Project

ENCODE: ATAC-seq of different tissues during embryonic development

Navigation

Downloads

Results for Hic1

Z-value: 2.24

Motif logo

Transcription factors associated with Hic1

Gene Symbol	Gene ID	Gene Info
Hic1 Ensembl NCBI MGI UniProt	ENSMUSG00000043099.4	hypermethylated in cancer 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_75166966_75167344	Hic1	991	0.334290	0.32	1.6e-02	Click!
chr11_75168044_75169075	Hic1	413	0.684110	0.32	1.6e-02	Click!
chr11_75169730_75170036	Hic1	364	0.715807	0.23	8.8e-02	Click!
chr11_75169094_75169322	Hic1	311	0.771413	0.19	1.7e-01	Click!
chr11_75167503_75167654	Hic1	568	0.560977	0.14	3.2e-01	Click!

Activity of the Hic1 motif across conditions

Conditions sorted by the z-value of the Hic1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_77564959_77566098	11.00	Rnf165	ring finger protein 165	367	0.89
chr9_106886021_106887464	10.10	Rbm15b	RNA binding motif protein 15B	686	0.53
chr10_32889642_32890523	9.86	Nkain2	Na+/K+ transporting ATPase interacting 2	234	0.95
chr8_23411129_23412450	9.33	Sfrp1	secreted frizzled-related protein 1	287	0.94
chr7_84409236_84410328	9.07	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	101	0.96
chr3_145987459_145988897	8.63	Syde2	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	41	0.98
chr8_57321535_57322223	8.40	Hand2os1	Hand2, opposite strand 1	651	0.47
chr8_125569269_125570645	8.10	Sipa1l2	signal-induced proliferation-associated 1 like 2	149	0.97
chr10_9674551_9675589	7.96	Samd5	sterile alpha motif domain containing 5	138	0.95
chr17_13759899_13761731	7.90	Afdn	afadin, adherens junction formation factor	141	0.73
chr8_127063794_127064607	7.85	Pard3	par-3 family cell polarity regulator	45	0.97
chr12_112678481_112679637	7.84	Zbtb42	zinc finger and BTB domain containing 42	181	0.89
chr17_66448520_66450314	7.61	Mtcl1	microtubule crosslinking factor 1	333	0.57
chr13_72628074_72629485	7.53	Irx2	Iroquois homeobox 2	41	0.73
chr6_99692354_99692948	7.19	Gpr27	G protein-coupled receptor 27	28	0.97
chr18_36017856_36019112	7.18	Nrg2	neuregulin 2	13457	0.16
chr11_89302295_89302892	7.14	Gm2018	predicted gene 2018	130	0.68
chr2_157078595_157079557	7.07	Soga1	suppressor of glucose, autophagy associated 1	178	0.93
chr17_85687855_85689066	7.05	Six2	sine oculis-related homeobox 2	186	0.94
chr8_15027100_15028701	6.92	Gm37844	predicted gene, 37844	522	0.44
chr2_77816275_77817277	6.90	Zfp385b	zinc finger protein 385B	40	0.98
chr16_18620677_18621820	6.82	Gp1bb	glycoprotein Ib, beta polypeptide	392	0.75
chr6_119543741_119544508	6.79	Wnt5b	wingless-type MMTV integration site family, member 5B	194	0.95
chr12_103242082_103243024	6.72	Prima1	proline rich membrane anchor 1	403	0.85
chr7_64501527_64502724	6.64	Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	13	0.98
chr4_114405732_114406986	6.06	Trabd2b	TraB domain containing 2B	365	0.93
chr13_83730468_83731674	5.94	Gm26803	predicted gene, 26803	1489	0.25
chr10_79681206_79682337	5.90	Cdc34	cell division cycle 34	424	0.63
chr5_65106807_65107827	5.87	Klhl5	kelch-like 5	222	0.92
chr15_85669900_85671551	5.76	Lncppara	long noncoding RNA near Ppara	17109	0.13
chr1_21960934_21962001	5.58	Kcnq5	potassium voltage-gated channel, subfamily Q, member 5	114	0.98
chr1_63445869_63446575	5.45	Adam23	a disintegrin and metallopeptidase domain 23	11	0.98
chr5_38158989_38159808	5.42	Nsg1	neuron specific gene family member 1	7	0.97
chr17_50292589_50293643	5.41	Dazl	deleted in azoospermia-like	224	0.93
chr18_82164402_82165095	5.30	Gm50294	predicted gene, 50294	93762	0.06
chr12_108422834_108423697	5.30	Eml1	echinoderm microtubule associated protein like 1	187	0.95
chr7_19473848_19474484	5.30	Gm45167	predicted gene 45167	5938	0.08
chr4_124656772_124657969	5.27	Gm2164	predicted gene 2164	201	0.77
chr14_120830371_120830865	5.25	Gm9391	predicted gene 9391	3460	0.2
chr10_31609196_31610069	5.22	Rnf217	ring finger protein 217	448	0.82
chr15_86033262_86033934	5.17	Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1	605	0.74
chr12_80518528_80519832	5.17	Galnt16	polypeptide N-acetylgalactosaminyltransferase 16	190	0.58
chr2_52857330_52857884	5.15	Fmnl2	formin-like 2	253	0.95
chr11_66526100_66526559	5.14	Shisa6	shisa family member 6	365	0.91
chr6_87980723_87981994	5.11	H1f10	H1.10 linker histone	279	0.39
chr6_137648575_137649727	5.08	Eps8	epidermal growth factor receptor pathway substrate 8	78	0.98
chr14_115040506_115042372	5.08	Mir17hg	Mir17 host gene (non-protein coding)	1440	0.19
chr18_82161587_82162228	5.05	Gm50294	predicted gene, 50294	96603	0.06
chr16_94526000_94527258	5.04	Vps26c	VPS26 endosomal protein sorting factor C	188	0.94
chr8_105170389_105171616	5.00	Cbfb	core binding factor beta	57	0.94
chr15_25364173_25365245	4.96	4930445E18Rik	RIKEN cDNA 4930445E18 gene	32050	0.14
chr17_71782235_71783145	4.96	Clip4	CAP-GLY domain containing linker protein family, member 4	73	0.97
chr6_99666291_99667273	4.94	Eif4e3	eukaryotic translation initiation factor 4E member 3	11	0.49
chr7_3414948_3415832	4.88	Gm23450	predicted gene, 23450	324	0.76
chr13_68998724_69000129	4.80	Adcy2	adenylate cyclase 2	115	0.87
chr10_122985267_122986641	4.72	D630033A02Rik	RIKEN cDNA D630033A02 gene	123	0.65
chr10_125388906_125389759	4.69	Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7	36	0.95
chr4_108779892_108781170	4.69	Zfyve9	zinc finger, FYVE domain containing 9	28	0.97
chr2_61811420_61812187	4.57	Tbr1	T-box brain gene 1	5530	0.2
chr4_100776792_100777969	4.57	Cachd1	cache domain containing 1	705	0.79
chr10_83337112_83337951	4.53	Slc41a2	solute carrier family 41, member 2	91	0.96
chr3_132949340_132950694	4.51	Npnt	nephronectin	26	0.97
chr4_116877603_116878028	4.50	Zswim5	zinc finger SWIM-type containing 5	439	0.67
chr5_69340326_69341842	4.45	Gm24368	predicted gene, 24368	301	0.69
chr6_101377108_101377847	4.45	Pdzrn3	PDZ domain containing RING finger 3	135	0.96
chr13_73846884_73847811	4.43	Nkd2	naked cuticle 2	264	0.89
chr2_66124084_66125291	4.43	Galnt3	polypeptide N-acetylgalactosaminyltransferase 3	307	0.72
chr12_117153628_117154553	4.32	Gm10421	predicted gene 10421	2439	0.42
chr4_48584803_48585524	4.29	Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1	11	0.98
chr4_45184399_45185347	4.27	Frmpd1	FERM and PDZ domain containing 1	2	0.98
chr7_81933728_81934913	4.26	Hdgfl3	HDGF like 3	139	0.94
chr8_12756494_12757951	4.25	Atp11a	ATPase, class VI, type 11A	153	0.95
chr19_36553934_36555231	4.25	Hectd2	HECT domain E3 ubiquitin protein ligase 2	57	0.98
chr19_36057285_36057826	4.24	Htr7	5-hydroxytryptamine (serotonin) receptor 7	48	0.98
chr1_166308870_166309730	4.19	5330438I03Rik	RIKEN cDNA 5330438I03 gene	285	0.91
chr15_30172351_30173308	4.14	Ctnnd2	catenin (cadherin associated protein), delta 2	138	0.98
chr7_65155656_65156991	4.12	Fam189a1	family with sequence similarity 189, member A1	93	0.97
chr4_101068780_101069771	4.12	Raver2	ribonucleoprotein, PTB-binding 2	204	0.93
chr7_19094759_19096427	4.09	Six5	sine oculis-related homeobox 5	999	0.28
chr13_15462780_15463366	4.08	Gli3	GLI-Kruppel family member GLI3	162	0.76
chr16_37776737_37777678	4.08	Fstl1	follistatin-like 1	55	0.98
chr6_61179832_61181181	4.07	Ccser1	coiled-coil serine rich 1	31	0.76
chr1_93754379_93755416	4.07	Atg4b	autophagy related 4B, cysteine peptidase	8	0.5
chr2_54436378_54437149	4.05	Galnt13	polypeptide N-acetylgalactosaminyltransferase 13	272	0.95
chr9_96888753_96890030	4.03	Pxylp1	2-phosphoxylose phosphatase 1	22	0.97
chr8_121652380_121653356	4.03	Zcchc14	zinc finger, CCHC domain containing 14	33	0.95
chr10_83648138_83649089	4.02	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	10	0.98
chr13_31625869_31626532	4.02	Gm27516	predicted gene, 27516	343	0.37
chr12_86882228_86883612	4.00	Irf2bpl	interferon regulatory factor 2 binding protein-like	1878	0.33
chr1_38626793_38628168	4.00	Aff3	AF4/FMR2 family, member 3	279	0.94
chr1_165281854_165282892	3.95	Gpr161	G protein-coupled receptor 161	13416	0.16
chr4_81442019_81442668	3.95	Mpdz	multiple PDZ domain protein	301	0.93
chr17_27203606_27204996	3.93	Lemd2	LEM domain containing 2	168	0.9
chr2_35621578_35622379	3.93	Dab2ip	disabled 2 interacting protein	3	0.98
chr8_121084168_121084657	3.92	Foxf1	forkhead box F1	26	0.79
chr16_28928734_28930302	3.92	Mb21d2	Mab-21 domain containing 2	155	0.97
chr1_25829654_25830461	3.90	Adgrb3	adhesion G protein-coupled receptor B3	350	0.61
chr10_18318282_18319172	3.86	Nhsl1	NHS-like 1	258	0.91
chr5_24601908_24602410	3.83	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	147	0.91
chr8_32008598_32009895	3.83	Nrg1	neuregulin 1	64	0.99
chr1_92831123_92832495	3.83	Gpc1	glypican 1	160	0.92
chr3_103576080_103576684	3.82	Syt6	synaptotagmin VI	240	0.92
chr19_16132209_16133500	3.79	Gnaq	guanine nucleotide binding protein, alpha q polypeptide	23	0.98
chr8_46210360_46210863	3.77	Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4	419	0.73
chr7_100930787_100931664	3.75	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	882	0.51
chr3_86920207_86921011	3.71	Dclk2	doublecortin-like kinase 2	230	0.91
chr6_114968557_114970098	3.71	Vgll4	vestigial like family member 4	147	0.97
chr16_38742372_38743125	3.68	B4galt4	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4	427	0.78
chr7_3331892_3332177	3.65	Cacng7	calcium channel, voltage-dependent, gamma subunit 7	921	0.35
chr5_24474278_24475196	3.65	Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	523	0.59
chr7_57508956_57510254	3.62	Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	234	0.95
chr2_38339333_38339958	3.59	Lhx2	LIM homeobox protein 2	157	0.94
chr10_116472994_116474473	3.58	Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4	145	0.69
chr5_115429294_115430226	3.57	Msi1	musashi RNA-binding protein 1	61	0.76
chr9_8003315_8004975	3.57	Yap1	yes-associated protein 1	245	0.79
chr3_9609034_9610646	3.56	Zfp704	zinc finger protein 704	245	0.94
chr3_154327918_154328874	3.56	Lhx8	LIM homeobox protein 8	230	0.93
chr16_22162976_22163893	3.55	Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	135	0.96
chr4_155085637_155086611	3.55	Rer1	retention in endoplasmic reticulum sorting receptor 1	247	0.67
chr3_129213694_129214733	3.55	Pitx2	paired-like homeodomain transcription factor 2	62	0.97
chr1_57774668_57775682	3.55	Spats2l	spermatogenesis associated, serine-rich 2-like	258	0.95
chr4_109977849_109978740	3.53	Dmrta2	doublesex and mab-3 related transcription factor like family A2	241	0.73
chr10_67096114_67097344	3.50	Reep3	receptor accessory protein 3	117	0.67
chr6_53067832_53069023	3.50	Jazf1	JAZF zinc finger 1	204	0.95
chr10_43174435_43174840	3.49	9030612E09Rik	RIKEN cDNA 9030612E09 gene	62	0.55
chr2_65238028_65239429	3.49	Cobll1	Cobl-like 1	7	0.5
chr12_117533503_117534508	3.46	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5	117	0.97
chr2_139677053_139678960	3.46	Ism1	isthmin 1, angiogenesis inhibitor	172	0.66
chr5_113993006_113994051	3.45	Ssh1	slingshot protein phosphatase 1	239	0.89
chr9_95405432_95407220	3.45	Chst2	carbohydrate sulfotransferase 2	396	0.73
chr6_122485766_122486276	3.44	Rimklb	ribosomal modification protein rimK-like family member B	418	0.77
chr2_33130296_33131698	3.42	Garnl3	GTPase activating RANGAP domain-like 3	389	0.84
chr9_29412240_29412812	3.42	Ntm	neurotrimin	322	0.95
chr10_81429712_81431957	3.41	Nfic	nuclear factor I/C	171	0.85
chr13_103333732_103334394	3.40	Mast4	microtubule associated serine/threonine kinase family member 4	129	0.97
chr1_38835547_38836894	3.39	Lonrf2	LON peptidase N-terminal domain and ring finger 2	154	0.95
chr13_55471184_55472974	3.39	Mir6944	microRNA 6944	5697	0.08
chr15_87624344_87625037	3.39	Tafa5	TAFA chemokine like family member 5	540	0.87
chr12_22622855_22623610	3.38	Gm40864	predicted gene, 40864	113	0.53
chr9_65140883_65141482	3.37	Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	7	0.97
chr14_57525179_57526034	3.36	Il17d	interleukin 17D	829	0.55
chr17_83214679_83215981	3.36	Pkdcc	protein kinase domain containing, cytoplasmic	38	0.98
chr14_29722466_29722817	3.35	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	777	0.62
chr1_79858099_79859256	3.35	Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	19	0.98
chr18_24708936_24710320	3.34	Fhod3	formin homology 2 domain containing 3	183	0.62
chr9_107709267_107710507	3.34	Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	132	0.92
chr4_105109394_105110039	3.33	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	174	0.97
chr3_125937638_125938666	3.31	Ugt8a	UDP galactosyltransferase 8A	399	0.92
chr7_114116927_114117657	3.30	Rras2	related RAS viral (r-ras) oncogene 2	472	0.85
chr10_31608510_31609170	3.30	Rnf217	ring finger protein 217	344	0.88
chr5_138995205_138996403	3.29	Pdgfa	platelet derived growth factor, alpha	197	0.86
chr5_33995599_33996957	3.29	Nat8l	N-acetyltransferase 8-like	294	0.82
chr6_120492980_120494328	3.29	Tmem121b	transmembrane protein 121B	153	0.93
chr1_6440931_6441627	3.28	Gm19026	predicted gene, 19026	17	0.98
chr1_34750435_34750828	3.27	Arhgef4	Rho guanine nucleotide exchange factor (GEF) 4	50	0.96
chr4_24966254_24966983	3.26	C230012O17Rik	RIKEN cDNA C230012O17 gene	2	0.49
chr7_63757798_63758433	3.26	Otud7a	OTU domain containing 7A	3403	0.22
chr16_17797113_17797920	3.25	Scarf2	scavenger receptor class F, member 2	166	0.9
chr3_18054686_18055378	3.25	Bhlhe22	basic helix-loop-helix family, member e22	858	0.62
chr7_34655144_34655944	3.25	Kctd15	potassium channel tetramerisation domain containing 15	35	0.96
chr2_92599641_92600412	3.24	Chst1	carbohydrate sulfotransferase 1	319	0.85
chr1_14309545_14310115	3.24	Eya1	EYA transcriptional coactivator and phosphatase 1	6	0.99
chr5_5380210_5380890	3.22	Cdk14	cyclin-dependent kinase 14	299	0.92
chr19_61225302_61226760	3.21	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	541	0.67
chr7_65861740_65862468	3.20	Pcsk6	proprotein convertase subtilisin/kexin type 6	32	0.59
chr12_108554869_108555400	3.20	Gm16596	predicted gene, 16596	330	0.55
chr4_66403446_66404232	3.20	Astn2	astrotactin 2	644	0.81
chr13_78198276_78198655	3.20	A830082K12Rik	RIKEN cDNA A830082K12 gene	448	0.5
chr11_114066488_114067724	3.19	Sdk2	sidekick cell adhesion molecule 2	60	0.98
chr4_78211506_78212633	3.18	Ptprd	protein tyrosine phosphatase, receptor type, D	108	0.5
chr13_78198943_78199319	3.17	A830082K12Rik	RIKEN cDNA A830082K12 gene	607	0.42
chr4_119356312_119356627	3.17	Ccdc30	coiled-coil domain containing 30	3333	0.14
chr5_112394543_112395027	3.16	Asphd2	aspartate beta-hydroxylase domain containing 2	81	0.95
chr1_155244126_155244829	3.15	BC034090	cDNA sequence BC034090	33	0.97
chr17_8800581_8801529	3.15	Pde10a	phosphodiesterase 10A	638	0.79
chr10_61783126_61783594	3.15	Macroh2a2	macroH2A.2 histone	787	0.59
chr2_28446566_28447382	3.14	Ppp1r26	protein phosphatase 1, regulatory subunit 26	108	0.95
chr4_149586082_149586582	3.13	Clstn1	calsyntenin 1	136	0.94
chr7_99268137_99268951	3.13	Map6	microtubule-associated protein 6	138	0.92
chr14_65953649_65953813	3.13	Scara3	scavenger receptor class A, member 3	204	0.93
chr9_58822128_58823600	3.13	Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	548	0.82
chr9_72924923_72926161	3.12	Pygo1	pygopus 1	103	0.93
chr2_163202628_163203658	3.12	Tox2	TOX high mobility group box family member 2	18	0.98
chr10_84533171_84534667	3.10	Ckap4	cytoskeleton-associated protein 4	117	0.94
chr1_192854834_192855905	3.09	Sertad4	SERTA domain containing 4	117	0.82
chr5_146384860_146385320	3.09	Wasf3	WAS protein family, member 3	105	0.97
chr2_102451171_102452295	3.08	Fjx1	four jointed box 1	766	0.72
chr7_133121696_133122677	3.07	Ctbp2	C-terminal binding protein 2	14	0.95
chr11_52098162_52099642	3.07	Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	221	0.52
chr3_30507827_30509444	3.06	Mecom	MDS1 and EVI1 complex locus	852	0.52
chr12_26414308_26415459	3.05	Mir6538	microRNA 6538	127	0.66
chr12_107752714_107752867	3.05	4930465M20Rik	RIKEN cDNA 4930465M20 gene	17294	0.23
chr2_158409115_158410592	3.04	Ralgapb	Ral GTPase activating protein, beta subunit (non-catalytic)	0	0.95
chr2_165563196_165563907	3.03	Eya2	EYA transcriptional coactivator and phosphatase 2	31481	0.13
chr18_82169346_82169880	3.03	Gm50294	predicted gene, 50294	88897	0.07
chr3_141464728_141465909	3.03	Gm15688	predicted gene 15688	15	0.59
chr7_112678831_112680131	3.02	Tead1	TEA domain family member 1	29	0.91
chr4_134703673_134704909	3.02	Man1c1	mannosidase, alpha, class 1C, member 1	1	0.98
chr6_119107307_119108229	3.02	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	207	0.96
chr9_87730290_87730964	3.01	Tbx18	T-box18	130	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.6	4.6	GO:0007183	SMAD protein complex assembly(GO:0007183)
3.7	11.2	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
3.5	10.4	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
3.2	9.7	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
2.8	2.8	GO:0003338	metanephros morphogenesis(GO:0003338)
2.7	8.2	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
2.7	8.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
2.6	7.9	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
2.5	2.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
2.4	12.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
2.3	7.0	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
2.2	8.9	GO:0003219	cardiac right ventricle formation(GO:0003219)
2.1	8.6	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
2.1	10.6	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
2.1	6.3	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
2.1	6.3	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
2.0	5.9	GO:0003358	noradrenergic neuron development(GO:0003358)
2.0	5.9	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
1.9	5.7	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
1.9	13.3	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
1.9	5.6	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
1.8	5.5	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
1.8	7.4	GO:0003383	apical constriction(GO:0003383)
1.8	5.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.8	9.1	GO:0061549	sympathetic ganglion development(GO:0061549)
1.8	3.6	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
1.8	5.4	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.8	3.5	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.7	5.2	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.7	1.7	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
1.7	15.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
1.7	1.7	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
1.7	5.0	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
1.7	5.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
1.7	5.0	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
1.7	5.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
1.6	1.6	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
1.6	9.8	GO:0003263	cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264) regulation of secondary heart field cardioblast proliferation(GO:0003266)
1.6	1.6	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.6	4.8	GO:0072193	ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
1.6	6.4	GO:0002175	protein localization to paranode region of axon(GO:0002175)
1.6	7.9	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.5	3.1	GO:0021564	vagus nerve development(GO:0021564)
1.5	1.5	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
1.5	6.1	GO:0035799	ureter maturation(GO:0035799)
1.5	4.5	GO:0071492	cellular response to UV-A(GO:0071492)
1.5	1.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
1.5	4.4	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.4	4.3	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
1.4	4.3	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278)
1.4	1.4	GO:0097374	sensory neuron axon guidance(GO:0097374)
1.4	5.7	GO:0021978	telencephalon regionalization(GO:0021978)
1.4	4.2	GO:0060178	regulation of exocyst localization(GO:0060178)
1.4	5.6	GO:0021631	optic nerve morphogenesis(GO:0021631)
1.4	4.2	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
1.4	2.8	GO:0072107	regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
1.4	9.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
1.4	4.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.4	5.4	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.4	4.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.3	4.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.3	2.7	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.3	6.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
1.3	5.3	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
1.3	2.6	GO:0061642	chemoattraction of axon(GO:0061642)
1.3	3.9	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
1.3	3.9	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
1.3	5.2	GO:0060486	Clara cell differentiation(GO:0060486)
1.3	3.8	GO:0030167	proteoglycan catabolic process(GO:0030167)
1.3	11.4	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.3	1.3	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
1.2	5.0	GO:0061743	motor learning(GO:0061743)
1.2	3.7	GO:0060600	dichotomous subdivision of an epithelial terminal unit(GO:0060600)
1.2	14.9	GO:0043586	tongue development(GO:0043586)
1.2	2.5	GO:0021557	oculomotor nerve development(GO:0021557)
1.2	3.7	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.2	3.7	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
1.2	3.6	GO:1901475	pyruvate transmembrane transport(GO:1901475)
1.2	4.8	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
1.2	7.2	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
1.2	3.6	GO:0001880	Mullerian duct regression(GO:0001880)
1.2	3.6	GO:0045218	zonula adherens maintenance(GO:0045218)
1.2	6.0	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
1.2	1.2	GO:2000823	regulation of androgen receptor activity(GO:2000823)
1.2	3.5	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
1.2	10.5	GO:0051764	actin crosslink formation(GO:0051764)
1.2	1.2	GO:1901203	positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
1.1	3.4	GO:2000591	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
1.1	3.4	GO:0032289	central nervous system myelin formation(GO:0032289)
1.1	3.4	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
1.1	3.4	GO:0086029	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
1.1	3.3	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
1.1	3.3	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.1	4.3	GO:0086064	cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
1.1	2.1	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
1.1	8.5	GO:0046069	cGMP catabolic process(GO:0046069)
1.1	1.1	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
1.0	5.2	GO:0035989	tendon development(GO:0035989)
1.0	3.1	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.0	4.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
1.0	2.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
1.0	4.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
1.0	4.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
1.0	4.1	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
1.0	4.1	GO:0086070	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
1.0	2.0	GO:0003160	endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
1.0	3.0	GO:0035262	gonad morphogenesis(GO:0035262)
1.0	3.0	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
1.0	3.9	GO:0023041	neuronal signal transduction(GO:0023041)
1.0	3.9	GO:2000680	regulation of rubidium ion transport(GO:2000680)
1.0	7.8	GO:0001778	plasma membrane repair(GO:0001778)
1.0	14.6	GO:0060384	innervation(GO:0060384)
1.0	1.9	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.9	2.7	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.9	1.8	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.9	0.9	GO:0072025	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.9	1.8	GO:0032474	otolith morphogenesis(GO:0032474)
0.9	0.9	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.9	3.5	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.9	1.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.9	3.5	GO:0060437	lung growth(GO:0060437)
0.9	0.9	GO:0060066	oviduct development(GO:0060066)
0.9	3.5	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.9	1.7	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.9	2.6	GO:0003207	cardiac chamber formation(GO:0003207)
0.8	0.8	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.8	3.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.8	2.5	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.8	2.5	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.8	1.7	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.8	3.3	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.8	2.5	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.8	2.5	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.8	0.8	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.8	0.8	GO:0060685	regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.8	4.9	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.8	0.8	GO:0045136	development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.8	2.4	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.8	2.4	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.8	3.1	GO:0051639	actin filament network formation(GO:0051639)
0.8	3.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.8	1.6	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.8	1.5	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.8	4.6	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.8	2.3	GO:0001927	exocyst assembly(GO:0001927)
0.8	3.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.8	0.8	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.8	3.8	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.7	5.2	GO:0018158	protein oxidation(GO:0018158)
0.7	0.7	GO:1903984	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7	6.7	GO:0021859	pyramidal neuron differentiation(GO:0021859)
0.7	3.0	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.7	1.5	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.7	1.5	GO:0007403	glial cell fate determination(GO:0007403)
0.7	2.2	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.7	2.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.7	2.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.7	1.4	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.7	2.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.7	4.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.7	1.4	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.7	19.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.7	2.8	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.7	1.4	GO:0072104	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.7	4.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.7	3.4	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7	6.9	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.7	2.0	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.7	2.0	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.7	2.7	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.7	2.7	GO:0060914	heart formation(GO:0060914)
0.7	2.0	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.7	2.0	GO:0003163	sinoatrial node development(GO:0003163)
0.7	1.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.7	6.7	GO:0060013	righting reflex(GO:0060013)
0.7	12.0	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.7	6.6	GO:0021854	hypothalamus development(GO:0021854)
0.7	2.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.7	1.3	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.7	5.2	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.6	2.6	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6	1.9	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.6	1.9	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.6	1.9	GO:0097503	sialylation(GO:0097503)
0.6	1.9	GO:0032252	secretory granule localization(GO:0032252)
0.6	1.9	GO:1990035	calcium ion import into cell(GO:1990035)
0.6	1.3	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.6	1.9	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.6	4.4	GO:0099515	actin filament-based transport(GO:0099515)
0.6	1.9	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.6	1.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6	3.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.6	1.9	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6	4.3	GO:0035878	nail development(GO:0035878)
0.6	0.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.6	2.5	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.6	1.8	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.6	1.2	GO:0021826	substrate-independent telencephalic tangential migration(GO:0021826) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.6	0.6	GO:0007494	midgut development(GO:0007494)
0.6	1.8	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.6	4.9	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.6	3.1	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.6	1.2	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.6	1.2	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.6	1.8	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.6	0.6	GO:0060129	corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.6	1.8	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.6	7.8	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.6	3.6	GO:0070314	G1 to G0 transition(GO:0070314)
0.6	2.4	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.6	3.6	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.6	3.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.6	1.8	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.6	1.2	GO:0098828	modulation of inhibitory postsynaptic potential(GO:0098828)
0.6	4.7	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.6	1.8	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.6	4.1	GO:0021884	forebrain neuron development(GO:0021884)
0.6	1.2	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.6	3.5	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6	7.0	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6	2.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.6	5.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.6	5.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.6	1.7	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.6	1.7	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.6	1.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.6	9.6	GO:0001964	startle response(GO:0001964)
0.6	2.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6	1.7	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.6	2.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.5	3.8	GO:0071625	vocalization behavior(GO:0071625)
0.5	30.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.5	1.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.5	2.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.5	0.5	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.5	2.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.5	0.5	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.5	1.6	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.5	5.3	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.5	1.0	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.5	0.5	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.5	1.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.5	0.5	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.5	2.6	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.5	4.6	GO:0001709	cell fate determination(GO:0001709)
0.5	3.1	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5	1.5	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.5	1.5	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.5	1.5	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.5	5.5	GO:0045606	positive regulation of epidermal cell differentiation(GO:0045606)
0.5	1.5	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
0.5	2.0	GO:0051697	protein delipidation(GO:0051697)
0.5	3.9	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.5	3.9	GO:0006013	mannose metabolic process(GO:0006013)
0.5	0.5	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.5	1.0	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5	1.9	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.5	1.9	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.5	1.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.5	0.5	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.5	1.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.5	2.4	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.5	1.9	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.5	1.4	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5	2.9	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.5	0.5	GO:0048143	astrocyte activation(GO:0048143)
0.5	3.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.5	0.5	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.5	0.9	GO:0030035	microspike assembly(GO:0030035)
0.5	0.9	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.5	5.6	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.5	1.9	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.5	0.5	GO:0072205	metanephric collecting duct development(GO:0072205)
0.5	1.8	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.5	2.3	GO:0046836	glycolipid transport(GO:0046836)
0.5	1.4	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.5	0.5	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.5	0.9	GO:0065001	specification of axis polarity(GO:0065001)
0.4	1.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.4	2.2	GO:0030578	PML body organization(GO:0030578)
0.4	1.3	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.4	1.3	GO:0071316	cellular response to nicotine(GO:0071316)
0.4	4.0	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.4	1.8	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.4	7.0	GO:0010842	retina layer formation(GO:0010842)
0.4	1.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4	2.2	GO:0035902	response to immobilization stress(GO:0035902)
0.4	2.6	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.4	1.3	GO:0035106	operant conditioning(GO:0035106)
0.4	0.9	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.4	3.9	GO:0003334	keratinocyte development(GO:0003334)
0.4	1.7	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.4	0.4	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.4	1.3	GO:0045759	negative regulation of action potential(GO:0045759)
0.4	1.3	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.4	0.8	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.4	1.3	GO:0002930	trabecular meshwork development(GO:0002930)
0.4	2.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4	0.4	GO:0060594	mammary gland specification(GO:0060594)
0.4	1.2	GO:0021554	optic nerve development(GO:0021554)
0.4	3.3	GO:0031643	positive regulation of myelination(GO:0031643)
0.4	1.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.4	0.4	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.4	0.4	GO:0060166	olfactory pit development(GO:0060166)
0.4	4.1	GO:0007135	meiosis II(GO:0007135)
0.4	0.8	GO:0051794	regulation of catagen(GO:0051794)
0.4	0.8	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.4	2.0	GO:0099623	regulation of cardiac muscle cell membrane repolarization(GO:0099623)
0.4	2.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.4	1.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4	0.8	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.4	0.8	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.4	3.5	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4	1.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.4	0.8	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.4	2.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4	1.9	GO:1904424	regulation of GTP binding(GO:1904424)
0.4	0.8	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.4	0.4	GO:0032532	regulation of microvillus length(GO:0032532)
0.4	0.8	GO:0071895	odontoblast differentiation(GO:0071895)
0.4	10.1	GO:0001755	neural crest cell migration(GO:0001755)
0.4	1.5	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4	0.7	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.4	3.0	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4	2.2	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.4	0.7	GO:2001023	regulation of response to drug(GO:2001023)
0.4	5.5	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.4	0.7	GO:0060973	cell migration involved in heart development(GO:0060973)
0.4	0.7	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.4	1.5	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.4	1.8	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.4	0.4	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.4	1.8	GO:0061377	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.4	1.5	GO:0060004	reflex(GO:0060004)
0.4	0.7	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.4	0.4	GO:0003289	septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.4	1.1	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.4	1.4	GO:0030091	protein repair(GO:0030091)
0.4	1.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.3	0.7	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.3	1.0	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.3	1.4	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.3	1.4	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.3	2.4	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3	0.7	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.3	1.7	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.3	1.7	GO:0070842	aggresome assembly(GO:0070842)
0.3	2.0	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3	1.0	GO:0071873	response to norepinephrine(GO:0071873)
0.3	1.3	GO:0034698	response to gonadotropin(GO:0034698) cellular response to gonadotropin stimulus(GO:0071371)
0.3	1.0	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3	1.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.3	1.3	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.3	0.7	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.3	2.3	GO:0060068	vagina development(GO:0060068)
0.3	2.0	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3	1.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.3	2.6	GO:0006012	galactose metabolic process(GO:0006012)
0.3	0.3	GO:0051938	L-glutamate import(GO:0051938)
0.3	0.3	GO:1904238	pericyte cell differentiation(GO:1904238)
0.3	2.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3	0.3	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.3	0.3	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.3	2.6	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3	1.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.3	1.3	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.3	1.3	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.3	1.3	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.3	1.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.3	1.3	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.3	0.6	GO:0016264	gap junction assembly(GO:0016264)
0.3	1.9	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.3	0.9	GO:0060017	parathyroid gland development(GO:0060017)
0.3	3.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.3	0.9	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.3	0.3	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.3	0.3	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3	3.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.3	0.9	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.3	0.6	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.3	1.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3	3.4	GO:0002329	pre-B cell differentiation(GO:0002329)
0.3	0.6	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3	1.2	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3	0.6	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.3	1.2	GO:0042118	endothelial cell activation(GO:0042118)
0.3	0.3	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.3	0.6	GO:1904528	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.3	0.3	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.3	2.4	GO:0060065	uterus development(GO:0060065)
0.3	0.6	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.3	0.9	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.3	0.6	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.3	0.9	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3	0.6	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3	1.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.3	2.0	GO:0097062	dendritic spine maintenance(GO:0097062)
0.3	2.6	GO:0001780	neutrophil homeostasis(GO:0001780)
0.3	0.9	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.3	0.6	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3	0.6	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.3	1.4	GO:0060081	membrane hyperpolarization(GO:0060081)
0.3	1.7	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3	0.3	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.3	0.3	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3	2.8	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.3	0.6	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.3	0.3	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.3	0.8	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
0.3	1.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3	0.8	GO:0048665	neuron fate specification(GO:0048665)
0.3	18.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	2.2	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.3	0.8	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.3	2.8	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3	0.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3	1.6	GO:0051775	response to redox state(GO:0051775)
0.3	1.9	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.3	0.3	GO:0051464	positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
0.3	0.8	GO:0072318	clathrin coat disassembly(GO:0072318)
0.3	0.3	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.3	2.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.3	3.6	GO:0010954	positive regulation of protein processing(GO:0010954)
0.3	0.8	GO:0032439	endosome localization(GO:0032439)
0.3	0.3	GO:0021559	trigeminal nerve development(GO:0021559)
0.3	1.0	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.3	0.3	GO:0006667	sphinganine metabolic process(GO:0006667)
0.3	0.5	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.3	0.3	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.3	0.5	GO:2001053	regulation of mesenchymal cell apoptotic process(GO:2001053)
0.3	1.0	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.2	0.5	GO:0045112	integrin biosynthetic process(GO:0045112)
0.2	1.7	GO:0046541	saliva secretion(GO:0046541)
0.2	0.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.2	0.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.2	0.2	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.2	0.5	GO:0010288	response to lead ion(GO:0010288)
0.2	0.7	GO:0021871	forebrain regionalization(GO:0021871)
0.2	1.0	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.2	1.0	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.2	1.2	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.2	0.7	GO:1902805	positive regulation of synaptic vesicle transport(GO:1902805)
0.2	1.2	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.2	0.5	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2	0.2	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.2	0.7	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2	1.2	GO:0072675	osteoclast fusion(GO:0072675)
0.2	0.9	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.2	0.2	GO:0060435	bronchiole development(GO:0060435)
0.2	0.7	GO:0060468	prevention of polyspermy(GO:0060468)
0.2	1.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2	23.0	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.2	0.9	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2	0.9	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.2	0.9	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2	0.7	GO:0016081	synaptic vesicle docking(GO:0016081)
0.2	0.2	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.2	0.4	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.2	3.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2	0.7	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2	6.7	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2	1.3	GO:0035641	locomotory exploration behavior(GO:0035641)
0.2	7.1	GO:0019226	transmission of nerve impulse(GO:0019226)
0.2	0.7	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2	0.2	GO:0048318	axial mesoderm development(GO:0048318)
0.2	2.6	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2	0.2	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.2	0.7	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2	0.6	GO:0015888	thiamine transport(GO:0015888)
0.2	0.9	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	1.5	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.2	0.4	GO:0018992	germ-line sex determination(GO:0018992)
0.2	0.6	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.2	1.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.2	0.6	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.2	0.4	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2	0.4	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.2	1.5	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.2	1.9	GO:0016082	synaptic vesicle priming(GO:0016082)
0.2	0.8	GO:0016266	O-glycan processing(GO:0016266)
0.2	1.7	GO:0018095	protein polyglutamylation(GO:0018095)
0.2	1.2	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.2	1.2	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2	0.8	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.2	2.5	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.2	0.2	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.2	1.0	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.2	0.6	GO:0015705	iodide transport(GO:0015705)
0.2	0.2	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.2	0.8	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887)
0.2	0.6	GO:1902075	cellular response to salt(GO:1902075)
0.2	0.4	GO:0022605	oogenesis stage(GO:0022605)
0.2	0.6	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2	0.4	GO:0046909	intermembrane transport(GO:0046909)
0.2	1.4	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.2	0.6	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2	0.2	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2	0.4	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.2	0.4	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2	0.8	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.2	1.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	0.6	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.2	0.6	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.6	GO:0014842	regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.2	0.2	GO:0045990	carbon catabolite regulation of transcription(GO:0045990)
0.2	0.4	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.2	1.5	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.2	0.6	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.2	0.9	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	0.4	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.2	0.2	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	1.1	GO:0003091	renal water homeostasis(GO:0003091)
0.2	1.3	GO:0031000	response to caffeine(GO:0031000)
0.2	1.3	GO:0048663	neuron fate commitment(GO:0048663)
0.2	0.4	GO:0001757	somite specification(GO:0001757)
0.2	2.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	0.5	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	0.4	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2	0.4	GO:0061055	myotome development(GO:0061055)
0.2	1.4	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.2	0.4	GO:0048484	enteric nervous system development(GO:0048484)
0.2	0.2	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2	0.4	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	1.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.2	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.2	0.2	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2	0.5	GO:0030070	insulin processing(GO:0030070)
0.2	0.2	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2	0.2	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.2	0.5	GO:1904970	brush border assembly(GO:1904970)
0.2	0.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	1.0	GO:0032060	bleb assembly(GO:0032060)
0.2	0.8	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.2	0.7	GO:0071318	cellular response to ATP(GO:0071318)
0.2	0.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.2	0.2	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.2	1.0	GO:0048566	embryonic digestive tract development(GO:0048566)
0.2	0.3	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.2	0.3	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.2	1.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	1.9	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2	1.0	GO:0006621	protein retention in ER lumen(GO:0006621)
0.2	0.5	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.2	0.3	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2	1.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.2	0.3	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.2	0.6	GO:0051451	myoblast migration(GO:0051451)
0.2	0.8	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2	0.3	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.2	2.0	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.2	2.8	GO:0015701	bicarbonate transport(GO:0015701)
0.2	0.5	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2	0.3	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.2	0.2	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2	0.5	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.2	1.4	GO:0035428	hexose transmembrane transport(GO:0035428)
0.2	0.8	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.2	1.5	GO:1990403	embryonic brain development(GO:1990403)
0.2	0.8	GO:0036035	osteoclast development(GO:0036035)
0.2	0.2	GO:0090383	phagosome acidification(GO:0090383)
0.2	3.8	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.2	0.3	GO:2000679	positive regulation of transcription regulatory region DNA binding(GO:2000679)
0.2	0.5	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.2	1.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.2	0.8	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2	0.3	GO:1904396	regulation of neuromuscular junction development(GO:1904396)
0.2	1.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.2	0.9	GO:0009404	toxin metabolic process(GO:0009404)
0.2	6.5	GO:0009410	response to xenobiotic stimulus(GO:0009410)
0.1	0.6	GO:0015808	L-alanine transport(GO:0015808)
0.1	2.4	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.7	GO:0007614	short-term memory(GO:0007614)
0.1	0.1	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1	0.6	GO:0060481	lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1	0.3	GO:0045655	regulation of monocyte differentiation(GO:0045655)
0.1	0.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.4	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.1	GO:0033058	directional locomotion(GO:0033058)
0.1	0.7	GO:0090042	tubulin deacetylation(GO:0090042)
0.1	0.1	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
0.1	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.1	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	0.1	GO:0072053	renal inner medulla development(GO:0072053)
0.1	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.1	0.3	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1	0.3	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.4	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.1	1.2	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.5	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.1	0.3	GO:0060179	male mating behavior(GO:0060179)
0.1	0.4	GO:0042637	catagen(GO:0042637)
0.1	0.7	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	9.4	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.1	0.1	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.1	0.4	GO:0070587	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1	0.1	GO:0042097	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.1	0.4	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.1	0.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	2.4	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.5	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.1	0.9	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.4	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	1.1	GO:0035094	response to nicotine(GO:0035094)
0.1	0.7	GO:0030575	nuclear body organization(GO:0030575)
0.1	0.4	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.1	2.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.1	2.1	GO:0071475	cellular response to salt stress(GO:0071472) cellular hyperosmotic salinity response(GO:0071475)
0.1	0.4	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.1	0.6	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	0.1	GO:0003171	atrioventricular valve development(GO:0003171)
0.1	0.1	GO:0090135	actin filament branching(GO:0090135)
0.1	0.9	GO:0001658	branching involved in ureteric bud morphogenesis(GO:0001658)
0.1	0.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	2.0	GO:0009268	response to pH(GO:0009268)
0.1	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.1	1.8	GO:0002385	mucosal immune response(GO:0002385)
0.1	1.4	GO:0034389	lipid particle organization(GO:0034389)
0.1	0.2	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1	0.2	GO:0070673	response to interleukin-18(GO:0070673) cellular response to interleukin-18(GO:0071351)
0.1	0.2	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.1	0.7	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	3.8	GO:0015914	phospholipid transport(GO:0015914)
0.1	3.5	GO:0042472	inner ear morphogenesis(GO:0042472)
0.1	0.5	GO:0060033	anatomical structure regression(GO:0060033)
0.1	0.9	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.1	0.3	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.1	1.9	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.1	0.2	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.1	0.2	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.2	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.1	0.1	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	0.1	GO:0072017	distal tubule development(GO:0072017)
0.1	0.2	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.6	GO:0071168	protein localization to chromatin(GO:0071168)
0.1	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.2	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.2	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.1	0.1	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1	0.2	GO:0030913	paranodal junction assembly(GO:0030913)
0.1	1.6	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.1	0.1	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1	0.1	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.1	0.3	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.2	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	0.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.1	GO:0048486	parasympathetic nervous system development(GO:0048486)
0.1	0.2	GO:1900368	regulation of RNA interference(GO:1900368)
0.1	0.3	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	2.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	1.5	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.3	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1	0.3	GO:1903232	melanosome assembly(GO:1903232)
0.1	1.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.4	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
0.1	0.1	GO:0090237	regulation of arachidonic acid secretion(GO:0090237)
0.1	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	0.1	GO:0072044	collecting duct development(GO:0072044)
0.1	0.3	GO:0043084	penile erection(GO:0043084)
0.1	0.6	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.1	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.2	GO:0043217	myelin maintenance(GO:0043217)
0.1	0.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.1	0.3	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	0.5	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.1	0.3	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.1	0.1	GO:0010255	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1	0.8	GO:0048706	embryonic skeletal system development(GO:0048706)
0.1	0.4	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.1	GO:0060023	soft palate development(GO:0060023)
0.1	0.4	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.1	0.3	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.1	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1	0.2	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.1	0.7	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.1	2.3	GO:0031424	keratinization(GO:0031424)
0.1	0.2	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.1	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	1.7	GO:0007405	neuroblast proliferation(GO:0007405)
0.1	0.2	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.4	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.1	1.4	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.1	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.5	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.5	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	0.3	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.6	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.8	GO:0042670	retinal cone cell differentiation(GO:0042670)
0.1	4.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	3.8	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	0.2	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.1	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.2	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	0.1	GO:0051797	regulation of hair follicle development(GO:0051797)
0.1	0.2	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.1	GO:0071220	response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.1	0.4	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.1	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.7	GO:0042417	dopamine metabolic process(GO:0042417)
0.1	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.4	GO:0042359	vitamin D metabolic process(GO:0042359)
0.1	0.1	GO:0021545	cranial nerve development(GO:0021545)
0.1	0.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.2	GO:1990928	response to amino acid starvation(GO:1990928)
0.1	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	0.1	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.1	0.7	GO:0008210	estrogen metabolic process(GO:0008210)
0.1	0.1	GO:0042471	ear morphogenesis(GO:0042471)
0.1	0.2	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.1	0.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.1	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1	1.1	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.3	GO:0042481	regulation of odontogenesis(GO:0042481)
0.1	0.2	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.1	GO:0097278	complement-dependent cytotoxicity(GO:0097278)
0.1	1.9	GO:0060828	regulation of canonical Wnt signaling pathway(GO:0060828)
0.1	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.1	GO:0048769	sarcomerogenesis(GO:0048769)
0.1	0.6	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.8	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	1.2	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.1	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.3	GO:0030903	notochord development(GO:0030903)
0.1	0.8	GO:0042755	eating behavior(GO:0042755)
0.1	0.2	GO:0030222	eosinophil differentiation(GO:0030222)
0.1	0.1	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
0.1	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.1	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.1	0.2	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.1	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.2	GO:0048546	digestive tract morphogenesis(GO:0048546)
0.1	0.2	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.1	0.1	GO:0010635	regulation of mitochondrial fusion(GO:0010635)
0.1	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.1	0.1	GO:0060347	heart trabecula formation(GO:0060347)
0.1	0.5	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	0.1	GO:0008078	mesodermal cell migration(GO:0008078)
0.1	0.2	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.1	0.3	GO:0009880	embryonic pattern specification(GO:0009880)
0.1	0.1	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.1	0.3	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.1	GO:0007379	segment specification(GO:0007379)
0.1	0.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0033504	floor plate development(GO:0033504)
0.1	0.1	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1	0.7	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.2	GO:0042851	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
0.1	0.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.6	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.1	0.1	GO:0046103	inosine biosynthetic process(GO:0046103)
0.1	0.1	GO:0003356	regulation of cilium beat frequency(GO:0003356)
0.1	0.1	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1	0.9	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.4	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	0.1	GO:0072087	renal vesicle development(GO:0072087)
0.1	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1	0.2	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.3	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.3	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	1.0	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.4	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	1.3	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.0	GO:0001768	establishment of lymphocyte polarity(GO:0001767) establishment of T cell polarity(GO:0001768)
0.0	0.6	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.3	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.3	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.0	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:1903012	positive regulation of bone development(GO:1903012)
0.0	0.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.2	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.2	GO:0042048	olfactory behavior(GO:0042048)
0.0	0.4	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	2.2	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.6	GO:0010524	positive regulation of calcium ion transport into cytosol(GO:0010524)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:2000449	regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0010522	regulation of calcium ion transport into cytosol(GO:0010522)
0.0	0.3	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.3	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.5	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.2	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.2	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0	0.3	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.2	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.4	GO:0030262	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0	0.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0097028	dendritic cell differentiation(GO:0097028)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.1	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.3	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.0	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.2	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196)
0.0	0.1	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.4	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.0	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	2.4	GO:0007601	visual perception(GO:0007601)
0.0	0.2	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.4	GO:0048565	digestive tract development(GO:0048565)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0060290	transdifferentiation(GO:0060290)
0.0	0.0	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534)
0.0	0.0	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.4	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.1	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	0.2	GO:0032963	collagen metabolic process(GO:0032963)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821) peristalsis(GO:0030432)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.0	GO:0018377	protein myristoylation(GO:0018377)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.1	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.1	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0045837	negative regulation of membrane potential(GO:0045837)
0.0	0.0	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0046379	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0	0.1	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.4	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:2000855	mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0	0.0	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085)
0.0	0.1	GO:0002922	positive regulation of humoral immune response(GO:0002922)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0009992	cellular water homeostasis(GO:0009992)
0.0	0.1	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.0	0.0	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.0	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.2	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.0	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.1	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.0	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.0	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.0	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0	0.0	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.0	0.0	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.4	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.3	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0032196	transposition(GO:0032196)
0.0	0.0	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.0	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.0	GO:0044704	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.0	0.0	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0	0.0	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	2.8	GO:0097470	ribbon synapse(GO:0097470)
1.8	1.8	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
1.8	10.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
1.6	4.9	GO:1990597	AIP1-IRE1 complex(GO:1990597)
1.4	4.1	GO:0097427	microtubule bundle(GO:0097427)
1.3	5.3	GO:0033269	internode region of axon(GO:0033269)
1.3	3.9	GO:0043259	laminin-10 complex(GO:0043259)
1.1	3.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
1.0	2.9	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
1.0	3.9	GO:0032437	cuticular plate(GO:0032437)
0.9	4.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.9	0.9	GO:0005606	laminin-1 complex(GO:0005606)
0.8	1.7	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.8	4.2	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.8	14.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.8	9.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8	4.0	GO:0043083	synaptic cleft(GO:0043083)
0.8	2.4	GO:0005610	laminin-5 complex(GO:0005610)
0.8	3.1	GO:0071953	elastic fiber(GO:0071953)
0.8	3.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.8	2.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.8	0.8	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.8	4.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.8	12.8	GO:0030673	axolemma(GO:0030673)
0.7	21.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.7	14.9	GO:0048786	presynaptic active zone(GO:0048786)
0.7	2.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.7	2.1	GO:0072534	perineuronal net(GO:0072534)
0.7	8.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.7	2.7	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.6	4.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6	1.9	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6	0.6	GO:0097418	neurofibrillary tangle(GO:0097418)
0.6	1.2	GO:0043511	inhibin complex(GO:0043511)
0.6	10.4	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6	5.1	GO:0043194	axon initial segment(GO:0043194)
0.6	36.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.5	0.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.5	1.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.5	4.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.5	1.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	3.1	GO:0005915	zonula adherens(GO:0005915)
0.5	1.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5	1.9	GO:0032021	NELF complex(GO:0032021)
0.5	2.9	GO:0001674	female germ cell nucleus(GO:0001674)
0.5	2.8	GO:0030314	junctional membrane complex(GO:0030314)
0.5	11.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.5	1.9	GO:1990357	terminal web(GO:1990357)
0.5	1.8	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4	6.7	GO:0031045	dense core granule(GO:0031045)
0.4	4.5	GO:0001527	microfibril(GO:0001527)
0.4	3.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.4	5.8	GO:0034704	calcium channel complex(GO:0034704)
0.4	1.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.4	2.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.4	5.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.4	13.7	GO:0042734	presynaptic membrane(GO:0042734)
0.4	2.4	GO:0001652	granular component(GO:0001652)
0.4	0.8	GO:0005899	insulin receptor complex(GO:0005899)
0.4	1.6	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.4	32.9	GO:0005604	basement membrane(GO:0005604)
0.4	1.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.4	2.0	GO:0033268	node of Ranvier(GO:0033268)
0.4	4.7	GO:0031512	motile primary cilium(GO:0031512)
0.4	3.0	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.4	1.1	GO:0005914	spot adherens junction(GO:0005914)
0.4	0.4	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.3	1.4	GO:0030478	actin cap(GO:0030478)
0.3	3.0	GO:0002116	semaphorin receptor complex(GO:0002116)
0.3	2.3	GO:0032584	growth cone membrane(GO:0032584)
0.3	44.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.3	1.3	GO:0005593	FACIT collagen trimer(GO:0005593)
0.3	1.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.3	1.6	GO:0045098	type III intermediate filament(GO:0045098)
0.3	2.8	GO:1990023	mitotic spindle midzone(GO:1990023)
0.3	3.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	1.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	57.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.3	1.2	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.3	8.7	GO:0005581	collagen trimer(GO:0005581)
0.3	0.6	GO:0016939	kinesin II complex(GO:0016939)
0.3	1.4	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3	1.7	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.3	5.6	GO:0005922	connexon complex(GO:0005922)
0.3	0.8	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.3	2.4	GO:0031527	filopodium membrane(GO:0031527)
0.3	3.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	0.8	GO:1990696	USH2 complex(GO:1990696)
0.3	0.5	GO:1990635	proximal dendrite(GO:1990635)
0.3	2.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.3	3.8	GO:0046930	pore complex(GO:0046930)
0.3	0.5	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.3	1.8	GO:0031209	SCAR complex(GO:0031209)
0.2	12.8	GO:0031012	extracellular matrix(GO:0031012)
0.2	12.7	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2	0.5	GO:0032432	actin filament bundle(GO:0032432)
0.2	1.2	GO:0031983	vesicle lumen(GO:0031983)
0.2	2.9	GO:0000145	exocyst(GO:0000145)
0.2	0.9	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.2	1.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	26.9	GO:0031225	anchored component of membrane(GO:0031225)
0.2	0.6	GO:0033010	paranodal junction(GO:0033010)
0.2	1.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.2	5.1	GO:0031901	early endosome membrane(GO:0031901)
0.2	1.3	GO:0060091	kinocilium(GO:0060091)
0.2	16.4	GO:0043204	perikaryon(GO:0043204)
0.2	0.9	GO:0000137	Golgi cis cisterna(GO:0000137)
0.2	0.6	GO:0045298	tubulin complex(GO:0045298)
0.2	2.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2	2.6	GO:0030175	filopodium(GO:0030175)
0.2	0.5	GO:0044294	dendritic growth cone(GO:0044294)
0.2	0.5	GO:0097443	sorting endosome(GO:0097443)
0.2	0.3	GO:0071203	WASH complex(GO:0071203)
0.2	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	2.7	GO:0031594	neuromuscular junction(GO:0031594)
0.2	4.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.2	0.6	GO:0031143	pseudopodium(GO:0031143)
0.1	4.9	GO:0030315	T-tubule(GO:0030315)
0.1	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	9.7	GO:0030027	lamellipodium(GO:0030027)
0.1	1.4	GO:0032589	neuron projection membrane(GO:0032589)
0.1	0.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	1.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	7.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.3	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.6	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.9	GO:0042587	glycogen granule(GO:0042587)
0.1	7.3	GO:0005884	actin filament(GO:0005884)
0.1	8.4	GO:0043296	apical junction complex(GO:0043296)
0.1	0.4	GO:0044194	cytolytic granule(GO:0044194)
0.1	0.9	GO:0005861	troponin complex(GO:0005861)
0.1	9.9	GO:0070382	exocytic vesicle(GO:0070382)
0.1	3.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.5	GO:0071547	piP-body(GO:0071547)
0.1	1.0	GO:0005771	multivesicular body(GO:0005771)
0.1	0.7	GO:0045179	apical cortex(GO:0045179)
0.1	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.3	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1	0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.3	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.2	GO:0043203	axon hillock(GO:0043203)
0.1	0.5	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.7	GO:0036156	inner dynein arm(GO:0036156)
0.1	1.2	GO:0001741	XY body(GO:0001741)
0.1	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.3	GO:0005916	fascia adherens(GO:0005916)
0.1	1.5	GO:0042383	sarcolemma(GO:0042383)
0.1	0.3	GO:0061574	ASAP complex(GO:0061574)
0.1	0.6	GO:0036157	outer dynein arm(GO:0036157)
0.1	0.1	GO:0042629	mast cell granule(GO:0042629)
0.1	1.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	3.2	GO:0001533	cornified envelope(GO:0001533)
0.1	60.0	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	0.3	GO:0031526	brush border membrane(GO:0031526)
0.1	0.2	GO:1990393	3M complex(GO:1990393)
0.1	0.1	GO:0070160	occluding junction(GO:0070160)
0.1	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.3	GO:0071546	pi-body(GO:0071546)
0.1	0.7	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.2	GO:0032009	early phagosome(GO:0032009)
0.1	0.3	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	0.2	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	47.8	GO:0005615	extracellular space(GO:0005615)
0.1	0.2	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:1990716	axonemal central apparatus(GO:1990716)
0.0	155.6	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.4	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	1.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	1.2	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0	1.8	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.4	GO:0035371	microtubule plus-end(GO:0035371)
0.0	8.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.2	GO:0098802	plasma membrane receptor complex(GO:0098802)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	9.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.9	5.8	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
1.8	5.5	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
1.7	5.2	GO:0048763	calcium-induced calcium release activity(GO:0048763)
1.6	4.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
1.6	6.3	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.5	4.6	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
1.5	2.9	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
1.4	5.7	GO:0005042	netrin receptor activity(GO:0005042)
1.4	4.2	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
1.3	6.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.3	3.9	GO:0097109	neuroligin family protein binding(GO:0097109)
1.3	3.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
1.3	5.0	GO:0032051	clathrin light chain binding(GO:0032051)
1.2	7.5	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
1.2	3.7	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.2	3.6	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.2	3.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.2	4.8	GO:0098821	BMP receptor activity(GO:0098821)
1.2	3.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
1.2	3.5	GO:0030553	cGMP binding(GO:0030553)
1.1	3.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.0	5.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
1.0	3.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
1.0	3.1	GO:0031708	endothelin B receptor binding(GO:0031708)
1.0	10.1	GO:0004016	adenylate cyclase activity(GO:0004016)
1.0	3.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.0	5.7	GO:0038132	neuregulin binding(GO:0038132)
0.9	28.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.9	2.8	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.9	13.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.9	23.7	GO:0045499	chemorepellent activity(GO:0045499)
0.9	3.6	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.9	2.7	GO:0070051	fibrinogen binding(GO:0070051)
0.9	3.6	GO:0070052	collagen V binding(GO:0070052)
0.9	4.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.9	2.6	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.9	1.8	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.9	2.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.9	10.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.8	3.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.8	2.5	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.8	5.8	GO:0003680	AT DNA binding(GO:0003680)
0.8	2.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.8	2.4	GO:0097108	hedgehog family protein binding(GO:0097108)
0.8	3.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.8	23.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.8	22.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.8	3.9	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8	2.3	GO:0035939	microsatellite binding(GO:0035939)
0.7	3.7	GO:0048495	Roundabout binding(GO:0048495)
0.7	5.1	GO:0043495	protein anchor(GO:0043495)
0.7	10.9	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.7	8.8	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.7	2.7	GO:0034056	estrogen response element binding(GO:0034056)
0.7	2.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7	3.3	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.6	3.2	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.6	5.2	GO:0070097	delta-catenin binding(GO:0070097)
0.6	19.8	GO:0005109	frizzled binding(GO:0005109)
0.6	3.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6	10.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.6	1.8	GO:0033142	progesterone receptor binding(GO:0033142)
0.6	1.8	GO:0045504	dynein heavy chain binding(GO:0045504)
0.6	0.6	GO:0031014	troponin T binding(GO:0031014)
0.6	1.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.6	1.8	GO:0030284	estrogen receptor activity(GO:0030284)
0.6	2.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.6	6.4	GO:0070700	BMP receptor binding(GO:0070700)
0.6	7.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.6	2.9	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.6	2.3	GO:0017089	glycolipid transporter activity(GO:0017089)
0.6	9.5	GO:0005112	Notch binding(GO:0005112)
0.6	1.7	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.6	2.2	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.6	2.8	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.5	10.4	GO:0004890	GABA-A receptor activity(GO:0004890)
0.5	1.1	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.5	2.7	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.5	2.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.5	2.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.5	5.9	GO:0005522	profilin binding(GO:0005522)
0.5	2.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5	2.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.5	1.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.5	1.6	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.5	6.3	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.5	3.6	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.5	1.6	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.5	1.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5	2.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.5	17.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.5	1.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.5	1.5	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.5	5.4	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5	3.4	GO:0008932	lytic endotransglycosylase activity(GO:0008932)
0.5	1.9	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.5	0.9	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.5	1.9	GO:0070411	I-SMAD binding(GO:0070411)
0.5	6.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	13.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5	1.8	GO:0051434	BH3 domain binding(GO:0051434)
0.5	1.4	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.5	3.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.4	1.3	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.4	4.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.4	1.3	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.4	5.3	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4	1.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.4	3.9	GO:0045294	alpha-catenin binding(GO:0045294)
0.4	16.9	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.4	1.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.4	2.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.4	4.9	GO:0031005	filamin binding(GO:0031005)
0.4	1.6	GO:0004969	histamine receptor activity(GO:0004969)
0.4	5.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.4	2.8	GO:0005003	ephrin receptor activity(GO:0005003)
0.4	2.0	GO:0004994	somatostatin receptor activity(GO:0004994)
0.4	5.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.4	16.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.4	1.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.4	2.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.4	5.4	GO:0005243	gap junction channel activity(GO:0005243)
0.4	1.5	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4	1.9	GO:0004111	creatine kinase activity(GO:0004111)
0.4	0.8	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.4	1.5	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.4	1.9	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.4	4.5	GO:0015026	coreceptor activity(GO:0015026)
0.4	1.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.4	1.5	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4	7.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.4	5.8	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.4	2.8	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.4	1.8	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.4	11.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.3	6.6	GO:0003785	actin monomer binding(GO:0003785)
0.3	1.4	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3	3.8	GO:0015643	toxic substance binding(GO:0015643)
0.3	3.4	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3	1.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.3	3.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3	3.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	2.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.3	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.3	2.3	GO:0008301	DNA binding, bending(GO:0008301)
0.3	0.3	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.3	0.6	GO:0070698	type I activin receptor binding(GO:0070698)
0.3	2.6	GO:0001972	retinoic acid binding(GO:0001972)
0.3	4.8	GO:0022840	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.3	1.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.3	3.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.3	71.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3	1.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.3	9.5	GO:0070888	E-box binding(GO:0070888)
0.3	0.9	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	29.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.3	2.6	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3	1.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3	1.7	GO:0043121	neurotrophin binding(GO:0043121)
0.3	0.3	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.3	4.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.3	2.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.3	0.8	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3	1.9	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.3	1.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.3	2.7	GO:0071837	HMG box domain binding(GO:0071837)
0.3	1.1	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3	0.8	GO:0051373	FATZ binding(GO:0051373)
0.3	4.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.3	1.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	4.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.3	1.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	14.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3	0.8	GO:0070573	metallodipeptidase activity(GO:0070573)
0.3	1.3	GO:0071813	lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.3	0.8	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.3	0.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.2	1.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.2	1.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2	1.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.2	1.0	GO:0005499	vitamin D binding(GO:0005499)
0.2	1.7	GO:0008494	translation activator activity(GO:0008494)
0.2	1.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.2	0.7	GO:2001069	glycogen binding(GO:2001069)
0.2	0.7	GO:0004096	catalase activity(GO:0004096)
0.2	5.6	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.2	1.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.2	0.7	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.2	0.5	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2	0.9	GO:0001515	opioid peptide activity(GO:0001515)
0.2	2.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.2	12.6	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2	0.9	GO:0036122	BMP binding(GO:0036122)
0.2	1.6	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	0.4	GO:0030984	kininogen binding(GO:0030984)
0.2	0.9	GO:1904288	BAT3 complex binding(GO:1904288)
0.2	1.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	1.5	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	5.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	2.4	GO:0042805	actinin binding(GO:0042805)
0.2	1.5	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.2	0.6	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2	0.4	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.2	0.6	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2	1.7	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2	0.4	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	0.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.2	3.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2	0.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.2	3.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	0.6	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.2	1.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.2	0.6	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.2	5.1	GO:0005267	potassium channel activity(GO:0005267)
0.2	1.5	GO:0015168	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.2	0.2	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2	0.4	GO:0016415	octanoyltransferase activity(GO:0016415)
0.2	0.9	GO:0017166	vinculin binding(GO:0017166)
0.2	2.3	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2	2.3	GO:0043274	phospholipase binding(GO:0043274)
0.2	1.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	0.7	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2	0.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	0.9	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	8.7	GO:0008013	beta-catenin binding(GO:0008013)
0.2	0.9	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2	0.7	GO:0039706	co-receptor binding(GO:0039706)
0.2	5.4	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2	0.3	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.2	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.2	0.9	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.2	1.0	GO:0004383	guanylate cyclase activity(GO:0004383)
0.2	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.2	0.7	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.2	1.2	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2	3.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	1.0	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	8.9	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2	3.8	GO:0043236	laminin binding(GO:0043236)
0.2	6.4	GO:0005080	protein kinase C binding(GO:0005080)
0.2	4.3	GO:0005518	collagen binding(GO:0005518)
0.2	1.0	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.2	0.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	1.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	13.3	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.2	1.9	GO:0070412	R-SMAD binding(GO:0070412)
0.2	10.0	GO:0005178	integrin binding(GO:0005178)
0.2	0.8	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.2	0.5	GO:0030172	troponin C binding(GO:0030172)
0.2	1.5	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.2	11.8	GO:0008083	growth factor activity(GO:0008083)
0.2	0.6	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	1.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	1.0	GO:0051400	BH domain binding(GO:0051400)
0.1	0.7	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.3	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	1.5	GO:0005521	lamin binding(GO:0005521)
0.1	0.4	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	0.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	4.5	GO:0019107	myristoyltransferase activity(GO:0019107)
0.1	0.7	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	3.9	GO:0015485	cholesterol binding(GO:0015485)
0.1	4.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.6	GO:0031432	titin binding(GO:0031432)
0.1	2.4	GO:0044654	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1	1.7	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.3	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.4	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	9.9	GO:0008201	heparin binding(GO:0008201)
0.1	0.3	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	5.7	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.1	1.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	10.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1	0.5	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	30.4	GO:0003779	actin binding(GO:0003779)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.4	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.1	1.0	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.1	0.7	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.6	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.3	GO:0002046	opsin binding(GO:0002046)
0.1	0.3	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1	0.1	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.1	0.3	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.9	GO:0018855	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1	0.3	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0015265	urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265)
0.1	3.6	GO:0019955	cytokine binding(GO:0019955)
0.1	2.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.4	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.6	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.3	GO:0099528	G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1	0.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.1	1.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.4	GO:0015288	porin activity(GO:0015288)
0.1	3.4	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.1	0.3	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1	0.3	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	2.2	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	0.7	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	0.9	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	0.2	GO:0051870	methotrexate binding(GO:0051870)
0.1	0.3	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.9	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.1	0.4	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	1.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.3	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.3	GO:0004370	glycerol kinase activity(GO:0004370)
0.1	0.2	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	1.1	GO:0005231	excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.1	0.9	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	23.8	GO:0005509	calcium ion binding(GO:0005509)
0.1	0.6	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.1	0.1	GO:0015927	trehalase activity(GO:0015927)
0.1	1.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	0.1	GO:0016749	N-succinyltransferase activity(GO:0016749)
0.1	12.6	GO:0005096	GTPase activator activity(GO:0005096)
0.1	0.1	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.1	0.4	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.1	GO:0004027	alcohol sulfotransferase activity(GO:0004027)
0.1	1.0	GO:0030332	cyclin binding(GO:0030332)
0.1	0.1	GO:1901611	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1	0.1	GO:0000009	alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.2	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.2	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1	0.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	0.2	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.1	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	1.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	2.6	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.4	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.4	GO:0030552	cAMP binding(GO:0030552)
0.0	1.2	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.5	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.2	GO:0034584	piRNA binding(GO:0034584)
0.0	0.3	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0003884	D-amino-acid oxidase activity(GO:0003884)
0.0	15.4	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.2	GO:0015172	acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	2.9	GO:0005179	hormone activity(GO:0005179)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	1.2	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.4	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	1.0	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.1	GO:0035276	alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.0	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	1.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.3	GO:0052767	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.0	GO:0008158	hedgehog receptor activity(GO:0008158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	9.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.8	1.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.8	11.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.8	5.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.6	3.6	PID ALK1 PATHWAY	ALK1 signaling events
0.6	22.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.6	17.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.6	8.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.6	17.3	NABA COLLAGENS	Genes encoding collagen proteins
0.6	12.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5	4.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	2.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.5	16.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.5	2.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.5	33.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.4	5.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.4	4.7	PID ALK2 PATHWAY	ALK2 signaling events
0.4	3.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	7.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.4	6.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	5.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	2.8	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	1.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	7.3	PID RAS PATHWAY	Regulation of Ras family activation
0.3	4.9	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	1.5	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	2.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	38.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	12.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	6.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	2.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	1.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	6.1	PID ENDOTHELIN PATHWAY	Endothelins
0.3	1.8	ST G ALPHA I PATHWAY	G alpha i Pathway
0.3	35.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	50.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	2.9	PID EPHB FWD PATHWAY	EPHB forward signaling
0.2	7.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	1.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	8.6	PID FGF PATHWAY	FGF signaling pathway
0.2	5.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	1.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	2.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	1.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	6.2	PID BMP PATHWAY	BMP receptor signaling
0.2	3.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.2	2.5	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	5.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	3.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	4.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	1.9	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	1.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	2.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	0.7	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	32.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	4.0	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	2.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	2.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	1.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.4	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	0.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	0.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	11.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
1.0	10.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
1.0	1.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.9	10.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.8	15.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.8	0.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.8	20.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.7	7.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7	30.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.7	7.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7	5.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.6	3.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.6	13.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.6	7.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.6	7.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6	7.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	6.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.5	13.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.5	18.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.5	5.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.5	6.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.4	4.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	4.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	6.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.4	2.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.4	9.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4	14.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.4	6.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.4	5.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4	9.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.4	14.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.4	1.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4	4.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.4	7.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	5.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	1.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.3	2.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.3	7.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.3	3.5	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3	3.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.3	4.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.3	0.3	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.3	4.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	1.2	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.3	2.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	20.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	4.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	10.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	3.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.3	1.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.3	3.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	21.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.2	2.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	0.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.2	2.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	4.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.2	3.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.2	1.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.8	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.2	1.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2	4.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.2	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	1.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	3.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.2	2.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	0.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.2	1.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	4.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	3.3	REACTOME KINESINS	Genes involved in Kinesins
0.2	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	0.9	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	1.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	5.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	1.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	0.1	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	10.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	1.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	2.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	1.7	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.1	7.6	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	0.1	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.1	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.5	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	0.4	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.1	0.1	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.1	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	3.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	0.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.1	REACTOME DNA REPLICATION	Genes involved in DNA Replication
0.1	0.2	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	3.5	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.0	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters

Results for Hic1

Z-value: 2.24

Motif logo

Transcription factors associated with Hic1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hic1 motif across conditions

Conditions sorted by the z-value of the Hic1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: