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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Klf4_Sp3

Z-value: 13.37

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Transcription factors associated with Klf4_Sp3

Gene Symbol	Gene ID	Gene Info
Klf4 Ensembl NCBI MGI UniProt	ENSMUSG00000003032.8	Kruppel-like factor 4 (gut)
Sp3 Ensembl NCBI MGI UniProt	ENSMUSG00000027109.10	trans-acting transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_55532892_55533335	Klf4	647	0.676390	-0.55	1.3e-05	Click!
chr4_55526526_55526677	Klf4	5169	0.175033	-0.48	2.5e-04	Click!
chr4_55531336_55531735	Klf4	235	0.916196	-0.45	5.7e-04	Click!
chr4_55532729_55532885	Klf4	341	0.861676	-0.44	7.0e-04	Click!
chr4_55530574_55530971	Klf4	998	0.501016	-0.44	8.2e-04	Click!
chr2_72975841_72976127	Sp3	3302	0.171313	0.67	2.7e-08	Click!
chr2_72978962_72979321	Sp3	145	0.674806	0.66	3.4e-08	Click!
chr2_72913506_72913657	Sp3	27503	0.142546	-0.65	5.8e-08	Click!
chr2_72908187_72908356	Sp3	32813	0.135708	0.62	3.9e-07	Click!
chr2_72889510_72889661	Sp3	51499	0.107544	0.56	7.3e-06	Click!

Activity of the Klf4_Sp3 motif across conditions

Conditions sorted by the z-value of the Klf4_Sp3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_125095392_125097556	223.92	Chd4	chromodomain helicase DNA binding protein 4	95	0.84
chr2_170130477_170131578	216.97	Zfp217	zinc finger protein 217	193	0.97
chr10_80576603_80578409	209.76	Klf16	Kruppel-like factor 16	185	0.86
chr2_153492229_153493481	208.27	4930404H24Rik	RIKEN cDNA 4930404H24 gene	65	0.82
chr5_109557850_109558797	196.90	Crlf2	cytokine receptor-like factor 2	613	0.67
chr4_140701770_140702866	174.10	Rcc2	regulator of chromosome condensation 2	845	0.47
chr10_120216764_120217346	169.65	Tmbim4	transmembrane BAX inhibitor motif containing 4	3633	0.18
chr17_34898151_34899707	161.43	Ehmt2	euchromatic histone lysine N-methyltransferase 2	25	0.87
chr14_20793233_20794132	159.91	Camk2g	calcium/calmodulin-dependent protein kinase II gamma	284	0.68
chr8_70698268_70700333	157.48	Jund	jun D proto-oncogene	351	0.45
chr2_174329445_174331091	156.55	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	19	0.97
chrY_90771840_90772811	153.27	Gm47283	predicted gene, 47283	12413	0.17
chr3_51340298_51341882	152.65	Elf2	E74-like factor 2	427	0.74
chr11_74837693_74838808	148.91	Mnt	max binding protein	782	0.52
chr7_127768560_127769629	143.00	Orai3	ORAI calcium release-activated calcium modulator 3	721	0.4
chr5_137530580_137532081	140.34	Gnb2	guanine nucleotide binding protein (G protein), beta 2	33	0.9
chrX_142680720_142682167	139.30	Tmem164	transmembrane protein 164	25	0.98
chr10_69910043_69910940	138.97	Ank3	ankyrin 3, epithelial	4374	0.35
chrX_169997850_169998483	137.45	Gm15247	predicted gene 15247	11227	0.14
chr11_70021148_70021981	135.20	Dlg4	discs large MAGUK scaffold protein 4	2356	0.11
chr11_98741567_98742727	132.10	Thra	thyroid hormone receptor alpha	11	0.95
chr14_115040506_115042372	131.09	Mir17hg	Mir17 host gene (non-protein coding)	1440	0.19
chr8_70538591_70539987	128.10	Ell	elongation factor RNA polymerase II	168	0.88
chr10_127508848_127510720	127.77	Stac3	SH3 and cysteine rich domain 3	2559	0.15
chr15_58140746_58142050	127.33	Wdyhv1	WDYHV motif containing 1	6	0.96
chr15_98608664_98610204	123.14	Adcy6	adenylate cyclase 6	598	0.55
chr11_69996486_69997590	122.95	Phf23	PHD finger protein 23	47	0.91
chr14_14347096_14348750	121.16	Gm48860	predicted gene, 48860	659	0.44
chr14_25606696_25608421	121.07	Zmiz1	zinc finger, MIZ-type containing 1	201	0.95
chr8_120486990_120488549	120.74	Gse1	genetic suppressor element 1, coiled-coil protein	678	0.64
chr9_109094576_109096217	119.42	Plxnb1	plexin B1	7	0.95
chr7_127026546_127028177	117.92	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	324	0.58
chr2_75703696_75705127	117.79	Nfe2l2	nuclear factor, erythroid derived 2, like 2	78	0.81
chr5_140439026_140439687	115.39	Eif3b	eukaryotic translation initiation factor 3, subunit B	586	0.63
chr5_144357735_144358915	112.44	Dmrt1i	Dmrt1 interacting ncRNA	200	0.51
chr10_79779826_79781202	112.39	Fstl3	follistatin-like 3	67	0.92
chr11_100938783_100940230	112.16	Stat3	signal transducer and activator of transcription 3	27	0.97
chr9_65826224_65827697	112.01	Zfp609	zinc finger protein 609	604	0.65
chr5_137786077_137787112	110.97	Mepce	methylphosphate capping enzyme	69	0.92
chr10_121475538_121476618	109.83	Rassf3	Ras association (RalGDS/AF-6) domain family member 3	269	0.86
chr14_55824498_55825973	109.56	Nfatc4	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4	198	0.87
chr15_100747217_100747460	109.34	Slc4a8	solute carrier family 4 (anion exchanger), member 8	14409	0.11
chr11_117838543_117838973	108.12	Afmid	arylformamidase	6485	0.09
chr11_74896307_74898160	107.61	Sgsm2	small G protein signaling modulator 2	173	0.84
chr4_107253005_107253839	107.25	Lrrc42	leucine rich repeat containing 42	110	0.58
chr2_25982690_25983958	105.97	Camsap1	calmodulin regulated spectrin-associated protein 1	42	0.97
chr9_59577641_59578825	105.50	Celf6	CUGBP, Elav-like family member 6	41	0.97
chr7_28179836_28180482	103.94	Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	107	0.93
chr10_128525093_128526268	103.47	Esyt1	extended synaptotagmin-like protein 1	188	0.63
chr14_14354416_14355184	103.01	Il3ra	interleukin 3 receptor, alpha chain	5179	0.12
chr6_49367200_49368123	102.70	Fam221a	family with sequence similarity 221, member A	78	0.97
chr11_117968531_117970182	102.07	Socs3	suppressor of cytokine signaling 3	95	0.96
chr17_47923769_47925323	101.48	Foxp4	forkhead box P4	70	0.96
chr6_83456116_83457458	101.35	Tet3	tet methylcytosine dioxygenase 3	395	0.77
chr5_134688076_134689277	100.64	Limk1	LIM-domain containing, protein kinase	78	0.96
chr10_80538778_80539361	99.09	Atp8b3	ATPase, class I, type 8B, member 3	21	0.95
chr14_40966316_40967615	99.07	Tspan14	tetraspanin 14	158	0.96
chr10_69908447_69908713	97.92	Ank3	ankyrin 3, epithelial	6285	0.32
chr13_58006958_58007325	97.43	Mir874	microRNA 874	16059	0.21
chr4_156197393_156197799	97.05	Agrn	agrin	108	0.92
chr9_61370339_61371660	95.45	Gm10655	predicted gene 10655	628	0.63
chr8_107030704_107031406	94.75	Gm16208	predicted gene 16208	133	0.53
chrX_51204673_51205680	93.28	Mbnl3	muscleblind like splicing factor 3	656	0.65
chr11_69837611_69838644	93.26	Nlgn2	neuroligin 2	343	0.43
chr2_153528510_153529333	92.61	Nol4l	nucleolar protein 4-like	1050	0.54
chr19_4282702_4283651	92.44	Ankrd13d	ankyrin repeat domain 13 family, member D	39	0.93
chr18_24259035_24259422	91.99	Gm7701	predicted gene 7701	1850	0.37
chr5_111239248_111239612	91.95	Ttc28	tetratricopeptide repeat domain 28	4115	0.24
chr9_21917486_21918482	91.86	Rab3d	RAB3D, member RAS oncogene family	105	0.93
chr4_45530265_45531442	91.77	Shb	src homology 2 domain-containing transforming protein B	523	0.73
chr11_74831594_74833056	91.58	Mnt	max binding protein	1405	0.31
chr10_127667525_127668413	90.04	Nab2	Ngfi-A binding protein 2	599	0.4
chr4_134081752_134082448	89.81	Crybg2	crystallin beta-gamma domain containing 2	212	0.88
chr3_100488535_100489982	89.75	Tent5c	terminal nucleotidyltransferase 5C	60	0.85
chr16_93711386_93712056	89.50	Dop1b	DOP1 leucine zipper like protein B	183	0.93
chr3_85887352_85888077	89.20	4933425M03Rik	RIKEN cDNA 4933425M03 gene	23	0.56
chr15_79690079_79691459	89.20	Gtpbp1	GTP binding protein 1	76	0.92
chr14_69321815_69322332	89.10	Gm16677	predicted gene, 16677	15009	0.09
chr6_124919273_124920636	89.09	Ptms	parathymosin	149	0.88
chr14_69540059_69540582	89.07	Gm27174	predicted gene 27174	15012	0.09
chr2_154569188_154570416	88.41	E2f1	E2F transcription factor 1	82	0.95
chr14_70074487_70075571	87.42	Egr3	early growth response 3	2174	0.25
chr5_124862398_124863348	87.23	Zfp664	zinc finger protein 664	109	0.84
chr9_59750348_59751247	86.79	Senp8	SUMO/sentrin specific peptidase 8	87	0.51
chr7_45784749_45786509	86.77	Lmtk3	lemur tyrosine kinase 3	119	0.87
chr7_16781038_16782438	85.52	Slc1a5	solute carrier family 1 (neutral amino acid transporter), member 5	370	0.78
chr7_36697059_36698174	85.34	Tshz3	teashirt zinc finger family member 3	502	0.7
chr11_105589210_105590456	85.15	Tanc2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	153	0.96
chr5_137349031_137350198	84.99	Ephb4	Eph receptor B4	495	0.62
chr4_149425818_149427108	84.98	Ube4b	ubiquitination factor E4B	137	0.94
chr7_30534433_30535339	84.72	Arhgap33	Rho GTPase activating protein 33	111	0.87
chr7_25249061_25250506	84.69	Erf	Ets2 repressor factor	947	0.33
chr11_80779330_80780330	84.51	Myo1d	myosin ID	173	0.95
chr5_36581343_36582156	84.49	Tbc1d14	TBC1 domain family, member 14	43	0.97
chr8_90907824_90909226	84.35	Chd9	chromodomain helicase DNA binding protein 9	89	0.52
chr17_47909349_47909983	84.12	Gm15556	predicted gene 15556	12712	0.13
chr5_134551282_134552920	83.86	Gm42884	predicted gene 42884	44	0.81
chr5_144255011_144256245	83.79	Bri3	brain protein I3	394	0.56
chr7_25689001_25689947	83.40	Tgfb1	transforming growth factor, beta 1	547	0.58
chr17_30004516_30005139	83.39	Zfand3	zinc finger, AN1-type domain 3	94	0.55
chr6_90988622_90989360	83.29	Iqsec1	IQ motif and Sec7 domain 1	306	0.9
chr1_166002288_166003185	83.25	Pou2f1	POU domain, class 2, transcription factor 1	58	0.72
chr7_100492773_100493523	83.24	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	189	0.88
chr5_140829777_140830873	83.16	Gna12	guanine nucleotide binding protein, alpha 12	106	0.97
chr8_70791948_70793334	82.99	Mast3	microtubule associated serine/threonine kinase 3	204	0.83
chr2_106692893_106694599	82.63	Mpped2	metallophosphoesterase domain containing 2	477	0.85
chr19_41482494_41483686	82.62	Lcor	ligand dependent nuclear receptor corepressor	61	0.98
chr5_22344110_22345571	81.83	Reln	reelin	138	0.95
chr17_47694297_47695658	81.81	Frs3	fibroblast growth factor receptor substrate 3	221	0.44
chr4_152086414_152087408	81.79	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	53	0.96
chr11_105125823_105126961	81.60	Mettl2	methyltransferase like 2	33	0.97
chr8_120276000_120276974	81.59	Gse1	genetic suppressor element 1, coiled-coil protein	48031	0.12
chr12_24651648_24652438	81.29	Klf11	Kruppel-like factor 11	111	0.96
chr11_116624141_116624473	81.06	Rhbdf2	rhomboid 5 homolog 2	60	0.95
chr10_61534398_61535221	80.92	Gm17829	predicted gene, 17829	24224	0.1
chr17_27826103_27826412	80.68	Ilrun	inflammation and lipid regulator with UBA-like and NBR1-like domains	5609	0.13
chrX_48284788_48285532	80.65	Gm22528	predicted gene, 22528	14419	0.13
chr2_156720289_156721547	80.47	4930405A21Rik	RIKEN cDNA 4930405A21 gene	9	0.6
chr12_8770800_8772245	80.22	Sdc1	syndecan 1	109	0.78
chr9_50856310_50857724	80.14	Ppp2r1b	protein phosphatase 2, regulatory subunit A, beta	38	0.97
chr6_72097140_72098281	79.56	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	47	0.96
chr2_48949106_48950119	79.39	Mbd5	methyl-CpG binding domain protein 5	89	0.8
chr10_93666253_93666601	79.24	Gm8580	predicted gene 8580	581	0.67
chr19_6969291_6970359	79.23	Plcb3	phospholipase C, beta 3	11	0.93
chr16_44357986_44358161	79.01	Spice1	spindle and centriole associated protein 1	9578	0.2
chr2_143915149_143916129	78.79	Dstn	destrin	319	0.87
chr19_43493324_43493679	78.01	Cnnm1	cyclin M1	15	0.97
chr11_77607040_77608322	77.72	Taok1	TAO kinase 1	134	0.94
chr11_117114876_117115708	77.15	Sec14l1	SEC14-like lipid binding 1	40	0.96
chr5_129941152_129942065	76.89	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1	362	0.76
chr11_98766610_98767640	76.70	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3301	0.13
chr11_98941353_98942362	76.46	Rara	retinoic acid receptor, alpha	2145	0.18
chr4_83623239_83623556	75.92	Gm27046	predicted gene, 27046	26094	0.17
chr15_36792317_36793249	75.80	Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	369	0.84
chr13_37825583_37827437	75.50	Rreb1	ras responsive element binding protein 1	195	0.94
chr11_117792296_117792500	75.27	Gm11724	predicted gene 11724	1085	0.24
chr4_149954471_149955779	75.26	Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	82	0.97
chr3_88532663_88533971	74.56	Mex3a	mex3 RNA binding family member A	922	0.31
chr11_11684707_11686418	74.52	Gm11999	predicted gene 11999	162	0.73
chr1_86525613_86527056	74.44	Ptma	prothymosin alpha	392	0.81
chr8_84979246_84980613	74.42	Junb	jun B proto-oncogene	1211	0.19
chr4_88032518_88033581	74.33	Mllt3	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3	232	0.71
chr7_141215165_141215936	74.28	Rassf7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	310	0.71
chr6_120665862_120666733	74.23	Cecr2	CECR2, histone acetyl-lysine reader	72	0.98
chr11_116077910_116078580	74.01	Unc13d	unc-13 homolog D	284	0.82
chr7_48880950_48881793	73.98	Gm2788	predicted gene 2788	71	0.71
chr5_113164821_113165497	73.69	Gm43094	predicted gene 43094	1075	0.34
chr12_12941527_12942979	73.67	Mycn	v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived	339	0.83
chr3_65658208_65659857	73.49	Mir8120	microRNA 8120	256	0.89
chr7_16874715_16875380	73.27	9330104G04Rik	RIKEN cDNA 9330104G04 gene	161	0.62
chr8_104395019_104396337	72.89	Cmtm4	CKLF-like MARVEL transmembrane domain containing 4	129	0.93
chr17_70850487_70852089	72.89	Tgif1	TGFB-induced factor homeobox 1	81	0.94
chr9_106821518_106822739	72.72	Dcaf1	DDB1 and CUL4 associated factor 1	254	0.89
chr15_98933816_98934775	72.67	Gm41396	predicted gene, 41396	30	0.62
chr3_144720129_144720738	72.00	Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	98	0.95
chr5_140034121_140034770	71.99	Gm43702	predicted gene 43702	2269	0.28
chr12_101028530_101029714	71.96	Ccdc88c	coiled-coil domain containing 88C	66	0.95
chr5_139736302_139736636	71.88	Micall2	MICAL-like 2	133	0.95
chr4_154025644_154026533	71.79	Smim1	small integral membrane protein 1	51	0.95
chr4_129188973_129189769	71.70	S100pbp	S100P binding protein	127	0.78
chr4_129513695_129514851	71.67	Marcksl1	MARCKS-like 1	692	0.46
chr4_154882060_154882342	71.65	Mmel1	membrane metallo-endopeptidase-like 1	8	0.97
chr7_45017042_45018019	71.47	Rras	related RAS viral (r-ras) oncogene	431	0.52
chr7_16285532_16286609	71.45	Ccdc9	coiled-coil domain containing 9	45	0.95
chr9_57644752_57646108	71.25	Csk	c-src tyrosine kinase	187	0.91
chr8_70819994_70820875	71.12	Il12rb1	interleukin 12 receptor, beta 1	7218	0.07
chr17_28809053_28809624	70.88	Brpf3	bromodomain and PHD finger containing, 3	321	0.81
chr9_44498071_44499796	70.87	Bcl9l	B cell CLL/lymphoma 9-like	203	0.84
chr17_88065293_88066116	70.86	Fbxo11	F-box protein 11	413	0.86
chr6_97204968_97206158	70.85	Uba3	ubiquitin-like modifier activating enzyme 3	2	0.97
chr11_113651275_113651628	70.85	Slc39a11	solute carrier family 39 (metal ion transporter), member 11	1372	0.29
chr10_127062800_127064205	70.76	Cdk4	cyclin-dependent kinase 4	32	0.93
chr5_115506441_115507217	70.51	Pxn	paxillin	21	0.94
chr14_62760761_62761843	70.40	Ints6	integrator complex subunit 6	133	0.95
chr9_106367425_106368835	70.40	Dusp7	dual specificity phosphatase 7	502	0.7
chr11_75651168_75652336	70.10	Myo1c	myosin IC	242	0.88
chr3_144198270_144199266	70.08	Gm43445	predicted gene 43445	494	0.79
chr7_27258127_27259252	69.94	Numbl	numb-like	36	0.91
chr18_67288589_67289806	69.85	Impa2	inositol (myo)-1(or 4)-monophosphatase 2	11	0.97
chr11_12036502_12038049	69.62	Grb10	growth factor receptor bound protein 10	126	0.97
chr16_30063252_30064537	69.54	Hes1	hes family bHLH transcription factor 1	490	0.76
chr5_96162084_96163134	69.19	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	619	0.75
chr17_47535748_47536285	69.02	Ccnd3	cyclin D3	30775	0.1
chr7_83891433_83892352	69.02	Mesd	mesoderm development LRP chaperone	108	0.78
chr11_85139345_85140659	68.94	Usp32	ubiquitin specific peptidase 32	34	0.97
chr4_32982786_32983988	68.78	Rragd	Ras-related GTP binding D	67	0.96
chr15_38078009_38079076	68.45	Ubr5	ubiquitin protein ligase E3 component n-recognin 5	117	0.87
chr3_88492417_88493241	68.42	Lmna	lamin A	483	0.61
chr11_69366461_69367262	68.11	Chd3	chromodomain helicase DNA binding protein 3	2082	0.14
chrX_36988645_36990253	67.71	Septin6	septin 6	42	0.97
chr17_32389112_32389653	67.38	Wiz	widely-interspaced zinc finger motifs	6	0.84
chr5_140647773_140649317	67.23	Ttyh3	tweety family member 3	452	0.77
chr2_121289033_121290183	66.40	Map1a	microtubule-associated protein 1 A	8	0.96
chr2_93461958_93462733	65.94	Cd82	CD82 antigen	41	0.97
chr2_165326390_165327162	65.82	Elmo2	engulfment and cell motility 2	297	0.87
chr7_28597227_28598470	65.77	Pak4	p21 (RAC1) activated kinase 4	238	0.53
chr8_11008854_11009914	65.72	Irs2	insulin receptor substrate 2	926	0.42
chr14_75130478_75131409	65.69	Lrrc63	leucine rich repeat containing 63	62	0.63
chr2_118662761_118664171	65.25	Pak6	p21 (RAC1) activated kinase 6	163	0.94
chr7_29210966_29212124	65.22	Catsperg1	cation channel sperm associated auxiliary subunit gamma 1	50	0.94

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf4_Sp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
69.9	209.7	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
67.9	203.6	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
67.3	134.6	GO:0060375	regulation of mast cell differentiation(GO:0060375)
64.5	257.8	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
59.8	179.5	GO:0008050	female courtship behavior(GO:0008050)
59.5	238.2	GO:0031581	hemidesmosome assembly(GO:0031581)
58.3	58.3	GO:0090239	regulation of histone H4 acetylation(GO:0090239) positive regulation of histone H4 acetylation(GO:0090240)
56.0	168.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
55.1	165.4	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
54.8	164.3	GO:0036166	phenotypic switching(GO:0036166)
53.0	159.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
49.5	148.5	GO:0002432	granuloma formation(GO:0002432)
48.9	244.3	GO:0072553	terminal button organization(GO:0072553)
47.7	143.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
46.6	139.7	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
46.4	92.8	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
46.2	277.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
45.5	91.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
44.2	132.7	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
44.2	132.7	GO:0040031	snRNA modification(GO:0040031)
43.6	87.3	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
43.2	129.5	GO:0051599	response to hydrostatic pressure(GO:0051599)
42.8	171.4	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
41.1	123.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
40.8	163.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
40.5	121.5	GO:0034499	late endosome to Golgi transport(GO:0034499)
40.4	40.4	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
40.4	201.8	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
40.1	80.3	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
39.7	119.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
39.4	118.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
39.1	117.3	GO:0007525	somatic muscle development(GO:0007525)
39.0	39.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
39.0	39.0	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
38.7	77.4	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
38.4	153.6	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
38.1	152.5	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
38.0	190.0	GO:0060480	lung goblet cell differentiation(GO:0060480)
37.9	189.3	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
37.0	74.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
36.4	72.8	GO:0050904	diapedesis(GO:0050904)
36.3	217.7	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
35.8	179.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
35.4	141.7	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
35.0	140.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
34.6	138.6	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
34.4	68.9	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
33.9	33.9	GO:0048769	sarcomerogenesis(GO:0048769)
33.9	33.9	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
33.8	135.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
33.5	100.6	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
33.5	134.1	GO:0023021	termination of signal transduction(GO:0023021)
33.5	67.0	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
33.3	100.0	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
32.9	65.9	GO:0071462	cellular response to water stimulus(GO:0071462)
32.9	32.9	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
32.3	129.0	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
32.2	96.6	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
32.0	128.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
31.7	95.2	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
31.6	126.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
31.5	125.9	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
31.4	125.6	GO:0006499	N-terminal protein myristoylation(GO:0006499)
31.4	125.4	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
31.1	155.3	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
31.1	93.2	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
31.0	93.1	GO:1990705	cholangiocyte proliferation(GO:1990705)
31.0	92.9	GO:1903061	positive regulation of protein lipidation(GO:1903061)
31.0	31.0	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
30.9	154.4	GO:0070627	ferrous iron import(GO:0070627)
30.8	123.3	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
30.8	184.7	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
30.7	30.7	GO:0046822	regulation of nucleocytoplasmic transport(GO:0046822)
30.5	91.5	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
30.5	121.9	GO:0007296	vitellogenesis(GO:0007296)
30.0	60.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
29.7	89.1	GO:1902075	cellular response to salt(GO:1902075)
29.6	88.9	GO:0015793	glycerol transport(GO:0015793)
29.6	118.4	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
29.6	88.7	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
29.5	117.8	GO:0090168	Golgi reassembly(GO:0090168)
29.4	117.8	GO:0043622	cortical microtubule organization(GO:0043622)
29.4	88.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
29.3	88.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
29.0	406.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
29.0	115.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
28.7	86.1	GO:0006543	glutamine catabolic process(GO:0006543)
28.6	57.2	GO:0035928	rRNA import into mitochondrion(GO:0035928)
28.2	56.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
28.2	56.3	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
28.1	196.5	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
28.0	139.9	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
27.8	167.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
27.8	55.6	GO:0070889	platelet alpha granule organization(GO:0070889)
27.8	83.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
27.7	27.7	GO:0006680	glucosylceramide catabolic process(GO:0006680)
27.7	138.4	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
27.6	55.2	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
27.3	136.7	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
27.3	136.7	GO:0050812	regulation of acyl-CoA biosynthetic process(GO:0050812)
27.1	27.1	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
27.0	81.1	GO:0006741	NADP biosynthetic process(GO:0006741)
27.0	215.8	GO:0043983	histone H4-K12 acetylation(GO:0043983)
26.9	134.7	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
26.9	80.8	GO:0000087	mitotic M phase(GO:0000087)
26.9	80.6	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
26.8	134.1	GO:1903276	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
26.8	26.8	GO:1901420	negative regulation of response to alcohol(GO:1901420)
26.7	106.7	GO:0009757	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
26.6	239.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
26.4	105.7	GO:0070836	caveola assembly(GO:0070836)
26.4	131.9	GO:0075525	viral translational termination-reinitiation(GO:0075525)
26.3	52.7	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
26.2	78.5	GO:0061113	pancreas morphogenesis(GO:0061113)
26.0	130.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
26.0	26.0	GO:0002159	desmosome assembly(GO:0002159)
26.0	26.0	GO:0032808	lacrimal gland development(GO:0032808)
25.9	51.8	GO:1903334	positive regulation of protein folding(GO:1903334)
25.8	77.3	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
25.8	77.3	GO:0097167	circadian regulation of translation(GO:0097167)
25.6	51.2	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
25.5	76.6	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
25.5	76.5	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
25.5	50.9	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
25.4	127.0	GO:0061687	detoxification of inorganic compound(GO:0061687)
25.3	25.3	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
25.2	126.0	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
25.2	50.3	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
25.1	50.2	GO:0018992	germ-line sex determination(GO:0018992)
25.1	301.3	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
25.1	100.3	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
25.0	75.0	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
24.9	99.6	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
24.9	99.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
24.9	24.9	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
24.8	74.4	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
24.8	99.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
24.8	49.5	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
24.7	148.3	GO:0046060	dATP metabolic process(GO:0046060)
24.6	172.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
24.6	123.1	GO:0061635	regulation of protein complex stability(GO:0061635)
24.6	24.6	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
24.6	73.7	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
24.5	24.5	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
24.5	73.5	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
24.5	73.4	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
24.4	97.6	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
24.3	219.0	GO:0034063	stress granule assembly(GO:0034063)
24.2	96.9	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
24.1	72.4	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
24.0	24.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
24.0	72.0	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
23.8	71.3	GO:0048388	endosomal lumen acidification(GO:0048388)
23.8	95.1	GO:0003091	renal water homeostasis(GO:0003091)
23.8	118.9	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
23.7	71.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
23.7	23.7	GO:0043096	purine nucleobase salvage(GO:0043096)
23.7	71.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
23.6	94.4	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
23.6	47.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
23.5	70.6	GO:0046208	spermine catabolic process(GO:0046208)
23.5	47.0	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
23.5	211.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
23.4	23.4	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
23.3	23.3	GO:0010324	membrane invagination(GO:0010324)
23.3	162.9	GO:0001842	neural fold formation(GO:0001842)
23.3	93.0	GO:0003096	renal sodium ion transport(GO:0003096)
23.2	69.7	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
23.2	116.0	GO:0070544	histone H3-K36 demethylation(GO:0070544)
23.2	46.4	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
23.2	69.5	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
23.2	69.5	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
23.1	69.4	GO:0080009	mRNA methylation(GO:0080009)
23.1	69.3	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
23.1	115.4	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
23.0	23.0	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
22.9	91.5	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
22.9	137.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
22.8	228.1	GO:0035518	histone H2A monoubiquitination(GO:0035518)
22.7	272.2	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
22.7	136.0	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
22.6	271.7	GO:0070828	heterochromatin organization(GO:0070828)
22.6	90.5	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
22.6	203.6	GO:0006337	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
22.6	22.6	GO:0071594	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
22.5	45.0	GO:0021924	cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
22.3	22.3	GO:0006678	glucosylceramide metabolic process(GO:0006678)
22.3	66.9	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
22.3	66.9	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
22.3	133.6	GO:0016266	O-glycan processing(GO:0016266)
22.2	66.7	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
22.2	44.5	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
22.2	66.6	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
22.2	88.7	GO:0097039	protein linear polyubiquitination(GO:0097039)
22.0	22.0	GO:0061184	positive regulation of dermatome development(GO:0061184)
22.0	43.9	GO:0006344	maintenance of chromatin silencing(GO:0006344)
21.9	65.8	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
21.9	263.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
21.9	21.9	GO:0052041	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
21.9	21.9	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
21.9	43.8	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
21.9	109.3	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
21.8	21.8	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
21.8	21.8	GO:1902307	positive regulation of sodium ion transmembrane transport(GO:1902307) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
21.8	152.3	GO:0015838	amino-acid betaine transport(GO:0015838)
21.7	21.7	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
21.7	108.7	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
21.7	21.7	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
21.7	21.7	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
21.6	64.9	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
21.6	86.4	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
21.6	64.7	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
21.6	237.2	GO:0007035	vacuolar acidification(GO:0007035)
21.5	64.6	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
21.4	150.1	GO:0048680	positive regulation of axon regeneration(GO:0048680)
21.4	85.6	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
21.4	85.5	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
21.3	42.6	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
21.3	21.3	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
21.2	106.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
21.2	105.8	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
21.1	21.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
21.0	63.0	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
21.0	21.0	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
21.0	125.8	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
21.0	251.4	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
20.9	146.5	GO:0097062	dendritic spine maintenance(GO:0097062)
20.9	167.5	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
20.9	41.9	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
20.9	208.9	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
20.9	20.9	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
20.8	291.6	GO:0043984	histone H4-K16 acetylation(GO:0043984)
20.8	124.7	GO:0006526	arginine biosynthetic process(GO:0006526)
20.8	62.3	GO:0006982	response to lipid hydroperoxide(GO:0006982)
20.7	124.3	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
20.7	124.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
20.7	124.0	GO:0090043	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
20.6	20.6	GO:0042117	monocyte activation(GO:0042117)
20.5	61.5	GO:0070293	renal absorption(GO:0070293)
20.5	20.5	GO:0010985	negative regulation of lipoprotein particle clearance(GO:0010985)
20.4	81.7	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
20.4	40.9	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
20.4	61.3	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
20.4	40.8	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
20.4	40.8	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
20.4	81.5	GO:0048102	autophagic cell death(GO:0048102)
20.4	61.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
20.3	101.7	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
20.3	61.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
20.3	40.6	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
20.2	20.2	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
20.2	121.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
20.2	40.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
20.2	201.6	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
20.0	80.2	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
20.0	60.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
20.0	60.0	GO:0003032	detection of oxygen(GO:0003032)
20.0	79.9	GO:1904752	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
20.0	439.2	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
20.0	20.0	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
20.0	39.9	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
19.9	59.8	GO:0018199	peptidyl-glutamine modification(GO:0018199)
19.9	119.1	GO:0007097	nuclear migration(GO:0007097)
19.8	19.8	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
19.8	39.6	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
19.8	19.8	GO:0003415	chondrocyte hypertrophy(GO:0003415)
19.8	59.3	GO:0046340	diacylglycerol catabolic process(GO:0046340)
19.8	39.5	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
19.7	39.4	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
19.7	39.4	GO:1900221	regulation of beta-amyloid clearance(GO:1900221)
19.6	19.6	GO:0090205	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
19.6	215.7	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
19.6	58.7	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
19.5	58.6	GO:0032439	endosome localization(GO:0032439)
19.5	116.9	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
19.4	213.9	GO:0032801	receptor catabolic process(GO:0032801)
19.4	19.4	GO:0006573	valine metabolic process(GO:0006573)
19.4	155.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
19.4	96.9	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
19.3	96.7	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
19.3	19.3	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
19.3	96.4	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
19.3	192.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
19.1	95.5	GO:0044351	macropinocytosis(GO:0044351)
19.1	76.4	GO:0001969	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
19.1	19.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
19.1	76.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
19.1	57.2	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
19.0	57.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
19.0	57.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
19.0	76.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
19.0	57.0	GO:0042938	dipeptide transport(GO:0042938)
18.9	94.7	GO:0048194	Golgi vesicle budding(GO:0048194)
18.8	18.8	GO:0034729	histone H3-K79 methylation(GO:0034729)
18.8	37.7	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
18.7	56.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
18.7	112.4	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
18.7	56.1	GO:0008228	opsonization(GO:0008228)
18.7	37.4	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
18.7	167.9	GO:0050872	white fat cell differentiation(GO:0050872)
18.6	130.5	GO:0015825	L-serine transport(GO:0015825)
18.6	74.5	GO:1903715	regulation of aerobic respiration(GO:1903715)
18.6	409.5	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
18.6	55.8	GO:1904354	negative regulation of telomere capping(GO:1904354)
18.5	18.5	GO:0003166	bundle of His development(GO:0003166)
18.5	129.7	GO:0060352	cell adhesion molecule production(GO:0060352)
18.5	110.9	GO:0050917	sensory perception of umami taste(GO:0050917)
18.5	92.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
18.4	110.6	GO:0010668	ectodermal cell differentiation(GO:0010668)
18.4	36.8	GO:1900238	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
18.4	18.4	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
18.3	18.3	GO:1903012	positive regulation of bone development(GO:1903012)
18.3	55.0	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
18.3	55.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
18.3	18.3	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
18.3	54.9	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
18.3	54.8	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
18.3	36.5	GO:0061010	gall bladder development(GO:0061010)
18.2	72.7	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
18.2	54.5	GO:1903960	negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
18.2	36.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
18.2	54.5	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
18.1	18.1	GO:0031639	plasminogen activation(GO:0031639)
18.1	72.5	GO:0071139	resolution of recombination intermediates(GO:0071139)
18.1	72.5	GO:1902969	mitotic DNA replication(GO:1902969)
18.1	36.2	GO:0060023	soft palate development(GO:0060023)
18.1	126.6	GO:0000059	protein import into nucleus, docking(GO:0000059)
18.1	54.3	GO:0034421	post-translational protein acetylation(GO:0034421)
18.1	36.2	GO:1902896	terminal web assembly(GO:1902896)
18.1	54.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
18.0	18.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
18.0	36.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
18.0	53.9	GO:0045900	negative regulation of translational elongation(GO:0045900)
17.9	53.8	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
17.9	35.9	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
17.9	35.9	GO:0001922	B-1 B cell homeostasis(GO:0001922)
17.9	17.9	GO:0006833	water transport(GO:0006833)
17.9	71.6	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
17.9	53.7	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
17.9	143.1	GO:0048541	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
17.8	124.9	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
17.8	53.5	GO:0002337	B-1a B cell differentiation(GO:0002337)
17.8	89.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
17.8	17.8	GO:0036480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
17.7	35.5	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
17.7	124.0	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
17.7	35.4	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
17.6	17.6	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
17.6	123.0	GO:0035372	protein localization to microtubule(GO:0035372)
17.5	52.6	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
17.5	17.5	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
17.5	209.9	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
17.5	52.5	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
17.5	69.8	GO:0019081	viral translation(GO:0019081) IRES-dependent viral translational initiation(GO:0075522)
17.4	34.9	GO:0018343	protein farnesylation(GO:0018343)
17.4	34.7	GO:0009826	unidimensional cell growth(GO:0009826)
17.3	34.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
17.3	138.7	GO:0009437	carnitine metabolic process(GO:0009437)
17.3	69.3	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
17.3	121.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
17.3	51.9	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
17.2	17.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
17.2	68.7	GO:0046292	formaldehyde metabolic process(GO:0046292)
17.2	34.3	GO:0001543	ovarian follicle rupture(GO:0001543)
17.2	17.2	GO:1904688	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
17.1	119.8	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
17.0	34.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
17.0	102.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
17.0	51.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
17.0	33.9	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
16.9	50.8	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
16.9	33.8	GO:0006007	glucose catabolic process(GO:0006007)
16.9	253.7	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
16.9	67.6	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
16.9	16.9	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
16.8	84.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
16.8	16.8	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
16.8	151.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
16.8	33.6	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
16.8	33.6	GO:0099558	maintenance of synapse structure(GO:0099558)
16.8	16.8	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
16.8	16.8	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
16.8	50.3	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
16.7	16.7	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
16.7	50.1	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
16.7	33.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
16.7	50.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
16.7	133.5	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
16.7	33.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
16.6	33.2	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
16.6	49.8	GO:0090085	regulation of protein deubiquitination(GO:0090085)
16.5	49.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
16.4	32.9	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
16.4	196.6	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
16.4	98.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
16.3	49.0	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
16.3	81.6	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
16.3	81.5	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
16.3	179.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
16.3	16.3	GO:0009648	photoperiodism(GO:0009648)
16.3	65.0	GO:0060770	regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
16.2	16.2	GO:0003383	apical constriction(GO:0003383)
16.2	16.2	GO:0055089	fatty acid homeostasis(GO:0055089)
16.2	32.5	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
16.2	97.4	GO:0043173	nucleotide salvage(GO:0043173)
16.2	242.9	GO:0035767	endothelial cell chemotaxis(GO:0035767)
16.2	97.0	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
16.1	64.5	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
16.1	48.2	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
16.0	16.0	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
16.0	47.9	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
16.0	31.9	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
15.9	175.2	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
15.9	79.5	GO:1901563	response to camptothecin(GO:1901563)
15.8	79.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
15.8	47.5	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
15.8	47.5	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
15.8	15.8	GO:0042474	middle ear morphogenesis(GO:0042474)
15.8	110.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
15.8	15.8	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
15.8	110.3	GO:0032782	bile acid secretion(GO:0032782)
15.7	110.2	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
15.7	31.4	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
15.7	15.7	GO:0018214	protein carboxylation(GO:0018214)
15.6	15.6	GO:0072698	protein localization to microtubule cytoskeleton(GO:0072698)
15.6	62.5	GO:0072675	osteoclast fusion(GO:0072675)
15.6	77.9	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
15.6	124.5	GO:0009299	mRNA transcription(GO:0009299)
15.6	46.7	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
15.5	15.5	GO:0051775	response to redox state(GO:0051775)
15.5	155.3	GO:0002115	store-operated calcium entry(GO:0002115)
15.5	93.2	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
15.5	232.9	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
15.5	46.5	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
15.5	31.0	GO:0048549	positive regulation of pinocytosis(GO:0048549)
15.5	15.5	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
15.4	92.6	GO:0010216	maintenance of DNA methylation(GO:0010216)
15.4	46.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
15.4	76.8	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
15.3	30.7	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
15.3	45.9	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
15.3	15.3	GO:0061144	alveolar secondary septum development(GO:0061144)
15.2	15.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
15.2	15.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
15.2	15.2	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
15.2	167.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
15.2	45.6	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
15.2	45.5	GO:0016554	cytidine to uridine editing(GO:0016554)
15.2	15.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
15.2	90.9	GO:0045332	phospholipid translocation(GO:0045332)
15.1	15.1	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
15.1	45.4	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
15.1	75.7	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235)
15.1	15.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
15.1	136.1	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
15.1	60.4	GO:0018101	protein citrullination(GO:0018101)
15.1	60.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
15.0	45.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
15.0	691.4	GO:0007569	cell aging(GO:0007569)
15.0	45.1	GO:0016576	histone dephosphorylation(GO:0016576)
15.0	29.9	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
15.0	15.0	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
15.0	44.9	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
14.9	44.8	GO:0060487	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
14.9	74.7	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
14.9	89.6	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
14.9	59.5	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
14.9	29.7	GO:0061084	negative regulation of protein refolding(GO:0061084)
14.8	29.7	GO:0043379	memory T cell differentiation(GO:0043379)
14.8	29.6	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
14.8	14.8	GO:0006549	isoleucine metabolic process(GO:0006549)
14.8	132.8	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
14.7	117.7	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
14.7	14.7	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
14.7	14.7	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
14.7	44.0	GO:0006449	regulation of translational termination(GO:0006449)
14.7	146.6	GO:0001731	formation of translation preinitiation complex(GO:0001731)
14.6	43.9	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
14.6	73.1	GO:0001866	NK T cell proliferation(GO:0001866)
14.6	58.3	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
14.6	43.7	GO:0045218	zonula adherens maintenance(GO:0045218)
14.6	72.9	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
14.6	14.6	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
14.6	363.9	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
14.6	189.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
14.5	58.2	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
14.5	145.4	GO:0032060	bleb assembly(GO:0032060)
14.5	57.9	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
14.5	115.8	GO:0071361	cellular response to ethanol(GO:0071361)
14.5	72.4	GO:1903671	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
14.5	43.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
14.5	72.3	GO:0072537	fibroblast activation(GO:0072537)
14.4	14.4	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
14.4	43.3	GO:0015705	iodide transport(GO:0015705)
14.4	43.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
14.4	14.4	GO:0034204	lipid translocation(GO:0034204)
14.4	28.9	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
14.4	14.4	GO:0006901	vesicle coating(GO:0006901)
14.4	14.4	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
14.4	28.7	GO:0046487	glyoxylate metabolic process(GO:0046487)
14.3	28.7	GO:1903416	response to glycoside(GO:1903416)
14.3	42.9	GO:0015819	lysine transport(GO:0015819)
14.3	14.3	GO:0061511	centriole elongation(GO:0061511)
14.3	42.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
14.3	57.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
14.3	28.5	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
14.3	114.1	GO:0021670	lateral ventricle development(GO:0021670)
14.3	85.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
14.3	85.6	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
14.2	71.1	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
14.2	56.8	GO:0006083	acetate metabolic process(GO:0006083)
14.2	113.7	GO:0071218	cellular response to misfolded protein(GO:0071218)
14.2	142.0	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
14.2	42.5	GO:0000305	response to oxygen radical(GO:0000305)
14.2	56.7	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
14.2	85.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
14.1	42.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
14.1	183.8	GO:0045116	protein neddylation(GO:0045116)
14.1	70.6	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
14.1	112.9	GO:0000042	protein targeting to Golgi(GO:0000042)
14.1	14.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
14.1	28.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
14.1	42.2	GO:0034214	protein hexamerization(GO:0034214)
14.1	28.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
14.0	28.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
14.0	84.2	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
14.0	70.1	GO:0097421	liver regeneration(GO:0097421)
14.0	42.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
14.0	70.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
14.0	70.0	GO:0050779	RNA destabilization(GO:0050779)
14.0	42.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
14.0	14.0	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
14.0	14.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
13.9	55.7	GO:0032020	ISG15-protein conjugation(GO:0032020)
13.9	83.3	GO:0036010	protein localization to endosome(GO:0036010)
13.9	41.6	GO:0061043	regulation of vascular wound healing(GO:0061043)
13.9	97.0	GO:0051014	actin filament severing(GO:0051014)
13.9	41.6	GO:0019374	galactolipid metabolic process(GO:0019374)
13.8	110.6	GO:0008343	adult feeding behavior(GO:0008343)
13.8	69.0	GO:0046874	quinolinate metabolic process(GO:0046874)
13.8	41.4	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
13.8	41.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
13.8	275.3	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
13.8	55.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
13.8	302.6	GO:2000785	regulation of autophagosome assembly(GO:2000785)
13.7	13.7	GO:0071468	cellular response to acidic pH(GO:0071468)
13.7	178.6	GO:0006144	purine nucleobase metabolic process(GO:0006144)
13.7	109.5	GO:0060712	spongiotrophoblast layer development(GO:0060712)
13.7	109.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
13.7	355.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
13.7	273.3	GO:0014823	response to activity(GO:0014823)
13.7	41.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
13.6	81.7	GO:0019985	translesion synthesis(GO:0019985)
13.6	13.6	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
13.6	122.2	GO:0001893	maternal placenta development(GO:0001893)
13.6	40.7	GO:0006481	C-terminal protein methylation(GO:0006481)
13.6	54.3	GO:0070459	prolactin secretion(GO:0070459)
13.6	285.0	GO:0000186	activation of MAPKK activity(GO:0000186)
13.6	162.8	GO:0007076	mitotic chromosome condensation(GO:0007076)
13.5	40.5	GO:0071896	protein localization to adherens junction(GO:0071896)
13.5	54.0	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929)
13.5	13.5	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
13.5	67.4	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
13.5	53.9	GO:0006004	fucose metabolic process(GO:0006004)
13.5	13.5	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
13.5	13.5	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
13.5	13.5	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
13.5	53.8	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
13.4	80.6	GO:0070254	mucus secretion(GO:0070254)
13.4	134.2	GO:0018904	ether metabolic process(GO:0018904)
13.4	40.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
13.4	26.8	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
13.4	40.1	GO:0072697	protein localization to cell cortex(GO:0072697)
13.4	40.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
13.3	13.3	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
13.3	240.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
13.3	53.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
13.3	53.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
13.3	26.5	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
13.3	26.5	GO:0072718	response to cisplatin(GO:0072718)
13.3	13.3	GO:0060068	vagina development(GO:0060068)
13.3	39.8	GO:0031584	activation of phospholipase D activity(GO:0031584)
13.2	237.7	GO:0050873	brown fat cell differentiation(GO:0050873)
13.2	92.4	GO:0046040	IMP metabolic process(GO:0046040)
13.2	92.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
13.2	39.6	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
13.2	13.2	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
13.2	65.9	GO:0030033	microvillus assembly(GO:0030033)
13.2	26.3	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
13.2	52.7	GO:0021590	cerebellum maturation(GO:0021590)
13.2	52.6	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
13.1	302.3	GO:0043297	apical junction assembly(GO:0043297)
13.1	26.3	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
13.1	39.4	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
13.1	236.4	GO:0016578	histone deubiquitination(GO:0016578)
13.1	52.5	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
13.1	26.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
13.1	91.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
13.1	52.3	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
13.1	195.8	GO:0031648	protein destabilization(GO:0031648)
13.0	143.1	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
13.0	26.0	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
13.0	51.8	GO:0033623	regulation of integrin activation(GO:0033623)
12.9	77.7	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
12.9	103.4	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
12.9	25.8	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
12.9	38.6	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
12.8	12.8	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
12.8	51.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
12.8	25.6	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
12.8	25.6	GO:0010387	COP9 signalosome assembly(GO:0010387)
12.8	102.4	GO:0051383	kinetochore organization(GO:0051383)
12.8	12.8	GO:0098792	xenophagy(GO:0098792)
12.8	12.8	GO:0048539	bone marrow development(GO:0048539)
12.8	25.5	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
12.8	76.6	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
12.8	25.5	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
12.7	63.7	GO:0032486	Rap protein signal transduction(GO:0032486)
12.7	101.9	GO:0009313	oligosaccharide catabolic process(GO:0009313)
12.7	165.3	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
12.7	38.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
12.7	76.1	GO:0008298	intracellular mRNA localization(GO:0008298)
12.6	25.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
12.6	37.7	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
12.5	37.6	GO:0021698	cerebellar cortex structural organization(GO:0021698)
12.5	62.4	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
12.5	49.9	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
12.5	24.9	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
12.4	124.4	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
12.4	24.8	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
12.4	49.6	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
12.4	37.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
12.4	74.1	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
12.4	98.8	GO:0042770	signal transduction in response to DNA damage(GO:0042770)
12.3	12.3	GO:0016584	nucleosome positioning(GO:0016584)
12.3	12.3	GO:0019377	glycolipid catabolic process(GO:0019377)
12.3	61.6	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
12.3	12.3	GO:0007143	female meiotic division(GO:0007143)
12.3	12.3	GO:0001803	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
12.3	24.6	GO:0010040	response to iron(II) ion(GO:0010040)
12.3	85.9	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
12.3	85.9	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
12.3	196.2	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
12.2	97.9	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
12.2	12.2	GO:0071639	positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
12.2	97.6	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
12.2	12.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
12.2	12.2	GO:0042559	tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
12.2	12.2	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
12.1	12.1	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
12.1	24.3	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
12.1	36.3	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)
12.1	24.2	GO:0018158	protein oxidation(GO:0018158)
12.1	84.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
12.1	24.2	GO:0071895	odontoblast differentiation(GO:0071895)
12.1	36.2	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
12.1	24.2	GO:0060263	regulation of respiratory burst(GO:0060263) positive regulation of respiratory burst(GO:0060267)
12.1	60.3	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
12.1	229.0	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
12.0	36.1	GO:0015886	heme transport(GO:0015886)
12.0	48.2	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
12.0	240.7	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
12.0	24.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
12.0	60.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
12.0	12.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
12.0	24.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
12.0	36.0	GO:0097284	hepatocyte apoptotic process(GO:0097284)
12.0	23.9	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
11.9	71.7	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
11.9	143.2	GO:0010508	positive regulation of autophagy(GO:0010508)
11.9	95.4	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
11.9	47.5	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
11.9	23.7	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
11.8	130.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
11.8	177.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
11.8	35.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
11.8	82.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
11.8	58.8	GO:0045793	positive regulation of cell size(GO:0045793)
11.8	23.5	GO:0006907	pinocytosis(GO:0006907)
11.8	47.0	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
11.7	11.7	GO:1901970	positive regulation of mitotic sister chromatid separation(GO:1901970)
11.7	11.7	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
11.7	58.6	GO:0030953	astral microtubule organization(GO:0030953)
11.7	23.4	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
11.7	140.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
11.7	256.8	GO:0032922	circadian regulation of gene expression(GO:0032922)
11.7	11.7	GO:0032286	central nervous system myelin maintenance(GO:0032286)
11.7	46.7	GO:0031929	TOR signaling(GO:0031929)
11.6	23.3	GO:0003281	ventricular septum development(GO:0003281)
11.6	162.8	GO:0016239	positive regulation of macroautophagy(GO:0016239)
11.6	151.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
11.6	34.9	GO:0006287	base-excision repair, gap-filling(GO:0006287)
11.6	23.2	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
11.6	23.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
11.6	11.6	GO:0003162	atrioventricular node development(GO:0003162)
11.6	34.8	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
11.5	11.5	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
11.5	23.1	GO:0016259	selenocysteine metabolic process(GO:0016259)
11.5	34.6	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
11.5	23.0	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
11.5	11.5	GO:2000468	regulation of peroxidase activity(GO:2000468)
11.5	103.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
11.5	11.5	GO:0060631	regulation of meiosis I(GO:0060631) positive regulation of meiosis I(GO:0060903)
11.5	57.4	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
11.5	34.4	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
11.5	91.7	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
11.4	22.9	GO:0015755	fructose transport(GO:0015755)
11.4	45.6	GO:0002636	positive regulation of germinal center formation(GO:0002636)
11.4	22.8	GO:0030223	neutrophil differentiation(GO:0030223)
11.4	34.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
11.4	34.1	GO:1900363	regulation of mRNA polyadenylation(GO:1900363) negative regulation of mRNA polyadenylation(GO:1900364)
11.4	22.7	GO:1904705	regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874)
11.4	22.7	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
11.4	56.8	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
11.3	22.7	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
11.3	11.3	GO:0030574	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
11.3	33.9	GO:0043921	modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
11.3	11.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
11.3	11.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
11.3	11.3	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
11.3	101.5	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
11.2	56.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
11.2	22.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
11.2	33.6	GO:0000052	citrulline metabolic process(GO:0000052)
11.2	11.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
11.2	201.2	GO:0006308	DNA catabolic process(GO:0006308)
11.2	11.2	GO:0006551	leucine metabolic process(GO:0006551)
11.2	55.8	GO:0031053	primary miRNA processing(GO:0031053)
11.1	66.9	GO:0071803	positive regulation of podosome assembly(GO:0071803)
11.1	11.1	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
11.1	11.1	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
11.1	22.3	GO:0061045	negative regulation of wound healing(GO:0061045)
11.1	33.4	GO:0032148	activation of protein kinase B activity(GO:0032148)
11.1	55.6	GO:0006561	proline biosynthetic process(GO:0006561)
11.1	22.1	GO:0045923	positive regulation of fatty acid metabolic process(GO:0045923)
11.1	22.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
11.0	44.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
11.0	44.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
11.0	11.0	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
11.0	21.9	GO:0006600	creatine metabolic process(GO:0006600)
11.0	32.9	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
10.9	43.8	GO:0051292	nuclear pore complex assembly(GO:0051292)
10.9	360.4	GO:0032006	regulation of TOR signaling(GO:0032006)
10.9	43.7	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
10.9	10.9	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
10.9	32.7	GO:0001555	oocyte growth(GO:0001555)
10.9	239.7	GO:0008286	insulin receptor signaling pathway(GO:0008286)
10.9	21.8	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
10.9	10.9	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
10.8	21.7	GO:0019042	viral latency(GO:0019042)
10.8	10.8	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
10.8	21.7	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
10.8	10.8	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
10.8	21.6	GO:0060056	mammary gland involution(GO:0060056)
10.8	64.7	GO:0007379	segment specification(GO:0007379)
10.8	32.3	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
10.8	43.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
10.8	86.1	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
10.8	32.3	GO:0035019	somatic stem cell population maintenance(GO:0035019)
10.7	42.9	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
10.7	53.6	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
10.7	96.3	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
10.7	42.7	GO:0036233	glycine import(GO:0036233)
10.7	53.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
10.6	63.9	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
10.6	10.6	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
10.6	31.8	GO:0009838	abscission(GO:0009838)
10.6	21.2	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
10.6	63.5	GO:0061615	glycolytic process through fructose-6-phosphate(GO:0061615)
10.6	42.3	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
10.6	10.6	GO:0043129	surfactant homeostasis(GO:0043129)
10.5	21.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
10.5	221.3	GO:0018208	peptidyl-proline modification(GO:0018208)
10.5	21.1	GO:1903363	negative regulation of cellular protein catabolic process(GO:1903363)
10.5	105.1	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
10.5	21.0	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
10.5	52.5	GO:0034198	cellular response to amino acid starvation(GO:0034198)
10.5	21.0	GO:0071548	response to dexamethasone(GO:0071548)
10.5	20.9	GO:0055088	lipid homeostasis(GO:0055088)
10.5	31.4	GO:0010992	ubiquitin homeostasis(GO:0010992)
10.4	62.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
10.4	10.4	GO:0045820	negative regulation of glycolytic process(GO:0045820)
10.4	83.1	GO:1900027	regulation of ruffle assembly(GO:1900027)
10.4	62.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
10.4	62.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
10.4	20.7	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
10.3	20.7	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
10.3	51.7	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
10.3	72.4	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
10.3	41.3	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
10.3	41.3	GO:0006824	cobalt ion transport(GO:0006824)
10.3	30.9	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
10.3	10.3	GO:0032596	protein transport into membrane raft(GO:0032596)
10.3	10.3	GO:0060155	platelet dense granule organization(GO:0060155)
10.3	10.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
10.2	133.2	GO:0048821	erythrocyte development(GO:0048821)
10.2	30.7	GO:0061042	vascular wound healing(GO:0061042)
10.2	317.3	GO:0006611	protein export from nucleus(GO:0006611)
10.2	40.9	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
10.2	10.2	GO:0009446	putrescine biosynthetic process(GO:0009446)
10.2	30.6	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
10.2	10.2	GO:1901859	regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
10.2	51.0	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
10.2	71.3	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
10.2	101.9	GO:0016574	histone ubiquitination(GO:0016574)
10.2	20.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
10.2	81.4	GO:0001833	inner cell mass cell proliferation(GO:0001833)
10.2	10.2	GO:0051660	establishment of centrosome localization(GO:0051660)
10.2	50.9	GO:0070475	rRNA base methylation(GO:0070475)
10.2	30.5	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
10.2	30.5	GO:0033572	transferrin transport(GO:0033572)
10.1	50.7	GO:0006572	tyrosine catabolic process(GO:0006572)
10.1	30.4	GO:1901419	regulation of response to alcohol(GO:1901419)
10.1	50.5	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
10.1	50.3	GO:0042168	heme metabolic process(GO:0042168)
10.1	20.1	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
10.0	20.0	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
10.0	10.0	GO:0042891	antibiotic transport(GO:0042891)
10.0	70.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
10.0	10.0	GO:0036089	cleavage furrow formation(GO:0036089)
10.0	19.9	GO:0035973	aggrephagy(GO:0035973)
10.0	10.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
9.9	29.8	GO:0034508	centromere complex assembly(GO:0034508)
9.9	248.4	GO:0043966	histone H3 acetylation(GO:0043966)
9.9	49.7	GO:0051026	chiasma assembly(GO:0051026)
9.9	9.9	GO:0061470	T follicular helper cell differentiation(GO:0061470)
9.9	49.6	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
9.9	29.7	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
9.9	39.5	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
9.9	39.5	GO:0009992	cellular water homeostasis(GO:0009992)
9.9	147.8	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
9.8	9.8	GO:0051182	coenzyme transport(GO:0051182)
9.8	19.7	GO:0032482	Rab protein signal transduction(GO:0032482)
9.8	58.9	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
9.8	19.6	GO:0048069	eye pigmentation(GO:0048069)
9.8	19.6	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
9.8	9.8	GO:0043084	penile erection(GO:0043084)
9.8	48.8	GO:0006569	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
9.7	9.7	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
9.7	19.4	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
9.7	155.5	GO:0034340	response to type I interferon(GO:0034340)
9.7	19.3	GO:0034720	histone H3-K4 demethylation(GO:0034720)
9.7	9.7	GO:1903525	regulation of membrane tubulation(GO:1903525)
9.6	125.4	GO:0016925	protein sumoylation(GO:0016925)
9.6	19.3	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
9.6	28.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
9.6	67.1	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
9.6	57.5	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
9.6	9.6	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
9.6	19.1	GO:0018022	peptidyl-lysine methylation(GO:0018022)
9.6	19.1	GO:0042989	sequestering of actin monomers(GO:0042989)
9.6	76.5	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
9.5	47.6	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
9.5	342.5	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
9.5	19.0	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
9.5	28.4	GO:0000032	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
9.4	9.4	GO:0032966	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966)
9.4	18.8	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
9.4	37.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
9.4	37.6	GO:0032570	response to progesterone(GO:0032570)
9.4	18.8	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
9.4	18.8	GO:0032769	negative regulation of monooxygenase activity(GO:0032769)
9.4	28.1	GO:0015871	choline transport(GO:0015871)
9.3	37.4	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
9.3	46.7	GO:0046037	GMP metabolic process(GO:0046037)
9.3	46.7	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
9.3	37.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
9.3	27.9	GO:0090156	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
9.3	111.8	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
9.3	37.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
9.3	9.3	GO:0035384	thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616)
9.3	83.6	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434)
9.3	27.8	GO:0006670	sphingosine metabolic process(GO:0006670)
9.3	18.5	GO:0043328	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
9.3	148.2	GO:0051865	protein autoubiquitination(GO:0051865)
9.3	27.8	GO:0032474	otolith morphogenesis(GO:0032474)
9.2	9.2	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
9.2	9.2	GO:0030421	defecation(GO:0030421)
9.2	9.2	GO:0015670	carbon dioxide transport(GO:0015670)
9.2	137.9	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
9.2	146.9	GO:0000469	cleavage involved in rRNA processing(GO:0000469)
9.2	36.7	GO:1904970	brush border assembly(GO:1904970)
9.2	18.3	GO:0051661	maintenance of centrosome location(GO:0051661)
9.2	36.6	GO:0018202	peptidyl-histidine modification(GO:0018202)
9.2	27.5	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
9.1	18.3	GO:0000966	RNA 5'-end processing(GO:0000966)
9.1	27.4	GO:0006116	NADH oxidation(GO:0006116)
9.1	54.8	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
9.1	73.0	GO:0030212	hyaluronan metabolic process(GO:0030212)
9.1	36.5	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
9.1	9.1	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
9.1	45.3	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
9.0	27.1	GO:0042732	D-xylose metabolic process(GO:0042732)
9.0	90.3	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
9.0	45.2	GO:0032675	regulation of interleukin-6 production(GO:0032675)
9.0	18.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
8.9	17.9	GO:0010815	bradykinin catabolic process(GO:0010815)
8.9	17.9	GO:0061450	trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
8.9	8.9	GO:0006545	glycine biosynthetic process(GO:0006545)
8.9	17.8	GO:0033119	negative regulation of RNA splicing(GO:0033119)
8.9	160.0	GO:0016180	snRNA processing(GO:0016180)
8.9	88.9	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
8.9	35.5	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
8.9	17.7	GO:0000183	chromatin silencing at rDNA(GO:0000183)
8.8	26.5	GO:0018094	protein polyglycylation(GO:0018094)
8.8	17.7	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
8.8	8.8	GO:0006532	aspartate biosynthetic process(GO:0006532)
8.8	44.2	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
8.8	52.8	GO:0006013	mannose metabolic process(GO:0006013)
8.8	96.7	GO:2000378	negative regulation of reactive oxygen species metabolic process(GO:2000378)
8.8	26.3	GO:0019086	late viral transcription(GO:0019086)
8.8	17.6	GO:0043490	malate-aspartate shuttle(GO:0043490)
8.8	26.3	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
8.8	52.6	GO:0031167	rRNA methylation(GO:0031167)
8.8	26.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
8.8	52.6	GO:0006098	pentose-phosphate shunt(GO:0006098)
8.8	17.5	GO:0042149	cellular response to glucose starvation(GO:0042149)
8.7	8.7	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
8.7	17.5	GO:0090201	negative regulation of release of cytochrome c from mitochondria(GO:0090201)
8.7	17.4	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
8.7	43.5	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
8.7	34.7	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
8.7	60.8	GO:0043954	cellular component maintenance(GO:0043954)
8.7	8.7	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
8.7	17.3	GO:0006577	amino-acid betaine metabolic process(GO:0006577)
8.7	34.6	GO:0043388	positive regulation of DNA binding(GO:0043388)
8.6	25.9	GO:0035066	positive regulation of histone acetylation(GO:0035066)
8.6	17.2	GO:0051782	negative regulation of cell division(GO:0051782)
8.6	68.7	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
8.6	34.3	GO:0031061	negative regulation of histone methylation(GO:0031061)
8.6	17.2	GO:0042373	vitamin K metabolic process(GO:0042373)
8.6	8.6	GO:1903333	negative regulation of protein folding(GO:1903333)
8.6	25.7	GO:0014883	transition between fast and slow fiber(GO:0014883)
8.5	8.5	GO:0010874	regulation of cholesterol efflux(GO:0010874)
8.5	17.0	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
8.5	8.5	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
8.5	8.5	GO:0044252	negative regulation of multicellular organismal metabolic process(GO:0044252)
8.5	76.2	GO:0015732	prostaglandin transport(GO:0015732)
8.5	42.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
8.5	236.8	GO:0006749	glutathione metabolic process(GO:0006749)
8.5	33.8	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
8.5	8.5	GO:0060157	urinary bladder development(GO:0060157)
8.4	565.1	GO:0008654	phospholipid biosynthetic process(GO:0008654)
8.4	33.7	GO:0070670	response to interleukin-4(GO:0070670)
8.4	185.2	GO:0034728	nucleosome organization(GO:0034728)
8.4	50.4	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
8.4	25.2	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
8.4	25.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
8.4	58.8	GO:0035493	SNARE complex assembly(GO:0035493)
8.4	25.2	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
8.4	25.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
8.4	8.4	GO:2000738	positive regulation of stem cell differentiation(GO:2000738)
8.4	175.8	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
8.4	8.4	GO:0071276	cellular response to cadmium ion(GO:0071276)
8.4	8.4	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
8.4	58.5	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
8.4	8.4	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
8.3	8.3	GO:0045176	apical protein localization(GO:0045176)
8.3	8.3	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
8.3	16.6	GO:0046112	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleobase biosynthetic process(GO:0046112)
8.3	16.6	GO:0060235	lens induction in camera-type eye(GO:0060235)
8.3	16.6	GO:0070268	cornification(GO:0070268)
8.3	16.6	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
8.3	58.0	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
8.3	16.5	GO:0055119	relaxation of cardiac muscle(GO:0055119)
8.3	8.3	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
8.2	24.7	GO:0010039	response to iron ion(GO:0010039)
8.2	8.2	GO:2000667	interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) positive regulation of interleukin-5 secretion(GO:2000664) regulation of interleukin-13 secretion(GO:2000665) positive regulation of interleukin-13 secretion(GO:2000667)
8.2	33.0	GO:0006102	isocitrate metabolic process(GO:0006102)
8.2	8.2	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
8.2	49.2	GO:0070986	left/right axis specification(GO:0070986)
8.2	8.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
8.2	89.8	GO:0071479	cellular response to ionizing radiation(GO:0071479)
8.2	8.2	GO:1901856	negative regulation of cellular respiration(GO:1901856)
8.1	24.4	GO:0046951	ketone body biosynthetic process(GO:0046951)
8.1	40.7	GO:0033136	serine phosphorylation of STAT3 protein(GO:0033136)
8.1	16.3	GO:0032594	protein transport within lipid bilayer(GO:0032594)
8.1	65.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
8.1	24.4	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
8.1	24.4	GO:0030149	sphingolipid catabolic process(GO:0030149)
8.1	8.1	GO:1904181	positive regulation of membrane depolarization(GO:1904181)
8.1	24.3	GO:0032642	regulation of chemokine production(GO:0032642)
8.1	16.2	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
8.1	16.1	GO:1904424	regulation of GTP binding(GO:1904424)
8.1	16.1	GO:1903998	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
8.1	8.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
8.0	24.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
8.0	40.2	GO:0010459	negative regulation of heart rate(GO:0010459)
8.0	32.1	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
8.0	16.0	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
8.0	8.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
8.0	32.0	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
8.0	24.0	GO:0032099	negative regulation of appetite(GO:0032099)
8.0	120.0	GO:0097194	execution phase of apoptosis(GO:0097194)
8.0	8.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
8.0	16.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
8.0	32.0	GO:0071800	podosome assembly(GO:0071800)
8.0	71.8	GO:0010960	magnesium ion homeostasis(GO:0010960)
8.0	31.9	GO:0043312	neutrophil degranulation(GO:0043312)
8.0	63.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
8.0	23.9	GO:0016572	histone phosphorylation(GO:0016572)
8.0	8.0	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501) regulation of hemoglobin biosynthetic process(GO:0046984)
7.9	55.6	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
7.9	23.8	GO:0006301	postreplication repair(GO:0006301)
7.9	23.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
7.9	23.8	GO:0050884	neuromuscular process controlling posture(GO:0050884)
7.9	23.7	GO:0001556	oocyte maturation(GO:0001556)
7.9	31.6	GO:2000641	regulation of early endosome to late endosome transport(GO:2000641)
7.9	15.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
7.9	15.8	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
7.9	86.9	GO:0051601	exocyst localization(GO:0051601)
7.9	23.6	GO:0045740	positive regulation of DNA replication(GO:0045740)
7.9	63.0	GO:0048535	lymph node development(GO:0048535)
7.9	94.5	GO:0021591	ventricular system development(GO:0021591)
7.9	189.0	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
7.9	31.4	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
7.8	15.6	GO:0010212	response to ionizing radiation(GO:0010212)
7.8	7.8	GO:0032108	negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
7.8	23.4	GO:0020027	hemoglobin metabolic process(GO:0020027)
7.8	23.3	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
7.8	15.6	GO:0042506	tyrosine phosphorylation of Stat5 protein(GO:0042506)
7.8	7.8	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
7.8	31.1	GO:0003356	regulation of cilium beat frequency(GO:0003356)
7.8	38.8	GO:1901070	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) guanosine-containing compound biosynthetic process(GO:1901070)
7.8	31.1	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
7.8	31.0	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
7.8	69.8	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
7.7	46.5	GO:0000729	DNA double-strand break processing(GO:0000729)
7.7	7.7	GO:0043620	regulation of DNA-templated transcription in response to stress(GO:0043620)
7.7	30.9	GO:0070126	mitochondrial translational termination(GO:0070126)
7.7	7.7	GO:1901662	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
7.7	69.3	GO:0051492	regulation of stress fiber assembly(GO:0051492)
7.7	15.4	GO:0015936	coenzyme A metabolic process(GO:0015936)
7.7	53.8	GO:0051568	histone H3-K4 methylation(GO:0051568)
7.7	7.7	GO:0001887	selenium compound metabolic process(GO:0001887)
7.7	7.7	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
7.6	22.9	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239)
7.6	15.3	GO:1904938	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
7.6	152.3	GO:0006338	chromatin remodeling(GO:0006338)
7.6	7.6	GO:0046036	CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
7.6	7.6	GO:0071321	cellular response to cGMP(GO:0071321)
7.6	15.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
7.6	53.2	GO:0055090	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
7.6	15.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
7.6	15.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
7.6	121.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
7.6	15.2	GO:0034587	piRNA metabolic process(GO:0034587)
7.6	7.6	GO:2000823	regulation of androgen receptor activity(GO:2000823)
7.5	37.7	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
7.5	15.1	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
7.5	203.6	GO:0065002	intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
7.5	22.6	GO:0006742	NADP catabolic process(GO:0006742)
7.5	7.5	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
7.5	37.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
7.5	15.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
7.5	171.9	GO:0016126	sterol biosynthetic process(GO:0016126)
7.5	14.9	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
7.5	238.6	GO:0090630	activation of GTPase activity(GO:0090630)
7.4	44.7	GO:0060009	Sertoli cell development(GO:0060009)
7.4	22.3	GO:0032965	regulation of collagen biosynthetic process(GO:0032965)
7.4	22.3	GO:0090527	actin filament reorganization(GO:0090527)
7.4	14.9	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
7.4	66.8	GO:0007062	sister chromatid cohesion(GO:0007062)
7.4	14.8	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
7.4	7.4	GO:0008053	mitochondrial fusion(GO:0008053)
7.4	51.8	GO:0015858	nucleoside transport(GO:0015858)
7.4	7.4	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
7.4	177.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
7.4	7.4	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
7.4	29.5	GO:0048739	cardiac muscle fiber development(GO:0048739)
7.4	22.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
7.4	7.4	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
7.4	14.7	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
7.4	36.8	GO:0046599	regulation of centriole replication(GO:0046599)
7.4	14.7	GO:0015889	cobalamin transport(GO:0015889)
7.3	73.4	GO:0070208	protein heterotrimerization(GO:0070208)
7.3	14.6	GO:0070189	kynurenine metabolic process(GO:0070189)
7.3	43.9	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
7.3	7.3	GO:0006667	sphinganine metabolic process(GO:0006667)
7.3	72.9	GO:0043968	histone H2A acetylation(GO:0043968)
7.3	43.7	GO:0018065	protein-cofactor linkage(GO:0018065)
7.3	21.8	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
7.2	29.0	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
7.2	224.3	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
7.2	65.1	GO:0060674	placenta blood vessel development(GO:0060674)
7.2	21.7	GO:0051785	positive regulation of nuclear division(GO:0051785)
7.2	36.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
7.2	57.6	GO:0016926	protein desumoylation(GO:0016926)
7.2	14.4	GO:0006068	ethanol catabolic process(GO:0006068)
7.2	28.6	GO:0007100	mitotic centrosome separation(GO:0007100)
7.2	28.6	GO:0007252	I-kappaB phosphorylation(GO:0007252)
7.2	14.3	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
7.1	14.3	GO:0006691	leukotriene metabolic process(GO:0006691)
7.1	28.6	GO:0014043	negative regulation of neuron maturation(GO:0014043)
7.1	14.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
7.1	14.3	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
7.1	21.4	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
7.1	78.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
7.1	71.2	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
7.1	35.5	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
7.1	28.4	GO:0009404	toxin metabolic process(GO:0009404)
7.1	21.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
7.1	42.4	GO:0050931	pigment cell differentiation(GO:0050931)
7.1	84.7	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
7.1	14.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
7.0	70.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
7.0	21.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
7.0	28.1	GO:0046686	response to cadmium ion(GO:0046686)
7.0	63.3	GO:0030049	muscle filament sliding(GO:0030049)
7.0	175.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
7.0	28.1	GO:0042737	drug catabolic process(GO:0042737)
7.0	7.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
7.0	63.0	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
7.0	41.9	GO:0051084	'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
7.0	188.2	GO:1901800	positive regulation of proteasomal protein catabolic process(GO:1901800)
7.0	7.0	GO:0060931	sinoatrial node cell development(GO:0060931)
7.0	62.6	GO:0043206	extracellular fibril organization(GO:0043206)
7.0	69.5	GO:0006896	Golgi to vacuole transport(GO:0006896)
6.9	13.9	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
6.9	41.7	GO:0030449	regulation of complement activation(GO:0030449)
6.9	27.7	GO:0033227	dsRNA transport(GO:0033227)
6.9	34.6	GO:0006903	vesicle targeting(GO:0006903)
6.9	41.5	GO:0046039	GTP metabolic process(GO:0046039)
6.9	20.7	GO:0002457	T cell antigen processing and presentation(GO:0002457)
6.9	55.1	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
6.9	110.2	GO:0030218	erythrocyte differentiation(GO:0030218)
6.9	6.9	GO:0002036	regulation of L-glutamate transport(GO:0002036)
6.9	27.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
6.9	13.7	GO:0043101	purine-containing compound salvage(GO:0043101)
6.9	102.9	GO:0000266	mitochondrial fission(GO:0000266)
6.9	6.9	GO:0072663	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
6.8	20.5	GO:0009629	response to gravity(GO:0009629)
6.8	34.1	GO:0042448	progesterone metabolic process(GO:0042448)
6.8	34.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
6.8	13.6	GO:0018206	peptidyl-methionine modification(GO:0018206)
6.8	13.6	GO:0006298	mismatch repair(GO:0006298)
6.8	13.6	GO:0045351	type I interferon biosynthetic process(GO:0045351)
6.8	20.3	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
6.8	20.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
6.8	6.8	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
6.8	6.8	GO:0043504	mitochondrial DNA repair(GO:0043504)
6.7	27.0	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
6.7	6.7	GO:0034032	nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032)
6.7	6.7	GO:0060539	diaphragm development(GO:0060539)
6.7	87.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
6.7	13.4	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
6.7	53.6	GO:1903146	regulation of mitophagy(GO:1903146)
6.7	6.7	GO:0050892	intestinal absorption(GO:0050892)
6.7	33.4	GO:0034629	cellular protein complex localization(GO:0034629)
6.7	13.4	GO:0033327	Leydig cell differentiation(GO:0033327)
6.7	46.7	GO:0072678	T cell migration(GO:0072678)
6.7	46.6	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
6.6	6.6	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
6.6	19.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
6.6	26.5	GO:0006855	drug transmembrane transport(GO:0006855)
6.6	26.5	GO:0014888	striated muscle adaptation(GO:0014888)
6.6	86.1	GO:0016575	histone deacetylation(GO:0016575)
6.6	6.6	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
6.6	19.8	GO:0070542	response to fatty acid(GO:0070542)
6.6	72.5	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
6.6	6.6	GO:2000756	regulation of peptidyl-lysine acetylation(GO:2000756)
6.6	46.1	GO:0006353	DNA-templated transcription, termination(GO:0006353)
6.6	6.6	GO:1901096	regulation of autophagosome maturation(GO:1901096)
6.6	6.6	GO:0002314	germinal center B cell differentiation(GO:0002314)
6.6	6.6	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
6.5	6.5	GO:0014841	skeletal muscle satellite cell proliferation(GO:0014841)
6.5	6.5	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
6.5	97.9	GO:0006801	superoxide metabolic process(GO:0006801)
6.5	39.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
6.5	58.6	GO:0001706	endoderm formation(GO:0001706)
6.5	65.0	GO:0001675	acrosome assembly(GO:0001675)
6.5	13.0	GO:0060613	fat pad development(GO:0060613)
6.5	6.5	GO:0035799	ureter maturation(GO:0035799)
6.5	13.0	GO:0046185	aldehyde catabolic process(GO:0046185)
6.5	32.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
6.5	6.5	GO:0016073	snRNA metabolic process(GO:0016073)
6.5	12.9	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
6.5	12.9	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
6.5	71.1	GO:0048753	pigment granule organization(GO:0048753)
6.4	12.9	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
6.4	32.1	GO:0043405	regulation of MAP kinase activity(GO:0043405)
6.4	25.6	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
6.4	12.8	GO:0071850	mitotic cell cycle arrest(GO:0071850)
6.4	51.1	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
6.4	31.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
6.4	19.1	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
6.3	272.2	GO:0051028	mRNA transport(GO:0051028)
6.3	6.3	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
6.3	18.9	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
6.3	6.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
6.3	6.3	GO:0033004	negative regulation of mast cell activation(GO:0033004)
6.3	44.1	GO:0006817	phosphate ion transport(GO:0006817)
6.3	25.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
6.3	6.3	GO:0040033	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
6.3	25.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
6.3	6.3	GO:0021569	rhombomere 3 development(GO:0021569)
6.3	12.5	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
6.3	37.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
6.3	6.3	GO:0006167	AMP biosynthetic process(GO:0006167)
6.3	219.3	GO:0006633	fatty acid biosynthetic process(GO:0006633)
6.3	43.8	GO:0071824	protein-DNA complex subunit organization(GO:0071824)
6.3	6.3	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
6.2	31.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
6.2	136.7	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
6.2	18.6	GO:0034101	erythrocyte homeostasis(GO:0034101)
6.2	6.2	GO:0071467	cellular response to pH(GO:0071467)
6.2	24.8	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
6.2	18.5	GO:0070125	mitochondrial translational elongation(GO:0070125)
6.2	86.5	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
6.2	104.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
6.2	18.5	GO:0006525	arginine metabolic process(GO:0006525)
6.1	24.6	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
6.1	6.1	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
6.1	12.2	GO:0072224	metanephric glomerulus development(GO:0072224)
6.1	12.2	GO:2000811	negative regulation of anoikis(GO:2000811)
6.1	12.2	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
6.1	61.0	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
6.1	18.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
6.1	12.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
6.1	12.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
6.1	103.3	GO:0006641	triglyceride metabolic process(GO:0006641)
6.1	12.1	GO:0006868	glutamine transport(GO:0006868)
6.1	36.3	GO:0036159	inner dynein arm assembly(GO:0036159)
6.0	78.5	GO:0051168	nuclear export(GO:0051168)
6.0	30.2	GO:0006528	asparagine metabolic process(GO:0006528)
6.0	42.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
6.0	12.0	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
6.0	12.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
6.0	54.0	GO:0008340	determination of adult lifespan(GO:0008340)
6.0	12.0	GO:1903887	motile primary cilium assembly(GO:1903887)
6.0	30.0	GO:0071711	basement membrane organization(GO:0071711)
5.9	17.8	GO:0036035	osteoclast development(GO:0036035)
5.9	5.9	GO:0048865	stem cell fate commitment(GO:0048865)
5.9	11.8	GO:0048148	behavioral response to cocaine(GO:0048148)
5.9	11.8	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
5.9	23.6	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
5.9	47.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
5.9	29.5	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
5.9	11.8	GO:0015697	quaternary ammonium group transport(GO:0015697)
5.9	135.8	GO:0018345	protein palmitoylation(GO:0018345)
5.9	11.8	GO:0031268	pseudopodium organization(GO:0031268)
5.9	5.9	GO:0006415	translational termination(GO:0006415)
5.9	410.9	GO:0016568	chromatin modification(GO:0016568)
5.9	23.5	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
5.9	445.9	GO:0007266	Rho protein signal transduction(GO:0007266)
5.9	17.6	GO:0015671	oxygen transport(GO:0015671)
5.9	5.9	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
5.9	17.6	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
5.8	5.8	GO:0022011	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
5.8	5.8	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
5.8	5.8	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
5.8	17.5	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
5.8	17.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
5.8	86.9	GO:0000045	autophagosome assembly(GO:0000045)
5.8	63.5	GO:0017144	drug metabolic process(GO:0017144)
5.8	17.3	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
5.7	74.7	GO:0019319	hexose biosynthetic process(GO:0019319)
5.7	5.7	GO:0045324	late endosome to vacuole transport(GO:0045324)
5.7	51.6	GO:0007099	centriole replication(GO:0007099)
5.7	5.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
5.7	17.2	GO:0044346	fibroblast apoptotic process(GO:0044346) regulation of fibroblast apoptotic process(GO:2000269)
5.7	5.7	GO:0097212	lysosomal membrane organization(GO:0097212)
5.7	28.5	GO:0071318	cellular response to ATP(GO:0071318)
5.7	17.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
5.7	11.4	GO:0002576	platelet degranulation(GO:0002576)
5.7	11.4	GO:0048368	lateral mesoderm development(GO:0048368)
5.7	5.7	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
5.7	17.0	GO:0010225	response to UV-C(GO:0010225)
5.7	62.3	GO:0045682	regulation of epidermis development(GO:0045682)
5.7	11.3	GO:1902652	secondary alcohol metabolic process(GO:1902652)
5.7	17.0	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
5.7	56.6	GO:0042730	fibrinolysis(GO:0042730)
5.7	17.0	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
5.6	16.9	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
5.6	28.2	GO:0046415	urate metabolic process(GO:0046415)
5.6	22.5	GO:0016264	gap junction assembly(GO:0016264)
5.6	95.6	GO:0006730	one-carbon metabolic process(GO:0006730)
5.6	5.6	GO:1902306	negative regulation of sodium ion transmembrane transport(GO:1902306)
5.6	16.8	GO:0030202	heparin metabolic process(GO:0030202)
5.6	72.8	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
5.6	28.0	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
5.6	295.7	GO:0007051	spindle organization(GO:0007051)
5.6	5.6	GO:0007031	peroxisome organization(GO:0007031)
5.6	22.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
5.5	11.1	GO:0007585	respiratory gaseous exchange(GO:0007585)
5.5	11.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
5.5	11.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
5.5	88.3	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
5.5	27.6	GO:0000103	sulfate assimilation(GO:0000103)
5.5	16.5	GO:0019482	beta-alanine metabolic process(GO:0019482)
5.5	16.5	GO:1990776	cellular response to angiotensin(GO:1904385) response to angiotensin(GO:1990776)
5.5	22.0	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
5.5	5.5	GO:0030242	pexophagy(GO:0030242)
5.5	16.5	GO:0042026	protein refolding(GO:0042026)
5.5	27.4	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
5.5	5.5	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
5.5	16.4	GO:0090025	regulation of monocyte chemotaxis(GO:0090025)
5.5	21.8	GO:0007000	nucleolus organization(GO:0007000)
5.5	10.9	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
5.4	5.4	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
5.4	5.4	GO:0015817	histidine transport(GO:0015817)
5.4	16.2	GO:0031054	pre-miRNA processing(GO:0031054)
5.4	16.2	GO:0045838	positive regulation of membrane potential(GO:0045838)
5.4	32.3	GO:0072528	pyrimidine-containing compound biosynthetic process(GO:0072528)
5.4	37.6	GO:0042632	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
5.4	75.2	GO:0001522	pseudouridine synthesis(GO:0001522)
5.4	5.4	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
5.4	21.4	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
5.3	21.4	GO:0034227	tRNA thio-modification(GO:0034227)
5.3	16.0	GO:0042420	dopamine catabolic process(GO:0042420)
5.3	47.9	GO:0072331	signal transduction by p53 class mediator(GO:0072331)
5.3	53.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
5.3	5.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
5.3	126.9	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
5.3	42.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
5.3	21.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
5.3	21.1	GO:0045059	positive thymic T cell selection(GO:0045059)
5.3	10.5	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
5.3	21.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
5.3	10.5	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
5.2	47.1	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
5.2	5.2	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
5.2	5.2	GO:0043457	regulation of cellular respiration(GO:0043457)
5.2	203.3	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
5.2	15.6	GO:0006857	oligopeptide transport(GO:0006857)
5.2	10.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
5.2	62.2	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
5.2	114.1	GO:0000027	ribosomal large subunit assembly(GO:0000027)
5.2	31.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
5.2	10.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
5.2	20.7	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
5.2	15.5	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
5.2	46.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
5.2	30.9	GO:0033044	regulation of chromosome organization(GO:0033044)
5.2	77.3	GO:0006829	zinc II ion transport(GO:0006829)
5.2	25.8	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566)
5.1	56.5	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
5.1	5.1	GO:0006476	protein deacetylation(GO:0006476)
5.1	30.8	GO:0046889	positive regulation of lipid biosynthetic process(GO:0046889)
5.1	35.9	GO:0000028	ribosomal small subunit assembly(GO:0000028)
5.1	92.3	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
5.1	25.6	GO:0071985	multivesicular body sorting pathway(GO:0071985)
5.1	10.2	GO:0010884	positive regulation of lipid storage(GO:0010884)
5.1	81.7	GO:0070527	platelet aggregation(GO:0070527)
5.1	5.1	GO:0009650	UV protection(GO:0009650)
5.1	15.3	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
5.1	101.7	GO:1901998	toxin transport(GO:1901998)
5.1	71.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
5.1	5.1	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
5.0	25.2	GO:0000154	rRNA modification(GO:0000154)
5.0	115.4	GO:0045454	cell redox homeostasis(GO:0045454)
5.0	20.0	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
5.0	35.0	GO:1902017	regulation of cilium assembly(GO:1902017)
5.0	29.9	GO:0010507	negative regulation of autophagy(GO:0010507)
5.0	20.0	GO:0071514	genetic imprinting(GO:0071514)
5.0	10.0	GO:0046519	sphingoid metabolic process(GO:0046519)
5.0	34.9	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
5.0	164.2	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
5.0	14.9	GO:0031468	nuclear envelope reassembly(GO:0031468)
4.9	14.8	GO:0016559	peroxisome fission(GO:0016559)
4.9	14.8	GO:0010669	epithelial structure maintenance(GO:0010669)
4.9	44.3	GO:0002385	mucosal immune response(GO:0002385)
4.9	29.4	GO:0030500	regulation of bone mineralization(GO:0030500)
4.9	78.2	GO:0003009	skeletal muscle contraction(GO:0003009)
4.9	4.9	GO:0030811	regulation of nucleotide catabolic process(GO:0030811)
4.9	9.7	GO:0035562	negative regulation of chromatin binding(GO:0035562)
4.9	4.9	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
4.8	14.5	GO:0043628	ncRNA 3'-end processing(GO:0043628)
4.8	14.5	GO:0035510	DNA dealkylation(GO:0035510)
4.8	19.4	GO:0001841	neural tube formation(GO:0001841)
4.8	9.7	GO:0031018	endocrine pancreas development(GO:0031018)
4.8	4.8	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
4.8	4.8	GO:0003351	epithelial cilium movement(GO:0003351)
4.8	24.0	GO:0000723	telomere maintenance(GO:0000723) telomere organization(GO:0032200)
4.8	9.6	GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510) positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
4.8	4.8	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
4.8	52.5	GO:0009267	cellular response to starvation(GO:0009267)
4.8	4.8	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
4.8	9.5	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
4.8	4.8	GO:0048625	myoblast fate commitment(GO:0048625)
4.7	71.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
4.7	23.7	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
4.7	9.5	GO:0006776	vitamin A metabolic process(GO:0006776)
4.7	4.7	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
4.7	32.9	GO:0042574	retinal metabolic process(GO:0042574)
4.7	9.4	GO:0071359	cellular response to dsRNA(GO:0071359)
4.7	51.7	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
4.7	4.7	GO:0045061	negative thymic T cell selection(GO:0045060) thymic T cell selection(GO:0045061)
4.7	4.7	GO:0044539	long-chain fatty acid import(GO:0044539)
4.7	9.4	GO:0030852	regulation of granulocyte differentiation(GO:0030852)
4.7	9.3	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
4.7	32.7	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
4.7	65.3	GO:0006284	base-excision repair(GO:0006284)
4.7	9.3	GO:0035511	oxidative DNA demethylation(GO:0035511)
4.6	83.6	GO:0006040	amino sugar metabolic process(GO:0006040)
4.6	27.8	GO:0061515	myeloid cell development(GO:0061515)
4.6	18.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
4.6	41.7	GO:0061436	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
4.6	13.9	GO:0051639	actin filament network formation(GO:0051639)
4.6	23.0	GO:0051013	microtubule severing(GO:0051013)
4.6	4.6	GO:0019083	viral transcription(GO:0019083)
4.6	23.0	GO:0046605	regulation of centrosome cycle(GO:0046605)
4.6	4.6	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
4.6	9.2	GO:0048246	macrophage chemotaxis(GO:0048246)
4.6	133.0	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
4.6	32.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
4.6	132.5	GO:0007059	chromosome segregation(GO:0007059)
4.6	13.7	GO:0045404	positive regulation of interleukin-4 biosynthetic process(GO:0045404)
4.5	4.5	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
4.5	4.5	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
4.5	49.7	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
4.5	27.1	GO:0030168	platelet activation(GO:0030168)
4.5	13.5	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
4.5	9.0	GO:1903543	regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
4.5	4.5	GO:0007060	male meiosis chromosome segregation(GO:0007060)
4.5	13.5	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
4.5	17.9	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
4.5	9.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
4.5	4.5	GO:0051464	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
4.5	17.9	GO:0006026	aminoglycan catabolic process(GO:0006026)
4.5	8.9	GO:2000401	regulation of lymphocyte migration(GO:2000401)
4.5	4.5	GO:0021570	rhombomere 4 development(GO:0021570)
4.4	53.3	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
4.4	101.9	GO:0006635	fatty acid beta-oxidation(GO:0006635)
4.4	13.3	GO:0050832	defense response to fungus(GO:0050832)
4.4	57.6	GO:0006446	regulation of translational initiation(GO:0006446)
4.4	35.4	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
4.4	17.7	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
4.4	57.2	GO:0051591	response to cAMP(GO:0051591)
4.4	26.4	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
4.4	4.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
4.4	8.8	GO:0015846	polyamine transport(GO:0015846)
4.4	4.4	GO:0001951	intestinal D-glucose absorption(GO:0001951)
4.4	4.4	GO:0070266	necroptotic process(GO:0070266)
4.3	52.2	GO:0048286	lung alveolus development(GO:0048286)
4.3	17.2	GO:0030261	chromosome condensation(GO:0030261)
4.3	17.2	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
4.3	17.2	GO:0006702	androgen biosynthetic process(GO:0006702)
4.3	90.1	GO:0042073	intraciliary transport(GO:0042073)
4.3	4.3	GO:0045651	positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
4.3	128.6	GO:0051321	meiotic cell cycle(GO:0051321)
4.3	4.3	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683)
4.3	4.3	GO:0032800	receptor biosynthetic process(GO:0032800)
4.3	8.5	GO:0006768	biotin metabolic process(GO:0006768)
4.2	4.2	GO:0032494	response to peptidoglycan(GO:0032494)
4.2	8.5	GO:0007088	regulation of mitotic nuclear division(GO:0007088)
4.2	21.2	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
4.2	16.9	GO:0030490	maturation of SSU-rRNA(GO:0030490)
4.2	71.6	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
4.2	12.6	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
4.2	155.4	GO:0016071	mRNA metabolic process(GO:0016071)
4.2	4.2	GO:0035112	genitalia morphogenesis(GO:0035112)
4.2	54.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
4.2	33.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
4.2	25.0	GO:0030593	neutrophil chemotaxis(GO:0030593)
4.2	12.5	GO:0006261	DNA-dependent DNA replication(GO:0006261)
4.2	29.1	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
4.2	16.6	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
4.1	28.9	GO:1901663	quinone biosynthetic process(GO:1901663)
4.1	16.5	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
4.1	4.1	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
4.1	8.2	GO:0045739	positive regulation of DNA repair(GO:0045739)
4.1	4.1	GO:2000779	regulation of double-strand break repair(GO:2000779)
4.1	8.2	GO:0035330	regulation of hippo signaling(GO:0035330)
4.1	12.3	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
4.1	8.2	GO:0002215	defense response to nematode(GO:0002215)
4.1	114.3	GO:0006909	phagocytosis(GO:0006909)
4.1	4.1	GO:0031049	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
4.1	56.9	GO:0035458	cellular response to interferon-beta(GO:0035458)
4.1	20.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
4.1	16.2	GO:0002825	regulation of T-helper 1 type immune response(GO:0002825)
4.1	12.2	GO:0060037	pharyngeal system development(GO:0060037)
4.0	24.3	GO:0035608	protein deglutamylation(GO:0035608)
4.0	64.7	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
4.0	8.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
4.0	12.0	GO:0045577	regulation of B cell differentiation(GO:0045577)
4.0	8.0	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
4.0	16.0	GO:0042756	drinking behavior(GO:0042756)
4.0	55.8	GO:0035904	aorta development(GO:0035904)
4.0	19.9	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
4.0	27.9	GO:0042832	defense response to protozoan(GO:0042832)
3.9	15.8	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
3.9	31.5	GO:0070193	synaptonemal complex organization(GO:0070193)
3.9	3.9	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
3.9	3.9	GO:0051985	negative regulation of chromosome segregation(GO:0051985)
3.9	11.7	GO:0006563	L-serine metabolic process(GO:0006563) L-serine biosynthetic process(GO:0006564)
3.9	27.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
3.9	11.7	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230)
3.9	11.7	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
3.9	70.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
3.9	7.8	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
3.9	314.7	GO:0032259	methylation(GO:0032259)
3.9	3.9	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
3.9	3.9	GO:0002281	macrophage activation involved in immune response(GO:0002281)
3.9	7.8	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
3.9	15.5	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
3.9	7.7	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
3.9	65.5	GO:0007030	Golgi organization(GO:0007030)
3.8	7.7	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
3.8	3.8	GO:0046033	AMP metabolic process(GO:0046033)
3.8	3.8	GO:0061437	renal system vasculature development(GO:0061437) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012)
3.8	19.1	GO:0007140	male meiosis(GO:0007140)
3.8	11.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.8	79.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
3.8	83.7	GO:0007265	Ras protein signal transduction(GO:0007265)
3.8	34.0	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
3.8	3.8	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
3.8	7.5	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
3.8	519.4	GO:0016567	protein ubiquitination(GO:0016567)
3.8	3.8	GO:0051657	maintenance of organelle location(GO:0051657)
3.8	94.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
3.8	18.8	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
3.7	22.5	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
3.7	7.5	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
3.7	3.7	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
3.7	123.1	GO:0032543	mitochondrial translation(GO:0032543)
3.7	3.7	GO:0070163	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.7	18.6	GO:0009303	rRNA transcription(GO:0009303)
3.7	7.4	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
3.7	77.6	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
3.7	3.7	GO:0035622	intrahepatic bile duct development(GO:0035622)
3.7	11.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
3.7	7.4	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
3.7	7.4	GO:0035455	response to interferon-alpha(GO:0035455)
3.7	7.3	GO:0060467	negative regulation of fertilization(GO:0060467)
3.7	7.3	GO:0061512	protein localization to cilium(GO:0061512)
3.7	18.3	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)
3.7	3.7	GO:0051023	regulation of immunoglobulin secretion(GO:0051023)
3.7	3.7	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
3.7	11.0	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
3.7	127.8	GO:0006457	protein folding(GO:0006457)
3.6	40.1	GO:0042246	tissue regeneration(GO:0042246)
3.6	47.4	GO:0050729	positive regulation of inflammatory response(GO:0050729)
3.6	39.7	GO:0007368	determination of left/right symmetry(GO:0007368)
3.6	3.6	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
3.6	32.2	GO:0006879	cellular iron ion homeostasis(GO:0006879)
3.6	10.7	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
3.6	68.0	GO:0060324	face development(GO:0060324)
3.6	14.3	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
3.5	113.5	GO:0043330	response to exogenous dsRNA(GO:0043330)
3.5	7.1	GO:0097066	response to thyroid hormone(GO:0097066)
3.5	269.4	GO:0006869	lipid transport(GO:0006869)
3.5	7.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
3.5	17.7	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
3.5	28.3	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
3.5	7.1	GO:0045911	positive regulation of DNA recombination(GO:0045911)
3.5	3.5	GO:0040009	regulation of growth rate(GO:0040009)
3.5	17.6	GO:0046677	response to antibiotic(GO:0046677)
3.5	3.5	GO:0048850	hypophysis morphogenesis(GO:0048850)
3.5	38.3	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
3.5	27.8	GO:0032680	regulation of tumor necrosis factor production(GO:0032680)
3.5	17.4	GO:0046085	adenosine metabolic process(GO:0046085)
3.5	3.5	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
3.5	938.5	GO:0045892	negative regulation of transcription, DNA-templated(GO:0045892)
3.5	41.5	GO:0043627	response to estrogen(GO:0043627)
3.5	17.3	GO:0042990	regulation of transcription factor import into nucleus(GO:0042990)
3.4	31.0	GO:0045047	protein targeting to ER(GO:0045047)
3.4	10.3	GO:0019321	pentose metabolic process(GO:0019321)
3.4	3.4	GO:0021847	ventricular zone neuroblast division(GO:0021847)
3.4	17.0	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
3.4	30.5	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
3.4	77.9	GO:0006626	protein targeting to mitochondrion(GO:0006626)
3.4	13.5	GO:0050704	regulation of interleukin-1 secretion(GO:0050704)
3.4	3.4	GO:0036297	interstrand cross-link repair(GO:0036297)
3.4	16.8	GO:0018200	protein polyglutamylation(GO:0018095) peptidyl-glutamic acid modification(GO:0018200)
3.4	77.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
3.4	3.4	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
3.4	13.4	GO:0001771	immunological synapse formation(GO:0001771)
3.4	16.8	GO:0032612	interleukin-1 production(GO:0032612)
3.3	3.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
3.3	6.6	GO:0044033	multi-organism metabolic process(GO:0044033)
3.3	3.3	GO:2000319	regulation of T-helper 17 cell differentiation(GO:2000319)
3.3	46.2	GO:0015701	bicarbonate transport(GO:0015701)
3.3	214.4	GO:0051301	cell division(GO:0051301)
3.3	23.0	GO:0010498	proteasomal protein catabolic process(GO:0010498)
3.3	9.8	GO:0014896	muscle hypertrophy(GO:0014896)
3.3	16.4	GO:0001890	placenta development(GO:0001890)
3.3	6.5	GO:2000354	regulation of ovarian follicle development(GO:2000354)
3.3	45.5	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
3.2	32.5	GO:0006270	DNA replication initiation(GO:0006270)
3.2	3.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
3.2	42.0	GO:0043087	regulation of GTPase activity(GO:0043087)
3.2	12.9	GO:0003323	type B pancreatic cell development(GO:0003323)
3.2	58.0	GO:0031424	keratinization(GO:0031424)
3.2	9.7	GO:0001659	temperature homeostasis(GO:0001659)
3.2	3.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
3.2	16.1	GO:0048736	appendage development(GO:0048736) limb development(GO:0060173)
3.2	3.2	GO:0048251	elastic fiber assembly(GO:0048251)
3.2	6.4	GO:0002183	cytoplasmic translational initiation(GO:0002183)
3.1	9.4	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
3.1	6.3	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
3.1	15.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
3.1	3.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
3.1	590.2	GO:0006412	translation(GO:0006412)
3.1	12.5	GO:0009235	cobalamin metabolic process(GO:0009235)
3.1	37.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
3.1	6.2	GO:0008209	androgen metabolic process(GO:0008209)
3.1	9.2	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
3.1	3.1	GO:0033684	regulation of luteinizing hormone secretion(GO:0033684)
3.0	12.2	GO:0060976	coronary vasculature development(GO:0060976)
3.0	121.3	GO:0006281	DNA repair(GO:0006281)
3.0	15.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
3.0	6.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
3.0	3.0	GO:0040016	embryonic cleavage(GO:0040016)
3.0	95.2	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
3.0	5.9	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
3.0	17.8	GO:0070207	protein homotrimerization(GO:0070207)
3.0	5.9	GO:0018126	protein hydroxylation(GO:0018126)
2.9	5.9	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
2.9	55.6	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
2.9	20.5	GO:0098773	skin epidermis development(GO:0098773)
2.9	2.9	GO:0014831	gastro-intestinal system smooth muscle contraction(GO:0014831)
2.9	5.8	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
2.9	8.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
2.9	14.4	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
2.9	17.2	GO:0000338	protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
2.9	5.7	GO:0033762	response to glucagon(GO:0033762)
2.8	8.5	GO:0043473	pigmentation(GO:0043473)
2.8	2.8	GO:0016125	sterol metabolic process(GO:0016125)
2.8	2.8	GO:0046640	regulation of alpha-beta T cell proliferation(GO:0046640)
2.8	2.8	GO:0040019	positive regulation of embryonic development(GO:0040019)
2.8	359.5	GO:0008380	RNA splicing(GO:0008380)
2.8	28.3	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
2.8	16.9	GO:0043550	regulation of lipid kinase activity(GO:0043550)
2.8	2.8	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
2.8	5.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
2.8	8.3	GO:0034440	fatty acid oxidation(GO:0019395) lipid oxidation(GO:0034440)
2.8	5.6	GO:0045777	positive regulation of blood pressure(GO:0045777)
2.8	2.8	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
2.8	19.3	GO:0006182	cGMP biosynthetic process(GO:0006182)
2.8	8.3	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
2.7	22.0	GO:0090280	positive regulation of calcium ion import(GO:0090280)
2.7	11.0	GO:0002347	response to tumor cell(GO:0002347)
2.7	8.2	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
2.7	2.7	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.7	8.2	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
2.7	2.7	GO:0048066	developmental pigmentation(GO:0048066)
2.7	8.0	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
2.7	10.6	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
2.7	87.8	GO:0043547	positive regulation of GTPase activity(GO:0043547)
2.7	10.6	GO:0090329	regulation of DNA-dependent DNA replication(GO:0090329)
2.6	41.8	GO:0006956	complement activation(GO:0006956)
2.6	10.3	GO:0007044	cell-substrate junction assembly(GO:0007044)
2.6	2.6	GO:0051683	establishment of Golgi localization(GO:0051683)
2.5	2.5	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
2.5	15.1	GO:0070166	enamel mineralization(GO:0070166)
2.5	2.5	GO:0046174	polyol catabolic process(GO:0046174)
2.5	2.5	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
2.5	34.7	GO:0019835	cytolysis(GO:0019835)
2.4	9.7	GO:0009615	response to virus(GO:0009615)
2.4	55.7	GO:0008033	tRNA processing(GO:0008033)
2.4	2.4	GO:0035270	endocrine system development(GO:0035270)
2.4	2.4	GO:1902473	regulation of protein localization to synapse(GO:1902473)
2.4	7.2	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
2.4	2.4	GO:0001974	blood vessel remodeling(GO:0001974)
2.4	2.4	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
2.4	23.5	GO:0050728	negative regulation of inflammatory response(GO:0050728)
2.3	21.0	GO:0071453	cellular response to oxygen levels(GO:0071453)
2.3	6.9	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
2.3	108.5	GO:0001701	in utero embryonic development(GO:0001701)
2.3	2.3	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
2.3	2.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
2.3	367.6	GO:0048232	male gamete generation(GO:0048232)
2.3	22.9	GO:0030322	stabilization of membrane potential(GO:0030322)
2.3	2.3	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
2.3	6.8	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.3	4.5	GO:0018394	peptidyl-lysine acetylation(GO:0018394)
2.3	9.0	GO:0071435	potassium ion export(GO:0071435)
2.2	4.4	GO:0097499	protein localization to nonmotile primary cilium(GO:0097499)
2.2	15.5	GO:0009954	proximal/distal pattern formation(GO:0009954)
2.2	6.6	GO:0034612	response to tumor necrosis factor(GO:0034612)
2.2	2.2	GO:0035898	parathyroid hormone secretion(GO:0035898)
2.2	2.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
2.2	24.0	GO:0006953	acute-phase response(GO:0006953)
2.2	6.5	GO:0009988	cell-cell recognition(GO:0009988)
2.2	2.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
2.2	2.2	GO:0090281	negative regulation of calcium ion import(GO:0090281)
2.1	2.1	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
2.1	2.1	GO:0035456	response to interferon-beta(GO:0035456)
2.1	49.3	GO:0046777	protein autophosphorylation(GO:0046777)
2.1	6.4	GO:0071466	xenobiotic metabolic process(GO:0006805) cellular response to xenobiotic stimulus(GO:0071466)
2.1	2.1	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370)
2.1	27.4	GO:0030641	regulation of cellular pH(GO:0030641)
2.1	6.3	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
2.1	4.2	GO:0030259	lipid glycosylation(GO:0030259)
2.1	4.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
2.1	6.3	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
2.1	12.6	GO:0045824	negative regulation of innate immune response(GO:0045824)
2.1	2.1	GO:0090189	regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
2.1	2.1	GO:0005984	disaccharide metabolic process(GO:0005984)
2.1	2.1	GO:0032275	luteinizing hormone secretion(GO:0032275)
2.1	6.2	GO:0097186	amelogenesis(GO:0097186)
2.1	2.1	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
2.1	8.2	GO:0006465	signal peptide processing(GO:0006465)
2.0	20.5	GO:0043406	positive regulation of MAP kinase activity(GO:0043406)
2.0	8.1	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
2.0	8.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
2.0	12.0	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
2.0	82.0	GO:0042384	cilium assembly(GO:0042384)
2.0	5.9	GO:0045851	pH reduction(GO:0045851)
2.0	3.9	GO:0030888	regulation of B cell proliferation(GO:0030888)
2.0	3.9	GO:0006401	RNA catabolic process(GO:0006401)
1.9	11.6	GO:0050853	B cell receptor signaling pathway(GO:0050853)
1.9	5.8	GO:2001198	regulation of dendritic cell differentiation(GO:2001198)
1.9	1.9	GO:0015791	polyol transport(GO:0015791)
1.9	3.8	GO:0034505	tooth mineralization(GO:0034505)
1.9	7.6	GO:0045069	regulation of viral genome replication(GO:0045069)
1.9	22.7	GO:0006006	glucose metabolic process(GO:0006006)
1.9	13.2	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
1.9	20.6	GO:0071560	cellular response to transforming growth factor beta stimulus(GO:0071560)
1.9	1.9	GO:0043276	anoikis(GO:0043276)
1.9	1.9	GO:0006106	fumarate metabolic process(GO:0006106)
1.8	66.2	GO:0070482	response to oxygen levels(GO:0070482)
1.8	7.3	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090100)
1.8	3.7	GO:0002507	tolerance induction(GO:0002507)
1.8	3.6	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
1.8	1.8	GO:2000047	regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
1.8	96.6	GO:0051607	defense response to virus(GO:0051607)
1.8	5.4	GO:0042255	ribosome assembly(GO:0042255)
1.8	122.8	GO:0051346	negative regulation of hydrolase activity(GO:0051346)
1.8	63.8	GO:0042060	wound healing(GO:0042060)
1.8	1.8	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
1.8	72.1	GO:0071222	cellular response to lipopolysaccharide(GO:0071222)
1.7	1.7	GO:0036093	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
1.7	1.7	GO:0006826	iron ion transport(GO:0006826)
1.7	6.8	GO:0006590	thyroid hormone generation(GO:0006590)
1.7	1.7	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
1.7	110.7	GO:0006631	fatty acid metabolic process(GO:0006631)
1.7	1.7	GO:0015931	nucleobase-containing compound transport(GO:0015931)
1.7	13.3	GO:0052697	xenobiotic glucuronidation(GO:0052697)
1.7	1.7	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659)
1.6	1.6	GO:1990542	mitochondrial transmembrane transport(GO:1990542)
1.6	1.6	GO:0000060	protein import into nucleus, translocation(GO:0000060)
1.6	1.6	GO:0060512	prostate gland morphogenesis(GO:0060512)
1.6	11.4	GO:0044782	cilium organization(GO:0044782)
1.6	3.3	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
1.6	144.1	GO:0030163	protein catabolic process(GO:0030163)
1.6	4.8	GO:0070995	NADPH oxidation(GO:0070995)
1.6	3.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
1.6	1.6	GO:0006650	glycerophospholipid metabolic process(GO:0006650)
1.5	1.5	GO:0009624	response to nematode(GO:0009624)
1.5	3.1	GO:0030225	macrophage differentiation(GO:0030225)
1.5	3.1	GO:0048733	sebaceous gland development(GO:0048733)
1.5	1.5	GO:0014866	skeletal myofibril assembly(GO:0014866)
1.5	13.5	GO:0008089	anterograde axonal transport(GO:0008089)
1.5	16.5	GO:0022900	electron transport chain(GO:0022900)
1.5	7.5	GO:0014829	vascular smooth muscle contraction(GO:0014829)
1.5	1.5	GO:1901264	carbohydrate derivative transport(GO:1901264)
1.5	3.0	GO:0044704	single-organism reproductive behavior(GO:0044704)
1.5	4.5	GO:0036158	outer dynein arm assembly(GO:0036158)
1.5	3.0	GO:0048485	sympathetic nervous system development(GO:0048485)
1.5	1.5	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
1.5	11.8	GO:0072348	sulfur compound transport(GO:0072348)
1.4	2.9	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.4	10.0	GO:0009060	aerobic respiration(GO:0009060)
1.4	2.9	GO:0032094	response to food(GO:0032094)
1.4	1017.5	GO:0006351	transcription, DNA-templated(GO:0006351)
1.4	1.4	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
1.4	4.1	GO:0070231	T cell apoptotic process(GO:0070231)
1.4	8.2	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
1.4	1.4	GO:0040029	regulation of gene expression, epigenetic(GO:0040029)
1.4	16.2	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
1.3	6.7	GO:0061756	leukocyte adhesion to vascular endothelial cell(GO:0061756)
1.3	2.7	GO:0001782	B cell homeostasis(GO:0001782)
1.3	10.6	GO:0022613	ribonucleoprotein complex biogenesis(GO:0022613)
1.3	2.6	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
1.3	2.6	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
1.3	3.9	GO:0032836	glomerular basement membrane development(GO:0032836)
1.3	14.3	GO:0007602	phototransduction(GO:0007602)
1.3	3.9	GO:1904659	glucose transmembrane transport(GO:1904659)
1.3	2.6	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
1.2	2.5	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
1.2	1.2	GO:0045639	positive regulation of myeloid cell differentiation(GO:0045639)
1.2	3.6	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
1.2	1.2	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
1.2	1.2	GO:0002551	mast cell chemotaxis(GO:0002551)
1.2	1.2	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
1.2	3.5	GO:0002026	regulation of the force of heart contraction(GO:0002026)
1.1	3.4	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
1.1	4.5	GO:0009225	nucleotide-sugar metabolic process(GO:0009225)
1.1	12.3	GO:0032496	response to lipopolysaccharide(GO:0032496)
1.1	2.2	GO:0006739	NADP metabolic process(GO:0006739)
1.1	1.1	GO:0015747	urate transport(GO:0015747)
1.1	6.3	GO:0051205	protein insertion into membrane(GO:0051205)
1.0	2.1	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
1.0	3.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
1.0	7.2	GO:0015693	magnesium ion transport(GO:0015693)
1.0	1.0	GO:0043589	skin morphogenesis(GO:0043589)
1.0	1.0	GO:0051132	NK T cell activation(GO:0051132)
1.0	10.6	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
1.0	1.0	GO:0009394	2'-deoxyribonucleotide metabolic process(GO:0009394) deoxyribose phosphate metabolic process(GO:0019692)
1.0	1.0	GO:0042107	cytokine metabolic process(GO:0042107)
1.0	1.0	GO:0060022	hard palate development(GO:0060022)
0.9	2.8	GO:0072091	regulation of stem cell proliferation(GO:0072091)
0.9	4.7	GO:0070664	negative regulation of leukocyte proliferation(GO:0070664)
0.9	31.0	GO:0016042	lipid catabolic process(GO:0016042)
0.9	0.9	GO:0033280	response to vitamin D(GO:0033280)
0.9	2.7	GO:0043043	peptide biosynthetic process(GO:0043043)
0.9	2.7	GO:0006986	response to unfolded protein(GO:0006986)
0.9	17.8	GO:0007160	cell-matrix adhesion(GO:0007160)
0.9	52.2	GO:0098542	defense response to other organism(GO:0098542)
0.9	0.9	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.9	0.9	GO:0043455	regulation of secondary metabolic process(GO:0043455)
0.8	31.4	GO:0019882	antigen processing and presentation(GO:0019882)
0.8	3.4	GO:0080154	regulation of fertilization(GO:0080154)
0.8	0.8	GO:0052803	histamine metabolic process(GO:0001692) imidazole-containing compound metabolic process(GO:0052803)
0.8	2.5	GO:0034453	microtubule anchoring(GO:0034453)
0.8	1.7	GO:0019695	choline metabolic process(GO:0019695)
0.8	0.8	GO:0097193	intrinsic apoptotic signaling pathway(GO:0097193)
0.8	0.8	GO:0006624	vacuolar protein processing(GO:0006624)
0.8	0.8	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.8	3.9	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.8	0.8	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.8	0.8	GO:0031033	myosin filament organization(GO:0031033)
0.7	16.4	GO:0008643	carbohydrate transport(GO:0008643)
0.7	0.7	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.7	10.8	GO:0045444	fat cell differentiation(GO:0045444)
0.7	2.9	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.7	0.7	GO:0001562	response to protozoan(GO:0001562)
0.7	173.7	GO:0006508	proteolysis(GO:0006508)
0.7	7.0	GO:0042113	B cell activation(GO:0042113)
0.7	6.2	GO:0017038	protein import(GO:0017038)
0.7	0.7	GO:0071559	response to transforming growth factor beta(GO:0071559)
0.7	0.7	GO:0010259	multicellular organism aging(GO:0010259)
0.7	0.7	GO:0002819	regulation of adaptive immune response(GO:0002819)
0.7	0.7	GO:0033003	regulation of mast cell activation(GO:0033003)
0.7	2.0	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.6	0.6	GO:0046148	pigment biosynthetic process(GO:0046148)
0.6	3.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.6	0.6	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.6	0.6	GO:0002285	lymphocyte activation involved in immune response(GO:0002285)
0.6	0.6	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.6	3.0	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.6	0.6	GO:0071763	nuclear membrane organization(GO:0071763)
0.6	1.2	GO:0051546	keratinocyte migration(GO:0051546)
0.6	17.9	GO:0006396	RNA processing(GO:0006396)
0.6	0.6	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.5	0.5	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.5	0.5	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5	2.1	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.5	98.8	GO:0055114	oxidation-reduction process(GO:0055114)
0.5	0.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5	18.4	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.5	3.0	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.5	0.9	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.5	3.2	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.5	0.5	GO:0007369	gastrulation(GO:0007369)
0.4	2.2	GO:0003341	cilium movement(GO:0003341)
0.4	0.4	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.4	0.9	GO:0006265	DNA topological change(GO:0006265)
0.4	0.4	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.4	0.4	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.4	0.4	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.4	1.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.4	0.4	GO:0009620	response to fungus(GO:0009620)
0.4	0.8	GO:0099515	actin filament-based transport(GO:0099515)
0.4	0.4	GO:0006020	inositol metabolic process(GO:0006020)
0.4	0.7	GO:0086043	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.4	1.4	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.4	12.4	GO:0050909	sensory perception of taste(GO:0050909)
0.3	0.3	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154)
0.3	0.6	GO:0071496	cellular response to external stimulus(GO:0071496)
0.3	0.3	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.3	0.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3	0.3	GO:0034341	response to interferon-gamma(GO:0034341)
0.3	0.6	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.3	1.7	GO:0030101	natural killer cell activation(GO:0030101)
0.3	0.3	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.3	0.5	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.2	3.7	GO:0010629	negative regulation of gene expression(GO:0010629)
0.2	0.5	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2	0.2	GO:0033032	regulation of myeloid cell apoptotic process(GO:0033032)
0.2	0.2	GO:0015874	norepinephrine transport(GO:0015874)
0.1	0.1	GO:0032528	microvillus organization(GO:0032528)
0.1	32.2	GO:0050907	detection of chemical stimulus involved in sensory perception(GO:0050907)
0.1	1.5	GO:0019439	aromatic compound catabolic process(GO:0019439)
0.1	0.4	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.1	11.4	GO:0019236	response to pheromone(GO:0019236)
0.1	0.1	GO:0036336	dendritic cell migration(GO:0036336)
0.1	0.1	GO:0009445	putrescine metabolic process(GO:0009445)
0.1	0.3	GO:0055006	cardiac cell development(GO:0055006)
0.1	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0060179	male mating behavior(GO:0060179)
0.0	0.4	GO:0051253	negative regulation of RNA metabolic process(GO:0051253)
0.0	0.3	GO:1901657	glycosyl compound metabolic process(GO:1901657)
0.0	0.0	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
54.2	162.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
46.2	277.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
45.2	180.9	GO:0072487	MSL complex(GO:0072487)
41.0	205.2	GO:0016461	unconventional myosin complex(GO:0016461)
39.4	197.0	GO:0033093	Weibel-Palade body(GO:0033093)
37.8	151.1	GO:0035189	Rb-E2F complex(GO:0035189)
37.5	187.5	GO:0005638	lamin filament(GO:0005638)
36.3	254.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
34.5	103.6	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
33.9	135.7	GO:0035363	histone locus body(GO:0035363)
33.5	100.5	GO:1990597	AIP1-IRE1 complex(GO:1990597)
32.3	129.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
30.9	92.7	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
30.4	121.5	GO:0031094	platelet dense tubular network(GO:0031094)
30.2	120.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
29.7	178.3	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
28.5	85.6	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
28.1	140.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
28.1	112.4	GO:0071141	SMAD protein complex(GO:0071141)
27.9	83.7	GO:0031523	Myb complex(GO:0031523)
27.2	54.4	GO:0036488	CHOP-C/EBP complex(GO:0036488)
26.8	107.3	GO:1990204	oxidoreductase complex(GO:1990204)
26.7	80.1	GO:0043293	apoptosome(GO:0043293)
26.7	213.4	GO:0030056	hemidesmosome(GO:0030056)
26.3	105.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
26.0	26.0	GO:0005914	spot adherens junction(GO:0005914)
25.5	101.8	GO:0042825	TAP complex(GO:0042825)
25.4	101.8	GO:0005642	annulate lamellae(GO:0005642)
25.3	1520.4	GO:0000118	histone deacetylase complex(GO:0000118)
25.0	174.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
24.3	24.3	GO:0031933	telomeric heterochromatin(GO:0031933)
24.3	97.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
24.0	144.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
23.9	358.1	GO:0000421	autophagosome membrane(GO:0000421)
23.8	71.4	GO:0097451	glial limiting end-foot(GO:0097451)
23.6	212.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
23.4	210.2	GO:0002116	semaphorin receptor complex(GO:0002116)
23.2	92.8	GO:0097524	sperm plasma membrane(GO:0097524)
23.0	207.3	GO:0031010	ISWI-type complex(GO:0031010)
23.0	160.7	GO:0070688	MLL5-L complex(GO:0070688)
22.9	228.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
22.5	67.5	GO:0032127	dense core granule membrane(GO:0032127)
22.4	156.7	GO:0005677	chromatin silencing complex(GO:0005677)
22.3	111.7	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
22.3	111.3	GO:0097470	ribbon synapse(GO:0097470)
22.0	22.0	GO:0036449	microtubule minus-end(GO:0036449)
21.8	240.3	GO:0035102	PRC1 complex(GO:0035102)
21.8	174.6	GO:0001650	fibrillar center(GO:0001650)
21.8	283.6	GO:0031528	microvillus membrane(GO:0031528)
21.7	281.9	GO:0016514	SWI/SNF complex(GO:0016514)
21.7	21.7	GO:0097512	cardiac myofibril(GO:0097512)
21.4	214.2	GO:0070938	contractile ring(GO:0070938)
21.1	63.2	GO:0097443	sorting endosome(GO:0097443)
20.3	60.9	GO:0097413	Lewy body(GO:0097413)
20.1	180.5	GO:0090544	BAF-type complex(GO:0090544)
20.0	59.9	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
19.9	159.4	GO:0001939	female pronucleus(GO:0001939)
19.9	79.4	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
19.7	137.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
19.7	59.0	GO:0043259	laminin-10 complex(GO:0043259)
19.4	58.1	GO:0000811	GINS complex(GO:0000811)
19.4	58.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
19.3	154.6	GO:0016600	flotillin complex(GO:0016600)
19.3	38.6	GO:0000322	storage vacuole(GO:0000322)
19.2	57.5	GO:0000235	astral microtubule(GO:0000235)
19.1	57.3	GO:0005745	m-AAA complex(GO:0005745)
18.9	283.5	GO:0031519	PcG protein complex(GO:0031519)
18.5	74.1	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
18.4	91.8	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
18.1	54.3	GO:1990357	terminal web(GO:1990357)
18.0	18.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
17.5	175.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
17.5	70.1	GO:0030689	Noc complex(GO:0030689)
17.4	17.4	GO:0016939	kinesin II complex(GO:0016939)
17.4	34.7	GO:0097418	neurofibrillary tangle(GO:0097418)
17.3	500.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
17.2	258.4	GO:0030014	CCR4-NOT complex(GO:0030014)
17.2	51.5	GO:0099738	cell cortex region(GO:0099738)
17.1	51.4	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
17.1	85.3	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
17.0	118.9	GO:0000788	nuclear nucleosome(GO:0000788)
16.9	84.7	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
16.9	16.9	GO:1990423	RZZ complex(GO:1990423)
16.7	16.7	GO:0032587	ruffle membrane(GO:0032587)
16.7	66.6	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
16.6	49.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
16.6	16.6	GO:0044292	dendrite terminus(GO:0044292)
16.4	131.4	GO:0032593	insulin-responsive compartment(GO:0032593)
16.4	16.4	GO:0005818	aster(GO:0005818)
16.4	114.5	GO:0042382	paraspeckles(GO:0042382)
16.4	32.7	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
16.3	130.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
16.3	65.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
16.2	48.6	GO:0016602	CCAAT-binding factor complex(GO:0016602)
16.2	80.9	GO:1990023	mitotic spindle midzone(GO:1990023)
16.1	64.5	GO:0071203	WASH complex(GO:0071203)
16.0	64.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
16.0	48.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
16.0	159.6	GO:0097539	ciliary transition fiber(GO:0097539)
15.9	111.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
15.9	669.0	GO:0017053	transcriptional repressor complex(GO:0017053)
15.9	47.7	GO:0031084	BLOC-2 complex(GO:0031084)
15.9	47.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
15.8	47.5	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
15.7	94.3	GO:0090543	Flemming body(GO:0090543)
15.7	125.7	GO:0042641	actomyosin(GO:0042641)
15.7	251.0	GO:0002102	podosome(GO:0002102)
15.7	814.8	GO:0032432	actin filament bundle(GO:0032432)
15.7	31.3	GO:0030125	clathrin vesicle coat(GO:0030125)
15.6	46.8	GO:0005955	calcineurin complex(GO:0005955)
15.6	62.3	GO:0044530	supraspliceosomal complex(GO:0044530)
15.6	46.7	GO:0097452	GAIT complex(GO:0097452)
15.4	46.3	GO:0035061	interchromatin granule(GO:0035061)
15.4	15.4	GO:0030136	clathrin-coated vesicle(GO:0030136)
15.3	122.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
15.3	198.5	GO:0030914	STAGA complex(GO:0030914)
15.2	45.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
15.1	438.8	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
15.0	45.0	GO:0005828	kinetochore microtubule(GO:0005828)
15.0	119.8	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
14.8	59.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
14.7	191.1	GO:0038201	TOR complex(GO:0038201)
14.7	58.7	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
14.6	204.9	GO:0000786	nucleosome(GO:0000786)
14.6	43.7	GO:0005915	zonula adherens(GO:0005915)
14.5	145.0	GO:0097431	mitotic spindle pole(GO:0097431)
14.4	72.2	GO:0070820	tertiary granule(GO:0070820)
14.3	43.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
14.3	14.3	GO:0000439	core TFIIH complex(GO:0000439)
14.3	114.1	GO:0070578	RISC-loading complex(GO:0070578)
14.2	156.3	GO:0032039	integrator complex(GO:0032039)
14.2	170.2	GO:0097440	apical dendrite(GO:0097440)
14.2	14.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
14.2	42.5	GO:0031417	NatC complex(GO:0031417)
14.1	28.3	GO:0005879	axonemal microtubule(GO:0005879)
14.1	84.6	GO:0031415	NatA complex(GO:0031415)
14.0	70.1	GO:0005916	fascia adherens(GO:0005916)
14.0	280.0	GO:0035145	exon-exon junction complex(GO:0035145)
14.0	14.0	GO:0030175	filopodium(GO:0030175)
14.0	14.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
13.9	41.6	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
13.7	54.6	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
13.5	661.3	GO:0000123	histone acetyltransferase complex(GO:0000123)
13.4	793.4	GO:0016363	nuclear matrix(GO:0016363)
13.4	53.8	GO:0031988	membrane-bounded vesicle(GO:0031988)
13.4	26.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
13.4	134.2	GO:0005721	pericentric heterochromatin(GO:0005721)
13.3	26.7	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
13.2	185.2	GO:0005719	nuclear euchromatin(GO:0005719)
13.2	52.7	GO:0015629	actin cytoskeleton(GO:0015629)
13.1	39.4	GO:0097149	centralspindlin complex(GO:0097149)
13.1	39.3	GO:1990462	omegasome(GO:1990462)
13.1	248.6	GO:0071010	prespliceosome(GO:0071010)
13.1	91.4	GO:0034709	methylosome(GO:0034709)
13.1	26.1	GO:0098536	deuterosome(GO:0098536)
13.0	26.1	GO:1990923	PET complex(GO:1990923)
13.0	13.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
12.9	129.3	GO:0010369	chromocenter(GO:0010369)
12.9	51.6	GO:0005672	transcription factor TFIIA complex(GO:0005672)
12.9	38.6	GO:0071817	MMXD complex(GO:0071817)
12.8	320.6	GO:0008023	transcription elongation factor complex(GO:0008023)
12.8	25.5	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
12.8	114.8	GO:0031143	pseudopodium(GO:0031143)
12.7	38.2	GO:0032133	chromosome passenger complex(GO:0032133)
12.7	38.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
12.7	89.0	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
12.7	266.7	GO:0005680	anaphase-promoting complex(GO:0005680)
12.7	63.4	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
12.7	658.7	GO:0030863	cortical cytoskeleton(GO:0030863)
12.7	215.1	GO:0000242	pericentriolar material(GO:0000242)
12.6	50.5	GO:0044194	cytolytic granule(GO:0044194)
12.6	25.3	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
12.6	201.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
12.5	87.6	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
12.5	87.3	GO:0033061	DNA recombinase mediator complex(GO:0033061)
12.4	74.4	GO:0008385	IkappaB kinase complex(GO:0008385)
12.4	99.1	GO:0045120	pronucleus(GO:0045120)
12.4	37.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
12.4	74.2	GO:0042587	glycogen granule(GO:0042587)
12.3	24.7	GO:0042405	nuclear inclusion body(GO:0042405)
12.3	73.7	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
12.2	73.3	GO:0097542	ciliary tip(GO:0097542)
12.2	3214.6	GO:0005925	focal adhesion(GO:0005925)
12.1	301.9	GO:0016592	mediator complex(GO:0016592)
12.1	555.2	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
12.1	84.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
12.0	636.5	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
11.9	178.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
11.9	71.2	GO:0044666	MLL3/4 complex(GO:0044666)
11.9	213.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
11.8	82.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
11.8	35.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
11.7	11.7	GO:0000346	transcription export complex(GO:0000346)
11.7	11.7	GO:0030896	checkpoint clamp complex(GO:0030896)
11.6	23.3	GO:0048476	Holliday junction resolvase complex(GO:0048476)
11.6	58.2	GO:0035861	site of double-strand break(GO:0035861)
11.6	174.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
11.6	23.2	GO:0005770	late endosome(GO:0005770)
11.5	11.5	GO:0044327	dendritic spine head(GO:0044327)
11.5	34.6	GO:0005588	collagen type V trimer(GO:0005588)
11.5	68.9	GO:0031080	nuclear pore outer ring(GO:0031080)
11.5	91.8	GO:0005640	nuclear outer membrane(GO:0005640)
11.4	11.4	GO:0042585	germinal vesicle(GO:0042585)
11.4	79.7	GO:0044232	organelle membrane contact site(GO:0044232)
11.4	113.8	GO:0035631	CD40 receptor complex(GO:0035631)
11.3	79.4	GO:1990909	Wnt signalosome(GO:1990909)
11.3	45.3	GO:0033269	internode region of axon(GO:0033269)
11.3	565.5	GO:0005811	lipid particle(GO:0005811)
11.3	45.1	GO:0044294	dendritic growth cone(GO:0044294)
11.3	112.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
11.3	67.6	GO:0031512	motile primary cilium(GO:0031512)
11.2	67.5	GO:0005682	U5 snRNP(GO:0005682)
11.2	22.5	GO:0005610	laminin-5 complex(GO:0005610)
11.2	22.4	GO:0097342	ripoptosome(GO:0097342)
11.2	44.7	GO:0044815	DNA packaging complex(GO:0044815)
11.2	33.5	GO:1990130	Iml1 complex(GO:1990130)
11.1	77.6	GO:0070652	HAUS complex(GO:0070652)
11.1	66.4	GO:0031209	SCAR complex(GO:0031209)
11.0	132.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
11.0	241.1	GO:0012505	endomembrane system(GO:0012505)
10.9	54.6	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
10.9	87.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
10.8	325.0	GO:0005776	autophagosome(GO:0005776)
10.8	64.9	GO:0005796	Golgi lumen(GO:0005796)
10.8	32.4	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
10.8	97.0	GO:0070852	cell body fiber(GO:0070852)
10.8	107.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
10.7	32.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
10.7	53.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
10.6	202.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
10.6	127.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
10.5	42.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
10.4	188.0	GO:0042588	zymogen granule(GO:0042588)
10.4	114.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
10.4	104.3	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
10.4	31.1	GO:0072687	meiotic spindle(GO:0072687)
10.4	498.1	GO:0016605	PML body(GO:0016605)
10.4	20.7	GO:0005871	kinesin complex(GO:0005871)
10.4	1180.6	GO:0000790	nuclear chromatin(GO:0000790)
10.3	10.3	GO:0030891	VCB complex(GO:0030891)
10.3	247.0	GO:0005876	spindle microtubule(GO:0005876)
10.3	30.9	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
10.3	30.8	GO:0030915	Smc5-Smc6 complex(GO:0030915)
10.2	71.5	GO:0097208	alveolar lamellar body(GO:0097208)
10.2	40.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
10.2	71.3	GO:0035859	Seh1-associated complex(GO:0035859)
10.2	91.5	GO:0036128	CatSper complex(GO:0036128)
10.2	20.3	GO:0031088	platelet dense granule membrane(GO:0031088)
10.1	20.2	GO:0031264	death-inducing signaling complex(GO:0031264)
10.0	110.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
10.0	30.0	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
10.0	20.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
9.9	29.8	GO:0044611	nuclear pore inner ring(GO:0044611)
9.9	266.9	GO:0005905	clathrin-coated pit(GO:0005905)
9.9	108.7	GO:0051233	spindle midzone(GO:0051233)
9.8	78.6	GO:0031616	spindle pole centrosome(GO:0031616)
9.8	9.8	GO:0031902	late endosome membrane(GO:0031902)
9.8	9.8	GO:0097422	tubular endosome(GO:0097422)
9.8	48.8	GO:0045179	apical cortex(GO:0045179)
9.8	107.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
9.7	9.7	GO:0061574	ASAP complex(GO:0061574)
9.6	67.4	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
9.6	11740.7	GO:0005654	nucleoplasm(GO:0005654)
9.6	458.7	GO:0044439	microbody part(GO:0044438) peroxisomal part(GO:0044439)
9.5	76.0	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
9.5	28.4	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
9.4	37.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
9.4	188.0	GO:0000785	chromatin(GO:0000785)
9.3	84.0	GO:1902554	serine/threonine protein kinase complex(GO:1902554)
9.3	65.1	GO:0043020	NADPH oxidase complex(GO:0043020)
9.3	18.5	GO:0000814	ESCRT II complex(GO:0000814)
9.3	9.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
9.2	129.4	GO:0005605	basal lamina(GO:0005605)
9.2	202.0	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
9.2	27.5	GO:0061689	tricellular tight junction(GO:0061689)
9.1	27.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
9.1	27.3	GO:0071953	elastic fiber(GO:0071953)
9.1	9.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
9.1	126.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
9.0	27.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
9.0	126.2	GO:0030904	retromer complex(GO:0030904)
9.0	35.9	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
9.0	53.9	GO:0042599	lamellar body(GO:0042599)
8.9	62.5	GO:0000813	ESCRT I complex(GO:0000813)
8.9	17.8	GO:0005577	fibrinogen complex(GO:0005577)
8.9	825.9	GO:0031965	nuclear membrane(GO:0031965)
8.8	35.3	GO:0043601	nuclear replisome(GO:0043601)
8.8	227.7	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
8.7	391.6	GO:0016529	sarcoplasmic reticulum(GO:0016529)
8.7	156.2	GO:0005801	cis-Golgi network(GO:0005801)
8.7	147.3	GO:0030992	intraciliary transport particle B(GO:0030992)
8.6	1053.0	GO:0005667	transcription factor complex(GO:0005667)
8.6	17.3	GO:0034399	nuclear periphery(GO:0034399)
8.6	17.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
8.5	238.8	GO:0016459	myosin complex(GO:0016459)
8.5	127.9	GO:0055038	recycling endosome membrane(GO:0055038)
8.5	50.9	GO:0034464	BBSome(GO:0034464)
8.5	110.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
8.5	59.3	GO:0005861	troponin complex(GO:0005861)
8.5	84.6	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
8.4	125.7	GO:0097228	sperm principal piece(GO:0097228)
8.3	66.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
8.3	24.9	GO:0089701	U2AF(GO:0089701)
8.3	83.1	GO:0008180	COP9 signalosome(GO:0008180)
8.3	8.3	GO:0042827	platelet dense granule(GO:0042827)
8.3	58.1	GO:0046581	intercellular canaliculus(GO:0046581)
8.3	414.7	GO:0030139	endocytic vesicle(GO:0030139)
8.2	73.7	GO:0001891	phagocytic cup(GO:0001891)
8.1	24.4	GO:0071439	clathrin complex(GO:0071439)
8.0	32.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
8.0	16.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
8.0	23.9	GO:0033596	TSC1-TSC2 complex(GO:0033596)
7.9	7.9	GO:0044316	cone cell pedicle(GO:0044316)
7.8	54.8	GO:0033263	CORVET complex(GO:0033263)
7.8	85.8	GO:0009925	basal plasma membrane(GO:0009925)
7.8	15.6	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
7.7	38.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
7.7	208.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
7.7	7.7	GO:0070419	nonhomologous end joining complex(GO:0070419)
7.7	138.3	GO:0001772	immunological synapse(GO:0001772)
7.7	7.7	GO:0032585	multivesicular body membrane(GO:0032585)
7.7	7.7	GO:0043219	lateral loop(GO:0043219)
7.6	7.6	GO:0030289	protein phosphatase 4 complex(GO:0030289)
7.6	296.1	GO:0005902	microvillus(GO:0005902)
7.5	98.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
7.5	22.6	GO:0031090	organelle membrane(GO:0031090)
7.5	30.0	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
7.4	7.4	GO:0030991	intraciliary transport particle A(GO:0030991)
7.4	717.5	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
7.4	29.5	GO:0036452	ESCRT complex(GO:0036452)
7.4	22.1	GO:0042583	chromaffin granule(GO:0042583)
7.4	22.1	GO:0005833	hemoglobin complex(GO:0005833)
7.3	95.4	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
7.2	21.7	GO:0070761	pre-snoRNP complex(GO:0070761)
7.2	57.9	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
7.2	187.8	GO:0030496	midbody(GO:0030496)
7.1	56.8	GO:0017119	Golgi transport complex(GO:0017119)
7.1	191.3	GO:0005844	polysome(GO:0005844)
7.1	42.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
7.1	105.8	GO:0034451	centriolar satellite(GO:0034451)
7.0	14.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
7.0	7.0	GO:0071437	invadopodium(GO:0071437)
7.0	174.4	GO:0016328	lateral plasma membrane(GO:0016328)
6.9	20.8	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
6.9	6.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
6.9	249.2	GO:0000502	proteasome complex(GO:0000502)
6.9	41.5	GO:0010008	endosome membrane(GO:0010008)
6.8	143.5	GO:0055037	recycling endosome(GO:0055037)
6.8	6.8	GO:0033270	paranode region of axon(GO:0033270)
6.8	345.0	GO:0005938	cell cortex(GO:0005938)
6.8	1128.2	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
6.7	6.7	GO:0031428	box C/D snoRNP complex(GO:0031428)
6.7	268.5	GO:0005795	Golgi stack(GO:0005795)
6.7	13.4	GO:0005896	interleukin-6 receptor complex(GO:0005896)
6.7	13.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
6.7	6.7	GO:0005686	U2 snRNP(GO:0005686)
6.6	6.6	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
6.6	2077.8	GO:0005730	nucleolus(GO:0005730)
6.6	19.8	GO:0071797	LUBAC complex(GO:0071797)
6.6	72.3	GO:0008305	integrin complex(GO:0008305)
6.6	46.0	GO:0030667	secretory granule membrane(GO:0030667)
6.6	13.1	GO:0000243	commitment complex(GO:0000243)
6.5	19.4	GO:0030055	cell-substrate junction(GO:0030055)
6.4	58.0	GO:0030663	COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
6.4	206.3	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
6.4	25.8	GO:0000938	GARP complex(GO:0000938)
6.3	6.3	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
6.3	125.3	GO:0035869	ciliary transition zone(GO:0035869)
6.3	12.5	GO:0046930	pore complex(GO:0046930)
6.2	6.2	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141)
6.2	37.5	GO:0097225	sperm midpiece(GO:0097225)
6.2	6.2	GO:0016272	prefoldin complex(GO:0016272)
6.2	24.9	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
6.2	55.9	GO:0036379	myofilament(GO:0036379)
6.2	4521.4	GO:0005829	cytosol(GO:0005829)
6.2	24.7	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
6.1	18.4	GO:0031501	mannosyltransferase complex(GO:0031501)
6.1	12.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
6.1	60.5	GO:0005657	replication fork(GO:0005657)
6.0	66.5	GO:0002080	acrosomal membrane(GO:0002080)
6.0	12.0	GO:1990391	DNA repair complex(GO:1990391)
6.0	29.9	GO:0034364	high-density lipoprotein particle(GO:0034364)
5.9	23.8	GO:0032591	dendritic spine membrane(GO:0032591)
5.9	17.7	GO:0005697	telomerase holoenzyme complex(GO:0005697)
5.8	325.7	GO:0005681	spliceosomal complex(GO:0005681)
5.8	260.6	GO:0016323	basolateral plasma membrane(GO:0016323)
5.7	11.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
5.7	5.7	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
5.7	34.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
5.7	279.5	GO:0005903	brush border(GO:0005903)
5.7	11.4	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
5.6	16.8	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
5.6	5.6	GO:0016342	catenin complex(GO:0016342)
5.5	355.3	GO:0072562	blood microparticle(GO:0072562)
5.4	16.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
5.4	136.1	GO:0031514	motile cilium(GO:0031514)
5.4	304.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
5.4	6444.9	GO:0070062	extracellular exosome(GO:0070062)
5.4	118.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
5.3	352.9	GO:0005815	microtubule organizing center(GO:0005815)
5.3	181.8	GO:0005814	centriole(GO:0005814)
5.3	555.5	GO:0005694	chromosome(GO:0005694)
5.2	522.3	GO:0070013	intracellular organelle lumen(GO:0070013)
5.2	1026.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
5.1	35.8	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
5.1	10.2	GO:0042555	MCM complex(GO:0042555)
5.1	25.4	GO:0036157	outer dynein arm(GO:0036157)
5.1	207.5	GO:0005769	early endosome(GO:0005769)
5.0	2110.9	GO:0005739	mitochondrion(GO:0005739)
5.0	5.0	GO:0008275	gamma-tubulin small complex(GO:0008275)
4.9	34.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
4.9	63.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
4.9	53.5	GO:0000922	spindle pole(GO:0000922)
4.9	9118.7	GO:0005634	nucleus(GO:0005634)
4.9	4.9	GO:0097255	R2TP complex(GO:0097255)
4.8	14.5	GO:0044853	plasma membrane raft(GO:0044853)
4.7	9.4	GO:0045098	type III intermediate filament(GO:0045098)
4.5	18.1	GO:0016234	inclusion body(GO:0016234)
4.4	13.2	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
4.4	4.4	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
4.2	4.2	GO:0044440	endosomal part(GO:0044440)
4.2	12.6	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
4.1	240.3	GO:0005874	microtubule(GO:0005874)
4.1	12.2	GO:0046691	intracellular canaliculus(GO:0046691)
4.0	4.0	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
3.9	3.9	GO:0016528	sarcoplasm(GO:0016528)
3.8	103.3	GO:0001750	photoreceptor outer segment(GO:0001750)
3.8	15.1	GO:0043218	compact myelin(GO:0043218)
3.4	75.5	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
3.3	1688.5	GO:0005783	endoplasmic reticulum(GO:0005783)
3.2	6.4	GO:0097546	ciliary base(GO:0097546)
3.2	6.3	GO:0005774	vacuolar membrane(GO:0005774)
3.1	83.6	GO:0043231	intracellular membrane-bounded organelle(GO:0043231)
3.0	80.9	GO:0031984	organelle subcompartment(GO:0031984) Golgi subcompartment(GO:0098791)
3.0	8.9	GO:0098858	actin-based cell projection(GO:0098858)
3.0	6.0	GO:0005771	multivesicular body(GO:0005771)
3.0	98.0	GO:0045177	apical part of cell(GO:0045177)
2.9	17.6	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
2.8	8.5	GO:0032426	stereocilium tip(GO:0032426)
2.8	2.8	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
2.8	64.9	GO:0070160	occluding junction(GO:0070160)
2.8	49.7	GO:0045095	keratin filament(GO:0045095)
2.7	2.7	GO:1990716	axonemal central apparatus(GO:1990716)
2.7	2.7	GO:0070695	FHF complex(GO:0070695)
2.7	344.8	GO:0009897	external side of plasma membrane(GO:0009897)
2.6	2.6	GO:0045171	intercellular bridge(GO:0045171)
2.5	20.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
2.5	17.5	GO:0005798	Golgi-associated vesicle(GO:0005798)
2.5	2.5	GO:0019815	B cell receptor complex(GO:0019815)
2.4	3541.3	GO:0005737	cytoplasm(GO:0005737)
2.2	45.4	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
2.2	36.6	GO:0005604	basement membrane(GO:0005604)
2.1	2.1	GO:0030312	external encapsulating structure(GO:0030312)
1.8	176.8	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
1.7	1.7	GO:0042613	MHC class II protein complex(GO:0042613)
1.4	1.4	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.3	3.8	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.8	8.5	GO:0005614	interstitial matrix(GO:0005614)
0.7	266.8	GO:0005615	extracellular space(GO:0005615)
0.4	166.6	GO:0005576	extracellular region(GO:0005576)
0.1	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.0	GO:0001533	cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
64.8	64.8	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
55.6	166.9	GO:0070644	vitamin D response element binding(GO:0070644)
54.2	216.6	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
53.1	159.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
51.1	204.3	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
50.3	150.9	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
46.6	279.6	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
43.5	130.6	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
43.3	129.9	GO:0042030	ATPase inhibitor activity(GO:0042030)
41.2	164.8	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
40.8	40.8	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
40.2	281.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
39.2	196.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
39.1	117.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
35.2	35.2	GO:0042296	ISG15 transferase activity(GO:0042296)
33.5	267.9	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
33.4	133.7	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
33.3	33.3	GO:0016420	S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
33.2	99.6	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
33.2	697.0	GO:0031492	nucleosomal DNA binding(GO:0031492)
32.8	295.4	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
32.1	32.1	GO:0035174	histone serine kinase activity(GO:0035174)
31.8	127.4	GO:0009374	biotin binding(GO:0009374)
31.3	94.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
31.0	93.0	GO:1990188	euchromatin binding(GO:1990188)
30.3	90.8	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
30.0	90.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
30.0	60.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
29.8	29.8	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
29.6	29.6	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
28.4	113.5	GO:0031493	nucleosomal histone binding(GO:0031493)
28.3	28.3	GO:0033677	DNA/RNA helicase activity(GO:0033677)
27.9	83.7	GO:0050692	DBD domain binding(GO:0050692)
27.7	138.7	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
27.6	82.9	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
27.6	165.6	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
27.1	108.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
26.7	320.9	GO:0017166	vinculin binding(GO:0017166)
26.6	239.5	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
26.4	290.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
26.3	78.9	GO:0004359	glutaminase activity(GO:0004359)
26.0	130.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
26.0	103.8	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
25.7	102.9	GO:0042731	PH domain binding(GO:0042731)
25.6	76.7	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
25.5	101.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
25.5	305.5	GO:0044548	S100 protein binding(GO:0044548)
25.2	75.7	GO:0048030	disaccharide binding(GO:0048030)
25.2	201.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
25.1	100.3	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
25.0	25.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
24.9	124.6	GO:0051525	NFAT protein binding(GO:0051525)
24.6	49.2	GO:0098821	BMP receptor activity(GO:0098821)
24.5	98.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
24.4	97.7	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
24.4	73.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
24.1	24.1	GO:0050693	LBD domain binding(GO:0050693)
23.8	71.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
23.8	71.3	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
23.8	95.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
23.6	94.5	GO:0004046	aminoacylase activity(GO:0004046)
23.5	70.4	GO:0070410	co-SMAD binding(GO:0070410)
23.4	70.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
23.4	281.0	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
23.3	70.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
23.3	139.9	GO:0001727	lipid kinase activity(GO:0001727)
23.3	69.9	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
22.9	389.4	GO:0046965	retinoid X receptor binding(GO:0046965)
22.8	114.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
22.6	90.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
22.6	294.1	GO:0008432	JUN kinase binding(GO:0008432)
22.6	90.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
22.6	67.7	GO:0019961	interferon binding(GO:0019961)
22.5	112.3	GO:1990239	steroid hormone binding(GO:1990239)
22.4	67.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
22.4	112.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
22.4	672.1	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
21.9	43.8	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
21.5	64.6	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
21.5	258.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
21.5	21.5	GO:0031852	mu-type opioid receptor binding(GO:0031852)
21.4	107.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
21.4	299.4	GO:0008307	structural constituent of muscle(GO:0008307)
21.4	42.7	GO:0042809	vitamin D receptor binding(GO:0042809)
21.3	85.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
21.3	191.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
21.3	85.1	GO:0031720	haptoglobin binding(GO:0031720)
21.2	85.0	GO:1990715	mRNA CDS binding(GO:1990715)
21.2	297.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
21.2	84.7	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
21.0	84.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
20.9	104.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
20.9	208.7	GO:0048185	activin binding(GO:0048185)
20.7	103.3	GO:0070061	fructose binding(GO:0070061)
20.5	472.0	GO:0019206	nucleoside kinase activity(GO:0019206)
20.5	225.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
20.3	40.5	GO:0030519	snoRNP binding(GO:0030519)
20.2	181.9	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
20.2	40.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
20.1	60.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
20.0	140.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
19.9	259.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
19.9	218.5	GO:0017154	semaphorin receptor activity(GO:0017154)
19.9	79.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
19.8	19.8	GO:0000009	alpha-1,6-mannosyltransferase activity(GO:0000009)
19.8	79.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
19.6	58.9	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
19.6	117.3	GO:0019855	calcium channel inhibitor activity(GO:0019855)
19.5	58.6	GO:0061665	SUMO ligase activity(GO:0061665)
19.5	78.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
19.5	175.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
19.4	116.5	GO:0008420	CTD phosphatase activity(GO:0008420)
19.4	252.1	GO:0008143	poly(A) binding(GO:0008143)
19.4	58.2	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
19.4	232.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)
19.3	38.6	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
19.2	96.2	GO:0045505	dynein intermediate chain binding(GO:0045505)
19.2	57.5	GO:0055100	adiponectin binding(GO:0055100)
18.9	94.7	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
18.9	75.8	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
18.7	74.9	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
18.7	74.8	GO:0042015	interleukin-20 binding(GO:0042015)
18.7	243.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
18.6	93.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
18.6	18.6	GO:0004559	alpha-mannosidase activity(GO:0004559)
18.6	74.3	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
18.5	129.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
18.5	55.4	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
18.4	55.3	GO:0031491	nucleosome binding(GO:0031491)
18.4	92.1	GO:0017040	ceramidase activity(GO:0017040)
18.4	18.4	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
18.4	257.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
18.3	91.5	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
18.2	36.5	GO:0070878	primary miRNA binding(GO:0070878)
18.2	54.7	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
18.2	127.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
18.2	54.7	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
18.0	415.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
18.0	54.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
18.0	288.0	GO:0017049	GTP-Rho binding(GO:0017049)
18.0	126.0	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
18.0	71.9	GO:0002060	purine nucleobase binding(GO:0002060)
17.9	125.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
17.9	357.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
17.9	71.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
17.8	35.6	GO:0030911	TPR domain binding(GO:0030911)
17.8	17.8	GO:0051434	BH3 domain binding(GO:0051434)
17.7	106.4	GO:0004311	farnesyltranstransferase activity(GO:0004311)
17.6	17.6	GO:0043426	MRF binding(GO:0043426)
17.5	87.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
17.5	69.9	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
17.5	52.4	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
17.3	121.3	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
17.2	68.7	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
17.1	51.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
17.1	51.3	GO:0005119	smoothened binding(GO:0005119)
16.9	101.7	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
16.9	84.7	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
16.9	50.8	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
16.9	84.3	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
16.6	33.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
16.6	66.4	GO:0042974	retinoic acid receptor binding(GO:0042974)
16.6	66.3	GO:0038132	neuregulin binding(GO:0038132)
16.5	82.4	GO:0019960	C-X3-C chemokine binding(GO:0019960)
16.5	82.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
16.4	49.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
16.4	49.3	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
16.4	687.3	GO:0070491	repressing transcription factor binding(GO:0070491)
16.4	98.2	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
16.3	48.8	GO:0004103	choline kinase activity(GO:0004103)
16.2	65.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
16.1	64.5	GO:0008430	selenium binding(GO:0008430)
16.1	16.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
16.1	64.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
16.1	48.3	GO:0035184	histone threonine kinase activity(GO:0035184)
16.1	32.2	GO:0016841	ammonia-lyase activity(GO:0016841)
16.0	32.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
16.0	80.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
16.0	32.0	GO:0004104	cholinesterase activity(GO:0004104)
16.0	80.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
16.0	143.8	GO:0032452	histone demethylase activity(GO:0032452)
15.9	127.5	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
15.9	63.7	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
15.9	15.9	GO:0003696	satellite DNA binding(GO:0003696)
15.9	47.6	GO:0003987	acetate-CoA ligase activity(GO:0003987)
15.8	15.8	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
15.8	346.5	GO:0001221	transcription cofactor binding(GO:0001221)
15.7	47.1	GO:0019770	IgG receptor activity(GO:0019770)
15.7	125.3	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
15.6	46.9	GO:0034186	apolipoprotein A-I binding(GO:0034186)
15.6	46.8	GO:0005128	erythropoietin receptor binding(GO:0005128)
15.5	46.5	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
15.5	46.4	GO:0030350	iron-responsive element binding(GO:0030350)
15.4	46.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
15.3	122.4	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
15.2	121.3	GO:0019789	SUMO transferase activity(GO:0019789)
15.1	15.1	GO:0016417	S-acyltransferase activity(GO:0016417)
15.1	15.1	GO:0045503	dynein light chain binding(GO:0045503)
15.1	211.7	GO:0050681	androgen receptor binding(GO:0050681)
15.0	45.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
15.0	44.9	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
14.9	74.7	GO:0004668	protein-arginine deiminase activity(GO:0004668)
14.9	432.2	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
14.9	193.2	GO:0005521	lamin binding(GO:0005521)
14.8	74.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
14.8	44.5	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
14.8	326.0	GO:0005158	insulin receptor binding(GO:0005158)
14.8	88.7	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
14.8	206.9	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
14.8	73.8	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
14.7	59.0	GO:0043515	kinetochore binding(GO:0043515)
14.7	132.4	GO:0016832	aldehyde-lyase activity(GO:0016832)
14.7	73.5	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
14.7	44.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
14.6	175.7	GO:0005123	death receptor binding(GO:0005123)
14.6	58.4	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558)
14.5	551.9	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
14.5	101.6	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
14.5	115.7	GO:0051766	inositol trisphosphate kinase activity(GO:0051766)
14.4	28.9	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
14.4	172.7	GO:0000400	four-way junction DNA binding(GO:0000400)
14.3	71.7	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
14.3	71.7	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
14.3	128.6	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
14.3	57.1	GO:0019237	centromeric DNA binding(GO:0019237)
14.2	42.7	GO:1990226	histone methyltransferase binding(GO:1990226)
14.2	28.5	GO:0016748	succinyltransferase activity(GO:0016748)
14.2	14.2	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673) peptide transmembrane transporter activity(GO:1904680)
14.2	56.7	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
14.2	56.7	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
14.1	42.4	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
14.1	56.2	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
14.0	28.1	GO:0030172	troponin C binding(GO:0030172)
14.0	56.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
14.0	14.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
14.0	56.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
14.0	112.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
13.9	223.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
13.9	138.9	GO:0035497	cAMP response element binding(GO:0035497)
13.9	125.0	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
13.9	55.5	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
13.8	276.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
13.8	855.0	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
13.8	179.1	GO:0070300	phosphatidic acid binding(GO:0070300)
13.7	95.9	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
13.7	150.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
13.7	82.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
13.7	68.4	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
13.7	54.7	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
13.6	40.8	GO:0043559	insulin binding(GO:0043559)
13.6	54.4	GO:0032036	myosin heavy chain binding(GO:0032036)
13.6	40.8	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
13.6	13.6	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
13.5	81.3	GO:0030983	mismatched DNA binding(GO:0030983)
13.5	40.6	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
13.5	40.6	GO:0030515	snoRNA binding(GO:0030515)
13.5	54.0	GO:0015057	thrombin receptor activity(GO:0015057)
13.5	53.9	GO:0015232	heme transporter activity(GO:0015232)
13.5	40.4	GO:0031014	troponin T binding(GO:0031014)
13.5	26.9	GO:0031871	proteinase activated receptor binding(GO:0031871)
13.4	40.3	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
13.3	186.8	GO:0001618	virus receptor activity(GO:0001618)
13.3	160.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
13.3	53.3	GO:0015375	glycine:sodium symporter activity(GO:0015375)
13.3	13.3	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
13.3	26.5	GO:0004427	inorganic diphosphatase activity(GO:0004427)
13.3	199.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
13.3	53.0	GO:0034618	arginine binding(GO:0034618)
13.2	79.2	GO:0000182	rDNA binding(GO:0000182)
13.1	78.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
13.1	65.4	GO:0004301	epoxide hydrolase activity(GO:0004301)
13.1	26.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
13.1	13.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
13.1	65.3	GO:0015288	porin activity(GO:0015288)
13.1	39.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
12.9	38.8	GO:0031686	A1 adenosine receptor binding(GO:0031686)
12.9	25.9	GO:0070568	RNA guanylyltransferase activity(GO:0008192) guanylyltransferase activity(GO:0070568)
12.9	25.8	GO:0032552	deoxyribonucleotide binding(GO:0032552)
12.9	321.5	GO:0042162	telomeric DNA binding(GO:0042162)
12.8	12.8	GO:0019887	protein kinase regulator activity(GO:0019887)
12.8	12.8	GO:0042609	CD4 receptor binding(GO:0042609)
12.8	128.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
12.8	76.9	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
12.8	230.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
12.7	12.7	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
12.6	50.6	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
12.6	63.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
12.6	150.7	GO:0005372	water transmembrane transporter activity(GO:0005372)
12.5	37.5	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
12.5	162.5	GO:0034573	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
12.5	1111.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
12.5	87.3	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
12.4	87.0	GO:0035613	RNA stem-loop binding(GO:0035613)
12.4	74.4	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
12.4	37.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
12.4	37.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
12.4	37.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
12.3	221.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
12.3	209.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
12.3	12.3	GO:0031749	D2 dopamine receptor binding(GO:0031749)
12.3	356.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
12.2	134.7	GO:0032183	SUMO binding(GO:0032183)
12.2	232.4	GO:0015301	anion:anion antiporter activity(GO:0015301)
12.2	256.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
12.2	366.8	GO:0004402	histone acetyltransferase activity(GO:0004402)
12.2	158.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
12.2	12.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
12.2	24.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
12.2	24.3	GO:0043842	Kdo transferase activity(GO:0043842)
12.2	12.2	GO:0048156	tau protein binding(GO:0048156)
12.1	109.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
12.1	24.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
12.1	750.3	GO:0035326	enhancer binding(GO:0035326)
12.1	60.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
12.0	36.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
12.0	84.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
12.0	12.0	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
12.0	36.0	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
12.0	12.0	GO:0035173	histone kinase activity(GO:0035173)
12.0	35.9	GO:0016530	metallochaperone activity(GO:0016530)
11.9	23.9	GO:0051379	alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
11.9	178.4	GO:0045502	dynein binding(GO:0045502)
11.9	1150.8	GO:0017137	Rab GTPase binding(GO:0017137)
11.9	35.6	GO:0004064	arylesterase activity(GO:0004064)
11.8	106.5	GO:0031996	thioesterase binding(GO:0031996)
11.8	94.7	GO:0003993	acid phosphatase activity(GO:0003993)
11.8	141.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
11.8	35.3	GO:0032794	GTPase activating protein binding(GO:0032794)
11.7	46.7	GO:0070513	death domain binding(GO:0070513)
11.6	174.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
11.6	58.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
11.6	69.7	GO:0042043	neurexin family protein binding(GO:0042043)
11.6	23.2	GO:0030619	U1 snRNA binding(GO:0030619)
11.6	590.3	GO:0017048	Rho GTPase binding(GO:0017048)
11.6	81.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
11.5	23.1	GO:0030984	kininogen binding(GO:0030984)
11.5	115.1	GO:0004016	adenylate cyclase activity(GO:0004016)
11.5	11.5	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
11.5	218.2	GO:0003746	translation elongation factor activity(GO:0003746)
11.5	206.3	GO:0030507	spectrin binding(GO:0030507)
11.4	785.9	GO:0001047	core promoter binding(GO:0001047)
11.4	34.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
11.4	45.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
11.4	272.5	GO:0070063	RNA polymerase binding(GO:0070063)
11.4	22.7	GO:0042379	chemokine receptor binding(GO:0042379)
11.3	34.0	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
11.3	45.4	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
11.3	11.3	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
11.2	89.7	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
11.2	78.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
11.2	33.5	GO:0019002	GMP binding(GO:0019002)
11.1	688.8	GO:0031072	heat shock protein binding(GO:0031072)
11.1	77.4	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
11.0	44.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
11.0	22.0	GO:0031685	adenosine receptor binding(GO:0031685)
11.0	22.0	GO:0001069	regulatory region RNA binding(GO:0001069)
11.0	33.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
11.0	87.8	GO:0051010	microtubule plus-end binding(GO:0051010)
11.0	11.0	GO:0070538	oleic acid binding(GO:0070538)
10.9	21.8	GO:0051959	dynein light intermediate chain binding(GO:0051959)
10.8	10.8	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
10.8	313.5	GO:0035064	methylated histone binding(GO:0035064)
10.8	10.8	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
10.7	53.5	GO:0070728	leucine binding(GO:0070728)
10.6	42.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
10.6	53.2	GO:0005522	profilin binding(GO:0005522)
10.6	222.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
10.6	21.2	GO:0015928	fucosidase activity(GO:0015928)
10.5	31.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
10.5	84.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
10.5	84.0	GO:0070097	delta-catenin binding(GO:0070097)
10.5	21.0	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
10.5	10.5	GO:0008649	rRNA methyltransferase activity(GO:0008649) rRNA (uridine) methyltransferase activity(GO:0016436)
10.5	83.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
10.4	31.3	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
10.4	31.2	GO:0045134	uridine-diphosphatase activity(GO:0045134)
10.4	362.3	GO:0042826	histone deacetylase binding(GO:0042826)
10.3	196.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
10.3	866.8	GO:0003714	transcription corepressor activity(GO:0003714)
10.3	154.5	GO:0043130	ubiquitin binding(GO:0043130)
10.3	10.3	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
10.3	61.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
10.3	1374.0	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
10.2	61.4	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
10.2	51.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
10.2	184.0	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
10.2	71.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
10.2	132.6	GO:0051059	NF-kappaB binding(GO:0051059)
10.2	10.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
10.1	30.4	GO:0016018	cyclosporin A binding(GO:0016018)
10.1	70.7	GO:0003684	damaged DNA binding(GO:0003684)
10.1	181.2	GO:0001056	RNA polymerase III activity(GO:0001056)
10.1	100.5	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
10.0	40.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
10.0	30.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
10.0	20.0	GO:0045294	alpha-catenin binding(GO:0045294)
10.0	10.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
10.0	796.8	GO:0051015	actin filament binding(GO:0051015)
9.9	69.4	GO:0070412	R-SMAD binding(GO:0070412)
9.9	534.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
9.9	79.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
9.9	39.6	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
9.9	29.7	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
9.9	49.4	GO:0005536	glucose binding(GO:0005536)
9.8	9.8	GO:0005047	signal recognition particle binding(GO:0005047)
9.8	19.5	GO:0030274	LIM domain binding(GO:0030274)
9.8	29.3	GO:1990405	protein antigen binding(GO:1990405)
9.8	117.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
9.7	19.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
9.7	9.7	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
9.7	875.1	GO:0008766	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
9.7	9.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
9.7	67.8	GO:0019957	C-C chemokine binding(GO:0019957)
9.7	9.7	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
9.7	58.0	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
9.7	19.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
9.7	19.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
9.6	202.1	GO:0008536	Ran GTPase binding(GO:0008536)
9.6	86.3	GO:0034522	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
9.6	28.7	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
9.5	66.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
9.5	19.0	GO:0051425	PTB domain binding(GO:0051425)
9.5	18.9	GO:0017089	glycolipid transporter activity(GO:0017089)
9.5	246.3	GO:0015485	cholesterol binding(GO:0015485)
9.5	56.7	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
9.5	37.8	GO:0052794	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
9.4	56.7	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
9.4	37.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
9.4	47.0	GO:0016936	galactoside binding(GO:0016936)
9.4	18.8	GO:0070569	uridylyltransferase activity(GO:0070569)
9.3	46.6	GO:0018654	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
9.3	83.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
9.3	158.3	GO:0001848	complement binding(GO:0001848)
9.3	92.8	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
9.2	37.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
9.2	18.4	GO:0071987	WD40-repeat domain binding(GO:0071987)
9.1	164.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
9.1	355.2	GO:0042393	histone binding(GO:0042393)
9.1	18.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
9.1	45.5	GO:0004957	prostaglandin E receptor activity(GO:0004957)
9.1	18.2	GO:0000405	bubble DNA binding(GO:0000405)
9.1	27.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
9.1	36.4	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
9.1	81.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
9.0	560.4	GO:0003713	transcription coactivator activity(GO:0003713)
9.0	27.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
9.0	180.6	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
9.0	45.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
8.9	80.4	GO:0034843	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
8.9	26.8	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
8.9	17.8	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
8.9	80.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
8.9	17.8	GO:0031721	hemoglobin alpha binding(GO:0031721)
8.9	204.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
8.9	44.5	GO:0050321	tau-protein kinase activity(GO:0050321)
8.9	26.7	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
8.8	79.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
8.8	44.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
8.8	281.4	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
8.8	26.4	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
8.8	123.0	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
8.8	43.8	GO:0008097	5S rRNA binding(GO:0008097)
8.8	17.5	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
8.8	332.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
8.7	26.2	GO:0043199	sulfate binding(GO:0043199)
8.7	26.2	GO:0005534	galactose binding(GO:0005534)
8.7	17.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
8.6	95.1	GO:0010181	FMN binding(GO:0010181)
8.6	17.3	GO:0005131	growth hormone receptor binding(GO:0005131)
8.6	43.0	GO:1990446	U1 snRNP binding(GO:1990446)
8.6	34.4	GO:0005113	patched binding(GO:0005113)
8.6	34.3	GO:0070403	NAD+ binding(GO:0070403)
8.5	34.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
8.5	536.9	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
8.5	68.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
8.5	93.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
8.5	50.9	GO:0042301	phosphate ion binding(GO:0042301)
8.5	8.5	GO:0031690	adrenergic receptor binding(GO:0031690)
8.5	33.9	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
8.4	244.8	GO:0005484	SNAP receptor activity(GO:0005484)
8.4	16.7	GO:0001055	RNA polymerase II activity(GO:0001055)
8.4	8.4	GO:0043546	molybdopterin cofactor binding(GO:0043546)
8.4	50.2	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
8.3	16.7	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
8.3	33.3	GO:0070051	fibrinogen binding(GO:0070051)
8.3	24.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
8.3	174.1	GO:0043236	laminin binding(GO:0043236)
8.3	1183.9	GO:0008134	transcription factor binding(GO:0008134)
8.2	16.4	GO:0000171	ribonuclease MRP activity(GO:0000171)
8.2	90.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
8.2	90.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
8.1	358.0	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
8.1	40.6	GO:0043008	ATP-dependent protein binding(GO:0043008)
8.1	16.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
8.1	40.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
8.0	72.4	GO:0060590	ATPase regulator activity(GO:0060590)
8.0	48.3	GO:0008172	S-methyltransferase activity(GO:0008172)
8.0	64.2	GO:0008327	methyl-CpG binding(GO:0008327)
8.0	72.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
8.0	88.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
8.0	95.9	GO:0016854	racemase and epimerase activity(GO:0016854)
8.0	103.6	GO:0008198	ferrous iron binding(GO:0008198)
8.0	23.9	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
7.9	23.8	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
7.9	7.9	GO:0004096	catalase activity(GO:0004096)
7.9	15.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
7.9	78.7	GO:0045296	cadherin binding(GO:0045296)
7.9	39.3	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
7.8	15.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
7.8	39.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
7.8	31.3	GO:0035197	siRNA binding(GO:0035197)
7.8	187.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
7.8	23.4	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
7.8	85.5	GO:0017091	AU-rich element binding(GO:0017091)
7.7	294.0	GO:0051020	GTPase binding(GO:0051020)
7.7	30.9	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
7.7	54.0	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
7.7	23.1	GO:0008266	poly(U) RNA binding(GO:0008266)
7.7	53.9	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
7.7	76.9	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
7.7	23.0	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
7.7	7.7	GO:0070573	metallodipeptidase activity(GO:0070573)
7.6	68.7	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
7.6	15.3	GO:0031369	translation initiation factor binding(GO:0031369)
7.6	83.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
7.6	1309.3	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
7.6	7.6	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
7.6	53.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
7.6	53.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
7.5	37.6	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
7.5	7.5	GO:0005275	amine transmembrane transporter activity(GO:0005275)
7.5	262.8	GO:0003697	single-stranded DNA binding(GO:0003697)
7.5	15.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
7.5	44.9	GO:0070891	lipoteichoic acid binding(GO:0070891)
7.5	22.4	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
7.4	44.6	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
7.4	141.1	GO:0008483	transaminase activity(GO:0008483)
7.4	215.2	GO:0030674	protein binding, bridging(GO:0030674)
7.4	22.1	GO:0034511	U3 snoRNA binding(GO:0034511)
7.4	154.4	GO:0008748	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
7.3	14.7	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
7.3	22.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
7.3	14.6	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
7.3	87.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
7.3	36.4	GO:0043014	alpha-tubulin binding(GO:0043014)
7.3	21.8	GO:0070492	oligosaccharide binding(GO:0070492)
7.3	138.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
7.2	137.7	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
7.2	43.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
7.2	64.7	GO:0016504	peptidase activator activity(GO:0016504)
7.2	43.1	GO:0016778	diphosphotransferase activity(GO:0016778)
7.2	35.9	GO:0002039	p53 binding(GO:0002039)
7.2	100.4	GO:0003712	transcription cofactor activity(GO:0003712)
7.2	14.3	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
7.1	78.6	GO:0048038	quinone binding(GO:0048038)
7.1	142.8	GO:0048487	beta-tubulin binding(GO:0048487)
7.1	142.6	GO:0043621	protein self-association(GO:0043621)
7.1	56.9	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
7.1	21.3	GO:0004771	sterol esterase activity(GO:0004771)
7.1	35.5	GO:0043422	protein kinase B binding(GO:0043422)
7.0	295.7	GO:0003743	translation initiation factor activity(GO:0003743)
7.0	21.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
7.0	490.4	GO:0017124	SH3 domain binding(GO:0017124)
7.0	27.8	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
7.0	132.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
6.9	69.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
6.9	27.5	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
6.9	20.6	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
6.8	13.7	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
6.8	20.3	GO:0019808	polyamine binding(GO:0019808)
6.8	155.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
6.8	108.1	GO:0004177	aminopeptidase activity(GO:0004177)
6.7	13.5	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
6.7	20.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
6.7	107.8	GO:0070008	serine-type exopeptidase activity(GO:0070008)
6.7	6.7	GO:0050815	phosphoserine binding(GO:0050815)
6.7	20.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
6.7	20.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
6.7	6.7	GO:0030492	hemoglobin binding(GO:0030492)
6.7	13.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
6.7	13.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
6.7	399.6	GO:0005178	integrin binding(GO:0005178)
6.7	20.0	GO:0008131	primary amine oxidase activity(GO:0008131)
6.6	86.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
6.6	13.3	GO:0004945	angiotensin type II receptor activity(GO:0004945)
6.6	46.2	GO:0035325	Toll-like receptor binding(GO:0035325)
6.6	151.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
6.6	19.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
6.5	6.5	GO:0070698	type I activin receptor binding(GO:0070698)
6.5	45.3	GO:0097602	cullin family protein binding(GO:0097602)
6.5	45.2	GO:0071889	14-3-3 protein binding(GO:0071889)
6.4	64.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
6.4	32.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
6.4	38.4	GO:0034185	apolipoprotein binding(GO:0034185)
6.4	6.4	GO:0097642	calcitonin family receptor activity(GO:0097642)
6.4	76.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
6.4	25.4	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
6.3	38.1	GO:0008408	3'-5' exonuclease activity(GO:0008408)
6.3	113.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
6.3	592.8	GO:0003735	structural constituent of ribosome(GO:0003735)
6.3	6.3	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
6.3	6.3	GO:0030371	translation repressor activity(GO:0030371)
6.3	144.0	GO:0019107	myristoyltransferase activity(GO:0019107)
6.2	18.7	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
6.2	24.9	GO:0031419	cobalamin binding(GO:0031419)
6.2	62.3	GO:0031489	myosin V binding(GO:0031489)
6.2	6.2	GO:0008135	translation factor activity, RNA binding(GO:0008135)
6.2	12.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
6.2	12.4	GO:0019215	intermediate filament binding(GO:0019215)
6.2	6.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
6.2	24.7	GO:0016208	AMP binding(GO:0016208)
6.2	61.6	GO:0004806	triglyceride lipase activity(GO:0004806)
6.2	18.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
6.2	30.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
6.2	18.5	GO:0016833	oxo-acid-lyase activity(GO:0016833)
6.2	129.2	GO:0050699	WW domain binding(GO:0050699)
6.1	18.4	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
6.1	12.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
6.1	12.3	GO:0000104	succinate dehydrogenase activity(GO:0000104)
6.1	18.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
6.1	24.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
6.1	360.0	GO:0004536	deoxyribonuclease activity(GO:0004536)
6.1	200.2	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
6.1	6.1	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
6.0	6.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
6.0	18.0	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
6.0	29.9	GO:0016409	palmitoyltransferase activity(GO:0016409)
6.0	17.9	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
6.0	59.7	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
6.0	113.4	GO:0008276	protein methyltransferase activity(GO:0008276)
6.0	47.7	GO:0038191	neuropilin binding(GO:0038191)
5.9	17.8	GO:0016015	morphogen activity(GO:0016015)
5.9	76.7	GO:0016866	intramolecular transferase activity(GO:0016866)
5.9	29.4	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
5.9	3785.6	GO:0044822	poly(A) RNA binding(GO:0044822)
5.8	40.9	GO:0039706	co-receptor binding(GO:0039706)
5.8	11.7	GO:0034452	dynactin binding(GO:0034452)
5.8	157.1	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
5.8	209.4	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
5.8	11.6	GO:0015925	galactosidase activity(GO:0015925)
5.8	11.5	GO:0019213	deacetylase activity(GO:0019213)
5.8	34.6	GO:0034793	acyl-CoA ligase activity(GO:0003996) succinate-CoA ligase activity(GO:0004774) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
5.7	5.7	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
5.7	5.7	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
5.7	5.7	GO:0018589	fluorene oxygenase activity(GO:0018585) mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
5.6	11.3	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
5.6	27.8	GO:0005499	vitamin D binding(GO:0005499)
5.6	5.6	GO:0046790	virion binding(GO:0046790)
5.5	16.6	GO:0060090	binding, bridging(GO:0060090)
5.5	11.0	GO:0004126	cytidine deaminase activity(GO:0004126)
5.5	10.9	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
5.4	5.4	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
5.4	48.8	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
5.4	59.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
5.4	156.2	GO:0008168	methyltransferase activity(GO:0008168)
5.4	42.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
5.4	26.8	GO:0070628	proteasome binding(GO:0070628)
5.3	10.6	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
5.3	63.7	GO:0017022	myosin binding(GO:0017022)
5.3	5.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
5.3	21.1	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
5.3	73.8	GO:0051087	chaperone binding(GO:0051087)
5.3	26.3	GO:0050700	CARD domain binding(GO:0050700)
5.3	21.0	GO:0004594	pantothenate kinase activity(GO:0004594)
5.2	20.9	GO:0004566	beta-glucuronidase activity(GO:0004566)
5.2	15.6	GO:0005344	oxygen transporter activity(GO:0005344)
5.2	10.4	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
5.2	67.5	GO:0015238	drug transmembrane transporter activity(GO:0015238)
5.2	5.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
5.2	362.5	GO:0003774	motor activity(GO:0003774)
5.2	5.2	GO:0004386	helicase activity(GO:0004386)
5.2	15.5	GO:0051787	misfolded protein binding(GO:0051787)
5.2	217.3	GO:0008565	protein transporter activity(GO:0008565)
5.2	10.3	GO:0042895	antibiotic transporter activity(GO:0042895)
5.1	35.9	GO:0016836	hydro-lyase activity(GO:0016836)
5.1	553.4	GO:0008234	cysteine-type peptidase activity(GO:0008234)
5.1	10.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
5.1	15.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
5.1	15.2	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
5.0	15.1	GO:0046848	hydroxyapatite binding(GO:0046848)
5.0	1094.4	GO:0005525	GTP binding(GO:0005525)
5.0	115.7	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812)
5.0	5.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
5.0	10.1	GO:0055102	lipase inhibitor activity(GO:0055102)
5.0	75.2	GO:0031593	polyubiquitin binding(GO:0031593)
5.0	14.9	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
4.9	4077.9	GO:0003677	DNA binding(GO:0003677)
4.9	34.6	GO:0004622	lysophospholipase activity(GO:0004622)
4.9	44.4	GO:0000049	tRNA binding(GO:0000049)
4.9	24.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
4.9	4.9	GO:0038181	bile acid receptor activity(GO:0038181)
4.9	82.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
4.8	9.7	GO:0070034	telomerase RNA binding(GO:0070034)
4.8	159.5	GO:0004860	protein kinase inhibitor activity(GO:0004860)
4.8	48.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
4.8	58.0	GO:0019239	deaminase activity(GO:0019239)
4.8	28.8	GO:0070566	adenylyltransferase activity(GO:0070566)
4.8	9.6	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
4.8	14.3	GO:0038100	nodal binding(GO:0038100)
4.7	455.1	GO:0005096	GTPase activator activity(GO:0005096)
4.7	19.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
4.7	28.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
4.7	33.1	GO:0015245	fatty acid transporter activity(GO:0015245)
4.7	18.8	GO:0004966	galanin receptor activity(GO:0004966)
4.6	18.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
4.6	13.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
4.6	13.9	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
4.6	27.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
4.6	13.8	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
4.6	55.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
4.5	13.6	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
4.5	36.1	GO:0004568	chitinase activity(GO:0004568)
4.5	31.4	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
4.5	31.3	GO:0005548	phospholipid transporter activity(GO:0005548)
4.5	8.9	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
4.4	8.9	GO:0019870	potassium channel inhibitor activity(GO:0019870)
4.4	22.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
4.4	8.8	GO:0071253	connexin binding(GO:0071253)
4.4	21.9	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
4.4	4.4	GO:0019862	IgA binding(GO:0019862)
4.4	13.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
4.3	34.7	GO:0043022	ribosome binding(GO:0043022)
4.3	528.5	GO:0003779	actin binding(GO:0003779)
4.3	8.6	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
4.3	8.6	GO:0030881	beta-2-microglobulin binding(GO:0030881)
4.3	21.4	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
4.3	4.3	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
4.3	85.1	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
4.3	25.5	GO:0016878	acid-thiol ligase activity(GO:0016878)
4.2	114.6	GO:0005507	copper ion binding(GO:0005507)
4.2	21.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
4.2	105.7	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
4.2	79.9	GO:0008013	beta-catenin binding(GO:0008013)
4.2	16.8	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
4.2	12.5	GO:0070182	DNA polymerase binding(GO:0070182)
4.2	50.1	GO:0050840	extracellular matrix binding(GO:0050840)
4.2	33.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
4.2	41.6	GO:0004745	retinol dehydrogenase activity(GO:0004745)
4.2	8.3	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
4.1	12.4	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
4.1	20.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
4.1	16.3	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
4.1	12.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
4.0	1055.2	GO:0008270	zinc ion binding(GO:0008270)
4.0	20.2	GO:0031849	olfactory receptor binding(GO:0031849)
4.0	24.0	GO:0071813	lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
4.0	8.0	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
4.0	47.8	GO:0030215	semaphorin receptor binding(GO:0030215)
4.0	43.8	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
4.0	11.9	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
4.0	7.9	GO:0051185	coenzyme transporter activity(GO:0051185)
4.0	11.9	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
4.0	4.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
3.9	7.8	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
3.9	3.9	GO:0019187	beta-1,4-mannosyltransferase activity(GO:0019187)
3.9	3.9	GO:0005523	tropomyosin binding(GO:0005523)
3.9	11.6	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
3.8	111.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
3.8	7.7	GO:0017081	chloride channel regulator activity(GO:0017081)
3.8	3.8	GO:0016972	thiol oxidase activity(GO:0016972)
3.8	186.2	GO:0016853	isomerase activity(GO:0016853)
3.8	15.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
3.7	44.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
3.7	14.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
3.7	29.7	GO:0016790	thiolester hydrolase activity(GO:0016790)
3.7	14.8	GO:0005143	interleukin-12 receptor binding(GO:0005143)
3.7	169.6	GO:0004857	enzyme inhibitor activity(GO:0004857)
3.7	51.6	GO:0004623	phospholipase A2 activity(GO:0004623)
3.7	25.6	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
3.6	32.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.6	21.8	GO:0070700	BMP receptor binding(GO:0070700)
3.6	154.3	GO:0019902	phosphatase binding(GO:0019902)
3.6	35.9	GO:0043734	DNA-N1-methyladenine dioxygenase activity(GO:0043734)
3.6	21.5	GO:0019966	interleukin-1 binding(GO:0019966)
3.5	10.6	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
3.5	6.9	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
3.4	10.3	GO:0004967	glucagon receptor activity(GO:0004967)
3.4	6.9	GO:0035473	lipase binding(GO:0035473)
3.4	3.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
3.4	84.8	GO:0051723	protein methylesterase activity(GO:0051723)
3.4	125.2	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
3.4	10.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
3.4	6.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
3.3	26.6	GO:0042805	actinin binding(GO:0042805)
3.3	108.5	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
3.3	23.0	GO:0005506	iron ion binding(GO:0005506)
3.3	3.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
3.3	101.1	GO:0005132	type I interferon receptor binding(GO:0005132)
3.2	9.7	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
3.2	6.5	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
3.2	6.5	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
3.2	649.1	GO:0004175	endopeptidase activity(GO:0004175)
3.2	48.3	GO:0051117	ATPase binding(GO:0051117)
3.2	9.6	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
3.2	3.2	GO:0051920	peroxiredoxin activity(GO:0051920)
3.2	53.9	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
3.2	31.6	GO:0004521	endoribonuclease activity(GO:0004521)
3.1	77.9	GO:0005496	steroid binding(GO:0005496)
3.1	6.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
3.1	3.1	GO:0019956	chemokine binding(GO:0019956)
3.1	6.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
3.0	661.2	GO:0005198	structural molecule activity(GO:0005198)
3.0	36.4	GO:0022842	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
3.0	63.4	GO:0004518	nuclease activity(GO:0004518)
3.0	3.0	GO:0051373	FATZ binding(GO:0051373)
3.0	23.8	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
3.0	14.9	GO:0050431	transforming growth factor beta binding(GO:0050431)
3.0	8.9	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
2.9	29.3	GO:0015926	glucosidase activity(GO:0015926)
2.9	58.0	GO:0016830	carbon-carbon lyase activity(GO:0016830)
2.9	2.9	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
2.8	8.5	GO:0035257	nuclear hormone receptor binding(GO:0035257)
2.8	42.6	GO:0005537	mannose binding(GO:0005537)
2.8	5.7	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
2.8	2.8	GO:0019207	kinase regulator activity(GO:0019207)
2.8	8.4	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.8	8.4	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
2.8	11.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
2.8	2.8	GO:0019763	immunoglobulin receptor activity(GO:0019763)
2.8	11.1	GO:0015643	toxic substance binding(GO:0015643)
2.8	143.8	GO:0044389	ubiquitin-like protein ligase binding(GO:0044389)
2.8	278.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
2.8	22.1	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
2.7	13.7	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
2.7	2.7	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
2.7	5.5	GO:0015252	hydrogen ion channel activity(GO:0015252)
2.7	2.7	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
2.7	379.8	GO:0003676	nucleic acid binding(GO:0003676)
2.7	5.4	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
2.7	10.6	GO:0032451	demethylase activity(GO:0032451)
2.6	78.6	GO:0000149	SNARE binding(GO:0000149)
2.6	41.5	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
2.6	25.9	GO:0005243	gap junction channel activity(GO:0005243)
2.6	7.8	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429)
2.6	7.7	GO:0005502	11-cis retinal binding(GO:0005502)
2.6	15.4	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.5	91.0	GO:0015405	primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)
2.5	17.6	GO:0017134	fibroblast growth factor binding(GO:0017134)
2.5	2.5	GO:0070087	chromo shadow domain binding(GO:0070087)
2.5	15.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
2.5	2.5	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
2.5	39.6	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
2.5	170.2	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
2.5	2.5	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
2.4	317.2	GO:0005125	cytokine activity(GO:0005125)
2.4	2.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
2.4	16.6	GO:0043015	gamma-tubulin binding(GO:0043015)
2.4	54.5	GO:0016887	ATPase activity(GO:0016887)
2.3	6.9	GO:0001595	angiotensin receptor activity(GO:0001595)
2.3	13.8	GO:0005048	signal sequence binding(GO:0005048)
2.3	25.1	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
2.2	339.8	GO:0019899	enzyme binding(GO:0019899)
2.2	6.6	GO:0019864	IgG binding(GO:0019864)
2.2	8.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
2.1	8.6	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.1	4.2	GO:0008199	ferric iron binding(GO:0008199)
2.1	2.1	GO:0004461	lactose synthase activity(GO:0004461)
2.0	2.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
2.0	12.2	GO:0000287	magnesium ion binding(GO:0000287)
2.0	8.0	GO:0005540	hyaluronic acid binding(GO:0005540)
2.0	25.7	GO:0005044	scavenger receptor activity(GO:0005044)
2.0	3.9	GO:0043531	ADP binding(GO:0043531)
2.0	11.7	GO:0005000	vasopressin receptor activity(GO:0005000)
1.9	1.9	GO:0017098	sulfonylurea receptor binding(GO:0017098)
1.9	1.9	GO:0015665	alcohol transmembrane transporter activity(GO:0015665)
1.9	1.9	GO:0016415	octanoyltransferase activity(GO:0016415)
1.9	5.7	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
1.9	5.7	GO:0016783	sulfurtransferase activity(GO:0016783)
1.9	5.7	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
1.8	3.6	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
1.8	7.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
1.8	7.2	GO:0030145	manganese ion binding(GO:0030145)
1.8	7.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
1.8	9.0	GO:0042288	MHC class I protein binding(GO:0042288)
1.8	17.7	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
1.8	3.5	GO:0051870	methotrexate binding(GO:0051870)
1.7	1.7	GO:0015927	trehalase activity(GO:0015927)
1.7	1.7	GO:0001846	opsonin binding(GO:0001846)
1.7	5.1	GO:0019865	immunoglobulin binding(GO:0019865)
1.7	5.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
1.7	16.7	GO:0051287	NAD binding(GO:0051287)
1.6	11.4	GO:0003796	lysozyme activity(GO:0003796)
1.6	29.3	GO:0005319	lipid transporter activity(GO:0005319)
1.6	3.2	GO:0016595	glutamate binding(GO:0016595)
1.6	4.8	GO:0019976	interleukin-2 binding(GO:0019976)
1.5	38.7	GO:0008022	protein C-terminus binding(GO:0008022)
1.5	1.5	GO:0008158	hedgehog receptor activity(GO:0008158)
1.5	3.0	GO:0070402	NADPH binding(GO:0070402)
1.5	1.5	GO:0004645	phosphorylase activity(GO:0004645)
1.5	1.5	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
1.5	2.9	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
1.4	26.7	GO:0042605	peptide antigen binding(GO:0042605)
1.4	1.4	GO:0031404	chloride ion binding(GO:0031404)
1.3	51.3	GO:0008417	fucosyltransferase activity(GO:0008417)
1.3	3.9	GO:0004111	creatine kinase activity(GO:0004111)
1.2	2.5	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.2	9.8	GO:0004312	fatty acid synthase activity(GO:0004312)
1.2	1.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
1.1	4.5	GO:0030695	GTPase regulator activity(GO:0030695)
1.1	3.4	GO:0050780	dopamine receptor binding(GO:0050780)
1.1	3.4	GO:0008410	CoA-transferase activity(GO:0008410)
1.1	1.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.1	5.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
1.1	1.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
1.1	9.9	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
1.0	38.5	GO:0008527	taste receptor activity(GO:0008527)
1.0	3.8	GO:0004974	leukotriene receptor activity(GO:0004974)
0.9	82.9	GO:0019904	protein domain specific binding(GO:0019904)
0.9	1.8	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.9	97.1	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.9	10.6	GO:0003823	antigen binding(GO:0003823)
0.9	9.6	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.8	1.6	GO:0070064	proline-rich region binding(GO:0070064)
0.8	0.8	GO:0070052	collagen V binding(GO:0070052)
0.8	1.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.7	7.5	GO:0005112	Notch binding(GO:0005112)
0.7	3.5	GO:0031386	protein tag(GO:0031386)
0.7	61.5	GO:0030246	carbohydrate binding(GO:0030246)
0.6	0.6	GO:0048019	receptor antagonist activity(GO:0048019)
0.6	1.8	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.6	1.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.5	42.4	GO:0005179	hormone activity(GO:0005179)
0.5	2.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.5	2.0	GO:0009055	electron carrier activity(GO:0009055)
0.5	0.5	GO:0001962	alpha-1,3-galactosyltransferase activity(GO:0001962)
0.5	0.5	GO:2001069	glycogen binding(GO:2001069)
0.5	1.4	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.5	3.7	GO:0051018	protein kinase A binding(GO:0051018)
0.5	2.8	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.5	0.9	GO:0004977	melanocortin receptor activity(GO:0004977)
0.5	0.5	GO:0016004	phospholipase activator activity(GO:0016004)
0.4	0.4	GO:0019534	toxin transporter activity(GO:0019534)
0.4	1.2	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.4	0.8	GO:0046332	SMAD binding(GO:0046332)
0.4	0.7	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.4	1.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.4	1.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.3	66.9	GO:0042802	identical protein binding(GO:0042802)
0.3	0.3	GO:0016798	hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.3	2.5	GO:0005550	pheromone binding(GO:0005550)
0.3	0.6	GO:0008502	melatonin receptor activity(GO:0008502)
0.3	1.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3	5.2	GO:0020037	heme binding(GO:0020037)
0.3	0.3	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.3	5.9	GO:0016791	phosphatase activity(GO:0016791)
0.3	36.0	GO:0008289	lipid binding(GO:0008289)
0.3	1.8	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.2	0.5	GO:0022829	wide pore channel activity(GO:0022829)
0.2	0.7	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	22.5	GO:0016503	pheromone receptor activity(GO:0016503)
0.2	3.2	GO:0005186	pheromone activity(GO:0005186)
0.2	2.8	GO:0001594	trace-amine receptor activity(GO:0001594)
0.2	1.1	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.2	4.1	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.2	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	130.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.1	0.3	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	0.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0008308	voltage-gated anion channel activity(GO:0008308)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
30.0	300.3	PID IL5 PATHWAY	IL5-mediated signaling events
29.9	776.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
29.5	826.6	PID IGF1 PATHWAY	IGF1 pathway
25.9	181.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
25.5	357.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
25.3	530.3	PID EPO PATHWAY	EPO signaling pathway
25.1	150.7	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
24.5	171.5	ST STAT3 PATHWAY	STAT3 Pathway
24.2	48.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
23.1	393.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
23.1	508.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
22.9	298.0	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
22.6	789.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
22.3	424.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
22.1	1036.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
21.9	306.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
21.8	1135.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
21.8	304.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
21.6	259.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
21.5	258.5	PID IFNG PATHWAY	IFN-gamma pathway
20.4	183.7	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
20.2	100.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
20.0	638.7	PID RHOA PATHWAY	RhoA signaling pathway
20.0	199.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
19.5	604.0	PID ARF6 PATHWAY	Arf6 signaling events
19.5	19.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
18.4	257.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
17.8	35.7	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
17.5	630.4	PID P53 REGULATION PATHWAY	p53 pathway
17.5	209.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
16.5	281.3	PID MYC PATHWAY	C-MYC pathway
16.5	181.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
16.4	131.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
16.0	528.0	PID MTOR 4PATHWAY	mTOR signaling pathway
15.8	47.4	PID ALK2 PATHWAY	ALK2 signaling events
15.3	106.8	PID S1P S1P1 PATHWAY	S1P1 pathway
15.2	334.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
15.1	393.1	PID ILK PATHWAY	Integrin-linked kinase signaling
15.0	630.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
15.0	45.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
14.8	251.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
14.5	72.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
14.5	144.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
14.1	98.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
13.9	598.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
13.9	166.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
13.8	345.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
13.5	418.7	PID PLK1 PATHWAY	PLK1 signaling events
13.5	94.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
13.3	239.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
13.3	26.6	ST GA12 PATHWAY	G alpha 12 Pathway
13.3	26.5	PID S1P S1P2 PATHWAY	S1P2 pathway
13.1	13.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
13.0	156.5	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
12.9	257.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
12.6	403.8	PID AP1 PATHWAY	AP-1 transcription factor network
12.5	99.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
12.3	355.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
12.1	412.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
11.8	188.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
11.7	222.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
11.7	151.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
11.7	23.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
11.6	23.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
11.5	424.5	PID P73PATHWAY	p73 transcription factor network
11.4	308.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
11.4	34.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
11.2	213.6	PID RAS PATHWAY	Regulation of Ras family activation
11.0	142.7	PID IL1 PATHWAY	IL1-mediated signaling events
10.8	75.5	PID CD40 PATHWAY	CD40/CD40L signaling
10.8	322.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
10.6	74.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
10.6	63.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
10.5	210.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
10.5	272.6	PID E2F PATHWAY	E2F transcription factor network
10.4	229.8	PID RAC1 PATHWAY	RAC1 signaling pathway
10.4	114.4	PID TNF PATHWAY	TNF receptor signaling pathway
10.3	41.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
10.2	172.8	PID ALK1 PATHWAY	ALK1 signaling events
9.9	118.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
9.9	157.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
9.8	167.3	PID LKB1 PATHWAY	LKB1 signaling events
9.8	107.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
9.5	124.0	PID BARD1 PATHWAY	BARD1 signaling events
9.5	9.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
9.5	199.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
9.5	180.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
9.5	227.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
9.3	130.0	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
9.3	37.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
9.2	82.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
9.1	91.5	PID ARF 3PATHWAY	Arf1 pathway
9.0	152.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
8.9	293.3	PID CMYB PATHWAY	C-MYB transcription factor network
8.9	79.9	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
8.9	115.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
8.8	441.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
8.8	79.0	PID ERBB4 PATHWAY	ErbB4 signaling events
8.7	78.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
8.6	266.4	PID NOTCH PATHWAY	Notch signaling pathway
8.5	16.9	PID TRAIL PATHWAY	TRAIL signaling pathway
8.4	75.6	ST GA13 PATHWAY	G alpha 13 Pathway
8.4	167.7	PID AURORA B PATHWAY	Aurora B signaling
8.2	155.3	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
8.1	32.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
7.6	75.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
7.6	60.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
7.3	65.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
7.3	21.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
7.2	107.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
7.1	35.5	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
7.0	28.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
6.9	186.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
6.8	122.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
6.8	196.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
6.7	181.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
6.6	46.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
6.5	52.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
6.5	45.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
6.4	83.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
6.4	95.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
6.4	69.9	PID RB 1PATHWAY	Regulation of retinoblastoma protein
6.3	6.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
6.3	31.6	PID FOXO PATHWAY	FoxO family signaling
6.3	44.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
6.3	31.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
6.2	111.5	PID IL12 2PATHWAY	IL12-mediated signaling events
6.2	18.6	PID SHP2 PATHWAY	SHP2 signaling
6.1	24.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
6.0	119.3	PID FANCONI PATHWAY	Fanconi anemia pathway
5.7	45.7	PID BCR 5PATHWAY	BCR signaling pathway
5.7	22.8	PID IL2 1PATHWAY	IL2-mediated signaling events
5.7	56.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
5.6	101.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
5.5	104.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
5.2	20.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
5.2	5.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
5.2	46.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
5.1	35.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
4.9	9.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
4.8	19.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
4.6	602.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
4.5	72.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
4.3	30.3	PID ATM PATHWAY	ATM pathway
4.2	37.7	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
4.1	28.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
3.8	42.0	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
3.8	34.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
3.7	3.7	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
3.6	21.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
3.6	18.0	PID ATR PATHWAY	ATR signaling pathway
3.5	14.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
3.5	38.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
3.4	10.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
3.4	34.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
3.4	6.8	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
3.3	6.6	PID VEGFR1 PATHWAY	VEGFR1 specific signals
3.2	3.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
3.0	20.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
2.9	43.9	PID IL4 2PATHWAY	IL4-mediated signaling events
2.9	17.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
2.3	4.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
2.2	11.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
2.2	8.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
2.1	398.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.8	3.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.5	14.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
1.5	2.9	ST G ALPHA S PATHWAY	G alpha s Pathway
1.3	11.7	PID BMP PATHWAY	BMP receptor signaling
1.2	9.8	PID IL23 PATHWAY	IL23-mediated signaling events
1.1	43.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
1.0	6.0	PID INSULIN PATHWAY	Insulin Pathway
0.8	2.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.8	4.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.7	133.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.7	5.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.6	3.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	10.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	2.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	0.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
45.5	45.5	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
42.1	210.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
39.2	352.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
31.0	31.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
30.3	454.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
30.2	271.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
28.9	231.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
28.4	539.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
27.1	649.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
25.8	77.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
25.3	227.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
24.8	397.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
24.6	393.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
24.6	196.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
24.1	144.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
23.6	189.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
23.5	682.8	REACTOME G1 PHASE	Genes involved in G1 Phase
23.5	258.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
22.8	91.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
22.7	113.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
22.7	317.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
22.6	271.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
22.0	439.6	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
21.8	349.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
21.6	216.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
21.6	388.9	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
21.1	231.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
21.0	84.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
20.7	373.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
20.5	328.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
20.1	220.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
20.1	120.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
19.9	19.9	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
19.8	158.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
19.8	256.8	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
19.4	174.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
19.1	38.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
18.8	206.5	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
18.6	278.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
18.4	184.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
18.1	126.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
17.7	195.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
17.7	176.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
17.2	103.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
17.1	273.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
16.9	169.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
16.5	396.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
16.4	147.9	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
16.4	310.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
16.2	357.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
15.7	141.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
15.7	1396.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
15.7	31.3	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
15.5	77.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
15.5	540.9	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
15.3	229.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
15.3	152.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
15.2	410.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
15.2	212.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
15.2	91.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
15.2	166.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
15.1	150.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
14.6	72.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
14.5	275.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
14.4	28.8	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
14.3	185.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
14.2	14.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
14.2	14.2	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
14.1	14.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
13.8	481.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
13.6	176.7	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
13.5	338.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
13.5	81.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
13.5	26.9	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
13.4	846.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
13.4	80.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
13.3	239.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
13.2	185.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
13.2	394.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
13.0	78.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
12.9	90.3	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
12.7	278.9	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
12.6	12.6	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
12.4	74.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
12.3	209.6	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
12.3	36.8	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
12.1	12.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
12.1	12.1	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
12.1	133.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
12.1	289.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
12.0	300.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
12.0	216.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
11.9	478.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
11.9	59.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
11.9	427.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
11.9	237.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
11.8	23.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
11.6	174.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
11.6	150.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
11.3	351.5	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
11.1	78.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
11.0	77.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
11.0	76.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
10.9	610.6	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
10.7	10.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
10.7	106.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
10.7	202.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
10.5	52.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
10.5	10.5	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
10.4	10.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
10.3	10.3	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
10.2	285.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
10.1	160.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
10.0	170.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
9.9	228.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
9.8	167.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
9.8	39.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
9.8	88.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
9.6	849.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
9.6	105.9	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
9.6	67.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
9.6	124.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
9.4	28.1	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
9.3	92.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
9.3	176.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
9.2	55.3	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
9.2	18.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
9.1	73.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
9.1	27.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
9.1	90.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
9.0	18.1	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
9.0	360.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
9.0	27.0	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
8.9	142.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
8.9	88.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
8.9	17.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
8.7	130.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
8.6	250.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
8.6	86.0	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
8.6	94.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
8.6	171.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
8.4	67.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
8.4	8.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
8.3	283.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
8.3	124.6	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
8.3	57.8	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
8.2	122.9	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
8.2	302.7	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
8.2	73.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
8.0	96.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
7.9	1212.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
7.9	134.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
7.9	94.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
7.8	125.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
7.8	132.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
7.8	116.7	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
7.8	325.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
7.7	207.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
7.6	68.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
7.6	356.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
7.5	195.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
7.5	104.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
7.4	666.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
7.4	22.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
7.4	58.8	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
7.0	605.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
7.0	147.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
7.0	20.9	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
6.8	75.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
6.7	114.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
6.7	121.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
6.7	80.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
6.7	140.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
6.7	40.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
6.6	171.5	REACTOME DNA REPLICATION	Genes involved in DNA Replication
6.6	78.8	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
6.5	65.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
6.5	136.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
6.5	6.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
6.5	19.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
6.3	107.4	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
6.3	68.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
6.1	171.4	REACTOME TRANSLATION	Genes involved in Translation
6.1	134.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
6.1	72.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
6.0	108.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
6.0	53.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
6.0	17.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
5.9	47.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
5.9	29.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
5.8	58.2	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
5.8	52.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
5.8	75.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
5.8	28.8	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
5.6	163.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
5.5	66.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
5.5	27.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
5.5	71.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
5.5	240.6	REACTOME DNA REPAIR	Genes involved in DNA Repair
5.4	69.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
5.4	37.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
5.3	42.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
5.3	37.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
5.2	5.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
5.2	88.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
5.1	25.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
5.1	81.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
5.1	25.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
5.0	20.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
5.0	24.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
5.0	34.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
5.0	64.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
5.0	138.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
4.9	4.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
4.9	34.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
4.8	9.7	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
4.8	71.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
4.7	23.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
4.7	14.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
4.7	9.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
4.6	274.2	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
4.4	104.7	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
4.3	156.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
4.2	29.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
4.2	37.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
4.2	8.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
4.2	20.8	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
4.0	4.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
4.0	87.2	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
4.0	7.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
3.9	244.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
3.8	3.8	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
3.8	52.6	REACTOME MEIOSIS	Genes involved in Meiosis
3.7	63.0	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
3.7	3.7	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
3.6	14.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
3.5	10.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
3.4	44.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
3.3	13.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
3.3	23.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
3.3	16.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
3.2	35.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
3.2	9.5	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
3.2	15.9	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
3.1	34.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
3.1	6.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
3.0	18.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
3.0	20.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.9	11.8	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
2.8	11.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
2.7	29.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
2.7	24.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
2.6	23.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
2.5	7.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
2.3	18.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
2.1	14.7	REACTOME APOPTOSIS	Genes involved in Apoptosis
2.0	2.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.9	15.3	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
1.8	74.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.7	26.1	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
1.7	99.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
1.6	18.0	REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	Genes involved in Post-translational protein modification
1.6	30.7	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
1.6	1.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
1.6	3.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.5	27.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.4	8.4	REACTOME MEMBRANE TRAFFICKING	Genes involved in Membrane Trafficking
1.4	25.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.2	58.9	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
1.1	5.5	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
1.1	11.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.1	15.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
1.1	4.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
1.0	96.4	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.7	3.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.7	61.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.6	17.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.5	5.4	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.4	5.0	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.3	1.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.3	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1	4.0	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.1	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME DEFENSINS	Genes involved in Defensins

Results for Klf4_Sp3

Z-value: 13.37

Motif logo

Transcription factors associated with Klf4_Sp3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Klf4_Sp3 motif across conditions

Conditions sorted by the z-value of the Klf4_Sp3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf4_Sp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: