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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Hoxb2_Dlx2

Z-value: 5.48

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Transcription factors associated with Hoxb2_Dlx2

Gene Symbol	Gene ID	Gene Info
Hoxb2 Ensembl NCBI MGI UniProt	ENSMUSG00000075588.5	homeobox B2
Dlx2 Ensembl NCBI MGI UniProt	ENSMUSG00000023391.7	distal-less homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_71612412_71612753	Dlx2	65828	0.080269	0.92	1.2e-22	Click!
chr2_71625343_71625591	Dlx2	78713	0.064943	0.88	7.2e-19	Click!
chr2_71625624_71625819	Dlx2	78967	0.064665	0.86	3.7e-17	Click!
chr2_71546298_71546639	Dlx2	286	0.874145	0.83	4.0e-15	Click!
chr2_71630055_71630257	Dlx2	83402	0.059955	0.83	7.9e-15	Click!
chr11_96349606_96349757	Hoxb2	844	0.334222	-0.20	1.5e-01	Click!
chr11_96352663_96352814	Hoxb2	1107	0.253350	-0.15	2.6e-01	Click!
chr11_96351442_96351613	Hoxb2	104	0.912927	0.14	2.9e-01	Click!
chr11_96351824_96352086	Hoxb2	324	0.735016	-0.10	4.6e-01	Click!

Activity of the Hoxb2_Dlx2 motif across conditions

Conditions sorted by the z-value of the Hoxb2_Dlx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_139885937_139886924	63.62	Gm43678	predicted gene 43678	73666	0.11
chr17_11927079_11927230	57.95	Prkn	parkin RBR E3 ubiquitin protein ligase	81944	0.1
chr18_23036938_23037296	57.44	Nol4	nucleolar protein 4	1539	0.55
chr9_22826534_22827067	55.98	Gm27639	predicted gene, 27639	53965	0.15
chrX_169838405_169838582	55.97	Mid1	midline 1	10334	0.25
chr3_66102086_66102567	55.54	Gm36973	predicted gene, 36973	2521	0.19
chr4_87739581_87739778	54.44	Mllt3	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3	66615	0.13
chr13_99444397_99444879	53.93	Map1b	microtubule-associated protein 1B	171	0.95
chr15_40114597_40115428	52.44	9330182O14Rik	RIKEN cDNA 9330182O14 gene	19353	0.17
chr18_74956688_74957137	49.10	Lipg	lipase, endothelial	4350	0.11
chr13_83739197_83739995	48.59	C130071C03Rik	RIKEN cDNA C130071C03 gene	733	0.33
chr13_73117014_73117369	47.84	Rpl31-ps2	ribosomal protein L31, pseudogene 2	116204	0.06
chr12_44839950_44840386	47.27	Gm15901	predicted gene 15901	83012	0.1
chr16_7448068_7448264	47.16	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	95196	0.1
chr8_58372581_58372772	47.11	Gm45635	predicted gene 45635	126089	0.06
chr3_40673604_40673797	46.46	Intu	inturned planar cell polarity protein	1079	0.49
chr2_72426764_72427187	46.34	Cdca7	cell division cycle associated 7	49184	0.13
chr2_168343654_168344081	45.84	Gm22704	predicted gene, 22704	8167	0.18
chr7_64884497_64884825	45.32	Nsmce3	NSE3 homolog, SMC5-SMC6 complex component	11664	0.22
chr17_93377556_93377754	44.20	Gm50001	predicted gene, 50001	14043	0.22
chr15_4378780_4379184	43.95	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3	3478	0.36
chr12_51002047_51002408	43.62	Gm40421	predicted gene, 40421	2646	0.28
chr7_78887666_78887880	42.77	Mir7-2	microRNA 7-2	504	0.68
chr1_46830172_46830391	42.76	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5618	0.22
chr8_92545686_92545926	42.26	Gm45336	predicted gene 45336	80039	0.09
chr3_21357187_21357372	42.11	Gm29137	predicted gene 29137	88189	0.1
chr10_70458638_70458831	41.77	Fam13c	family with sequence similarity 13, member C	17808	0.19
chr4_24429638_24429836	41.37	Gm27243	predicted gene 27243	1153	0.54
chr4_85768203_85768551	40.90	Adamtsl1	ADAMTS-like 1	254050	0.02
chr3_78792451_78792970	40.90	Gm18952	predicted gene, 18952	34091	0.19
chr5_111195506_111196004	40.68	Gm43676	predicted gene 43676	1385	0.43
chr2_56257440_56257969	40.61	Gm13518	predicted gene 13518	217851	0.02
chr2_132427639_132427949	40.32	4921508D12Rik	RIKEN cDNA 4921508D12 gene	3053	0.25
chr2_165076987_165077575	39.68	1700025C18Rik	RIKEN cDNA 1700025C18 gene	13469	0.14
chr5_42067440_42068088	39.67	Gm16223	predicted gene 16223	196	0.97
chr16_77291582_77292053	39.35	Gm31258	predicted gene, 31258	13743	0.19
chrX_58445733_58445903	38.89	Gm14645	predicted gene 14645	17743	0.26
chr13_29370907_29371310	38.80	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	103499	0.08
chr1_167182388_167182722	38.77	Gm37994	predicted gene, 37994	3833	0.21
chr4_70811006_70811333	38.66	Gm11227	predicted gene 11227	261504	0.02
chr7_36476904_36477159	38.65	Gm25247	predicted gene, 25247	46420	0.17
chr12_26886181_26886584	38.50	4933409F18Rik	RIKEN cDNA 4933409F18 gene	51509	0.18
chr18_74907209_74907702	38.34	Gm24559	predicted gene, 24559	1021	0.37
chr4_117379821_117380196	37.96	Rnf220	ring finger protein 220	4551	0.2
chr19_59866689_59867059	37.90	Gm17203	predicted gene 17203	34188	0.18
chr15_74194149_74194481	37.70	Gm15387	predicted gene 15387	99982	0.07
chr6_54552680_54553127	37.69	Scrn1	secernin 1	1543	0.37
chr12_84532163_84533007	37.59	Lin52	lin-52 homolog (C. elegans)	2541	0.25
chr13_52457883_52458068	37.52	Diras2	DIRAS family, GTP-binding RAS-like 2	73304	0.12
chr14_22037549_22037700	37.48	Gm7480	predicted gene 7480	1521	0.34
chr7_72601928_72602360	37.36	Gm37620	predicted gene, 37620	155	0.96
chr5_9339805_9340127	37.22	Gm15733	predicted gene 15733	13793	0.19
chr2_141913595_141913820	37.13	Fau-ps1	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 1	74918	0.13
chr10_67559869_67560062	37.12	4930563J15Rik	RIKEN cDNA 4930563J15 gene	10073	0.12
chr4_58670580_58670950	36.98	Gm12580	predicted gene 12580	12173	0.22
chr1_37097229_37097751	36.87	Vwa3b	von Willebrand factor A domain containing 3B	3041	0.26
chr3_47668909_47669138	36.71	Gm2229	predicted gene 2229	208685	0.03
chr3_3832009_3832194	36.67	Gm2071	predicted gene 2071	2817	0.34
chr7_111896291_111896806	36.66	Gm45588	predicted gene 45588	37993	0.17
chr6_107711195_107711474	36.46	4933431M02Rik	RIKEN cDNA 4933431M02 gene	83560	0.1
chr15_88468083_88468426	36.46	Zdhhc25	zinc finger, DHHC domain containing 25	132048	0.05
chr13_19668619_19668818	36.30	Gm47606	predicted gene, 47606	5216	0.18
chr2_63669718_63669895	36.27	Gm23503	predicted gene, 23503	237612	0.02
chr2_47834160_47834335	36.03	Gm25959	predicted gene, 25959	292263	0.01
chr7_63669022_63669353	36.00	Otud7a	OTU domain containing 7A	18372	0.2
chr5_5134656_5134845	35.96	Gm43623	predicted gene 43623	5357	0.21
chr13_83750227_83750397	35.77	C130071C03Rik	RIKEN cDNA C130071C03 gene	11449	0.12
chr17_49816718_49817010	35.76	Gm16555	predicted gene 16555	4961	0.27
chr6_17797574_17797931	35.62	Gm26738	predicted gene, 26738	37433	0.13
chr8_100516007_100516194	35.56	Gm45296	predicted gene 45296	77342	0.12
chr14_79880159_79880358	35.50	Gm6999	predicted gene 6999	10739	0.16
chr4_98578155_98578507	35.46	Gm22625	predicted gene, 22625	20466	0.18
chr13_78324889_78325040	35.46	Gm3963	predicted gene 3963	37880	0.11
chr3_35324266_35324460	35.29	Gm25442	predicted gene, 25442	1251	0.55
chr4_13480505_13480805	35.26	Gm11826	predicted gene 11826	2537	0.36
chr6_127701185_127701975	35.24	Gm43634	predicted gene 43634	57140	0.08
chr12_78987630_78988054	35.13	Tmem229b	transmembrane protein 229B	4364	0.21
chr6_137699415_137699798	35.08	Strap	serine/threonine kinase receptor associated protein	35472	0.16
chr17_66869624_66870037	35.02	Gm49940	predicted gene, 49940	7590	0.18
chr18_15544080_15544457	34.98	Aqp4	aquaporin 4	133286	0.05
chr12_48820304_48820469	34.98	AC124542.1	olfactory receptor 1400, pseudogene 1	85658	0.1
chr8_89135140_89135331	34.93	Gm6625	predicted gene 6625	11823	0.24
chr5_78622542_78622942	34.88	Gm43232	predicted gene 43232	82214	0.11
chr12_68217227_68217378	34.87	Gm47454	predicted gene, 47454	115320	0.06
chr11_26806852_26807151	34.84	Gm12070	predicted gene 12070	20368	0.19
chr6_138754677_138754895	34.81	Igbp1b	immunoglobulin (CD79A) binding protein 1b	96242	0.08
chr5_116895407_116895611	34.70	Gm43122	predicted gene 43122	64955	0.1
chr14_12338097_12338549	34.66	Gm24578	predicted gene, 24578	4419	0.14
chr6_40024235_40024578	34.51	Gm37995	predicted gene, 37995	2488	0.33
chr15_59973915_59974066	34.51	Gm7083	predicted gene 7083	3732	0.23
chr1_6752243_6752413	34.41	St18	suppression of tumorigenicity 18	14753	0.25
chr13_29565628_29566161	34.23	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	48440	0.19
chr17_16089277_16089512	34.21	Gm49778	predicted gene, 49778	73757	0.1
chr11_25696299_25696505	34.06	Gm23514	predicted gene, 23514	11262	0.27
chr4_126648482_126648847	34.02	Gm12933	predicted gene 12933	16590	0.13
chr4_24429061_24429567	34.01	Gm27243	predicted gene 27243	1576	0.43
chr2_82847422_82847589	33.78	Fsip2	fibrous sheath-interacting protein 2	96129	0.09
chr11_93488029_93488206	33.60	Gm24856	predicted gene, 24856	74793	0.12
chr10_29143863_29144732	33.57	Gm9996	predicted gene 9996	103	0.69
chr15_18818116_18818289	33.56	C030047K22Rik	RIKEN cDNA C030047K22 gene	572	0.56
chr4_28143160_28143344	33.52	Gm11911	predicted gene 11911	76075	0.11
chr7_79501638_79502069	33.51	Mir9-3hg	Mir9-3 host gene	1732	0.18
chr10_3920376_3921003	33.44	Gm23023	predicted gene, 23023	14188	0.15
chr1_46829988_46830169	33.33	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5821	0.22
chr8_61515184_61515647	33.30	Palld	palladin, cytoskeletal associated protein	485	0.84
chr4_39344820_39345025	33.28	Gm23607	predicted gene, 23607	49459	0.14
chr10_15249538_15249689	33.24	Gm18188	predicted gene, 18188	21565	0.23
chr2_28780313_28780498	33.24	Gm13385	predicted gene 13385	13164	0.13
chr18_17383276_17383802	33.23	4921533I20Rik	Riken cDNA 4921533I20 gene	63809	0.15
chr1_52470778_52471095	33.20	Nab1	Ngfi-A binding protein 1	3879	0.19
chr12_4523765_4524306	33.14	Gm31938	predicted gene, 31938	78	0.96
chr8_12126295_12126640	32.92	A230072I06Rik	RIKEN cDNA A230072I06 gene	152352	0.03
chr17_88764144_88764434	32.87	Lhcgr	luteinizing hormone/choriogonadotropin receptor	9767	0.24
chr5_78622272_78622464	32.86	Gm43232	predicted gene 43232	81840	0.11
chr13_101203160_101203326	32.85	5930438M14Rik	RIKEN cDNA 5930438M14 gene	28884	0.19
chr13_116087410_116087561	32.80	Gm47893	predicted gene, 47893	8550	0.28
chr3_27059899_27060315	32.78	Gm7558	predicted gene 7558	12154	0.17
chr15_95217343_95217494	32.77	1700129L04Rik	RIKEN cDNA 1700129L04 gene	55024	0.17
chr3_34561729_34562051	32.67	Sox2ot	SOX2 overlapping transcript (non-protein coding)	1498	0.34
chr14_103587274_103587565	32.67	Slain1	SLAIN motif family, member 1	62809	0.1
chr4_55929179_55929426	32.61	Gm12519	predicted gene 12519	64437	0.14
chr13_36518354_36518571	32.59	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	18635	0.16
chr14_68355462_68355920	32.54	Gm31227	predicted gene, 31227	105940	0.06
chr6_91324837_91325054	32.44	Wnt7a	wingless-type MMTV integration site family, member 7A	40126	0.12
chr18_50397132_50397306	32.41	Fam170a	family with sequence similarity 170, member A	118848	0.06
chr16_67610911_67611282	32.29	Cadm2	cell adhesion molecule 2	9397	0.25
chr14_35112923_35113111	32.23	Gm49034	predicted gene, 49034	106421	0.07
chr11_43270024_43270232	32.17	Gm12146	predicted gene 12146	10344	0.19
chr18_81831298_81831489	32.16	Gm30454	predicted gene, 30454	18623	0.19
chr19_41164805_41164972	32.14	Tll2	tolloid-like 2	41886	0.16
chr13_40606764_40607229	32.02	Gm47039	predicted gene, 47039	517	0.78
chr5_150894457_150894771	31.96	Gm43298	predicted gene 43298	11972	0.2
chr10_31551495_31551682	31.86	Gm47693	predicted gene, 47693	5852	0.19
chr17_63807674_63808197	31.84	Fer	fer (fms/fps related) protein kinase	55127	0.13
chr3_57919632_57919807	31.83	Gm24531	predicted gene, 24531	2468	0.24
chr3_34504632_34504783	31.77	Gm29135	predicted gene 29135	22500	0.16
chr7_142902999_142903346	31.76	Th	tyrosine hydroxylase	3158	0.22
chr4_54331384_54331565	31.68	Gm12469	predicted gene 12469	95598	0.08
chr6_12337029_12337231	31.66	Thsd7a	thrombospondin, type I, domain containing 7A	12437	0.3
chr12_25871193_25871842	31.59	Gm47733	predicted gene, 47733	364	0.91
chr19_56476541_56476761	31.56	Plekhs1	pleckstrin homology domain containing, family S member 1	2250	0.3
chr3_6183428_6183711	31.56	Gm6162	predicted gene 6162	15745	0.23
chr4_18046647_18046997	31.45	Mmp16	matrix metallopeptidase 16	4935	0.29
chr3_5347364_5347521	31.45	Zfhx4	zinc finger homeodomain 4	105770	0.07
chr13_84056571_84056869	31.42	Gm17750	predicted gene, 17750	8052	0.22
chr14_64233778_64233929	31.36	9630015K15Rik	RIKEN cDNA 9630015K15 gene	117539	0.05
chr12_29789878_29790063	31.35	Myt1l	myelin transcription factor 1-like	50240	0.17
chr2_50971381_50971555	31.29	Gm13498	predicted gene 13498	61784	0.14
chr18_46997978_46998292	31.26	Gm22791	predicted gene, 22791	12654	0.15
chr6_61042953_61043250	31.15	Gm43892	predicted gene, 43892	1892	0.33
chr2_106512677_106513062	31.07	Gm14015	predicted gene 14015	10234	0.26
chr4_148291962_148292123	31.03	Disp3	dispatched RND transporter family member 3	4077	0.19
chr6_61066614_61066949	31.02	Gm43893	predicted gene, 43893	2474	0.28
chr8_13454338_13454755	31.00	Tmem255b	transmembrane protein 255B	932	0.51
chr2_22620080_22620281	30.97	Gad2	glutamic acid decarboxylase 2	2025	0.23
chr17_62659448_62659775	30.91	Gm25800	predicted gene, 25800	202491	0.03
chr13_119753907_119754230	30.81	Nim1k	NIM1 serine/threonine protein kinase	1814	0.21
chr17_90704847_90705136	30.81	Nrxn1	neurexin I	4217	0.32
chr17_69686012_69686193	30.78	Gm49895	predicted gene, 49895	89910	0.08
chr1_138497460_138497658	30.78	Gm28501	predicted gene 28501	18056	0.2
chr18_8044886_8045210	30.75	Gm4833	predicted gene 4833	6155	0.28
chr12_102511368_102511747	30.73	Golga5	golgi autoantigen, golgin subfamily a, 5	27100	0.14
chr14_123065129_123065306	30.72	AA536875	expressed sequence AA536875	21935	0.22
chr12_65428316_65428602	30.71	Gm26015	predicted gene, 26015	22489	0.22
chr4_82915979_82916332	30.62	Frem1	Fras1 related extracellular matrix protein 1	1721	0.41
chr3_35332947_35333329	30.62	Gm25442	predicted gene, 25442	7524	0.26
chr11_112501711_112502406	30.61	BC006965	cDNA sequence BC006965	167340	0.04
chr8_36014873_36015024	30.58	Rps12-ps24	ribosomal protein S12, pseudogene 24	10805	0.2
chr10_16052455_16052829	30.57	C330004P14Rik	RIKEN cDNA C330004P14 gene	260865	0.02
chr13_29371351_29371690	30.57	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	103087	0.08
chr19_15668305_15668530	30.57	Gm24319	predicted gene, 24319	11587	0.3
chr7_96865260_96865776	30.51	Gm25712	predicted gene, 25712	2139	0.28
chr2_49719443_49719668	30.51	Kif5c	kinesin family member 5C	3012	0.3
chr3_110010549_110010756	30.50	Gm12535	predicted gene 12535	103268	0.07
chr13_8202686_8203175	30.43	Adarb2	adenosine deaminase, RNA-specific, B2	8	0.97
chr16_43603831_43604250	30.41	Mir568	microRNA 568	36615	0.15
chr13_13820325_13820514	30.36	Gng4	guanine nucleotide binding protein (G protein), gamma 4	1140	0.45
chr3_88205312_88205479	30.35	AI849053	expressed sequence AI849053	800	0.34
chr3_98990771_98991097	30.34	5730437C11Rik	RIKEN cDNA 5730437C11 gene	49678	0.1
chr18_21185734_21186067	30.25	Gm6378	predicted pseudogene 6378	108791	0.05
chr17_73477274_73477427	30.18	Gm49876	predicted gene, 49876	16901	0.16
chr8_40650752_40651179	30.10	Mtmr7	myotubularin related protein 7	16168	0.14
chr1_165935347_165935547	30.08	Pou2f1	POU domain, class 2, transcription factor 1	436	0.79
chr9_37625246_37625717	30.07	Siae	sialic acid acetylesterase	3827	0.14
chr7_125036708_125036896	30.07	Gm45093	predicted gene 45093	32689	0.19
chr13_78581171_78581365	30.06	Gm48402	predicted gene, 48402	56749	0.14
chr8_26677560_26678005	30.05	Gm32098	predicted gene, 32098	9476	0.18
chrX_166344291_166344543	30.05	Gpm6b	glycoprotein m6b	275	0.93
chr13_25751437_25751638	30.04	Gm11350	predicted gene 11350	70394	0.13
chr1_68142571_68142936	30.04	Gm37100	predicted gene, 37100	26206	0.23
chr4_22066929_22067080	30.02	Gm11880	predicted gene 11880	50528	0.14
chr8_12127510_12127825	30.00	A230072I06Rik	RIKEN cDNA A230072I06 gene	151152	0.03
chr16_63806441_63806811	29.92	Epha3	Eph receptor A3	56787	0.15
chr1_135645775_135646042	29.92	Nav1	neuron navigator 1	42197	0.12
chr11_80623114_80623380	29.91	C030013C21Rik	RIKEN cDNA C030013C21 gene	114141	0.05
chr11_71414747_71415135	29.85	Gm16013	predicted gene 16013	21239	0.21
chr12_44479679_44479987	29.79	Nrcam	neuronal cell adhesion molecule	23173	0.22
chr16_91140532_91140860	29.74	Gm49612	predicted gene, 49612	5220	0.12
chr10_17479308_17479459	29.68	Gm47768	predicted gene, 47768	35347	0.16
chr16_59854456_59854822	29.68	Epha6	Eph receptor A6	151082	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
42.9	128.6	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
16.8	50.3	GO:0060166	olfactory pit development(GO:0060166)
13.8	55.3	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
12.9	90.3	GO:0016198	axon choice point recognition(GO:0016198)
12.1	36.4	GO:0032289	central nervous system myelin formation(GO:0032289)
11.0	88.4	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
11.0	54.8	GO:0098596	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
10.6	42.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
9.6	38.6	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
9.6	28.9	GO:0043490	malate-aspartate shuttle(GO:0043490)
9.3	9.3	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
9.3	27.8	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
9.2	27.7	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
9.1	36.2	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
9.0	26.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
8.9	80.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
8.6	34.4	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
8.5	25.4	GO:0060178	regulation of exocyst localization(GO:0060178)
8.1	72.8	GO:0060013	righting reflex(GO:0060013)
8.1	24.2	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
7.8	23.5	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
7.7	85.1	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
7.3	21.9	GO:0046684	response to pyrethroid(GO:0046684)
7.0	14.1	GO:1903802	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
7.0	27.9	GO:0007258	JUN phosphorylation(GO:0007258)
6.9	13.9	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
6.9	48.3	GO:0045161	neuronal ion channel clustering(GO:0045161)
6.8	20.4	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
6.8	74.6	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
6.8	27.0	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
6.8	33.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
6.7	26.8	GO:0060594	mammary gland specification(GO:0060594)
6.7	20.1	GO:0009957	epidermal cell fate specification(GO:0009957)
6.6	19.9	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
6.6	26.4	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
6.3	12.6	GO:0046959	habituation(GO:0046959)
6.3	25.2	GO:0060486	Clara cell differentiation(GO:0060486)
6.2	43.3	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
6.1	18.4	GO:0007412	axon target recognition(GO:0007412)
6.1	49.0	GO:0035881	amacrine cell differentiation(GO:0035881)
6.1	30.6	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
6.1	12.2	GO:0071503	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
6.0	17.9	GO:0060221	retinal rod cell differentiation(GO:0060221)
5.9	23.7	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
5.8	35.0	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
5.8	17.4	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
5.8	11.6	GO:0021564	vagus nerve development(GO:0021564)
5.8	11.6	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
5.7	17.2	GO:0030070	insulin processing(GO:0030070)
5.6	11.3	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
5.6	22.3	GO:0060279	positive regulation of ovulation(GO:0060279)
5.5	33.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
5.5	11.1	GO:0048880	sensory system development(GO:0048880)
5.5	16.6	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
5.5	5.5	GO:0060174	limb bud formation(GO:0060174)
5.5	11.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
5.3	26.3	GO:0019532	oxalate transport(GO:0019532)
5.2	15.7	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
5.1	50.8	GO:0071803	positive regulation of podosome assembly(GO:0071803)
5.1	20.3	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
5.1	15.2	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
5.0	5.0	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
5.0	20.2	GO:0023041	neuronal signal transduction(GO:0023041)
5.0	24.8	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
4.9	19.8	GO:1903977	positive regulation of glial cell migration(GO:1903977)
4.8	14.4	GO:0001927	exocyst assembly(GO:0001927)
4.7	19.0	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
4.7	18.8	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
4.7	14.1	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
4.7	23.3	GO:1903887	motile primary cilium assembly(GO:1903887)
4.7	18.6	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
4.6	18.3	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
4.6	41.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
4.6	77.4	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
4.5	4.5	GO:0031223	auditory behavior(GO:0031223)
4.5	18.2	GO:0006538	glutamate catabolic process(GO:0006538)
4.5	9.0	GO:0003358	noradrenergic neuron development(GO:0003358)
4.5	22.5	GO:0021631	optic nerve morphogenesis(GO:0021631)
4.5	31.5	GO:0021871	forebrain regionalization(GO:0021871)
4.5	13.4	GO:0070634	transepithelial ammonium transport(GO:0070634)
4.5	13.4	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
4.5	17.8	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
4.4	8.9	GO:0051964	negative regulation of synapse assembly(GO:0051964)
4.4	8.8	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
4.4	8.8	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
4.4	13.2	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
4.3	4.3	GO:0014028	notochord formation(GO:0014028)
4.3	17.0	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
4.2	12.6	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
4.1	28.7	GO:0097105	presynaptic membrane assembly(GO:0097105)
4.1	12.2	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
4.0	8.1	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
4.0	12.1	GO:0072092	ureteric bud invasion(GO:0072092)
4.0	16.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
4.0	12.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
4.0	11.9	GO:0089700	protein kinase D signaling(GO:0089700)
3.9	11.7	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
3.9	15.5	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
3.8	7.6	GO:0061642	chemoattraction of axon(GO:0061642)
3.8	30.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
3.8	11.3	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
3.7	11.2	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
3.7	3.7	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
3.7	36.9	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
3.6	7.3	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
3.6	3.6	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
3.6	25.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
3.6	17.9	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
3.6	14.3	GO:0006166	purine ribonucleoside salvage(GO:0006166)
3.6	10.7	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
3.5	42.2	GO:0048268	clathrin coat assembly(GO:0048268)
3.5	14.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
3.4	13.7	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
3.4	6.8	GO:0051654	establishment of mitochondrion localization(GO:0051654)
3.3	13.3	GO:0035701	hematopoietic stem cell migration(GO:0035701)
3.3	3.3	GO:0014042	positive regulation of neuron maturation(GO:0014042)
3.3	13.2	GO:0003344	pericardium morphogenesis(GO:0003344)
3.3	6.6	GO:0043366	beta selection(GO:0043366)
3.3	3.3	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
3.3	9.9	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
3.3	13.0	GO:0090427	activation of meiosis(GO:0090427)
3.3	3.3	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
3.2	12.9	GO:0021559	trigeminal nerve development(GO:0021559)
3.2	6.4	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
3.2	6.4	GO:0021847	ventricular zone neuroblast division(GO:0021847)
3.2	9.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
3.2	12.8	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
3.2	16.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
3.2	9.5	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
3.1	25.1	GO:0046069	cGMP catabolic process(GO:0046069)
3.1	12.4	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
3.1	6.2	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
3.1	12.4	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
3.1	24.7	GO:0097120	receptor localization to synapse(GO:0097120)
3.1	6.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
3.1	9.2	GO:0048852	diencephalon morphogenesis(GO:0048852)
3.0	12.1	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
3.0	14.9	GO:0007256	activation of JNKK activity(GO:0007256)
2.9	231.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.9	2.9	GO:0021861	forebrain radial glial cell differentiation(GO:0021861)
2.9	8.8	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.9	5.8	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
2.9	14.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
2.9	14.4	GO:0048664	neuron fate determination(GO:0048664)
2.9	8.6	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
2.8	150.7	GO:0051965	positive regulation of synapse assembly(GO:0051965)
2.8	14.2	GO:0071625	vocalization behavior(GO:0071625)
2.8	39.7	GO:0016082	synaptic vesicle priming(GO:0016082)
2.8	11.3	GO:0035627	ceramide transport(GO:0035627)
2.8	62.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
2.8	8.4	GO:0060005	vestibular reflex(GO:0060005)
2.8	8.4	GO:1990034	calcium ion export from cell(GO:1990034)
2.8	11.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.8	13.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
2.8	5.5	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
2.8	8.3	GO:0003219	cardiac right ventricle formation(GO:0003219)
2.7	2.7	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
2.7	8.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
2.7	10.7	GO:0048341	paraxial mesoderm formation(GO:0048341)
2.6	13.2	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
2.6	5.2	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
2.5	7.6	GO:0060437	lung growth(GO:0060437)
2.5	5.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
2.5	15.2	GO:0035641	locomotory exploration behavior(GO:0035641)
2.5	2.5	GO:0072050	S-shaped body morphogenesis(GO:0072050)
2.5	5.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
2.5	7.5	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
2.5	17.4	GO:0060179	male mating behavior(GO:0060179)
2.5	10.0	GO:0060676	ureteric bud formation(GO:0060676)
2.5	7.5	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
2.5	29.8	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
2.5	14.8	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
2.4	7.3	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
2.4	21.6	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
2.4	2.4	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
2.4	7.1	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
2.3	13.9	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
2.3	18.4	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.3	6.9	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
2.3	6.9	GO:0001834	trophectodermal cell proliferation(GO:0001834)
2.3	11.3	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
2.3	2.3	GO:0006106	fumarate metabolic process(GO:0006106)
2.3	6.8	GO:0030035	microspike assembly(GO:0030035)
2.2	11.2	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
2.2	2.2	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
2.2	11.1	GO:0048681	negative regulation of axon regeneration(GO:0048681)
2.2	2.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
2.2	4.4	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
2.2	10.9	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
2.1	32.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
2.1	2.1	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
2.1	8.5	GO:0002051	osteoblast fate commitment(GO:0002051)
2.1	12.7	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
2.1	6.3	GO:0032474	otolith morphogenesis(GO:0032474)
2.1	6.2	GO:0071397	cellular response to cholesterol(GO:0071397)
2.1	14.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
2.1	32.8	GO:0008045	motor neuron axon guidance(GO:0008045)
2.0	4.1	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
2.0	16.1	GO:0002329	pre-B cell differentiation(GO:0002329)
2.0	4.0	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
2.0	18.0	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
2.0	8.0	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
2.0	7.9	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
2.0	2.0	GO:0042713	sperm ejaculation(GO:0042713)
2.0	4.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
2.0	2.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
1.9	1.9	GO:0006848	pyruvate transport(GO:0006848)
1.9	5.7	GO:2000680	regulation of rubidium ion transport(GO:2000680) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.9	3.8	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.9	1.9	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
1.9	9.5	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.9	7.6	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.9	1.9	GO:0098828	modulation of inhibitory postsynaptic potential(GO:0098828)
1.9	3.8	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.9	7.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.9	7.5	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
1.9	1.9	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.9	7.4	GO:0021979	hypothalamus cell differentiation(GO:0021979)
1.8	12.8	GO:0006450	regulation of translational fidelity(GO:0006450)
1.8	1.8	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.8	5.5	GO:0021544	subpallium development(GO:0021544)
1.8	10.9	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
1.8	3.6	GO:0000101	sulfur amino acid transport(GO:0000101)
1.8	7.2	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.8	3.6	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.8	1.8	GO:1900452	regulation of long term synaptic depression(GO:1900452)
1.8	21.4	GO:0016486	peptide hormone processing(GO:0016486)
1.7	8.7	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
1.7	10.4	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
1.7	5.1	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
1.7	18.8	GO:0001553	luteinization(GO:0001553)
1.7	1.7	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
1.7	6.8	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.7	3.4	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.7	3.4	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.7	20.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
1.7	6.7	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
1.7	6.7	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
1.7	1.7	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
1.6	3.3	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
1.6	3.3	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
1.6	6.5	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
1.6	3.3	GO:0070253	somatostatin secretion(GO:0070253)
1.6	4.8	GO:0014732	skeletal muscle atrophy(GO:0014732)
1.6	4.8	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
1.6	1.6	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.6	11.0	GO:0048149	behavioral response to ethanol(GO:0048149)
1.6	4.7	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.6	20.3	GO:0001964	startle response(GO:0001964)
1.6	4.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.5	4.6	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.5	4.6	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.5	1.5	GO:0097374	sensory neuron axon guidance(GO:0097374)
1.5	3.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
1.5	42.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.5	4.5	GO:0042126	nitrate metabolic process(GO:0042126)
1.5	1.5	GO:1902570	protein localization to nucleolus(GO:1902570)
1.5	1.5	GO:0060523	prostate epithelial cord elongation(GO:0060523)
1.5	13.3	GO:0071435	potassium ion export(GO:0071435)
1.5	5.9	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.5	5.9	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.5	8.8	GO:0099515	actin filament-based transport(GO:0099515)
1.4	2.9	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
1.4	4.3	GO:0006532	aspartate biosynthetic process(GO:0006532)
1.4	4.2	GO:0006553	lysine metabolic process(GO:0006553)
1.4	2.8	GO:2000821	regulation of grooming behavior(GO:2000821)
1.4	1.4	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
1.4	4.2	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
1.4	4.2	GO:0002930	trabecular meshwork development(GO:0002930)
1.4	4.2	GO:1901529	positive regulation of anion channel activity(GO:1901529)
1.4	2.8	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
1.4	5.6	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.4	4.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
1.4	5.5	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
1.4	5.5	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.4	5.4	GO:0006642	triglyceride mobilization(GO:0006642)
1.4	8.2	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
1.3	5.4	GO:0034239	regulation of macrophage fusion(GO:0034239)
1.3	5.4	GO:0042414	epinephrine metabolic process(GO:0042414)
1.3	4.0	GO:0006203	dGTP catabolic process(GO:0006203)
1.3	1.3	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.3	4.0	GO:0048840	otolith development(GO:0048840)
1.3	6.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.3	4.0	GO:1901525	negative regulation of macromitophagy(GO:1901525)
1.3	1.3	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.3	1.3	GO:0060278	regulation of ovulation(GO:0060278)
1.3	7.9	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.3	3.9	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.3	1.3	GO:1903935	negative regulation of cardiac muscle contraction(GO:0055118) response to sodium arsenite(GO:1903935)
1.3	6.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.3	2.6	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
1.3	5.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
1.3	6.5	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
1.3	2.6	GO:0019478	D-amino acid catabolic process(GO:0019478)
1.3	5.1	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.3	3.8	GO:0030432	peristalsis(GO:0030432)
1.2	6.2	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
1.2	6.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
1.2	1.2	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
1.2	3.7	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.2	3.7	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
1.2	2.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
1.2	1.2	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
1.2	3.6	GO:0060449	bud elongation involved in lung branching(GO:0060449)
1.2	9.6	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
1.2	6.0	GO:0015808	L-alanine transport(GO:0015808)
1.2	2.4	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
1.2	2.4	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
1.2	2.4	GO:0051665	membrane raft localization(GO:0051665)
1.2	1.2	GO:0050942	positive regulation of pigment cell differentiation(GO:0050942)
1.2	1.2	GO:0035754	B cell chemotaxis(GO:0035754)
1.2	3.5	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
1.1	3.4	GO:0007525	somatic muscle development(GO:0007525)
1.1	6.7	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
1.1	3.4	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
1.1	7.8	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
1.1	2.2	GO:2000774	positive regulation of cellular senescence(GO:2000774)
1.1	1.1	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
1.1	5.5	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
1.1	3.3	GO:0022038	corpus callosum development(GO:0022038)
1.1	3.3	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
1.1	2.2	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
1.1	3.2	GO:0010996	response to auditory stimulus(GO:0010996)
1.1	17.2	GO:0007616	long-term memory(GO:0007616)
1.1	7.5	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.1	9.7	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.1	3.2	GO:0097070	ductus arteriosus closure(GO:0097070)
1.1	1.1	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
1.1	2.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
1.1	2.1	GO:0008355	olfactory learning(GO:0008355)
1.1	3.2	GO:0030242	pexophagy(GO:0030242)
1.0	8.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
1.0	5.2	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.0	5.2	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.0	1.0	GO:0021554	optic nerve development(GO:0021554)
1.0	25.6	GO:0050771	negative regulation of axonogenesis(GO:0050771)
1.0	3.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
1.0	1.0	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.0	2.0	GO:0090148	membrane fission(GO:0090148)
1.0	13.1	GO:0060997	dendritic spine morphogenesis(GO:0060997)
1.0	12.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.0	2.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
1.0	3.0	GO:0031296	B cell costimulation(GO:0031296)
1.0	3.0	GO:0071316	cellular response to nicotine(GO:0071316)
1.0	3.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.0	9.0	GO:1990403	embryonic brain development(GO:1990403)
1.0	3.0	GO:0035262	gonad morphogenesis(GO:0035262)
1.0	3.0	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
1.0	5.0	GO:0050957	equilibrioception(GO:0050957)
1.0	4.9	GO:0001504	neurotransmitter uptake(GO:0001504)
1.0	8.9	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
1.0	2.9	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
1.0	4.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.0	1.0	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
1.0	2.9	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.0	6.8	GO:0019673	GDP-mannose metabolic process(GO:0019673)
1.0	1.9	GO:0072318	clathrin coat disassembly(GO:0072318)
0.9	2.8	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.9	5.7	GO:0003338	metanephros morphogenesis(GO:0003338)
0.9	3.7	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.9	3.7	GO:0042473	outer ear morphogenesis(GO:0042473)
0.9	0.9	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.9	13.5	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9	3.6	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.9	5.4	GO:0006108	malate metabolic process(GO:0006108)
0.9	1.8	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.9	1.8	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.9	2.7	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.9	5.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.9	2.7	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.9	0.9	GO:0035106	operant conditioning(GO:0035106)
0.9	1.8	GO:0046098	guanine metabolic process(GO:0046098)
0.9	3.5	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.9	4.4	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.9	2.6	GO:0060468	prevention of polyspermy(GO:0060468)
0.9	0.9	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.9	1.7	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.9	7.7	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.9	3.4	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.8	1.7	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.8	0.8	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.8	2.5	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.8	0.8	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.8	7.5	GO:0080111	DNA demethylation(GO:0080111)
0.8	5.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.8	4.9	GO:0003356	regulation of cilium beat frequency(GO:0003356)
0.8	4.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8	3.2	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.8	2.4	GO:0007638	mechanosensory behavior(GO:0007638)
0.8	2.4	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.8	1.6	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.8	0.8	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.8	1.6	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.8	3.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.8	14.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.8	17.8	GO:0003407	neural retina development(GO:0003407)
0.8	1.5	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.8	3.1	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.8	6.1	GO:1990118	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.8	6.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.8	2.3	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.8	2.3	GO:0060004	reflex(GO:0060004)
0.8	1.5	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.8	3.0	GO:0070365	hepatocyte differentiation(GO:0070365)
0.7	2.2	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.7	0.7	GO:0097212	lysosomal membrane organization(GO:0097212)
0.7	2.2	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.7	3.7	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.7	2.9	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.7	3.7	GO:0060736	prostate gland growth(GO:0060736)
0.7	3.7	GO:0080009	mRNA methylation(GO:0080009)
0.7	2.9	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.7	2.9	GO:0070314	G1 to G0 transition(GO:0070314)
0.7	1.5	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.7	4.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.7	9.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.7	9.3	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.7	1.4	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.7	4.2	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
0.7	0.7	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.7	0.7	GO:0061196	fungiform papilla development(GO:0061196)
0.7	2.8	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.7	0.7	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.7	6.2	GO:0035428	hexose transmembrane transport(GO:0035428)
0.7	14.5	GO:0019228	neuronal action potential(GO:0019228)
0.7	1.4	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.7	0.7	GO:2000969	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.7	6.8	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.7	2.7	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.7	4.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.7	6.1	GO:0046851	negative regulation of bone remodeling(GO:0046851)
0.7	3.4	GO:0045760	positive regulation of action potential(GO:0045760)
0.7	2.0	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.7	0.7	GO:0035766	cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.7	4.0	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.7	4.0	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.7	0.7	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.7	5.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.7	13.9	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.7	2.0	GO:0043382	regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
0.7	2.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.7	9.9	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.7	2.0	GO:1902267	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.7	5.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.7	2.6	GO:0046113	nucleobase catabolic process(GO:0046113)
0.6	1.9	GO:0043615	astrocyte cell migration(GO:0043615)
0.6	0.6	GO:0090494	catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.6	1.9	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.6	2.6	GO:0030091	protein repair(GO:0030091)
0.6	1.9	GO:0034214	protein hexamerization(GO:0034214)
0.6	0.6	GO:0061439	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.6	1.9	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.6	1.3	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.6	3.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.6	3.1	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.6	0.6	GO:0090135	actin filament branching(GO:0090135)
0.6	0.6	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.6	4.8	GO:0006983	ER overload response(GO:0006983)
0.6	4.8	GO:0042989	sequestering of actin monomers(GO:0042989)
0.6	1.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.6	11.4	GO:0035315	hair cell differentiation(GO:0035315)
0.6	1.8	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.6	3.6	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.6	1.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.6	2.4	GO:0021854	hypothalamus development(GO:0021854)
0.6	2.3	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.6	4.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.6	0.6	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.6	1.7	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.6	4.6	GO:0048266	behavioral response to pain(GO:0048266)
0.6	1.7	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.6	0.6	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.5	2.2	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.5	1.6	GO:0046952	ketone body catabolic process(GO:0046952)
0.5	1.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.5	2.7	GO:0001778	plasma membrane repair(GO:0001778)
0.5	5.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.5	5.8	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.5	1.6	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.5	0.5	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.5	1.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.5	1.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.5	0.5	GO:2000449	regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.5	1.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.5	1.0	GO:0042940	D-amino acid transport(GO:0042940)
0.5	13.6	GO:0034605	cellular response to heat(GO:0034605)
0.5	1.5	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.5	1.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.5	1.0	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.5	1.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.5	2.9	GO:0048733	sebaceous gland development(GO:0048733)
0.5	1.9	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.5	0.5	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.5	0.9	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.5	7.1	GO:0008347	glial cell migration(GO:0008347)
0.5	1.4	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.5	1.9	GO:0001975	response to amphetamine(GO:0001975)
0.5	3.7	GO:1903405	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.5	0.5	GO:0010966	regulation of phosphate transport(GO:0010966)
0.5	0.9	GO:0060467	negative regulation of fertilization(GO:0060467)
0.5	0.9	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.5	0.9	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.5	0.9	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.5	1.4	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5	0.5	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.4	1.8	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.4	4.0	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4	0.4	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.4	2.2	GO:0009235	cobalamin metabolic process(GO:0009235)
0.4	2.6	GO:0015884	folic acid transport(GO:0015884)
0.4	0.9	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.4	4.3	GO:0090169	regulation of spindle assembly(GO:0090169)
0.4	1.7	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4	3.4	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.4	0.8	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
0.4	0.4	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.4	3.3	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.4	4.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.4	1.7	GO:2000399	negative regulation of thymocyte aggregation(GO:2000399)
0.4	1.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.4	0.4	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.4	6.2	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.4	1.2	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.4	0.8	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.4	6.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.4	0.8	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.4	0.8	GO:1900368	regulation of RNA interference(GO:1900368)
0.4	2.4	GO:0042428	serotonin metabolic process(GO:0042428)
0.4	0.4	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.4	3.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.4	0.8	GO:2000850	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.4	1.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.4	0.4	GO:1902667	regulation of axon guidance(GO:1902667)
0.4	1.2	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4	2.3	GO:0043576	regulation of respiratory gaseous exchange(GO:0043576)
0.4	1.5	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.4	0.8	GO:0070268	cornification(GO:0070268)
0.4	18.9	GO:0007411	axon guidance(GO:0007411)
0.4	2.6	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4	2.2	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.4	1.5	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4	0.7	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.4	0.4	GO:0090237	regulation of arachidonic acid secretion(GO:0090237)
0.4	0.7	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.4	0.4	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.4	1.1	GO:2000551	regulation of T-helper 2 cell cytokine production(GO:2000551)
0.4	1.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.3	1.7	GO:1901341	positive regulation of store-operated calcium channel activity(GO:1901341)
0.3	0.3	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.3	0.7	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.3	0.7	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.3	0.6	GO:0042640	anagen(GO:0042640)
0.3	2.9	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.3	2.8	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3	0.6	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3	0.3	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.3	1.2	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.3	0.9	GO:0048014	Tie signaling pathway(GO:0048014)
0.3	0.9	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.3	0.3	GO:0051795	regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.3	0.9	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.3	0.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.3	0.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.3	1.7	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.3	0.3	GO:0050975	sensory perception of touch(GO:0050975)
0.3	6.6	GO:0006270	DNA replication initiation(GO:0006270)
0.3	1.4	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3	0.3	GO:0071639	positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.3	1.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.3	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3	1.1	GO:0070472	uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472)
0.3	0.3	GO:0006533	aspartate catabolic process(GO:0006533)
0.3	0.5	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.3	0.3	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.3	1.5	GO:0042474	middle ear morphogenesis(GO:0042474)
0.3	0.8	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3	6.3	GO:0031424	keratinization(GO:0031424)
0.3	0.3	GO:1904833	regulation of superoxide dismutase activity(GO:1901668) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.2	0.2	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.2	7.3	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.2	0.5	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.2	0.9	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2	0.7	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2	0.5	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2	0.2	GO:0086011	membrane repolarization during action potential(GO:0086011)
0.2	0.5	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2	0.7	GO:0036093	germ cell proliferation(GO:0036093)
0.2	2.3	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	0.9	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.2	0.7	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.2	0.7	GO:0048239	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2	1.1	GO:0090383	phagosome acidification(GO:0090383)
0.2	0.4	GO:0015755	fructose transport(GO:0015755)
0.2	0.2	GO:0009217	purine deoxyribonucleoside triphosphate catabolic process(GO:0009217)
0.2	0.9	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.2	0.2	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2	0.4	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.2	0.4	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.2	2.9	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.2	0.2	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.2	0.8	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.2	0.4	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2	0.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.2	0.8	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2	0.2	GO:0097485	neuron projection guidance(GO:0097485)
0.2	0.6	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.2	0.6	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2	1.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.2	0.6	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.2	0.2	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
0.2	1.7	GO:0006228	UTP biosynthetic process(GO:0006228)
0.2	0.8	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.2	0.6	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.2	0.7	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.2	3.0	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2	0.7	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.2	0.5	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.2	0.4	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.2	1.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	3.0	GO:0016601	Rac protein signal transduction(GO:0016601)
0.2	0.3	GO:0009826	unidimensional cell growth(GO:0009826)
0.2	0.7	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	0.7	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	1.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	0.5	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.2	0.8	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.3	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.2	1.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.2	0.3	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.2	0.5	GO:0097384	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2	0.5	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.9	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.1	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.1	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	1.6	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	0.3	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.8	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.4	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	0.4	GO:0002551	mast cell chemotaxis(GO:0002551)
0.1	0.8	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1	0.1	GO:0061055	myotome development(GO:0061055)
0.1	0.5	GO:0048478	replication fork protection(GO:0048478)
0.1	0.3	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.1	GO:1903431	positive regulation of cell maturation(GO:1903431)
0.1	0.3	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	1.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.1	0.1	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.1	0.7	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.7	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.1	0.7	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.3	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.1	0.1	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.7	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1	0.1	GO:0035826	rubidium ion transport(GO:0035826)
0.1	0.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	0.3	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.1	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.1	0.1	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
0.1	0.1	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.1	0.2	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.1	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.1	0.1	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.1	0.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1	0.1	GO:0038001	paracrine signaling(GO:0038001)
0.1	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.1	0.6	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.1	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.0	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.0	1.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.2	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.0	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.2	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0002407	dendritic cell chemotaxis(GO:0002407)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0009233	menaquinone metabolic process(GO:0009233)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.0	GO:0032303	regulation of icosanoid secretion(GO:0032303)
0.0	0.0	GO:0060926	cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.0	0.0	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.0	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.9	53.8	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
9.7	96.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
8.2	49.3	GO:0016012	sarcoglycan complex(GO:0016012)
7.7	53.8	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
7.6	22.9	GO:0072534	perineuronal net(GO:0072534)
5.8	29.2	GO:0044294	dendritic growth cone(GO:0044294)
5.7	68.4	GO:0043194	axon initial segment(GO:0043194)
5.7	90.8	GO:0048786	presynaptic active zone(GO:0048786)
5.6	28.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
5.3	127.9	GO:0044295	axonal growth cone(GO:0044295)
5.3	26.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
5.2	36.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
4.8	4.8	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
4.8	24.0	GO:0097433	dense body(GO:0097433)
4.4	220.1	GO:0042734	presynaptic membrane(GO:0042734)
4.4	26.1	GO:0032584	growth cone membrane(GO:0032584)
4.3	34.7	GO:0042788	polysomal ribosome(GO:0042788)
4.3	17.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
4.2	41.7	GO:0030673	axolemma(GO:0030673)
4.0	7.9	GO:0097418	neurofibrillary tangle(GO:0097418)
3.9	11.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
3.9	54.9	GO:0043196	varicosity(GO:0043196)
3.6	43.7	GO:0032426	stereocilium tip(GO:0032426)
3.4	30.6	GO:0035253	ciliary rootlet(GO:0035253)
3.2	9.5	GO:0033010	paranodal junction(GO:0033010)
3.2	41.2	GO:0031045	dense core granule(GO:0031045)
3.2	34.7	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
3.0	11.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.9	48.7	GO:0005614	interstitial matrix(GO:0005614)
2.8	5.6	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
2.7	8.2	GO:0048179	activin receptor complex(GO:0048179)
2.6	10.5	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.6	20.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
2.5	17.8	GO:0071437	invadopodium(GO:0071437)
2.5	9.9	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.3	6.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
2.2	6.7	GO:0005594	collagen type IX trimer(GO:0005594)
2.2	32.9	GO:0031527	filopodium membrane(GO:0031527)
2.1	10.5	GO:1990075	periciliary membrane compartment(GO:1990075)
2.0	2.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
2.0	20.0	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
2.0	5.9	GO:0097441	basilar dendrite(GO:0097441)
2.0	5.9	GO:0032280	symmetric synapse(GO:0032280)
2.0	2.0	GO:0005593	FACIT collagen trimer(GO:0005593)
1.9	5.8	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.8	16.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.8	1.8	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.8	7.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.8	37.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.7	11.8	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
1.7	5.1	GO:0000322	storage vacuole(GO:0000322)
1.7	3.3	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
1.6	11.4	GO:0043083	synaptic cleft(GO:0043083)
1.6	6.5	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.6	92.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
1.6	25.2	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.6	4.7	GO:0044326	dendritic spine neck(GO:0044326)
1.5	7.7	GO:0005672	transcription factor TFIIA complex(GO:0005672)
1.5	13.6	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.5	6.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
1.5	33.1	GO:0043198	dendritic shaft(GO:0043198)
1.5	6.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.5	6.0	GO:1990716	axonemal central apparatus(GO:1990716)
1.5	8.8	GO:0033270	paranode region of axon(GO:0033270)
1.5	16.1	GO:0030061	mitochondrial crista(GO:0030061)
1.4	130.8	GO:0045211	postsynaptic membrane(GO:0045211)
1.4	8.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
1.3	10.2	GO:0030991	intraciliary transport particle A(GO:0030991)
1.2	194.7	GO:0060076	excitatory synapse(GO:0060076)
1.2	16.9	GO:0043205	fibril(GO:0043205)
1.2	3.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.1	3.4	GO:0005608	laminin-3 complex(GO:0005608)
1.1	19.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
1.1	6.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1	4.2	GO:0019815	B cell receptor complex(GO:0019815)
1.0	11.3	GO:0042555	MCM complex(GO:0042555)
1.0	3.8	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.9	11.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.9	11.4	GO:0097546	ciliary base(GO:0097546)
0.9	4.4	GO:0061617	MICOS complex(GO:0061617)
0.9	20.5	GO:0032420	stereocilium(GO:0032420)
0.8	4.2	GO:0071547	piP-body(GO:0071547)
0.8	5.0	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.8	2.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.8	46.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8	5.4	GO:0033263	CORVET complex(GO:0033263)
0.7	6.6	GO:0036156	inner dynein arm(GO:0036156)
0.7	4.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.7	2.1	GO:0070939	Dsl1p complex(GO:0070939)
0.7	52.8	GO:0030426	growth cone(GO:0030426)
0.7	4.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.7	2.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.7	4.0	GO:0001674	female germ cell nucleus(GO:0001674)
0.7	8.0	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.6	14.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.6	29.8	GO:0043195	terminal bouton(GO:0043195)
0.6	9.9	GO:0042101	T cell receptor complex(GO:0042101)
0.6	13.0	GO:0098794	postsynapse(GO:0098794)
0.6	4.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6	0.6	GO:0044299	C-fiber(GO:0044299)
0.6	0.6	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.5	1.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	2.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.5	4.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.5	6.9	GO:0032809	neuronal cell body membrane(GO:0032809)
0.5	4.8	GO:0031512	motile primary cilium(GO:0031512)
0.5	4.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.5	5.6	GO:0046930	pore complex(GO:0046930)
0.4	59.3	GO:0031225	anchored component of membrane(GO:0031225)
0.4	0.4	GO:0033268	node of Ranvier(GO:0033268)
0.4	1.2	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.4	1.6	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.4	0.8	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4	1.2	GO:0043511	inhibin complex(GO:0043511)
0.4	1.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.4	0.4	GO:0035838	growing cell tip(GO:0035838)
0.4	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.4	2.8	GO:0044447	axoneme part(GO:0044447)
0.4	1.1	GO:0000802	transverse filament(GO:0000802)
0.4	8.1	GO:0034451	centriolar satellite(GO:0034451)
0.3	5.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.3	1.3	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.3	1.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.3	0.6	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3	5.4	GO:0031594	neuromuscular junction(GO:0031594)
0.3	1.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.3	1.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.3	1.4	GO:0045098	type III intermediate filament(GO:0045098)
0.3	0.8	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.3	0.8	GO:0043293	apoptosome(GO:0043293)
0.2	4.9	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.2	12.1	GO:0001533	cornified envelope(GO:0001533)
0.2	1.0	GO:1990246	uniplex complex(GO:1990246)
0.2	0.5	GO:1990923	PET complex(GO:1990923)
0.2	0.9	GO:0070876	SOSS complex(GO:0070876)
0.2	5.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	1.3	GO:0070847	core mediator complex(GO:0070847)
0.2	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.2	1.4	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	1.6	GO:0000137	Golgi cis cisterna(GO:0000137)
0.2	0.8	GO:0071546	pi-body(GO:0071546)
0.2	11.6	GO:0070382	exocytic vesicle(GO:0070382)
0.2	0.9	GO:0000796	condensin complex(GO:0000796)
0.2	0.5	GO:0071797	LUBAC complex(GO:0071797)
0.2	0.5	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.2	2.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	21.5	GO:0030424	axon(GO:0030424)
0.1	0.4	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	0.8	GO:0097440	apical dendrite(GO:0097440)
0.1	0.9	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	1.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	3.6	GO:0005871	kinesin complex(GO:0005871)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	2.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.1	3.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.4	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.8	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.5	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0019814	immunoglobulin complex(GO:0019814)
0.0	0.1	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0005687	U4 snRNP(GO:0005687)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
37.1	111.2	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
24.4	73.3	GO:0097109	neuroligin family protein binding(GO:0097109)
13.8	41.5	GO:0070699	type II activin receptor binding(GO:0070699)
13.6	68.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
13.1	52.5	GO:0035727	lysophosphatidic acid binding(GO:0035727)
12.5	37.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
9.6	38.3	GO:0032051	clathrin light chain binding(GO:0032051)
8.3	41.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
8.3	41.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
8.2	24.6	GO:0004351	glutamate decarboxylase activity(GO:0004351)
8.1	24.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
7.7	23.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
7.2	21.5	GO:0097108	hedgehog family protein binding(GO:0097108)
6.8	27.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
6.7	46.7	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
6.4	25.8	GO:0008502	melatonin receptor activity(GO:0008502)
6.4	19.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
6.2	12.5	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
5.9	17.6	GO:0008503	benzodiazepine receptor activity(GO:0008503)
5.8	17.4	GO:0050816	phosphothreonine binding(GO:0050816)
5.8	17.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
5.7	51.5	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
5.3	16.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
5.2	10.4	GO:0045503	dynein light chain binding(GO:0045503)
4.8	28.7	GO:0004385	guanylate kinase activity(GO:0004385)
4.7	28.3	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
4.5	27.1	GO:0008046	axon guidance receptor activity(GO:0008046)
4.5	40.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
4.1	37.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
4.0	16.1	GO:0005042	netrin receptor activity(GO:0005042)
3.8	3.8	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
3.8	22.5	GO:0034190	apolipoprotein receptor binding(GO:0034190)
3.7	22.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.6	79.5	GO:0071837	HMG box domain binding(GO:0071837)
3.6	10.8	GO:0016882	cyclo-ligase activity(GO:0016882)
3.5	31.7	GO:0038191	neuropilin binding(GO:0038191)
3.5	17.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.5	20.9	GO:0048495	Roundabout binding(GO:0048495)
3.5	10.4	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
3.4	10.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
3.3	39.7	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
3.3	3.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
3.3	13.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
3.3	9.8	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.2	6.3	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
3.1	9.3	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
3.1	9.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
3.1	12.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
3.1	12.2	GO:0070878	primary miRNA binding(GO:0070878)
2.9	20.4	GO:0043495	protein anchor(GO:0043495)
2.9	11.4	GO:0008179	adenylate cyclase binding(GO:0008179)
2.8	14.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.7	8.1	GO:0016015	morphogen activity(GO:0016015)
2.7	8.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
2.6	31.5	GO:0004000	adenosine deaminase activity(GO:0004000)
2.6	5.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
2.5	17.8	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
2.5	7.5	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.5	32.0	GO:0050811	GABA receptor binding(GO:0050811)
2.4	14.3	GO:0016421	CoA carboxylase activity(GO:0016421)
2.4	9.5	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.4	47.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
2.4	35.6	GO:0045499	chemorepellent activity(GO:0045499)
2.3	16.3	GO:0002151	G-quadruplex RNA binding(GO:0002151)
2.3	7.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
2.3	25.4	GO:0017065	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
2.3	46.1	GO:0017075	syntaxin-1 binding(GO:0017075)
2.3	13.5	GO:0032027	myosin light chain binding(GO:0032027)
2.2	6.6	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
2.2	8.8	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.2	8.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.2	8.7	GO:0004065	arylsulfatase activity(GO:0004065)
2.2	4.4	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.2	4.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
2.2	8.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.1	49.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
2.1	23.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.1	8.5	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
2.1	6.3	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
2.0	10.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
2.0	6.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
2.0	8.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
2.0	8.1	GO:0097001	ceramide binding(GO:0097001)
2.0	6.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
2.0	6.0	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
2.0	12.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
2.0	10.0	GO:0042609	CD4 receptor binding(GO:0042609)
2.0	6.0	GO:0005148	prolactin receptor binding(GO:0005148)
2.0	10.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
1.9	9.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
1.9	11.4	GO:0015198	oligopeptide transporter activity(GO:0015198)
1.8	16.6	GO:0004383	guanylate cyclase activity(GO:0004383)
1.8	7.3	GO:0033142	progesterone receptor binding(GO:0033142)
1.8	27.4	GO:0016805	dipeptidase activity(GO:0016805)
1.8	3.6	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
1.8	19.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
1.7	8.7	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.7	34.8	GO:0003785	actin monomer binding(GO:0003785)
1.7	7.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.7	6.9	GO:0051434	BH3 domain binding(GO:0051434)
1.7	3.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
1.7	8.6	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
1.7	36.9	GO:0005540	hyaluronic acid binding(GO:0005540)
1.6	4.8	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.6	4.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.6	4.7	GO:0035939	microsatellite binding(GO:0035939)
1.5	20.9	GO:0045295	gamma-catenin binding(GO:0045295)
1.5	3.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
1.5	5.9	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.4	8.5	GO:0001849	complement component C1q binding(GO:0001849)
1.4	5.6	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
1.4	6.9	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.3	4.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
1.3	17.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.3	33.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.3	13.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
1.3	3.9	GO:0017002	activin-activated receptor activity(GO:0017002)
1.3	1.3	GO:0048408	epidermal growth factor binding(GO:0048408)
1.3	6.4	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
1.3	5.2	GO:0034056	estrogen response element binding(GO:0034056)
1.3	3.9	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
1.3	17.6	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.2	6.2	GO:0004565	beta-galactosidase activity(GO:0004565)
1.2	9.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.2	1.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
1.2	4.8	GO:1904288	BAT3 complex binding(GO:1904288)
1.2	21.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
1.2	4.7	GO:0000403	Y-form DNA binding(GO:0000403)
1.1	2.3	GO:0004359	glutaminase activity(GO:0004359)
1.1	6.9	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
1.1	3.4	GO:0030151	molybdenum ion binding(GO:0030151)
1.1	4.5	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.1	10.0	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
1.1	15.4	GO:0004890	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
1.1	3.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
1.1	3.3	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.1	3.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
1.1	4.3	GO:0004127	cytidylate kinase activity(GO:0004127)
1.1	11.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
1.1	13.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0	2.1	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
1.0	2.0	GO:0097016	L27 domain binding(GO:0097016)
1.0	27.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.0	27.9	GO:0005272	sodium channel activity(GO:0005272)
1.0	4.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
1.0	10.0	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
1.0	5.9	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.0	6.7	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9	2.8	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.9	3.7	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.9	2.7	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.9	2.7	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.9	30.6	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.9	17.4	GO:0030332	cyclin binding(GO:0030332)
0.9	10.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.9	6.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.9	1.7	GO:0051425	PTB domain binding(GO:0051425)
0.8	2.5	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.8	1.7	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.8	17.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.8	1.6	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.8	0.8	GO:0016937	short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.8	2.4	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.8	4.8	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.8	3.9	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.8	16.3	GO:0042056	chemoattractant activity(GO:0042056)
0.8	5.4	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.8	2.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.7	8.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.7	2.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7	1.5	GO:0098821	BMP receptor activity(GO:0098821)
0.7	29.0	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.7	6.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7	7.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.7	4.3	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.7	9.1	GO:0015026	coreceptor activity(GO:0015026)
0.7	60.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.7	0.7	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.7	2.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.7	2.8	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.7	2.8	GO:0034584	piRNA binding(GO:0034584)
0.7	2.0	GO:0070052	collagen V binding(GO:0070052)
0.7	4.0	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.7	2.7	GO:1990932	5.8S rRNA binding(GO:1990932)
0.7	9.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.7	2.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.7	2.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.7	23.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.7	19.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.6	2.6	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.6	1.9	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.6	1.9	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6	1.9	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.6	3.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.6	0.6	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	1.8	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.6	1.8	GO:0032190	acrosin binding(GO:0032190)
0.6	1.7	GO:0031708	endothelin B receptor binding(GO:0031708)
0.6	0.6	GO:0004952	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.6	6.7	GO:0030955	potassium ion binding(GO:0030955)
0.6	7.8	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.6	1.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.6	11.6	GO:0005537	mannose binding(GO:0005537)
0.5	15.9	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	1.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.5	1.6	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.5	3.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.5	10.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5	9.7	GO:0031489	myosin V binding(GO:0031489)
0.5	3.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5	2.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5	3.0	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.5	2.0	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.5	2.5	GO:0071723	lipopeptide binding(GO:0071723)
0.5	2.0	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.5	1.0	GO:0043426	MRF binding(GO:0043426)
0.5	4.4	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.5	2.9	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.5	5.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5	2.8	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.5	5.6	GO:0031005	filamin binding(GO:0031005)
0.5	0.9	GO:0004969	histamine receptor activity(GO:0004969)
0.5	1.4	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.5	1.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5	1.8	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.4	2.2	GO:0045545	syndecan binding(GO:0045545)
0.4	2.6	GO:0008517	folic acid transporter activity(GO:0008517)
0.4	12.6	GO:0070888	E-box binding(GO:0070888)
0.4	8.2	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.4	4.2	GO:0000146	microfilament motor activity(GO:0000146)
0.4	1.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.4	0.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.4	1.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4	1.6	GO:0043842	Kdo transferase activity(GO:0043842)
0.4	1.2	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.4	0.4	GO:0008158	hedgehog receptor activity(GO:0008158)
0.4	1.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.4	4.2	GO:0051787	misfolded protein binding(GO:0051787)
0.4	2.7	GO:0030553	cGMP binding(GO:0030553)
0.4	0.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.4	1.5	GO:0004370	glycerol kinase activity(GO:0004370)
0.4	2.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3	5.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3	1.7	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	3.7	GO:0004697	protein kinase C activity(GO:0004697)
0.3	1.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.3	1.0	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.3	2.0	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3	0.3	GO:0055100	adiponectin binding(GO:0055100)
0.3	17.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3	1.2	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.3	3.1	GO:0022821	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.3	4.0	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3	3.4	GO:0005522	profilin binding(GO:0005522)
0.3	0.3	GO:0051378	serotonin binding(GO:0051378)
0.3	1.2	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.3	0.9	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3	0.6	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3	2.4	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3	1.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.3	0.8	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	1.2	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.2	5.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	5.8	GO:0017091	AU-rich element binding(GO:0017091)
0.2	1.4	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.2	3.0	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.2	5.0	GO:0015459	potassium channel regulator activity(GO:0015459)
0.2	0.9	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2	0.6	GO:0005502	11-cis retinal binding(GO:0005502)
0.2	1.0	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.2	3.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	0.9	GO:0002054	nucleobase binding(GO:0002054)
0.2	0.6	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.2	0.7	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.2	0.2	GO:0035240	dopamine binding(GO:0035240)
0.2	0.5	GO:0004946	bombesin receptor activity(GO:0004946)
0.2	0.5	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.2	0.3	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2	5.4	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	1.3	GO:0009881	photoreceptor activity(GO:0009881)
0.2	0.3	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.2	0.3	GO:0022835	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.2	2.7	GO:0005112	Notch binding(GO:0005112)
0.2	5.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.2	1.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.6	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.4	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.6	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	1.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.3	GO:0035870	dITP diphosphatase activity(GO:0035870)
0.1	1.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	1.9	GO:0005402	cation:sugar symporter activity(GO:0005402)
0.1	1.2	GO:0070990	snRNP binding(GO:0070990)
0.1	0.2	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	0.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.3	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.8	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.4	GO:0035325	Toll-like receptor binding(GO:0035325)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.3	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.1	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.1	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	1.8	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	1.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	1.2	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.1	0.4	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.1	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
0.1	0.5	GO:0001972	retinoic acid binding(GO:0001972)
0.1	1.4	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.2	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.4	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:1990190	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	2.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	5.2	GO:0005549	odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	157.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
3.2	9.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
3.1	3.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
2.2	41.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
1.9	5.8	ST G ALPHA I PATHWAY	G alpha i Pathway
1.6	3.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.4	37.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.3	14.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.3	15.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.0	27.2	ST ADRENERGIC	Adrenergic Pathway
1.0	13.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.9	2.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.9	24.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.9	24.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.9	2.6	PID INSULIN PATHWAY	Insulin Pathway
0.8	0.8	PID REELIN PATHWAY	Reelin signaling pathway
0.8	6.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.8	6.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.7	8.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.7	2.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.7	0.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.6	1.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6	2.5	PID IL2 1PATHWAY	IL2-mediated signaling events
0.5	5.8	PID ALK2 PATHWAY	ALK2 signaling events
0.5	9.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.5	16.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	13.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.5	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.5	4.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.4	1.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	52.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4	7.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.4	10.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	1.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.3	2.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	9.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	4.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	46.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	9.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	19.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.6	36.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
4.6	118.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
3.5	58.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
3.4	104.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
3.1	34.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
3.1	21.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
3.1	37.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
3.0	54.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
2.8	5.5	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
2.6	36.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.6	21.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
2.6	39.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.6	17.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
2.5	32.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
2.5	27.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
2.5	54.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.4	28.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
2.3	2.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.3	9.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
2.0	24.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
2.0	38.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
2.0	86.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
2.0	8.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
2.0	31.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
1.7	5.2	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
1.7	5.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.6	6.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
1.6	25.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.6	3.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
1.5	15.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.5	13.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
1.4	53.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.3	21.0	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
1.3	24.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
1.3	10.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.2	21.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
1.1	13.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.1	1.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
1.1	9.6	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
1.0	13.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.9	6.6	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.9	9.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.9	0.9	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.9	9.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.9	8.9	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.8	2.5	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.8	3.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.7	21.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.7	0.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.7	4.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.7	7.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.6	2.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.6	7.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.6	3.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.6	18.7	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.6	6.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.5	1.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.5	5.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.5	10.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.5	3.0	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5	13.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.4	2.7	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.4	15.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.4	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.4	5.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.4	3.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.4	13.4	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.4	0.7	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.3	2.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.3	25.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	5.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	0.3	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.3	4.4	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.3	0.6	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.3	1.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.3	1.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.3	0.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.2	3.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	2.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	1.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	2.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.2	3.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	1.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	4.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	0.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.2	2.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.2	2.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	2.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	0.5	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	4.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	10.9	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	1.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.5	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.0	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.6	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism

Results for Hoxb2_Dlx2

Z-value: 5.48

Motif logo

Transcription factors associated with Hoxb2_Dlx2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hoxb2_Dlx2 motif across conditions

Conditions sorted by the z-value of the Hoxb2_Dlx2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: