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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nfatc4

Z-value: 0.35

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Transcription factors associated with Nfatc4

Gene Symbol	Gene ID	Gene Info
Nfatc4 Ensembl NCBI MGI UniProt	ENSMUSG00000023411.5	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_55824498_55825973	Nfatc4	198	0.874152	0.33	1.5e-02	Click!
chr14_55824260_55824444	Nfatc4	443	0.669096	0.32	1.7e-02	Click!
chr14_55825986_55826137	Nfatc4	260	0.827506	0.29	3.0e-02	Click!
chr14_55822948_55823744	Nfatc4	202	0.870721	0.29	3.3e-02	Click!
chr14_55823772_55824002	Nfatc4	743	0.452656	0.28	4.2e-02	Click!

Activity of the Nfatc4 motif across conditions

Conditions sorted by the z-value of the Nfatc4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_68595404_68595555	0.56	Brinp1	bone morphogenic protein/retinoic acid inducible neural specific 1	233879	0.02
chr4_23173209_23173360	0.53	Gm11884	predicted gene 11884	87500	0.1
chr10_101317018_101317229	0.52	Gm19233	predicted gene, 19233	45502	0.2
chr3_117002231_117002410	0.50	Gm9332	predicted gene 9332	2734	0.23
chr13_111237965_111238337	0.50	3110015C05Rik	RIKEN cDNA 3110015C05 gene	8720	0.21
chr8_55121794_55122373	0.48	Gm8734	predicted gene 8734	40368	0.14
chr2_109694445_109694667	0.48	Bdnf	brain derived neurotrophic factor	87	0.97
chr1_186505235_186505386	0.48	A730004F24Rik	RIKEN cDNA A730004F24 gene	53162	0.15
chr8_55371986_55372445	0.48	Gm20586	predicted gene, 20586	160076	0.04
chr3_70594904_70595055	0.46	Gm37213	predicted gene, 37213	27683	0.24
chr8_55358672_55359287	0.45	Gm20586	predicted gene, 20586	173312	0.03
chr8_55352073_55352667	0.44	Gm20586	predicted gene, 20586	179921	0.03
chr2_22721578_22721729	0.42	Gm13338	predicted gene 13338	8142	0.15
chr1_24226131_24226533	0.42	Col9a1	collagen, type IX, alpha 1	3185	0.33
chr8_55355373_55355937	0.42	Gm20586	predicted gene, 20586	176636	0.03
chr2_97467028_97467474	0.41	Lrrc4c	leucine rich repeat containing 4C	406	0.92
chr8_55115169_55115732	0.40	Gm8734	predicted gene 8734	33735	0.14
chr15_53370344_53370653	0.40	Gm27926	predicted gene, 27926	13421	0.24
chr2_12970544_12970695	0.40	Pter	phosphotriesterase related	7320	0.17
chr3_102366187_102366567	0.40	Gm43242	predicted gene 43242	2785	0.27
chr2_147702775_147702949	0.39	A530006G24Rik	RIKEN cDNA A530006G24 gene	7831	0.23
chr2_66409856_66410177	0.39	Scn1a	sodium channel, voltage-gated, type I, alpha	48	0.9
chr1_98047379_98047565	0.39	B230216N24Rik	RIKEN cDNA B230216N24 gene	282	0.89
chr6_30552193_30552508	0.39	Cpa2	carboxypeptidase A2, pancreatic	447	0.74
chr9_91350886_91351318	0.38	A730094K22Rik	RIKEN cDNA A730094K22 gene	149	0.92
chr16_88681405_88681556	0.38	Gm7667	predicted gene 7667	1248	0.3
chr14_7749794_7749966	0.38	Gm16741	predicted gene, 16741	65	0.97
chr4_119460677_119461253	0.37	Zmynd12	zinc finger, MYND domain containing 12	16245	0.1
chr8_55349027_55349338	0.37	Gm20586	predicted gene, 20586	183109	0.03
chr3_34443838_34444057	0.37	Gm20515	predicted gene 20515	8850	0.18
chr15_6934781_6934981	0.36	Osmr	oncostatin M receptor	59912	0.13
chr3_142411042_142411193	0.34	Pdlim5	PDZ and LIM domain 5	15421	0.23
chr2_63963866_63964056	0.34	Fign	fidgetin	134027	0.06
chr4_27988130_27988413	0.33	Tpm3-rs2	tropomyosin 3, related sequence 2	8634	0.29
chr2_58135097_58135248	0.32	Cytip	cytohesin 1 interacting protein	21625	0.16
chr14_70893868_70894196	0.32	Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	3504	0.28
chr8_55362331_55362582	0.32	Gm20586	predicted gene, 20586	169835	0.03
chr14_122324157_122324364	0.31	Gm25464	predicted gene, 25464	63900	0.09
chr15_54312323_54312474	0.31	Gm5215	predicted gene 5215	33	0.98
chr10_4553737_4553991	0.31	Gm3266	predicted gene 3266	16359	0.17
chr13_25754626_25754869	0.30	Gm11350	predicted gene 11350	73604	0.12
chr3_145645937_145646121	0.30	Ccn1	cellular communication network factor 1	3952	0.21
chr13_78795499_78795660	0.30	Gm48402	predicted gene, 48402	157562	0.04
chr15_27768039_27768190	0.30	Trio	triple functional domain (PTPRF interacting)	19563	0.21
chr2_116894201_116894398	0.29	D330050G23Rik	RIKEN cDNA D330050G23 gene	5853	0.19
chr3_18905759_18906119	0.29	Gm30341	predicted gene, 30341	152862	0.04
chr10_56378893_56379326	0.28	Gja1	gap junction protein, alpha 1	21	0.98
chr12_30129274_30129604	0.28	Tpo	thyroid peroxidase	2460	0.37
chr8_55118866_55119053	0.28	Gm8734	predicted gene 8734	37244	0.14
chrX_110077953_110078105	0.28	Gm4991	predicted gene 4991	167808	0.04
chr5_104416083_104416237	0.27	Spp1	secreted phosphoprotein 1	18958	0.15
chr15_57059947_57060098	0.27	Gm2582	predicted gene 2582	53398	0.17
chr11_102603589_102603785	0.27	Fzd2	frizzled class receptor 2	709	0.5
chr8_55368995_55369146	0.27	Gm20586	predicted gene, 20586	163221	0.04
chr8_55345851_55346060	0.27	Gm20586	predicted gene, 20586	186336	0.03
chr4_85486606_85486757	0.27	Adamtsl1	ADAMTS-like 1	27491	0.25
chr2_13438384_13438535	0.26	Cubn	cubilin (intrinsic factor-cobalamin receptor)	17168	0.25
chr13_91187692_91187893	0.26	Gm17450	predicted gene, 17450	32660	0.16
chr1_168908656_168908844	0.25	Mir6354	microRNA 6354	110339	0.07
chr14_123065129_123065306	0.25	AA536875	expressed sequence AA536875	21935	0.22
chr1_30701244_30701419	0.25	Gm9898	predicted gene 9898	18631	0.22
chrX_150955690_150955875	0.25	Gm8424	predicted gene 8424	29623	0.14
chr15_26895841_26896059	0.25	Fbxl7	F-box and leucine-rich repeat protein 7	370	0.92
chr15_48790820_48790999	0.24	Csmd3	CUB and Sushi multiple domains 3	1024	0.66
chr3_13472076_13472230	0.24	Gm2464	predicted gene 2464	324	0.62
chr15_83848303_83848454	0.24	Mpped1	metallophosphoesterase domain containing 1	12338	0.22
chr6_137699179_137699330	0.24	Strap	serine/threonine kinase receptor associated protein	35824	0.16
chr12_116485218_116485891	0.23	Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	166	0.93
chr10_37139778_37139969	0.23	5930403N24Rik	RIKEN cDNA 5930403N24 gene	41	0.95
chr18_21728656_21729116	0.23	Klhl14	kelch-like 14	74168	0.11
chr2_102094776_102094927	0.23	Gm13920	predicted gene 13920	37264	0.14
chr5_49350667_49350890	0.23	Gm42772	predicted gene 42772	61054	0.09
chr12_100763079_100763279	0.22	Gm25801	predicted gene, 25801	5949	0.16
chr4_90438582_90438776	0.22	Gm12635	predicted gene 12635	14195	0.24
chr1_158163507_158163658	0.22	Brinp2	bone morphogenic protein/retinoic acid inducible neural-specific 2	132882	0.05
chr9_82044648_82044799	0.22	Gm37837	predicted gene, 37837	16143	0.26
chr8_90536167_90536332	0.22	Gm45639	predicted gene 45639	138709	0.04
chr11_76912041_76912192	0.22	Tmigd1	transmembrane and immunoglobulin domain containing 1	7554	0.17
chr1_85870211_85870362	0.21	Itm2c	integral membrane protein 2C	23995	0.12
chr6_125163930_125164575	0.21	Gapdh	glyceraldehyde-3-phosphate dehydrogenase	664	0.41
chr13_89669404_89669574	0.21	Gm16318	predicted gene 16318	6719	0.21
chr13_31792557_31792841	0.21	Gm11379	predicted gene 11379	4840	0.19
chr8_55378818_55378969	0.21	Gm20586	predicted gene, 20586	153398	0.04
chr10_29217677_29217828	0.21	9330159F19Rik	RIKEN cDNA 9330159F19 gene	6047	0.18
chr8_88266957_88267125	0.21	Adcy7	adenylate cyclase 7	5362	0.2
chr15_21407429_21407584	0.20	Gm38234	predicted gene, 38234	227349	0.02
chr5_125149190_125149438	0.20	Ncor2	nuclear receptor co-repressor 2	24414	0.18
chr4_13335515_13335743	0.20	Gm26250	predicted gene, 26250	68579	0.12
chr2_110565079_110565282	0.20	Gm10794	predicted gene 10794	31457	0.18
chr18_7535204_7535355	0.20	Gm18948	predicted gene, 18948	13708	0.23
chr11_29448855_29449034	0.20	Ccdc88a	coiled coil domain containing 88A	7552	0.17
chr5_15043429_15043756	0.20	Gm17019	predicted gene 17019	10594	0.25
chr17_44398035_44398193	0.20	Gm49872	predicted gene, 49872	30211	0.23
chr8_7131824_7132038	0.20	Gm44910	predicted gene 44910	1033	0.65
chr11_72042565_72042858	0.19	Pimreg	PICALM interacting mitotic regulator	187	0.93
chr15_67944519_67944685	0.19	Gm49409	predicted gene, 49409	1798	0.49
chr5_141139181_141139332	0.19	Gm26113	predicted gene, 26113	58825	0.12
chr4_84018889_84019101	0.19	6030471H07Rik	RIKEN cDNA 6030471H07 gene	25884	0.22
chr17_21732990_21733141	0.19	Zfp229	zinc finger protein 229	615	0.62
chr16_77422519_77422863	0.19	9430053O09Rik	RIKEN cDNA 9430053O09 gene	871	0.45
chr15_52161086_52161419	0.19	Gm2387	predicted gene 2387	71944	0.1
chr1_26282913_26283064	0.19	Gm19123	predicted gene, 19123	183248	0.03
chr2_166517600_166517812	0.19	Gm14267	predicted gene 14267	1340	0.5
chr10_13324534_13324685	0.19	Phactr2	phosphatase and actin regulator 2	320	0.93
chr2_104219978_104220129	0.18	Gm22501	predicted gene, 22501	8185	0.16
chr6_4739869_4740257	0.18	Sgce	sarcoglycan, epsilon	144	0.95
chr18_89564398_89564718	0.18	Dok6	docking protein 6	4489	0.24
chr5_131645868_131646247	0.18	Gm43483	predicted gene 43483	3250	0.16
chr3_115619961_115620260	0.18	S1pr1	sphingosine-1-phosphate receptor 1	94962	0.07
chr16_14445264_14445415	0.18	Abcc1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	15669	0.17
chr4_49232759_49232939	0.18	Gm22685	predicted gene, 22685	56449	0.13
chr9_122836785_122837126	0.18	Gm35549	predicted gene, 35549	6931	0.11
chr3_27862930_27863950	0.17	Gm26040	predicted gene, 26040	4673	0.26
chr1_156782534_156782685	0.17	Gm15428	predicted pseudogene 15428	10903	0.15
chr2_97543385_97543550	0.17	Lrrc4c	leucine rich repeat containing 4C	75378	0.11
chr12_112466043_112466390	0.17	A530016L24Rik	RIKEN cDNA A530016L24 gene	23232	0.13
chrX_43430637_43430950	0.17	Tenm1	teneurin transmembrane protein 1	1667	0.41
chr10_27132998_27133149	0.17	Lama2	laminin, alpha 2	76428	0.1
chr1_78745515_78745771	0.17	Gm6159	predicted gene 6159	39216	0.13
chr6_40226222_40226373	0.17	Gm37003	predicted gene, 37003	78	0.97
chr13_113495968_113496190	0.17	4921509O07Rik	RIKEN cDNA 4921509O07 gene	6765	0.16
chr5_14949744_14950125	0.17	Speer4e	spermatogenesis associated glutamate (E)-rich protein 4e	11505	0.19
chr15_89148579_89149159	0.16	Mapk11	mitogen-activated protein kinase 11	625	0.51
chr9_39604057_39604411	0.16	AW551984	expressed sequence AW551984	110	0.93
chr6_127011987_127012359	0.16	Fgf6	fibroblast growth factor 6	3413	0.16
chr10_26711151_26711302	0.16	Gm48893	predicted gene, 48893	15652	0.15
chr6_108235594_108236116	0.16	Itpr1	inositol 1,4,5-trisphosphate receptor 1	17103	0.23
chr16_34228583_34229181	0.15	Kalrn	kalirin, RhoGEF kinase	23433	0.27
chr16_80512891_80513042	0.15	Gm24773	predicted gene, 24773	172259	0.03
chr6_142702177_142702435	0.15	Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	9	0.98
chr10_42477881_42479089	0.15	Afg1l	AFG1 like ATPase	70	0.97
chr7_6753498_6753708	0.15	Gm44863	predicted gene 44863	560	0.61
chr14_75206107_75206258	0.15	Gm15629	predicted gene 15629	6911	0.15
chr19_52048467_52048668	0.15	Gm50330	predicted gene, 50330	128234	0.05
chr16_56920328_56920584	0.15	Lnp1	leukemia NUP98 fusion partner 1	7605	0.16
chr3_145560223_145560406	0.15	Col24a1	collagen, type XXIV, alpha 1	15341	0.19
chr13_47223822_47224099	0.14	Rnf144b	ring finger protein 144B	30135	0.16
chr11_85676422_85676576	0.14	Bcas3	breast carcinoma amplified sequence 3	35795	0.15
chr1_78816664_78817000	0.14	Kcne4	potassium voltage-gated channel, Isk-related subfamily, gene 4	74	0.97
chr13_48228069_48228495	0.14	Gm36346	predicted gene, 36346	8969	0.16
chr3_109025491_109025897	0.14	Fam102b	family with sequence similarity 102, member B	1579	0.31
chr11_110251644_110251914	0.13	Abca6	ATP-binding cassette, sub-family A (ABC1), member 6	3	0.99
chr13_59850542_59850693	0.13	Gm48384	predicted gene, 48384	23025	0.1
chr19_26745483_26745907	0.13	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	486	0.85
chr4_40837444_40837899	0.13	Mir5123	microRNA 5123	12467	0.11
chr2_125355381_125355540	0.13	Gm14003	predicted gene 14003	71482	0.09
chr3_157021687_157021992	0.13	Gm43527	predicted gene 43527	21422	0.21
chr4_43561783_43562397	0.12	Tln1	talin 1	67	0.71
chr4_53011544_53011738	0.12	Nipsnap3b	nipsnap homolog 3B	239	0.91
chr17_49703998_49704149	0.12	Kif6	kinesin family member 6	10037	0.27
chr6_33929843_33930025	0.12	Gm13853	predicted gene 13853	62477	0.12
chr1_162144363_162144537	0.12	Dnm3	dynamin 3	9698	0.2
chr16_31575682_31575833	0.12	Gm34256	predicted gene, 34256	17463	0.16
chr11_98412973_98413218	0.12	Erbb2	erb-b2 receptor tyrosine kinase 2	602	0.51
chr5_97953119_97953468	0.12	Antxr2	anthrax toxin receptor 2	42802	0.14
chr3_69285315_69285466	0.12	Ppm1l	protein phosphatase 1 (formerly 2C)-like	31471	0.14
chr3_8509688_8509990	0.12	Stmn2	stathmin-like 2	253	0.93
chr1_45898190_45898341	0.12	Gm18303	predicted gene, 18303	7358	0.14
chr5_85795902_85796137	0.11	Gm24626	predicted gene, 24626	33608	0.21
chr15_26880673_26880848	0.11	Fbxl7	F-box and leucine-rich repeat protein 7	14758	0.26
chr2_63963398_63963819	0.11	Fign	fidgetin	134380	0.06
chr1_39902764_39903132	0.11	Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	1718	0.42
chr9_55429377_55429605	0.11	Etfa	electron transferring flavoprotein, alpha polypeptide	58022	0.1
chr1_193086803_193086954	0.11	Utp25	UTP25 small subunit processome component	27797	0.12
chr8_110716047_110716632	0.11	Mtss2	MTSS I-BAR domain containing 2	5137	0.18
chrX_130452263_130452432	0.11	Gm14984	predicted gene 14984	50128	0.14
chr4_49213275_49213426	0.11	Gm22685	predicted gene, 22685	75948	0.09
chr1_30719021_30719172	0.10	Gm9898	predicted gene 9898	866	0.65
chr3_148992115_148992398	0.10	Adgrl2	adhesion G protein-coupled receptor L2	1701	0.32
chr7_63924745_63925223	0.10	Klf13	Kruppel-like factor 13	114	0.95
chrX_109845362_109845527	0.10	Gm4991	predicted gene 4991	64777	0.15
chr1_67226374_67226525	0.10	Gm15668	predicted gene 15668	22751	0.2
chr2_177498924_177499075	0.10	Gm14403	predicted gene 14403	684	0.66
chr7_116736401_116736714	0.10	Gm25423	predicted gene, 25423	45072	0.15
chr8_10318195_10318346	0.09	Myo16	myosin XVI	45698	0.18
chrX_133911740_133912091	0.09	Srpx2	sushi-repeat-containing protein, X-linked 2	3467	0.2
chr5_34252384_34252580	0.09	Zfyve28	zinc finger, FYVE domain containing 28	8923	0.12
chr2_6928083_6928276	0.09	Gm10855	predicted gene 10855	6902	0.18
chr6_127150352_127150816	0.09	Ccnd2	cyclin D2	377	0.68
chr7_112289842_112290024	0.09	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	18634	0.26
chr2_85123274_85123495	0.09	Aplnr	apelin receptor	12841	0.12
chr2_72886288_72886551	0.08	Sp3	trans-acting transcription factor 3	54665	0.1
chr6_100707892_100708043	0.08	Gxylt2	glucoside xylosyltransferase 2	3212	0.21
chr12_31654748_31655394	0.08	Cog5	component of oligomeric golgi complex 5	202	0.54
chr1_134858695_134859022	0.08	Ppp1r12b	protein phosphatase 1, regulatory subunit 12B	12438	0.15
chr4_149606130_149606281	0.08	Clstn1	calsyntenin 1	18957	0.12
chr18_62804016_62804176	0.08	2700046A07Rik	RIKEN cDNA 2700046A07 gene	47749	0.14
chr7_100925122_100925295	0.08	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	6899	0.15
chr13_70803034_70803185	0.08	Gm36529	predicted gene, 36529	37342	0.15
chr1_57850016_57850167	0.08	Spats2l	spermatogenesis associated, serine-rich 2-like	4520	0.28
chr3_27710920_27711171	0.08	Fndc3b	fibronectin type III domain containing 3B	194	0.97
chr13_35817740_35817891	0.07	Gm48706	predicted gene, 48706	19065	0.16
chr15_62934546_62934877	0.07	Tsg101-ps	tumor susceptibility gene 101, pseudogene	45937	0.19
chr17_47953060_47953435	0.07	Gm5228	predicted gene 5228	17157	0.13
chr6_114875640_114875809	0.07	Vgll4	vestigial like family member 4	617	0.75
chr1_177729767_177729918	0.07	1700016C15Rik	RIKEN cDNA 1700016C15 gene	28	0.98
chr12_109038321_109038660	0.06	Begain	brain-enriched guanylate kinase-associated	1403	0.37
chr15_76084268_76084515	0.06	Gm48952	predicted gene, 48952	627	0.46
chr9_29514897_29515079	0.06	Gm15521	predicted gene 15521	77522	0.12
chr5_32611305_32611927	0.06	Gm10461	predicted gene 10461	189	0.6

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0007412	axon target recognition(GO:0007412)
0.1	0.3	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.4	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.2	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.0	0.1	GO:0044849	estrous cycle(GO:0044849)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.0	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.5	GO:0030061	mitochondrial crista(GO:0030061)
0.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	GO:0097452	GAIT complex(GO:0097452)
0.3	GO:0005916	fascia adherens(GO:0005916)
0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0043202	lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0071253	connexin binding(GO:0071253)
0.1	0.4	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.4	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport

Results for Nfatc4

Z-value: 0.35

Motif logo

Transcription factors associated with Nfatc4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nfatc4 motif across conditions

Conditions sorted by the z-value of the Nfatc4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: