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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Klf16_Sp8

Z-value: 4.51

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Transcription factors associated with Klf16_Sp8

Gene Symbol	Gene ID	Gene Info
Klf16 Ensembl NCBI MGI UniProt	ENSMUSG00000035397.8	Kruppel-like factor 16
Sp8 Ensembl NCBI MGI UniProt	ENSMUSG00000048562.6	trans-acting transcription factor 8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_80572548_80572876	Klf16	4609	0.085108	-0.80	2.9e-13	Click!
chr10_80569782_80569989	Klf16	7436	0.076517	-0.79	1.2e-12	Click!
chr10_80570071_80570652	Klf16	6960	0.077340	-0.77	3.9e-12	Click!
chr10_80579002_80579213	Klf16	1786	0.152096	-0.76	2.5e-11	Click!
chr10_80573311_80573467	Klf16	3932	0.090084	-0.75	2.9e-11	Click!
chr12_118846303_118846454	Sp8	49	0.980153	0.65	6.2e-08	Click!
chr12_118856282_118856433	Sp8	8771	0.220361	0.63	2.1e-07	Click!
chr12_118842720_118842871	Sp8	3534	0.268546	0.59	1.7e-06	Click!
chr12_118855850_118856001	Sp8	8339	0.221857	0.54	1.8e-05	Click!
chr12_118842893_118843385	Sp8	3190	0.280401	0.54	1.9e-05	Click!

Activity of the Klf16_Sp8 motif across conditions

Conditions sorted by the z-value of the Klf16_Sp8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_61225302_61226760	156.55	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	541	0.67
chr9_124439906_124440949	150.72	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	441	0.79
chr14_14347096_14348750	100.65	Gm48860	predicted gene, 48860	659	0.44
chr12_3236518_3237725	92.05	Rab10os	RAB10, member RAS oncogene family, opposite strand	510	0.74
chr11_4572974_4574056	91.77	Gm11960	predicted gene 11960	9883	0.16
chrY_90739614_90740540	85.36	Mid1-ps1	midline 1, pseudogene 1	12980	0.18
chr2_33130296_33131698	81.27	Garnl3	GTPase activating RANGAP domain-like 3	389	0.84
chr14_14350947_14351733	79.27	Il3ra	interleukin 3 receptor, alpha chain	1719	0.23
chr2_173658978_173659962	55.64	Ppp4r1l-ps	protein phosphatase 4, regulatory subunit 1-like, pseudogene	34	0.8
chr7_29210966_29212124	52.12	Catsperg1	cation channel sperm associated auxiliary subunit gamma 1	50	0.94
chr5_144357735_144358915	49.82	Dmrt1i	Dmrt1 interacting ncRNA	200	0.51
chr14_120830371_120830865	45.62	Gm9391	predicted gene 9391	3460	0.2
chr10_81429712_81431957	44.98	Nfic	nuclear factor I/C	171	0.85
chr19_38054215_38055320	43.66	I830134H01Rik	RIKEN cDNA I830134H01 gene	239	0.48
chr5_121836427_121837736	42.06	Sh2b3	SH2B adaptor protein 3	222	0.86
chr8_70476397_70477967	38.96	Klhl26	kelch-like 26	214	0.86
chr8_125569269_125570645	38.96	Sipa1l2	signal-induced proliferation-associated 1 like 2	149	0.97
chr16_44687184_44688343	38.41	Nepro	nucleolus and neural progenitor protein	36538	0.14
chr9_124422847_124423464	38.01	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	428	0.8
chr6_88841841_88842983	37.34	Abtb1	ankyrin repeat and BTB (POZ) domain containing 1	428	0.42
chr12_108333504_108334768	34.94	Cyp46a1	cytochrome P450, family 46, subfamily a, polypeptide 1	245	0.91
chr7_6729309_6729829	34.76	Peg3	paternally expressed 3	850	0.28
chr14_57525179_57526034	34.00	Il17d	interleukin 17D	829	0.55
chr15_74539884_74540146	32.81	Adgrb1	adhesion G protein-coupled receptor B1	382	0.85
chr5_142701305_142702538	32.68	Slc29a4	solute carrier family 29 (nucleoside transporters), member 4	180	0.95
chr2_3283505_3284761	31.79	Nmt2	N-myristoyltransferase 2	79	0.97
chr16_94526000_94527258	30.62	Vps26c	VPS26 endosomal protein sorting factor C	188	0.94
chr2_73385763_73387080	30.32	Gpr155	G protein-coupled receptor 155	9	0.9
chr13_54788797_54789586	29.96	Tspan17	tetraspanin 17	186	0.91
chr13_12650037_12651101	29.75	Gpr137b-ps	G protein-coupled receptor 137B, pseudogene	181	0.91
chr8_70659324_70660479	29.41	Pgpep1	pyroglutamyl-peptidase I	163	0.89
chr5_144964803_144965606	28.73	Smurf1	SMAD specific E3 ubiquitin protein ligase 1	635	0.65
chr5_109556763_109557843	28.62	Crlf2	cytokine receptor-like factor 2	830	0.53
chr7_19749021_19749968	28.27	Nectin2	nectin cell adhesion molecule 2	39	0.93
chr7_6727792_6729098	28.16	Peg3	paternally expressed 3	1974	0.16
chr5_65106807_65107827	27.91	Klhl5	kelch-like 5	222	0.92
chr19_10413660_10414496	27.80	Syt7	synaptotagmin VII	10060	0.14
chr7_16285532_16286609	27.35	Ccdc9	coiled-coil domain containing 9	45	0.95
chr17_68003632_68004625	26.72	Arhgap28	Rho GTPase activating protein 28	8	0.99
chr8_4677704_4678740	26.60	Gm7461	predicted gene 7461	143	0.62
chr10_70599218_70599723	26.59	Phyhipl	phytanoyl-CoA hydroxylase interacting protein-like	179	0.96
chr7_44310178_44311500	26.57	Shank1	SH3 and multiple ankyrin repeat domains 1	586	0.43
chr7_19094759_19096427	26.49	Six5	sine oculis-related homeobox 5	999	0.28
chr8_46470414_46471778	26.20	Acsl1	acyl-CoA synthetase long-chain family member 1	24	0.97
chr12_112112751_112113467	25.95	Aspg	asparaginase	169	0.92
chr8_122281269_122282287	25.64	Zfpm1	zinc finger protein, multitype 1	363	0.84
chr14_14345884_14346978	25.55	Il3ra	interleukin 3 receptor, alpha chain	1	0.93
chrX_13346707_13347908	25.39	Gm7129	predicted gene 7129	20288	0.14
chr15_84662949_84663667	25.35	Prr5	proline rich 5 (renal)	6312	0.21
chr10_80826008_80827091	25.23	Oaz1	ornithine decarboxylase antizyme 1	107	0.9
chr13_13393240_13394314	25.23	Gpr137b	G protein-coupled receptor 137B	153	0.93
chr1_89069533_89070748	25.21	Sh3bp4	SH3-domain binding protein 4	275	0.91
chr5_109552541_109552889	25.11	Gm8493	predicted gene 8493	1441	0.33
chr11_120721167_120722110	25.00	Rac3	Rac family small GTPase 3	65	0.91
chr1_21078652_21079573	24.70	Tram2	translocating chain-associating membrane protein 2	117	0.93
chr10_80329105_80330083	24.26	Pcsk4	proprotein convertase subtilisin/kexin type 4	96	0.76
chr16_17927727_17929021	24.26	Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	155	0.9
chr14_118812628_118813057	24.18	n-R5s51	nuclear encoded rRNA 5S 51	14189	0.15
chr9_21852119_21853097	24.02	Dock6	dedicator of cytokinesis 6	8	0.96
chr8_70538591_70539987	24.02	Ell	elongation factor RNA polymerase II	168	0.88
chr9_106452968_106454846	23.87	Pcbp4	poly(rC) binding protein 4	8	0.92
chr9_106886021_106887464	23.80	Rbm15b	RNA binding motif protein 15B	686	0.53
chr17_35836572_35837313	23.69	Tubb5	tubulin, beta 5 class I	118	0.89
chr6_114968557_114970098	23.66	Vgll4	vestigial like family member 4	147	0.97
chr5_24685391_24686443	23.62	Nub1	negative regulator of ubiquitin-like proteins 1	70	0.96
chr9_124439329_124439899	23.58	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	1254	0.4
chr13_55487049_55488117	23.26	Dbn1	drebrin 1	50	0.94
chr15_100614796_100615700	23.22	Dazap2	DAZ associated protein 2	101	0.53
chr10_67978939_67980119	23.13	Rtkn2	rhotekin 2	41	0.98
chr2_26444885_26445708	22.98	Sec16a	SEC16 homolog A, endoplasmic reticulum export factor	80	0.82
chr4_101068780_101069771	22.97	Raver2	ribonucleoprotein, PTB-binding 2	204	0.93
chr9_21204509_21205302	22.71	Pde4a	phosphodiesterase 4A, cAMP specific	8200	0.1
chr7_100932502_100932992	22.63	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	640	0.64
chr8_71628994_71630252	22.29	Mir6769b	microRNA 6769b	1483	0.21
chr13_34129793_34130880	22.10	Tubb2b	tubulin, beta 2B class IIB	18	0.96
chr10_79779826_79781202	22.07	Fstl3	follistatin-like 3	67	0.92
chr5_23675895_23676511	22.04	Srpk2	serine/arginine-rich protein specific kinase 2	152	0.84
chr8_4492910_4494136	21.75	Cers4	ceramide synthase 4	2	0.97
chr5_64739416_64740200	21.74	Gm20033	predicted gene, 20033	18051	0.15
chr7_29169567_29170563	21.66	Ggn	gametogenetin	145	0.58
chr5_110107192_110108507	21.23	Gtpbp6	GTP binding protein 6 (putative)	138	0.9
chr12_30372910_30373696	21.11	Sntg2	syntrophin, gamma 2	8	0.98
chr8_120518680_120519145	20.93	Gm26971	predicted gene, 26971	1703	0.26
chr17_13759899_13761731	20.92	Afdn	afadin, adherens junction formation factor	141	0.73
chr8_4679817_4680161	20.91	Gm6410	predicted gene 6410	1527	0.23
chr6_120294093_120295041	20.89	B4galnt3	beta-1,4-N-acetyl-galactosaminyl transferase 3	8	0.98
chr5_33982851_33984205	20.88	Gm1673	predicted gene 1673	6	0.96
chr10_83722468_83723424	20.80	1500009L16Rik	RIKEN cDNA 1500009L16 gene	20	0.98
chr7_84409236_84410328	20.68	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	101	0.96
chr8_88604116_88604818	20.61	Nkd1	naked cuticle 1	21662	0.15
chr8_123514747_123515742	20.50	Dbndd1	dysbindin (dystrobrevin binding protein 1) domain containing 1	146	0.78
chr19_5071354_5072731	20.50	Tmem151a	transmembrane protein 151A	90	0.61
chr2_102451171_102452295	20.46	Fjx1	four jointed box 1	766	0.72
chr2_28446566_28447382	20.36	Ppp1r26	protein phosphatase 1, regulatory subunit 26	108	0.95
chr8_122284023_122284944	20.09	Zfpm1	zinc finger protein, multitype 1	2342	0.24
chr15_89498976_89499718	20.08	Shank3	SH3 and multiple ankyrin repeat domains 3	276	0.79
chr10_80741710_80742767	20.00	Ap3d1	adaptor-related protein complex 3, delta 1 subunit	26	0.95
chr15_58075897_58077232	19.97	Zhx1	zinc fingers and homeoboxes 1	23	0.63
chr4_152138365_152139322	19.91	Espn	espin	2518	0.17
chrX_150812603_150813957	19.84	Maged2	melanoma antigen, family D, 2	126	0.95
chr14_115040506_115042372	19.83	Mir17hg	Mir17 host gene (non-protein coding)	1440	0.19
chr8_12873206_12874084	19.76	Mcf2l	mcf.2 transforming sequence-like	161	0.92
chr1_93176328_93177269	19.64	Crocc2	ciliary rootlet coiled-coil, rootletin family member 2	8073	0.13
chr16_67620882_67621511	19.64	Cadm2	cell adhesion molecule 2	288	0.94
chr7_45784749_45786509	19.59	Lmtk3	lemur tyrosine kinase 3	119	0.87
chr17_46629306_46630520	19.57	Ptk7	PTK7 protein tyrosine kinase 7	409	0.72
chr9_53705535_53706804	19.54	Rab39	RAB39, member RAS oncogene family	63	0.96
chr17_66448520_66450314	19.30	Mtcl1	microtubule crosslinking factor 1	333	0.57
chr15_99771905_99772913	19.18	Cers5	ceramide synthase 5	53	0.94
chr13_99514931_99516063	19.15	Map1b	microtubule-associated protein 1B	1021	0.37
chr2_130397163_130397956	19.14	Cpxm1	carboxypeptidase X 1 (M14 family)	15	0.94
chrX_106485268_106485878	19.09	Fndc3c1	fibronectin type III domain containing 3C1	172	0.95
chr17_85687855_85689066	19.03	Six2	sine oculis-related homeobox 2	186	0.94
chr10_81464661_81465630	19.03	Gm16105	predicted gene 16105	3986	0.08
chr5_129941152_129942065	19.02	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	362	0.76
chr5_37028527_37029187	18.94	Jakmip1	janus kinase and microtubule interacting protein 1	255	0.91
chr10_78747019_78747870	18.87	Gm30400	predicted gene, 30400	285	0.85
chr3_37419062_37420017	18.73	Nudt6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	18	0.84
chr1_72872536_72872832	18.71	Igfbp5	insulin-like growth factor binding protein 5	1591	0.43
chr8_33992574_33993302	18.71	Gm45817	predicted gene 45817	5738	0.17
chr14_14349938_14350878	18.66	Il3ra	interleukin 3 receptor, alpha chain	787	0.48
chr8_70791948_70793334	18.55	Mast3	microtubule associated serine/threonine kinase 3	204	0.83
chr18_12947284_12947832	18.53	Osbpl1a	oxysterol binding protein-like 1A	5717	0.19
chr5_110104232_110105008	18.41	Gtpbp6	GTP binding protein 6 (putative)	715	0.46
chr8_71602133_71603459	18.29	Fam129c	family with sequence similarity 129, member C	445	0.63
chr7_31053000_31053572	18.22	Fxyd1	FXYD domain-containing ion transport regulator 1	164	0.87
chr4_154019719_154020381	18.18	Lrrc47	leucine rich repeat containing 47	411	0.72
chr7_45865731_45866731	18.12	Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	898	0.32
chr14_3332417_3333262	18.08	Gm2956	predicted gene 2956	212	0.91
chr6_122485766_122486276	18.01	Rimklb	ribosomal modification protein rimK-like family member B	418	0.77
chr15_25621948_25622646	17.99	Myo10	myosin X	228	0.93
chr18_24708936_24710320	17.91	Fhod3	formin homology 2 domain containing 3	183	0.62
chr13_51170738_51171698	17.90	Nxnl2	nucleoredoxin-like 2	159	0.95
chr7_73375251_73375992	17.89	Rgma	repulsive guidance molecule family member A	101	0.56
chr2_3117961_3119194	17.73	Fam171a1	family with sequence similarity 171, member A1	108	0.97
chr6_29434887_29435275	17.61	Flnc	filamin C, gamma	1805	0.2
chr5_112239158_112239879	17.51	Miat	myocardial infarction associated transcript (non-protein coding)	10123	0.11
chr2_145674795_145675792	17.51	Rin2	Ras and Rab interactor 2	74	0.98
chr9_21797681_21798988	17.48	Kank2	KN motif and ankyrin repeat domains 2	169	0.91
chr4_91371091_91372260	17.47	Elavl2	ELAV like RNA binding protein 1	281	0.88
chr2_94273064_94274137	17.43	Mir670hg	MIR670 host gene (non-protein coding)	8682	0.15
chr6_72958015_72959038	17.34	Tmsb10	thymosin, beta 10	38	0.97
chr18_74064418_74065509	17.34	Mapk4	mitogen-activated protein kinase 4	34	0.63
chr6_22874878_22875647	17.32	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1	240	0.94
chr8_84990346_84991110	17.31	Hook2	hook microtubule tethering protein 2	86	0.9
chr8_71686115_71686959	17.29	Insl3	insulin-like 3	2677	0.12
chr14_99045440_99046902	17.27	Mzt1	mitotic spindle organizing protein 1	37	0.51
chr2_138256185_138257474	17.25	Btbd3	BTB (POZ) domain containing 3	159	0.98
chr9_122571793_122572853	17.21	9530059O14Rik	RIKEN cDNA 9530059O14 gene	176	0.93
chr18_46311791_46312285	17.20	Ccdc112	coiled-coil domain containing 112	110	0.96
chr11_98959522_98960759	17.15	Rara	retinoic acid receptor, alpha	272	0.84
chr14_6037512_6038662	17.15	Gm8206	predicted gene 8206	122	0.93
chr10_79681206_79682337	17.12	Cdc34	cell division cycle 34	424	0.63
chr5_97111500_97112336	17.01	Paqr3	progestin and adipoQ receptor family member III	322	0.89
chr8_71374903_71376449	16.95	Nr2f6	nuclear receptor subfamily 2, group F, member 6	114	0.92
chr5_112276495_112277340	16.94	Tpst2	protein-tyrosine sulfotransferase 2	210	0.9
chr15_78835129_78836581	16.91	Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	6769	0.09
chr16_18629072_18630255	16.85	Septin5	septin 5	41	0.96
chr16_44632721_44633371	16.81	Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	74149	0.08
chr8_70315603_70316677	16.72	Cers1	ceramide synthase 1	353	0.75
chr7_38106770_38108111	16.70	Ccne1	cyclin E1	62	0.97
chr4_120854573_120855281	16.68	Rims3	regulating synaptic membrane exocytosis 3	108	0.95
chr5_25498778_25500023	16.67	Kmt2c	lysine (K)-specific methyltransferase 2C	617	0.62
chr7_34570196_34571084	16.62	Gm12784	predicted gene 12784	23434	0.15
chr4_119733256_119734302	16.60	Hivep3	human immunodeficiency virus type I enhancer binding protein 3	5	0.98
chr9_122294282_122295077	16.58	Ano10	anoctamin 10	256	0.84
chr2_93187957_93189155	16.56	Trp53i11	transformation related protein 53 inducible protein 11	635	0.76
chr4_145463625_145464359	16.54	Smarca5-ps	SWI/SNF related, matrix associated, actin depenent ragulator of chromatin, subfamily a, member 5, pseudogene	212	0.89
chr17_56626470_56627486	16.40	Lonp1	lon peptidase 1, mitochondrial	91	0.92
chr10_60193469_60194525	16.39	Chst3	carbohydrate sulfotransferase 3	242	0.93
chr14_7314343_7315443	16.35	Gm3739	predicted gene 3739	156	0.94
chr10_77902919_77903521	16.29	Lrrc3	leucine rich repeat containing 3	684	0.44
chr7_35754026_35754910	16.27	Dpy19l3	dpy-19-like 3 (C. elegans)	14	0.98
chr4_118620310_118621356	16.22	Ebna1bp2	EBNA1 binding protein 2	15	0.52
chr4_152273539_152274471	16.22	Gpr153	G protein-coupled receptor 153	227	0.89
chr5_117125754_117126245	16.19	Taok3	TAO kinase 3	302	0.86
chr9_104002273_104002941	16.17	Nphp3	nephronophthisis 3 (adolescent)	47	0.77
chr2_165511107_165511805	16.16	Slc2a10	solute carrier family 2 (facilitated glucose transporter), member 10	2675	0.23
chr11_108910934_108911269	16.16	Axin2	axin 2	9248	0.21
chr17_25433917_25434633	16.15	Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	492	0.69
chr7_25802241_25803073	16.13	Gm45226	predicted gene 45226	7518	0.08
chr15_74487345_74487780	16.03	Adgrb1	adhesion G protein-coupled receptor B1	28633	0.16
chr5_45449714_45450578	16.01	Qdpr	quinoid dihydropteridine reductase	8	0.96
chr15_32244351_32244917	15.91	Snhg18	small nucleolar RNA host gene 18	28	0.68
chr9_48984513_48985876	15.91	Usp28	ubiquitin specific peptidase 28	181	0.94
chr3_121723245_121724172	15.89	F3	coagulation factor III	138	0.7
chr12_3364588_3366025	15.86	Kif3c	kinesin family member 3C	116	0.94
chr5_73647229_73648112	15.84	Gm43799	predicted gene 43799	79	0.55
chr7_139085918_139086752	15.79	Dpysl4	dihydropyrimidinase-like 4	307	0.89
chr6_99666291_99667273	15.72	Eif4e3	eukaryotic translation initiation factor 4E member 3	11	0.49
chr7_45332643_45333917	15.67	Trpm4	transient receptor potential cation channel, subfamily M, member 4	376	0.63
chr14_3948585_3949537	15.64	Gm3095	predicted gene 3095	14486	0.11
chr2_151701768_151703133	15.64	Tmem74b	transmembrane protein 74B	139	0.92
chr14_45388403_45389548	15.56	Gnpnat1	glucosamine-phosphate N-acetyltransferase 1	14	0.96
chr10_81559146_81561402	15.56	Tle5	TLE family member 5, transcriptional modulator	770	0.38
chr11_100355115_100355864	15.55	Hap1	huntingtin-associated protein 1	106	0.91
chr3_153943944_153945147	15.52	Acadm	acyl-Coenzyme A dehydrogenase, medium chain	78	0.95
chr7_6382694_6383817	15.48	Zfp28	zinc finger protein 28	40	0.94
chr7_45361179_45361983	15.47	Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	241	0.77
chr1_3671269_3672324	15.45	Xkr4	X-linked Kx blood group related 4	298	0.89

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf16_Sp8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.2	127.7	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
16.0	48.1	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
14.3	14.3	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
13.4	40.2	GO:0061642	chemoattraction of axon(GO:0061642)
13.3	39.8	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
12.3	36.8	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
11.6	34.8	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
11.3	33.9	GO:0010643	cell communication by chemical coupling(GO:0010643)
11.2	56.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
10.9	32.7	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
10.8	118.5	GO:0071625	vocalization behavior(GO:0071625)
10.7	32.2	GO:0070384	Harderian gland development(GO:0070384)
10.2	61.0	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
10.1	30.3	GO:0030382	sperm mitochondrion organization(GO:0030382)
10.0	30.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
9.8	29.4	GO:0060594	mammary gland specification(GO:0060594)
9.8	39.2	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
9.4	28.2	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
9.0	63.0	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
8.9	26.7	GO:0032289	central nervous system myelin formation(GO:0032289)
8.8	26.5	GO:0021564	vagus nerve development(GO:0021564)
8.8	61.7	GO:0060601	lateral sprouting from an epithelium(GO:0060601)
8.8	26.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
8.8	26.3	GO:0060221	retinal rod cell differentiation(GO:0060221)
8.7	17.3	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
8.6	42.8	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
8.4	33.5	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
8.2	8.2	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
8.2	32.7	GO:0007412	axon target recognition(GO:0007412)
8.2	49.0	GO:1904424	regulation of GTP binding(GO:1904424)
8.2	16.3	GO:0072198	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
8.1	16.2	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
8.1	24.3	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
8.1	24.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
8.0	24.0	GO:0060178	regulation of exocyst localization(GO:0060178)
8.0	39.9	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
7.8	31.3	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
7.8	7.8	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
7.8	38.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
7.7	15.5	GO:0097062	dendritic spine maintenance(GO:0097062)
7.7	15.4	GO:0021586	pons maturation(GO:0021586)
7.7	69.4	GO:0051764	actin crosslink formation(GO:0051764)
7.7	15.3	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
7.6	38.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
7.4	7.4	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
7.3	7.3	GO:0097104	postsynaptic membrane assembly(GO:0097104)
7.3	14.6	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
7.3	21.9	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
7.3	14.5	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
7.1	21.3	GO:0071492	cellular response to UV-A(GO:0071492)
7.0	21.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
7.0	7.0	GO:0060066	oviduct development(GO:0060066)
7.0	14.1	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
7.0	21.0	GO:0061743	motor learning(GO:0061743)
6.9	27.7	GO:0030035	microspike assembly(GO:0030035)
6.9	27.7	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
6.9	20.7	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
6.9	27.6	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
6.9	13.8	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
6.9	20.7	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
6.9	27.5	GO:0060591	chondroblast differentiation(GO:0060591)
6.9	6.9	GO:0007158	neuron cell-cell adhesion(GO:0007158)
6.8	27.4	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
6.8	20.4	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
6.6	19.8	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
6.6	13.2	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
6.6	13.2	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
6.6	19.7	GO:0021563	glossopharyngeal nerve development(GO:0021563)
6.5	6.5	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
6.5	32.5	GO:0035989	tendon development(GO:0035989)
6.4	6.4	GO:0061551	trigeminal ganglion development(GO:0061551)
6.3	95.0	GO:0007413	axonal fasciculation(GO:0007413)
6.3	50.1	GO:0071420	cellular response to histamine(GO:0071420)
6.2	6.2	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
6.2	6.2	GO:0086017	Purkinje myocyte action potential(GO:0086017)
6.2	37.3	GO:0046069	cGMP catabolic process(GO:0046069)
6.2	12.4	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
6.2	6.2	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
6.1	18.3	GO:0045218	zonula adherens maintenance(GO:0045218)
6.1	18.2	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
6.0	18.1	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
6.0	18.1	GO:0033693	neurofilament bundle assembly(GO:0033693)
6.0	42.1	GO:0001778	plasma membrane repair(GO:0001778)
6.0	6.0	GO:1904528	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
6.0	11.9	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
5.9	17.8	GO:1901420	negative regulation of response to alcohol(GO:1901420)
5.9	17.6	GO:1901529	positive regulation of anion channel activity(GO:1901529)
5.9	35.3	GO:0016198	axon choice point recognition(GO:0016198)
5.8	40.5	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
5.8	23.1	GO:0001880	Mullerian duct regression(GO:0001880)
5.7	17.2	GO:0003192	mitral valve formation(GO:0003192)
5.7	5.7	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
5.6	16.9	GO:0061438	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
5.6	5.6	GO:0003195	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
5.5	16.6	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
5.5	33.3	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
5.5	22.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
5.5	5.5	GO:0003415	chondrocyte hypertrophy(GO:0003415)
5.5	5.5	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
5.5	16.4	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
5.4	27.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
5.4	21.5	GO:0014042	positive regulation of neuron maturation(GO:0014042)
5.4	16.2	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
5.3	10.7	GO:0035262	gonad morphogenesis(GO:0035262)
5.3	26.5	GO:0090385	phagosome-lysosome fusion(GO:0090385)
5.2	10.5	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
5.2	31.2	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
5.1	15.4	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
5.1	15.4	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
5.1	25.7	GO:0048852	diencephalon morphogenesis(GO:0048852)
5.1	15.4	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
5.1	20.5	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
5.1	15.4	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
5.1	15.3	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
5.1	20.4	GO:0031581	hemidesmosome assembly(GO:0031581)
5.1	15.2	GO:0044704	single-organism reproductive behavior(GO:0044704)
5.1	30.4	GO:0060484	lung-associated mesenchyme development(GO:0060484)
5.1	40.4	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
5.0	15.1	GO:0072092	ureteric bud invasion(GO:0072092)
5.0	45.3	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
5.0	9.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
5.0	19.8	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
5.0	19.8	GO:1902534	single-organism membrane invagination(GO:1902534)
5.0	19.8	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
5.0	19.8	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
5.0	14.9	GO:0010288	response to lead ion(GO:0010288)
4.9	4.9	GO:2000381	negative regulation of mesoderm development(GO:2000381)
4.9	24.7	GO:0016081	synaptic vesicle docking(GO:0016081)
4.9	9.9	GO:0097091	synaptic vesicle clustering(GO:0097091)
4.9	24.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
4.9	19.6	GO:0023041	neuronal signal transduction(GO:0023041)
4.9	14.6	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
4.9	9.7	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
4.8	19.4	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
4.8	9.7	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
4.8	14.5	GO:0033566	gamma-tubulin complex localization(GO:0033566)
4.8	14.3	GO:0071895	odontoblast differentiation(GO:0071895)
4.8	14.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
4.8	14.3	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
4.7	9.5	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
4.7	18.9	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
4.7	14.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
4.7	4.7	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
4.7	23.3	GO:0006528	asparagine metabolic process(GO:0006528)
4.6	13.9	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
4.6	18.5	GO:0060024	rhythmic synaptic transmission(GO:0060024)
4.6	18.4	GO:0061314	Notch signaling involved in heart development(GO:0061314)
4.6	27.6	GO:0090273	regulation of somatostatin secretion(GO:0090273)
4.6	4.6	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
4.5	9.1	GO:0072162	metanephric mesenchymal cell differentiation(GO:0072162)
4.5	9.1	GO:0046684	response to pyrethroid(GO:0046684)
4.5	13.5	GO:0048865	stem cell fate commitment(GO:0048865)
4.5	9.0	GO:2000019	negative regulation of male gonad development(GO:2000019)
4.5	18.0	GO:0042940	D-amino acid transport(GO:0042940)
4.5	9.0	GO:0071873	response to norepinephrine(GO:0071873)
4.5	31.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
4.5	4.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
4.5	9.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
4.4	13.2	GO:0060279	positive regulation of ovulation(GO:0060279)
4.4	13.1	GO:0060486	Clara cell differentiation(GO:0060486)
4.4	13.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
4.4	17.5	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
4.3	17.4	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
4.3	34.7	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
4.3	4.3	GO:0099612	protein localization to axon(GO:0099612)
4.3	25.8	GO:0042118	endothelial cell activation(GO:0042118)
4.3	8.6	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
4.3	17.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
4.3	8.5	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
4.3	4.3	GO:0048320	axial mesoderm formation(GO:0048320)
4.3	8.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
4.2	8.5	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
4.2	12.7	GO:0060075	regulation of resting membrane potential(GO:0060075)
4.2	4.2	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
4.2	33.7	GO:0042693	muscle cell fate commitment(GO:0042693)
4.2	8.4	GO:1903055	positive regulation of extracellular matrix organization(GO:1903055) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
4.2	37.4	GO:0060068	vagina development(GO:0060068)
4.1	29.0	GO:0099515	actin filament-based transport(GO:0099515)
4.1	12.4	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
4.1	24.5	GO:0048681	negative regulation of axon regeneration(GO:0048681)
4.1	20.3	GO:0035878	nail development(GO:0035878)
4.1	69.0	GO:0001964	startle response(GO:0001964)
4.0	16.1	GO:0060973	cell migration involved in heart development(GO:0060973)
4.0	12.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
4.0	8.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
4.0	8.0	GO:0061205	paramesonephric duct development(GO:0061205)
4.0	12.0	GO:0060468	prevention of polyspermy(GO:0060468)
4.0	12.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
4.0	20.0	GO:2001023	regulation of response to drug(GO:2001023)
4.0	8.0	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
4.0	11.9	GO:0021524	visceral motor neuron differentiation(GO:0021524)
4.0	19.8	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
3.9	23.6	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
3.9	3.9	GO:2000680	regulation of rubidium ion transport(GO:2000680)
3.9	31.2	GO:0021796	cerebral cortex regionalization(GO:0021796)
3.9	15.5	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
3.9	11.6	GO:0045759	negative regulation of action potential(GO:0045759)
3.9	7.7	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
3.8	7.7	GO:0008038	neuron recognition(GO:0008038)
3.8	15.3	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
3.8	11.5	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
3.8	7.6	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
3.8	30.4	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
3.8	15.2	GO:0021764	amygdala development(GO:0021764)
3.8	15.2	GO:0001923	B-1 B cell differentiation(GO:0001923)
3.8	188.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
3.8	11.3	GO:0070634	transepithelial ammonium transport(GO:0070634)
3.8	7.5	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
3.7	11.2	GO:0046103	inosine biosynthetic process(GO:0046103)
3.7	298.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
3.7	7.4	GO:0021570	rhombomere 4 development(GO:0021570)
3.7	7.4	GO:0072174	metanephric tubule formation(GO:0072174)
3.7	3.7	GO:0060384	innervation(GO:0060384)
3.7	11.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
3.7	11.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
3.6	10.9	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
3.6	3.6	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
3.6	10.9	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
3.6	14.5	GO:0046958	nonassociative learning(GO:0046958)
3.6	10.8	GO:0097503	sialylation(GO:0097503)
3.6	7.2	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
3.6	10.7	GO:0032474	otolith morphogenesis(GO:0032474)
3.6	10.7	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
3.6	7.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
3.5	7.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
3.5	3.5	GO:0014820	tonic smooth muscle contraction(GO:0014820)
3.5	3.5	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
3.5	10.5	GO:0002930	trabecular meshwork development(GO:0002930)
3.5	3.5	GO:0071321	response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
3.5	17.4	GO:0035331	negative regulation of hippo signaling(GO:0035331)
3.5	10.4	GO:0086018	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
3.5	3.5	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
3.5	10.4	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
3.5	6.9	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
3.4	20.7	GO:0035881	amacrine cell differentiation(GO:0035881)
3.4	20.7	GO:0070314	G1 to G0 transition(GO:0070314)
3.4	3.4	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
3.4	3.4	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
3.4	20.3	GO:0099625	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
3.4	20.3	GO:0005513	detection of calcium ion(GO:0005513)
3.4	3.4	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
3.4	16.9	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
3.4	10.1	GO:0043307	eosinophil activation(GO:0043307)
3.4	20.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
3.3	3.3	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
3.3	3.3	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
3.3	13.3	GO:0051639	actin filament network formation(GO:0051639)
3.3	6.7	GO:0051385	response to mineralocorticoid(GO:0051385)
3.3	9.9	GO:0048550	negative regulation of pinocytosis(GO:0048550)
3.3	16.5	GO:0015884	folic acid transport(GO:0015884)
3.3	6.6	GO:0021631	optic nerve morphogenesis(GO:0021631)
3.3	3.3	GO:0065001	specification of axis polarity(GO:0065001)
3.3	6.5	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
3.2	9.7	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
3.2	13.0	GO:0006499	N-terminal protein myristoylation(GO:0006499)
3.2	3.2	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
3.2	16.1	GO:0010996	response to auditory stimulus(GO:0010996)
3.2	6.4	GO:0060166	olfactory pit development(GO:0060166)
3.2	9.6	GO:0016080	synaptic vesicle targeting(GO:0016080)
3.2	15.9	GO:0042473	outer ear morphogenesis(GO:0042473)
3.2	3.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
3.2	3.2	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
3.2	3.2	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
3.2	9.5	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
3.2	3.2	GO:0097374	sensory neuron axon guidance(GO:0097374)
3.2	3.2	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
3.2	6.3	GO:0090135	actin filament branching(GO:0090135)
3.2	9.5	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
3.1	40.8	GO:0003416	endochondral bone growth(GO:0003416)
3.1	9.4	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
3.1	6.3	GO:0001922	B-1 B cell homeostasis(GO:0001922)
3.1	18.8	GO:0048251	elastic fiber assembly(GO:0048251)
3.1	6.2	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.1	24.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
3.1	3.1	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
3.1	9.3	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
3.1	6.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
3.1	9.3	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
3.1	9.2	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
3.1	18.4	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
3.1	6.1	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
3.1	6.1	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
3.1	6.1	GO:0021557	oculomotor nerve development(GO:0021557)
3.0	36.6	GO:0048268	clathrin coat assembly(GO:0048268)
3.0	12.2	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
3.0	3.0	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
3.0	6.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
3.0	6.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
3.0	6.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
3.0	38.9	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
3.0	6.0	GO:0003181	atrioventricular valve morphogenesis(GO:0003181)
3.0	8.9	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.9	20.6	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
2.9	11.8	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.9	2.9	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
2.9	5.9	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
2.9	41.0	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
2.9	8.8	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
2.9	11.7	GO:1902307	positive regulation of sodium ion transmembrane transport(GO:1902307)
2.9	8.8	GO:0002051	osteoblast fate commitment(GO:0002051)
2.9	5.8	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
2.9	17.4	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.9	20.3	GO:0021884	forebrain neuron development(GO:0021884)
2.9	11.5	GO:0021871	forebrain regionalization(GO:0021871)
2.9	5.7	GO:0008355	olfactory learning(GO:0008355)
2.9	5.7	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
2.8	2.8	GO:0043985	histone H4-R3 methylation(GO:0043985)
2.8	5.7	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
2.8	5.7	GO:1902267	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
2.8	8.5	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
2.8	11.3	GO:0021854	hypothalamus development(GO:0021854)
2.8	5.7	GO:0048696	collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
2.8	5.6	GO:1902410	mitotic cytokinetic process(GO:1902410)
2.8	5.6	GO:0061037	negative regulation of cartilage development(GO:0061037)
2.8	5.6	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
2.8	58.8	GO:0030224	monocyte differentiation(GO:0030224)
2.8	8.4	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
2.8	8.4	GO:0060347	heart trabecula formation(GO:0060347)
2.8	2.8	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.8	11.1	GO:0030091	protein repair(GO:0030091)
2.8	2.8	GO:0035799	ureter maturation(GO:0035799)
2.8	19.3	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
2.8	2.8	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
2.8	8.3	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.7	5.5	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
2.7	8.2	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
2.7	30.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
2.7	2.7	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
2.7	2.7	GO:0048664	neuron fate determination(GO:0048664)
2.7	2.7	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
2.7	16.1	GO:0048745	smooth muscle tissue development(GO:0048745)
2.7	5.3	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
2.7	16.0	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
2.7	8.0	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
2.7	2.7	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) nephrogenic mesenchyme development(GO:0072076)
2.7	8.0	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
2.7	2.7	GO:0016115	terpenoid catabolic process(GO:0016115)
2.7	23.9	GO:0006020	inositol metabolic process(GO:0006020)
2.7	10.6	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
2.7	10.6	GO:0048484	enteric nervous system development(GO:0048484)
2.6	5.3	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
2.6	5.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
2.6	18.3	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
2.6	7.8	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
2.6	7.8	GO:2000574	regulation of microtubule motor activity(GO:2000574)
2.6	7.8	GO:0060385	axonogenesis involved in innervation(GO:0060385)
2.6	23.3	GO:0042474	middle ear morphogenesis(GO:0042474)
2.6	7.7	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
2.6	18.0	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
2.6	5.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
2.6	2.6	GO:0021978	telencephalon regionalization(GO:0021978)
2.5	22.9	GO:0048663	neuron fate commitment(GO:0048663)
2.5	10.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.5	5.1	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
2.5	15.2	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
2.5	50.6	GO:0008045	motor neuron axon guidance(GO:0008045)
2.5	15.0	GO:0021859	pyramidal neuron differentiation(GO:0021859)
2.5	2.5	GO:0032225	regulation of synaptic transmission, dopaminergic(GO:0032225)
2.5	2.5	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
2.5	22.4	GO:0035428	hexose transmembrane transport(GO:0035428)
2.5	5.0	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
2.5	12.4	GO:1900452	regulation of long term synaptic depression(GO:1900452)
2.5	7.4	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
2.5	9.8	GO:0061339	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
2.4	7.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
2.4	2.4	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
2.4	7.3	GO:1904970	brush border assembly(GO:1904970)
2.4	4.8	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
2.4	9.7	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
2.4	2.4	GO:0090179	planar cell polarity pathway involved in neural tube closure(GO:0090179)
2.4	9.6	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
2.4	4.8	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
2.4	9.5	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
2.4	7.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
2.4	9.5	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
2.4	7.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
2.4	4.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
2.4	4.7	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
2.4	7.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
2.4	7.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
2.4	35.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
2.4	9.4	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
2.3	7.0	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
2.3	2.3	GO:1901017	negative regulation of potassium ion transmembrane transporter activity(GO:1901017)
2.3	28.1	GO:0061462	protein localization to lysosome(GO:0061462)
2.3	4.7	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
2.3	14.0	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
2.3	4.6	GO:0050805	negative regulation of synaptic transmission(GO:0050805)
2.3	7.0	GO:0060437	lung growth(GO:0060437)
2.3	34.8	GO:2001258	negative regulation of cation channel activity(GO:2001258)
2.3	2.3	GO:0090427	activation of meiosis(GO:0090427)
2.3	6.9	GO:0030070	insulin processing(GO:0030070)
2.3	48.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
2.3	4.6	GO:2000821	regulation of grooming behavior(GO:2000821)
2.3	6.9	GO:0043652	engulfment of apoptotic cell(GO:0043652)
2.3	27.4	GO:0016486	peptide hormone processing(GO:0016486)
2.3	4.6	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
2.3	2.3	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
2.3	2.3	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
2.3	2.3	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
2.3	2.3	GO:0060596	mammary placode formation(GO:0060596)
2.3	2.3	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
2.3	2.3	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
2.2	4.5	GO:0007494	midgut development(GO:0007494)
2.2	2.2	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
2.2	4.5	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
2.2	2.2	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
2.2	8.9	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
2.2	24.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
2.2	11.1	GO:0008063	Toll signaling pathway(GO:0008063)
2.2	10.9	GO:0003338	metanephros morphogenesis(GO:0003338)
2.2	2.2	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
2.2	4.3	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
2.2	88.3	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
2.1	2.1	GO:0015819	lysine transport(GO:0015819)
2.1	2.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
2.1	27.7	GO:0021846	cell proliferation in forebrain(GO:0021846)
2.1	6.4	GO:0032252	secretory granule localization(GO:0032252)
2.1	4.3	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
2.1	12.7	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
2.1	6.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
2.1	31.4	GO:0098926	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
2.1	4.2	GO:0010963	regulation of L-arginine import(GO:0010963)
2.1	31.2	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
2.1	6.2	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
2.1	6.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.1	74.3	GO:0019226	transmission of nerve impulse(GO:0019226)
2.1	2.1	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
2.1	2.1	GO:0003150	muscular septum morphogenesis(GO:0003150)
2.1	4.1	GO:0001757	somite specification(GO:0001757)
2.1	4.1	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
2.1	10.3	GO:0048532	anatomical structure arrangement(GO:0048532)
2.1	6.2	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
2.0	8.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
2.0	8.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
2.0	8.1	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
2.0	14.2	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
2.0	12.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.0	6.1	GO:0030421	defecation(GO:0030421)
2.0	18.0	GO:0060997	dendritic spine morphogenesis(GO:0060997)
2.0	4.0	GO:0045054	constitutive secretory pathway(GO:0045054)
2.0	15.9	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
2.0	2.0	GO:0060214	endocardium formation(GO:0060214)
2.0	9.9	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.0	21.7	GO:0001755	neural crest cell migration(GO:0001755)
2.0	3.9	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
2.0	5.9	GO:2000035	regulation of stem cell division(GO:2000035)
2.0	2.0	GO:0032512	regulation of protein phosphatase type 2B activity(GO:0032512)
2.0	2.0	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
1.9	3.9	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
1.9	3.9	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
1.9	1.9	GO:0007621	negative regulation of female receptivity(GO:0007621)
1.9	9.7	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
1.9	1.9	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
1.9	17.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.9	5.8	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
1.9	15.5	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
1.9	17.4	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
1.9	9.7	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
1.9	5.8	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
1.9	5.8	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
1.9	11.5	GO:0044539	long-chain fatty acid import(GO:0044539)
1.9	1.9	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
1.9	1.9	GO:0072205	metanephric collecting duct development(GO:0072205)
1.9	1.9	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.9	5.7	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
1.9	7.6	GO:0019934	cGMP-mediated signaling(GO:0019934)
1.9	3.8	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
1.9	45.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
1.9	3.8	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
1.9	15.0	GO:0007135	meiosis II(GO:0007135)
1.9	3.7	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.9	1.9	GO:0015705	iodide transport(GO:0015705)
1.9	1.9	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.9	3.7	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
1.9	11.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
1.8	9.2	GO:0045217	cell-cell junction maintenance(GO:0045217)
1.8	3.7	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
1.8	9.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.8	1.8	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.8	1.8	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
1.8	19.9	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
1.8	5.4	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
1.8	5.4	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
1.8	16.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
1.8	14.3	GO:0097120	receptor localization to synapse(GO:0097120)
1.8	5.3	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.8	1.8	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
1.8	1.8	GO:0072053	renal inner medulla development(GO:0072053)
1.8	1.8	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
1.8	3.5	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
1.8	17.6	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
1.8	19.4	GO:0003334	keratinocyte development(GO:0003334)
1.8	3.5	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
1.8	8.8	GO:0033604	negative regulation of catecholamine secretion(GO:0033604)
1.7	26.2	GO:0007416	synapse assembly(GO:0007416)
1.7	13.8	GO:0030903	notochord development(GO:0030903)
1.7	5.2	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
1.7	8.6	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
1.7	22.3	GO:0044458	motile cilium assembly(GO:0044458)
1.7	85.5	GO:0097485	neuron projection guidance(GO:0097485)
1.7	5.1	GO:0035137	hindlimb morphogenesis(GO:0035137)
1.7	3.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.7	5.1	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
1.7	6.8	GO:1903012	positive regulation of bone development(GO:1903012)
1.7	11.8	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
1.7	3.4	GO:0006498	N-terminal protein lipidation(GO:0006498)
1.7	10.1	GO:0036158	outer dynein arm assembly(GO:0036158)
1.7	48.8	GO:0050885	neuromuscular process controlling balance(GO:0050885)
1.7	6.7	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
1.7	15.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
1.7	3.3	GO:0042360	vitamin E metabolic process(GO:0042360)
1.7	3.3	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.7	11.7	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
1.7	6.6	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
1.7	6.6	GO:0097084	vascular smooth muscle cell development(GO:0097084)
1.7	5.0	GO:0035810	positive regulation of urine volume(GO:0035810)
1.6	1.6	GO:0021794	thalamus development(GO:0021794)
1.6	13.1	GO:0060081	membrane hyperpolarization(GO:0060081)
1.6	6.6	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
1.6	3.3	GO:0015888	thiamine transport(GO:0015888)
1.6	11.4	GO:0060292	long term synaptic depression(GO:0060292)
1.6	4.9	GO:0002317	plasma cell differentiation(GO:0002317)
1.6	6.5	GO:0051697	protein delipidation(GO:0051697)
1.6	38.6	GO:0046839	phospholipid dephosphorylation(GO:0046839)
1.6	3.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
1.6	3.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
1.6	1.6	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
1.6	3.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
1.6	17.5	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
1.6	1.6	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
1.6	4.8	GO:1901020	negative regulation of calcium ion transmembrane transporter activity(GO:1901020)
1.6	3.2	GO:0061055	myotome development(GO:0061055)
1.6	3.2	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
1.6	15.8	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
1.6	3.2	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
1.6	4.7	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
1.6	12.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
1.5	4.6	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
1.5	4.6	GO:0032836	glomerular basement membrane development(GO:0032836)
1.5	3.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
1.5	3.1	GO:0072578	neurotransmitter-gated ion channel clustering(GO:0072578)
1.5	3.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
1.5	3.1	GO:0061005	cell differentiation involved in kidney development(GO:0061005)
1.5	1.5	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
1.5	6.1	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
1.5	3.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
1.5	10.6	GO:0006108	malate metabolic process(GO:0006108)
1.5	4.5	GO:0002159	desmosome assembly(GO:0002159)
1.5	4.5	GO:0072318	clathrin coat disassembly(GO:0072318)
1.5	3.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
1.5	4.5	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.5	1.5	GO:0035995	detection of muscle stretch(GO:0035995)
1.5	4.5	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
1.5	4.5	GO:0019478	D-amino acid catabolic process(GO:0019478)
1.5	130.5	GO:0071805	potassium ion transmembrane transport(GO:0071805)
1.5	4.4	GO:0006667	sphinganine metabolic process(GO:0006667)
1.5	10.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
1.5	1.5	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
1.5	2.9	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
1.5	7.3	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.5	2.9	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.5	1.5	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
1.4	4.3	GO:0051466	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
1.4	4.3	GO:0060179	male mating behavior(GO:0060179)
1.4	4.3	GO:0031296	B cell costimulation(GO:0031296)
1.4	5.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
1.4	4.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.4	5.8	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
1.4	4.3	GO:0006566	threonine metabolic process(GO:0006566)
1.4	4.3	GO:0006562	proline catabolic process(GO:0006562)
1.4	1.4	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
1.4	4.3	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
1.4	1.4	GO:0001927	exocyst assembly(GO:0001927)
1.4	11.4	GO:0010842	retina layer formation(GO:0010842)
1.4	5.7	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
1.4	2.8	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
1.4	5.6	GO:0031000	response to caffeine(GO:0031000)
1.4	5.6	GO:0061303	cornea development in camera-type eye(GO:0061303)
1.4	1.4	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
1.4	1.4	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.4	5.5	GO:0036159	inner dynein arm assembly(GO:0036159)
1.4	9.6	GO:0031643	positive regulation of myelination(GO:0031643)
1.4	12.2	GO:0042559	folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
1.4	1.4	GO:2001170	positive regulation of fat cell proliferation(GO:0070346) negative regulation of ATP biosynthetic process(GO:2001170)
1.3	4.0	GO:0001504	neurotransmitter uptake(GO:0001504)
1.3	4.0	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
1.3	2.7	GO:0035095	behavioral response to nicotine(GO:0035095)
1.3	1.3	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
1.3	4.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
1.3	10.6	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
1.3	2.6	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
1.3	11.8	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
1.3	2.6	GO:0008292	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.3	13.1	GO:0002329	pre-B cell differentiation(GO:0002329)
1.3	3.9	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.3	5.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
1.3	10.3	GO:0030539	male genitalia development(GO:0030539)
1.3	1.3	GO:0098815	modulation of excitatory postsynaptic potential(GO:0098815)
1.3	1.3	GO:0017085	response to insecticide(GO:0017085)
1.3	1.3	GO:0051938	L-glutamate import(GO:0051938)
1.3	1.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
1.3	5.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.3	2.5	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
1.3	1.3	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
1.3	1.3	GO:0010460	positive regulation of heart rate(GO:0010460)
1.3	1.3	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
1.3	1.3	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.3	1.3	GO:0072008	glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
1.2	1.2	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
1.2	22.4	GO:0015844	monoamine transport(GO:0015844)
1.2	4.9	GO:0007258	JUN phosphorylation(GO:0007258)
1.2	2.5	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
1.2	12.3	GO:2001222	regulation of neuron migration(GO:2001222)
1.2	1.2	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
1.2	3.7	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
1.2	17.1	GO:0006910	phagocytosis, recognition(GO:0006910)
1.2	9.7	GO:0010863	activation of phospholipase C activity(GO:0007202) positive regulation of phospholipase C activity(GO:0010863)
1.2	6.0	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
1.2	6.0	GO:0060914	heart formation(GO:0060914)
1.2	8.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
1.2	1.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
1.2	1.2	GO:0043465	regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
1.2	4.7	GO:0070528	protein kinase C signaling(GO:0070528)
1.2	4.7	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.2	1.2	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
1.2	3.5	GO:0050955	thermoception(GO:0050955)
1.2	1.2	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
1.2	3.5	GO:0006553	lysine metabolic process(GO:0006553)
1.2	3.5	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.2	2.3	GO:0070294	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
1.2	9.2	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
1.2	5.8	GO:0042428	serotonin metabolic process(GO:0042428)
1.2	6.9	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
1.1	5.7	GO:0071236	cellular response to antibiotic(GO:0071236)
1.1	3.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
1.1	10.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
1.1	6.9	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
1.1	2.3	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
1.1	2.3	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
1.1	17.1	GO:0007588	excretion(GO:0007588)
1.1	9.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.1	3.4	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
1.1	2.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.1	4.5	GO:0018158	protein oxidation(GO:0018158)
1.1	2.2	GO:0090399	replicative senescence(GO:0090399)
1.1	13.3	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
1.1	2.2	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.1	2.2	GO:0048014	Tie signaling pathway(GO:0048014)
1.1	2.2	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.1	1.1	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
1.1	1.1	GO:0031620	regulation of fever generation(GO:0031620)
1.1	9.7	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.1	7.6	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
1.1	2.2	GO:0032532	regulation of microvillus length(GO:0032532)
1.1	4.3	GO:0006198	cAMP catabolic process(GO:0006198)
1.1	25.8	GO:0046847	filopodium assembly(GO:0046847)
1.1	2.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
1.1	6.4	GO:2000505	regulation of energy homeostasis(GO:2000505)
1.1	2.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
1.1	2.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.1	9.5	GO:0030575	nuclear body organization(GO:0030575)
1.1	1.1	GO:0048485	sympathetic nervous system development(GO:0048485)
1.1	5.3	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
1.0	4.2	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.0	1.0	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
1.0	11.5	GO:0070208	protein heterotrimerization(GO:0070208)
1.0	6.3	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
1.0	8.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
1.0	4.2	GO:0036315	cellular response to sterol(GO:0036315)
1.0	2.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.0	4.1	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.0	3.1	GO:0010847	regulation of chromatin assembly(GO:0010847)
1.0	4.1	GO:0035641	locomotory exploration behavior(GO:0035641)
1.0	2.1	GO:0046909	intermembrane transport(GO:0046909)
1.0	3.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.0	4.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
1.0	3.1	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
1.0	4.1	GO:0008090	retrograde axonal transport(GO:0008090)
1.0	4.1	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
1.0	1.0	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
1.0	1.0	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
1.0	3.0	GO:0080154	regulation of fertilization(GO:0080154)
1.0	5.0	GO:0046836	glycolipid transport(GO:0046836)
1.0	4.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
1.0	7.0	GO:0006012	galactose metabolic process(GO:0006012)
1.0	6.0	GO:0070327	thyroid hormone transport(GO:0070327)
1.0	10.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
1.0	26.9	GO:0008333	endosome to lysosome transport(GO:0008333)
1.0	3.0	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
1.0	3.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
1.0	1.0	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.0	4.9	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
1.0	2.0	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
1.0	1.0	GO:0060439	trachea morphogenesis(GO:0060439)
1.0	3.9	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.0	20.5	GO:0009268	response to pH(GO:0009268)
1.0	1.9	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.0	5.8	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
1.0	1.9	GO:0060065	uterus development(GO:0060065)
1.0	2.9	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
1.0	2.9	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
1.0	1.0	GO:0048148	behavioral response to cocaine(GO:0048148)
1.0	2.9	GO:0034650	cortisol metabolic process(GO:0034650)
1.0	2.9	GO:0009957	epidermal cell fate specification(GO:0009957)
1.0	7.7	GO:0036342	post-anal tail morphogenesis(GO:0036342)
1.0	2.9	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
1.0	1.9	GO:1903232	melanosome assembly(GO:1903232)
1.0	2.9	GO:0052428	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.0	2.9	GO:0097283	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
1.0	1.0	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
0.9	3.8	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.9	2.8	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.9	1.9	GO:0090383	phagosome acidification(GO:0090383)
0.9	1.9	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.9	10.2	GO:0003009	skeletal muscle contraction(GO:0003009)
0.9	1.9	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.9	2.8	GO:0007220	Notch receptor processing(GO:0007220)
0.9	3.7	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.9	9.2	GO:0008347	glial cell migration(GO:0008347)
0.9	1.8	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.9	6.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.9	0.9	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.9	1.8	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.9	2.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.9	0.9	GO:0051451	myoblast migration(GO:0051451)
0.9	1.8	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
0.9	9.9	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.9	3.6	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.9	9.8	GO:0033622	integrin activation(GO:0033622)
0.9	3.6	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.9	1.8	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.9	2.6	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.9	0.9	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.9	3.5	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.9	1.8	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.9	1.7	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.9	5.2	GO:0034982	mitochondrial protein processing(GO:0034982)
0.9	49.3	GO:0006836	neurotransmitter transport(GO:0006836)
0.9	2.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.9	4.3	GO:0035418	protein localization to synapse(GO:0035418)
0.9	6.0	GO:0006105	succinate metabolic process(GO:0006105)
0.9	23.2	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.9	0.9	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.9	0.9	GO:0044533	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.8	4.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.8	1.7	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.8	0.8	GO:0001710	mesodermal cell fate commitment(GO:0001710)
0.8	0.8	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.8	12.7	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.8	2.5	GO:0060033	anatomical structure regression(GO:0060033)
0.8	7.6	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.8	2.5	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.8	2.5	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.8	4.2	GO:0021885	forebrain cell migration(GO:0021885)
0.8	3.3	GO:1903044	protein transport into membrane raft(GO:0032596) protein localization to membrane raft(GO:1903044)
0.8	1.7	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8	3.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.8	5.0	GO:0045762	positive regulation of adenylate cyclase activity(GO:0045762)
0.8	3.3	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.8	16.5	GO:0007340	acrosome reaction(GO:0007340)
0.8	4.1	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.8	0.8	GO:0048318	axial mesoderm development(GO:0048318)
0.8	1.6	GO:2000870	progesterone secretion(GO:0042701) regulation of progesterone secretion(GO:2000870)
0.8	0.8	GO:0016048	detection of temperature stimulus(GO:0016048)
0.8	5.7	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.8	1.6	GO:0032486	Rap protein signal transduction(GO:0032486)
0.8	2.4	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.8	4.8	GO:0018344	protein geranylgeranylation(GO:0018344)
0.8	2.4	GO:0050807	regulation of synapse organization(GO:0050807)
0.8	2.4	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.8	1.6	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.8	7.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.8	1.6	GO:0014075	response to amine(GO:0014075)
0.8	4.0	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.8	6.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.8	44.2	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.8	2.4	GO:0032835	glomerulus development(GO:0032835)
0.8	4.7	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.8	1.6	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.8	1.6	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.8	3.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.8	2.3	GO:0033762	response to glucagon(GO:0033762)
0.8	10.0	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.8	17.6	GO:0007019	microtubule depolymerization(GO:0007019)
0.8	1.5	GO:0030432	peristalsis(GO:0030432)
0.8	8.4	GO:0036065	fucosylation(GO:0036065)
0.8	0.8	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.8	8.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.8	0.8	GO:2001053	regulation of mesenchymal cell apoptotic process(GO:2001053)
0.7	5.2	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.7	2.2	GO:0035372	protein localization to microtubule(GO:0035372)
0.7	1.5	GO:0030321	transepithelial chloride transport(GO:0030321)
0.7	2.2	GO:0043129	surfactant homeostasis(GO:0043129)
0.7	6.7	GO:0046549	retinal cone cell development(GO:0046549)
0.7	0.7	GO:1903011	negative regulation of bone development(GO:1903011)
0.7	0.7	GO:0061525	hindgut development(GO:0061525)
0.7	1.4	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.7	2.1	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.7	5.7	GO:0007528	neuromuscular junction development(GO:0007528)
0.7	3.5	GO:0048539	bone marrow development(GO:0048539)
0.7	3.5	GO:0014002	astrocyte development(GO:0014002)
0.7	2.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.7	1.4	GO:0042637	catagen(GO:0042637)
0.7	2.8	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.7	2.1	GO:2001212	regulation of vasculogenesis(GO:2001212)
0.7	1.4	GO:0033504	floor plate development(GO:0033504)
0.7	2.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.7	2.0	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.7	2.7	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.7	1.3	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.7	1.3	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.7	0.7	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.7	1.3	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.7	2.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.7	2.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.7	2.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.6	1.9	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.6	0.6	GO:1900107	regulation of nodal signaling pathway(GO:1900107)
0.6	14.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.6	1.3	GO:0007386	compartment pattern specification(GO:0007386)
0.6	1.3	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.6	0.6	GO:0060460	left lung morphogenesis(GO:0060460)
0.6	2.5	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.6	8.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.6	2.5	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.6	4.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.6	2.4	GO:0016584	nucleosome positioning(GO:0016584)
0.6	1.2	GO:0021554	optic nerve development(GO:0021554)
0.6	3.0	GO:0001656	metanephros development(GO:0001656)
0.6	1.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.6	2.9	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.6	0.6	GO:0060278	regulation of ovulation(GO:0060278)
0.6	5.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.6	1.2	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.6	4.6	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.6	0.6	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.6	1.7	GO:0002765	immune response-inhibiting signal transduction(GO:0002765)
0.6	1.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.6	1.2	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.6	5.2	GO:0009409	response to cold(GO:0009409)
0.6	0.6	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.6	8.6	GO:0034587	piRNA metabolic process(GO:0034587)
0.6	0.6	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.6	6.9	GO:0015693	magnesium ion transport(GO:0015693)
0.6	0.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.6	13.2	GO:1902476	chloride transmembrane transport(GO:1902476)
0.6	2.3	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.6	2.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.6	2.2	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.5	0.5	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.5	9.1	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.5	4.8	GO:0045109	intermediate filament organization(GO:0045109)
0.5	9.6	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.5	1.0	GO:0086005	ventricular cardiac muscle cell action potential(GO:0086005)
0.5	1.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.5	1.6	GO:0001955	blood vessel maturation(GO:0001955)
0.5	0.5	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650)
0.5	1.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.5	19.8	GO:0048706	embryonic skeletal system development(GO:0048706)
0.5	0.5	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.5	1.5	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5	2.0	GO:0001709	cell fate determination(GO:0001709)
0.5	0.5	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.5	4.0	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5	3.0	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.5	0.5	GO:2000391	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.5	0.5	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085)
0.5	13.6	GO:0031424	keratinization(GO:0031424)
0.5	0.5	GO:0002034	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.5	0.5	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.5	1.9	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.5	6.8	GO:0044243	multicellular organism catabolic process(GO:0044243)
0.5	8.7	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.5	1.4	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5	2.9	GO:0060736	prostate gland growth(GO:0060736)
0.5	1.9	GO:0001696	gastric acid secretion(GO:0001696)
0.5	1.0	GO:0009414	response to water deprivation(GO:0009414)
0.5	0.5	GO:0018377	protein myristoylation(GO:0018377)
0.5	1.4	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.5	2.8	GO:0015074	DNA integration(GO:0015074)
0.5	1.4	GO:0001502	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.5	0.9	GO:0032482	Rab protein signal transduction(GO:0032482)
0.5	3.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.5	2.3	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5	2.3	GO:0009624	response to nematode(GO:0009624)
0.5	0.5	GO:0060300	regulation of cytokine activity(GO:0060300)
0.5	0.5	GO:0055075	potassium ion homeostasis(GO:0055075)
0.5	0.9	GO:0032026	response to magnesium ion(GO:0032026)
0.5	1.4	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.5	0.5	GO:0006517	protein deglycosylation(GO:0006517)
0.5	6.8	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.4	0.9	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.4	1.8	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.4	0.4	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.4	0.9	GO:0021984	adenohypophysis development(GO:0021984)
0.4	42.6	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.4	1.3	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.4	1.7	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.4	1.3	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4	2.5	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.4	2.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.4	3.3	GO:0006013	mannose metabolic process(GO:0006013)
0.4	2.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4	1.6	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.4	3.3	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.4	6.9	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.4	4.8	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.4	0.8	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.4	1.2	GO:0018879	biphenyl metabolic process(GO:0018879)
0.4	0.8	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4	1.6	GO:0030259	lipid glycosylation(GO:0030259)
0.4	0.4	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.4	4.7	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.4	1.2	GO:0051797	regulation of hair follicle development(GO:0051797)
0.4	0.8	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.4	0.4	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.4	0.4	GO:0048483	autonomic nervous system development(GO:0048483)
0.4	0.8	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4	0.4	GO:0006624	vacuolar protein processing(GO:0006624)
0.4	2.6	GO:0090161	Golgi ribbon formation(GO:0090161)
0.4	0.4	GO:0021756	striatum development(GO:0021756)
0.4	2.2	GO:0046471	phosphatidylglycerol metabolic process(GO:0046471)
0.4	1.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.4	0.4	GO:0002339	B cell selection(GO:0002339)
0.4	5.8	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.4	0.4	GO:0097070	ductus arteriosus closure(GO:0097070)
0.4	1.1	GO:1990928	response to amino acid starvation(GO:1990928)
0.4	1.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4	3.6	GO:0002097	tRNA wobble base modification(GO:0002097)
0.4	8.9	GO:1903845	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.4	9.2	GO:0001764	neuron migration(GO:0001764)
0.4	0.4	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.4	0.4	GO:0021571	rhombomere development(GO:0021546) rhombomere 5 development(GO:0021571)
0.3	1.0	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3	1.7	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3	1.7	GO:0032060	bleb assembly(GO:0032060)
0.3	0.7	GO:1902075	cellular response to salt(GO:1902075)
0.3	0.7	GO:0070459	prolactin secretion(GO:0070459)
0.3	8.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.3	12.7	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.3	0.7	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.3	1.7	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.3	0.3	GO:0070141	response to UV-A(GO:0070141)
0.3	0.3	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3	0.6	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.3	0.3	GO:0060618	nipple development(GO:0060618)
0.3	0.3	GO:0050932	regulation of pigment cell differentiation(GO:0050932)
0.3	0.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.3	0.6	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.3	0.3	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.3	0.6	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.3	0.3	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.3	1.5	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.3	0.6	GO:0071351	response to interleukin-18(GO:0070673) cellular response to interleukin-18(GO:0071351)
0.3	0.3	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.3	0.6	GO:0019042	viral latency(GO:0019042)
0.3	0.9	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3	1.4	GO:0006621	protein retention in ER lumen(GO:0006621)
0.3	7.7	GO:0007566	embryo implantation(GO:0007566)
0.3	0.6	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.3	0.3	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3	0.8	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3	0.3	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.3	0.3	GO:1900368	regulation of RNA interference(GO:1900368)
0.3	1.3	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.3	0.8	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.3	0.8	GO:0009106	lipoate metabolic process(GO:0009106)
0.3	0.5	GO:0060023	soft palate development(GO:0060023)
0.3	0.3	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.2	0.5	GO:0002676	regulation of chronic inflammatory response(GO:0002676)
0.2	0.7	GO:0043312	neutrophil degranulation(GO:0043312)
0.2	1.7	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2	0.5	GO:0010455	positive regulation of cell fate commitment(GO:0010455)
0.2	0.2	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.2	2.8	GO:0042471	ear morphogenesis(GO:0042471)
0.2	0.5	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.2	0.2	GO:0060290	transdifferentiation(GO:0060290)
0.2	2.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.2	2.4	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.2	1.3	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2	0.4	GO:0007320	insemination(GO:0007320)
0.2	1.4	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2	1.6	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.2	0.8	GO:0002578	negative regulation of antigen processing and presentation(GO:0002578)
0.2	0.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.2	0.2	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.2	0.4	GO:0001508	action potential(GO:0001508)
0.2	0.4	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2	0.4	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.2	0.2	GO:0060022	hard palate development(GO:0060022)
0.2	0.2	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.2	0.5	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.2	0.2	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.2	10.7	GO:0050890	cognition(GO:0050890)
0.2	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	0.5	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.3	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.2	6.4	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.2	0.6	GO:0016264	gap junction assembly(GO:0016264)
0.2	2.9	GO:0006270	DNA replication initiation(GO:0006270)
0.2	0.3	GO:0030878	thyroid gland development(GO:0030878)
0.1	0.3	GO:0070587	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1	0.3	GO:0042640	anagen(GO:0042640)
0.1	0.4	GO:0046618	drug export(GO:0046618)
0.1	0.4	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1	0.4	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.1	0.1	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.1	0.5	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.7	GO:0031110	regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1	0.1	GO:0007620	copulation(GO:0007620)
0.1	0.1	GO:0002775	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1	0.4	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.1	2.1	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.1	0.8	GO:0045056	transcytosis(GO:0045056)
0.1	0.2	GO:0042417	dopamine metabolic process(GO:0042417)
0.1	0.3	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	1.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.4	GO:0042246	tissue regeneration(GO:0042246)
0.1	1.3	GO:0006063	uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
0.1	0.3	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	0.4	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.1	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1	0.3	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.1	0.2	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.1	0.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.6	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.5	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.1	0.1	GO:1903208	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	0.1	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.1	4.2	GO:0007601	visual perception(GO:0007601)
0.1	1.4	GO:0034605	cellular response to heat(GO:0034605)
0.1	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	0.5	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.1	0.1	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.2	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	0.6	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.1	0.1	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.1	0.1	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.1	2.4	GO:0050909	sensory perception of taste(GO:0050909)
0.0	0.1	GO:1902572	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0008078	mesodermal cell migration(GO:0008078)
0.0	0.2	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.1	GO:1901317	regulation of sperm motility(GO:1901317)
0.0	1.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.0	GO:0070375	ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.0	0.0	GO:0098739	import across plasma membrane(GO:0098739)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	3.0	GO:0019236	response to pheromone(GO:0019236)
0.0	0.2	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.0	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.0	GO:1900274	regulation of phospholipase C activity(GO:1900274)
0.0	0.0	GO:0038001	paracrine signaling(GO:0038001)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.0	GO:0007632	visual behavior(GO:0007632)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0014891	skeletal muscle atrophy(GO:0014732) striated muscle atrophy(GO:0014891)
0.0	0.0	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.0	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	35.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
7.6	22.9	GO:0043259	laminin-10 complex(GO:0043259)
7.6	45.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
7.5	30.2	GO:0044308	axonal spine(GO:0044308)
7.0	42.2	GO:0005915	zonula adherens(GO:0005915)
6.8	47.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
6.7	20.0	GO:0072534	perineuronal net(GO:0072534)
6.7	20.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
6.6	78.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
6.3	50.7	GO:0043083	synaptic cleft(GO:0043083)
5.9	23.7	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
5.8	52.5	GO:0036128	CatSper complex(GO:0036128)
5.8	52.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
5.5	21.9	GO:0071953	elastic fiber(GO:0071953)
5.4	5.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
5.1	60.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
5.0	55.0	GO:0005641	nuclear envelope lumen(GO:0005641)
4.9	44.1	GO:0043194	axon initial segment(GO:0043194)
4.9	131.7	GO:0048786	presynaptic active zone(GO:0048786)
4.8	87.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
4.8	33.9	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
4.8	14.4	GO:1990812	growth cone filopodium(GO:1990812)
4.7	14.1	GO:0097513	myosin II filament(GO:0097513)
4.6	13.8	GO:0097427	microtubule bundle(GO:0097427)
4.6	64.5	GO:0030673	axolemma(GO:0030673)
4.5	13.6	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
4.4	35.2	GO:0030314	junctional membrane complex(GO:0030314)
4.4	8.7	GO:1990635	proximal dendrite(GO:1990635)
4.4	4.4	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
4.3	17.3	GO:0035363	histone locus body(GO:0035363)
4.2	4.2	GO:0005606	laminin-1 complex(GO:0005606)
4.2	71.4	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
4.2	16.8	GO:0005593	FACIT collagen trimer(GO:0005593)
4.1	24.4	GO:0031258	lamellipodium membrane(GO:0031258)
4.0	140.1	GO:0042734	presynaptic membrane(GO:0042734)
3.9	11.8	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
3.8	19.2	GO:0045098	type III intermediate filament(GO:0045098)
3.7	85.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
3.6	35.6	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
3.5	35.3	GO:0001527	microfibril(GO:0001527)
3.5	59.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
3.5	10.4	GO:0044393	microspike(GO:0044393)
3.3	3.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
3.3	9.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
3.3	181.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
3.2	3.2	GO:0005899	insulin receptor complex(GO:0005899)
3.2	35.0	GO:0030877	beta-catenin destruction complex(GO:0030877)
3.2	44.1	GO:0031045	dense core granule(GO:0031045)
3.2	25.2	GO:0030056	hemidesmosome(GO:0030056)
3.1	9.4	GO:0097543	ciliary inversin compartment(GO:0097543)
3.1	24.5	GO:0042788	polysomal ribosome(GO:0042788)
3.0	9.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
2.9	23.0	GO:0005861	troponin complex(GO:0005861)
2.9	17.3	GO:0016012	sarcoglycan complex(GO:0016012)
2.9	37.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
2.8	84.6	GO:0031941	filamentous actin(GO:0031941)
2.8	11.2	GO:0043219	lateral loop(GO:0043219)
2.8	25.3	GO:0035253	ciliary rootlet(GO:0035253)
2.8	5.6	GO:0043196	varicosity(GO:0043196)
2.8	41.5	GO:0005614	interstitial matrix(GO:0005614)
2.7	8.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
2.7	24.1	GO:0000813	ESCRT I complex(GO:0000813)
2.7	10.7	GO:1990357	terminal web(GO:1990357)
2.7	5.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
2.7	5.3	GO:0005610	laminin-5 complex(GO:0005610)
2.6	7.9	GO:0016342	catenin complex(GO:0016342)
2.6	10.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
2.6	7.8	GO:0008275	gamma-tubulin small complex(GO:0008275)
2.6	10.2	GO:1990696	USH2 complex(GO:1990696)
2.5	22.1	GO:0097542	ciliary tip(GO:0097542)
2.4	2.4	GO:0043256	laminin complex(GO:0043256)
2.4	9.6	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.4	14.3	GO:0001652	granular component(GO:0001652)
2.3	21.1	GO:0032433	filopodium tip(GO:0032433)
2.3	9.3	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
2.3	2.3	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
2.3	20.6	GO:0032590	dendrite membrane(GO:0032590)
2.3	9.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
2.2	11.2	GO:0070695	FHF complex(GO:0070695)
2.2	13.2	GO:0032584	growth cone membrane(GO:0032584)
2.2	17.4	GO:0030061	mitochondrial crista(GO:0030061)
2.2	15.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.1	12.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.1	4.2	GO:0043511	inhibin complex(GO:0043511)
2.1	6.3	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.1	98.6	GO:0030175	filopodium(GO:0030175)
2.1	6.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
2.0	4.1	GO:0044316	cone cell pedicle(GO:0044316)
2.0	16.3	GO:0000137	Golgi cis cisterna(GO:0000137)
2.0	264.5	GO:0045211	postsynaptic membrane(GO:0045211)
2.0	6.0	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
2.0	2.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
1.9	27.3	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.9	3.9	GO:1990907	beta-catenin-TCF complex(GO:1990907)
1.9	17.2	GO:0002116	semaphorin receptor complex(GO:0002116)
1.9	1.9	GO:0070820	tertiary granule(GO:0070820)
1.9	5.7	GO:0071439	clathrin complex(GO:0071439)
1.9	7.5	GO:0045180	basal cortex(GO:0045180)
1.8	1.8	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
1.8	189.8	GO:0060076	excitatory synapse(GO:0060076)
1.8	5.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
1.8	19.9	GO:0044295	axonal growth cone(GO:0044295)
1.8	23.5	GO:0034704	calcium channel complex(GO:0034704)
1.8	470.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
1.8	5.3	GO:0060077	inhibitory synapse(GO:0060077)
1.7	8.6	GO:0071547	piP-body(GO:0071547)
1.7	6.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.7	1.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.7	6.6	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.6	4.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.6	49.7	GO:0005581	collagen trimer(GO:0005581)
1.6	9.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
1.6	4.8	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.6	31.5	GO:0005922	connexon complex(GO:0005922)
1.6	7.9	GO:0031983	vesicle lumen(GO:0031983)
1.6	4.7	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.5	6.1	GO:0043296	apical junction complex(GO:0043296)
1.5	6.0	GO:0071203	WASH complex(GO:0071203)
1.5	8.8	GO:0005859	muscle myosin complex(GO:0005859)
1.5	4.4	GO:0070552	BRISC complex(GO:0070552)
1.5	5.8	GO:0030315	T-tubule(GO:0030315)
1.4	4.3	GO:0005927	muscle tendon junction(GO:0005927)
1.4	87.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
1.4	1.4	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.4	4.3	GO:0005914	spot adherens junction(GO:0005914)
1.4	4.3	GO:0044326	dendritic spine neck(GO:0044326)
1.4	63.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.4	171.1	GO:0031225	anchored component of membrane(GO:0031225)
1.4	5.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
1.4	12.3	GO:0036156	inner dynein arm(GO:0036156)
1.3	4.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.3	3.9	GO:0030478	actin cap(GO:0030478)
1.3	1.3	GO:0097418	neurofibrillary tangle(GO:0097418)
1.2	3.7	GO:0032585	multivesicular body membrane(GO:0032585)
1.2	3.7	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
1.2	2.4	GO:0097441	basilar dendrite(GO:0097441)
1.2	3.6	GO:0033186	CAF-1 complex(GO:0033186)
1.2	7.1	GO:0031143	pseudopodium(GO:0031143)
1.2	3.6	GO:0044611	nuclear pore inner ring(GO:0044611)
1.2	2.3	GO:0042583	chromaffin granule(GO:0042583)
1.2	5.8	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
1.1	3.4	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
1.1	2.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
1.1	12.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
1.1	13.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
1.1	9.6	GO:0043034	costamere(GO:0043034)
1.1	11.6	GO:0005865	striated muscle thin filament(GO:0005865)
1.0	10.4	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
1.0	12.5	GO:0046930	pore complex(GO:0046930)
1.0	4.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
1.0	3.1	GO:0032280	symmetric synapse(GO:0032280)
1.0	32.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
1.0	4.1	GO:0000800	lateral element(GO:0000800)
1.0	19.1	GO:0030057	desmosome(GO:0030057)
1.0	3.0	GO:0034706	sodium channel complex(GO:0034706)
1.0	49.2	GO:0031012	extracellular matrix(GO:0031012)
1.0	25.8	GO:0001917	photoreceptor inner segment(GO:0001917)
1.0	1.0	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.0	2.0	GO:0097342	ripoptosome(GO:0097342)
1.0	14.6	GO:0016328	lateral plasma membrane(GO:0016328)
1.0	1.9	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
1.0	4.8	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
1.0	13.3	GO:0043198	dendritic shaft(GO:0043198)
0.9	2.8	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.9	13.2	GO:0035371	microtubule plus-end(GO:0035371)
0.9	68.7	GO:0005923	bicellular tight junction(GO:0005923)
0.9	27.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.9	5.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.9	4.4	GO:0032133	chromosome passenger complex(GO:0032133)
0.9	4.4	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.8	2.5	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.8	9.7	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.8	8.4	GO:0042555	MCM complex(GO:0042555)
0.8	2.3	GO:0097386	glial cell projection(GO:0097386)
0.7	6.0	GO:0042383	sarcolemma(GO:0042383)
0.7	6.0	GO:0001520	outer dense fiber(GO:0001520)
0.7	11.9	GO:0002080	acrosomal membrane(GO:0002080)
0.7	66.1	GO:0044306	neuron projection terminus(GO:0044306)
0.7	32.1	GO:0030027	lamellipodium(GO:0030027)
0.7	7.2	GO:0031932	TORC2 complex(GO:0031932)
0.7	1.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.7	5.7	GO:0036157	outer dynein arm(GO:0036157)
0.7	2.8	GO:0070545	PeBoW complex(GO:0070545)
0.7	6.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.7	11.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.7	7.4	GO:0035102	PRC1 complex(GO:0035102)
0.7	4.7	GO:0030904	retromer complex(GO:0030904)
0.6	0.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.6	5.8	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.6	3.2	GO:0032426	stereocilium tip(GO:0032426)
0.6	1.9	GO:0097422	tubular endosome(GO:0097422)
0.6	1.3	GO:0060170	ciliary membrane(GO:0060170)
0.6	4.9	GO:0042588	zymogen granule(GO:0042588)
0.6	8.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.6	2.4	GO:0032021	NELF complex(GO:0032021)
0.6	7.9	GO:0000145	exocyst(GO:0000145)
0.6	17.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.6	3.5	GO:0031209	SCAR complex(GO:0031209)
0.6	1.2	GO:0043202	lysosomal lumen(GO:0043202)
0.6	1.1	GO:0005883	neurofilament(GO:0005883)
0.6	12.7	GO:0008180	COP9 signalosome(GO:0008180)
0.5	0.5	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.5	0.5	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.5	101.0	GO:0045202	synapse(GO:0045202)
0.5	0.5	GO:0032839	dendrite cytoplasm(GO:0032839)
0.5	0.5	GO:1990393	3M complex(GO:1990393)
0.5	16.5	GO:0043204	perikaryon(GO:0043204)
0.5	1.9	GO:0042629	mast cell granule(GO:0042629)
0.5	3.8	GO:0031901	early endosome membrane(GO:0031901)
0.5	13.9	GO:0005884	actin filament(GO:0005884)
0.5	4.8	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.5	5.0	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.5	3.6	GO:0097225	sperm midpiece(GO:0097225)
0.5	2.3	GO:0001674	female germ cell nucleus(GO:0001674)
0.5	0.9	GO:0070765	gamma-secretase complex(GO:0070765)
0.5	0.9	GO:0097440	apical dendrite(GO:0097440)
0.4	5.8	GO:0005797	Golgi medial cisterna(GO:0005797)
0.4	6.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4	65.4	GO:0043235	receptor complex(GO:0043235)
0.4	0.8	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.4	1.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.4	1.9	GO:0030991	intraciliary transport particle A(GO:0030991)
0.4	291.8	GO:0005887	integral component of plasma membrane(GO:0005887)
0.4	1.5	GO:0072687	meiotic spindle(GO:0072687)
0.4	1.9	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4	7.4	GO:0016235	aggresome(GO:0016235)
0.4	8.1	GO:0031526	brush border membrane(GO:0031526)
0.4	16.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.4	0.4	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.3	0.7	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3	0.3	GO:0035838	growing cell tip(GO:0035838)
0.3	2.3	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.3	8.9	GO:0045335	phagocytic vesicle(GO:0045335)
0.3	1.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3	5.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.3	1.3	GO:0097546	ciliary base(GO:0097546)
0.3	3.4	GO:0000930	gamma-tubulin complex(GO:0000930)
0.3	0.3	GO:0044453	nuclear membrane part(GO:0044453)
0.3	1.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.3	0.9	GO:0042581	specific granule(GO:0042581)
0.3	14.9	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3	5.6	GO:0032587	ruffle membrane(GO:0032587)
0.3	5.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.3	1.9	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3	0.5	GO:0000802	transverse filament(GO:0000802)
0.3	1.5	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.3	1.8	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.3	8.6	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.3	1.0	GO:0035339	SPOTS complex(GO:0035339)
0.2	2.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2	19.9	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2	1.1	GO:0005921	gap junction(GO:0005921)
0.2	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.2	6.7	GO:0045095	keratin filament(GO:0045095)
0.2	1.0	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2	0.6	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.2	0.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2	0.5	GO:0034457	Mpp10 complex(GO:0034457)
0.2	0.2	GO:0045277	respiratory chain complex IV(GO:0045277)
0.2	0.7	GO:0097452	GAIT complex(GO:0097452)
0.2	0.5	GO:0071817	MMXD complex(GO:0071817)
0.2	537.6	GO:0016021	integral component of membrane(GO:0016021)
0.2	1.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.9	GO:0031430	M band(GO:0031430)
0.1	0.7	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.3	GO:0071942	XPC complex(GO:0071942)
0.1	0.4	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	1.6	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.4	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.4	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.1	0.4	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	3.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	2.6	GO:0001533	cornified envelope(GO:0001533)
0.1	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	0.5	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.2	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	0.5	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.0	47.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
15.4	46.3	GO:0097109	neuroligin family protein binding(GO:0097109)
11.9	154.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
11.7	35.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
11.5	34.6	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
11.0	55.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
10.9	21.7	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
9.9	59.7	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
9.8	29.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
8.9	26.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
8.8	26.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
8.6	17.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
7.9	63.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
7.7	23.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
7.1	35.5	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
7.1	85.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
7.1	21.2	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
7.0	49.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
6.9	20.7	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
6.9	20.7	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
6.6	26.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
6.4	25.7	GO:0038064	collagen receptor activity(GO:0038064)
6.4	6.4	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
6.1	30.5	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
6.1	6.1	GO:0031014	troponin T binding(GO:0031014)
5.9	17.8	GO:0035939	microsatellite binding(GO:0035939)
5.6	28.1	GO:0048495	Roundabout binding(GO:0048495)
5.6	27.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.6	38.9	GO:0003680	AT DNA binding(GO:0003680)
5.5	38.4	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
5.4	27.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
5.4	49.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
5.3	68.9	GO:0031005	filamin binding(GO:0031005)
5.2	15.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
5.2	26.0	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
5.2	15.6	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
5.1	15.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
5.1	20.2	GO:0005042	netrin receptor activity(GO:0005042)
5.0	55.0	GO:0005522	profilin binding(GO:0005522)
4.9	88.5	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
4.8	14.3	GO:0008307	structural constituent of muscle(GO:0008307)
4.7	14.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
4.7	18.9	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
4.7	9.4	GO:0045503	dynein light chain binding(GO:0045503)
4.7	47.1	GO:0070411	I-SMAD binding(GO:0070411)
4.7	14.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
4.7	28.0	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
4.6	13.9	GO:0016882	cyclo-ligase activity(GO:0016882)
4.6	22.8	GO:0070051	fibrinogen binding(GO:0070051)
4.5	13.6	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
4.5	81.6	GO:0004890	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
4.5	31.3	GO:0043208	glycosphingolipid binding(GO:0043208)
4.5	13.4	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
4.5	17.8	GO:0032051	clathrin light chain binding(GO:0032051)
4.4	4.4	GO:0008179	adenylate cyclase binding(GO:0008179)
4.4	30.9	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
4.4	21.8	GO:0003708	retinoic acid receptor activity(GO:0003708)
4.3	17.3	GO:0098821	BMP receptor activity(GO:0098821)
4.3	29.9	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
4.2	12.7	GO:0070052	collagen V binding(GO:0070052)
4.2	29.6	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
4.1	36.7	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
4.1	16.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
4.0	20.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
4.0	20.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
4.0	32.1	GO:0001972	retinoic acid binding(GO:0001972)
4.0	119.0	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
3.9	35.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
3.9	11.7	GO:0031708	endothelin B receptor binding(GO:0031708)
3.9	11.6	GO:0051373	FATZ binding(GO:0051373)
3.8	19.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
3.8	19.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
3.8	11.5	GO:1990430	extracellular matrix protein binding(GO:1990430)
3.8	15.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
3.7	11.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.7	14.9	GO:0034056	estrogen response element binding(GO:0034056)
3.7	11.2	GO:0042731	PH domain binding(GO:0042731)
3.7	11.0	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
3.7	55.1	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
3.7	87.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
3.7	25.6	GO:1990459	transferrin receptor binding(GO:1990459)
3.6	3.6	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
3.6	18.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
3.6	14.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
3.6	14.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
3.6	3.6	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
3.5	113.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
3.5	10.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
3.5	34.9	GO:0042577	lipid phosphatase activity(GO:0042577)
3.5	10.4	GO:0031749	D2 dopamine receptor binding(GO:0031749)
3.5	13.8	GO:0004985	opioid receptor activity(GO:0004985)
3.4	13.7	GO:0038132	neuregulin binding(GO:0038132)
3.3	26.5	GO:0048185	activin binding(GO:0048185)
3.3	16.6	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
3.3	43.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
3.3	89.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
3.3	9.8	GO:0030172	troponin C binding(GO:0030172)
3.3	6.5	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
3.3	6.5	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
3.2	31.6	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
3.1	28.2	GO:0032036	myosin heavy chain binding(GO:0032036)
3.1	18.6	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
3.1	58.1	GO:0003785	actin monomer binding(GO:0003785)
3.0	6.1	GO:0031711	bradykinin receptor binding(GO:0031711)
3.0	9.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
3.0	6.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
3.0	9.0	GO:0030284	estrogen receptor activity(GO:0030284)
3.0	11.9	GO:0031750	D3 dopamine receptor binding(GO:0031750)
2.9	111.7	GO:0005109	frizzled binding(GO:0005109)
2.9	35.2	GO:0032794	GTPase activating protein binding(GO:0032794)
2.9	11.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.9	23.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.9	8.6	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
2.9	14.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
2.8	5.7	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
2.8	36.8	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
2.8	11.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
2.8	28.1	GO:0050811	GABA receptor binding(GO:0050811)
2.8	16.9	GO:0008517	folic acid transporter activity(GO:0008517)
2.8	14.0	GO:1990254	keratin filament binding(GO:1990254)
2.8	36.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
2.7	32.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
2.7	10.6	GO:0034711	inhibin binding(GO:0034711)
2.6	26.4	GO:0070700	BMP receptor binding(GO:0070700)
2.6	7.9	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
2.6	207.7	GO:0019955	cytokine binding(GO:0019955)
2.6	10.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
2.6	7.7	GO:0034190	apolipoprotein receptor binding(GO:0034190)
2.6	7.7	GO:0033142	progesterone receptor binding(GO:0033142)
2.6	69.2	GO:0001540	beta-amyloid binding(GO:0001540)
2.5	142.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.5	2.5	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
2.5	5.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
2.5	5.0	GO:0008046	axon guidance receptor activity(GO:0008046)
2.5	7.5	GO:0097108	hedgehog family protein binding(GO:0097108)
2.5	12.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.5	5.0	GO:0044548	S100 protein binding(GO:0044548)
2.5	44.5	GO:0005112	Notch binding(GO:0005112)
2.5	7.4	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
2.5	46.7	GO:0017075	syntaxin-1 binding(GO:0017075)
2.4	7.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
2.4	7.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.4	47.8	GO:0046875	ephrin receptor binding(GO:0046875)
2.3	7.0	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.3	11.5	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
2.3	6.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.3	11.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
2.3	62.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
2.3	13.7	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.3	2.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
2.3	9.1	GO:1904288	BAT3 complex binding(GO:1904288)
2.3	20.4	GO:0038191	neuropilin binding(GO:0038191)
2.3	4.5	GO:0048763	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
2.3	11.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
2.3	18.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
2.2	4.4	GO:0045340	mercury ion binding(GO:0045340)
2.2	31.1	GO:0005243	gap junction channel activity(GO:0005243)
2.2	45.7	GO:0017147	Wnt-protein binding(GO:0017147)
2.1	4.3	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
2.1	8.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
2.1	20.8	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
2.1	16.4	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
2.0	16.4	GO:0015026	coreceptor activity(GO:0015026)
2.0	12.3	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
2.0	8.1	GO:0004969	histamine receptor activity(GO:0004969)
2.0	14.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
2.0	6.0	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
2.0	10.0	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
2.0	6.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
2.0	37.5	GO:0071837	HMG box domain binding(GO:0071837)
1.9	5.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
1.9	17.2	GO:0017154	semaphorin receptor activity(GO:0017154)
1.9	81.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
1.9	7.6	GO:0017089	glycolipid transporter activity(GO:0017089)
1.9	22.5	GO:0030955	potassium ion binding(GO:0030955)
1.9	11.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
1.8	12.9	GO:0033691	sialic acid binding(GO:0033691)
1.8	7.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
1.8	3.7	GO:0097016	L27 domain binding(GO:0097016)
1.8	9.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
1.8	7.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
1.8	5.3	GO:0030158	protein xylosyltransferase activity(GO:0030158)
1.8	7.1	GO:0008502	melatonin receptor activity(GO:0008502)
1.7	8.7	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
1.7	17.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
1.7	7.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.7	5.2	GO:0004995	tachykinin receptor activity(GO:0004995)
1.7	39.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.7	6.9	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.7	8.5	GO:0004111	creatine kinase activity(GO:0004111)
1.7	8.4	GO:0001601	peptide YY receptor activity(GO:0001601)
1.7	11.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
1.7	53.2	GO:0015459	potassium channel regulator activity(GO:0015459)
1.7	8.3	GO:0004565	beta-galactosidase activity(GO:0004565)
1.6	4.9	GO:0042296	ISG15 transferase activity(GO:0042296)
1.6	22.8	GO:0001968	fibronectin binding(GO:0001968)
1.6	32.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
1.6	14.4	GO:0045294	alpha-catenin binding(GO:0045294)
1.6	3.2	GO:0048019	receptor antagonist activity(GO:0048019)
1.6	3.2	GO:0005523	tropomyosin binding(GO:0005523)
1.5	9.3	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
1.5	7.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
1.5	18.4	GO:0034185	apolipoprotein binding(GO:0034185)
1.5	19.9	GO:0017134	fibroblast growth factor binding(GO:0017134)
1.5	24.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
1.5	7.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
1.5	18.2	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796)
1.5	10.6	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
1.5	1.5	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.5	36.4	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
1.5	4.4	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
1.4	12.9	GO:0030553	cGMP binding(GO:0030553)
1.4	53.6	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
1.4	2.8	GO:0070840	dynein complex binding(GO:0070840)
1.4	19.6	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
1.4	5.6	GO:0030506	ankyrin binding(GO:0030506)
1.4	5.6	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
1.4	1.4	GO:0004517	nitric-oxide synthase activity(GO:0004517)
1.4	20.6	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
1.4	4.1	GO:0008142	oxysterol binding(GO:0008142)
1.4	15.1	GO:0005272	sodium channel activity(GO:0005272)
1.4	4.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.3	2.7	GO:0051380	norepinephrine binding(GO:0051380)
1.3	5.4	GO:0017166	vinculin binding(GO:0017166)
1.3	5.4	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
1.3	5.3	GO:0046923	ER retention sequence binding(GO:0046923)
1.3	16.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
1.3	9.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
1.3	12.0	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.3	6.6	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.3	14.5	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
1.3	11.8	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
1.3	2.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
1.3	7.8	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.3	6.4	GO:0005499	vitamin D binding(GO:0005499)
1.3	3.8	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.3	84.0	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
1.3	3.8	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
1.3	26.4	GO:0042805	actinin binding(GO:0042805)
1.3	2.5	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
1.3	1.3	GO:0019187	beta-1,4-mannosyltransferase activity(GO:0019187)
1.2	1.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.2	9.9	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
1.2	3.7	GO:2001069	glycogen binding(GO:2001069)
1.2	7.3	GO:0008301	DNA binding, bending(GO:0008301)
1.2	2.4	GO:0042289	MHC class II protein binding(GO:0042289)
1.2	7.3	GO:0070097	delta-catenin binding(GO:0070097)
1.2	4.8	GO:0033130	acetylcholine receptor binding(GO:0033130)
1.2	272.7	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.2	12.9	GO:0048038	quinone binding(GO:0048038)
1.2	7.0	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.2	7.0	GO:0002151	G-quadruplex RNA binding(GO:0002151)
1.2	8.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
1.2	11.5	GO:0043274	phospholipase binding(GO:0043274)
1.1	4.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.1	12.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
1.1	2.3	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
1.1	8.0	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.1	93.5	GO:0008201	heparin binding(GO:0008201)
1.1	11.4	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.1	4.5	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.1	2.3	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
1.1	44.9	GO:0017022	myosin binding(GO:0017022)
1.1	10.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
1.1	28.9	GO:0005539	glycosaminoglycan binding(GO:0005539)
1.1	7.8	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
1.1	4.4	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.1	6.6	GO:0031432	titin binding(GO:0031432)
1.1	3.3	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
1.1	13.1	GO:0045499	chemorepellent activity(GO:0045499)
1.1	2.2	GO:0004948	calcitonin receptor activity(GO:0004948)
1.1	11.9	GO:0015643	toxic substance binding(GO:0015643)
1.1	6.5	GO:0045295	gamma-catenin binding(GO:0045295)
1.1	4.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.1	10.7	GO:0001784	phosphotyrosine binding(GO:0001784)
1.1	11.7	GO:0008146	sulfotransferase activity(GO:0008146)
1.1	14.9	GO:0016805	dipeptidase activity(GO:0016805)
1.1	11.6	GO:0005351	sugar:proton symporter activity(GO:0005351)
1.1	3.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.0	4.2	GO:0004370	glycerol kinase activity(GO:0004370)
1.0	1.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
1.0	18.8	GO:0005227	calcium activated cation channel activity(GO:0005227)
1.0	5.2	GO:0004994	somatostatin receptor activity(GO:0004994)
1.0	3.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.0	11.5	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.0	1.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
1.0	3.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.0	6.2	GO:0004383	guanylate cyclase activity(GO:0004383)
1.0	2.0	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
1.0	4.1	GO:0050786	RAGE receptor binding(GO:0050786)
1.0	25.5	GO:0005044	scavenger receptor activity(GO:0005044)
1.0	8.1	GO:0043422	protein kinase B binding(GO:0043422)
1.0	2.0	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.0	3.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
1.0	1.0	GO:0001962	alpha-1,3-galactosyltransferase activity(GO:0001962)
1.0	10.6	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.0	4.8	GO:0015922	aspartate oxidase activity(GO:0015922)
0.9	2.8	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.9	2.8	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.9	0.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.9	4.6	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.9	4.6	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.9	82.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.9	20.7	GO:0035591	signaling adaptor activity(GO:0035591)
0.9	2.7	GO:0045504	dynein heavy chain binding(GO:0045504)
0.9	3.5	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.9	2.6	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.9	2.6	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.9	16.7	GO:0070888	E-box binding(GO:0070888)
0.9	2.6	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.9	10.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.9	12.1	GO:0030552	cAMP binding(GO:0030552)
0.9	2.6	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.8	3.4	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.8	5.1	GO:0043495	protein anchor(GO:0043495)
0.8	9.2	GO:0051787	misfolded protein binding(GO:0051787)
0.8	0.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.8	5.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.8	0.8	GO:0031705	bombesin receptor binding(GO:0031705)
0.8	10.8	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.8	5.8	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.8	4.9	GO:0016421	CoA carboxylase activity(GO:0016421)
0.8	0.8	GO:0031402	sodium ion binding(GO:0031402)
0.8	1.6	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.8	29.0	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.8	23.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.8	48.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.8	3.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.8	3.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.8	86.3	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.8	196.9	GO:0003779	actin binding(GO:0003779)
0.8	24.1	GO:0019107	myristoyltransferase activity(GO:0019107)
0.8	5.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.7	5.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.7	252.8	GO:0005509	calcium ion binding(GO:0005509)
0.7	11.5	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.7	5.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.7	1.4	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.7	2.1	GO:0048030	disaccharide binding(GO:0048030)
0.7	2.7	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.7	10.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.7	1.3	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.7	7.3	GO:0051400	BH domain binding(GO:0051400)
0.7	10.6	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.7	2.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.7	2.0	GO:0002046	opsin binding(GO:0002046)
0.7	4.6	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.6	5.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.6	0.6	GO:0038100	nodal binding(GO:0038100)
0.6	1.9	GO:0050544	arachidonic acid binding(GO:0050544)
0.6	1.2	GO:0016415	octanoyltransferase activity(GO:0016415)
0.6	3.6	GO:0043236	laminin binding(GO:0043236)
0.6	1.8	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.6	1.8	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.6	1.8	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.6	5.3	GO:0015298	solute:cation antiporter activity(GO:0015298)
0.6	1.2	GO:0032190	acrosin binding(GO:0032190)
0.6	10.5	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.6	1.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.6	10.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6	2.3	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.6	2.3	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.6	1.7	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.5	0.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.5	15.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	0.5	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.5	1.6	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.5	2.6	GO:0033265	choline binding(GO:0033265)
0.5	1.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.5	23.9	GO:0003777	microtubule motor activity(GO:0003777)
0.5	1.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.5	14.8	GO:0017046	peptide hormone binding(GO:0017046)
0.5	0.5	GO:0016751	S-succinyltransferase activity(GO:0016751)
0.5	1.5	GO:0005217	intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.5	9.5	GO:0050699	WW domain binding(GO:0050699)
0.5	87.1	GO:0030695	GTPase regulator activity(GO:0030695)
0.5	9.8	GO:0004707	MAP kinase activity(GO:0004707)
0.5	2.0	GO:0034584	piRNA binding(GO:0034584)
0.5	1.9	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.5	1.4	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.5	9.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.5	2.7	GO:0019215	intermediate filament binding(GO:0019215)
0.5	3.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.4	1.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.4	0.8	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4	1.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4	23.3	GO:0008083	growth factor activity(GO:0008083)
0.4	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.4	4.0	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.4	1.6	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.4	2.0	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.4	2.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4	1.6	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4	3.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.4	1.1	GO:0004096	catalase activity(GO:0004096)
0.4	29.9	GO:0005179	hormone activity(GO:0005179)
0.4	1.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.4	4.1	GO:0070402	NADPH binding(GO:0070402)
0.4	0.4	GO:0051525	NFAT protein binding(GO:0051525)
0.4	1.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4	0.4	GO:0008410	CoA-transferase activity(GO:0008410)
0.4	1.5	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.4	1.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	1.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.4	1.8	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.3	1.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3	1.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.3	0.7	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.3	2.0	GO:0036310	annealing helicase activity(GO:0036310)
0.3	1.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3	0.9	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3	0.9	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.3	0.6	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.3	9.1	GO:0030674	protein binding, bridging(GO:0030674)
0.3	1.2	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
0.3	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.3	0.3	GO:0043199	sulfate binding(GO:0043199)
0.3	131.1	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.3	7.6	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.3	0.3	GO:0031013	troponin I binding(GO:0031013)
0.3	0.3	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.3	0.8	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.3	0.8	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3	0.8	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3	3.4	GO:0003774	motor activity(GO:0003774)
0.3	0.5	GO:0030519	snoRNP binding(GO:0030519)
0.3	3.8	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.2	1.7	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	0.2	GO:0045545	syndecan binding(GO:0045545)
0.2	0.2	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2	4.9	GO:0017091	AU-rich element binding(GO:0017091)
0.2	0.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.2	4.4	GO:0005518	collagen binding(GO:0005518)
0.2	2.5	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.2	0.4	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.2	0.4	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	4.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	0.5	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	0.9	GO:0001223	transcription coactivator binding(GO:0001223)
0.2	0.9	GO:0018856	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.2	0.5	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.2	1.5	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	12.2	GO:0004497	monooxygenase activity(GO:0004497)
0.2	0.8	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	2.3	GO:0005537	mannose binding(GO:0005537)
0.1	0.4	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.4	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.6	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	1.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	0.8	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	3.5	GO:0043826	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.1	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.4	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	1.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1	0.3	GO:0035514	DNA demethylase activity(GO:0035514)
0.1	1.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	13.1	GO:0005125	cytokine activity(GO:0005125)
0.1	0.9	GO:0004623	phospholipase A2 activity(GO:0004623)
0.1	0.2	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.5	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1	0.2	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.1	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.6	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	0.3	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	1.4	GO:0005267	potassium channel activity(GO:0005267)
0.1	0.7	GO:0052769	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1	0.7	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1	0.6	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	1.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.1	GO:0015927	trehalase activity(GO:0015927)
0.1	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	5.0	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	1.2	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.0	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.2	GO:0005550	pheromone binding(GO:0005550)
0.0	1.7	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	6.0	GO:0005549	odorant binding(GO:0005549)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.3	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.6	14.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
4.6	111.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
4.6	50.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
4.1	174.6	NABA COLLAGENS	Genes encoding collagen proteins
3.5	7.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
3.4	98.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
3.3	6.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
3.2	9.6	PID S1P S1P3 PATHWAY	S1P3 pathway
3.1	46.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
3.1	55.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
2.9	82.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
2.9	71.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.8	8.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
2.8	8.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
2.7	114.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
2.7	10.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
2.6	39.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
2.6	77.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
2.6	2.6	ST JAK STAT PATHWAY	Jak-STAT Pathway
2.6	5.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
2.4	59.2	PID EPHA FWDPATHWAY	EPHA forward signaling
2.4	16.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.3	25.6	PID ALK2 PATHWAY	ALK2 signaling events
2.3	27.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
2.2	53.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
2.1	25.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
2.1	14.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
2.1	4.1	PID S1P S1P2 PATHWAY	S1P2 pathway
2.0	16.1	PID ALK1 PATHWAY	ALK1 signaling events
2.0	316.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.9	26.7	PID REELIN PATHWAY	Reelin signaling pathway
1.9	1.9	PID S1P S1P1 PATHWAY	S1P1 pathway
1.8	30.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
1.7	13.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
1.7	51.8	PID BMP PATHWAY	BMP receptor signaling
1.6	26.7	PID FGF PATHWAY	FGF signaling pathway
1.6	404.0	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
1.5	1.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
1.5	26.5	PID RAS PATHWAY	Regulation of Ras family activation
1.4	188.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.3	16.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.3	9.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.3	43.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.3	19.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
1.3	13.0	ST G ALPHA S PATHWAY	G alpha s Pathway
1.3	25.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.3	17.9	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
1.2	33.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
1.2	9.3	PID S1P S1P4 PATHWAY	S1P4 pathway
1.1	21.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
1.1	11.9	PID EPHB FWD PATHWAY	EPHB forward signaling
1.0	27.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.0	7.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.9	7.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.9	18.7	PID AURORA A PATHWAY	Aurora A signaling
0.9	4.4	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.8	12.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.8	24.9	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.8	16.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.8	1.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.7	2.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	8.5	PID IL3 PATHWAY	IL3-mediated signaling events
0.7	9.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.7	133.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.6	4.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.6	1.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	0.6	PID SHP2 PATHWAY	SHP2 signaling
0.6	1.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	27.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.5	1.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.5	9.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	9.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.4	1.7	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	1.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.4	9.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	4.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	0.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.3	7.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.2	3.6	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.2	1.9	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	0.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	0.6	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.2	2.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	1.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	1.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.2	1.7	PID ENDOTHELIN PATHWAY	Endothelins
0.1	5.5	PID NOTCH PATHWAY	Notch signaling pathway
0.1	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	0.6	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	1.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	8.8	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
7.6	7.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
6.7	6.7	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
6.5	176.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
6.1	72.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
6.1	85.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
5.2	78.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
5.1	178.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
4.9	43.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
4.6	179.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
4.5	40.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
4.2	59.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
4.2	95.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
4.1	176.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
3.8	3.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
3.8	87.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
3.7	44.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
3.7	14.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
3.7	40.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
3.6	50.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
3.6	10.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
3.6	3.6	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
3.6	3.6	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
3.5	46.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
3.5	45.6	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
3.5	38.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
3.4	123.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
3.4	37.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
3.3	32.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
3.2	32.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
3.2	3.2	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
3.2	69.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
3.1	71.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
2.8	16.9	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
2.7	8.2	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
2.7	24.5	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
2.7	27.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.7	21.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
2.3	9.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
2.3	6.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
2.2	24.6	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
2.2	6.6	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
2.2	28.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
2.1	82.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
2.0	40.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
2.0	36.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
2.0	2.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
2.0	33.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.9	1.9	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
1.9	11.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
1.9	153.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
1.8	27.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.7	45.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
1.6	17.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
1.6	25.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
1.5	12.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
1.4	1.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
1.4	22.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
1.4	38.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
1.3	21.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
1.3	4.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.3	10.6	REACTOME OPSINS	Genes involved in Opsins
1.3	7.9	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
1.3	6.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
1.2	9.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
1.2	13.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.2	9.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
1.2	83.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
1.1	45.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
1.1	23.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.1	16.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
1.1	20.5	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.1	7.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.1	1.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.0	7.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
1.0	20.1	REACTOME KINESINS	Genes involved in Kinesins
0.9	12.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.9	10.9	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.9	8.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.9	0.9	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.9	9.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.9	13.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.9	6.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.9	2.6	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.8	10.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8	4.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.8	1.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.8	14.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.8	18.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.8	5.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.8	9.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7	3.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.7	31.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.7	10.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.6	2.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.6	3.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.6	0.6	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.6	13.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6	6.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6	4.0	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.6	1.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.5	4.9	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.5	56.5	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.5	0.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5	12.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.5	4.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.5	9.8	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.4	1.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4	40.8	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.4	1.8	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.4	1.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4	4.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	4.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.3	0.3	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.3	2.6	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.3	4.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	15.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	0.7	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	5.5	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.2	1.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	4.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	15.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	1.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	0.7	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	2.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.0	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling

Results for Klf16_Sp8

Z-value: 4.51

Motif logo

Transcription factors associated with Klf16_Sp8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Klf16_Sp8 motif across conditions

Conditions sorted by the z-value of the Klf16_Sp8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf16_Sp8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: