEN cDNA 9330111N05 gene	264	0.71
chr15_83487585_83487761	0.43	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	23067	0.11
chr5_65107840_65108141	0.43	Klhl5	kelch-like 5	451	0.8
chr3_89280469_89281651	0.43	Efna1	ephrin A1	82	0.91
chr8_82967937_82968088	0.43	Gm18212	predicted gene, 18212	15500	0.24
chr1_133255964_133256140	0.43	Gm19461	predicted gene, 19461	300	0.64
chr16_33580751_33581254	0.43	Slc12a8	solute carrier family 12 (potassium/chloride transporters), member 8	15560	0.25
chr2_59824280_59824521	0.43	Tanc1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	17340	0.21
chr15_80000729_80000880	0.42	Mir7213	microRNA 7213	1778	0.23
chr7_74012764_74012935	0.42	St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	825	0.64
chr15_99771905_99772913	0.42	Cers5	ceramide synthase 5	53	0.94
chr10_97565444_97565849	0.42	Lum	lumican	518	0.78
chr4_120131881_120132032	0.42	Edn2	endothelin 2	29250	0.18
chr10_56376223_56376507	0.42	Gja1	gap junction protein, alpha 1	965	0.58
chr10_79926423_79927890	0.42	Arid3a	AT rich interactive domain 3A (BRIGHT-like)	17	0.92
chr15_101294156_101294470	0.42	Smim41	small integral membrane protein 41	1081	0.33
chr13_30659801_30660671	0.42	Dusp22	dual specificity phosphatase 22	135	0.97
chr18_60656319_60656539	0.42	Synpo	synaptopodin	3713	0.22
chr4_84199256_84199407	0.42	Gm12414	predicted gene 12414	69042	0.11
chr6_5802451_5802946	0.42	Dync1i1	dynein cytoplasmic 1 intermediate chain 1	45279	0.2
chr16_26185747_26186199	0.42	P3h2	prolyl 3-hydroxylase 2	80189	0.11
chr12_29532917_29533068	0.41	Myt1l	myelin transcription factor 1-like	393	0.85
chr8_40975906_40976229	0.41	Mtus1	mitochondrial tumor suppressor 1	24138	0.14
chr8_70493079_70493663	0.41	Crlf1	cytokine receptor-like factor 1	10	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:1900238	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.4	1.1	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.3	1.6	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.2	0.7	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2	0.6	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2	0.9	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.2	0.9	GO:0003163	sinoatrial node development(GO:0003163)
0.2	0.7	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.2	0.5	GO:0046684	response to pyrethroid(GO:0046684)
0.2	0.5	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.6	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.1	0.4	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.1	1.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.7	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.5	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.4	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.4	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.1	0.4	GO:0045297	mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.1	0.4	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.5	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	0.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.1	0.5	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.3	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1	0.3	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.1	0.3	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	0.4	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.1	0.7	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.5	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.1	0.3	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	0.5	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.6	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1	0.8	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.3	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.3	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.7	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.1	0.4	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.1	0.2	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.1	0.5	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.3	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.1	0.2	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.2	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.4	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.3	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1	0.2	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1	0.7	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.6	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.1	0.2	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1	0.4	GO:0070314	G1 to G0 transition(GO:0070314)
0.1	0.4	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.1	0.3	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.1	0.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.3	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.1	0.3	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1	0.1	GO:0021586	pons maturation(GO:0021586)
0.1	0.2	GO:0022009	central nervous system vasculogenesis(GO:0022009)
0.1	0.3	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.8	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.2	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	0.3	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1	0.3	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.2	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.2	GO:0035799	ureter maturation(GO:0035799)
0.1	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.4	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.1	0.2	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1	0.3	GO:0009115	xanthine catabolic process(GO:0009115)
0.1	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.2	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.1	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	0.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.2	GO:0015819	lysine transport(GO:0015819)
0.1	0.1	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.1	GO:0060618	nipple development(GO:0060618)
0.1	0.1	GO:0060486	Clara cell differentiation(GO:0060486)
0.1	0.2	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.1	0.2	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.2	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.2	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	0.2	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.3	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.6	GO:0043129	surfactant homeostasis(GO:0043129)
0.0	0.1	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.2	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.3	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.0	GO:0035993	deltoid tuberosity development(GO:0035993)
0.0	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.6	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.3	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.2	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.1	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0032264	IMP salvage(GO:0032264)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.4	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0061642	chemoattraction of axon(GO:0061642)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:1901844	cell communication by electrical coupling involved in cardiac conduction(GO:0086064) negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.2	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:1903365	regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.0	0.4	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.6	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.2	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.2	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.2	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0	0.6	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.0	0.2	GO:2000618	regulation of histone H4-K16 acetylation(GO:2000618)
0.0	0.1	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.2	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.3	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.7	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.3	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.3	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.2	GO:0061196	fungiform papilla development(GO:0061196)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	1.4	GO:0008542	visual learning(GO:0008542)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.3	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.2	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.1	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.2	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.1	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.4	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.3	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.2	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.3	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.4	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0	0.1	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.2	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.5	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:1903998	regulation of eating behavior(GO:1903998)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.1	GO:0043328	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0	0.1	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.2	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.1	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0072498	embryonic skeletal joint development(GO:0072498)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0001794	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.0	0.0	GO:0098815	modulation of excitatory postsynaptic potential(GO:0098815)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.2	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.2	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.0	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.6	GO:0001990	regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.3	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.0	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.4	GO:0009409	response to cold(GO:0009409)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.0	GO:0021557	oculomotor nerve development(GO:0021557)
0.0	0.0	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.0	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	0.3	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.3	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0060074	synapse maturation(GO:0060074)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.0	0.1	GO:0046909	intermembrane transport(GO:0046909)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.3	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0061377	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.2	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.2	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.2	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.3	GO:0021954	central nervous system neuron development(GO:0021954)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.1	GO:0045762	positive regulation of adenylate cyclase activity(GO:0045762)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.0	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.1	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:1904377	positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.0	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:1990812	growth cone filopodium(GO:1990812)
0.2	1.0	GO:0071953	elastic fiber(GO:0071953)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.1	0.4	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	1.1	GO:0005916	fascia adherens(GO:0005916)
0.1	0.5	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.7	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.5	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.4	GO:0008091	spectrin(GO:0008091)
0.1	0.6	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.2	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.1	0.6	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0044294	dendritic growth cone(GO:0044294)
0.1	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	1.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.3	GO:0097542	ciliary tip(GO:0097542)
0.0	0.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	1.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.1	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.2	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.4	GO:0005605	basal lamina(GO:0005605)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	1.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.0	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.4	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.9	GO:0042641	actomyosin(GO:0042641)
0.0	1.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.3	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	1.2	GO:0005901	caveola(GO:0005901)
0.0	0.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.9	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.0	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.5	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.3	GO:0014704	intercalated disc(GO:0014704)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.0	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.3	GO:0000791	euchromatin(GO:0000791)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.9	GO:0001726	ruffle(GO:0001726)
0.0	2.6	GO:0031012	extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	0.5	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.2	1.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.6	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.1	0.4	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.9	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.3	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.5	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.8	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.3	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.3	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.7	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	1.7	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0070905	serine binding(GO:0070905)
0.1	0.5	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.3	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	1.2	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.4	GO:0070411	I-SMAD binding(GO:0070411)
0.1	1.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0071253	connexin binding(GO:0071253)
0.1	0.7	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.1	0.3	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	0.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.3	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.2	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.2	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.9	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.1	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.2	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.4	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.7	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.2	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.4	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.3	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	1.1	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0031005	filamin binding(GO:0031005)
0.0	0.0	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.3	GO:0032183	SUMO binding(GO:0032183)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	1.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	1.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0019767	IgE receptor activity(GO:0019767)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.0	GO:0018591	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.0	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	1.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.4	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.5	GO:0004394	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0	0.2	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.0	GO:0004673	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0	0.2	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.3	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.3	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0	0.6	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	2.5	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.3	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	2.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling

Results for Glis3

Z-value: 0.69

Motif logo

Transcription factors associated with Glis3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Glis3 motif across conditions

Conditions sorted by the z-value of the Glis3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: