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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Hic2

Z-value: 13.22

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Transcription factors associated with Hic2

Gene Symbol	Gene ID	Gene Info
Hic2 Ensembl NCBI MGI UniProt	ENSMUSG00000050240.8	hypermethylated in cancer 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_17233695_17234415	Hic2	391	0.475311	0.58	4.1e-06	Click!
chr16_17225709_17225888	Hic2	7774	0.094039	-0.52	4.9e-05	Click!
chr16_17243810_17244027	Hic2	10254	0.096532	-0.50	1.2e-04	Click!
chr16_17249267_17249459	Hic2	15699	0.091737	-0.38	4.3e-03	Click!
chr16_17252281_17252454	Hic2	18703	0.089044	-0.31	2.0e-02	Click!

Activity of the Hic2 motif across conditions

Conditions sorted by the z-value of the Hic2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_3236518_3237725	122.80	Rab10os	RAB10, member RAS oncogene family, opposite strand	510	0.74
chr9_124439906_124440949	58.06	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	441	0.79
chr14_14350947_14351733	58.01	Il3ra	interleukin 3 receptor, alpha chain	1719	0.23
chr2_153425549_153426538	41.42	Gm14472	predicted gene 14472	12194	0.16
chr10_81559146_81561402	37.10	Tle5	TLE family member 5, transcriptional modulator	770	0.38
chr19_61225302_61226760	35.16	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	541	0.67
chr14_14349938_14350878	34.05	Il3ra	interleukin 3 receptor, alpha chain	787	0.48
chr5_133453797_133453985	33.25	Gm42625	predicted gene 42625	10549	0.22
chr1_20819843_20820501	32.96	Mcm3	minichromosome maintenance complex component 3	88	0.93
chr10_17983401_17983568	30.18	Gm17711	predicted gene, 17711	27784	0.15
chr4_82494936_82495219	29.90	Nfib	nuclear factor I/B	4239	0.24
chr10_62194485_62194811	29.79	Mir7662	microRNA 7662	421	0.47
chr14_55052682_55052968	29.32	Zfhx2os	zinc finger homeobox 2, opposite strand	1044	0.27
chr13_73704941_73705129	28.99	Slc6a19	solute carrier family 6 (neurotransmitter transporter), member 19	170	0.91
chr3_88232209_88232744	28.95	Gm3764	predicted gene 3764	3693	0.1
chr3_88214175_88214875	28.92	Gm3764	predicted gene 3764	30	0.87
chr3_85300020_85300198	28.78	1700036G14Rik	RIKEN cDNA 1700036G14 gene	17410	0.24
chr1_34666183_34666826	28.41	Arhgef4	Rho guanine nucleotide exchange factor (GEF) 4	11684	0.13
chr14_24617341_24617911	28.29	4930428N03Rik	RIKEN cDNA 4930428N03 gene	58	0.64
chr2_33130296_33131698	28.26	Garnl3	GTPase activating RANGAP domain-like 3	389	0.84
chr12_112721309_112722969	28.25	Cep170b	centrosomal protein 170B	35	0.95
chr8_111614648_111614989	27.93	Znrf1	zinc and ring finger 1	5522	0.17
chr1_133181035_133181537	27.00	Plekha6	pleckstrin homology domain containing, family A member 6	35	0.98
chr12_30372910_30373696	26.72	Sntg2	syntrophin, gamma 2	8	0.98
chr12_56415275_56415462	26.32	Gm18027	predicted gene, 18027	4811	0.2
chr18_42740241_42740444	25.93	C030004G16Rik	RIKEN cDNA C030004G16 gene	117883	0.05
chr4_148867978_148868414	25.79	Casz1	castor zinc finger 1	21185	0.18
chr15_85652871_85653067	25.08	Lncppara	long noncoding RNA near Ppara	647	0.66
chr4_39344371_39344735	24.52	Gm23607	predicted gene, 23607	49090	0.15
chr14_123626303_123627238	24.45	Nalcn	sodium leak channel, non-selective	106	0.98
chr11_31767896_31768473	24.44	D630024D03Rik	RIKEN cDNA D630024D03 gene	56289	0.11
chr9_16484808_16485485	23.90	Fat3	FAT atypical cadherin 3	16139	0.27
chr1_155209984_155210436	23.67	BC034090	cDNA sequence BC034090	3771	0.18
chr1_167608265_167608743	23.60	Rxrg	retinoid X receptor gamma	9805	0.27
chr7_4123736_4124170	23.38	Ttyh1	tweety family member 1	536	0.57
chr16_38955368_38955688	23.31	Gm22500	predicted gene, 22500	28319	0.18
chr4_100913798_100913949	23.19	Cachd1	cache domain containing 1	80738	0.09
chr6_91284995_91285433	23.13	Fbln2	fibulin 2	19335	0.17
chr7_49922872_49923348	22.86	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	11410	0.25
chr18_35019023_35019721	22.76	Gm36037	predicted gene, 36037	36402	0.11
chr13_83985066_83985623	22.55	Gm4241	predicted gene 4241	2647	0.28
chr14_19042458_19042951	22.44	Gm48781	predicted gene, 48781	480	0.71
chr8_72646405_72646797	22.38	Nwd1	NACHT and WD repeat domain containing 1	110	0.96
chr7_31127074_31128340	22.38	Scn1b	sodium channel, voltage-gated, type I, beta	704	0.47
chr6_55676658_55677265	22.33	Neurod6	neurogenic differentiation 6	4302	0.26
chr11_24129398_24130415	22.29	Bcl11a	B cell CLL/lymphoma 11A (zinc finger protein)	12473	0.15
chr7_46509699_46510289	22.23	Gm45311	predicted gene 45311	2786	0.23
chr3_80800657_80801686	22.23	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	1408	0.52
chr16_84042025_84042426	22.21	Gm41481	predicted gene, 41481	15159	0.29
chr5_38158989_38159808	22.19	Nsg1	neuron specific gene family member 1	7	0.97
chr2_66634450_66635011	22.06	Scn9a	sodium channel, voltage-gated, type IX, alpha	77	0.98
chr16_35613873_35614640	22.05	Gm5963	predicted pseudogene 5963	40700	0.13
chr1_34583668_34584368	21.98	1700101I19Rik	RIKEN cDNA 1700101I19 gene	4307	0.1
chr3_146397357_146397698	21.79	Gm22901	predicted gene, 22901	1690	0.26
chr10_74922677_74923156	21.57	Gnaz	guanine nucleotide binding protein, alpha z subunit	44261	0.14
chr15_4375774_4376213	21.53	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3	489	0.88
chr8_94567491_94567722	21.40	Cpne2	copine II	4956	0.14
chr14_55054973_55055741	21.29	Gm20687	predicted gene 20687	136	0.88
chr10_26695225_26695646	21.13	Gm48893	predicted gene, 48893	139	0.96
chr1_91209751_91210137	21.09	Ramp1	receptor (calcitonin) activity modifying protein 1	29898	0.11
chr7_44310178_44311500	20.86	Shank1	SH3 and multiple ankyrin repeat domains 1	586	0.43
chr2_154223254_154223780	20.80	Bpifb5	BPI fold containing family B, member 5	225	0.91
chr11_6606254_6606619	20.67	Nacad	NAC alpha domain containing	383	0.7
chr10_59092115_59092323	20.65	Sh3rf3	SH3 domain containing ring finger 3	12185	0.23
chr11_115496116_115496547	20.63	Gm11694	predicted gene 11694	3307	0.1
chr5_84848501_84849167	20.59	Gm21006	predicted gene, 21006	18011	0.3
chr16_91962945_91963627	20.49	Gm27773	predicted gene, 27773	19138	0.1
chr4_91371091_91372260	20.30	Elavl2	ELAV like RNA binding protein 1	281	0.88
chr1_173365799_173366481	20.30	Cadm3	cell adhesion molecule 3	1493	0.35
chr12_3930272_3930423	20.22	Gm9088	predicted gene 9088	1693	0.3
chr4_154948181_154948553	20.20	Hes5	hes family bHLH transcription factor 5	12556	0.11
chr11_3132475_3133419	20.15	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	3060	0.17
chr13_99443818_99444236	20.07	Map1b	microtubule-associated protein 1B	83	0.97
chr14_55054195_55054444	20.07	Zfhx2os	zinc finger homeobox 2, opposite strand	372	0.55
chr1_38450635_38451180	19.94	Gm34727	predicted gene, 34727	36612	0.18
chr9_101404472_101405037	19.88	Gm24638	predicted gene, 24638	11644	0.17
chr8_122751278_122751680	19.84	C230057M02Rik	RIKEN cDNA C230057M02 gene	846	0.44
chr3_108401377_108402718	19.70	Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2	542	0.59
chr11_6599159_6600158	19.63	Nacad	NAC alpha domain containing	266	0.81
chr7_43489442_43490064	19.40	Iglon5	IgLON family member 5	322	0.72
chr2_178142310_178142985	19.39	Phactr3	phosphatase and actin regulator 3	714	0.75
chr4_81727093_81727463	19.39	Gm11412	predicted gene 11412	15868	0.23
chr5_71095688_71096242	19.27	Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	116	0.98
chr3_55242068_55243398	19.25	Dclk1	doublecortin-like kinase 1	207	0.94
chr3_8510380_8510590	19.20	Stmn2	stathmin-like 2	899	0.63
chr14_55053693_55054126	19.14	Zfhx2os	zinc finger homeobox 2, opposite strand	38	0.92
chr6_127079842_127080169	19.06	Fgf23	fibroblast growth factor 23	7103	0.13
chr19_6976181_6976733	18.91	Ppp1r14b	protein phosphatase 1, regulatory inhibitor subunit 14B	8	0.48
chr2_127521161_127522051	18.89	Kcnip3	Kv channel interacting protein 3, calsenilin	236	0.88
chr6_113856666_113857208	18.87	Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	34433	0.12
chr4_40948174_40948980	18.76	Chmp5	charged multivesicular body protein 5	170	0.63
chr2_168106742_168107351	18.75	AL831766.1	breast carcinoma amplified sequence 4 (BCAS4) pseudogene	7831	0.14
chrX_143902692_143902843	18.75	Dcx	doublecortin	30283	0.2
chr17_55985980_55986972	18.50	Fsd1	fibronectin type 3 and SPRY domain-containing protein	33	0.94
chrX_143518921_143519348	18.46	Pak3	p21 (RAC1) activated kinase 3	436	0.9
chr1_120115905_120116482	18.41	Dbi	diazepam binding inhibitor	3945	0.21
chr7_27164811_27165702	18.40	Egln2	egl-9 family hypoxia-inducible factor 2	1026	0.26
chr11_88588635_88589214	18.35	Msi2	musashi RNA-binding protein 2	1223	0.57
chr13_15759168_15760299	18.22	Gm48408	predicted gene, 48408	10387	0.18
chr4_81727500_81727721	18.22	Gm11412	predicted gene 11412	15536	0.24
chr19_10188295_10188461	18.20	Mir6993	microRNA 6993	2997	0.13
chr16_25016242_25016817	18.18	A230028O05Rik	RIKEN cDNA A230028O05 gene	43110	0.19
chr9_45433800_45433951	18.18	4833428L15Rik	RIKEN cDNA 4833428L15 gene	2145	0.22
chr6_91839426_91839831	18.11	Grip2	glutamate receptor interacting protein 2	12378	0.15
chr12_33035669_33036432	18.00	Cdhr3	cadherin-related family member 3	16936	0.14
chr5_111935456_111935676	17.92	Gm42488	predicted gene 42488	8669	0.27
chr9_94611004_94611174	17.90	Gm39404	predicted gene, 39404	18893	0.17
chr3_88225100_88225251	17.85	Gm3764	predicted gene 3764	758	0.4
chr13_84061812_84061979	17.83	Gm17750	predicted gene, 17750	2877	0.3
chr1_167022852_167023009	17.81	Fam78b	family with sequence similarity 78, member B	21341	0.18
chrX_43429975_43430537	17.78	Tenm1	teneurin transmembrane protein 1	1130	0.54
chr3_88207026_88207397	17.75	Gm3764	predicted gene 3764	101	0.91
chr2_62807459_62807865	17.72	Gm13569	predicted gene 13569	1525	0.44
chr9_26733143_26733768	17.69	B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	273	0.88
chr2_26594675_26595827	17.69	Egfl7	EGF-like domain 7	3104	0.11
chr13_83749857_83750036	17.68	C130071C03Rik	RIKEN cDNA C130071C03 gene	11083	0.12
chr7_79499656_79500079	17.68	Mir9-3hg	Mir9-3 host gene	159	0.9
chr5_68149972_68150304	17.68	Gm43025	predicted gene 43025	65764	0.11
chr7_57508956_57510254	17.61	Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	234	0.95
chr12_29871996_29872873	17.58	Myt1l	myelin transcription factor 1-like	20886	0.24
chr10_19318275_19318532	17.54	Gm33056	predicted gene, 33056	27414	0.17
chr10_121309994_121311399	17.52	Tbc1d30	TBC1 domain family, member 30	493	0.76
chr16_8540589_8540924	17.45	Abat	4-aminobutyrate aminotransferase	27271	0.14
chr4_141053276_141054195	17.44	Crocc	ciliary rootlet coiled-coil, rootletin	13	0.96
chr19_41693820_41694136	17.41	Slit1	slit guidance ligand 1	49508	0.13
chr4_22301616_22301795	17.32	Gm11882	predicted gene 11882	25872	0.19
chr17_67071357_67071526	17.32	Ptprm	protein tyrosine phosphatase, receptor type, M	23456	0.2
chr12_29884527_29884691	17.31	Myt1l	myelin transcription factor 1-like	10505	0.26
chr3_55448016_55448187	17.29	Dclk1	doublecortin-like kinase 1	2872	0.22
chr7_79572141_79572757	17.26	Gm45168	predicted gene 45168	6619	0.1
chr12_51117995_51118377	17.15	Gm7172	predicted gene 7172	16516	0.22
chr9_103504895_103505451	17.12	Tmem108	transmembrane protein 108	11562	0.11
chr8_4679817_4680161	17.09	Gm6410	predicted gene 6410	1527	0.23
chrX_135210164_135210824	17.04	Tceal6	transcription elongation factor A (SII)-like 6	193	0.92
chr9_50064901_50065078	16.96	Gm47543	predicted gene, 47543	110111	0.06
chr2_33355615_33355975	16.88	Gm25998	predicted gene, 25998	7251	0.17
chr10_106469332_106470360	16.84	Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	493	0.82
chr11_112501711_112502406	16.79	BC006965	cDNA sequence BC006965	167340	0.04
chr14_49294201_49294352	16.79	Slc35f4	solute carrier family 35, member F4	4997	0.19
chr11_52447248_52447521	16.72	Gm12209	predicted gene 12209	31719	0.13
chr10_80145825_80146996	16.71	Midn	midnolin	1862	0.15
chr8_12915219_12915955	16.66	Gm15351	predicted gene 15351	32	0.8
chr17_9879654_9879852	16.65	Gm49808	predicted gene, 49808	15334	0.19
chr3_40949219_40949942	16.63	Larp1b	La ribonucleoprotein domain family, member 1B	248	0.88
chr13_92733870_92734066	16.58	Gm5199	predicted gene 5199	14606	0.19
chr7_81454347_81455042	16.43	Cpeb1	cytoplasmic polyadenylation element binding protein 1	19	0.95
chr7_79536149_79536360	16.34	Gm35040	predicted gene, 35040	211	0.87
chr3_144124558_144124728	16.23	Gm34078	predicted gene, 34078	11111	0.23
chr10_81364518_81366962	16.18	4930404N11Rik	RIKEN cDNA 4930404N11 gene	50	0.91
chr13_83720847_83721021	16.18	C130071C03Rik	RIKEN cDNA C130071C03 gene	447	0.75
chrX_71050224_71051202	16.15	Mamld1	mastermind-like domain containing 1	457	0.87
chr3_59005933_59006738	16.14	Med12l	mediator complex subunit 12-like	152	0.52
chr3_8510073_8510309	16.14	Stmn2	stathmin-like 2	605	0.77
chr2_165288310_165288938	16.14	Slc35c2	solute carrier family 35, member C2	755	0.58
chr10_86491659_86492093	16.13	Syn3	synapsin III	21	0.96
chr4_134496569_134497650	16.11	Paqr7	progestin and adipoQ receptor family member VII	68	0.95
chr3_105590400_105590551	16.10	Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	78530	0.07
chr7_144449676_144450010	16.09	Cttn	cortactin	69	0.97
chr1_42687059_42687229	16.09	Pantr1	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1	5949	0.15
chr15_44177298_44177482	16.07	Trhr	thyrotropin releasing hormone receptor	18745	0.25
chr17_9905619_9905814	16.00	Gm34799	predicted gene, 34799	24051	0.17
chr11_118792990_118793180	16.00	Gm11750	predicted gene 11750	1713	0.38
chr6_114182505_114182666	15.99	Gm8132	predicted gene 8132	13062	0.21
chr5_24623512_24623989	15.99	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	614	0.58
chr2_172345010_172346316	15.96	Fam210b	family with sequence similarity 210, member B	98	0.95
chr10_5922231_5922649	15.96	Rgs17	regulator of G-protein signaling 17	40	0.99
chr9_56868158_56868636	15.94	Cspg4	chondroitin sulfate proteoglycan 4	3364	0.16
chr6_82939285_82939948	15.83	Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	71	0.94
chr18_74956688_74957137	15.81	Lipg	lipase, endothelial	4350	0.11
chr15_102733338_102733529	15.81	Calcoco1	calcium binding and coiled coil domain 1	11255	0.14
chr13_34133643_34133908	15.80	Gm36500	predicted gene, 36500	85	0.94
chr14_13651648_13651848	15.79	Sntn	sentan, cilia apical structure protein	19128	0.24
chr12_72236963_72237171	15.78	Rtn1	reticulon 1	343	0.9
chr5_103789859_103790167	15.75	Aff1	AF4/FMR2 family, member 1	5654	0.23
chr2_24428384_24428703	15.75	Pax8	paired box 8	5461	0.15
chr8_108510737_108511320	15.73	Gm39244	predicted gene, 39244	25919	0.23
chr9_98525136_98525555	15.72	Gm37113	predicted gene, 37113	31377	0.11
chr14_27167240_27167560	15.71	Gm7591	predicted gene 7591	42997	0.14
chr8_71374903_71376449	15.71	Nr2f6	nuclear receptor subfamily 2, group F, member 6	114	0.92
chr6_40024235_40024578	15.53	Gm37995	predicted gene, 37995	2488	0.33
chr11_97449609_97450728	15.52	Arhgap23	Rho GTPase activating protein 23	8	0.97
chr13_48966851_48968700	15.47	Fam120a	family with sequence similarity 120, member A	242	0.95
chr4_154960398_154960784	15.47	Hes5	hes family bHLH transcription factor 5	332	0.74
chr14_3208167_3209194	15.42	D830030K20Rik	RIKEN cDNA D830030K20 gene	103	0.95
chr5_33689415_33689612	15.39	Gm42965	predicted gene 42965	6539	0.11
chr12_33341296_33341797	15.39	Atxn7l1	ataxin 7-like 1	3759	0.23
chr6_145934272_145934704	15.39	Sspn	sarcospan	366	0.85
chr7_25676228_25676843	15.38	Tmem91	transmembrane protein 91	1369	0.23
chr1_173367824_173368059	15.36	Cadm3	cell adhesion molecule 3	246	0.91
chr1_89302339_89302583	15.33	Gm5259	predicted gene 5259	45480	0.15
chr16_41729236_41729556	15.32	Lsamp	limbic system-associated membrane protein	195977	0.03
chr1_74855060_74855505	15.27	Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	348	0.78
chr15_86419577_86420037	15.24	A930001M01Rik	RIKEN cDNA A930001M01 gene	55288	0.15
chr13_72265859_72266010	15.24	Gm4052	predicted gene 4052	84287	0.09
chr15_25842982_25843686	15.23	Retreg1	reticulophagy regulator 1	154	0.95
chr1_74284190_74285456	15.22	Aamp	angio-associated migratory protein	85	0.51
chr14_105851365_105851748	15.18	Gm48970	predicted gene, 48970	10945	0.21
chr11_88471971_88472344	15.17	Gm11510	predicted gene 11510	38643	0.16
chr11_66222237_66222458	15.15	Dnah9	dynein, axonemal, heavy chain 9	53796	0.15
chr4_120188706_120189284	15.15	Edn2	endothelin 2	27789	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.1	51.3	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
15.3	46.0	GO:0003358	noradrenergic neuron development(GO:0003358)
14.8	44.5	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
12.3	49.0	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
11.3	33.9	GO:0070634	transepithelial ammonium transport(GO:0070634)
10.2	30.7	GO:0021586	pons maturation(GO:0021586)
10.0	79.7	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
9.2	27.6	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
9.2	27.5	GO:0038128	ERBB2 signaling pathway(GO:0038128)
8.8	35.2	GO:0003219	cardiac right ventricle formation(GO:0003219)
8.8	26.3	GO:0072069	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
8.4	33.7	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
8.3	24.8	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
8.3	33.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
8.1	48.8	GO:0021960	anterior commissure morphogenesis(GO:0021960)
8.0	32.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
8.0	24.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
8.0	23.9	GO:0060178	regulation of exocyst localization(GO:0060178)
7.9	23.7	GO:1990034	calcium ion export from cell(GO:1990034)
7.6	30.6	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
7.5	29.9	GO:0023041	neuronal signal transduction(GO:0023041)
7.4	7.4	GO:0001661	conditioned taste aversion(GO:0001661)
7.4	37.2	GO:0042297	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
7.3	21.8	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
7.2	50.7	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
7.1	28.5	GO:0046959	habituation(GO:0046959)
7.1	7.1	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
7.0	55.6	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
6.9	6.9	GO:0021550	medulla oblongata development(GO:0021550)
6.7	20.0	GO:0032289	central nervous system myelin formation(GO:0032289)
6.6	138.9	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
6.5	26.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
6.5	12.9	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
6.4	64.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
6.4	44.6	GO:0016198	axon choice point recognition(GO:0016198)
6.4	25.4	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
6.2	31.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
6.2	6.2	GO:0060221	retinal rod cell differentiation(GO:0060221)
5.9	29.6	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
5.9	11.8	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
5.8	17.3	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
5.8	23.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
5.6	5.6	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
5.5	27.7	GO:1900452	regulation of long term synaptic depression(GO:1900452)
5.5	76.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
5.5	32.9	GO:0045161	neuronal ion channel clustering(GO:0045161)
5.3	21.3	GO:0090427	activation of meiosis(GO:0090427)
5.3	37.0	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
5.2	10.5	GO:0006808	regulation of nitrogen utilization(GO:0006808)
5.2	15.6	GO:0021698	cerebellar cortex structural organization(GO:0021698)
5.2	10.4	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
5.1	15.4	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
5.1	20.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
5.1	15.3	GO:0055099	response to high density lipoprotein particle(GO:0055099)
5.1	15.2	GO:0072318	clathrin coat disassembly(GO:0072318)
5.0	15.1	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
5.0	15.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
5.0	15.0	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
5.0	9.9	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
4.9	68.9	GO:0051654	establishment of mitochondrion localization(GO:0051654)
4.9	49.2	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
4.9	14.6	GO:1904220	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
4.8	4.8	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
4.8	14.5	GO:0071492	cellular response to UV-A(GO:0071492)
4.8	9.6	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
4.8	14.4	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
4.8	14.3	GO:0002121	inter-male aggressive behavior(GO:0002121)
4.7	32.6	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
4.6	23.0	GO:0060278	regulation of ovulation(GO:0060278)
4.6	13.7	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
4.6	18.2	GO:0002051	osteoblast fate commitment(GO:0002051)
4.5	40.8	GO:0086015	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
4.5	9.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
4.5	22.5	GO:0090273	regulation of somatostatin secretion(GO:0090273)
4.5	17.9	GO:1903977	positive regulation of glial cell migration(GO:1903977)
4.5	35.6	GO:0071625	vocalization behavior(GO:0071625)
4.5	8.9	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
4.4	8.9	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
4.4	4.4	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
4.4	34.9	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
4.3	8.7	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
4.3	17.3	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
4.3	17.2	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
4.3	12.8	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
4.3	51.1	GO:0048268	clathrin coat assembly(GO:0048268)
4.2	21.0	GO:0000160	phosphorelay signal transduction system(GO:0000160)
4.1	29.0	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
4.1	32.9	GO:0001964	startle response(GO:0001964)
4.1	12.3	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
4.0	12.1	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
4.0	28.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
4.0	12.0	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
3.9	19.7	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
3.9	23.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
3.9	3.9	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
3.8	11.4	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
3.8	15.2	GO:0022038	corpus callosum development(GO:0022038)
3.8	11.4	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
3.8	22.7	GO:0005513	detection of calcium ion(GO:0005513)
3.8	7.5	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
3.7	26.1	GO:0060134	prepulse inhibition(GO:0060134)
3.7	11.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
3.7	3.7	GO:0021859	pyramidal neuron differentiation(GO:0021859)
3.7	22.0	GO:0035881	amacrine cell differentiation(GO:0035881)
3.7	7.3	GO:0010996	response to auditory stimulus(GO:0010996)
3.6	29.2	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
3.6	69.2	GO:0035418	protein localization to synapse(GO:0035418)
3.6	3.6	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
3.6	10.8	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
3.6	7.2	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
3.6	28.6	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
3.6	17.9	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
3.6	39.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
3.6	21.4	GO:1904424	regulation of GTP binding(GO:1904424)
3.5	10.6	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
3.5	14.1	GO:0006538	glutamate catabolic process(GO:0006538)
3.5	3.5	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
3.5	10.4	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
3.5	10.4	GO:0001927	exocyst assembly(GO:0001927)
3.4	161.3	GO:0051965	positive regulation of synapse assembly(GO:0051965)
3.4	17.1	GO:0036233	glycine import(GO:0036233)
3.4	10.2	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
3.4	6.8	GO:0072053	renal inner medulla development(GO:0072053)
3.4	10.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
3.4	13.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
3.3	10.0	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
3.3	259.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
3.3	3.3	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
3.3	46.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
3.3	16.5	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
3.3	3.3	GO:0021557	oculomotor nerve development(GO:0021557)
3.3	13.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
3.3	6.5	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
3.3	3.3	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
3.3	9.8	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.2	3.2	GO:0097091	synaptic vesicle clustering(GO:0097091) regulation of synaptic vesicle clustering(GO:2000807)
3.2	9.6	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
3.2	12.8	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
3.2	19.1	GO:0046069	cGMP catabolic process(GO:0046069)
3.2	9.5	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
3.2	12.7	GO:0007258	JUN phosphorylation(GO:0007258)
3.2	9.5	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
3.1	18.8	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
3.1	21.7	GO:0010457	centriole-centriole cohesion(GO:0010457)
3.1	9.3	GO:0021747	cochlear nucleus development(GO:0021747)
3.1	6.1	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
3.0	9.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
3.0	9.1	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
3.0	9.1	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
3.0	18.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
3.0	9.0	GO:0030070	insulin processing(GO:0030070)
3.0	6.0	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
3.0	8.9	GO:0021764	amygdala development(GO:0021764)
3.0	11.9	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
3.0	17.8	GO:0060011	Sertoli cell proliferation(GO:0060011)
3.0	8.9	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
3.0	8.9	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
2.9	14.7	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
2.9	26.4	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
2.9	8.8	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
2.9	8.8	GO:1901529	positive regulation of anion channel activity(GO:1901529)
2.9	35.0	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
2.9	5.8	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.9	20.2	GO:0021542	dentate gyrus development(GO:0021542)
2.9	23.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.9	8.6	GO:0033566	gamma-tubulin complex localization(GO:0033566)
2.8	2.8	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
2.8	8.5	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
2.8	8.5	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
2.8	19.7	GO:0006108	malate metabolic process(GO:0006108)
2.8	2.8	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
2.8	11.2	GO:1900164	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
2.8	19.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
2.8	8.4	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
2.8	13.9	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
2.8	11.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
2.8	68.8	GO:0019228	neuronal action potential(GO:0019228)
2.7	8.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
2.7	19.2	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
2.7	8.2	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
2.7	8.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
2.7	8.2	GO:1901475	pyruvate transmembrane transport(GO:1901475)
2.7	8.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
2.7	2.7	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
2.7	10.7	GO:0045829	negative regulation of isotype switching(GO:0045829)
2.7	2.7	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
2.7	13.4	GO:0071420	cellular response to histamine(GO:0071420)
2.7	10.7	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
2.6	2.6	GO:1903416	response to glycoside(GO:1903416)
2.6	15.7	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
2.6	2.6	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
2.6	36.5	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
2.6	5.2	GO:0021562	vestibulocochlear nerve development(GO:0021562)
2.6	5.2	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
2.6	7.8	GO:0046098	guanine metabolic process(GO:0046098)
2.6	5.2	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
2.6	7.7	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
2.6	5.1	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
2.6	15.4	GO:0021979	hypothalamus cell differentiation(GO:0021979)
2.6	12.8	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
2.6	43.5	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
2.6	2.6	GO:0042420	dopamine catabolic process(GO:0042420)
2.5	7.6	GO:0014029	neural crest formation(GO:0014029)
2.5	22.9	GO:0035641	locomotory exploration behavior(GO:0035641)
2.5	15.1	GO:0090527	actin filament reorganization(GO:0090527)
2.5	2.5	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
2.5	7.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
2.5	12.5	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
2.5	5.0	GO:0045759	negative regulation of action potential(GO:0045759)
2.5	12.4	GO:0033762	response to glucagon(GO:0033762)
2.5	7.4	GO:0006553	lysine metabolic process(GO:0006553)
2.4	7.3	GO:0042360	vitamin E metabolic process(GO:0042360)
2.4	23.7	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
2.4	4.7	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
2.4	9.4	GO:0042428	serotonin metabolic process(GO:0042428)
2.4	37.6	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
2.3	16.4	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
2.3	4.7	GO:0051665	membrane raft localization(GO:0051665)
2.3	14.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
2.3	4.7	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
2.3	9.3	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
2.3	4.6	GO:0033693	neurofilament bundle assembly(GO:0033693)
2.3	4.6	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
2.3	13.7	GO:0050957	equilibrioception(GO:0050957)
2.3	2.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
2.3	6.8	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
2.3	13.5	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
2.2	6.7	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
2.2	8.9	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
2.2	4.5	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
2.2	4.4	GO:0006382	adenosine to inosine editing(GO:0006382)
2.2	6.6	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
2.2	4.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
2.2	2.2	GO:0060460	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
2.2	4.4	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
2.2	13.0	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
2.2	6.5	GO:0097105	presynaptic membrane assembly(GO:0097105)
2.1	6.4	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
2.1	4.3	GO:0051964	negative regulation of synapse assembly(GO:0051964)
2.1	6.4	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
2.1	4.3	GO:0071873	response to norepinephrine(GO:0071873)
2.1	6.4	GO:2001025	positive regulation of response to drug(GO:2001025)
2.1	2.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
2.1	4.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
2.1	2.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
2.1	4.1	GO:0035973	aggrephagy(GO:0035973)
2.0	8.2	GO:0021854	hypothalamus development(GO:0021854)
2.0	12.3	GO:0042118	endothelial cell activation(GO:0042118)
2.0	10.2	GO:0007413	axonal fasciculation(GO:0007413)
2.0	30.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
2.0	8.1	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
2.0	16.2	GO:0032306	regulation of prostaglandin secretion(GO:0032306)
2.0	14.2	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
2.0	4.0	GO:0035262	gonad morphogenesis(GO:0035262)
2.0	4.0	GO:0035930	corticosteroid hormone secretion(GO:0035930) regulation of corticosteroid hormone secretion(GO:2000846)
2.0	6.0	GO:0032025	response to cobalt ion(GO:0032025)
2.0	6.0	GO:0019087	transformation of host cell by virus(GO:0019087)
2.0	15.9	GO:0060579	ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
2.0	4.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
2.0	5.9	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
2.0	2.0	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
1.9	3.9	GO:1990123	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
1.9	9.7	GO:0021871	forebrain regionalization(GO:0021871)
1.9	5.8	GO:0019086	late viral transcription(GO:0019086)
1.9	5.8	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
1.9	5.8	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.9	11.5	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.9	7.6	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
1.9	5.7	GO:0099623	regulation of cardiac muscle cell membrane repolarization(GO:0099623)
1.9	3.8	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.9	1.9	GO:0051584	regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
1.9	3.8	GO:0089700	protein kinase D signaling(GO:0089700)
1.9	3.8	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.9	5.6	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
1.8	5.5	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
1.8	14.7	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.8	12.9	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.8	67.8	GO:0008333	endosome to lysosome transport(GO:0008333)
1.8	7.3	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
1.8	1.8	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
1.8	18.0	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.8	5.4	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
1.8	1.8	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
1.8	3.6	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.8	1.8	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
1.8	10.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.8	3.5	GO:0099612	protein localization to axon(GO:0099612)
1.8	10.5	GO:0016082	synaptic vesicle priming(GO:0016082)
1.7	5.2	GO:0030167	proteoglycan catabolic process(GO:0030167)
1.7	8.7	GO:0033227	dsRNA transport(GO:0033227)
1.7	7.0	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7	5.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
1.7	6.9	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
1.7	5.1	GO:0060437	lung growth(GO:0060437)
1.7	1.7	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.7	3.4	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.7	3.4	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.7	1.7	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
1.7	11.8	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
1.7	5.0	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
1.7	1.7	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
1.7	6.7	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
1.7	5.0	GO:0051684	maintenance of Golgi location(GO:0051684)
1.7	3.3	GO:0009233	menaquinone metabolic process(GO:0009233)
1.6	6.6	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.6	23.0	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.6	9.8	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
1.6	4.9	GO:0018095	protein polyglutamylation(GO:0018095)
1.6	4.9	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.6	8.1	GO:0006642	triglyceride mobilization(GO:0006642)
1.6	4.8	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
1.6	6.4	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
1.6	4.8	GO:0007220	Notch receptor processing(GO:0007220)
1.6	8.0	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
1.6	6.4	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
1.6	4.8	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
1.6	1.6	GO:0001840	neural plate development(GO:0001840)
1.6	4.8	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.6	4.8	GO:0060005	vestibular reflex(GO:0060005)
1.6	15.8	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
1.6	7.9	GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
1.6	4.7	GO:0060300	regulation of cytokine activity(GO:0060300)
1.6	4.7	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
1.6	6.3	GO:0016048	detection of temperature stimulus(GO:0016048)
1.6	4.7	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.6	4.7	GO:0046952	ketone body catabolic process(GO:0046952)
1.5	10.8	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
1.5	167.3	GO:0071805	potassium ion transmembrane transport(GO:0071805)
1.5	3.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.5	4.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.5	6.1	GO:0070314	G1 to G0 transition(GO:0070314)
1.5	1.5	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
1.5	1.5	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
1.5	6.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
1.5	41.0	GO:0034605	cellular response to heat(GO:0034605)
1.5	1.5	GO:0035524	proline transmembrane transport(GO:0035524)
1.5	1.5	GO:1901420	negative regulation of response to alcohol(GO:1901420)
1.5	6.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
1.5	7.6	GO:0007256	activation of JNKK activity(GO:0007256)
1.5	7.5	GO:0051095	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
1.5	12.0	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
1.5	4.5	GO:0015824	proline transport(GO:0015824)
1.5	6.0	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
1.5	1.5	GO:2000848	positive regulation of cortisol secretion(GO:0051464) positive regulation of corticosteroid hormone secretion(GO:2000848) positive regulation of glucocorticoid secretion(GO:2000851)
1.5	4.4	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.5	3.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.5	4.4	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
1.5	4.4	GO:0015888	thiamine transport(GO:0015888)
1.5	4.4	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.5	1.5	GO:0048382	mesendoderm development(GO:0048382)
1.5	1.5	GO:0014042	positive regulation of neuron maturation(GO:0014042)
1.5	2.9	GO:0070253	somatostatin secretion(GO:0070253)
1.5	17.5	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
1.5	4.4	GO:0060468	prevention of polyspermy(GO:0060468)
1.5	1.5	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.4	53.2	GO:0046847	filopodium assembly(GO:0046847)
1.4	5.8	GO:0070986	left/right axis specification(GO:0070986)
1.4	2.9	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
1.4	2.9	GO:0050915	sensory perception of sour taste(GO:0050915)
1.4	11.5	GO:0070050	neuron cellular homeostasis(GO:0070050)
1.4	7.1	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.4	2.8	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
1.4	2.8	GO:0014028	notochord formation(GO:0014028)
1.4	4.3	GO:0007042	lysosomal lumen acidification(GO:0007042)
1.4	2.8	GO:0003344	pericardium morphogenesis(GO:0003344)
1.4	5.7	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.4	8.5	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
1.4	4.2	GO:0006597	spermine biosynthetic process(GO:0006597)
1.4	5.6	GO:0022417	protein maturation by protein folding(GO:0022417)
1.4	5.6	GO:0043615	astrocyte cell migration(GO:0043615)
1.4	7.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
1.4	5.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
1.4	5.5	GO:0071494	cellular response to UV-C(GO:0071494)
1.4	6.9	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.4	6.8	GO:0030259	lipid glycosylation(GO:0030259)
1.4	4.1	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
1.3	4.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
1.3	2.7	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662)
1.3	4.0	GO:0030242	pexophagy(GO:0030242)
1.3	4.0	GO:0009642	response to light intensity(GO:0009642)
1.3	4.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
1.3	10.6	GO:0060973	cell migration involved in heart development(GO:0060973)
1.3	5.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
1.3	3.9	GO:2001206	positive regulation of osteoclast development(GO:2001206)
1.3	3.9	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
1.3	23.5	GO:0006836	neurotransmitter transport(GO:0006836)
1.3	2.6	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
1.3	1.3	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
1.3	2.6	GO:0015755	fructose transport(GO:0015755)
1.3	3.9	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
1.3	2.6	GO:0090135	actin filament branching(GO:0090135)
1.3	2.6	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
1.3	15.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.3	3.9	GO:0035459	cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
1.3	6.4	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) cilium movement involved in cell motility(GO:0060294)
1.3	7.7	GO:0010842	retina layer formation(GO:0010842)
1.3	1.3	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
1.3	6.4	GO:0010459	negative regulation of heart rate(GO:0010459)
1.3	1.3	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
1.3	19.2	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
1.3	3.8	GO:0048149	behavioral response to ethanol(GO:0048149)
1.3	5.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.3	2.5	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
1.3	3.8	GO:0002930	trabecular meshwork development(GO:0002930)
1.3	3.8	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
1.3	3.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.3	8.8	GO:0009435	NAD biosynthetic process(GO:0009435)
1.3	3.8	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
1.3	3.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
1.3	3.8	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
1.3	2.5	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
1.3	5.0	GO:0007614	short-term memory(GO:0007614)
1.2	1.2	GO:0015705	iodide transport(GO:0015705)
1.2	1.2	GO:0071896	protein localization to adherens junction(GO:0071896)
1.2	1.2	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
1.2	13.6	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
1.2	6.2	GO:0021670	lateral ventricle development(GO:0021670)
1.2	12.3	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.2	12.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.2	2.4	GO:0006562	proline catabolic process(GO:0006562)
1.2	1.2	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
1.2	2.4	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
1.2	3.6	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
1.2	1.2	GO:2000437	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
1.2	6.0	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.2	13.3	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.2	1.2	GO:0015819	lysine transport(GO:0015819)
1.2	2.4	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
1.2	2.4	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
1.2	2.4	GO:0072663	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
1.2	9.5	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
1.2	3.6	GO:0015816	glycine transport(GO:0015816)
1.2	19.0	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
1.2	1.2	GO:0010966	regulation of phosphate transport(GO:0010966)
1.2	8.3	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
1.2	33.0	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.2	3.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.2	1.2	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
1.2	4.6	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
1.2	10.4	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
1.2	3.5	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.2	3.5	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.1	2.3	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.1	2.3	GO:0060013	righting reflex(GO:0060013)
1.1	11.4	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
1.1	4.6	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.1	5.7	GO:0001975	response to amphetamine(GO:0001975)
1.1	3.4	GO:0060632	regulation of microtubule-based movement(GO:0060632)
1.1	1.1	GO:0060061	Spemann organizer formation(GO:0060061)
1.1	9.0	GO:0060997	dendritic spine morphogenesis(GO:0060997)
1.1	3.3	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
1.1	5.6	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.1	3.3	GO:0060618	nipple development(GO:0060618)
1.1	4.4	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
1.1	3.3	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
1.1	7.7	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
1.1	4.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
1.1	3.3	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
1.1	1.1	GO:2000574	regulation of microtubule motor activity(GO:2000574)
1.1	4.4	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.1	3.3	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.1	7.7	GO:0036065	fucosylation(GO:0036065)
1.1	1.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
1.1	5.4	GO:0070327	thyroid hormone transport(GO:0070327)
1.1	7.6	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
1.1	9.7	GO:0035428	hexose transmembrane transport(GO:0035428)
1.1	5.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.1	4.3	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
1.1	24.7	GO:0050885	neuromuscular process controlling balance(GO:0050885)
1.1	2.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
1.1	2.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
1.1	3.2	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
1.1	2.1	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
1.1	5.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
1.1	23.5	GO:0007270	neuron-neuron synaptic transmission(GO:0007270)
1.1	4.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
1.1	5.3	GO:0031642	negative regulation of myelination(GO:0031642)
1.1	2.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
1.1	2.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
1.1	3.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.1	3.2	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
1.1	2.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
1.1	3.2	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.1	3.2	GO:0060179	male mating behavior(GO:0060179)
1.0	3.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.0	2.1	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
1.0	2.1	GO:0006041	glucosamine metabolic process(GO:0006041)
1.0	12.4	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
1.0	9.3	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
1.0	4.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
1.0	1.0	GO:0009996	negative regulation of cell fate specification(GO:0009996)
1.0	2.1	GO:0060166	olfactory pit development(GO:0060166)
1.0	1.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
1.0	4.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
1.0	2.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
1.0	1.0	GO:0070294	renal sodium ion absorption(GO:0070294)
1.0	1.0	GO:0098901	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) regulation of cardiac muscle cell action potential(GO:0098901)
1.0	60.5	GO:0001578	microtubule bundle formation(GO:0001578)
1.0	37.2	GO:0099643	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
1.0	1.0	GO:0072017	distal tubule development(GO:0072017)
1.0	8.0	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.0	1.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
1.0	3.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
1.0	20.9	GO:0031110	regulation of microtubule polymerization or depolymerization(GO:0031110)
1.0	4.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
1.0	2.0	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.0	2.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
1.0	23.7	GO:0006270	DNA replication initiation(GO:0006270)
1.0	3.9	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.0	3.9	GO:1903779	regulation of cardiac conduction(GO:1903779)
1.0	1.0	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
1.0	3.9	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.0	3.9	GO:0021511	spinal cord patterning(GO:0021511)
1.0	3.9	GO:0019478	D-amino acid catabolic process(GO:0019478)
1.0	3.9	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
1.0	1.9	GO:0042940	D-amino acid transport(GO:0042940)
1.0	1.0	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
1.0	5.8	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
1.0	2.9	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
1.0	1.9	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
1.0	10.5	GO:0036342	post-anal tail morphogenesis(GO:0036342)
1.0	1.9	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.9	2.8	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.9	2.8	GO:0006522	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
0.9	1.9	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.9	2.8	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.9	6.6	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.9	1.9	GO:0021516	dorsal spinal cord development(GO:0021516)
0.9	7.5	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.9	0.9	GO:0030497	fatty acid elongation(GO:0030497)
0.9	6.5	GO:2001258	negative regulation of cation channel activity(GO:2001258)
0.9	4.6	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	2.8	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.9	1.8	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.9	3.7	GO:0032482	Rab protein signal transduction(GO:0032482)
0.9	1.8	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.9	1.8	GO:0032252	secretory granule localization(GO:0032252)
0.9	10.9	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9	1.8	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.9	5.4	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.9	7.2	GO:0060180	female mating behavior(GO:0060180)
0.9	13.5	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.9	2.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.9	3.5	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.9	2.7	GO:0002371	dendritic cell cytokine production(GO:0002371) regulation of dendritic cell cytokine production(GO:0002730)
0.9	1.8	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.9	2.6	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.9	4.4	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.9	0.9	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.9	2.6	GO:1901642	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.9	1.7	GO:0002692	negative regulation of cellular extravasation(GO:0002692)
0.9	3.5	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.9	2.6	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.9	8.6	GO:0016486	peptide hormone processing(GO:0016486)
0.9	4.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.9	1.7	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.8	0.8	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.8	5.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.8	3.4	GO:1903301	positive regulation of hexokinase activity(GO:1903301)
0.8	3.4	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.8	2.5	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.8	2.5	GO:0006177	GMP biosynthetic process(GO:0006177)
0.8	0.8	GO:0070368	regulation of hepatocyte differentiation(GO:0070366) positive regulation of hepatocyte differentiation(GO:0070368)
0.8	13.3	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.8	4.2	GO:0031000	response to caffeine(GO:0031000)
0.8	1.7	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.8	8.2	GO:0021766	hippocampus development(GO:0021766)
0.8	2.4	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.8	0.8	GO:0002339	B cell selection(GO:0002339)
0.8	15.4	GO:0007340	acrosome reaction(GO:0007340)
0.8	3.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.8	4.8	GO:0018344	protein geranylgeranylation(GO:0018344)
0.8	1.6	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.8	5.6	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.8	8.0	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.8	2.4	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.8	9.4	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.8	1.6	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.8	3.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.8	1.6	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.8	7.7	GO:0061462	protein localization to lysosome(GO:0061462)
0.8	2.3	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.8	0.8	GO:0090365	regulation of mRNA modification(GO:0090365)
0.8	1.5	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.8	1.5	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.8	3.1	GO:0046548	retinal rod cell development(GO:0046548)
0.8	0.8	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.8	42.7	GO:0007626	locomotory behavior(GO:0007626)
0.8	5.3	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.8	0.8	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.8	23.3	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.7	3.0	GO:0015858	nucleoside transport(GO:0015858)
0.7	1.5	GO:0061511	centriole elongation(GO:0061511)
0.7	1.5	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.7	3.7	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.7	0.7	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.7	1.5	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.7	0.7	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.7	1.5	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.7	3.6	GO:0060736	prostate gland growth(GO:0060736)
0.7	5.1	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.7	0.7	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7	1.4	GO:0035092	sperm chromatin condensation(GO:0035092)
0.7	5.0	GO:0019226	transmission of nerve impulse(GO:0019226)
0.7	6.4	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.7	0.7	GO:0072205	metanephric collecting duct development(GO:0072205)
0.7	5.7	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.7	1.4	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.7	2.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.7	2.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.7	2.1	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.7	1.4	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.7	1.4	GO:0072679	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.7	2.8	GO:0000012	single strand break repair(GO:0000012)
0.7	2.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.7	2.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.7	2.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.7	4.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.7	2.8	GO:0030091	protein repair(GO:0030091)
0.7	2.8	GO:0070995	NADPH oxidation(GO:0070995)
0.7	1.4	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.7	0.7	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.7	0.7	GO:0051350	negative regulation of lyase activity(GO:0051350)
0.7	4.1	GO:0015074	DNA integration(GO:0015074)
0.7	4.8	GO:1903405	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.7	2.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.7	14.9	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.7	4.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.7	1.3	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.7	2.7	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.7	14.8	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.7	2.7	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.7	0.7	GO:0000189	MAPK import into nucleus(GO:0000189)
0.7	4.0	GO:0015800	acidic amino acid transport(GO:0015800)
0.7	1.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.7	6.6	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.6	5.2	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.6	1.3	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6	3.8	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.6	2.6	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.6	1.3	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.6	2.5	GO:0001696	gastric acid secretion(GO:0001696)
0.6	4.4	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.6	2.5	GO:0015884	folic acid transport(GO:0015884)
0.6	0.6	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.6	3.7	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.6	3.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.6	1.2	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.6	1.2	GO:0010046	response to mycotoxin(GO:0010046)
0.6	1.2	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.6	1.8	GO:0072093	ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.6	1.8	GO:0042048	olfactory behavior(GO:0042048)
0.6	1.2	GO:0009629	response to gravity(GO:0009629)
0.6	1.8	GO:0035425	autocrine signaling(GO:0035425)
0.6	1.7	GO:0001895	retina homeostasis(GO:0001895)
0.6	1.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.6	0.6	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.6	0.6	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
0.6	1.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.6	1.1	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.6	1.1	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.6	6.1	GO:0008210	estrogen metabolic process(GO:0008210)
0.6	1.7	GO:0045054	constitutive secretory pathway(GO:0045054)
0.6	2.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.6	0.6	GO:0030035	microspike assembly(GO:0030035)
0.5	3.8	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.5	2.7	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5	0.5	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.5	0.5	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.5	1.6	GO:0030157	pancreatic juice secretion(GO:0030157)
0.5	5.3	GO:0036297	interstrand cross-link repair(GO:0036297)
0.5	3.2	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.5	3.7	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.5	0.5	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.5	0.5	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) positive regulation of transcription by glucose(GO:0046016)
0.5	2.6	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.5	1.6	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.5	1.6	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.5	0.5	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.5	0.5	GO:0035637	multicellular organismal signaling(GO:0035637)
0.5	0.5	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.5	1.0	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.5	5.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.5	1.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.5	2.5	GO:0006528	asparagine metabolic process(GO:0006528)
0.5	4.5	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.5	0.5	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.5	1.5	GO:0060074	synapse maturation(GO:0060074)
0.5	3.0	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.5	1.9	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5	0.5	GO:0043313	regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.5	1.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.5	0.5	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.5	1.9	GO:0080009	mRNA methylation(GO:0080009)
0.5	1.4	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.5	3.3	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.5	1.4	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.5	3.7	GO:0006020	inositol metabolic process(GO:0006020)
0.5	0.9	GO:0071600	otic vesicle morphogenesis(GO:0071600)
0.5	1.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5	0.5	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.5	2.3	GO:1901678	iron coordination entity transport(GO:1901678)
0.5	0.5	GO:1900221	regulation of beta-amyloid clearance(GO:1900221)
0.5	2.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.5	3.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.5	8.6	GO:0006813	potassium ion transport(GO:0006813)
0.5	1.4	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.4	9.4	GO:0048278	vesicle docking(GO:0048278)
0.4	1.3	GO:0042069	regulation of catecholamine metabolic process(GO:0042069)
0.4	0.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.4	2.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.4	1.3	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.4	4.3	GO:0030224	monocyte differentiation(GO:0030224)
0.4	0.9	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.4	2.2	GO:0051451	myoblast migration(GO:0051451)
0.4	1.3	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.4	1.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.4	6.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.4	4.2	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.4	1.3	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.4	2.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.4	1.3	GO:0007638	mechanosensory behavior(GO:0007638)
0.4	1.7	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4	0.8	GO:0042417	dopamine metabolic process(GO:0042417)
0.4	1.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4	1.2	GO:0003157	endocardium development(GO:0003157)
0.4	0.8	GO:0040034	regulation of development, heterochronic(GO:0040034)
0.4	1.2	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.4	0.4	GO:0086026	atrial cardiac muscle cell action potential(GO:0086014) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
0.4	3.2	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.4	1.6	GO:0035627	ceramide transport(GO:0035627)
0.4	1.6	GO:0051697	protein delipidation(GO:0051697)
0.4	2.4	GO:0034453	microtubule anchoring(GO:0034453)
0.4	3.6	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.4	1.2	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4	2.7	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4	2.0	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4	0.8	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4	0.4	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.4	0.4	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.4	0.4	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
0.4	0.4	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.4	0.8	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4	0.7	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.4	0.4	GO:0044783	G1 DNA damage checkpoint(GO:0044783)
0.4	1.5	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.4	0.4	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.4	0.7	GO:0060406	positive regulation of penile erection(GO:0060406)
0.4	0.4	GO:0071865	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.4	1.8	GO:0090161	Golgi ribbon formation(GO:0090161)
0.4	0.4	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.4	1.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.3	1.0	GO:0031296	B cell costimulation(GO:0031296)
0.3	1.4	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.3	1.4	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.3	0.3	GO:0005984	disaccharide metabolic process(GO:0005984)
0.3	3.0	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.3	3.4	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.3	1.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.3	1.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3	5.7	GO:0042246	tissue regeneration(GO:0042246)
0.3	0.3	GO:0048859	formation of anatomical boundary(GO:0048859)
0.3	2.3	GO:0050805	negative regulation of synaptic transmission(GO:0050805)
0.3	2.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3	1.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.3	0.3	GO:0061055	myotome development(GO:0061055)
0.3	2.6	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.3	1.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3	0.3	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3	2.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.3	0.6	GO:0070203	regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.3	1.6	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.3	0.6	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.3	1.2	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.3	0.6	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.3	0.3	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.3	4.8	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.3	0.9	GO:0015846	polyamine transport(GO:0015846)
0.3	0.3	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.3	2.1	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.3	2.6	GO:0045056	transcytosis(GO:0045056)
0.3	0.6	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.3	0.6	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.3	1.1	GO:0035902	response to immobilization stress(GO:0035902)
0.3	4.8	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3	1.4	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3	0.6	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3	1.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3	4.1	GO:1902017	regulation of cilium assembly(GO:1902017)
0.3	0.5	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.3	0.8	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3	1.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.3	2.4	GO:0000103	sulfate assimilation(GO:0000103)
0.3	2.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.3	0.3	GO:0017085	response to insecticide(GO:0017085)
0.3	0.8	GO:0048014	Tie signaling pathway(GO:0048014)
0.3	0.3	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.3	0.8	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.3	0.5	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.3	0.8	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3	0.3	GO:0007567	parturition(GO:0007567)
0.3	0.5	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.3	3.5	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.2	1.0	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2	0.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.2	0.7	GO:0009106	lipoate metabolic process(GO:0009106)
0.2	0.7	GO:0042126	nitrate metabolic process(GO:0042126)
0.2	1.0	GO:0036315	cellular response to sterol(GO:0036315)
0.2	0.2	GO:1902990	telomere maintenance via semi-conservative replication(GO:0032201) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2	0.7	GO:0006450	regulation of translational fidelity(GO:0006450)
0.2	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	1.9	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.2	0.2	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.2	0.9	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2	0.7	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.2	0.7	GO:0006551	leucine metabolic process(GO:0006551)
0.2	0.4	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.2	11.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	0.4	GO:1904504	lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2	5.3	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.2	0.4	GO:0001757	somite specification(GO:0001757)
0.2	1.7	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.2	0.4	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.2	0.2	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2	0.2	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.2	0.4	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.2	1.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.2	1.5	GO:0072525	pyridine-containing compound biosynthetic process(GO:0072525)
0.2	0.2	GO:0021681	cerebellar granular layer development(GO:0021681)
0.2	1.3	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2	0.2	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.2	3.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.2	0.7	GO:0071047	nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2	0.4	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.2	0.7	GO:0001955	blood vessel maturation(GO:0001955)
0.2	0.4	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.2	0.2	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.2	0.2	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.2	0.9	GO:0002934	desmosome organization(GO:0002934)
0.2	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	2.5	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.2	0.5	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2	2.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.2	2.3	GO:0006491	N-glycan processing(GO:0006491)
0.2	1.3	GO:0051646	mitochondrion localization(GO:0051646)
0.2	1.0	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.2	0.6	GO:0098856	intestinal lipid absorption(GO:0098856)
0.2	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2	0.5	GO:0009139	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.4	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.3	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	0.7	GO:0060749	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.1	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1	0.7	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.1	0.3	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.1	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	1.1	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1	0.8	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	0.4	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.8	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.1	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.1	0.4	GO:0042640	anagen(GO:0042640)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.5	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
0.1	0.5	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	2.8	GO:0019835	cytolysis(GO:0019835)
0.1	1.2	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1	0.1	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1	0.2	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	0.1	GO:2001201	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1	0.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.1	0.7	GO:0060346	bone trabecula formation(GO:0060346)
0.1	0.1	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	1.7	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.1	0.8	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.4	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.1	0.3	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.1	0.1	GO:0042891	antibiotic transport(GO:0042891)
0.1	0.1	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1	0.4	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.1	0.6	GO:0006517	protein deglycosylation(GO:0006517)
0.1	2.0	GO:0006400	tRNA modification(GO:0006400)
0.1	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.4	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.1	0.1	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.1	0.4	GO:0010793	regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.1	3.1	GO:1902807	negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.1	0.5	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1	0.8	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	0.1	GO:1904292	regulation of ERAD pathway(GO:1904292)
0.1	0.1	GO:0010446	response to alkaline pH(GO:0010446)
0.1	0.1	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	0.1	GO:0007320	insemination(GO:0007320)
0.1	3.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805) single-organism membrane invagination(GO:1902534)
0.1	0.2	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.3	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.1	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.5	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.2	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1	0.7	GO:0097352	autophagosome maturation(GO:0097352)
0.1	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.1	GO:0019042	viral latency(GO:0019042)
0.1	0.1	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.1	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	1.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.4	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.0	GO:0070202	regulation of establishment of protein localization to chromosome(GO:0070202)
0.0	0.0	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858)
0.0	0.3	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.3	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.0	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.0	0.9	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.1	GO:0006056	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.0	GO:0098739	import across plasma membrane(GO:0098739)
0.0	0.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0007135	meiosis II(GO:0007135)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.0	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.0	GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.7	32.1	GO:0005899	insulin receptor complex(GO:0005899)
9.4	28.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
7.6	76.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
7.5	45.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
7.0	21.0	GO:1990812	growth cone filopodium(GO:1990812)
7.0	48.8	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
6.6	33.0	GO:0097433	dense body(GO:0097433)
6.6	19.7	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
6.4	25.6	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
6.2	18.7	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
6.2	166.5	GO:0048786	presynaptic active zone(GO:0048786)
6.1	36.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
6.0	6.0	GO:0005883	neurofilament(GO:0005883)
6.0	30.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
6.0	71.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
5.9	17.6	GO:0072534	perineuronal net(GO:0072534)
5.7	17.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
5.2	181.9	GO:0042734	presynaptic membrane(GO:0042734)
5.1	10.2	GO:0044326	dendritic spine neck(GO:0044326)
4.9	4.9	GO:0030121	AP-1 adaptor complex(GO:0030121)
4.7	47.4	GO:0030673	axolemma(GO:0030673)
4.7	14.1	GO:0097441	basilar dendrite(GO:0097441)
4.7	18.7	GO:0033010	paranodal junction(GO:0033010)
4.5	72.7	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
4.5	4.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
4.4	8.8	GO:0033268	node of Ranvier(GO:0033268)
4.4	123.0	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
4.3	8.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
4.1	37.3	GO:0035253	ciliary rootlet(GO:0035253)
4.0	48.5	GO:0071564	npBAF complex(GO:0071564)
3.9	46.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
3.9	11.7	GO:0043511	inhibin complex(GO:0043511)
3.9	11.6	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
3.9	27.0	GO:0032584	growth cone membrane(GO:0032584)
3.7	14.9	GO:0043194	axon initial segment(GO:0043194)
3.7	40.3	GO:0042555	MCM complex(GO:0042555)
3.7	11.0	GO:0097427	microtubule bundle(GO:0097427)
3.6	86.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
3.5	87.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
3.3	36.8	GO:0030877	beta-catenin destruction complex(GO:0030877)
3.3	13.3	GO:1990716	axonemal central apparatus(GO:1990716)
3.3	9.9	GO:0005594	collagen type IX trimer(GO:0005594)
3.3	3.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
3.2	16.2	GO:0043083	synaptic cleft(GO:0043083)
3.2	187.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
3.2	48.0	GO:0032809	neuronal cell body membrane(GO:0032809)
3.1	12.3	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
3.0	9.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
3.0	12.1	GO:0032591	dendritic spine membrane(GO:0032591)
2.9	8.7	GO:0032279	asymmetric synapse(GO:0032279)
2.8	16.7	GO:0002139	stereocilia coupling link(GO:0002139)
2.7	370.9	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
2.6	28.8	GO:0097440	apical dendrite(GO:0097440)
2.6	5.2	GO:0097413	Lewy body(GO:0097413)
2.6	10.3	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
2.5	20.3	GO:0032590	dendrite membrane(GO:0032590)
2.5	42.1	GO:0044295	axonal growth cone(GO:0044295)
2.4	243.7	GO:0045211	postsynaptic membrane(GO:0045211)
2.3	4.7	GO:0043219	lateral loop(GO:0043219)
2.2	2.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.2	10.8	GO:0070695	FHF complex(GO:0070695)
2.2	2.2	GO:0042585	germinal vesicle(GO:0042585)
2.1	177.0	GO:0030426	growth cone(GO:0030426)
2.1	24.8	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
2.0	14.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.0	6.0	GO:0036396	MIS complex(GO:0036396)
2.0	11.9	GO:0016600	flotillin complex(GO:0016600)
2.0	7.9	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.9	11.5	GO:0060077	inhibitory synapse(GO:0060077)
1.9	18.9	GO:0031045	dense core granule(GO:0031045)
1.9	22.7	GO:0034704	calcium channel complex(GO:0034704)
1.9	7.5	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
1.8	23.9	GO:0043198	dendritic shaft(GO:0043198)
1.8	7.3	GO:0045098	type III intermediate filament(GO:0045098)
1.8	12.7	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.8	62.5	GO:0098794	postsynapse(GO:0098794)
1.8	14.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.7	5.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
1.7	6.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.7	3.3	GO:0005608	laminin-3 complex(GO:0005608)
1.6	6.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
1.5	4.6	GO:0048179	activin receptor complex(GO:0048179)
1.5	7.6	GO:0070531	BRCA1-A complex(GO:0070531)
1.5	6.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
1.5	8.8	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.5	7.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
1.4	4.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
1.4	2.8	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.4	9.7	GO:0060076	excitatory synapse(GO:0060076)
1.4	65.3	GO:0043195	terminal bouton(GO:0043195)
1.4	4.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
1.3	289.2	GO:0045202	synapse(GO:0045202)
1.3	11.8	GO:0000137	Golgi cis cisterna(GO:0000137)
1.3	7.8	GO:0030008	TRAPP complex(GO:0030008)
1.3	7.5	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.2	1.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
1.2	14.7	GO:0046930	pore complex(GO:0046930)
1.2	2.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.2	3.6	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.2	3.5	GO:0030427	site of polarized growth(GO:0030427)
1.1	4.5	GO:1990130	Iml1 complex(GO:1990130)
1.1	65.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
1.1	16.4	GO:0000930	gamma-tubulin complex(GO:0000930)
1.1	2.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.1	4.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.0	3.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
1.0	3.1	GO:1990075	periciliary membrane compartment(GO:1990075)
1.0	7.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.0	11.9	GO:0031597	cytosolic proteasome complex(GO:0031597)
1.0	28.1	GO:0005921	gap junction(GO:0005921)
1.0	5.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.9	9.3	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.9	2.8	GO:0071797	LUBAC complex(GO:0071797)
0.9	11.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.9	0.9	GO:0005818	aster(GO:0005818)
0.9	3.6	GO:0043202	lysosomal lumen(GO:0043202)
0.9	2.7	GO:0070939	Dsl1p complex(GO:0070939)
0.9	1.8	GO:0070765	gamma-secretase complex(GO:0070765)
0.8	2.5	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.8	1.7	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.8	2.5	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.8	4.9	GO:0070847	core mediator complex(GO:0070847)
0.8	1.6	GO:0005726	perichromatin fibrils(GO:0005726)
0.8	3.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.8	4.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.8	1.5	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.7	3.7	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.7	3.6	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.7	5.0	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.7	5.0	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.7	9.1	GO:0031082	BLOC complex(GO:0031082)
0.7	2.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7	7.5	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.7	6.7	GO:0031512	motile primary cilium(GO:0031512)
0.7	2.6	GO:0030314	junctional membrane complex(GO:0030314)
0.7	34.9	GO:0043204	perikaryon(GO:0043204)
0.6	5.0	GO:0061700	GATOR2 complex(GO:0061700)
0.6	2.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.6	1.8	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.6	2.4	GO:0071817	MMXD complex(GO:0071817)
0.6	8.4	GO:0070382	exocytic vesicle(GO:0070382)
0.6	3.0	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.6	2.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.6	1.8	GO:0032437	cuticular plate(GO:0032437)
0.6	1.7	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.5	1.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.5	4.3	GO:0036157	outer dynein arm(GO:0036157)
0.5	0.5	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.5	4.3	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.5	1.1	GO:0070852	cell body fiber(GO:0070852)
0.5	3.7	GO:0042405	nuclear inclusion body(GO:0042405)
0.5	3.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.5	7.0	GO:0001741	XY body(GO:0001741)
0.5	4.5	GO:0000813	ESCRT I complex(GO:0000813)
0.5	4.4	GO:0000815	ESCRT III complex(GO:0000815)
0.5	3.9	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5	1.9	GO:0031262	Ndc80 complex(GO:0031262)
0.5	3.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.5	1.4	GO:0031417	NatC complex(GO:0031417)
0.5	1.9	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.5	1.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.5	0.5	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.5	60.8	GO:0031225	anchored component of membrane(GO:0031225)
0.5	4.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.4	8.9	GO:0001917	photoreceptor inner segment(GO:0001917)
0.4	4.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.4	1.3	GO:0055087	Ski complex(GO:0055087)
0.4	1.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.4	15.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.4	2.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.4	2.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.4	0.8	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.4	3.5	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.4	1.6	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4	0.8	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.4	15.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.4	1.4	GO:0070545	PeBoW complex(GO:0070545)
0.4	21.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.4	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.4	1.8	GO:0001520	outer dense fiber(GO:0001520)
0.3	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.3	1.0	GO:0097543	ciliary inversin compartment(GO:0097543)
0.3	8.5	GO:0005801	cis-Golgi network(GO:0005801)
0.3	0.6	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.3	17.7	GO:0036477	somatodendritic compartment(GO:0036477)
0.3	1.5	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.3	0.9	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3	4.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	2.8	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.3	3.9	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.3	0.3	GO:0019814	immunoglobulin complex(GO:0019814)
0.3	2.7	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	0.8	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.3	32.5	GO:0030424	axon(GO:0030424)
0.2	2.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	0.7	GO:0071942	XPC complex(GO:0071942)
0.2	0.7	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.2	2.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	3.5	GO:0031201	SNARE complex(GO:0031201)
0.2	1.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.2	2.7	GO:0070822	Sin3-type complex(GO:0070822)
0.2	0.8	GO:0043159	acrosomal matrix(GO:0043159)
0.2	43.9	GO:0043005	neuron projection(GO:0043005)
0.2	5.0	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	2.1	GO:0035371	microtubule plus-end(GO:0035371)
0.2	0.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	0.5	GO:0042583	chromaffin granule(GO:0042583)
0.2	0.8	GO:0097255	R2TP complex(GO:0097255)
0.2	0.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2	1.6	GO:0044447	axoneme part(GO:0044447)
0.1	1.0	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1	0.7	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.9	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.4	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	0.4	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.5	GO:0070876	SOSS complex(GO:0070876)
0.1	1.1	GO:0000124	SAGA complex(GO:0000124)
0.1	0.4	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	1.5	GO:0000800	lateral element(GO:0000800)
0.1	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	1.5	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.1	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.1	0.3	GO:0034457	Mpp10 complex(GO:0034457)
0.1	0.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.4	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.7	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.1	0.1	GO:0097450	astrocyte end-foot(GO:0097450)
0.1	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.0	3.6	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.5	GO:0032040	small-subunit processome(GO:0032040)
0.0	78.5	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.0	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
24.3	72.9	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
17.1	51.3	GO:0097109	neuroligin family protein binding(GO:0097109)
13.7	13.7	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
13.5	54.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
11.3	33.8	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
10.6	42.4	GO:0032051	clathrin light chain binding(GO:0032051)
10.0	40.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
9.6	19.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
8.9	26.6	GO:0048763	calcium-induced calcium release activity(GO:0048763)
8.7	26.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
8.5	76.3	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
8.2	65.9	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
7.9	31.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
7.7	23.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
7.6	22.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
7.6	22.7	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
7.4	29.7	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
7.4	22.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
7.2	28.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
7.0	20.9	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
6.9	20.8	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
6.7	6.7	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
6.6	19.8	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
6.4	25.6	GO:0005042	netrin receptor activity(GO:0005042)
6.3	82.1	GO:0050811	GABA receptor binding(GO:0050811)
6.3	44.0	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
6.2	37.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
6.1	18.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
5.9	35.5	GO:0004385	guanylate kinase activity(GO:0004385)
5.8	17.3	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
5.7	80.0	GO:0008066	ionotropic glutamate receptor activity(GO:0004970) glutamate receptor activity(GO:0008066)
5.7	34.1	GO:0048495	Roundabout binding(GO:0048495)
5.7	17.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
5.6	72.7	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
5.6	27.9	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.5	5.5	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
5.4	26.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
5.2	10.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
5.1	15.2	GO:0070699	type II activin receptor binding(GO:0070699)
4.6	18.6	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
4.4	26.5	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
4.4	4.4	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
4.2	21.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
4.2	33.7	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
4.2	21.0	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
4.2	16.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
4.1	12.2	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
4.0	28.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
4.0	40.4	GO:0042577	lipid phosphatase activity(GO:0042577)
4.0	16.0	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
3.9	39.4	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
3.9	3.9	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
3.9	11.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
3.9	11.7	GO:0008046	axon guidance receptor activity(GO:0008046)
3.8	15.4	GO:0030911	TPR domain binding(GO:0030911)
3.8	18.9	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
3.8	15.1	GO:1904288	BAT3 complex binding(GO:1904288)
3.8	52.6	GO:0031402	sodium ion binding(GO:0031402)
3.7	52.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
3.7	14.7	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
3.6	18.2	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
3.6	67.8	GO:0017075	syntaxin-1 binding(GO:0017075)
3.4	37.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
3.3	43.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
3.3	13.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
3.3	16.3	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
3.2	9.6	GO:0042296	ISG15 transferase activity(GO:0042296)
3.2	12.8	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
3.2	6.4	GO:0001032	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
3.2	9.5	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
3.1	9.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
3.1	12.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
3.1	9.2	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
3.1	15.4	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
3.1	3.1	GO:0031711	bradykinin receptor binding(GO:0031711)
3.0	12.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
3.0	91.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
3.0	9.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
3.0	9.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
3.0	23.8	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
2.9	2.9	GO:0072542	protein phosphatase activator activity(GO:0072542)
2.9	5.8	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
2.8	8.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
2.8	22.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.8	11.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.8	38.8	GO:0016917	GABA receptor activity(GO:0016917)
2.7	16.4	GO:0034711	inhibin binding(GO:0034711)
2.7	8.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.7	19.0	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
2.7	5.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
2.7	16.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
2.7	10.7	GO:0034056	estrogen response element binding(GO:0034056)
2.6	18.5	GO:0003680	AT DNA binding(GO:0003680)
2.6	18.0	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
2.6	7.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.6	7.7	GO:0097108	hedgehog family protein binding(GO:0097108)
2.6	2.6	GO:0051378	serotonin binding(GO:0051378)
2.5	20.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
2.5	7.5	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
2.5	2.5	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
2.5	9.8	GO:0030955	potassium ion binding(GO:0030955)
2.4	14.7	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.4	9.7	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
2.4	16.8	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.4	9.6	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
2.4	4.8	GO:0045503	dynein light chain binding(GO:0045503)
2.4	9.4	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
2.3	14.1	GO:0019992	diacylglycerol binding(GO:0019992)
2.3	4.6	GO:0001727	lipid kinase activity(GO:0001727)
2.3	13.6	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.3	11.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.2	6.7	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
2.2	6.7	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.2	29.0	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
2.2	24.3	GO:0042043	neurexin family protein binding(GO:0042043)
2.2	6.6	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
2.2	19.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.2	2.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.2	43.9	GO:0045499	chemorepellent activity(GO:0045499)
2.2	8.8	GO:0070878	primary miRNA binding(GO:0070878)
2.2	13.1	GO:0016421	CoA carboxylase activity(GO:0016421)
2.2	56.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
2.2	4.3	GO:0050693	LBD domain binding(GO:0050693)
2.2	15.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
2.2	6.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.1	15.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
2.1	29.8	GO:0045295	gamma-catenin binding(GO:0045295)
2.1	6.3	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
2.1	10.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
2.0	20.3	GO:0008179	adenylate cyclase binding(GO:0008179)
2.0	22.2	GO:0005522	profilin binding(GO:0005522)
2.0	42.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.0	4.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
2.0	6.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
2.0	6.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.0	10.0	GO:0042609	CD4 receptor binding(GO:0042609)
2.0	3.9	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.9	3.9	GO:0004969	histamine receptor activity(GO:0004969)
1.9	1.9	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.9	30.0	GO:0005272	sodium channel activity(GO:0005272)
1.9	5.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.9	46.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
1.8	7.4	GO:0031750	D3 dopamine receptor binding(GO:0031750)
1.8	27.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
1.8	5.5	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
1.8	5.5	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.8	5.5	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
1.8	5.4	GO:0050816	phosphothreonine binding(GO:0050816)
1.8	10.8	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.8	55.7	GO:0015459	potassium channel regulator activity(GO:0015459)
1.8	7.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.7	5.2	GO:0016882	cyclo-ligase activity(GO:0016882)
1.7	8.7	GO:0015198	oligopeptide transporter activity(GO:0015198)
1.7	1.7	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.7	6.8	GO:0004985	opioid receptor activity(GO:0004985)
1.7	13.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.7	5.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
1.7	1.7	GO:0005502	11-cis retinal binding(GO:0005502)
1.7	15.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
1.7	8.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.7	3.3	GO:0097016	L27 domain binding(GO:0097016)
1.7	5.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.7	8.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.6	4.9	GO:0031708	endothelin B receptor binding(GO:0031708)
1.6	19.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.6	4.9	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.6	11.3	GO:0033691	sialic acid binding(GO:0033691)
1.6	6.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
1.6	1.6	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
1.6	4.7	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
1.6	7.9	GO:0004994	somatostatin receptor activity(GO:0004994)
1.6	4.7	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
1.6	23.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.5	13.9	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
1.5	9.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
1.5	4.6	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.5	4.5	GO:1990825	sequence-specific mRNA binding(GO:1990825)
1.5	6.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.5	2.9	GO:0043121	neurotrophin binding(GO:0043121)
1.5	1.5	GO:0002046	opsin binding(GO:0002046)
1.4	20.2	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
1.4	2.9	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
1.4	59.1	GO:0030276	clathrin binding(GO:0030276)
1.4	9.8	GO:0030957	Tat protein binding(GO:0030957)
1.4	5.6	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.4	44.3	GO:0019894	kinesin binding(GO:0019894)
1.4	26.1	GO:0030332	cyclin binding(GO:0030332)
1.4	5.5	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.4	4.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
1.4	6.8	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.4	1.4	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
1.3	2.7	GO:0035939	microsatellite binding(GO:0035939)
1.3	4.0	GO:0043919	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
1.3	1.3	GO:0032564	dATP binding(GO:0032564)
1.3	11.8	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
1.3	6.6	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
1.3	27.4	GO:0052714	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
1.3	3.9	GO:0005148	prolactin receptor binding(GO:0005148)
1.2	7.5	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
1.2	32.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
1.2	3.7	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.2	33.2	GO:0001540	beta-amyloid binding(GO:0001540)
1.2	2.5	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
1.2	25.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
1.2	6.1	GO:0004565	beta-galactosidase activity(GO:0004565)
1.2	2.4	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
1.2	25.5	GO:0071837	HMG box domain binding(GO:0071837)
1.2	12.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.2	6.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.2	4.8	GO:0070052	collagen V binding(GO:0070052)
1.2	3.6	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.2	29.8	GO:0030507	spectrin binding(GO:0030507)
1.2	3.6	GO:0071209	U7 snRNA binding(GO:0071209)
1.2	5.9	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.2	2.4	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
1.2	1.2	GO:0031705	bombesin receptor binding(GO:0031705)
1.2	3.5	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
1.2	5.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
1.2	5.8	GO:0004111	creatine kinase activity(GO:0004111)
1.1	4.6	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
1.1	4.6	GO:0097001	ceramide binding(GO:0097001)
1.1	4.5	GO:0008502	melatonin receptor activity(GO:0008502)
1.1	10.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.1	27.9	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
1.1	2.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
1.1	22.7	GO:0005540	hyaluronic acid binding(GO:0005540)
1.1	5.4	GO:0004031	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
1.1	47.1	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
1.1	21.3	GO:0003785	actin monomer binding(GO:0003785)
1.1	5.3	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
1.0	7.3	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
1.0	12.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
1.0	4.1	GO:0043237	laminin-1 binding(GO:0043237)
1.0	5.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
1.0	5.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.0	9.9	GO:0004143	diacylglycerol kinase activity(GO:0004143)
1.0	2.0	GO:0002134	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.0	4.9	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.0	2.9	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
1.0	32.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
1.0	22.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
1.0	1.9	GO:0009374	biotin binding(GO:0009374)
0.9	3.8	GO:0038064	collagen receptor activity(GO:0038064)
0.9	3.8	GO:0016018	cyclosporin A binding(GO:0016018)
0.9	6.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.9	20.4	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.9	21.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.9	2.7	GO:0018588	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.9	6.3	GO:0042923	neuropeptide binding(GO:0042923)
0.9	4.5	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.9	6.2	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.9	18.6	GO:0005537	mannose binding(GO:0005537)
0.9	2.6	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.9	14.1	GO:0008378	galactosyltransferase activity(GO:0008378)
0.9	2.6	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.9	2.6	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.9	12.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.9	2.6	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.9	6.8	GO:0004383	guanylate cyclase activity(GO:0004383)
0.8	45.5	GO:0051219	phosphoprotein binding(GO:0051219)
0.8	10.0	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.8	0.8	GO:0051870	methotrexate binding(GO:0051870)
0.8	2.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.8	3.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.8	20.6	GO:0043015	gamma-tubulin binding(GO:0043015)
0.8	2.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.8	22.1	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.8	4.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.8	10.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.8	0.8	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.8	8.8	GO:0008146	sulfotransferase activity(GO:0008146)
0.8	2.4	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.8	4.7	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.8	2.3	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.8	2.3	GO:0016015	morphogen activity(GO:0016015)
0.8	3.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.8	2.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.8	23.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.7	4.5	GO:0032027	myosin light chain binding(GO:0032027)
0.7	2.2	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.7	2.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.7	1.5	GO:0051185	coenzyme transporter activity(GO:0051185)
0.7	2.2	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.7	6.6	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.7	3.6	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.7	3.5	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.7	7.0	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.7	1.4	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.7	6.3	GO:0008242	omega peptidase activity(GO:0008242)
0.7	16.0	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.7	8.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.7	8.8	GO:0030275	LRR domain binding(GO:0030275)
0.7	23.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.7	6.1	GO:0009881	photoreceptor activity(GO:0009881)
0.7	1.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.7	10.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.7	3.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.7	1.3	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.7	3.3	GO:0034841	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.7	16.5	GO:0022839	ion gated channel activity(GO:0022839)
0.7	2.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.7	3.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.6	2.6	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.6	2.6	GO:0043842	Kdo transferase activity(GO:0043842)
0.6	9.6	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.6	3.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.6	7.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.6	6.1	GO:0015643	toxic substance binding(GO:0015643)
0.6	1.8	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.6	2.4	GO:0038100	nodal binding(GO:0038100)
0.6	4.7	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6	10.0	GO:0042166	acetylcholine binding(GO:0042166)
0.6	30.2	GO:0044325	ion channel binding(GO:0044325)
0.6	7.5	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.6	2.9	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.6	1.7	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.6	1.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.6	1.7	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.6	1.7	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.5	1.6	GO:0019776	Atg8 ligase activity(GO:0019776)
0.5	2.6	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.5	2.1	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.5	3.6	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.5	2.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5	4.5	GO:0051787	misfolded protein binding(GO:0051787)
0.5	1.0	GO:0051425	PTB domain binding(GO:0051425)
0.5	1.5	GO:0071723	lipopeptide binding(GO:0071723)
0.5	6.8	GO:0016805	dipeptidase activity(GO:0016805)
0.5	13.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	6.7	GO:0008266	poly(U) RNA binding(GO:0008266)
0.5	2.4	GO:0045545	syndecan binding(GO:0045545)
0.5	1.0	GO:0008142	oxysterol binding(GO:0008142)
0.5	6.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.5	1.8	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.5	1.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.4	1.3	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4	2.7	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4	1.3	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.4	3.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.4	2.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4	6.0	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.4	3.4	GO:0046625	sphingolipid binding(GO:0046625)
0.4	3.4	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4	4.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.4	2.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.4	33.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.4	1.7	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4	1.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.4	1.2	GO:0019808	polyamine binding(GO:0019808)
0.4	0.4	GO:0031420	alkali metal ion binding(GO:0031420)
0.4	8.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.4	2.0	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.4	1.2	GO:0008147	structural constituent of bone(GO:0008147)
0.4	4.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.4	1.6	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.4	1.5	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.4	1.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.4	3.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.4	1.1	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.3	2.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.3	1.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.3	0.3	GO:0015927	trehalase activity(GO:0015927)
0.3	0.3	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.3	3.7	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3	1.0	GO:0019862	IgA binding(GO:0019862)
0.3	0.9	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.3	2.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.3	0.9	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.3	0.3	GO:0031893	vasopressin receptor binding(GO:0031893)
0.3	0.6	GO:0070840	dynein complex binding(GO:0070840)
0.3	2.0	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.3	4.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	1.7	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.3	1.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.3	0.5	GO:0043398	HLH domain binding(GO:0043398)
0.3	2.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.3	0.3	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.3	1.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.3	3.3	GO:0051183	vitamin transporter activity(GO:0051183)
0.2	0.7	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.2	0.9	GO:0034452	dynactin binding(GO:0034452)
0.2	0.2	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.2	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.2	0.7	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2	5.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2	0.9	GO:0008932	lytic endotransglycosylase activity(GO:0008932)
0.2	2.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2	0.6	GO:0000403	Y-form DNA binding(GO:0000403)
0.2	1.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	0.6	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2	0.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	3.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.2	1.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.2	0.4	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.2	0.5	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	0.5	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.2	0.7	GO:0051434	BH3 domain binding(GO:0051434)
0.2	0.2	GO:0001884	pyrimidine nucleoside binding(GO:0001884)
0.2	0.5	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	74.4	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.2	1.5	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.4	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.3	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	5.1	GO:0044824	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.9	GO:0031386	protein tag(GO:0031386)
0.1	3.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	2.4	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	0.2	GO:0016631	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.1	0.6	GO:0051920	peroxiredoxin activity(GO:0051920)
0.1	4.3	GO:0051082	unfolded protein binding(GO:0051082)
0.1	0.3	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.8	GO:0004629	phospholipase C activity(GO:0004629)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.4	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.1	2.0	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	0.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.2	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.2	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	1.9	GO:0016415	octanoyltransferase activity(GO:0016415)
0.1	0.1	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1	0.3	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	13.0	GO:0005549	odorant binding(GO:0005549)
0.0	0.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	1.4	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.0	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.0	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.6	146.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
3.0	27.1	PID S1P S1P4 PATHWAY	S1P4 pathway
2.7	2.7	ST ADRENERGIC	Adrenergic Pathway
2.2	2.2	PID IGF1 PATHWAY	IGF1 pathway
2.1	41.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
2.0	13.7	PID ALK2 PATHWAY	ALK2 signaling events
1.9	27.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.9	26.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.8	51.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.8	3.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.5	12.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
1.2	44.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
1.0	19.7	PID SHP2 PATHWAY	SHP2 signaling
1.0	8.1	ST G ALPHA S PATHWAY	G alpha s Pathway
1.0	10.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
1.0	23.7	PID REELIN PATHWAY	Reelin signaling pathway
1.0	20.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.9	15.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.9	7.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.9	3.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.9	9.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.9	26.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.9	8.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.8	5.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8	5.5	PID IL3 PATHWAY	IL3-mediated signaling events
0.8	12.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.7	22.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.6	21.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.6	15.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.6	2.9	PID EPHB FWD PATHWAY	EPHB forward signaling
0.6	0.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5	22.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.5	4.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.5	10.2	PID CDC42 PATHWAY	CDC42 signaling events
0.4	1.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.4	14.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.4	12.3	PID INSULIN PATHWAY	Insulin Pathway
0.4	12.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	7.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.3	4.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.3	3.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.2	2.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	3.8	PID ARF 3PATHWAY	Arf1 pathway
0.2	7.9	PID LKB1 PATHWAY	LKB1 signaling events
0.2	0.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	8.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.9	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	0.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	1.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	14.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.6	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	84.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
6.8	101.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
6.5	6.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
6.2	99.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
5.5	76.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
5.1	71.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
4.9	48.6	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
4.5	49.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
4.5	49.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
4.3	12.9	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
4.0	43.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
3.5	38.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
3.4	145.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
3.2	3.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
3.2	101.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
3.1	70.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
3.0	56.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
2.8	39.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
2.8	28.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
2.8	16.6	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
2.7	2.7	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
2.7	32.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
2.6	33.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
2.6	2.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.5	17.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.5	5.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
2.3	29.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
2.1	17.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
2.1	2.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
1.9	100.2	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.9	41.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
1.8	20.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.8	32.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.8	23.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.8	34.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.8	25.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
1.8	8.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
1.7	27.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
1.7	24.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
1.7	11.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.6	20.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.5	1.5	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
1.4	23.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
1.4	25.9	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
1.4	2.9	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.4	5.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
1.4	16.6	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
1.4	22.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
1.3	25.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
1.3	13.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.3	5.3	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
1.3	18.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
1.3	46.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.2	4.9	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.2	4.8	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
1.2	20.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
1.2	33.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.2	9.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.2	12.7	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
1.2	10.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.1	4.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.1	3.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
1.0	19.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
1.0	4.8	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.9	13.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.9	0.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.9	17.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.9	13.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.9	1.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.8	12.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.8	9.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.8	4.0	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.8	3.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.8	0.8	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.7	3.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.7	11.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7	30.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.7	1.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.7	19.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.7	12.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7	11.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.7	4.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.6	7.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.6	7.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.6	5.7	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.6	5.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.6	11.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.6	6.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.6	6.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6	6.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.6	4.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.5	6.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.5	6.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5	30.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.5	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	9.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.5	0.5	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.5	4.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.5	6.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.4	15.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.4	1.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.4	4.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.4	4.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.4	5.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.4	3.4	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.4	8.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.4	0.7	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.4	3.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.4	3.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.3	5.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	1.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.3	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.3	4.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	16.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.3	2.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.3	1.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.3	1.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	2.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.3	2.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.2	3.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	0.2	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2	0.6	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.2	3.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	0.8	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.2	9.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	21.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	2.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	0.3	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	1.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	0.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1

Results for Hic2

Z-value: 13.22

Motif logo

Transcription factors associated with Hic2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hic2 motif across conditions

Conditions sorted by the z-value of the Hic2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: