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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Irf5_Irf6

Z-value: 1.19

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Transcription factors associated with Irf5_Irf6

Gene Symbol	Gene ID	Gene Info
Irf5 Ensembl NCBI MGI UniProt	ENSMUSG00000029771.6	interferon regulatory factor 5
Irf6 Ensembl NCBI MGI UniProt	ENSMUSG00000026638.9	interferon regulatory factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_29524032_29524212	Irf5	2503	0.166053	0.61	6.2e-07	Click!
chr6_29529159_29529310	Irf5	48	0.955892	0.54	2.4e-05	Click!
chr6_29517238_29517408	Irf5	9302	0.102499	0.51	6.8e-05	Click!
chr6_29524288_29524439	Irf5	2262	0.178959	0.40	2.3e-03	Click!
chr6_29528050_29528201	Irf5	145	0.925018	0.35	8.0e-03	Click!
chr1_193153262_193153458	Irf6	206	0.898627	0.57	6.6e-06	Click!
chr1_193152702_193153255	Irf6	133	0.934552	0.56	8.9e-06	Click!
chr1_193153475_193153651	Irf6	409	0.756837	0.51	8.2e-05	Click!
chr1_193153730_193153897	Irf6	659	0.577156	0.50	8.5e-05	Click!
chr1_193156175_193156326	Irf6	419	0.745927	0.49	1.5e-04	Click!

Activity of the Irf5_Irf6 motif across conditions

Conditions sorted by the z-value of the Irf5_Irf6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_24613351_24614205	6.76	Gm28437	predicted gene 28437	193	0.69
chr11_113014293_113014953	4.44	2610035D17Rik	RIKEN cDNA 2610035D17 gene	158454	0.04
chr16_73647165_73647368	4.16	Gm18168	predicted gene, 18168	43214	0.2
chr19_55643252_55643620	4.02	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	98384	0.08
chr12_40023391_40023561	3.96	Arl4a	ADP-ribosylation factor-like 4A	8992	0.19
chr18_5603185_5603788	3.72	Zeb1	zinc finger E-box binding homeobox 1	258	0.88
chr3_88133282_88133636	3.67	Mef2d	myocyte enhancer factor 2D	8913	0.11
chr15_74930453_74930628	3.47	Gm39556	predicted gene, 39556	1103	0.31
chr11_118401778_118402151	2.84	Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	92	0.96
chr5_30887859_30888698	2.82	Agbl5	ATP/GTP binding protein-like 5	416	0.67
chr15_97825087_97825519	2.82	Hdac7	histone deacetylase 7	6166	0.16
chr15_97060183_97060372	2.76	Slc38a4	solute carrier family 38, member 4	4321	0.32
chr11_86201495_86201833	2.73	Brip1os	BRCA1 interacting protein C-terminal helicase 1, opposite strand	281	0.65
chr1_119290612_119290763	2.66	Gm29456	predicted gene 29456	36146	0.14
chr5_3420545_3420714	2.61	Cdk6	cyclin-dependent kinase 6	50320	0.1
chr8_113635379_113635580	2.54	Mon1b	MON1 homolog B, secretory traffciking associated	108	0.96
chr2_166995521_166996079	2.54	Stau1	staufen double-stranded RNA binding protein 1	303	0.83
chr11_109705801_109705979	2.53	Fam20a	family with sequence similarity 20, member A	16366	0.17
chr11_88999276_88999500	2.52	Trim25	tripartite motif-containing 25	12	0.96
chr5_23894337_23894488	2.49	AC117663.1	solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), pseudogene	17969	0.11
chr14_59365472_59365623	2.46	Phf11d	PHD finger protein 11D	77	0.96
chr15_76119070_76119502	2.45	Eppk1	epiplakin 1	909	0.34
chr19_47311560_47311711	2.44	Sh3pxd2a	SH3 and PX domains 2A	3116	0.23
chr16_21818710_21818992	2.43	Map3k13	mitogen-activated protein kinase kinase kinase 13	7091	0.12
chr2_34249625_34250031	2.40	C79798	expressed sequence C79798	37943	0.16
chr7_110893979_110894323	2.32	Gm16336	predicted gene 16336	10834	0.16
chr6_38551798_38552474	2.25	Luc7l2	LUC7-like 2 (S. cerevisiae)	293	0.87
chr19_11235141_11235292	2.20	Ms4a12	membrane-spanning 4-domains, subfamily A, member 12	2768	0.17
chr3_94953605_94954192	2.17	Rfx5	regulatory factor X, 5 (influences HLA class II expression)	177	0.88
chr4_150787186_150787387	2.11	Gm13049	predicted gene 13049	38447	0.13
chr17_36020770_36020975	2.10	H2-T24	histocompatibility 2, T region locus 24	312	0.69
chr3_94650538_94650690	2.07	Gm10972	predicted gene 10972	7516	0.1
chr10_80932223_80932855	2.05	Gadd45b	growth arrest and DNA-damage-inducible 45 beta	1727	0.2
chr5_99978641_99979012	2.04	Hnrnpd	heterogeneous nuclear ribonucleoprotein D	33	0.75
chr4_136250109_136250260	2.02	Tcea3	transcription elongation factor A (SII), 3	2211	0.24
chr3_96427385_96427558	2.00	Gm24136	predicted gene, 24136	4738	0.06
chr15_101105800_101105951	1.98	Ankrd33	ankyrin repeat domain 33	9880	0.12
chr2_51941940_51942128	1.97	Gm13495	predicted gene 13495	3365	0.21
chr3_97076558_97076742	1.97	4930573H18Rik	RIKEN cDNA 4930573H18 gene	16135	0.15
chr4_63561883_63562216	1.96	Tmem268	transmembrane protein 268	1689	0.24
chr15_103240587_103240738	1.94	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	168	0.86
chr15_58507689_58507895	1.94	Fer1l6	fer-1-like 6 (C. elegans)	2256	0.37
chr1_180403357_180403508	1.91	Gm36933	predicted gene, 36933	26988	0.12
chr3_89458994_89459453	1.90	Pmvk	phosphomevalonate kinase	105	0.93
chr12_75853443_75853594	1.86	Syne2	spectrin repeat containing, nuclear envelope 2	788	0.72
chr13_59820217_59820403	1.83	Tut7	terminal uridylyl transferase 7	2278	0.17
chr11_121517818_121517969	1.83	Zfp750	zinc finger protein 750	1440	0.4
chr9_114730432_114730583	1.83	Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	609	0.7
chr8_107502990_107503291	1.82	Wwp2	WW domain containing E3 ubiquitin protein ligase 2	572	0.75
chr11_83534788_83534966	1.79	Ccl5	chemokine (C-C motif) ligand 5	4359	0.12
chr7_123369807_123370220	1.79	Arhgap17	Rho GTPase activating protein 17	98	0.69
chr1_171503352_171503875	1.77	Alyref2	Aly/REF export factor 2	135	0.7
chr17_34836344_34837687	1.75	Dxo	decapping exoribonuclease	4	0.52
chr6_3399411_3399585	1.75	Samd9l	sterile alpha motif domain containing 9-like	74	0.97
chr2_181241922_181242214	1.70	Helz2	helicase with zinc finger 2, transcriptional coactivator	41	0.95
chr2_162930858_162931274	1.67	Srsf6	serine and arginine-rich splicing factor 6	462	0.73
chr11_101551830_101552448	1.67	Nbr1	NBR1, autophagy cargo receptor	10	0.69
chr2_119594451_119595035	1.66	Oip5os1	Opa interacting protein 5, opposite strand 1	440	0.72
chr9_50667662_50667813	1.65	Dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	7957	0.12
chr18_3509123_3509283	1.64	Bambi	BMP and activin membrane-bound inhibitor	1280	0.39
chr8_35825975_35826580	1.62	Cldn23	claudin 23	282	0.89
chr6_134538920_134539095	1.62	Lrp6	low density lipoprotein receptor-related protein 6	2707	0.28
chr15_81523518_81523718	1.61	Gm5218	predicted gene 5218	24073	0.11
chr3_69469886_69470406	1.60	Ppm1l	protein phosphatase 1 (formerly 2C)-like	27067	0.17
chr16_92475555_92475724	1.58	2410124H12Rik	RIKEN cDNA 2410124H12 gene	3103	0.18
chr6_13607973_13608602	1.58	Tmem168	transmembrane protein 168	187	0.96
chr11_80086905_80087159	1.56	Atad5	ATPase family, AAA domain containing 5	2368	0.24
chr5_115235264_115235764	1.55	Pop5	processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)	322	0.78
chrX_12076868_12077753	1.53	Bcor	BCL6 interacting corepressor	3243	0.34
chr1_64087943_64089121	1.52	Gm13748	predicted gene 13748	9878	0.19
chr13_99018692_99018987	1.50	A930014D07Rik	RIKEN cDNA A930014D07 gene	11740	0.12
chr15_12447052_12447240	1.50	Pdzd2	PDZ domain containing 2	34766	0.17
chr11_106674335_106675138	1.49	Pecam1	platelet/endothelial cell adhesion molecule 1	11410	0.17
chr3_108751572_108751728	1.49	Aknad1	AKNA domain containing 1	876	0.52
chr17_6782057_6782428	1.48	Ezr	ezrin	542	0.73
chr8_111299516_111299699	1.48	Rfwd3	ring finger and WD repeat domain 3	584	0.68
chr1_135244155_135244306	1.44	Gm26642	predicted gene, 26642	4331	0.13
chr6_5263302_5263590	1.43	Pon3	paraoxonase 3	7160	0.17
chr8_46844739_46844892	1.41	Gm45481	predicted gene 45481	10903	0.18
chrX_38473528_38474265	1.40	Gm7598	predicted gene 7598	2565	0.27
chr10_62076266_62076474	1.40	Gm5424	predicted gene 5424	5247	0.19
chr12_103434110_103434336	1.39	Ifi27	interferon, alpha-inducible protein 27	11	0.95
chr14_31669663_31670111	1.39	Hacl1	2-hydroxyacyl-CoA lyase 1	28601	0.12
chr10_111558785_111559040	1.38	4933440J02Rik	RIKEN cDNA 4933440J02 gene	35361	0.11
chrX_73718748_73718906	1.38	Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	2087	0.17
chr5_137345934_137346263	1.36	Ephb4	Eph receptor B4	4011	0.1
chr13_95672502_95672655	1.35	Iqgap2	IQ motif containing GTPase activating protein 2	1059	0.44
chr2_18821861_18822016	1.35	Carlr	cardiac and apoptosis-related long non-coding RNA	20120	0.17
chr1_73805065_73805216	1.34	Gm29183	predicted gene 29183	36777	0.14
chr8_84912786_84913422	1.34	Dnase2a	deoxyribonuclease II alpha	287	0.74
chr6_54972984_54973135	1.34	Nod1	nucleotide-binding oligomerization domain containing 1	447	0.75
chr2_163643384_163643535	1.34	0610039K10Rik	RIKEN cDNA 0610039K10 gene	1391	0.28
chr5_93044795_93044948	1.30	Sowahb	sosondowah ankyrin repeat domain family member B	151	0.94
chr7_141010676_141010885	1.30	Ifitm3	interferon induced transmembrane protein 3	10	0.94
chr17_23679435_23679764	1.29	Cldn6	claudin 6	60	0.9
chr7_6171760_6172680	1.28	Zfp444	zinc finger protein 444	6	0.95
chr2_72286384_72286535	1.28	Map3k20	mitogen-activated protein kinase kinase kinase 20	665	0.7
chr2_90503274_90503452	1.28	4933423P22Rik	RIKEN cDNA 4933423P22 gene	24113	0.16
chr13_23747319_23747470	1.27	H2bc3	H2B clustered histone 3	660	0.24
chr1_134962889_134963040	1.27	Ube2t	ubiquitin-conjugating enzyme E2T	346	0.87
chr1_138617785_138617943	1.26	Nek7	NIMA (never in mitosis gene a)-related expressed kinase 7	1810	0.35
chr12_8351371_8351565	1.26	Gm48071	predicted gene, 48071	14751	0.15
chr12_110601214_110602253	1.26	Gm35558	predicted gene, 35558	230	0.54
chr4_135494313_135495270	1.25	Stpg1	sperm tail PG rich repeat containing 1	1	0.68
chr16_93816332_93816772	1.25	Dop1b	DOP1 leucine zipper like protein B	7118	0.14
chr11_60954284_60954435	1.25	Map2k3	mitogen-activated protein kinase kinase 3	3697	0.18
chr9_114781250_114781522	1.24	Cmtm7	CKLF-like MARVEL transmembrane domain containing 7	446	0.72
chr15_80948123_80948287	1.24	Adsl	adenylosuccinate lyase	285	0.85
chr6_3345986_3346180	1.24	Gm20559	predicted gene, 20559	12	0.96
chr5_114922913_114923574	1.23	Oasl1	2'-5' oligoadenylate synthetase-like 1	3	0.5
chr5_100636931_100637107	1.23	Coq2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	27400	0.12
chr2_167887628_167887813	1.22	Gm14319	predicted gene 14319	29135	0.14
chr13_24246273_24246424	1.21	Carmil1	capping protein regulator and myosin 1 linker 1	5804	0.17
chr17_64622406_64622562	1.19	Man2a1	mannosidase 2, alpha 1	21748	0.23
chr11_49245593_49245837	1.18	Mgat1	mannoside acetylglucosaminyltransferase 1	484	0.71
chr16_17345888_17346201	1.17	Gm24927	predicted gene, 24927	4032	0.14
chr16_8736071_8736286	1.17	Usp7	ubiquitin specific peptidase 7	2164	0.27
chr5_147758193_147758351	1.15	Gm43156	predicted gene 43156	12756	0.19
chr11_102432143_102432294	1.14	Grn	granulin	567	0.58
chr4_141301097_141301289	1.14	Epha2	Eph receptor A2	47	0.95
chr9_108662236_108662629	1.14	Slc25a20	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20	334	0.76
chr17_25015270_25015559	1.14	Cramp1l	cramped chromatin regulator homolog 1	184	0.83
chr7_106529145_106529296	1.13	Gm8995	predicted gene 8995	17549	0.19
chr15_74967736_74967942	1.12	Ly6e	lymphocyte antigen 6 complex, locus E	11284	0.08
chr11_83078101_83078392	1.12	Gm20234	predicted gene, 20234	7000	0.08
chr13_101551260_101551432	1.11	Gm41043	predicted gene, 41043	3194	0.21
chr17_81064633_81064952	1.10	Thumpd2	THUMP domain containing 2	275	0.95
chr5_132466431_132466777	1.09	Auts2	autism susceptibility candidate 2	17244	0.12
chr11_95988194_95988345	1.08	Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	5658	0.1
chr2_178416528_178416815	1.07	Fam217b	family with sequence similarity 217, member B	2089	0.24
chr6_120363672_120363864	1.07	Kdm5a	lysine (K)-specific demethylase 5A	356	0.64
chr8_94183221_94183742	1.06	Gm39228	predicted gene, 39228	192	0.89
chr15_9114227_9114420	1.05	Nadk2	NAD kinase 2, mitochondrial	11335	0.19
chr14_61559937_61560088	1.05	Gm4118	predicted gene 4118	1214	0.3
chr11_72301460_72301663	1.04	Xaf1	XIAP associated factor 1	68	0.95
chr11_101070242_101070609	1.03	Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)	413	0.68
chr11_86593057_86593325	1.02	Vmp1	vacuole membrane protein 1	6197	0.16
chr5_115565413_115565753	1.02	Gcn1	GCN1 activator of EIF2AK4	280	0.82
chr9_42195741_42195945	1.02	4930546K05Rik	RIKEN cDNA 4930546K05 gene	13370	0.19
chr8_25040382_25040533	1.02	Htra4	HtrA serine peptidase 4	1495	0.28
chr14_75837044_75838069	1.01	Gm48931	predicted gene, 48931	3930	0.16
chr3_85887352_85888077	1.01	4933425M03Rik	RIKEN cDNA 4933425M03 gene	23	0.56
chr11_48871235_48871826	1.01	Irgm1	immunity-related GTPase family M member 1	110	0.93
chr4_80895358_80895537	1.00	Lurap1l	leucine rich adaptor protein 1-like	15199	0.24
chr19_58395865_58396080	0.99	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	58494	0.13
chr16_55504891_55505059	0.99	Mir5118	microRNA 5118	10244	0.28
chr5_122762219_122762370	0.99	Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	1571	0.28
chr11_80713830_80713981	0.99	Myo1d	myosin ID	66098	0.11
chr4_115057189_115057563	0.98	Tal1	T cell acute lymphocytic leukemia 1	62	0.97
chr4_150544939_150545172	0.98	Gm13091	predicted gene 13091	23489	0.18
chr16_95708221_95708531	0.98	Ets2	E26 avian leukemia oncogene 2, 3' domain	2037	0.35
chr1_85735550_85735788	0.98	A630001G21Rik	RIKEN cDNA A630001G21 gene	885	0.45
chr17_88064453_88064954	0.98	Fbxo11	F-box protein 11	184	0.95
chr2_91634834_91635130	0.97	F2	coagulation factor II	1413	0.27
chr4_133197802_133198325	0.97	Mir7017	microRNA 7017	2408	0.19
chr9_58658697_58658848	0.97	Rec114	REC114 meiotic recombination protein	520	0.78
chr10_125896179_125896377	0.97	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	69890	0.13
chr7_139363722_139364567	0.96	Inpp5a	inositol polyphosphate-5-phosphatase A	24965	0.19
chr9_110653586_110654769	0.96	Nbeal2	neurobeachin-like 2	16	0.94
chr16_10843863_10844214	0.95	Rmi2	RecQ mediated genome instability 2	8970	0.1
chr11_101582142_101582330	0.95	Tmem106a	transmembrane protein 106A	6	0.94
chr6_137317920_137318078	0.95	Ptpro	protein tyrosine phosphatase, receptor type, O	65534	0.12
chrX_71767997_71768148	0.94	Rpl30-ps10	ribosomal protein L30, pseudogene 10	35616	0.15
chr9_121416224_121416375	0.94	Trak1	trafficking protein, kinesin binding 1	324	0.89
chr3_57294794_57295054	0.94	Tm4sf1	transmembrane 4 superfamily member 1	35	0.98
chr11_100387947_100388277	0.94	Jup	junction plakoglobin	1342	0.22
chr15_66969305_66970311	0.94	Ndrg1	N-myc downstream regulated gene 1	168	0.8
chr11_57962679_57963326	0.93	Gm12249	predicted gene 12249	10132	0.15
chr13_34651459_34651992	0.93	Pxdc1	PX domain containing 1	956	0.37
chr2_165493612_165494390	0.93	Trp53rka	transformation related protein 53 regulating kinase A	677	0.63
chr5_109844927_109845198	0.92	Gm10416	predicted pseudogene 10416	10917	0.17
chr17_86800656_86800807	0.92	Epas1	endothelial PAS domain protein 1	23602	0.15
chr14_74915830_74916012	0.91	Gm10847	predicted gene 10847	10524	0.2
chr19_60889614_60890006	0.91	Grk5	G protein-coupled receptor kinase 5	61	0.97
chr11_51840369_51840521	0.90	Jade2	jade family PHD finger 2	16680	0.16
chr11_86995691_86995992	0.90	Gm22387	predicted gene, 22387	1422	0.33
chr8_106138461_106138664	0.90	1810019D21Rik	RIKEN cDNA 1810019D21 gene	1497	0.23
chr7_96801514_96801665	0.89	Gm15413	predicted gene 15413	40	0.97
chr2_122158402_122158553	0.88	Trim69	tripartite motif-containing 69	2223	0.19
chr1_53823747_53824100	0.88	Hecw2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	17248	0.16
chr11_22871975_22872126	0.88	Gm24917	predicted gene, 24917	3149	0.16
chr13_21975054_21975346	0.88	Pom121l2	POM121 membrane glycoprotein-like 2 (rat)	5994	0.07
chr13_23751776_23751953	0.87	Gm44484	predicted gene, 44484	349	0.37
chr5_149135169_149135434	0.87	Gm42787	predicted gene 42787	6717	0.1
chr4_132329735_132329903	0.87	Trnau1ap	tRNA selenocysteine 1 associated protein 1	281	0.73
chr7_106215296_106215447	0.87	Gvin1	GTPase, very large interferon inducible 1	45	0.98
chr8_31150109_31150428	0.87	Tti2	TELO2 interacting protein 2	47	0.8
chr7_104315472_104315664	0.87	Trim12a	tripartite motif-containing 12A	102	0.84
chr11_78984796_78985130	0.85	Lgals9	lectin, galactose binding, soluble 9	17	0.98
chr14_116946057_116946269	0.85	Gpc6	glypican 6	20227	0.3
chr15_102025510_102025661	0.85	Krt18	keratin 18	2595	0.17
chr13_21907133_21907284	0.84	Gm11279	predicted gene 11279	4052	0.08
chr5_91402727_91403164	0.84	Btc	betacellulin, epidermal growth factor family member	49	0.98
chr12_82935466_82935659	0.83	1700085C21Rik	RIKEN cDNA 1700085C21 gene	3593	0.28
chr4_104824771_104824922	0.83	C8b	complement component 8, beta polypeptide	25638	0.17
chr19_9989798_9990534	0.83	Best1	bestrophin 1	2749	0.15
chr3_97297851_97298537	0.83	Bcl9	B cell CLL/lymphoma 9	277	0.91
chr5_139389682_139390030	0.83	Gpr146	G protein-coupled receptor 146	71	0.95
chr9_14381410_14381616	0.82	Endod1	endonuclease domain containing 1	6	0.96
chr1_161463766_161463992	0.82	Tnfsf18	tumor necrosis factor (ligand) superfamily, member 18	30776	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf5_Irf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0019086	late viral transcription(GO:0019086)
0.6	1.8	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5	2.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.5	1.5	GO:0045472	response to ether(GO:0045472)
0.4	3.3	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.4	1.5	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.4	1.2	GO:1902896	terminal web assembly(GO:1902896)
0.4	1.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.3	1.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.3	1.7	GO:0006167	AMP biosynthetic process(GO:0006167)
0.3	1.0	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3	1.3	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3	0.9	GO:0070889	platelet alpha granule organization(GO:0070889)
0.3	1.8	GO:0035608	protein deglutamylation(GO:0035608)
0.3	0.9	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.3	0.9	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.3	1.4	GO:0009249	protein lipoylation(GO:0009249)
0.3	1.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.3	1.8	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	0.7	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.2	2.0	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.2	0.7	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.2	0.6	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.2	1.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2	1.5	GO:0099515	actin filament-based transport(GO:0099515)
0.2	0.6	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	1.2	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.2	3.8	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.2	0.7	GO:0009597	detection of virus(GO:0009597)
0.2	0.9	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.2	0.5	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.2	0.5	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.2	0.6	GO:0090168	Golgi reassembly(GO:0090168)
0.2	0.5	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.2	0.5	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.2	0.5	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.7	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1	1.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	0.3	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	0.4	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.4	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1	0.4	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	0.9	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.1	0.4	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.1	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1	0.6	GO:0072675	osteoclast fusion(GO:0072675)
0.1	0.4	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.5	GO:0050904	diapedesis(GO:0050904)
0.1	1.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.4	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.1	0.7	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.3	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1	0.3	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.5	GO:0036233	glycine import(GO:0036233)
0.1	0.1	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
0.1	0.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.6	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.8	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.1	1.5	GO:0050779	RNA destabilization(GO:0050779)
0.1	0.9	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.1	0.3	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.3	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.1	0.3	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	0.3	GO:0009629	response to gravity(GO:0009629)
0.1	0.2	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1	0.4	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0070836	caveola assembly(GO:0070836)
0.1	0.3	GO:0097460	ferrous iron import into cell(GO:0097460)
0.1	0.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.4	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.7	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.1	0.7	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	1.1	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.2	GO:0009804	coumarin metabolic process(GO:0009804)
0.1	0.7	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.3	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.1	0.4	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.3	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.1	0.4	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	0.7	GO:0060179	male mating behavior(GO:0060179)
0.1	1.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.1	0.3	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.1	0.3	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.9	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1	0.2	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	0.4	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.3	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	0.2	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1	0.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.1	0.2	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.1	0.2	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.8	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.1	0.4	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.8	GO:0006337	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1	0.5	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.2	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.7	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1	0.1	GO:0043309	regulation of eosinophil degranulation(GO:0043309)
0.1	0.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	1.1	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	0.1	GO:0048294	negative regulation of isotype switching(GO:0045829) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.1	0.5	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.5	GO:0006012	galactose metabolic process(GO:0006012)
0.1	0.2	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.3	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.3	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.1	0.1	GO:0072610	interleukin-12 secretion(GO:0072610)
0.1	0.4	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	0.3	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.4	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.9	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.1	1.9	GO:0035456	response to interferon-beta(GO:0035456)
0.1	0.3	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.4	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.5	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.1	GO:0032439	endosome localization(GO:0032439)
0.1	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.1	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1	0.2	GO:0006768	biotin metabolic process(GO:0006768)
0.1	0.2	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.1	0.1	GO:0044026	DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1	0.4	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.2	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.1	1.4	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.1	0.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.6	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.3	GO:0015879	carnitine transport(GO:0015879)
0.1	1.8	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.6	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.1	0.3	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.0	0.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.1	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.1	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719)
0.0	0.1	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	1.4	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.2	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.3	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.2	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0	0.2	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	1.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.2	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.2	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.3	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
0.0	0.6	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.9	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.0	GO:0033121	regulation of purine nucleotide catabolic process(GO:0033121)
0.0	0.6	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	1.3	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	1.3	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.2	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.2	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.4	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.1	GO:1903011	negative regulation of bone development(GO:1903011)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.2	GO:0048050	post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.1	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.2	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.4	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.7	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.4	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	1.3	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0003284	septum primum development(GO:0003284)
0.0	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.7	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.9	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.4	GO:0009992	cellular water homeostasis(GO:0009992)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.3	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.3	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0022615	protein to membrane docking(GO:0022615)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.6	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.2	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.2	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.0	0.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0	0.2	GO:0097421	liver regeneration(GO:0097421)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135) negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0031627	telomeric loop formation(GO:0031627)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.2	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.3	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0090148	membrane fission(GO:0090148)
0.0	0.1	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154)
0.0	0.8	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.2	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.1	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.3	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.4	GO:0045620	negative regulation of lymphocyte differentiation(GO:0045620)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.3	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.0	0.0	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.8	GO:0033003	regulation of mast cell activation(GO:0033003)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0	0.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.9	GO:0019319	hexose biosynthetic process(GO:0019319)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.6	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.7	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.2	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0097286	iron ion import(GO:0097286)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.0	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.3	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.3	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.1	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.0	0.0	GO:0035384	thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0	0.1	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.0	0.2	GO:0007614	short-term memory(GO:0007614)
0.0	0.7	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.9	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.2	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0	0.2	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.3	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.0	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.3	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.0	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.2	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0	0.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.0	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0097384	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.2	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.1	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.0	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534)
0.0	0.0	GO:0002585	positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
0.0	0.0	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.3	GO:0007099	centriole replication(GO:0007099)
0.0	0.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.0	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.3	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.0	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.0	0.1	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.0	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.0	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.5	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.0	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0042501	serine phosphorylation of STAT3 protein(GO:0033136) serine phosphorylation of STAT protein(GO:0042501)
0.0	0.9	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
0.0	0.0	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.1	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.9	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.0	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.0	GO:0030578	PML body organization(GO:0030578)
0.0	0.0	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.0	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
0.0	0.1	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0	0.0	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.0	GO:0010446	response to alkaline pH(GO:0010446)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:1990845	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0071316	cellular response to nicotine(GO:0071316)
0.0	0.2	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.4	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.0	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.0	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	1.1	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.0	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.0	GO:0035809	regulation of urine volume(GO:0035809)
0.0	0.0	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
0.0	0.1	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.0	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.0	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.0	0.0	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.0	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0015867	ATP transport(GO:0015867)
0.0	0.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.0	GO:0003163	sinoatrial node development(GO:0003163) growth involved in heart morphogenesis(GO:0003241) sinoatrial node cell differentiation(GO:0060921)
0.0	0.2	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.0	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.0	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.0	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.4	GO:0016126	sterol biosynthetic process(GO:0016126)
0.0	0.1	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.3	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.2	GO:0033120	positive regulation of RNA splicing(GO:0033120)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.4	1.1	GO:0044393	microspike(GO:0044393)
0.2	1.0	GO:0061689	tricellular tight junction(GO:0061689)
0.2	0.7	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	0.9	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	1.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.2	0.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	0.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	0.7	GO:0071953	elastic fiber(GO:0071953)
0.2	2.6	GO:0071004	U2-type prespliceosome(GO:0071004)
0.2	0.6	GO:0071203	WASH complex(GO:0071203)
0.1	0.6	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.5	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.8	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.6	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.5	GO:0042825	TAP complex(GO:0042825)
0.1	0.9	GO:0042587	glycogen granule(GO:0042587)
0.1	0.5	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.1	0.7	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.1	0.3	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.3	GO:0043219	lateral loop(GO:0043219)
0.1	0.3	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	2.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.9	GO:0036038	MKS complex(GO:0036038)
0.1	0.3	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	2.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	1.6	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.7	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.3	GO:0001651	dense fibrillar component(GO:0001651)
0.1	1.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.2	GO:0097443	sorting endosome(GO:0097443)
0.1	0.3	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.1	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	2.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	1.3	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	1.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	4.5	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.2	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.6	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.8	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.2	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	2.7	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	1.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.1	GO:0005914	spot adherens junction(GO:0005914)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.9	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.5	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.4	GO:0015030	Cajal body(GO:0015030)
0.0	1.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.3	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.7	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0098576	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.0	1.0	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.6	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.0	GO:1990923	PET complex(GO:1990923)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.2	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.0	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.8	GO:0000776	kinetochore(GO:0000776)
0.0	3.4	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0097433	dense body(GO:0097433)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.3	2.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3	1.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	1.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	0.6	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.2	0.8	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.2	0.5	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2	1.2	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.9	GO:1990226	histone methyltransferase binding(GO:1990226)
0.2	0.5	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2	0.8	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2	0.5	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2	0.5	GO:0070905	serine binding(GO:0070905)
0.2	2.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	1.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	1.0	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.4	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	1.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1	0.5	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	4.0	GO:0070888	E-box binding(GO:0070888)
0.1	1.3	GO:0048185	activin binding(GO:0048185)
0.1	1.6	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.9	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.4	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.4	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.6	GO:0016936	galactoside binding(GO:0016936)
0.1	0.6	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.3	GO:0030519	snoRNP binding(GO:0030519)
0.1	0.6	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.5	GO:0032027	myosin light chain binding(GO:0032027)
0.1	0.7	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	1.0	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.6	GO:0019534	toxin transporter activity(GO:0019534)
0.1	1.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.7	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.1	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.1	0.2	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.4	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.1	1.8	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.4	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.1	0.6	GO:0031386	protein tag(GO:0031386)
0.1	0.8	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.1	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1	2.8	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.2	GO:0034928	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.1	0.3	GO:0050897	cobalt ion binding(GO:0050897)
0.1	2.0	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	1.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.2	GO:0042731	PH domain binding(GO:0042731)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.1	1.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.2	GO:0031711	bradykinin receptor binding(GO:0031711)
0.1	1.9	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1	0.2	GO:0031013	troponin I binding(GO:0031013)
0.1	0.6	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.1	1.0	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.4	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	1.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.6	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.2	GO:1990254	keratin filament binding(GO:1990254)
0.0	1.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	1.5	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	1.8	GO:0000049	tRNA binding(GO:0000049)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.4	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.4	GO:0052835	cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	1.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.7	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.5	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.1	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.4	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	1.0	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.8	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	1.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.2	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.7	GO:0000907	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0004096	catalase activity(GO:0004096)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0034902	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	0.4	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.6	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.0	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.7	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.2	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	5.7	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.3	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	2.6	GO:0005125	cytokine activity(GO:0005125)
0.0	0.3	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	1.2	GO:0016879	ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0	0.9	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.8	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.0	GO:0030619	U1 snRNA binding(GO:0030619)
0.0	0.0	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	1.5	GO:0003729	mRNA binding(GO:0003729)
0.0	0.0	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	1.4	GO:0004386	helicase activity(GO:0004386)
0.0	0.3	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.7	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	3.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	2.7	PID RHOA PATHWAY	RhoA signaling pathway
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	0.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	1.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	2.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	1.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.7	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	2.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.4	PID P73PATHWAY	p73 transcription factor network
0.0	1.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	1.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.6	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.9	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2	1.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	1.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	4.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	1.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	0.2	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.1	1.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	0.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.8	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	1.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	2.0	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	3.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.7	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.0	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.0	0.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.0	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols

Results for Irf5_Irf6

Z-value: 1.19

Motif logo

Transcription factors associated with Irf5_Irf6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Irf5_Irf6 motif across conditions

Conditions sorted by the z-value of the Irf5_Irf6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf5_Irf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: