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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Hoxb4

Z-value: 1.25

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Transcription factors associated with Hoxb4

Gene Symbol	Gene ID	Gene Info
Hoxb4 Ensembl NCBI MGI UniProt	ENSMUSG00000038692.7	homeobox B4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_96318827_96319554	Hoxb4	923	0.280543	-0.38	4.2e-03	Click!
chr11_96319983_96320134	Hoxb4	1791	0.135156	-0.35	8.1e-03	Click!
chr11_96319651_96319839	Hoxb4	1478	0.164834	-0.33	1.4e-02	Click!
chr11_96318297_96318728	Hoxb4	245	0.764626	-0.30	2.4e-02	Click!

Activity of the Hoxb4 motif across conditions

Conditions sorted by the z-value of the Hoxb4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_152549002_152549525	67.12	Ak5	adenylate kinase 5	22511	0.2
chr11_79753220_79753373	8.98	Mir365-2	microRNA 365-2	26896	0.12
chr1_71938719_71938882	7.93	Gm28818	predicted gene 28818	21675	0.17
chr7_119280318_119280619	6.63	Gm4083	predicted gene 4083	21239	0.18
chr6_56905110_56905280	6.21	Gm3793	predicted gene 3793	1387	0.31
chr10_93882793_93883049	6.15	Metap2	methionine aminopeptidase 2	4565	0.15
chr3_66494840_66495006	5.92	Gm17952	predicted gene, 17952	68628	0.12
chr14_63326009_63326198	5.67	Gm5463	predicted gene 5463	3117	0.21
chr9_83254434_83254631	5.33	Gm27216	predicted gene 27216	8	0.98
chr7_141364479_141364665	5.04	B230206H07Rik	RIKEN cDNA B230206H07 gene	510	0.56
chr17_49423004_49423196	4.94	Mocs1	molybdenum cofactor synthesis 1	5262	0.22
chr19_8928158_8928320	4.91	Rom1	rod outer segment membrane protein 1	1117	0.18
chr15_67016440_67016608	4.88	Gm31342	predicted gene, 31342	23534	0.17
chr6_116650405_116650767	4.82	Depp1	DEPP1 autophagy regulator	23	0.95
chr10_69908447_69908713	4.72	Ank3	ankyrin 3, epithelial	6285	0.32
chrX_162749156_162749312	4.53	Gm23786	predicted gene, 23786	678	0.6
chr11_106486190_106486357	4.53	Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	1523	0.33
chr8_40858144_40858295	4.44	Gm5345	predicted gene 5345	3192	0.19
chr15_30285594_30286020	4.43	Ctnnd2	catenin (cadherin associated protein), delta 2	112669	0.06
chr17_28930772_28931206	4.42	Gm16191	predicted gene 16191	3432	0.11
chr6_37537939_37538090	4.29	Akr1d1	aldo-keto reductase family 1, member D1	1667	0.4
chr10_41209665_41209833	4.23	Gm25526	predicted gene, 25526	6296	0.22
chr10_13521965_13522177	4.22	Pex3	peroxisomal biogenesis factor 3	13890	0.17
chr9_66988315_66988469	4.21	Gm24225	predicted gene, 24225	7207	0.16
chr12_86250272_86250423	4.18	Gpatch2l	G patch domain containing 2 like	6585	0.22
chr11_32251299_32251675	4.14	Nprl3	nitrogen permease regulator-like 3	1209	0.31
chr9_121709940_121710409	4.08	Ss18l2	SS18, nBAF chromatin remodeling complex subunit like 2	155	0.91
chr12_83972157_83972308	4.05	Heatr4	HEAT repeat containing 4	12620	0.09
chr10_17590195_17590550	4.04	Gm47770	predicted gene, 47770	63458	0.1
chr7_49763766_49763917	4.03	Htatip2	HIV-1 Tat interactive protein 2	4688	0.23
chr4_32728069_32728220	4.02	Mdn1	midasin AAA ATPase 1	2244	0.32
chr6_88499789_88500463	3.97	Gm44170	predicted gene, 44170	3479	0.17
chr2_127370032_127370211	3.91	Adra2b	adrenergic receptor, alpha 2b	6835	0.15
chr9_92266891_92267068	3.82	Mir6386	microRNA 6386	382	0.64
chr5_129974852_129975023	3.82	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	2057	0.19
chr5_115627120_115627435	3.80	1110006O24Rik	RIKEN cDNA 1110006O24 gene	4539	0.12
chr10_96616594_96617900	3.75	Btg1	BTG anti-proliferation factor 1	241	0.93
chr11_101669062_101669245	3.66	Arl4d	ADP-ribosylation factor-like 4D	3612	0.12
chr10_62521049_62521209	3.65	Srgn	serglycin	6296	0.14
chr10_60933874_60934228	3.63	Gm26947	predicted gene, 26947	2060	0.24
chr11_102896217_102896397	3.55	Gfap	glial fibrillary acidic protein	824	0.44
chr9_50811130_50811331	3.54	Alg9	asparagine-linked glycosylation 9 (alpha 1,2 mannosyltransferase)	2551	0.2
chrX_162282809_162282976	3.48	Gm27490	predicted gene, 27490	45793	0.16
chr1_185205192_185205398	3.47	Rab3gap2	RAB3 GTPase activating protein subunit 2	1117	0.43
chr1_31094793_31095271	3.46	4931428L18Rik	RIKEN cDNA 4931428L18 gene	1422	0.36
chr6_124471679_124471835	3.43	Gm50463	predicted gene, 50463	4992	0.11
chr1_87961921_87962076	3.35	Usp40	ubiquitin specific peptidase 40	5197	0.13
chr8_84900828_84901106	3.32	Klf1	Kruppel-like factor 1 (erythroid)	961	0.28
chr9_116091571_116091722	3.31	Gm9385	predicted pseudogene 9385	50582	0.13
chr19_10203179_10203536	3.24	Fen1	flap structure specific endonuclease 1	537	0.44
chr18_66449138_66449418	3.22	Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	9255	0.12
chr4_62383795_62384159	3.12	Slc31a1	solute carrier family 31, member 1	1524	0.29
chr7_126260373_126260529	3.11	Sbk1	SH3-binding kinase 1	11589	0.11
chr2_136920981_136921193	3.10	Slx4ip	SLX4 interacting protein	15544	0.17
chr4_141721854_141722005	3.10	Ddi2	DNA-damage inducible protein 2	1490	0.3
chr11_58351240_58351509	3.08	Sh3bp5l	SH3 binding domain protein 5 like	6062	0.1
chrX_166168170_166168321	3.05	Gemin8	gem nuclear organelle associated protein 8	2209	0.35
chr13_84639308_84639992	3.01	Gm26913	predicted gene, 26913	51291	0.18
chr8_88299796_88299987	2.94	Adcy7	adenylate cyclase 7	488	0.81
chr11_106438922_106439089	2.91	Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	48791	0.09
chr8_11008854_11009914	2.90	Irs2	insulin receptor substrate 2	926	0.42
chr4_45522389_45522576	2.89	Shb	src homology 2 domain-containing transforming protein B	7848	0.15
chr17_29859515_29859672	2.86	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	9052	0.17
chr1_39015612_39015763	2.85	Pdcl3	phosducin-like 3	20527	0.15
chr11_31807457_31808119	2.84	D630024D03Rik	RIKEN cDNA D630024D03 gene	16685	0.19
chr15_9472719_9472904	2.75	Gm50456	predicted gene, 50456	2691	0.29
chr10_127657764_127657946	2.69	Stat6	signal transducer and activator of transcription 6	1094	0.28
chr15_97060183_97060372	2.69	Slc38a4	solute carrier family 38, member 4	4321	0.32
chr19_46905032_46905199	2.66	Nt5c2	5'-nucleotidase, cytosolic II	4460	0.2
chr5_105758216_105758376	2.63	Lrrc8d	leucine rich repeat containing 8D	26066	0.16
chr11_64962726_64962996	2.62	Elac2	elaC ribonuclease Z 2	16177	0.22
chr13_94513441_94513654	2.60	Gm25109	predicted gene, 25109	3615	0.25
chr2_167629270_167629508	2.55	Ube2v1	ubiquitin-conjugating enzyme E2 variant 1	2578	0.16
chr5_100638362_100638513	2.55	Coq2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	25982	0.12
chr1_67226652_67226803	2.54	Gm15668	predicted gene 15668	22473	0.2
chr9_32559988_32560144	2.54	Fli1	Friend leukemia integration 1	17205	0.12
chr11_22813575_22813735	2.54	Gm20456	predicted gene 20456	25644	0.1
chr10_95682975_95683126	2.53	Anapc15-ps	anaphase promoting complex C subunit 15, pseudogene	9599	0.12
chr1_167374719_167374895	2.50	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	10641	0.13
chr7_48947261_48947473	2.50	Gm18559	predicted gene, 18559	7249	0.16
chr9_60280023_60280252	2.49	2010001M07Rik	RIKEN cDNA 2010001M07 gene	54005	0.14
chr10_127657981_127658224	2.48	Stat6	signal transducer and activator of transcription 6	1298	0.23
chr7_99170651_99170802	2.47	Dgat2	diacylglycerol O-acyltransferase 2	620	0.63
chr16_97928416_97928567	2.46	C2cd2	C2 calcium-dependent domain containing 2	5858	0.19
chr7_110916018_110916286	2.45	Mrvi1	MRV integration site 1	7551	0.17
chrX_110077792_110077948	2.43	Gm4991	predicted gene 4991	167649	0.04
chr11_87748528_87748688	2.43	Mir142hg	Mir142 host gene (non-protein coding)	6969	0.09
chr18_80258003_80258297	2.41	Slc66a2	solute carrier family 66 member 2	1832	0.22
chr1_185370083_185370248	2.41	Eprs	glutamyl-prolyl-tRNA synthetase	2568	0.16
chr6_101102399_101102550	2.37	Gm43942	predicted gene, 43942	41818	0.12
chr4_109665255_109665548	2.37	Cdkn2c	cyclin dependent kinase inhibitor 2C	29	0.97
chr7_127672339_127672529	2.34	Gm44760	predicted gene 44760	14200	0.08
chr7_75613456_75613616	2.27	Akap13	A kinase (PRKA) anchor protein 13	1152	0.52
chr10_78395785_78396875	2.24	Gm10146	predicted gene 10146	3010	0.11
chr11_64843201_64843493	2.21	Gm12292	predicted gene 12292	406	0.9
chr2_10128665_10128829	2.21	Itih2	inter-alpha trypsin inhibitor, heavy chain 2	1916	0.23
chr1_194773956_194774169	2.19	Plxna2	plexin A2	9495	0.17
chr1_161748259_161748419	2.18	Gm5049	predicted gene 5049	2283	0.24
chr5_45534407_45534776	2.16	Fam184b	family with sequence similarity 184, member B	1951	0.21
chr2_84775312_84775520	2.16	Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	12	0.95
chr5_124226567_124226729	2.11	Pitpnm2os1	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1	3077	0.15
chr12_76673740_76674235	2.09	Sptb	spectrin beta, erythrocytic	36036	0.15
chr17_5099687_5099851	2.09	Gm15599	predicted gene 15599	12341	0.25
chr9_35175147_35176476	2.07	Dcps	decapping enzyme, scavenger	182	0.9
chr11_77752649_77752804	2.07	Gm11191	predicted gene 11191	5685	0.14
chr8_22414458_22414615	2.04	Mrps31	mitochondrial ribosomal protein S31	3138	0.13
chr16_97009796_97010023	2.03	Gm32432	predicted gene, 32432	91152	0.09
chr2_25534285_25534468	2.01	Traf2	TNF receptor-associated factor 2	4764	0.08
chr1_167802317_167803268	1.99	Lmx1a	LIM homeobox transcription factor 1 alpha	113235	0.07
chr12_105009915_105010683	1.99	Syne3	spectrin repeat containing, nuclear envelope family member 3	490	0.67
chr15_84209657_84209833	1.99	Samm50	SAMM50 sorting and assembly machinery component	7520	0.12
chr7_142088957_142089418	1.98	Dusp8	dual specificity phosphatase 8	6085	0.08
chr9_99353166_99353317	1.97	Esyt3	extended synaptotagmin-like protein 3	5277	0.13
chr7_45509067_45509240	1.95	Nucb1	nucleobindin 1	1162	0.19
chr14_69253618_69253952	1.93	Gm27222	predicted gene 27222	5361	0.11
chr18_80160442_80160604	1.93	Gm41787	predicted gene, 41787	2039	0.16
chr13_9019634_9019841	1.93	Gtpbp4	GTP binding protein 4	23654	0.1
chr9_102725851_102726730	1.91	Amotl2	angiomotin-like 2	2041	0.22
chr7_118943210_118943522	1.90	Iqck	IQ motif containing K	6243	0.19
chr11_80146067_80146312	1.88	Tefm	transcription elongation factor, mitochondrial	4014	0.16
chr9_50924434_50924623	1.88	Gm25558	predicted gene, 25558	36578	0.13
chr12_3866694_3867113	1.87	Dnmt3a	DNA methyltransferase 3A	712	0.65
chr14_55540009_55540830	1.87	Pck2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	6	0.92
chrX_160426520_160426808	1.86	Adgrg2	adhesion G protein-coupled receptor G2	628	0.76
chr18_84084539_84085005	1.86	Tshz1	teashirt zinc finger family member 1	303	0.87
chr17_71250184_71250335	1.84	Lpin2	lipin 2	4228	0.18
chr19_21919330_21919481	1.83	Ldhb-ps	lactate dehydrogenase B, pseudogene	17975	0.18
chr4_7195718_7195869	1.83	Gm11804	predicted gene 11804	156279	0.04
chr5_3554322_3554473	1.83	Fam133b	family with sequence similarity 133, member B	5265	0.1
chr17_85103366_85103541	1.83	Camkmt	calmodulin-lysine N-methyltransferase	11370	0.2
chr14_47634410_47634711	1.82	Ktn1	kinectin 1	13888	0.17
chr19_55565985_55566160	1.81	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	175748	0.03
chr5_130024285_130024585	1.81	Asl	argininosuccinate lyase	54	0.96
chr16_36545491_36545642	1.81	Casr	calcium-sensing receptor	16040	0.11
chr2_69135675_69135888	1.78	Nostrin	nitric oxide synthase trafficker	19	0.98
chr8_114117215_114117558	1.76	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	16171	0.27
chr1_91300125_91300350	1.76	Scly	selenocysteine lyase	305	0.82
chr4_33466337_33466819	1.75	Gm11935	predicted gene 11935	13689	0.21
chr8_35406480_35406631	1.75	Gm45301	predicted gene 45301	2951	0.22
chr6_100624120_100624319	1.71	Gm44108	predicted gene, 44108	2721	0.23
chr10_93517827_93518213	1.71	Hal	histidine ammonia lyase	16895	0.12
chr8_117796538_117796693	1.70	Mphosph6	M phase phosphoprotein 6	3398	0.22
chr7_89423229_89423436	1.69	AI314278	expressed sequence AI314278	2974	0.2
chr2_173171192_173172247	1.68	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	18637	0.15
chr12_79641979_79642275	1.67	9430078K24Rik	RIKEN cDNA 9430078K24 gene	282606	0.01
chr18_42510920_42511513	1.65	Tcerg1	transcription elongation regulator 1 (CA150)	271	0.91
chr17_8285201_8285370	1.63	Mpc1	mitochondrial pyruvate carrier 1	831	0.5
chr11_59428195_59428346	1.63	Snap47	synaptosomal-associated protein, 47	19221	0.1
chr7_109114813_109115263	1.63	Gm44781	predicted gene 44781	27849	0.13
chr7_35732533_35732982	1.63	Dpy19l3	dpy-19-like 3 (C. elegans)	2958	0.26
chr9_110676474_110676978	1.62	Gm35715	predicted gene, 35715	1772	0.22
chr5_120471592_120471804	1.61	Sdsl	serine dehydratase-like	1065	0.36
chr13_42342256_42342434	1.58	Gm47118	predicted gene, 47118	37354	0.17
chr5_139484806_139485000	1.58	Zfand2a	zinc finger, AN1-type domain 2A	354	0.83
chr1_24099625_24100848	1.57	Fam135a	family with sequence similarity 135, member A	20	0.87
chr6_88758585_88758947	1.57	Gm43999	predicted gene, 43999	16039	0.11
chr17_42908688_42909025	1.57	Cd2ap	CD2-associated protein	32191	0.22
chr10_127156636_127156787	1.56	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	8514	0.08
chr1_187089072_187089236	1.55	Gm43496	predicted gene 43496	2006	0.23
chr11_109720742_109721454	1.54	Fam20a	family with sequence similarity 20, member A	1158	0.48
chr14_27101808_27102093	1.54	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	12949	0.19
chr10_51453996_51454265	1.52	Gm46189	predicted gene, 46189	1850	0.26
chr17_57279343_57279494	1.51	Vav1	vav 1 oncogene	291	0.85
chr5_24426050_24426729	1.51	Slc4a2	solute carrier family 4 (anion exchanger), member 2	442	0.6
chr15_74909593_74910029	1.51	Ly6m	lymphocyte antigen 6 complex, locus M	12790	0.09
chr7_78941084_78941246	1.51	Gm44815	predicted gene 44815	17279	0.13
chr2_169351742_169351893	1.50	Gm14250	predicted gene 14250	37264	0.17
chrX_12453013_12453173	1.50	Rpl30-ps11	ribosomal protein L30, pseudogene 11	4137	0.31
chr19_43513808_43513959	1.49	Got1	glutamic-oxaloacetic transaminase 1, soluble	1982	0.22
chr3_69812507_69812796	1.49	Sptssb	serine palmitoyltransferase, small subunit B	47271	0.13
chr7_132805104_132805271	1.48	Fam53b	family with sequence similarity 53, member B	2193	0.28
chr15_27496276_27496427	1.47	B230362B09Rik	RIKEN cDNA B230362B09 gene	7561	0.17
chr11_4974790_4975094	1.47	Ap1b1	adaptor protein complex AP-1, beta 1 subunit	11882	0.13
chr10_111637474_111637625	1.46	Gm47864	predicted gene, 47864	12263	0.17
chr9_110343592_110343743	1.45	Scap	SREBF chaperone	532	0.66
chr11_16882016_16882314	1.45	Egfr	epidermal growth factor receptor	4015	0.24
chr17_78379785_78379986	1.41	Fez2	fasciculation and elongation protein zeta 2 (zygin II)	21545	0.15
chrX_13236130_13236460	1.41	2010308F09Rik	RIKEN cDNA 2010308F09 gene	12	0.95
chr18_70562808_70562972	1.41	Mbd2	methyl-CpG binding domain protein 2	5299	0.2
chr6_5281011_5281162	1.40	Pon2	paraoxonase 2	752	0.55
chr7_143313646_143313876	1.40	Gm37364	predicted gene, 37364	16063	0.12
chrX_7444213_7444364	1.40	2010204K13Rik	RIKEN cDNA 2010204K13 gene	855	0.55
chr14_22168765_22168930	1.38	Gm7480	predicted gene 7480	132744	0.04
chr5_145800263_145800414	1.38	Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	5536	0.18
chr1_184051882_184052065	1.38	Dusp10	dual specificity phosphatase 10	17592	0.21
chr2_51933745_51933906	1.38	Rbm43	RNA binding motif protein 43	490	0.77
chr10_76504409_76504560	1.37	Mcm3ap	minichromosome maintenance complex component 3 associated protein	196	0.91
chr11_69366461_69367262	1.37	Chd3	chromodomain helicase DNA binding protein 3	2082	0.14
chr9_43754684_43755222	1.37	Gm30015	predicted gene, 30015	8853	0.16
chr11_115833007_115833489	1.35	Llgl2	LLGL2 scribble cell polarity complex component	677	0.52
chr13_3544999_3545184	1.35	Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	6646	0.16
chrX_162964647_162964798	1.35	S100g	S100 calcium binding protein G	123	0.96
chr16_30187964_30188467	1.34	1700025H01Rik	RIKEN cDNA 1700025H01 gene	6856	0.15
chr13_48731402_48731767	1.34	Rpl17-ps6	ribosomal protein L17, pseudogene 6	31997	0.16
chr12_54205836_54205994	1.33	Egln3	egl-9 family hypoxia-inducible factor 3	2055	0.29
chr2_173976785_173976936	1.33	Atp5k-ps2	ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E, pseudogene 2	7831	0.21
chr8_122452355_122452506	1.32	Gm20735	predicted gene, 20735	1108	0.27
chr18_31227267_31227614	1.32	Rit2	Ras-like without CAAX 2	14708	0.27
chr9_41149387_41149616	1.31	Ubash3b	ubiquitin associated and SH3 domain containing, B	8001	0.14
chr8_20115363_20115545	1.31	Gm21769	predicted gene, 21769	6930	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.7	3.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.5	1.6	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.5	1.5	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.5	1.4	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.4	1.8	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.4	1.8	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.4	1.3	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.4	1.5	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.4	1.4	GO:0001887	selenium compound metabolic process(GO:0001887)
0.3	1.7	GO:0006116	NADH oxidation(GO:0006116)
0.3	1.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.3	1.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3	0.9	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.3	1.2	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.3	2.0	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3	1.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.3	0.9	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.3	1.4	GO:0060023	soft palate development(GO:0060023)
0.3	1.7	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.3	1.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3	1.4	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.3	1.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.3	2.4	GO:0071361	cellular response to ethanol(GO:0071361)
0.3	0.8	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.2	0.7	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.2	13.3	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
0.2	0.8	GO:0006526	arginine biosynthetic process(GO:0006526)
0.2	0.4	GO:0021564	vagus nerve development(GO:0021564)
0.2	0.8	GO:0015819	lysine transport(GO:0015819)
0.2	0.8	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.2	0.6	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.2	1.7	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2	0.7	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2	1.8	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2	1.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2	1.1	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2	0.7	GO:0071896	protein localization to adherens junction(GO:0071896)
0.2	0.5	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2	1.4	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.2	0.3	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.4	GO:0006533	aspartate catabolic process(GO:0006533)
0.1	0.9	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.1	0.4	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	1.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.6	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	0.7	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.7	GO:0016139	glycoside catabolic process(GO:0016139)
0.1	0.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	1.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.4	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1	0.3	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	0.4	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.4	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	2.6	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.1	0.4	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.3	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1	0.4	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.4	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	1.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.3	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.3	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1	0.7	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.4	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.6	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1	0.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.4	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.6	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.1	0.3	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.9	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.4	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.1	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.1	0.8	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.4	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.1	0.2	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	1.0	GO:0070166	enamel mineralization(GO:0070166)
0.1	0.2	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.2	GO:1902414	protein localization to cell junction(GO:1902414)
0.1	0.2	GO:1903935	response to sodium arsenite(GO:1903935)
0.1	0.5	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	1.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.1	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1	0.4	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.4	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.7	GO:0002097	tRNA wobble base modification(GO:0002097)
0.1	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.4	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.1	0.4	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.1	0.4	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1	0.3	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.4	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	0.5	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	0.2	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698)
0.1	0.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.2	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.1	0.1	GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1	0.2	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	1.6	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.1	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.1	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.1	0.8	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.1	0.2	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.1	0.2	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1	0.8	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.2	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1	0.2	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.8	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.3	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.2	GO:0072602	interleukin-4 secretion(GO:0072602)
0.1	0.3	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	1.4	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.1	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.5	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	0.1	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1	0.3	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.1	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.1	GO:0002432	granuloma formation(GO:0002432)
0.1	1.2	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	0.2	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.1	0.3	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.4	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1	0.2	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.2	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.1	0.9	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.2	GO:0044026	DNA hypermethylation(GO:0044026)
0.1	0.4	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.1	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.2	GO:1902534	single-organism membrane invagination(GO:1902534)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.2	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.4	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.2	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.2	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.2	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.2	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.2	GO:0030578	PML body organization(GO:0030578)
0.0	0.0	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.2	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.2	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.2	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.7	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.5	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.9	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.0	0.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	2.4	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0	0.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.4	GO:0071801	regulation of podosome assembly(GO:0071801)
0.0	0.4	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.5	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.8	GO:0006301	postreplication repair(GO:0006301)
0.0	0.3	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.3	GO:0072539	T-helper 17 cell differentiation(GO:0072539)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.0	0.3	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.5	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:2000510	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.0	0.2	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0	0.6	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.4	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.3	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.1	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.5	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.2	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.3	GO:0032620	interleukin-17 production(GO:0032620)
0.0	0.1	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0	0.0	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.3	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.8	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.3	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.2	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.3	GO:0040034	regulation of development, heterochronic(GO:0040034)
0.0	0.0	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.8	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.3	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.5	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.0	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.1	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.2	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0046132	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) pyrimidine ribonucleotide biosynthetic process(GO:0009220) UMP metabolic process(GO:0046049) pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.4	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.3	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.2	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.0	0.7	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	1.2	GO:0051168	nuclear export(GO:0051168)
0.0	0.1	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.0	GO:1904339	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of dopaminergic neuron differentiation(GO:1904338) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.2	GO:0045760	positive regulation of action potential(GO:0045760)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	1.8	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.6	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.1	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.0	GO:0051031	tRNA transport(GO:0051031)
0.0	0.2	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.0	0.2	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.1	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.4	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.3	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.7	GO:0046785	microtubule polymerization(GO:0046785)
0.0	0.3	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.0	0.3	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	1.9	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.0	GO:0061009	common bile duct development(GO:0061009)
0.0	0.1	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.0	GO:0031052	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.0	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.3	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.0	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.0	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.0	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.0	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.0	GO:0003166	His-Purkinje system development(GO:0003164) bundle of His development(GO:0003166)
0.0	0.0	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.0	GO:0052204	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.7	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	0.4	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	0.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0	0.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.0	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0	0.1	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.0	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.2	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.3	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.1	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	0.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.3	GO:0051693	actin filament capping(GO:0051693)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.4	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:1901724	positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.0	0.1	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.0	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.2	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.6	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.0	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001)
0.0	0.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.0	GO:0036394	amylase secretion(GO:0036394)
0.0	1.5	GO:0006457	protein folding(GO:0006457)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.0	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.0	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.0	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.0	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0	0.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.2	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.7	GO:0010950	positive regulation of endopeptidase activity(GO:0010950)
0.0	0.0	GO:1901722	regulation of cell proliferation involved in kidney development(GO:1901722)
0.0	0.2	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.0	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.0	GO:1904938	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.0	GO:0014028	notochord formation(GO:0014028)
0.0	0.0	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.0	GO:0002337	B-1 B cell differentiation(GO:0001923) B-1a B cell differentiation(GO:0002337)
0.0	0.3	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.1	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.1	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.2	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	0.0	GO:0033700	phospholipid efflux(GO:0033700)
0.0	0.1	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.4	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	0.0	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.0	GO:2000416	regulation of eosinophil migration(GO:2000416)
0.0	0.3	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	1.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.1	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.4	1.6	GO:0097450	astrocyte end-foot(GO:0097450)
0.3	1.3	GO:1990130	Iml1 complex(GO:1990130)
0.3	3.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3	1.6	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.3	1.4	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	0.7	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	0.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.2	2.2	GO:0070852	cell body fiber(GO:0070852)
0.1	1.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.4	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.9	GO:0051286	cell tip(GO:0051286)
0.1	0.5	GO:0097422	tubular endosome(GO:0097422)
0.1	1.1	GO:0032797	SMN complex(GO:0032797)
0.1	0.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.6	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.5	GO:0042629	mast cell granule(GO:0042629)
0.1	1.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.2	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.2	GO:0097443	sorting endosome(GO:0097443)
0.1	0.3	GO:1990745	EARP complex(GO:1990745)
0.1	0.4	GO:0097255	R2TP complex(GO:0097255)
0.1	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.3	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.5	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.6	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.9	GO:0001741	XY body(GO:0001741)
0.1	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.5	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.3	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	2.4	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.5	GO:0060091	kinocilium(GO:0060091)
0.0	0.5	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	2.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	1.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.4	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	1.7	GO:0005776	autophagosome(GO:0005776)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0031261	DNA replication preinitiation complex(GO:0031261)
0.0	0.1	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	3.3	GO:0072562	blood microparticle(GO:0072562)
0.0	0.6	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.4	GO:0043196	varicosity(GO:0043196)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	1.7	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0097386	glial cell projection(GO:0097386)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	1.1	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.9	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	12.7	GO:0005815	microtubule organizing center(GO:0005815)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	1.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0097440	apical dendrite(GO:0097440)
0.0	1.5	GO:0000502	proteasome complex(GO:0000502)
0.0	0.0	GO:0005767	secondary lysosome(GO:0005767) phagolysosome(GO:0032010)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	1.2	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.5	GO:0015030	Cajal body(GO:0015030)
0.0	3.0	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	1.5	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	8.8	GO:0005730	nucleolus(GO:0005730)
0.0	0.1	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.3	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.2	GO:0035869	ciliary transition zone(GO:0035869)
0.0	1.7	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.0	GO:0061689	tricellular tight junction(GO:0061689)
0.0	1.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	13.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.7	2.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.7	2.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.6	1.7	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.5	1.9	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.4	1.2	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.3	1.6	GO:0035671	enone reductase activity(GO:0035671)
0.3	1.5	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3	1.8	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.3	0.9	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.3	1.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3	0.8	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2	0.7	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.2	0.7	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.2	1.4	GO:0005499	vitamin D binding(GO:0005499)
0.2	2.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	0.8	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	2.0	GO:0004016	adenylate cyclase activity(GO:0004016)
0.2	0.6	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2	0.6	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.2	1.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.2	0.9	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.2	0.6	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2	0.9	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	1.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	1.5	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	1.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	0.8	GO:0051525	NFAT protein binding(GO:0051525)
0.1	1.3	GO:0070513	death domain binding(GO:0070513)
0.1	0.4	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	1.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.5	GO:0034548	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1	0.4	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.1	0.4	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.7	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0038181	bile acid receptor activity(GO:0038181)
0.1	2.2	GO:0001848	complement binding(GO:0001848)
0.1	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.4	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.7	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	1.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.4	GO:0031720	haptoglobin binding(GO:0031720)
0.1	1.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	1.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1	1.3	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.4	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.3	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.4	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.3	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.1	2.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.2	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.1	0.3	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	0.2	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.7	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0008252	nucleotidase activity(GO:0008252)
0.1	0.9	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.2	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.2	GO:0030984	kininogen binding(GO:0030984)
0.1	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.8	GO:0048038	quinone binding(GO:0048038)
0.1	0.5	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	0.4	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.7	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.1	0.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.1	1.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	1.2	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.3	GO:1990254	keratin filament binding(GO:1990254)
0.1	1.1	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1	1.7	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1	0.3	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1	0.4	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	0.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.2	GO:0019808	polyamine binding(GO:0019808)
0.1	0.6	GO:0005123	death receptor binding(GO:0005123)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.1	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	1.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	1.3	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.4	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.8	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.0	0.3	GO:0035197	siRNA binding(GO:0035197)
0.0	0.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	1.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.7	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	1.2	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.3	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.6	GO:0015928	fucosidase activity(GO:0015928)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	1.1	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.8	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	2.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
0.0	0.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	1.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0043915	phosphorylase kinase regulator activity(GO:0008607) cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.7	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.5	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.9	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	1.7	GO:0005550	pheromone binding(GO:0005550)
0.0	2.5	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.0	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0043199	sulfate binding(GO:0043199)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.0	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.5	GO:0043022	ribosome binding(GO:0043022)
0.0	0.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.4	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.0	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	1.2	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.1	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.9	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995) oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity(GO:0030487)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.5	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.0	1.0	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0043765	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0	0.4	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.6	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.0	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.0	GO:0097108	smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.1	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.6	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0034796	acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.8	GO:0001047	core promoter binding(GO:0001047)
0.0	0.0	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	2.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	2.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	0.1	ST ADRENERGIC	Adrenergic Pathway
0.1	1.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	2.5	PID E2F PATHWAY	E2F transcription factor network
0.0	2.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	1.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	4.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.0	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	13.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	2.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	1.6	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	1.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	2.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	1.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	3.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.8	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	0.6	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	2.6	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	0.6	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	1.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	0.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.0	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	2.1	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.5	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	3.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.0	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.1	REACTOME BIOLOGICAL OXIDATIONS	Genes involved in Biological oxidations
0.0	0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Results for Hoxb4

Z-value: 1.25

Motif logo

Transcription factors associated with Hoxb4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Hoxb4 motif across conditions

Conditions sorted by the z-value of the Hoxb4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: