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ENCODE: ATAC-seq of different tissues during embryonic development
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Results for Hlx

Z-value: 0.82

Motif logo

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Transcription factors associated with Hlx

Gene Symbol Gene ID Gene Info
Hlx
ENSMUSG00000039377.6 H2.0-like homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_184727788_184727992Hlx37080.171022-0.247.7e-02Click!
chr1_184731813_184732486Hlx4700.749555-0.152.9e-01Click!
chr1_184727523_184727685Hlx39940.166076-0.143.0e-01Click!
chr1_184732596_184733212Hlx2850.8708810.095.0e-01Click!
chr1_184733319_184733470Hlx7750.552845-0.038.5e-01Click!

Activity of the Hlx motif across conditions

Conditions sorted by the z-value of the Hlx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_117897075_117897226 3.87 4933411E08Rik
 RIKEN cDNA 4933411E08 gene
 28309
 0.12
chr2_119566179_119566455 3.76 Chp1
 calcineurin-like EF hand protein 1
 288
 0.85
chr1_177475904_177476057 3.63 Gm37306
 predicted gene, 37306
 8602
 0.17
chrX_93831605_93832731 3.58 Pdk3
 pyruvate dehydrogenase kinase, isoenzyme 3
 33
 0.98
chr19_43767999_43768210 3.53 Cutc
 cutC copper transporter
 3231
 0.18
chr4_117136303_117136464 3.49 Plk3
 polo like kinase 3
 2420
 0.1
chr16_78040391_78040542 2.74 Gm25025
 predicted gene, 25025
 10251
 0.23
chr10_69253249_69253618 2.40 Rhobtb1
 Rho-related BTB domain containing 1
 12204
 0.19
chr13_62952253_62952404 2.40 Gm48812
 predicted gene, 48812
 2886
 0.22
chr4_49451596_49451772 2.39 Acnat1
 acyl-coenzyme A amino acid N-acyltransferase 1
 547
 0.69
chr13_47111196_47111529 2.37 1700026N04Rik
 RIKEN cDNA 1700026N04 gene
 4943
 0.13
chr13_93234781_93234932 2.25 Tent2
 terminal nucleotidyltransferase 2
 42471
 0.12
chr4_14273616_14273932 2.15 Gm24908
 predicted gene, 24908
 34156
 0.18
chr3_108771125_108771338 2.14 Aknad1
 AKNA domain containing 1
 11017
 0.15
chr11_4095576_4095728 2.11 Mtfp1
 mitochondrial fission process 1
 207
 0.87
chr3_34504199_34504577 2.10 Gm29135
 predicted gene 29135
 22181
 0.16
chr15_98608664_98610204 2.09 Adcy6
 adenylate cyclase 6
 598
 0.55
chr7_45103031_45103408 2.04 Fcgrt
 Fc receptor, IgG, alpha chain transporter
 133
 0.83
chr10_125785483_125786054 2.02 Lrig3
 leucine-rich repeats and immunoglobulin-like domains 3
 180400
 0.03
chr5_136739184_136739335 1.86 Col26a1
 collagen, type XXVI, alpha 1
 5290
 0.23
chrX_10877865_10878215 1.71 Gm14473
 predicted gene 14473
 12407
 0.26
chr13_36202916_36203067 1.63 Gm48765
 predicted gene, 48765
 13268
 0.16
chr1_59212186_59212347 1.59 Als2
 alsin Rho guanine nucleotide exchange factor
 6860
 0.17
chr10_120387024_120387466 1.57 9230105E05Rik
 RIKEN cDNA 9230105E05 gene
 2278
 0.28
chr16_44672098_44672717 1.57 Nepro
 nucleolus and neural progenitor protein
 51894
 0.11
chr8_125782363_125782518 1.54 Pcnx2
 pecanex homolog 2
 8312
 0.24
chr13_101427845_101427996 1.52 Gm36994
 predicted gene, 36994
 15331
 0.2
chr1_162020499_162020732 1.49 2810442N19Rik
 RIKEN cDNA 2810442N19 gene
 15443
 0.14
chr7_75761095_75761254 1.43 Gm23251
 predicted gene, 23251
 3806
 0.19
chr9_113833592_113833892 1.42 Clasp2
 CLIP associating protein 2
 21142
 0.2
chr4_132072343_132072494 1.39 Epb41
 erythrocyte membrane protein band 4.1
 321
 0.8
chr11_78401648_78401948 1.39 Slc13a2os
 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, opposite strand
 7313
 0.1
chr2_170091681_170092036 1.37 Zfp217
 zinc finger protein 217
 39362
 0.2
chr13_63039019_63039172 1.36 Aopep
 aminopeptidase O
 23602
 0.15
chr4_154359614_154359823 1.33 Prdm16
 PR domain containing 16
 11261
 0.18
chr1_36670453_36670635 1.32 Gm24133
 predicted gene, 24133
 6579
 0.12
chr14_7896790_7896982 1.30 Flnb
 filamin, beta
 12145
 0.19
chr17_56036249_56036917 1.26 Sh3gl1
 SH3-domain GRB2-like 1
 7
 0.94
chr14_21462396_21462784 1.25 Gm30363
 predicted gene, 30363
 8831
 0.19
chr2_60142673_60142824 1.25 Ldha-ps
 lactate dehydrogenase A, pseudogene
 8693
 0.16
chr19_24534375_24534662 1.22 Pip5k1b
 phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
 21271
 0.17
chr14_122909784_122909949 1.22 4930594M22Rik
 RIKEN cDNA 4930594M22 gene
 3164
 0.2
chr9_32545148_32545570 1.21 Fli1
 Friend leukemia integration 1
 2498
 0.19
chr13_14040175_14040467 1.21 Tbce
 tubulin-specific chaperone E
 683
 0.47
chr6_71130459_71130610 1.20 Thnsl2
 threonine synthase-like 2 (bacterial)
 1438
 0.31
chr8_110022869_110023026 1.20 Gm45888
 predicted gene 45888
 8623
 0.12
chr7_75863314_75863477 1.20 Klhl25
 kelch-like 25
 14954
 0.22
chr10_53101557_53101708 1.19 Gm47622
 predicted gene, 47622
 911
 0.65
chr2_85172390_85172701 1.17 Gm13713
 predicted gene 13713
 11767
 0.11
chr13_43480925_43481874 1.17 Ranbp9
 RAN binding protein 9
 117
 0.95
chr11_3170338_3170795 1.13 Sfi1
 Sfi1 homolog, spindle assembly associated (yeast)
 138
 0.93
chr4_97601207_97601387 1.13 E130114P18Rik
 RIKEN cDNA E130114P18 gene
 16661
 0.23
chr14_19707913_19708072 1.13 Gm49341
 predicted gene, 49341
 10783
 0.13
chr5_21264473_21264673 1.10 Gsap
 gamma-secretase activating protein
 13414
 0.16
chr18_56871340_56871513 1.10 Gm18087
 predicted gene, 18087
 44662
 0.14
chr4_137481273_137481486 1.09 Hspg2
 perlecan (heparan sulfate proteoglycan 2)
 12576
 0.13
chr10_71338295_71338446 1.08 Cisd1
 CDGSH iron sulfur domain 1
 6584
 0.14
chr13_62888714_62888865 1.06 Fbp1
 fructose bisphosphatase 1
 507
 0.73
chr5_103753230_103754272 1.06 Aff1
 AF4/FMR2 family, member 1
 411
 0.87
chr12_47466088_47466239 1.05 Gm48578
 predicted gene, 48578
 66094
 0.15
chr15_102753205_102753442 1.02 Calcoco1
 calcium binding and coiled coil domain 1
 31145
 0.11
chr2_167713774_167713925 1.02 A530013C23Rik
 RIKEN cDNA A530013C23 gene
 22668
 0.1
chr16_45924188_45924367 1.01 Gm15640
 predicted gene 15640
 12046
 0.17
chr15_7625219_7625370 1.01 Gm37743
 predicted gene, 37743
 45046
 0.15
chr11_69418367_69419708 0.99 Kdm6b
 KDM1 lysine (K)-specific demethylase 6B
 5362
 0.09
chr1_84993310_84993634 0.99 Gm29284
 predicted gene 29284
 440
 0.72
chr2_151976038_151976372 0.98 Fam110a
 family with sequence similarity 110, member A
 2239
 0.21
chr6_143142224_143142402 0.98 Gm44306
 predicted gene, 44306
 7226
 0.14
chr2_155894841_155894992 0.98 Uqcc1
 ubiquinol-cytochrome c reductase complex assembly factor 1
 15688
 0.12
chr8_94898997_94899206 0.97 Ccdc102a
 coiled-coil domain containing 102A
 18420
 0.1
chr4_137858517_137858672 0.96 Ece1
 endothelin converting enzyme 1
 3643
 0.24
chr16_25293836_25294037 0.96 Tprg
 transformation related protein 63 regulated
 7115
 0.32
chr6_140147796_140147947 0.95 Gm44159
 predicted gene, 44159
 15804
 0.17
chr15_75863041_75863192 0.93 Gsdmd
 gasdermin D
 737
 0.46
chr2_109995179_109995348 0.92 Lgr4
 leucine-rich repeat-containing G protein-coupled receptor 4
 5265
 0.22
chr4_142049656_142049814 0.91 Gm13053
 predicted gene 13053
 1157
 0.39
chr1_85615441_85615607 0.90 Gm10552
 predicted gene 10552
 3628
 0.12
chr6_25664249_25664412 0.90 Gpr37
 G protein-coupled receptor 37
 25462
 0.25
chr1_66922212_66922363 0.90 Myl1
 myosin, light polypeptide 1
 12411
 0.12
chr2_171734745_171734896 0.86 1700028P15Rik
 RIKEN cDNA 1700028P15 gene
 227311
 0.02
chr1_88491666_88491830 0.86 Glrp1
 glutamine repeat protein 1
 18318
 0.14
chr9_63201505_63201702 0.84 Skor1
 SKI family transcriptional corepressor 1
 52642
 0.12
chr2_18586936_18587492 0.84 Gm13353
 predicted gene 13353
 19088
 0.18
chr14_16962435_16962707 0.82 Gm18078
 predicted gene, 18078
 8965
 0.24
chr11_62605415_62606716 0.82 Lrrc75aos2
 leucine rich repeat containing 75A, opposite strand 2
 298
 0.72
chr1_80408527_80409167 0.82 Gm6189
 predicted gene 6189
 23662
 0.13
chr7_100559420_100559571 0.81 Mrpl48
 mitochondrial ribosomal protein L48
 11875
 0.09
chr1_45767537_45767744 0.81 Gm8307
 predicted gene 8307
 697
 0.6
chr7_6781231_6781382 0.81 Mir3099
 microRNA 3099
 22281
 0.09
chr7_137306238_137306389 0.80 Ebf3
 early B cell factor 3
 7603
 0.2
chr17_25127767_25127933 0.79 Clcn7
 chloride channel, voltage-sensitive 7
 5541
 0.1
chr9_50501327_50501514 0.79 Plet1os
 placenta expressed transcript 1, opposite strand
 3385
 0.16
chr1_176995106_176995337 0.78 Sdccag8
 serologically defined colon cancer antigen 8
 2788
 0.21
chr1_85032083_85032289 0.77 AC167036.2
 novel protein
 3342
 0.13
chr5_151046930_151047128 0.77 Gm8675
 predicted gene 8675
 37728
 0.16
chrX_38473528_38474265 0.77 Gm7598
 predicted gene 7598
 2565
 0.27
chr14_17786377_17786528 0.77 Gm48320
 predicted gene, 48320
 15330
 0.28
chr2_172261099_172261318 0.75 Mc3r
 melanocortin 3 receptor
 12716
 0.17
chr3_28060860_28061033 0.75 Pld1
 phospholipase D1
 8568
 0.28
chr2_170158021_170158172 0.74 Zfp217
 zinc finger protein 217
 9993
 0.28
chr1_98147453_98147604 0.74 1810006J02Rik
 RIKEN cDNA 1810006J02 gene
 16061
 0.18
chr7_101837492_101838185 0.73 Inppl1
 inositol polyphosphate phosphatase-like 1
 35
 0.49
chr1_130732805_130732969 0.73 AA986860
 expressed sequence AA986860
 777
 0.43
chr10_128336232_128336487 0.72 Cs
 citrate synthase
 1375
 0.18
chr10_20046153_20046446 0.72 Map3k5
 mitogen-activated protein kinase kinase kinase 5
 53226
 0.13
chr3_115660838_115661123 0.72 S1pr1
 sphingosine-1-phosphate receptor 1
 54092
 0.13
chr4_106909039_106909761 0.71 Ssbp3
 single-stranded DNA binding protein 3
 1301
 0.48
chr14_117674551_117674852 0.70 Mir6239
 microRNA 6239
 279146
 0.01
chr1_166002288_166003185 0.69 Pou2f1
 POU domain, class 2, transcription factor 1
 58
 0.72
chr12_75826912_75827184 0.69 Syne2
 spectrin repeat containing, nuclear envelope 2
 8698
 0.25
chr11_4553637_4553951 0.68 Mtmr3
 myotubularin related protein 3
 7526
 0.17
chr1_192823078_192823550 0.66 Gm38360
 predicted gene, 38360
 2187
 0.22
chr12_103969871_103970197 0.65 Serpina1e
 serine (or cysteine) peptidase inhibitor, clade A, member 1E
 11059
 0.1
chr6_134147989_134148473 0.64 Gm17088
 predicted gene 17088
 23776
 0.18
chr7_65803210_65803361 0.64 1810008I18Rik
 RIKEN cDNA 1810008I18 gene
 174
 0.95
chr1_64087943_64089121 0.63 Gm13748
 predicted gene 13748
 9878
 0.19
chr17_47914586_47915244 0.63 Gm15556
 predicted gene 15556
 7463
 0.14
chr10_18370345_18371012 0.63 Nhsl1
 NHS-like 1
 19644
 0.19
chr3_60500259_60500437 0.62 Mbnl1
 muscleblind like splicing factor 1
 587
 0.8
chr2_93008105_93008300 0.62 Prdm11
 PR domain containing 11
 5708
 0.22
chr11_105549454_105549608 0.62 Tanc2
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
 40455
 0.15
chr7_19119292_19119545 0.61 Fbxo46
 F-box protein 46
 441
 0.56
chr13_22020931_22021318 0.61 Gm11290
 predicted gene 11290
 3618
 0.06
chr12_109552974_109553125 0.61 Meg3
 maternally expressed 3
 3794
 0.05
chr6_89291609_89291772 0.61 4930512J16Rik
 RIKEN cDNA 4930512J16 gene
 5965
 0.14
chr2_34825635_34825786 0.60 Fbxw2
 F-box and WD-40 domain protein 2
 312
 0.82
chr17_78327187_78327654 0.60 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 23469
 0.16
chr19_9924707_9924858 0.59 Gm36913
 predicted gene, 36913
 3752
 0.1
chr17_78273911_78274066 0.59 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 6195
 0.2
chr12_52671451_52671886 0.58 Akap6
 A kinase (PRKA) anchor protein 6
 27715
 0.15
chr12_37142164_37142324 0.58 Meox2
 mesenchyme homeobox 2
 33704
 0.16
chr8_104365772_104365923 0.58 Gm45877
 predicted gene 45877
 2179
 0.16
chr2_178610675_178610841 0.57 Cdh26
 cadherin-like 26
 150128
 0.04
chr11_53818750_53818901 0.57 Gm12216
 predicted gene 12216
 22950
 0.11
chr18_23748563_23748754 0.57 Gm15972
 predicted gene 15972
 3647
 0.2
chr3_95517252_95517598 0.56 Ctss
 cathepsin S
 9361
 0.1
chr11_98925326_98925710 0.56 Rara
 retinoic acid receptor, alpha
 2300
 0.17
chr12_54985296_54986516 0.56 Baz1a
 bromodomain adjacent to zinc finger domain 1A
 30
 0.91
chr18_5002577_5002904 0.55 Svil
 supervillin
 7804
 0.3
chr3_129296851_129297002 0.55 Gm42628
 predicted gene 42628
 11657
 0.16
chr14_65737090_65737241 0.55 Scara5
 scavenger receptor class A, member 5
 60688
 0.1
chr11_29547325_29547986 0.54 Rps27a
 ribosomal protein S27A
 205
 0.59
chr4_132874359_132874577 0.54 Stx12
 syntaxin 12
 10041
 0.12
chr17_30611617_30611888 0.54 Glo1
 glyoxalase 1
 817
 0.45
chr18_78350420_78350571 0.54 Gm6133
 predicted gene 6133
 741
 0.78
chr12_112333322_112333806 0.53 Gm38123
 predicted gene, 38123
 16503
 0.18
chr13_95777279_95777613 0.53 Iqgap2
 IQ motif containing GTPase activating protein 2
 13049
 0.19
chr12_105757874_105758401 0.53 Ak7
 adenylate kinase 7
 12862
 0.17
chrX_96134190_96134604 0.53 Gm24718
 predicted gene, 24718
 16575
 0.18
chr1_180179935_180180086 0.53 Coq8a
 coenzyme Q8A
 1088
 0.44
chr10_115263315_115263511 0.53 Gm8942
 predicted gene 8942
 6565
 0.17
chr1_136911165_136911329 0.53 Nr5a2
 nuclear receptor subfamily 5, group A, member 2
 29336
 0.18
chr4_43598778_43598951 0.52 Gm12472
 predicted gene 12472
 10792
 0.07
chr13_37859595_37859751 0.52 Rreb1
 ras responsive element binding protein 1
 1739
 0.39
chr2_174291748_174291899 0.52 Gnasas1
 GNAS antisense RNA 1
 3566
 0.16
chr11_47188652_47188809 0.52 Sgcd
 sarcoglycan, delta (dystrophin-associated glycoprotein)
 190792
 0.03
chr17_86301671_86301829 0.51 2010106C02Rik
 RIKEN cDNA 2010106C02 gene
 14572
 0.27
chr12_79532095_79532284 0.51 Rad51b
 RAD51 paralog B
 204836
 0.02
chr2_167902375_167902526 0.51 Ptpn1
 protein tyrosine phosphatase, non-receptor type 1
 29607
 0.14
chr10_127355403_127355866 0.50 Inhbe
 inhibin beta-E
 1223
 0.25
chr18_74854672_74855018 0.50 Gm24559
 predicted gene, 24559
 51589
 0.08
chr16_95924762_95924926 0.50 1600002D24Rik
 RIKEN cDNA 1600002D24 gene
 4233
 0.21
chr13_42342256_42342434 0.50 Gm47118
 predicted gene, 47118
 37354
 0.17
chr12_117250438_117250838 0.49 Mir153
 microRNA 153
 179
 0.97
chr2_131254315_131254509 0.49 Pank2
 pantothenate kinase 2
 8083
 0.11
chr6_144902234_144902547 0.49 Gm22792
 predicted gene, 22792
 98758
 0.06
chr5_25064693_25064847 0.49 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 35872
 0.13
chr1_151580285_151580566 0.48 Fam129a
 family with sequence similarity 129, member A
 8929
 0.17
chr17_56688104_56688477 0.48 Ranbp3
 RAN binding protein 3
 8445
 0.11
chr2_134350455_134350845 0.48 Hao1
 hydroxyacid oxidase 1, liver
 203657
 0.03
chr15_64026966_64027117 0.48 Gm25628
 predicted gene, 25628
 1093
 0.51
chr5_15487606_15487855 0.48 Gm21149
 predicted gene, 21149
 11207
 0.16
chr7_35116059_35116210 0.48 Cebpa
 CCAAT/enhancer binding protein (C/EBP), alpha
 3159
 0.12
chr3_55075221_55075624 0.48 Gm43555
 predicted gene 43555
 17766
 0.13
chr11_22348041_22348563 0.47 Ehbp1
 EH domain binding protein 1
 6010
 0.25
chr9_104071426_104071577 0.47 Acad11
 acyl-Coenzyme A dehydrogenase family, member 11
 7768
 0.1
chr9_69291313_69291464 0.47 Rora
 RAR-related orphan receptor alpha
 1706
 0.45
chr1_17655681_17656007 0.47 Gm28154
 predicted gene 28154
 14763
 0.2
chr17_84777000_84777216 0.46 Lrpprc
 leucine-rich PPR-motif containing
 435
 0.81
chr11_105125823_105126961 0.46 Mettl2
 methyltransferase like 2
 33
 0.97
chr8_109567958_109568109 0.46 Txnl4b
 thioredoxin-like 4B
 855
 0.48
chr9_79869537_79869690 0.46 Gm20477
 predicted gene 20477
 31226
 0.13
chr16_36707794_36708006 0.46 Ildr1
 immunoglobulin-like domain containing receptor 1
 7638
 0.14
chr8_64746788_64747015 0.45 Klhl2
 kelch-like 2, Mayven
 8070
 0.16
chr8_25772876_25773027 0.45 Bag4
 BCL2-associated athanogene 4
 4631
 0.11
chr10_102895997_102896156 0.45 Gm5175
 predicted gene 5175
 76705
 0.1
chr4_141734704_141734869 0.45 Ddi2
 DNA-damage inducible protein 2
 11367
 0.12
chr19_14596815_14596966 0.44 Tle4
 transducin-like enhancer of split 4
 1161
 0.62
chr1_54913082_54913233 0.44 A130048G24Rik
 RIKEN cDNA A130048G24 gene
 3437
 0.24
chr14_41115323_41115474 0.44 Mat1a
 methionine adenosyltransferase I, alpha
 10017
 0.12
chr15_58796543_58796694 0.44 Gm20712
 predicted gene 20712
 14667
 0.14
chr4_74401736_74401893 0.43 Kdm4c
 lysine (K)-specific demethylase 4C
 139004
 0.04
chr16_52446109_52446270 0.43 Alcam
 activated leukocyte cell adhesion molecule
 6276
 0.33
chr13_80623585_80623746 0.43 Gm46388
 predicted gene, 46388
 130656
 0.05
chr9_122074963_122075114 0.43 Gm39465
 predicted gene, 39465
 23575
 0.1
chr19_55110604_55110837 0.42 Gpam
 glycerol-3-phosphate acyltransferase, mitochondrial
 7629
 0.21
chr4_146482529_146482708 0.41 Gm13245
 predicted gene 13245
 1951
 0.25
chr1_136228974_136229345 0.41 Inava
 innate immunity activator
 860
 0.42
chr2_167799405_167799696 0.40 9230111E07Rik
 RIKEN cDNA 9230111E07 gene
 17497
 0.14
chr9_115243693_115243977 0.40 Stmn1-rs1
 stathmin 1, related sequence 1
 38146
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8 3.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2 1.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.2 0.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 1.1 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.2 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 0.4 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.5 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 2.1 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.4 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.6 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.0 GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.1 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 1.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.2 GO:0022615 protein to membrane docking(GO:0022615)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.0 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.0 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 1.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.0 GO:0048208 trophectodermal cellular morphogenesis(GO:0001831) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.0 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.0 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0071651 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:2001260 regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0 0.0 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0061325 cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0051256 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.0 GO:0015677 copper ion import(GO:0015677) ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.3 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 1.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.2 GO:0032010 phagolysosome(GO:0032010)
0.1 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:1990752 microtubule end(GO:1990752)
0.0 0.0 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 3.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 1.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 1.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.8 GO:0018031 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.1 0.2 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 3.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.3 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.4 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:1990188 euchromatin binding(GO:1990188)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling