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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Irf3

Z-value: 2.10

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Transcription factors associated with Irf3

Gene Symbol	Gene ID	Gene Info
Irf3 Ensembl NCBI MGI UniProt	ENSMUSG00000003184.8	interferon regulatory factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_44997793_44998029	Irf3	38	0.786164	0.65	9.3e-08	Click!
chr7_44999860_45000011	Irf3	232	0.745342	0.10	4.8e-01	Click!
chr7_45000798_45000949	Irf3	125	0.865469	0.02	9.0e-01	Click!

Activity of the Irf3 motif across conditions

Conditions sorted by the z-value of the Irf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_4543069_4543227	20.34	Mtmr3	myotubularin related protein 3	3120	0.23
chr16_58661948_58662241	19.17	Gm49701	predicted gene, 49701	6850	0.13
chr5_36726254_36726643	18.73	Gm43701	predicted gene 43701	22170	0.11
chr1_180261995_180262146	16.21	Psen2	presenilin 2	1368	0.35
chrX_101428817_101430172	15.85	Nono	non-POU-domain-containing, octamer binding protein	61	0.96
chr11_86581327_86581590	15.68	Mir21a	microRNA 21a	2700	0.21
chr3_105808565_105808856	15.05	Gm5547	predicted gene 5547	6830	0.11
chr11_86581594_86581768	15.00	Mir21a	microRNA 21a	2477	0.22
chr13_59820217_59820403	14.83	Tut7	terminal uridylyl transferase 7	2278	0.17
chr15_77922797_77923125	14.29	Txn2	thioredoxin 2	4774	0.17
chr6_127245874_127246080	14.19	Gm43635	predicted gene 43635	8667	0.13
chr11_58214634_58215080	14.12	Irgm2	immunity-related GTPase family M member 2	151	0.92
chr8_46546459_46546652	13.61	Cenpu	centromere protein U	5473	0.17
chr11_95339762_95339938	13.16	Fam117a	family with sequence similarity 117, member A	81	0.95
chr17_36020770_36020975	12.96	H2-T24	histocompatibility 2, T region locus 24	312	0.69
chr9_32906251_32906426	12.57	Gm27162	predicted gene 27162	22628	0.19
chr6_38900912_38901211	12.51	Tbxas1	thromboxane A synthase 1, platelet	17919	0.19
chr17_36121540_36121726	12.39	Gm19684	predicted gene, 19684	45	0.63
chr9_107975396_107975585	12.21	Uba7	ubiquitin-like modifier activating enzyme 7	15	0.92
chr17_36023721_36023895	11.44	H2-T24	histocompatibility 2, T region locus 24	3248	0.08
chr4_150784726_150784890	11.22	Gm13049	predicted gene 13049	40925	0.13
chr11_58199487_58199685	11.08	Igtp	interferon gamma induced GTPase	0	0.5
chr14_55577823_55578992	10.53	Psme1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	2	0.91
chr2_167697961_167698142	10.43	A530013C23Rik	RIKEN cDNA A530013C23 gene	6870	0.12
chr9_35175147_35176476	10.25	Dcps	decapping enzyme, scavenger	182	0.9
chr14_25686636_25686805	10.18	Ppif	peptidylprolyl isomerase F (cyclophilin F)	7434	0.14
chr15_74989440_74989591	10.15	Gm37042	predicted gene, 37042	765	0.35
chr10_80948620_80948940	9.94	Gm3828	predicted gene 3828	5930	0.1
chr5_103760139_103760316	9.93	Aff1	AF4/FMR2 family, member 1	5654	0.23
chr11_119392977_119393557	9.78	Rnf213	ring finger protein 213	167	0.93
chr9_123845102_123845518	9.27	Fyco1	FYVE and coiled-coil domain containing 1	704	0.59
chr3_127893994_127894286	9.08	Fam241a	family with sequence similarity 241, member A	2148	0.22
chr17_33919383_33920010	9.05	Tapbp	TAP binding protein	59	0.83
chr10_95297705_95298060	8.99	Gm48880	predicted gene, 48880	16971	0.14
chr17_36042796_36043034	8.85	Gm6034	predicted gene 6034	46	0.63
chr4_136187071_136187247	8.74	E2f2	E2F transcription factor 2	6376	0.15
chr12_26460219_26460410	8.47	Rsad2	radical S-adenosyl methionine domain containing 2	3862	0.17
chr18_84906326_84906549	8.33	Fbxo15	F-box protein 15	28345	0.13
chr8_25609113_25609264	8.27	Gm23184	predicted gene, 23184	1370	0.25
chr6_38338044_38338499	8.20	Zc3hav1	zinc finger CCCH type, antiviral 1	16002	0.12
chr15_77397415_77397965	8.18	Apol7a	apolipoprotein L 7a	756	0.47
chr8_116581419_116581617	8.18	Dynlrb2	dynein light chain roadblock-type 2	76503	0.1
chr19_6046015_6046240	8.06	Syvn1	synovial apoptosis inhibitor 1, synoviolin	449	0.48
chr15_36648029_36648244	8.02	Gm6704	predicted gene 6704	18267	0.12
chr5_114897341_114897492	7.91	Oasl2	2'-5' oligoadenylate synthetase-like 2	116	0.92
chr4_154928100_154928296	7.84	Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	4	0.96
chr8_122306282_122306514	7.78	Zfpm1	zinc finger protein, multitype 1	922	0.5
chr2_162930645_162930796	7.74	Srsf6	serine and arginine-rich splicing factor 6	808	0.51
chr12_84969806_84969957	7.72	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	943	0.35
chr6_38533231_38533979	7.58	Fmc1	formation of mitochondrial complex V assembly factor 1	103	0.96
chr16_18428507_18428684	7.43	Txnrd2	thioredoxin reductase 2	102	0.93
chr1_153770335_153770651	7.37	Rnasel	ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)	14509	0.1
chr5_92353466_92353617	7.35	Cxcl10	chemokine (C-X-C motif) ligand 10	4652	0.11
chr15_76243373_76243550	7.34	Parp10	poly (ADP-ribose) polymerase family, member 10	20	0.93
chr2_84798993_84799537	7.16	Ube2l6	ubiquitin-conjugating enzyme E2L 6	431	0.71
chr12_78980719_78981012	6.99	Tmem229b	transmembrane protein 229B	87	0.97
chr4_86902253_86902422	6.93	Acer2	alkaline ceramidase 2	27923	0.18
chr6_67170285_67170790	6.88	A430010J10Rik	RIKEN cDNA A430010J10 gene	5334	0.17
chr5_137306965_137308105	6.85	Srrt	serrate RNA effector molecule homolog (Arabidopsis)	62	0.92
chr2_85047884_85048082	6.79	Tnks1bp1	tankyrase 1 binding protein 1	39	0.96
chr12_111515021_111515172	6.76	Gm40578	predicted gene, 40578	14256	0.1
chr7_78913903_78914305	6.73	Isg20	interferon-stimulated protein	123	0.94
chr5_120812476_120812687	6.73	Oas1b	2'-5' oligoadenylate synthetase 1B	54	0.5
chr11_100704167_100704329	6.68	Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	5	0.95
chr6_143751347_143751526	6.67	1700060C16Rik	RIKEN cDNA 1700060C16 gene	100148	0.08
chr1_67092586_67092737	6.66	Cps1	carbamoyl-phosphate synthetase 1	30365	0.17
chr14_60171561_60171774	6.66	Atp8a2	ATPase, aminophospholipid transporter-like, class I, type 8A, member 2	5872	0.15
chr10_81496759_81496938	6.64	Ncln	nicalin	456	0.57
chr11_74622356_74622521	6.60	Ccdc92b	coiled-coil domain containing 92B	2833	0.22
chr7_126607127_126607307	6.46	Il27	interleukin 27	12276	0.07
chr2_170153397_170153978	6.38	Zfp217	zinc finger protein 217	5584	0.31
chr7_104244275_104244625	6.30	Trim34a	tripartite motif-containing 34A	7	0.94
chr16_10732413_10732740	6.10	Gm15558	predicted gene 15558	49037	0.07
chr5_105110188_105110546	6.08	Gbp9	guanylate-binding protein 9	90	0.97
chr19_45208051_45208464	6.04	Lbx1	ladybird homeobox 1	27555	0.14
chr1_195092219_195092480	6.04	Cd46	CD46 antigen, complement regulatory protein	100	0.95
chr2_26089089_26089249	6.00	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing	1206	0.38
chr11_57962679_57963326	5.93	Gm12249	predicted gene 12249	10132	0.15
chr7_46830743_46831064	5.92	Gm45308	predicted gene 45308	1561	0.21
chr18_32559402_32560290	5.79	Gypc	glycophorin C	134	0.97
chr10_121586932_121587331	5.78	Tbk1	TANK-binding kinase 1	344	0.83
chr2_6444750_6445068	5.74	Gm13388	predicted gene 13388	8876	0.17
chr6_122394205_122394556	5.72	1700063H04Rik	RIKEN cDNA 1700063H04 gene	3001	0.17
chr5_137115775_137116361	5.70	Trim56	tripartite motif-containing 56	139	0.93
chr7_116285322_116285500	5.61	Gm44867	predicted gene 44867	2526	0.23
chr11_72301460_72301663	5.52	Xaf1	XIAP associated factor 1	68	0.95
chr1_79752855_79753006	5.51	Wdfy1	WD repeat and FYVE domain containing 1	8791	0.17
chr2_155541250_155541401	5.48	Mipep-ps	mitochondrial intermediate peptidase, pseudogene	1322	0.24
chr14_20478827_20479017	5.47	Anxa7	annexin A7	986	0.42
chr5_63823714_63823894	5.45	0610040J01Rik	RIKEN cDNA 0610040J01 gene	11284	0.2
chr3_127123331_127123826	5.43	Ank2	ankyrin 2, brain	1284	0.39
chr19_41345544_41345700	5.38	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	39474	0.17
chr9_114752784_114753499	5.33	Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	21968	0.13
chr6_38353782_38354731	5.29	Zc3hav1	zinc finger CCCH type, antiviral 1	17	0.97
chr13_42051896_42052956	5.21	Hivep1	human immunodeficiency virus type I enhancer binding protein 1	22	0.98
chr17_46889460_46890097	5.20	Tbcc	tubulin-specific chaperone C	906	0.51
chr16_35938456_35939088	5.18	Parp9	poly (ADP-ribose) polymerase family, member 9	239	0.62
chr5_29893936_29894092	5.16	Gm42450	predicted gene 42450	2050	0.31
chr2_24385099_24385869	5.15	Psd4	pleckstrin and Sec7 domain containing 4	131	0.95
chr9_58249475_58249881	5.15	Pml	promyelocytic leukemia	13	0.96
chr15_74930453_74930628	5.13	Gm39556	predicted gene, 39556	1103	0.31
chr7_102565432_102565621	5.07	Trim21	tripartite motif-containing 21	40	0.93
chr6_34863037_34863250	5.06	Tmem140	transmembrane protein 140	3	0.96
chr15_102296754_102296921	5.02	Espl1	extra spindle pole bodies 1, separase	532	0.42
chr11_100402292_100402625	4.98	Gm12348	predicted gene 12348	950	0.31
chr5_20945137_20945297	4.97	Rsbn1l	round spermatid basic protein 1-like	287	0.89
chr16_30959800_30959970	4.96	Gm15742	predicted gene 15742	13633	0.17
chr10_121580489_121580640	4.93	Tbk1	TANK-binding kinase 1	6177	0.15
chr9_109054683_109055091	4.84	Shisa5	shisa family member 5	24	0.95
chr11_119394402_119394553	4.81	Rnf213	ring finger protein 213	1377	0.33
chr6_31642445_31643002	4.80	Gm43154	predicted gene 43154	8318	0.19
chr1_31096747_31096898	4.73	4931428L18Rik	RIKEN cDNA 4931428L18 gene	368	0.84
chr14_21853898_21854077	4.71	Comtd1	catechol-O-methyltransferase domain containing 1	5010	0.14
chr6_38342333_38342771	4.68	Zc3hav1	zinc finger CCCH type, antiviral 1	11721	0.13
chr7_75612084_75612766	4.66	Akap13	A kinase (PRKA) anchor protein 13	141	0.96
chr4_140679856_140680032	4.59	Gm13025	predicted gene 13025	191	0.91
chr7_118129449_118130261	4.53	Arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1	193	0.93
chr14_37163999_37164150	4.51	Gm18834	predicted gene, 18834	18991	0.15
chr5_100656535_100656686	4.48	Coq2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	7809	0.15
chr16_90988770_90988947	4.44	Gm15965	predicted gene 15965	4951	0.12
chr11_65777037_65777188	4.40	Map2k4	mitogen-activated protein kinase kinase 4	11173	0.21
chr12_98746733_98746999	4.34	Zc3h14	zinc finger CCCH type containing 14	98	0.95
chr11_22871975_22872126	4.34	Gm24917	predicted gene, 24917	3149	0.16
chr7_24380530_24380681	4.31	Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	1565	0.21
chr19_55865164_55865315	4.25	Ppnr	per-pentamer repeat gene	23567	0.21
chr17_87638274_87638425	4.24	Epcam	epithelial cell adhesion molecule	1667	0.38
chr5_135168094_135168944	4.19	Bcl7b	B cell CLL/lymphoma 7B	74	0.95
chr11_53423074_53423393	4.17	Leap2	liver-expressed antimicrobial peptide 2	63	0.93
chr4_86690175_86690553	4.17	Plin2	perilipin 2	20304	0.17
chr11_48871235_48871826	4.17	Irgm1	immunity-related GTPase family M member 1	110	0.93
chr6_39381267_39381418	4.14	Rab19	RAB19, member RAS oncogene family	167	0.93
chr14_52103963_52104507	4.10	Hnrnpc	heterogeneous nuclear ribonucleoprotein C	207	0.88
chr8_46844739_46844892	4.09	Gm45481	predicted gene 45481	10903	0.18
chr2_167061965_167062856	4.07	Znfx1	zinc finger, NFX1-type containing 1	229	0.66
chr13_77548432_77549057	4.07	Gm9634	predicted gene 9634	5629	0.31
chr7_118756592_118756841	4.06	Vps35l	VPS35 endosomal protein sorting factor like	4053	0.14
chr7_132811860_132812052	4.04	Fam53b	family with sequence similarity 53, member B	1139	0.45
chr3_104817474_104818824	4.00	Mov10	Mov10 RISC complex RNA helicase	33	0.95
chr17_34204420_34204645	3.96	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	35	0.87
chr5_105598967_105599118	3.95	C230066G23Rik	RIKEN cDNA C230066G23 gene	18602	0.19
chr5_134966335_134966938	3.93	Cldn3	claudin 3	19578	0.07
chr7_123397485_123397636	3.92	Lcmt1	leucine carboxyl methyltransferase 1	10620	0.17
chr17_83747854_83748005	3.90	Mta3	metastasis associated 3	7705	0.24
chr6_94743069_94743231	3.89	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	42992	0.13
chr2_90894414_90894603	3.80	Gm32514	predicted gene, 32514	1310	0.26
chr15_79062847_79063320	3.80	Ankrd54	ankyrin repeat domain 54	190	0.84
chr19_18692041_18692250	3.78	Carnmt1	carnosine N-methyltransferase 1	20816	0.13
chr17_34198241_34198411	3.77	Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	44	0.92
chr19_4503888_4504039	3.72	2010003K11Rik	RIKEN cDNA 2010003K11 gene	5380	0.14
chr11_53859007_53859393	3.70	Gm12216	predicted gene 12216	29	0.96
chr13_58158180_58158751	3.67	Idnk	idnK gluconokinase homolog (E. coli)	782	0.36
chr4_145246773_145246990	3.60	Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	11	0.98
chr1_61374362_61374513	3.59	9530026F06Rik	RIKEN cDNA 9530026F06 gene	3995	0.24
chr1_161748259_161748419	3.59	Gm5049	predicted gene 5049	2283	0.24
chr16_14308796_14308970	3.59	Gm15868	predicted gene 15868	2958	0.2
chr8_34158314_34158519	3.59	Saraf	store-operated calcium entry-associated regulatory factor	65	0.95
chr1_105971738_105972167	3.58	Gm18801	predicted gene, 18801	15642	0.14
chr4_154297804_154298100	3.57	Arhgef16	Rho guanine nucleotide exchange factor (GEF) 16	1940	0.29
chr4_57130427_57130578	3.57	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	7690	0.23
chr7_29030418_29030583	3.57	Gm38979	predicted gene, 38979	1477	0.24
chr6_39264655_39265049	3.56	Gm26008	predicted gene, 26008	1090	0.47
chr8_84974849_84975028	3.56	AC163703.1		1604	0.14
chr5_129500699_129500850	3.55	Gm40332	predicted gene, 40332	227	0.71
chr3_60408983_60409147	3.53	Mbnl1	muscleblind like splicing factor 1	63765	0.12
chr13_112073928_112074288	3.53	Gm31104	predicted gene, 31104	64008	0.09
chr9_20868539_20869028	3.50	Shfl	shiftless antiviral inhibitor of ribosomal frameshifting	103	0.92
chr14_76673707_76673858	3.48	1700108F19Rik	RIKEN cDNA 1700108F19 gene	819	0.66
chr4_56892851_56893002	3.47	Mir32	microRNA 32	2372	0.2
chr11_21994299_21994805	3.43	Otx1	orthodenticle homeobox 1	7063	0.25
chr4_156200724_156201012	3.41	Isg15	ISG15 ubiquitin-like modifier	72	0.93
chr5_121469594_121469759	3.41	Gm15546	predicted gene 15546	2712	0.13
chr8_46611647_46611798	3.40	Primpol	primase and polymerase (DNA-directed)	1293	0.37
chr18_5603185_5603788	3.38	Zeb1	zinc finger E-box binding homeobox 1	258	0.88
chr15_39113027_39113251	3.37	Dcaf13	DDB1 and CUL4 associated factor 13	274	0.62
chr4_136213729_136213912	3.36	Asap3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	7455	0.15
chr9_62343227_62343790	3.34	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	555	0.78
chr1_190832275_190832426	3.33	Rps6kc1	ribosomal protein S6 kinase polypeptide 1	1686	0.44
chr11_59184195_59184346	3.33	Guk1	guanylate kinase 1	584	0.48
chr11_94589805_94589967	3.30	Acsf2	acyl-CoA synthetase family member 2	11883	0.11
chr6_128362791_128363670	3.29	Foxm1	forkhead box M1	263	0.49
chr3_131266526_131266677	3.28	Hadh	hydroxyacyl-Coenzyme A dehydrogenase	5423	0.17
chr10_95623626_95623777	3.27	Gm33336	predicted gene, 33336	8538	0.13
chr11_55113548_55113800	3.21	Atp5pb-ps	ATP synthase peripheral stalk-membrane subunit b, pseudogene	5121	0.13
chr13_46735814_46736188	3.20	Nup153	nucleoporin 153	8061	0.17
chr6_39117795_39118421	3.17	Parp12	poly (ADP-ribose) polymerase family, member 12	241	0.62
chr9_106367425_106368835	3.16	Dusp7	dual specificity phosphatase 7	502	0.7
chr2_32115882_32116037	3.12	Plpp7	phospholipid phosphatase 7 (inactive)	19804	0.1
chr5_140034121_140034770	3.12	Gm43702	predicted gene 43702	2269	0.28
chr2_25546540_25546764	3.11	Traf2	TNF receptor-associated factor 2	258	0.77
chrX_94212852_94213030	3.10	Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	79	0.97
chr6_142752495_142752646	3.09	Cmas	cytidine monophospho-N-acetylneuraminic acid synthetase	4116	0.23
chr6_86547859_86548409	3.07	1600020E01Rik	RIKEN cDNA 1600020E01 gene	153	0.91
chr2_163710865_163711016	3.06	Pkig	protein kinase inhibitor, gamma	16902	0.13
chr17_26511994_26512145	3.04	Dusp1	dual specificity phosphatase 1	3550	0.13
chr5_132466431_132466777	3.01	Auts2	autism susceptibility candidate 2	17244	0.12
chr16_91056144_91056326	2.97	4931406G06Rik	RIKEN cDNA 4931406G06 gene	11579	0.1
chr11_109362305_109363665	2.94	Gna13	guanine nucleotide binding protein, alpha 13	154	0.59
chr14_32861100_32861956	2.93	Vstm4	V-set and transmembrane domain containing 4	4772	0.2
chr2_38998173_38998600	2.92	Wdr38	WD repeat domain 38	54	0.59
chr10_127676686_127677194	2.91	Nemp1	nuclear envelope integral membrane protein 1	124	0.61

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	15.6	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.9	19.4	GO:0032020	ISG15-protein conjugation(GO:0032020)
2.3	6.9	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
2.1	6.4	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
1.9	5.8	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
1.7	6.7	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
1.6	4.7	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
1.5	10.8	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.5	7.7	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
1.5	4.6	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.5	7.6	GO:0061635	regulation of protein complex stability(GO:0061635)
1.5	5.9	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.4	4.2	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
1.3	4.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
1.3	12.6	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
1.2	3.7	GO:0090365	regulation of mRNA modification(GO:0090365)
1.1	6.8	GO:0031053	primary miRNA processing(GO:0031053)
1.0	3.8	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.9	8.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.9	1.7	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
0.8	5.0	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.8	5.7	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.8	2.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.8	5.5	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7	1.4	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.7	6.3	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.7	2.7	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.7	2.7	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.6	2.5	GO:0007296	vitellogenesis(GO:0007296)
0.6	18.4	GO:0042832	defense response to protozoan(GO:0042832)
0.6	2.4	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.6	16.0	GO:0035456	response to interferon-beta(GO:0035456)
0.6	2.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.5	2.1	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.5	1.6	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5	1.0	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.5	1.5	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.5	4.1	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.5	1.5	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.5	2.4	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.5	6.1	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.5	1.4	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.5	1.4	GO:0001692	histamine metabolic process(GO:0001692)
0.4	1.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.4	3.4	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.4	2.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.4	3.2	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.4	1.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.4	2.8	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.4	1.2	GO:0002432	granuloma formation(GO:0002432)
0.4	2.7	GO:1901970	positive regulation of mitotic sister chromatid separation(GO:1901970)
0.4	1.5	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.4	1.5	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.4	1.1	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.4	3.7	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.4	1.8	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.4	1.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.4	1.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.3	10.5	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.3	1.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.3	2.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3	1.3	GO:1904672	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.3	2.3	GO:0044539	long-chain fatty acid import(GO:0044539)
0.3	7.2	GO:0000305	response to oxygen radical(GO:0000305)
0.3	2.5	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.3	4.7	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3	2.8	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.3	0.9	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.3	3.9	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.3	0.6	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.3	0.9	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.3	3.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3	1.2	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3	0.9	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3	6.6	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.3	1.4	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.3	2.5	GO:0032966	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966)
0.3	1.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.3	0.5	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.3	2.4	GO:0000103	sulfate assimilation(GO:0000103)
0.3	4.0	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.3	0.8	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.3	0.8	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2	1.0	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.2	1.2	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2	0.5	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2	4.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.2	0.9	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2	1.2	GO:1903147	negative regulation of mitophagy(GO:1903147)
0.2	0.5	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2	1.6	GO:0042772	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2	1.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.7	GO:0006481	C-terminal protein methylation(GO:0006481)
0.2	0.5	GO:0019659	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2	0.7	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.2	1.3	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.2	2.4	GO:0019985	translesion synthesis(GO:0019985)
0.2	0.6	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.2	1.0	GO:2000210	positive regulation of anoikis(GO:2000210)
0.2	2.0	GO:0006517	protein deglycosylation(GO:0006517)
0.2	2.5	GO:0009992	cellular water homeostasis(GO:0009992)
0.2	1.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2	1.0	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2	0.6	GO:0030578	PML body organization(GO:0030578)
0.2	0.6	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2	0.8	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.2	2.2	GO:0042407	cristae formation(GO:0042407)
0.2	0.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.2	1.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2	0.4	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2	2.5	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.2	0.7	GO:0051031	tRNA transport(GO:0051031)
0.2	2.1	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	5.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2	1.4	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.2	0.9	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.2	0.7	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	1.9	GO:0000042	protein targeting to Golgi(GO:0000042)
0.2	0.3	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.2	0.5	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	1.3	GO:1904406	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.2	0.7	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.2	0.5	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2	0.3	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.2	0.2	GO:0001796	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.2	0.3	GO:2001182	regulation of interleukin-12 secretion(GO:2001182)
0.2	0.8	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.6	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2	0.5	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
0.1	0.4	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.6	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.1	4.0	GO:0031648	protein destabilization(GO:0031648)
0.1	0.8	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.1	0.1	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	0.3	GO:0033206	meiotic chromosome movement towards spindle pole(GO:0016344) meiotic cytokinesis(GO:0033206)
0.1	0.5	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.8	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	0.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.5	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	0.4	GO:0006083	acetate metabolic process(GO:0006083)
0.1	4.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.1	0.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.1	0.9	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.4	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.4	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.1	0.4	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1	0.4	GO:0072423	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1	0.2	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1	0.4	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	1.3	GO:0006301	postreplication repair(GO:0006301)
0.1	0.5	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.9	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	1.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.1	0.3	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.7	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1	0.3	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.1	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.1	0.7	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1	0.1	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.5	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	1.9	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.1	0.3	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.3	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.3	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.3	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.2	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.1	0.5	GO:0080154	regulation of fertilization(GO:0080154)
0.1	1.0	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	0.7	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.7	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.8	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.3	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	1.6	GO:0010390	histone monoubiquitination(GO:0010390)
0.1	0.2	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.1	0.3	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.1	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.1	0.3	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.1	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.3	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1	0.1	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.1	1.1	GO:0006544	glycine metabolic process(GO:0006544)
0.1	0.4	GO:0046060	dATP metabolic process(GO:0046060)
0.1	0.6	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.1	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.1	0.6	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.1	0.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.6	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.9	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.1	0.2	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.1	0.5	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.1	0.1	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.6	GO:0010388	cullin deneddylation(GO:0010388)
0.1	0.6	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.5	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.7	GO:0046697	decidualization(GO:0046697)
0.1	0.2	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.1	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.8	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.1	0.1	GO:0035087	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1	0.8	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.1	0.7	GO:0097286	iron ion import(GO:0097286)
0.1	0.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.3	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.1	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	0.5	GO:0048242	epinephrine secretion(GO:0048242)
0.1	0.5	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	1.0	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1	0.2	GO:0000087	mitotic M phase(GO:0000087)
0.1	0.3	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.1	0.4	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.2	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	0.3	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.1	0.1	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.1	0.4	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.1	0.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.2	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	1.4	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.1	0.7	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.1	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1	0.6	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.2	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	0.5	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.1	0.9	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.4	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.1	0.1	GO:2000520	regulation of immunological synapse formation(GO:2000520)
0.1	0.1	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.1	0.9	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.1	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	0.6	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	0.3	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.1	0.3	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.4	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	9.1	GO:0051607	defense response to virus(GO:0051607)
0.1	1.2	GO:0072678	T cell migration(GO:0072678)
0.1	0.1	GO:0001562	response to protozoan(GO:0001562)
0.1	0.2	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.1	0.2	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.1	0.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	0.3	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.2	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.1	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.6	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	1.4	GO:0030261	chromosome condensation(GO:0030261)
0.1	0.3	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1	0.5	GO:0015816	glycine transport(GO:0015816)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.7	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.1	GO:0002086	diaphragm contraction(GO:0002086)
0.0	0.0	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	1.9	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.0	0.1	GO:0035743	CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
0.0	0.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.5	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.5	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	1.4	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.2	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.6	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.0	0.2	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0044838	cell quiescence(GO:0044838)
0.0	0.7	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	1.7	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.2	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	1.0	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.3	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0044854	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.3	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0	1.5	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	2.2	GO:0019882	antigen processing and presentation(GO:0019882)
0.0	0.5	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0009757	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.9	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.8	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.0	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
0.0	0.1	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.1	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.3	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.5	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	1.0	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	1.0	GO:0097194	execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.2	GO:0071435	potassium ion export(GO:0071435)
0.0	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.0	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.2	GO:0032060	bleb assembly(GO:0032060)
0.0	0.9	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0	0.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.0	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.0	0.4	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.3	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.4	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.1	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0009946	proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
0.0	0.0	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.3	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.0	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
0.0	0.2	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.2	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0	0.1	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.5	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0035865	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.6	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0	0.1	GO:0035610	protein deglutamylation(GO:0035608) protein side chain deglutamylation(GO:0035610)
0.0	0.2	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.3	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.1	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.9	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.4	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.1	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.1	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.5	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.1	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.2	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0086016	AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027) AV node cell to bundle of His cell communication(GO:0086067)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0	0.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0	0.0	GO:2000969	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.2	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.0	GO:1903421	regulation of synaptic vesicle recycling(GO:1903421)
0.0	0.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	1.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:1902186	regulation of viral release from host cell(GO:1902186)
0.0	0.3	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.3	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.9	GO:0003014	renal system process(GO:0003014)
0.0	0.0	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0051350	negative regulation of lyase activity(GO:0051350)
0.0	0.1	GO:0023035	CD40 signaling pathway(GO:0023035)
0.0	0.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.7	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.0	0.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.2	GO:0007614	short-term memory(GO:0007614)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.8	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.0	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.1	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.0	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.2	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.0	0.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0006057	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.0	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.5	GO:0007569	cell aging(GO:0007569)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.0	GO:0044531	induction of programmed cell death(GO:0012502) modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) positive regulation of apoptotic process in other organism(GO:0044533) modulation by symbiont of host programmed cell death(GO:0052040) positive regulation by symbiont of host programmed cell death(GO:0052042) modulation by symbiont of host apoptotic process(GO:0052150) positive regulation by symbiont of host apoptotic process(GO:0052151) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.4	GO:0006953	acute-phase response(GO:0006953)
0.0	2.3	GO:0042742	defense response to bacterium(GO:0042742)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.2	GO:0050802	circadian sleep/wake cycle, sleep(GO:0050802)
0.0	0.0	GO:1901679	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.5	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.2	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.7	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.0	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0	0.0	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.0	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.0	GO:0031052	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.0	GO:1901317	regulation of sperm motility(GO:1901317) positive regulation of sperm motility(GO:1902093)
0.0	0.0	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.1	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0060371	response to pyrethroid(GO:0046684) regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.4	GO:0007041	lysosomal transport(GO:0007041)
0.0	0.0	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	0.1	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.0	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
0.0	0.1	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.0	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.1	GO:0070813	hydrogen sulfide metabolic process(GO:0070813)
0.0	0.2	GO:0002437	inflammatory response to antigenic stimulus(GO:0002437)
0.0	0.0	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0	0.0	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:0061526	acetylcholine secretion(GO:0061526)
0.0	0.0	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.0	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.0	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.0	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0061081	positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0045583	cytotoxic T cell differentiation(GO:0045065) regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.0	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:1903077	negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.0	GO:0035927	RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.0	0.1	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.2	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.2	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.0	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.1	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.0	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:0000060	protein import into nucleus, translocation(GO:0000060)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	11.7	GO:0042825	TAP complex(GO:0042825)
2.2	15.3	GO:0042382	paraspeckles(GO:0042382)
2.0	18.1	GO:0020003	symbiont-containing vacuole(GO:0020003)
1.4	5.7	GO:0002079	inner acrosomal membrane(GO:0002079)
1.1	4.2	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.0	3.8	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.9	4.7	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.9	4.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.8	2.4	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.6	1.8	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.6	2.3	GO:0042583	chromaffin granule(GO:0042583)
0.6	1.7	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.6	2.8	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.5	6.8	GO:0030014	CCR4-NOT complex(GO:0030014)
0.4	9.8	GO:0022624	proteasome accessory complex(GO:0022624)
0.4	1.2	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.3	1.7	GO:0061617	MICOS complex(GO:0061617)
0.3	0.6	GO:0031523	Myb complex(GO:0031523)
0.3	1.6	GO:0005638	lamin filament(GO:0005638)
0.3	4.7	GO:0000421	autophagosome membrane(GO:0000421)
0.3	0.8	GO:0043511	inhibin complex(GO:0043511)
0.3	1.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	3.5	GO:0043196	varicosity(GO:0043196)
0.2	6.7	GO:0005776	autophagosome(GO:0005776)
0.2	0.6	GO:0097513	myosin II filament(GO:0097513)
0.2	1.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	3.7	GO:0045120	pronucleus(GO:0045120)
0.2	1.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.2	1.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2	2.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.2	0.5	GO:0031084	BLOC-2 complex(GO:0031084)
0.2	2.6	GO:0031430	M band(GO:0031430)
0.2	2.3	GO:0046930	pore complex(GO:0046930)
0.1	5.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	4.4	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.1	9.1	GO:0016605	PML body(GO:0016605)
0.1	0.8	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	10.7	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	0.1	GO:0097512	cardiac myofibril(GO:0097512)
0.1	2.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.4	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	1.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	1.4	GO:0038201	TOR complex(GO:0038201)
0.1	1.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	1.0	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1	3.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.6	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.8	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	2.0	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	2.2	GO:0000786	nucleosome(GO:0000786)
0.1	0.4	GO:0002081	outer acrosomal membrane(GO:0002081)
0.1	1.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	1.3	GO:0030914	STAGA complex(GO:0030914)
0.1	3.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.5	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.3	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	4.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	1.9	GO:0090544	BAF-type complex(GO:0090544)
0.1	0.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.4	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.1	2.8	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	0.4	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.7	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	4.3	GO:0016363	nuclear matrix(GO:0016363)
0.1	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.1	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.6	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.1	0.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	2.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	0.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	0.2	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.1	2.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	0.2	GO:0000235	astral microtubule(GO:0000235)
0.1	0.2	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	6.1	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	0.6	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.5	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	0.4	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.4	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.4	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	1.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	1.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.2	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	1.9	GO:0000776	kinetochore(GO:0000776)
0.0	1.1	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.3	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	2.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	1.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.7	GO:0005922	connexon complex(GO:0005922)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	1.8	GO:1902554	serine/threonine protein kinase complex(GO:1902554)
0.0	1.5	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.9	GO:0005840	ribosome(GO:0005840)
0.0	0.6	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	4.3	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.4	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	1.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	8.3	GO:0005635	nuclear envelope(GO:0005635)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	1.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.5	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.7	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0044393	microspike(GO:0044393)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.3	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	1.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.7	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	2.5	GO:0005769	early endosome(GO:0005769)
0.0	1.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.7	GO:0005814	centriole(GO:0005814)
0.0	2.8	GO:0005925	focal adhesion(GO:0005925)
0.0	2.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.0	GO:0030689	Noc complex(GO:0030689)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0033202	DNA helicase complex(GO:0033202)
0.0	1.2	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.5	GO:0000922	spindle pole(GO:0000922)
0.0	0.1	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.0	GO:0071439	clathrin complex(GO:0071439)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	1.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.2	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0000795	synaptonemal complex(GO:0000795)
0.0	10.3	GO:0005829	cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.7	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.8	11.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
2.3	9.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
2.1	6.3	GO:0030620	U2 snRNA binding(GO:0030620)
1.8	10.6	GO:0061133	endopeptidase activator activity(GO:0061133)
1.7	5.0	GO:0042296	ISG15 transferase activity(GO:0042296)
1.4	6.9	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.4	6.8	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.8	8.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.8	2.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.7	5.0	GO:0050897	cobalt ion binding(GO:0050897)
0.6	4.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.6	11.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6	5.3	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.6	1.7	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.6	5.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6	11.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.6	3.9	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.5	3.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.5	1.4	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.5	0.9	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.4	1.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4	2.4	GO:0043910	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.4	1.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.4	1.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.4	1.5	GO:0052717	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.4	1.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.4	3.2	GO:0031386	protein tag(GO:0031386)
0.4	6.0	GO:0001848	complement binding(GO:0001848)
0.3	2.4	GO:0046790	virion binding(GO:0046790)
0.3	2.4	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3	10.5	GO:0042605	peptide antigen binding(GO:0042605)
0.3	4.9	GO:0008143	poly(A) binding(GO:0008143)
0.3	1.8	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.3	2.6	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3	1.1	GO:0016151	nickel cation binding(GO:0016151)
0.3	0.8	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.3	2.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.3	1.8	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.3	2.6	GO:0031996	thioesterase binding(GO:0031996)
0.3	0.8	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3	1.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2	0.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.2	2.7	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.2	1.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.2	2.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	1.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.2	0.4	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.2	0.9	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	4.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	1.5	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.2	1.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.2	1.5	GO:0043495	protein anchor(GO:0043495)
0.2	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.2	1.0	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2	0.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	0.8	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	11.5	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2	3.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.2	0.6	GO:0000339	RNA cap binding(GO:0000339)
0.2	1.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.2	5.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.2	0.4	GO:0045340	mercury ion binding(GO:0045340)
0.2	31.4	GO:0003924	GTPase activity(GO:0003924)
0.2	0.5	GO:0030984	kininogen binding(GO:0030984)
0.2	0.5	GO:0031493	nucleosomal histone binding(GO:0031493)
0.2	0.7	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.2	0.5	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.2	4.5	GO:0050699	WW domain binding(GO:0050699)
0.2	0.8	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.2	0.6	GO:0032051	clathrin light chain binding(GO:0032051)
0.2	0.8	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.1	0.6	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	2.9	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	2.0	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.9	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.5	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	2.5	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1	3.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	0.9	GO:0034711	inhibin binding(GO:0034711)
0.1	0.6	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.1	1.1	GO:0070513	death domain binding(GO:0070513)
0.1	0.7	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.3	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	1.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.1	GO:0019210	kinase inhibitor activity(GO:0019210)
0.1	1.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.4	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.1	1.0	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.5	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.3	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	1.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.4	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.6	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	1.0	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.3	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.5	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.1	20.4	GO:0043774	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1	0.7	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.4	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.3	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	0.5	GO:0015288	porin activity(GO:0015288)
0.1	1.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	2.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.9	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1	0.3	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1	0.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.1	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1	0.2	GO:0043199	sulfate binding(GO:0043199)
0.1	0.4	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.4	GO:0004000	adenosine deaminase activity(GO:0004000)
0.1	0.5	GO:0008494	translation activator activity(GO:0008494)
0.1	0.3	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.7	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	4.6	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	0.2	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.1	0.2	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.1	2.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	1.3	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	0.6	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.6	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.6	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	1.0	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	1.0	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	3.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.3	GO:0008430	selenium binding(GO:0008430)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	3.3	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	0.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.3	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	1.0	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	0.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.1	2.6	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	1.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.2	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	3.8	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	0.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.6	GO:0052859	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.2	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	1.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.5	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	6.7	GO:0005525	GTP binding(GO:0005525)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.3	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	1.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.8	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0048030	disaccharide binding(GO:0048030)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.3	GO:0034823	acyl-CoA ligase activity(GO:0003996) succinate-CoA ligase activity(GO:0004774) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.7	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	1.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.9	GO:0015932	nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.0	2.5	GO:0001047	core promoter binding(GO:0001047)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0015168	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0	0.1	GO:0034618	arginine binding(GO:0034618)
0.0	2.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.6	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.6	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0015928	fucosidase activity(GO:0015928)
0.0	1.6	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.0	GO:0030352	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	3.3	GO:0019887	protein kinase regulator activity(GO:0019887)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.4	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.4	GO:0043236	laminin binding(GO:0043236)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.4	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	2.2	GO:0004386	helicase activity(GO:0004386)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	1.2	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
0.0	0.8	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0034869	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0043864	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.9	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.2	GO:0047617	palmitoyl-CoA hydrolase activity(GO:0016290) acyl-CoA hydrolase activity(GO:0047617)
0.0	0.0	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.4	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	1.1	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.0	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.0	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	2.8	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.7	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	8.5	GO:0044822	poly(A) RNA binding(GO:0044822)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.0	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	1.1	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.0	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	15.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	8.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	5.2	PID MYC PATHWAY	C-MYC pathway
0.2	1.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	5.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	3.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2	1.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	2.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	6.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	4.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	3.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	0.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	3.3	PID IFNG PATHWAY	IFN-gamma pathway
0.1	1.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	6.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	2.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	3.0	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	2.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	2.1	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	2.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	2.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	2.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	1.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	0.7	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	2.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	2.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	1.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.0	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	1.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.3	PID E2F PATHWAY	E2F transcription factor network
0.0	0.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.1	PID ATF2 PATHWAY	ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	25.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.8	9.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.6	5.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.6	5.6	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.5	2.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.4	7.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.4	3.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	20.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.4	6.4	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.3	14.9	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.3	1.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.2	3.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	4.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	1.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	6.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.2	4.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	2.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	2.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	7.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.2	0.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	1.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	2.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	5.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	1.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	2.4	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	2.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	4.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.6	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	0.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1	0.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	5.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	2.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	3.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	7.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	1.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	4.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	0.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.5	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	1.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.9	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.6	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.5	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.8	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.8	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	2.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.0	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS

Results for Irf3

Z-value: 2.10

Motif logo

Transcription factors associated with Irf3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Irf3 motif across conditions

Conditions sorted by the z-value of the Irf3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: