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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nhlh1

Z-value: 7.75

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Transcription factors associated with Nhlh1

Gene Symbol	Gene ID	Gene Info
Nhlh1 Ensembl NCBI MGI UniProt	ENSMUSG00000051251.3	nescient helix loop helix 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_172048552_172048746	Nhlh1	8924	0.112965	0.90	2.7e-20	Click!
chr1_172047008_172047200	Nhlh1	10469	0.111238	0.88	1.2e-18	Click!
chr1_172049306_172049831	Nhlh1	8005	0.114329	0.87	5.0e-18	Click!
chr1_172053568_172053923	Nhlh1	3828	0.135340	0.87	6.3e-18	Click!
chr1_172057571_172057962	Nhlh1	193	0.899174	0.87	1.1e-17	Click!

Activity of the Nhlh1 motif across conditions

Conditions sorted by the z-value of the Nhlh1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_16561093_16561486	74.31	Fgd4	FYVE, RhoGEF and PH domain containing 4	1070	0.53
chr9_62536098_62537614	41.03	Coro2b	coronin, actin binding protein, 2B	104	0.97
chr10_79613505_79614566	39.85	C2cd4c	C2 calcium-dependent domain containing 4C	10	0.95
chr8_12947304_12948554	33.55	Mcf2l	mcf.2 transforming sequence-like	10	0.49
chr6_124915577_124916697	32.83	Ptms	parathymosin	608	0.37
chr11_4947352_4948069	30.98	Nefh	neurofilament, heavy polypeptide	354	0.82
chr9_112207779_112208199	30.83	Arpp21	cyclic AMP-regulated phosphoprotein, 21	9272	0.2
chr12_72069940_72071249	30.81	Gpr135	G protein-coupled receptor 135	531	0.72
chr13_92425671_92426978	30.61	Ankrd34b	ankyrin repeat domain 34B	17	0.95
chr3_92080488_92081161	29.88	Lor	loricrin	2318	0.17
chr9_8900765_8902148	29.63	Pgr	progesterone receptor	988	0.68
chr3_107479176_107479476	29.56	Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	10621	0.18
chr7_79535477_79536145	29.16	Gm35040	predicted gene, 35040	232	0.85
chr1_3671269_3672324	28.63	Xkr4	X-linked Kx blood group related 4	298	0.89
chr13_83869057_83869227	28.40	2810049E08Rik	RIKEN cDNA 2810049E08 gene	22066	0.18
chr14_118925359_118925599	27.04	Dzip1	DAZ interacting protein 1	19	0.97
chr3_94363621_94364486	26.95	C2cd4d	C2 calcium-dependent domain containing 4D	1550	0.16
chr13_84059070_84059621	26.27	Gm17750	predicted gene, 17750	5427	0.24
chr14_7567758_7569131	25.89	Gm3558	predicted gene 3558	122	0.95
chr3_107479647_107479853	25.87	Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	11045	0.17
chr7_62046082_62046717	25.81	Mir344f	microRNA Mir344f	151	0.94
chr6_91839831_91839982	25.65	Grip2	glutamate receptor interacting protein 2	12656	0.15
chr2_33215438_33216087	25.61	Angptl2	angiopoietin-like 2	307	0.87
chr3_127267961_127268143	25.39	Gm42972	predicted gene 42972	4237	0.16
chr10_79681206_79682337	24.97	Cdc34	cell division cycle 34	424	0.63
chr18_8054510_8054913	24.97	Gm4833	predicted gene 4833	3508	0.33
chr8_45507619_45508001	24.76	Sorbs2	sorbin and SH3 domain containing 2	2	0.98
chr8_40634456_40635069	24.75	Mtmr7	myotubularin related protein 7	3	0.98
chr18_12947284_12947832	24.68	Osbpl1a	oxysterol binding protein-like 1A	5717	0.19
chr3_158561021_158562021	24.48	Lrrc7	leucine rich repeat containing 7	176	0.97
chr6_55676658_55677265	24.42	Neurod6	neurogenic differentiation 6	4302	0.26
chr6_88981517_88981873	24.30	4933427D06Rik	RIKEN cDNA 4933427D06 gene	31012	0.14
chr8_78635037_78635192	24.27	Gm2253	predicted gene 2253	30820	0.18
chr5_34288113_34288876	24.16	Zfyve28	zinc finger, FYVE domain containing 28	45	0.57
chr10_67978939_67980119	24.04	Rtkn2	rhotekin 2	41	0.98
chr14_3208167_3209194	23.93	D830030K20Rik	RIKEN cDNA D830030K20 gene	103	0.95
chr1_38835547_38836894	23.79	Lonrf2	LON peptidase N-terminal domain and ring finger 2	154	0.95
chr4_58943371_58943812	23.55	Zkscan16	zinc finger with KRAB and SCAN domains 16	37	0.97
chr14_5961062_5962084	23.24	Gm3248	predicted gene 3248	172	0.91
chr13_59011549_59011989	22.78	Gm34245	predicted gene, 34245	66527	0.09
chr7_4119309_4120004	22.49	Ttyh1	tweety family member 1	34	0.91
chr2_74426718_74427115	22.45	Lnpk	lunapark, ER junction formation factor	106190	0.05
chr4_47091686_47092366	22.38	Galnt12	polypeptide N-acetylgalactosaminyltransferase 12	103	0.96
chr14_55520440_55521261	22.36	Nrl	neural retina leucine zipper gene	417	0.62
chr4_97418604_97418964	22.20	Gm12696	predicted gene 12696	103548	0.08
chr17_85950005_85950172	22.16	Gm30117	predicted gene, 30117	21509	0.24
chr5_108549866_108550582	22.09	Cplx1	complexin 1	200	0.9
chr6_104492817_104492984	22.00	Cntn6	contactin 6	22	0.99
chr17_27679167_27679824	21.72	Pacsin1	protein kinase C and casein kinase substrate in neurons 1	5686	0.12
chr7_119184201_119185061	21.68	Gpr139	G protein-coupled receptor 139	28	0.98
chr15_73645198_73646275	21.58	Slc45a4	solute carrier family 45, member 4	26	0.6
chr13_116309603_116310279	21.36	Isl1	ISL1 transcription factor, LIM/homeodomain	252	0.94
chr5_37163228_37163473	21.29	Gm1043	predicted gene 1043	501	0.8
chr3_19566788_19567409	21.15	Gm23330	predicted gene, 23330	6845	0.18
chr7_63444022_63445137	21.12	4930554H23Rik	RIKEN cDNA 4930554H23 gene	50	0.67
chr14_70659174_70659883	21.10	Npm2	nucleophosmin/nucleoplasmin 2	284	0.85
chr19_46523220_46524148	21.08	Trim8	tripartite motif-containing 8	9024	0.15
chr8_12873206_12874084	21.08	Mcf2l	mcf.2 transforming sequence-like	161	0.92
chr10_81025274_81025586	21.01	Diras1	DIRAS family, GTP-binding RAS-like 1	21	0.82
chr4_45184399_45185347	21.00	Frmpd1	FERM and PDZ domain containing 1	2	0.98
chr12_111693687_111693960	20.94	Gm36635	predicted gene, 36635	9259	0.09
chr14_123626303_123627238	20.83	Nalcn	sodium leak channel, non-selective	106	0.98
chr2_165563196_165563907	20.72	Eya2	EYA transcriptional coactivator and phosphatase 2	31481	0.13
chr16_65815403_65815951	20.70	Vgll3	vestigial like family member 3	48	0.98
chr2_44696571_44696739	20.64	Gtdc1	glycosyltransferase-like domain containing 1	59782	0.15
chr14_61172444_61173564	20.62	Sacs	sacsin	14	0.98
chr3_66325480_66326023	20.60	Veph1	ventricular zone expressed PH domain-containing 1	28914	0.18
chr19_47014440_47014752	20.50	Ina	internexin neuronal intermediate filament protein, alpha	102	0.87
chr9_45663652_45664379	20.48	Dscaml1	DS cell adhesion molecule like 1	8822	0.19
chr11_32106427_32106633	20.40	Gm12108	predicted gene 12108	5302	0.22
chr5_111220876_111221370	20.33	Ttc28	tetratricopeptide repeat domain 28	4335	0.22
chr7_79572141_79572757	20.28	Gm45168	predicted gene 45168	6619	0.1
chr5_24482511_24483721	20.27	Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	2944	0.12
chr7_37439583_37439757	20.24	Gm44806	predicted gene 44806	27752	0.18
chr4_20777672_20778960	20.07	Nkain3	Na+/K+ transporting ATPase interacting 3	251	0.96
chr14_4018192_4019443	20.06	Gm5796	predicted gene 5796	5124	0.14
chr12_16643779_16644298	20.06	Lpin1	lipin 1	2928	0.23
chr7_84409236_84410328	19.95	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	101	0.96
chr4_134430506_134430992	19.93	1700021N21Rik	RIKEN cDNA 1700021N21 gene	19422	0.1
chr10_52022610_52022833	19.91	Vgll2	vestigial like family member 2	219	0.92
chr4_91374952_91375142	19.91	Elavl2	ELAV like RNA binding protein 1	1260	0.39
chr10_87492542_87493159	19.78	Ascl1	achaete-scute family bHLH transcription factor 1	810	0.64
chr3_93446951_93447770	19.48	Tchh	trichohyalin	5030	0.1
chr16_28445903_28447087	19.44	Fgf12	fibroblast growth factor 12	218	0.97
chr15_71727617_71728041	19.38	Fam135b	family with sequence similarity 135, member B	9	0.98
chr8_31091237_31091775	19.27	Dusp26	dual specificity phosphatase 26 (putative)	144	0.96
chr7_34570196_34571084	19.27	Gm12784	predicted gene 12784	23434	0.15
chr5_15850216_15850406	19.26	Gm42453	predicted gene 42453	19936	0.14
chr10_26695225_26695646	19.19	Gm48893	predicted gene, 48893	139	0.96
chr10_24595329_24596330	19.00	Gm15270	predicted gene 15270	12	0.52
chr5_37162967_37163149	18.95	Gm1043	predicted gene 1043	209	0.94
chr3_8510910_8511440	18.88	Stmn2	stathmin-like 2	1589	0.43
chr2_153071972_153072126	18.82	Ccm2l	cerebral cavernous malformation 2-like	6047	0.15
chr18_5978462_5978815	18.72	Gm34804	predicted gene, 34804	33455	0.17
chr9_92930513_92930898	18.65	Gm28054	predicted gene 28054	34873	0.17
chr2_127521161_127522051	18.60	Kcnip3	Kv channel interacting protein 3, calsenilin	236	0.88
chr12_105899327_105899513	18.59	Gm19554	predicted gene, 19554	421	0.84
chr13_96131942_96132235	18.57	Sv2c	synaptic vesicle glycoprotein 2c	489	0.69
chr5_146713132_146713362	18.52	4930573C15Rik	RIKEN cDNA 4930573C15 gene	6625	0.19
chr8_122284023_122284944	18.47	Zfpm1	zinc finger protein, multitype 1	2342	0.24
chr4_138325465_138326730	18.39	Gm27646	predicted gene, 27646	8	0.64
chr10_43106136_43106524	18.34	Gm29245	predicted gene 29245	47886	0.11
chr4_23982818_23983489	18.33	Gm28448	predicted gene 28448	49199	0.19
chr1_22533152_22534195	18.25	Rims1	regulating synaptic membrane exocytosis 1	21144	0.28
chr7_79525641_79525821	18.24	Mir9-3hg	Mir9-3 host gene	2119	0.16
chr12_73241990_73242324	18.21	Trmt5	TRM5 tRNA methyltransferase 5	40514	0.14
chr4_116016940_116018214	18.20	Faah	fatty acid amide hydrolase	98	0.95
chr9_41889978_41890642	18.11	Gm40513	predicted gene, 40513	294	0.89
chr9_41378019_41378386	18.07	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	1641	0.36
chr4_13480505_13480805	18.04	Gm11826	predicted gene 11826	2537	0.36
chr4_45819207_45819704	17.99	Igfbpl1	insulin-like growth factor binding protein-like 1	3092	0.2
chr1_84695758_84696417	17.97	Dner	delta/notch-like EGF repeat containing	68	0.74
chr13_83721104_83721451	17.97	C130071C03Rik	RIKEN cDNA C130071C03 gene	104	0.95
chr10_62110939_62111480	17.95	Fam241b	family with sequence similarity 241, member B	159	0.95
chr5_102373723_102373883	17.92	Gm42932	predicted gene 42932	42400	0.18
chr10_89872924_89873647	17.86	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B	224	0.95
chr11_29774406_29774599	17.84	Eml6	echinoderm microtubule associated protein like 6	10269	0.17
chr12_111758304_111760062	17.82	Klc1	kinesin light chain 1	170	0.91
chr14_6889264_6890534	17.79	Gm3667	predicted gene 3667	63	0.97
chr4_101508891_101509449	17.77	Dnajc6	DnaJ heat shock protein family (Hsp40) member C6	1140	0.54
chr19_36553934_36555231	17.76	Hectd2	HECT domain E3 ubiquitin protein ligase 2	57	0.98
chr2_151740625_151741514	17.76	Psmf1	proteasome (prosome, macropain) inhibitor subunit 1	224	0.9
chr14_12338097_12338549	17.74	Gm24578	predicted gene, 24578	4419	0.14
chr9_61530285_61530668	17.53	Gm34424	predicted gene, 34424	2939	0.32
chr3_109782232_109782939	17.50	Ntng1	netrin G1	50674	0.16
chr9_53705535_53706804	17.48	Rab39	RAB39, member RAS oncogene family	63	0.96
chr12_70680124_70680305	17.48	Gm32369	predicted gene, 32369	1636	0.31
chr1_136142237_136142876	17.48	Kif21b	kinesin family member 21B	11102	0.11
chr2_180854741_180854913	17.47	Gm14339	predicted gene 14339	7175	0.11
chr7_12779870_12780809	17.47	Zscan18	zinc finger and SCAN domain containing 18	315	0.58
chr7_99267195_99268129	17.45	Map6	microtubule-associated protein 6	173	0.76
chr5_30712274_30713396	17.36	Dpysl5	dihydropyrimidinase-like 5	934	0.49
chr16_16561514_16561689	17.30	Fgd4	FYVE, RhoGEF and PH domain containing 4	1382	0.44
chrX_143543266_143543620	17.29	Pak3	p21 (RAC1) activated kinase 3	24745	0.25
chr9_124439906_124440949	17.24	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	441	0.79
chr3_105585758_105586171	17.24	Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	83041	0.07
chr2_28446566_28447382	17.16	Ppp1r26	protein phosphatase 1, regulatory subunit 26	108	0.95
chr4_148327377_148327851	17.12	Gm13206	predicted gene 13206	20761	0.14
chr1_92910895_92912569	17.08	Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	523	0.52
chr1_88924043_88924538	17.03	Gm4753	predicted gene 4753	8029	0.23
chr19_61225302_61226760	17.00	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	541	0.67
chr4_120277239_120277533	16.95	Foxo6	forkhead box O6	9963	0.21
chr4_9859459_9860339	16.83	Gdf6	growth differentiation factor 6	15527	0.22
chr3_92081181_92081919	16.79	Lor	loricrin	1592	0.24
chr17_48999548_48999943	16.77	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	67366	0.11
chr8_4210272_4211025	16.77	4932443L11Rik	RIKEN cDNA 4932443L11 gene	3766	0.1
chr18_36017856_36019112	16.71	Nrg2	neuregulin 2	13457	0.16
chr7_75329116_75329290	16.70	Sv2b	synaptic vesicle glycoprotein 2 b	19941	0.17
chr6_82939285_82939948	16.70	Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	71	0.94
chr11_54303609_54304215	16.66	Acsl6	acyl-CoA synthetase long-chain family member 6	93	0.96
chr9_75610973_75611679	16.63	Tmod2	tropomodulin 2	1	0.97
chr13_10360181_10360716	16.62	Chrm3	cholinergic receptor, muscarinic 3, cardiac	115	0.97
chrX_133688279_133688924	16.58	Pcdh19	protocadherin 19	386	0.92
chr17_68841123_68841681	16.57	Gm49949	predicted gene, 49949	2623	0.24
chr4_21930986_21931430	16.57	Faxc	failed axon connections homolog	121	0.97
chr1_93227325_93227654	16.45	Sned1	sushi, nidogen and EGF-like domains 1	8352	0.14
chr8_36142092_36142588	16.44	Gm38414	predicted gene, 38414	13670	0.15
chr4_91371091_91372260	16.43	Elavl2	ELAV like RNA binding protein 1	281	0.88
chr16_45724762_45725141	16.39	Tagln3	transgelin 3	343	0.83
chr17_27203606_27204996	16.36	Lemd2	LEM domain containing 2	168	0.9
chr2_25319011_25319403	16.35	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	20	0.93
chr14_4334095_4335404	16.29	2610042L04Rik	RIKEN cDNA 2610042L04 gene	14	0.97
chr18_83523941_83524284	16.29	Gm50416	predicted gene, 50416	1192	0.46
chr13_112100671_112101178	16.25	Gm31104	predicted gene, 31104	37192	0.15
chr17_9167143_9167467	16.21	6530411M01Rik	RIKEN cDNA 6530411M01 gene	531	0.8
chr5_149489128_149489325	16.20	Gm2566	predicted gene 2566	13826	0.12
chr15_74672233_74673425	16.19	Arc	activity regulated cytoskeletal-associated protein	259	0.85
chr7_109493646_109494020	16.15	Trim66	tripartite motif-containing 66	95	0.95
chr10_42477881_42479089	16.15	Afg1l	AFG1 like ATPase	70	0.97
chr9_83805509_83806110	16.13	Elovl4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4	443	0.84
chr3_8830969_8831121	16.10	Gm15467	predicted gene 15467	50154	0.11
chr1_42703489_42704501	16.06	Pantr2	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2	4057	0.16
chr18_11892775_11892946	16.04	Gm49968	predicted gene, 49968	20271	0.17
chr4_155345224_155345890	16.02	Prkcz	protein kinase C, zeta	175	0.92
chr14_124192585_124192818	16.02	Fgf14	fibroblast growth factor 14	201	0.97
chrX_103533421_103533606	15.99	Gm9157	predicted gene 9157	4030	0.09
chr16_30308519_30309364	15.98	Gp5	glycoprotein 5 (platelet)	1838	0.29
chr18_25590199_25590989	15.87	Gm3227	predicted gene 3227	6896	0.29
chr4_75561854_75562168	15.86	Gm11259	predicted gene 11259	181251	0.03
chr14_54912471_54913268	15.86	Slc22a17	solute carrier family 22 (organic cation transporter), member 17	21	0.93
chr8_71628994_71630252	15.81	Mir6769b	microRNA 6769b	1483	0.21
chr15_75566838_75567525	15.73	Ly6h	lymphocyte antigen 6 complex, locus H	35	0.96
chr6_5380590_5380838	15.69	Asb4	ankyrin repeat and SOCS box-containing 4	2672	0.34
chr1_14755119_14756069	15.67	Gm9947	predicted gene 9947	140	0.64
chr6_138420273_138420927	15.62	Lmo3	LIM domain only 3	852	0.59
chr16_9281007_9281201	15.56	Gm49451	predicted gene, 49451	122334	0.06
chr9_103146716_103147058	15.55	Gm37166	predicted gene, 37166	26519	0.13
chr3_131054299_131054567	15.52	A430072C10Rik	RIKEN cDNA A430072C10 gene	28063	0.15
chr16_41510930_41511158	15.51	Lsamp	limbic system-associated membrane protein	21814	0.26
chr14_6287027_6287952	15.50	Gm3411	predicted gene 3411	239	0.89
chr16_38924994_38925169	15.49	Gm22500	predicted gene, 22500	2128	0.33
chr1_42491113_42491583	15.45	Gm37047	predicted gene, 37047	465	0.88
chr7_48137248_48137604	15.44	Gm28665	predicted gene 28665	19985	0.11
chr4_128715231_128715603	15.41	Phc2	polyhomeotic 2	5253	0.21
chr5_71976591_71976789	15.40	Gm15617	predicted gene 15617	56798	0.14
chrX_142390195_142391160	15.39	Acsl4	acyl-CoA synthetase long-chain family member 4	142	0.95
chr16_37584223_37584651	15.38	Hgd	homogentisate 1, 2-dioxygenase	4155	0.17
chr9_116807725_116808119	15.34	Rbms3	RNA binding motif, single stranded interacting protein	14884	0.3
chr1_154726696_154727096	15.34	Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	540	0.87
chr2_181134637_181135435	15.31	Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	91	0.95

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nhlh1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.6	52.7	GO:0033693	neurofilament bundle assembly(GO:0033693)
16.5	49.5	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
14.0	42.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
10.9	43.7	GO:0030035	microspike assembly(GO:0030035)
10.9	32.6	GO:0021586	pons maturation(GO:0021586)
10.0	20.1	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
9.7	29.2	GO:0003358	noradrenergic neuron development(GO:0003358)
9.1	72.7	GO:0046069	cGMP catabolic process(GO:0046069)
8.4	25.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
8.3	24.9	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
7.8	31.2	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
7.7	30.6	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
7.6	22.8	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
7.6	22.7	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
7.5	22.6	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
7.5	7.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
7.5	22.4	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
7.1	28.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
7.1	42.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
7.1	35.3	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
7.0	28.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
6.9	6.9	GO:0061205	paramesonephric duct development(GO:0061205)
6.9	20.7	GO:0032289	central nervous system myelin formation(GO:0032289)
6.7	46.8	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
6.4	12.9	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
6.4	19.2	GO:0061642	chemoattraction of axon(GO:0061642)
6.3	25.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
6.3	25.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
6.1	6.1	GO:1904861	excitatory synapse assembly(GO:1904861)
6.1	18.3	GO:0030070	insulin processing(GO:0030070)
6.1	30.3	GO:0021631	optic nerve morphogenesis(GO:0021631)
6.0	12.0	GO:2000821	regulation of grooming behavior(GO:2000821)
5.9	5.9	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
5.9	17.8	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
5.9	29.5	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
5.8	5.8	GO:0021550	medulla oblongata development(GO:0021550)
5.8	17.4	GO:0072221	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
5.7	11.4	GO:0002175	protein localization to paranode region of axon(GO:0002175) protein localization to axon(GO:0099612)
5.6	11.3	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
5.6	22.5	GO:0007158	neuron cell-cell adhesion(GO:0007158)
5.6	16.9	GO:0070634	transepithelial ammonium transport(GO:0070634)
5.6	11.2	GO:0097477	lateral motor column neuron migration(GO:0097477)
5.6	16.8	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
5.6	11.2	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
5.6	22.3	GO:0007386	compartment pattern specification(GO:0007386)
5.4	16.3	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
5.4	10.9	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
5.4	113.9	GO:0035418	protein localization to synapse(GO:0035418)
5.4	32.3	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
5.3	15.9	GO:0003219	cardiac right ventricle formation(GO:0003219)
5.3	5.3	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
5.2	41.9	GO:0098828	modulation of inhibitory postsynaptic potential(GO:0098828)
5.2	15.7	GO:0060178	regulation of exocyst localization(GO:0060178)
5.2	103.2	GO:0008038	neuron recognition(GO:0008038)
5.1	15.4	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
5.1	15.3	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
5.0	15.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
5.0	5.0	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
4.9	14.7	GO:0097105	presynaptic membrane assembly(GO:0097105)
4.9	102.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
4.8	19.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
4.7	4.7	GO:0050923	regulation of negative chemotaxis(GO:0050923)
4.7	9.4	GO:0038128	ERBB2 signaling pathway(GO:0038128)
4.7	18.7	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
4.6	9.3	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
4.6	13.9	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
4.6	41.7	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715)
4.6	13.7	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
4.5	18.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
4.5	40.5	GO:0050957	equilibrioception(GO:0050957)
4.5	17.9	GO:0042473	outer ear morphogenesis(GO:0042473)
4.5	13.4	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
4.4	8.8	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
4.4	8.7	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
4.4	13.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
4.3	13.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
4.3	51.9	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
4.3	17.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
4.3	12.8	GO:0030327	prenylated protein catabolic process(GO:0030327)
4.2	12.7	GO:0001927	exocyst assembly(GO:0001927)
4.2	12.7	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
4.2	12.7	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
4.2	8.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
4.1	8.3	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
4.1	24.7	GO:0048752	semicircular canal morphogenesis(GO:0048752)
4.1	12.3	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
4.1	16.4	GO:0002051	osteoblast fate commitment(GO:0002051)
4.1	12.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
4.1	28.7	GO:0060513	prostatic bud formation(GO:0060513)
4.1	8.2	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
4.1	16.3	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
4.1	8.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
4.0	36.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
4.0	12.1	GO:0097091	synaptic vesicle clustering(GO:0097091)
4.0	27.9	GO:0071625	vocalization behavior(GO:0071625)
4.0	8.0	GO:0014028	notochord formation(GO:0014028)
4.0	7.9	GO:0046959	habituation(GO:0046959)
3.9	11.8	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
3.9	15.7	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
3.9	11.7	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
3.9	11.6	GO:0072092	ureteric bud invasion(GO:0072092)
3.9	38.6	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
3.9	3.9	GO:0006517	protein deglycosylation(GO:0006517)
3.8	3.8	GO:0014819	regulation of twitch skeletal muscle contraction(GO:0014724) regulation of skeletal muscle contraction(GO:0014819)
3.8	30.6	GO:0021859	pyramidal neuron differentiation(GO:0021859)
3.8	26.6	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
3.8	60.5	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
3.8	11.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
3.8	37.6	GO:0022038	corpus callosum development(GO:0022038)
3.7	11.2	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
3.7	22.0	GO:0086015	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
3.7	7.3	GO:0060024	rhythmic synaptic transmission(GO:0060024)
3.6	14.5	GO:0014826	vein smooth muscle contraction(GO:0014826)
3.6	7.1	GO:2001025	positive regulation of response to drug(GO:2001025)
3.5	21.3	GO:0048840	otolith development(GO:0048840)
3.5	3.5	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.5	14.1	GO:0060278	regulation of ovulation(GO:0060278)
3.5	10.5	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
3.5	3.5	GO:0060129	corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
3.5	10.4	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
3.4	6.9	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
3.4	17.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
3.4	51.3	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
3.4	6.8	GO:0061743	motor learning(GO:0061743)
3.4	6.8	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
3.4	6.8	GO:0007621	negative regulation of female receptivity(GO:0007621)
3.4	3.4	GO:0009629	response to gravity(GO:0009629)
3.4	6.7	GO:0032025	response to cobalt ion(GO:0032025)
3.3	13.4	GO:0007258	JUN phosphorylation(GO:0007258)
3.3	169.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
3.3	20.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
3.3	6.6	GO:0097374	sensory neuron axon guidance(GO:0097374)
3.3	3.3	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
3.3	3.3	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
3.3	13.0	GO:1990035	calcium ion import into cell(GO:1990035)
3.3	9.8	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
3.2	16.2	GO:0060292	long term synaptic depression(GO:0060292)
3.2	9.7	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
3.2	12.8	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
3.2	6.4	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
3.2	12.7	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
3.2	22.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
3.2	9.5	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
3.1	12.5	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
3.1	6.1	GO:0071679	commissural neuron axon guidance(GO:0071679)
3.1	15.3	GO:0071420	cellular response to histamine(GO:0071420)
3.0	12.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
3.0	18.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
3.0	3.0	GO:2001023	regulation of response to drug(GO:2001023)
3.0	9.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
3.0	9.0	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
3.0	35.4	GO:0016486	peptide hormone processing(GO:0016486)
2.9	14.7	GO:0090383	phagosome acidification(GO:0090383)
2.9	8.8	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
2.9	2.9	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.9	8.7	GO:1901656	glycoside transport(GO:1901656)
2.9	11.5	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
2.9	8.6	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
2.8	14.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.8	8.5	GO:0072318	clathrin coat disassembly(GO:0072318)
2.8	11.2	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
2.8	5.6	GO:0045759	negative regulation of action potential(GO:0045759)
2.8	11.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
2.8	11.0	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
2.7	8.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
2.7	11.0	GO:0023041	neuronal signal transduction(GO:0023041)
2.7	8.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
2.7	5.4	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
2.7	10.8	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
2.7	21.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
2.7	8.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
2.7	5.4	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
2.7	10.7	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
2.7	8.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
2.7	2.7	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
2.6	18.5	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.6	2.6	GO:0072191	ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
2.6	10.5	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
2.6	2.6	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
2.6	41.0	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
2.6	2.6	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
2.6	12.8	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
2.6	35.7	GO:0001964	startle response(GO:0001964)
2.5	7.6	GO:0033566	gamma-tubulin complex localization(GO:0033566)
2.5	10.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
2.5	12.5	GO:0000160	phosphorelay signal transduction system(GO:0000160)
2.5	5.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
2.5	7.4	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
2.5	7.4	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
2.5	4.9	GO:0089700	protein kinase D signaling(GO:0089700)
2.4	7.3	GO:0071895	odontoblast differentiation(GO:0071895)
2.4	41.3	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
2.4	4.8	GO:0072697	protein localization to cell cortex(GO:0072697)
2.4	4.8	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
2.4	4.8	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
2.4	2.4	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
2.4	4.7	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
2.4	23.7	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.4	9.5	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
2.4	2.4	GO:2000680	regulation of rubidium ion transport(GO:2000680)
2.4	16.5	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
2.4	25.9	GO:0060081	membrane hyperpolarization(GO:0060081)
2.3	4.7	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
2.3	9.4	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
2.3	7.0	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
2.3	4.7	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
2.3	4.7	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
2.3	9.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
2.3	6.9	GO:0045218	zonula adherens maintenance(GO:0045218)
2.3	6.9	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
2.3	13.8	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
2.3	27.6	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
2.3	2.3	GO:0060982	coronary artery morphogenesis(GO:0060982)
2.3	2.3	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
2.3	18.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
2.3	6.8	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
2.3	6.8	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
2.2	4.5	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.2	11.2	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
2.2	6.7	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
2.2	6.7	GO:0021698	cerebellar cortex structural organization(GO:0021698)
2.2	24.5	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
2.2	6.7	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
2.2	4.4	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
2.2	140.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.2	4.3	GO:0060221	retinal rod cell differentiation(GO:0060221)
2.2	8.6	GO:0035902	response to immobilization stress(GO:0035902)
2.1	6.4	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.1	6.4	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
2.1	19.0	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
2.1	6.3	GO:0001922	B-1 B cell homeostasis(GO:0001922)
2.1	4.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
2.1	4.2	GO:0001661	conditioned taste aversion(GO:0001661)
2.1	6.2	GO:0071492	cellular response to UV-A(GO:0071492)
2.1	14.5	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
2.1	2.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
2.1	2.1	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
2.0	4.1	GO:1903416	response to glycoside(GO:1903416)
2.0	4.1	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
2.0	10.1	GO:1904424	regulation of GTP binding(GO:1904424)
2.0	6.1	GO:1902534	single-organism membrane invagination(GO:1902534)
2.0	12.1	GO:2000035	regulation of stem cell division(GO:2000035)
2.0	2.0	GO:0035993	deltoid tuberosity development(GO:0035993)
2.0	11.9	GO:0030432	peristalsis(GO:0030432)
2.0	4.0	GO:0090427	activation of meiosis(GO:0090427)
2.0	5.9	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
2.0	3.9	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
2.0	5.9	GO:0060179	male mating behavior(GO:0060179)
2.0	3.9	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.0	2.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
2.0	5.9	GO:0001712	ectodermal cell fate commitment(GO:0001712)
1.9	11.6	GO:0015884	folic acid transport(GO:0015884)
1.9	17.3	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
1.9	9.6	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
1.9	7.6	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.9	11.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.9	13.3	GO:0034331	cell junction maintenance(GO:0034331)
1.9	9.4	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
1.9	5.7	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
1.9	9.4	GO:0060484	lung-associated mesenchyme development(GO:0060484)
1.9	7.5	GO:1903011	negative regulation of bone development(GO:1903011)
1.9	11.2	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
1.9	14.9	GO:0046339	diacylglycerol metabolic process(GO:0046339)
1.9	5.6	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.9	3.7	GO:0030382	sperm mitochondrion organization(GO:0030382)
1.8	1.8	GO:0021524	visceral motor neuron differentiation(GO:0021524)
1.8	9.2	GO:0035641	locomotory exploration behavior(GO:0035641)
1.8	23.7	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.8	12.7	GO:0090103	cochlea morphogenesis(GO:0090103)
1.8	9.1	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
1.8	16.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.8	1.8	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
1.8	12.3	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
1.7	3.5	GO:0014738	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.7	5.2	GO:0042637	catagen(GO:0042637)
1.7	5.2	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
1.7	1.7	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
1.7	3.4	GO:0014824	artery smooth muscle contraction(GO:0014824)
1.7	25.8	GO:0030322	stabilization of membrane potential(GO:0030322)
1.7	1.7	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.7	5.1	GO:0001806	type IV hypersensitivity(GO:0001806)
1.7	16.9	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.7	5.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.7	5.0	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
1.7	3.4	GO:0090385	phagosome-lysosome fusion(GO:0090385)
1.7	5.0	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7	8.4	GO:0072178	nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
1.7	1.7	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.7	6.7	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
1.7	3.3	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.7	36.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
1.7	5.0	GO:0021871	forebrain regionalization(GO:0021871)
1.6	4.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
1.6	4.9	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
1.6	4.9	GO:0060004	reflex(GO:0060004)
1.6	14.7	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
1.6	4.9	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
1.6	16.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.6	4.9	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
1.6	9.7	GO:0048149	behavioral response to ethanol(GO:0048149)
1.6	25.8	GO:0019228	neuronal action potential(GO:0019228)
1.6	3.2	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
1.6	6.4	GO:0002035	brain renin-angiotensin system(GO:0002035)
1.6	1.6	GO:0036119	response to platelet-derived growth factor(GO:0036119)
1.6	22.2	GO:0003416	endochondral bone growth(GO:0003416)
1.6	11.1	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
1.6	3.1	GO:0032808	lacrimal gland development(GO:0032808)
1.6	6.3	GO:2000520	regulation of immunological synapse formation(GO:2000520)
1.6	1.6	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
1.6	10.9	GO:0016082	synaptic vesicle priming(GO:0016082)
1.6	4.7	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
1.5	9.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.5	9.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
1.5	6.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
1.5	6.1	GO:0021542	dentate gyrus development(GO:0021542)
1.5	3.0	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.5	6.0	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
1.5	6.0	GO:1903779	regulation of cardiac conduction(GO:1903779)
1.5	7.5	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.5	4.5	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
1.5	4.5	GO:1902774	late endosome to lysosome transport(GO:1902774)
1.5	3.0	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.5	4.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.4	2.9	GO:0043490	malate-aspartate shuttle(GO:0043490)
1.4	2.9	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.4	5.7	GO:0070314	G1 to G0 transition(GO:0070314)
1.4	5.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
1.4	5.6	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
1.4	19.6	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.4	1.4	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
1.4	2.8	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.4	4.2	GO:0032074	negative regulation of nuclease activity(GO:0032074)
1.4	2.8	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.4	4.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.4	5.5	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.4	9.6	GO:0060736	prostate gland growth(GO:0060736)
1.4	1.4	GO:2000381	negative regulation of mesoderm development(GO:2000381)
1.4	1.4	GO:0090135	actin filament branching(GO:0090135)
1.4	9.5	GO:0060914	heart formation(GO:0060914)
1.4	28.4	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
1.3	4.0	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
1.3	16.2	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
1.3	16.1	GO:0048268	clathrin coat assembly(GO:0048268)
1.3	4.0	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
1.3	5.3	GO:0008090	retrograde axonal transport(GO:0008090)
1.3	2.7	GO:0060973	cell migration involved in heart development(GO:0060973)
1.3	4.0	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
1.3	6.6	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
1.3	1.3	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.3	5.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
1.3	2.6	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
1.3	2.6	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
1.3	2.6	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
1.3	2.6	GO:1900449	regulation of neurotransmitter receptor activity(GO:0099601) regulation of glutamate receptor signaling pathway(GO:1900449)
1.3	2.6	GO:0032672	regulation of interleukin-3 production(GO:0032672)
1.3	1.3	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
1.3	17.8	GO:0007416	synapse assembly(GO:0007416)
1.3	3.8	GO:0001975	response to amphetamine(GO:0001975)
1.3	3.8	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
1.3	2.5	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
1.3	3.8	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
1.3	12.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.3	5.0	GO:0060013	righting reflex(GO:0060013)
1.3	16.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
1.3	20.0	GO:0071475	cellular response to salt stress(GO:0071472) cellular hyperosmotic salinity response(GO:0071475)
1.2	7.5	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
1.2	3.7	GO:0050955	thermoception(GO:0050955)
1.2	14.9	GO:0021954	central nervous system neuron development(GO:0021954)
1.2	6.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.2	8.7	GO:0010544	negative regulation of platelet activation(GO:0010544)
1.2	158.6	GO:0006813	potassium ion transport(GO:0006813)
1.2	7.4	GO:0007042	lysosomal lumen acidification(GO:0007042)
1.2	2.5	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
1.2	7.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.2	7.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
1.2	3.6	GO:0050805	negative regulation of synaptic transmission(GO:0050805)
1.2	8.4	GO:0060384	innervation(GO:0060384)
1.2	2.4	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
1.2	1.2	GO:2000618	regulation of histone H4-K16 acetylation(GO:2000618)
1.2	2.4	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
1.2	12.9	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
1.2	4.7	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
1.2	4.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
1.2	4.6	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.2	4.6	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.2	3.5	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
1.2	1.2	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
1.1	3.4	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
1.1	1.1	GO:0060594	mammary gland specification(GO:0060594)
1.1	3.4	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
1.1	9.1	GO:0046621	negative regulation of organ growth(GO:0046621)
1.1	2.3	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
1.1	5.7	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
1.1	2.3	GO:0001834	trophectodermal cell proliferation(GO:0001834)
1.1	3.4	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
1.1	2.2	GO:0014042	positive regulation of neuron maturation(GO:0014042)
1.1	6.7	GO:0060997	dendritic spine morphogenesis(GO:0060997)
1.1	1.1	GO:0071500	cellular response to nitrosative stress(GO:0071500)
1.1	2.2	GO:0030222	eosinophil differentiation(GO:0030222)
1.1	2.2	GO:0061055	myotome development(GO:0061055)
1.1	2.2	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
1.1	4.4	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
1.1	4.4	GO:0051639	actin filament network formation(GO:0051639)
1.1	3.3	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1	9.8	GO:0006983	ER overload response(GO:0006983)
1.1	5.4	GO:0015808	L-alanine transport(GO:0015808)
1.1	4.3	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.1	2.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
1.1	3.2	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
1.1	4.2	GO:0060074	synapse maturation(GO:0060074)
1.1	6.4	GO:0021854	hypothalamus development(GO:0021854)
1.1	3.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
1.0	2.1	GO:0021670	lateral ventricle development(GO:0021670)
1.0	3.1	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
1.0	3.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.0	8.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
1.0	6.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.0	9.3	GO:0035428	hexose transmembrane transport(GO:0035428)
1.0	1.0	GO:0070305	response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
1.0	2.0	GO:0071600	otic vesicle morphogenesis(GO:0071600)
1.0	1.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
1.0	20.2	GO:0048305	immunoglobulin secretion(GO:0048305)
1.0	1.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
1.0	3.0	GO:0006551	leucine metabolic process(GO:0006551)
1.0	9.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
1.0	1.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
1.0	4.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.0	6.9	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
1.0	1.0	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
1.0	1.0	GO:0021764	amygdala development(GO:0021764)
1.0	2.9	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
1.0	3.9	GO:0071803	positive regulation of podosome assembly(GO:0071803)
1.0	6.8	GO:1902018	negative regulation of cilium assembly(GO:1902018)
1.0	1.9	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
1.0	1.9	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
1.0	3.8	GO:0035627	ceramide transport(GO:0035627)
1.0	3.8	GO:0016576	histone dephosphorylation(GO:0016576)
1.0	1.9	GO:0046952	ketone body catabolic process(GO:0046952)
1.0	5.7	GO:0051231	spindle elongation(GO:0051231)
0.9	0.9	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.9	7.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.9	4.7	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.9	2.8	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.9	4.7	GO:0031652	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.9	5.6	GO:1901678	iron coordination entity transport(GO:1901678)
0.9	2.8	GO:0002930	trabecular meshwork development(GO:0002930)
0.9	2.8	GO:0007638	mechanosensory behavior(GO:0007638)
0.9	4.7	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.9	1.9	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.9	1.8	GO:0042940	D-amino acid transport(GO:0042940)
0.9	4.6	GO:0035881	amacrine cell differentiation(GO:0035881)
0.9	11.9	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.9	2.7	GO:0006597	spermine biosynthetic process(GO:0006597)
0.9	4.5	GO:0034398	telomere tethering at nuclear periphery(GO:0034398)
0.9	5.4	GO:0030497	fatty acid elongation(GO:0030497)
0.9	4.5	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.9	58.5	GO:0001764	neuron migration(GO:0001764)
0.9	1.8	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.9	2.6	GO:0060068	vagina development(GO:0060068)
0.9	1.8	GO:0070141	response to UV-A(GO:0070141)
0.9	6.1	GO:0006108	malate metabolic process(GO:0006108)
0.9	3.5	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.9	1.7	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.9	11.2	GO:0006415	translational termination(GO:0006415)
0.9	4.3	GO:0021681	cerebellar granular layer development(GO:0021681)
0.9	0.9	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.9	3.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.9	0.9	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.9	0.9	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.9	1.7	GO:2000191	regulation of fatty acid transport(GO:2000191)
0.8	2.5	GO:0048254	snoRNA localization(GO:0048254)
0.8	2.5	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.8	1.7	GO:0070668	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.8	1.7	GO:0060437	lung growth(GO:0060437)
0.8	3.4	GO:0035822	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.8	1.7	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.8	0.8	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.8	2.5	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.8	1.7	GO:0042360	vitamin E metabolic process(GO:0042360)
0.8	4.2	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.8	9.1	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.8	14.1	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.8	0.8	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.8	2.5	GO:0032570	response to progesterone(GO:0032570)
0.8	3.3	GO:0030091	protein repair(GO:0030091)
0.8	4.9	GO:0006020	inositol metabolic process(GO:0006020)
0.8	1.6	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.8	2.4	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.8	4.0	GO:0048539	bone marrow development(GO:0048539)
0.8	8.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.8	5.6	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.8	0.8	GO:0035995	detection of muscle stretch(GO:0035995)
0.8	3.9	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.8	1.6	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.8	2.3	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.8	1.6	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.8	2.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.8	2.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.8	0.8	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.8	0.8	GO:0010996	response to auditory stimulus(GO:0010996)
0.8	6.1	GO:0019226	transmission of nerve impulse(GO:0019226)
0.8	2.3	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.8	0.8	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
0.8	5.4	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.8	2.3	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.8	0.8	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.8	3.8	GO:0006642	triglyceride mobilization(GO:0006642)
0.7	1.5	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.7	1.5	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.7	1.5	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.7	22.9	GO:0046847	filopodium assembly(GO:0046847)
0.7	1.5	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.7	3.0	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.7	3.7	GO:0099515	actin filament-based transport(GO:0099515)
0.7	3.7	GO:0033227	dsRNA transport(GO:0033227)
0.7	2.2	GO:0006553	lysine metabolic process(GO:0006553)
0.7	2.2	GO:0001504	neurotransmitter uptake(GO:0001504)
0.7	2.9	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.7	2.2	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.7	2.2	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7	6.5	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.7	2.1	GO:2000465	regulation of glycogen (starch) synthase activity(GO:2000465)
0.7	2.1	GO:0035810	positive regulation of urine volume(GO:0035810)
0.7	2.8	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.7	1.4	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.7	9.0	GO:0061462	protein localization to lysosome(GO:0061462)
0.7	3.4	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.7	3.4	GO:0034453	microtubule anchoring(GO:0034453)
0.7	2.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.7	17.8	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.7	0.7	GO:0060166	olfactory pit development(GO:0060166)
0.7	2.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.7	3.4	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.7	3.4	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.7	0.7	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.7	2.0	GO:0051182	coenzyme transport(GO:0051182)
0.7	6.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.7	3.3	GO:0051503	adenine nucleotide transport(GO:0051503)
0.7	0.7	GO:2000391	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.7	2.7	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.7	3.3	GO:0042428	serotonin metabolic process(GO:0042428)
0.7	2.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.7	1.3	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.7	5.3	GO:0048745	smooth muscle tissue development(GO:0048745)
0.7	0.7	GO:0007412	axon target recognition(GO:0007412)
0.7	5.9	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.7	0.7	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.7	0.7	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.6	5.8	GO:0036158	outer dynein arm assembly(GO:0036158)
0.6	1.9	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.6	0.6	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.6	5.0	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.6	1.3	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.6	1.2	GO:1901642	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.6	0.6	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.6	1.8	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.6	1.8	GO:1904467	regulation of tumor necrosis factor secretion(GO:1904467) positive regulation of tumor necrosis factor secretion(GO:1904469) tumor necrosis factor secretion(GO:1990774)
0.6	1.8	GO:0048014	Tie signaling pathway(GO:0048014)
0.6	2.4	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.6	1.2	GO:0042756	drinking behavior(GO:0042756)
0.6	44.3	GO:0016358	dendrite development(GO:0016358)
0.6	1.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.6	1.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.6	12.4	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.6	1.2	GO:1903232	melanosome assembly(GO:1903232)
0.6	1.2	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.6	2.3	GO:0015858	nucleoside transport(GO:0015858)
0.6	2.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.6	1.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.6	2.3	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.6	4.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.6	7.5	GO:0001990	regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.6	5.2	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.6	1.1	GO:0015755	fructose transport(GO:0015755)
0.6	2.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.6	2.3	GO:0006689	ganglioside catabolic process(GO:0006689)
0.6	2.8	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.6	1.7	GO:0032484	Ral protein signal transduction(GO:0032484)
0.6	1.7	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.6	2.2	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.6	9.5	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.6	1.1	GO:0048664	neuron fate determination(GO:0048664)
0.6	1.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.6	0.6	GO:0060460	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.5	1.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.5	15.8	GO:0008333	endosome to lysosome transport(GO:0008333)
0.5	0.5	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.5	0.5	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.5	1.1	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.5	4.3	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5	1.1	GO:0015888	thiamine transport(GO:0015888)
0.5	1.6	GO:0046103	inosine biosynthetic process(GO:0046103)
0.5	2.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.5	2.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.5	3.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.5	7.5	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.5	0.5	GO:1902065	response to L-glutamate(GO:1902065)
0.5	1.6	GO:0060539	diaphragm development(GO:0060539)
0.5	4.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.5	2.6	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.5	2.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.5	1.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.5	1.5	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.5	1.5	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.5	2.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.5	0.5	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.5	2.5	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.5	3.0	GO:0009086	methionine biosynthetic process(GO:0009086)
0.5	1.0	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.5	1.0	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.5	2.0	GO:0016322	neuron remodeling(GO:0016322)
0.5	1.9	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.5	0.5	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.5	1.0	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.5	0.5	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.5	2.9	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5	0.5	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.5	2.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.5	1.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.5	1.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.5	1.0	GO:0048069	eye pigmentation(GO:0048069)
0.5	3.8	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.5	0.5	GO:0042363	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.5	0.9	GO:0001757	somite specification(GO:0001757)
0.5	1.4	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.5	1.4	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.5	0.9	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.5	1.4	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.5	2.8	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.5	2.7	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.5	0.9	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.5	3.2	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.4	0.9	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.4	1.3	GO:0006177	GMP biosynthetic process(GO:0006177)
0.4	2.7	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.4	3.6	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.4	1.8	GO:0006742	NADP catabolic process(GO:0006742)
0.4	0.9	GO:0070294	renal sodium ion absorption(GO:0070294)
0.4	2.6	GO:0030825	positive regulation of cGMP metabolic process(GO:0030825)
0.4	0.9	GO:2000399	negative regulation of thymocyte aggregation(GO:2000399)
0.4	2.2	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.4	0.4	GO:0048570	notochord morphogenesis(GO:0048570)
0.4	0.9	GO:0097503	sialylation(GO:0097503)
0.4	1.3	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.4	3.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.4	0.9	GO:1902896	terminal web assembly(GO:1902896)
0.4	3.0	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
0.4	1.3	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4	1.3	GO:0030578	PML body organization(GO:0030578)
0.4	0.4	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.4	1.3	GO:0097237	cellular response to toxic substance(GO:0097237)
0.4	0.8	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.4	1.6	GO:0007135	meiosis II(GO:0007135)
0.4	1.2	GO:0060468	prevention of polyspermy(GO:0060468)
0.4	0.4	GO:1904851	regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.4	0.4	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4	2.8	GO:0042989	sequestering of actin monomers(GO:0042989)
0.4	1.2	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4	0.4	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.4	0.4	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.4	0.8	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4	2.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4	1.2	GO:0016264	gap junction assembly(GO:0016264)
0.4	1.2	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.4	0.8	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.4	1.9	GO:0090042	tubulin deacetylation(GO:0090042)
0.4	1.9	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.4	3.8	GO:0018298	protein-chromophore linkage(GO:0018298)
0.4	1.1	GO:0034650	cortisol metabolic process(GO:0034650)
0.4	0.8	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.4	0.4	GO:0010966	regulation of phosphate transport(GO:0010966)
0.4	0.4	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
0.4	1.1	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.4	1.8	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.4	1.5	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.4	1.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.4	0.7	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.4	3.7	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.4	1.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.4	0.4	GO:0021794	thalamus development(GO:0021794)
0.4	1.8	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.4	1.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.4	1.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.4	0.4	GO:0042420	dopamine catabolic process(GO:0042420)
0.4	0.7	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.4	4.6	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3	0.3	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.3	4.2	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.3	0.7	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.3	1.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.3	0.7	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.3	3.1	GO:0001505	regulation of neurotransmitter levels(GO:0001505)
0.3	0.3	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3	0.3	GO:0009233	menaquinone metabolic process(GO:0009233)
0.3	0.7	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.3	0.3	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.3	1.3	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.3	0.3	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.3	1.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.3	0.3	GO:0045837	negative regulation of membrane potential(GO:0045837)
0.3	1.0	GO:0015747	urate transport(GO:0015747)
0.3	2.3	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3	0.6	GO:0060467	negative regulation of fertilization(GO:0060467)
0.3	0.6	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.3	1.3	GO:0090102	cochlea development(GO:0090102)
0.3	1.3	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.3	0.3	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3	0.3	GO:0061525	hindgut development(GO:0061525)
0.3	1.6	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.3	0.9	GO:1990928	response to amino acid starvation(GO:1990928)
0.3	3.0	GO:0021591	ventricular system development(GO:0021591)
0.3	3.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.3	0.6	GO:0033605	positive regulation of catecholamine secretion(GO:0033605)
0.3	0.6	GO:0043586	tongue development(GO:0043586)
0.3	3.6	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.3	1.2	GO:0051697	protein delipidation(GO:0051697)
0.3	0.6	GO:0035425	autocrine signaling(GO:0035425)
0.3	0.3	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.3	0.6	GO:1901858	regulation of mitochondrial DNA replication(GO:0090296) regulation of mitochondrial DNA metabolic process(GO:1901858)
0.3	0.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.3	0.3	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.3	0.3	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.3	0.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.3	0.6	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.3	1.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.3	0.8	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.3	0.8	GO:0022417	protein maturation by protein folding(GO:0022417)
0.3	0.6	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.3	0.5	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.3	1.3	GO:0046113	nucleobase catabolic process(GO:0046113)
0.3	1.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.3	0.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3	1.3	GO:0001778	plasma membrane repair(GO:0001778)
0.3	4.8	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.3	0.5	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3	0.8	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3	2.8	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.3	1.0	GO:0016139	glycoside catabolic process(GO:0016139)
0.3	1.3	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	0.5	GO:0018158	protein oxidation(GO:0018158)
0.3	0.8	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.3	1.3	GO:0080009	mRNA methylation(GO:0080009)
0.2	6.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.2	0.7	GO:0046078	dUMP metabolic process(GO:0046078)
0.2	1.9	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.2	1.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.2	0.7	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.2	2.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	1.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.5	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.2	1.0	GO:0016556	mRNA modification(GO:0016556)
0.2	0.5	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.2	5.6	GO:0034605	cellular response to heat(GO:0034605)
0.2	0.7	GO:0035092	sperm chromatin condensation(GO:0035092)
0.2	0.2	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.2	6.4	GO:0050808	synapse organization(GO:0050808)
0.2	0.2	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.2	0.7	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.2	0.2	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.2	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.2	0.2	GO:0014029	neural crest formation(GO:0014029)
0.2	0.4	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.2	0.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.2	1.5	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.2	0.4	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.2	9.0	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.2	0.6	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.2	1.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	0.4	GO:0051661	maintenance of centrosome location(GO:0051661)
0.2	0.2	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.2	0.8	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.2	1.2	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.2	0.6	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.6	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.2	0.2	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2	0.2	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2	10.3	GO:0006836	neurotransmitter transport(GO:0006836)
0.2	0.2	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2	0.4	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.2	0.2	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.2	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.2	0.5	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.2	0.2	GO:1990000	amyloid fibril formation(GO:1990000)
0.2	0.3	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	1.2	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2	0.8	GO:0030259	lipid glycosylation(GO:0030259)
0.2	2.8	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.2	0.3	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.2	0.3	GO:0031017	exocrine pancreas development(GO:0031017)
0.2	1.8	GO:0044458	motile cilium assembly(GO:0044458)
0.2	1.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.2	0.3	GO:0031077	post-embryonic camera-type eye development(GO:0031077)
0.2	0.8	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.3	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.2	0.2	GO:0072718	response to cisplatin(GO:0072718)
0.2	0.2	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.1	0.1	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	1.8	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.7	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	3.6	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.1	0.4	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.1	0.9	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1	4.0	GO:0031424	keratinization(GO:0031424)
0.1	6.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.1	GO:0010751	regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.7	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.1	0.5	GO:0045060	negative thymic T cell selection(GO:0045060)
0.1	0.4	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.1	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.8	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.1	0.4	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1	0.5	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.1	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1	0.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.7	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.2	GO:0006407	rRNA export from nucleus(GO:0006407)
0.1	0.2	GO:0002176	male germ cell proliferation(GO:0002176)
0.1	0.1	GO:0097048	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	4.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	0.1	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1	0.7	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.3	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.4	GO:1903624	regulation of DNA catabolic process(GO:1903624)
0.1	1.0	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.1	0.6	GO:0045056	transcytosis(GO:0045056)
0.1	0.2	GO:0072044	collecting duct development(GO:0072044)
0.1	1.8	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.2	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.1	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.1	0.1	GO:0060618	nipple development(GO:0060618)
0.1	0.2	GO:1903998	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.1	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.2	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.1	0.1	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.1	0.2	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.1	0.5	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	1.4	GO:0007340	acrosome reaction(GO:0007340)
0.1	0.1	GO:0035898	parathyroid hormone secretion(GO:0035898)
0.1	0.2	GO:0019532	oxalate transport(GO:0019532)
0.1	0.1	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1	0.2	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.1	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.1	GO:0015865	purine nucleotide transport(GO:0015865)
0.1	0.5	GO:0007220	Notch receptor processing(GO:0007220)
0.1	1.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.3	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.1	0.6	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.3	GO:0031000	response to caffeine(GO:0031000)
0.1	0.4	GO:0070528	protein kinase C signaling(GO:0070528)
0.1	1.0	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.2	GO:2001204	regulation of osteoclast development(GO:2001204)
0.1	0.2	GO:0033504	floor plate development(GO:0033504)
0.1	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.1	0.4	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.1	0.3	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	0.2	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.1	0.1	GO:0002767	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	1.5	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.1	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.1	0.4	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1	0.7	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.1	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.3	GO:0000132	establishment of mitotic spindle orientation(GO:0000132)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0019377	glycolipid catabolic process(GO:0019377)
0.1	0.1	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.0	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.2	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	1.8	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.1	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.0	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.5	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.0	GO:0070202	regulation of establishment of protein localization to chromosome(GO:0070202)
0.0	0.1	GO:0015846	polyamine transport(GO:0015846)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:0072148	epithelial cell fate commitment(GO:0072148)
0.0	0.0	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.1	GO:1904871	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.6	28.8	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
8.3	74.7	GO:0005883	neurofilament(GO:0005883)
7.0	28.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
6.7	80.5	GO:0043194	axon initial segment(GO:0043194)
5.9	17.7	GO:1990761	growth cone lamellipodium(GO:1990761)
5.9	5.9	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
5.7	45.8	GO:0043083	synaptic cleft(GO:0043083)
5.6	22.5	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
5.6	22.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
5.4	54.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
4.6	13.8	GO:0072534	perineuronal net(GO:0072534)
4.5	13.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
4.0	76.1	GO:0060077	inhibitory synapse(GO:0060077)
3.9	3.9	GO:0032279	asymmetric synapse(GO:0032279)
3.8	22.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
3.7	149.5	GO:0042734	presynaptic membrane(GO:0042734)
3.7	11.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
3.6	21.7	GO:0016012	sarcoglycan complex(GO:0016012)
3.5	78.0	GO:0048786	presynaptic active zone(GO:0048786)
3.5	21.3	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
3.4	3.4	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
3.4	13.5	GO:1990696	USH2 complex(GO:1990696)
3.3	9.8	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
3.3	29.4	GO:0036156	inner dynein arm(GO:0036156)
3.3	9.8	GO:0033010	paranodal junction(GO:0033010)
3.2	32.5	GO:0097539	ciliary transition fiber(GO:0097539)
3.2	86.9	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
3.2	70.5	GO:0032590	dendrite membrane(GO:0032590)
3.1	9.4	GO:0005594	collagen type IX trimer(GO:0005594)
3.0	12.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
3.0	41.5	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
2.9	14.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
2.9	8.6	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
2.9	71.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
2.8	11.1	GO:1990716	axonemal central apparatus(GO:1990716)
2.8	8.3	GO:0044294	dendritic growth cone(GO:0044294)
2.7	5.4	GO:1990635	proximal dendrite(GO:1990635)
2.6	7.9	GO:0005826	actomyosin contractile ring(GO:0005826)
2.6	26.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
2.5	25.4	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
2.4	9.8	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
2.4	134.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
2.4	329.5	GO:0045211	postsynaptic membrane(GO:0045211)
2.4	7.2	GO:0043511	inhibin complex(GO:0043511)
2.4	2.4	GO:0032589	neuron projection membrane(GO:0032589)
2.4	21.2	GO:0035253	ciliary rootlet(GO:0035253)
2.3	7.0	GO:0097427	microtubule bundle(GO:0097427)
2.3	28.0	GO:0032809	neuronal cell body membrane(GO:0032809)
2.2	13.3	GO:0045180	basal cortex(GO:0045180)
2.2	6.6	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
2.2	6.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
2.1	2.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
2.1	10.3	GO:0030122	AP-2 adaptor complex(GO:0030122)
2.1	121.5	GO:0030175	filopodium(GO:0030175)
2.0	4.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
2.0	7.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.0	23.5	GO:0031045	dense core granule(GO:0031045)
1.9	3.9	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.9	5.7	GO:0000802	transverse filament(GO:0000802)
1.9	5.7	GO:0005899	insulin receptor complex(GO:0005899)
1.9	3.8	GO:1990357	terminal web(GO:1990357)
1.9	7.5	GO:0032021	NELF complex(GO:0032021)
1.8	18.5	GO:0060091	kinocilium(GO:0060091)
1.8	14.6	GO:0042788	polysomal ribosome(GO:0042788)
1.8	5.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.8	3.5	GO:0043203	axon hillock(GO:0043203)
1.7	3.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
1.7	8.6	GO:0097433	dense body(GO:0097433)
1.7	12.0	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.7	6.9	GO:0045098	type III intermediate filament(GO:0045098)
1.7	8.5	GO:0070695	FHF complex(GO:0070695)
1.6	3.3	GO:0031258	lamellipodium membrane(GO:0031258)
1.6	4.7	GO:0036449	microtubule minus-end(GO:0036449)
1.6	6.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
1.5	4.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
1.5	5.9	GO:0035748	myelin sheath abaxonal region(GO:0035748)
1.4	113.2	GO:0030426	growth cone(GO:0030426)
1.4	5.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.4	8.6	GO:0031209	SCAR complex(GO:0031209)
1.4	8.4	GO:0032584	growth cone membrane(GO:0032584)
1.4	8.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
1.4	11.1	GO:0043198	dendritic shaft(GO:0043198)
1.4	4.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.3	1.3	GO:0005593	FACIT collagen trimer(GO:0005593)
1.3	194.4	GO:0098794	postsynapse(GO:0098794)
1.3	3.8	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.3	16.3	GO:0035686	sperm fibrous sheath(GO:0035686)
1.2	7.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.2	13.2	GO:0097431	mitotic spindle pole(GO:0097431)
1.2	1.2	GO:0097440	apical dendrite(GO:0097440)
1.2	2.3	GO:0033268	node of Ranvier(GO:0033268)
1.1	9.1	GO:0097542	ciliary tip(GO:0097542)
1.1	1.1	GO:0044308	axonal spine(GO:0044308)
1.1	3.2	GO:0032133	chromosome passenger complex(GO:0032133)
1.0	3.1	GO:0061689	tricellular tight junction(GO:0061689)
1.0	7.1	GO:0032593	insulin-responsive compartment(GO:0032593)
1.0	7.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.0	2.0	GO:0043196	varicosity(GO:0043196)
1.0	8.8	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.9	126.5	GO:0031225	anchored component of membrane(GO:0031225)
0.9	8.4	GO:0030061	mitochondrial crista(GO:0030061)
0.9	0.9	GO:0044298	cell body membrane(GO:0044298)
0.9	1.8	GO:0005955	calcineurin complex(GO:0005955)
0.9	26.7	GO:0005921	gap junction(GO:0005921)
0.9	0.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.9	2.6	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.9	1.7	GO:0002139	stereocilia coupling link(GO:0002139)
0.9	23.4	GO:0030315	T-tubule(GO:0030315)
0.8	6.6	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.8	2.4	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.8	9.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8	11.9	GO:0000930	gamma-tubulin complex(GO:0000930)
0.8	0.8	GO:0044393	microspike(GO:0044393)
0.8	2.4	GO:0070761	pre-snoRNP complex(GO:0070761)
0.8	2.4	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.8	11.7	GO:0005614	interstitial matrix(GO:0005614)
0.8	4.5	GO:0001674	female germ cell nucleus(GO:0001674)
0.7	8.2	GO:0042555	MCM complex(GO:0042555)
0.7	9.6	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.7	8.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.7	2.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7	4.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.7	41.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7	3.3	GO:0031983	vesicle lumen(GO:0031983)
0.7	3.9	GO:0001891	phagocytic cup(GO:0001891)
0.6	3.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.6	1.9	GO:0005606	laminin-1 complex(GO:0005606)
0.6	2.6	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.6	1.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.6	3.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.6	1.8	GO:1990393	3M complex(GO:1990393)
0.6	3.7	GO:0030897	HOPS complex(GO:0030897)
0.6	1.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.6	1.8	GO:0070939	Dsl1p complex(GO:0070939)
0.6	4.6	GO:0001520	outer dense fiber(GO:0001520)
0.6	28.2	GO:0001533	cornified envelope(GO:0001533)
0.6	2.8	GO:0071547	piP-body(GO:0071547)
0.6	1.7	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.5	139.0	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.5	3.2	GO:0005859	muscle myosin complex(GO:0005859)
0.5	35.4	GO:0008021	synaptic vesicle(GO:0008021)
0.5	14.7	GO:0005581	collagen trimer(GO:0005581)
0.5	0.5	GO:0044299	C-fiber(GO:0044299)
0.5	6.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.5	0.5	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.5	0.5	GO:0035838	growing cell tip(GO:0035838)
0.5	1.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.5	6.8	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.4	75.1	GO:0045202	synapse(GO:0045202)
0.4	2.4	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.4	2.7	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4	1.5	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.4	2.7	GO:0005688	U6 snRNP(GO:0005688)
0.4	1.1	GO:1990075	periciliary membrane compartment(GO:1990075)
0.4	1.5	GO:0044292	dendrite terminus(GO:0044292)
0.4	0.7	GO:0097441	basilar dendrite(GO:0097441)
0.3	1.7	GO:0005683	U7 snRNP(GO:0005683)
0.3	4.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.3	2.0	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3	4.5	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.3	0.8	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	1.1	GO:0071817	MMXD complex(GO:0071817)
0.3	0.8	GO:0055087	Ski complex(GO:0055087)
0.3	1.9	GO:0000800	lateral element(GO:0000800)
0.3	1.6	GO:0005687	U4 snRNP(GO:0005687)
0.3	0.8	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.3	2.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.3	0.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.2	57.5	GO:0043025	neuronal cell body(GO:0043025)
0.2	0.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.2	0.9	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.2	0.7	GO:0034706	sodium channel complex(GO:0034706)
0.2	0.6	GO:0034457	Mpp10 complex(GO:0034457)
0.2	1.0	GO:0005579	membrane attack complex(GO:0005579)
0.2	1.8	GO:0000242	pericentriolar material(GO:0000242)
0.2	1.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.2	0.6	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	1.3	GO:0036157	outer dynein arm(GO:0036157)
0.2	0.7	GO:0045293	mRNA editing complex(GO:0045293)
0.2	0.4	GO:0030478	actin cap(GO:0030478)
0.2	1.4	GO:0034464	BBSome(GO:0034464)
0.2	0.7	GO:0043202	lysosomal lumen(GO:0043202)
0.2	1.2	GO:0016272	prefoldin complex(GO:0016272)
0.2	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.2	2.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.2	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	3.7	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	1.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	0.8	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.1	0.2	GO:0044447	axoneme part(GO:0044447)
0.1	4.4	GO:0036477	somatodendritic compartment(GO:0036477)
0.1	0.2	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.6	GO:0000124	SAGA complex(GO:0000124)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.1	3.0	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.2	GO:0042629	mast cell granule(GO:0042629)
0.0	1.1	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.0	63.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
9.1	27.3	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
9.1	27.2	GO:0097109	neuroligin family protein binding(GO:0097109)
8.9	26.8	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
7.5	30.0	GO:0032051	clathrin light chain binding(GO:0032051)
7.2	21.7	GO:0004995	tachykinin receptor activity(GO:0004995)
7.1	35.6	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
7.0	34.8	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
6.8	27.3	GO:0038064	collagen receptor activity(GO:0038064)
6.6	26.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
6.5	19.6	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
6.5	19.4	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
6.1	18.2	GO:0048763	calcium-induced calcium release activity(GO:0048763)
5.9	35.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
5.9	64.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
5.4	16.3	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
5.3	10.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
5.2	36.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
5.1	20.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
5.0	15.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
4.9	88.7	GO:0005112	Notch binding(GO:0005112)
4.9	24.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.9	14.7	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
4.9	19.5	GO:0005042	netrin receptor activity(GO:0005042)
4.9	14.6	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
4.7	14.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
4.6	22.8	GO:0042609	CD4 receptor binding(GO:0042609)
4.5	17.9	GO:1904288	BAT3 complex binding(GO:1904288)
4.4	4.4	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
4.4	8.9	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
4.4	17.6	GO:0004065	arylsulfatase activity(GO:0004065)
4.4	17.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
4.3	13.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
4.2	8.5	GO:0097016	L27 domain binding(GO:0097016)
4.2	12.5	GO:0070699	type II activin receptor binding(GO:0070699)
4.0	20.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
4.0	128.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
4.0	20.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
4.0	15.9	GO:0034056	estrogen response element binding(GO:0034056)
4.0	19.9	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.0	7.9	GO:0005030	neurotrophin receptor activity(GO:0005030)
3.9	35.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
3.8	22.7	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
3.8	18.9	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
3.7	33.7	GO:0005003	ephrin receptor activity(GO:0005003)
3.7	11.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
3.6	47.1	GO:0015172	acidic amino acid transmembrane transporter activity(GO:0015172)
3.6	14.5	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
3.5	7.0	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
3.5	27.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
3.4	13.6	GO:0097001	ceramide binding(GO:0097001)
3.4	13.6	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
3.4	57.8	GO:0004890	GABA-A receptor activity(GO:0004890)
3.4	20.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
3.3	16.6	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
3.2	19.4	GO:0048495	Roundabout binding(GO:0048495)
3.2	16.0	GO:0001601	peptide YY receptor activity(GO:0001601)
3.2	25.4	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
3.1	9.4	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.1	12.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
3.1	9.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
3.0	9.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
3.0	39.5	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
3.0	11.9	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
3.0	3.0	GO:1990239	steroid hormone binding(GO:1990239)
2.9	8.8	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
2.9	75.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
2.9	20.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
2.8	56.8	GO:0017075	syntaxin-1 binding(GO:0017075)
2.8	8.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
2.8	8.5	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.8	19.6	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
2.7	16.4	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
2.6	18.5	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.6	21.1	GO:0034842	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
2.6	12.9	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
2.6	7.7	GO:0008046	axon guidance receptor activity(GO:0008046)
2.6	5.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
2.5	17.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.5	7.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
2.5	10.0	GO:0070052	collagen V binding(GO:0070052)
2.5	40.1	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
2.4	2.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
2.4	12.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
2.4	17.0	GO:0031995	insulin-like growth factor II binding(GO:0031995)
2.4	45.5	GO:0030215	semaphorin receptor binding(GO:0030215)
2.4	7.2	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
2.4	11.9	GO:0030506	ankyrin binding(GO:0030506)
2.4	4.7	GO:0004969	histamine receptor activity(GO:0004969)
2.4	7.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
2.3	9.3	GO:0030280	structural constituent of epidermis(GO:0030280)
2.2	8.9	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
2.2	6.6	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
2.2	6.6	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
2.2	65.6	GO:0001540	beta-amyloid binding(GO:0001540)
2.2	4.4	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
2.1	8.6	GO:0031750	D3 dopamine receptor binding(GO:0031750)
2.1	17.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.1	16.6	GO:0004383	guanylate cyclase activity(GO:0004383)
2.1	2.1	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
2.1	6.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
2.1	4.1	GO:0000146	microfilament motor activity(GO:0000146)
2.1	18.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.0	4.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
2.0	6.1	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
2.0	6.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.0	25.7	GO:0015026	coreceptor activity(GO:0015026)
2.0	11.7	GO:0031005	filamin binding(GO:0031005)
1.9	5.8	GO:0004977	melanocortin receptor activity(GO:0004977)
1.9	9.7	GO:0004565	beta-galactosidase activity(GO:0004565)
1.9	11.6	GO:0008517	folic acid transporter activity(GO:0008517)
1.9	26.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.9	20.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9	3.8	GO:0019211	phosphatase activator activity(GO:0019211)
1.9	26.0	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
1.8	5.5	GO:0031708	endothelin B receptor binding(GO:0031708)
1.8	7.2	GO:0004594	pantothenate kinase activity(GO:0004594)
1.8	7.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.8	3.6	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
1.8	17.9	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
1.8	7.1	GO:0015368	calcium:cation antiporter activity(GO:0015368)
1.8	33.7	GO:0005272	sodium channel activity(GO:0005272)
1.8	7.1	GO:0033142	progesterone receptor binding(GO:0033142)
1.7	17.4	GO:0050811	GABA receptor binding(GO:0050811)
1.7	46.9	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
1.7	24.0	GO:0030275	LRR domain binding(GO:0030275)
1.7	6.8	GO:0008179	adenylate cyclase binding(GO:0008179)
1.7	15.0	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
1.7	3.3	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
1.7	6.6	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.6	6.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
1.6	24.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
1.6	17.6	GO:0015643	toxic substance binding(GO:0015643)
1.6	1.6	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.6	17.3	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.6	4.7	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
1.6	7.8	GO:0019992	diacylglycerol binding(GO:0019992)
1.6	20.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.6	4.7	GO:0005275	amine transmembrane transporter activity(GO:0005275)
1.5	7.7	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.5	15.4	GO:0042577	lipid phosphatase activity(GO:0042577)
1.5	6.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.5	4.5	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.5	4.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
1.5	7.3	GO:0004945	angiotensin type II receptor activity(GO:0004945)
1.5	4.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
1.4	43.5	GO:0017147	Wnt-protein binding(GO:0017147)
1.4	10.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
1.4	61.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
1.4	5.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
1.4	7.2	GO:0031849	olfactory receptor binding(GO:0031849)
1.4	9.9	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.4	15.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
1.4	9.9	GO:0046790	virion binding(GO:0046790)
1.4	11.2	GO:0051011	microtubule minus-end binding(GO:0051011)
1.4	5.6	GO:0019871	sodium channel inhibitor activity(GO:0019871)
1.4	12.6	GO:0030553	cGMP binding(GO:0030553)
1.4	12.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
1.4	6.9	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.4	2.7	GO:0035939	microsatellite binding(GO:0035939)
1.4	6.8	GO:0004994	somatostatin receptor activity(GO:0004994)
1.4	1.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.4	6.8	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.4	6.8	GO:0004111	creatine kinase activity(GO:0004111)
1.3	1.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.3	58.1	GO:0005267	potassium channel activity(GO:0005267)
1.3	7.9	GO:0045545	syndecan binding(GO:0045545)
1.3	16.9	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
1.3	16.9	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
1.3	6.5	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.3	3.9	GO:0004924	oncostatin-M receptor activity(GO:0004924)
1.3	26.9	GO:0046875	ephrin receptor binding(GO:0046875)
1.3	7.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3	5.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
1.3	5.1	GO:0034711	inhibin binding(GO:0034711)
1.3	8.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
1.2	2.5	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.2	1.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
1.2	6.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.2	19.8	GO:0003785	actin monomer binding(GO:0003785)
1.2	17.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
1.2	4.9	GO:0030249	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
1.2	13.3	GO:0005351	sugar:proton symporter activity(GO:0005351)
1.2	11.9	GO:0071837	HMG box domain binding(GO:0071837)
1.2	5.9	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.2	4.7	GO:0031628	opioid receptor binding(GO:0031628)
1.2	5.8	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
1.2	25.5	GO:0005540	hyaluronic acid binding(GO:0005540)
1.2	9.3	GO:0042923	neuropeptide binding(GO:0042923)
1.2	3.5	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
1.2	1.2	GO:0004985	opioid receptor activity(GO:0004985)
1.1	3.4	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.1	4.6	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
1.1	5.7	GO:0034190	apolipoprotein receptor binding(GO:0034190)
1.1	13.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.1	25.8	GO:0030507	spectrin binding(GO:0030507)
1.1	4.5	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
1.1	3.3	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
1.1	14.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
1.1	9.9	GO:0048018	receptor agonist activity(GO:0048018)
1.1	2.2	GO:0043546	molybdopterin cofactor binding(GO:0043546)
1.1	5.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.0	3.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.0	1.0	GO:0022835	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
1.0	99.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
1.0	13.1	GO:0032183	SUMO binding(GO:0032183)
1.0	17.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
1.0	37.1	GO:0019111	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
1.0	3.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.0	2.9	GO:0048406	nerve growth factor binding(GO:0048406)
1.0	4.8	GO:0004957	prostaglandin E receptor activity(GO:0004957)
1.0	2.9	GO:0004946	bombesin receptor activity(GO:0004946)
0.9	6.6	GO:0033691	sialic acid binding(GO:0033691)
0.9	2.8	GO:0005148	prolactin receptor binding(GO:0005148)
0.9	12.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.9	0.9	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.9	7.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.9	2.8	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.9	14.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.9	0.9	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.9	9.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.9	3.7	GO:0008502	melatonin receptor activity(GO:0008502)
0.9	5.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.9	18.0	GO:0043813	phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.9	0.9	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.9	22.1	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.9	8.7	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.9	5.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.9	2.6	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.9	2.6	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.8	14.8	GO:0052712	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.8	8.8	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.8	1.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.8	40.0	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.8	18.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.8	14.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.8	1.6	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.8	2.3	GO:1990460	leptin receptor binding(GO:1990460)
0.8	7.7	GO:0005522	profilin binding(GO:0005522)
0.8	8.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.8	0.8	GO:0008579	JUN kinase phosphatase activity(GO:0008579)
0.8	2.3	GO:2001069	glycogen binding(GO:2001069)
0.8	2.3	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.7	0.7	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.7	5.2	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.7	2.2	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.7	5.8	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.7	7.9	GO:0004707	MAP kinase activity(GO:0004707)
0.7	8.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7	1.4	GO:0038191	neuropilin binding(GO:0038191)
0.7	5.4	GO:0051787	misfolded protein binding(GO:0051787)
0.7	4.8	GO:0043719	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.7	13.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.7	13.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.6	3.2	GO:0017040	ceramidase activity(GO:0017040)
0.6	5.7	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6	5.7	GO:0045295	gamma-catenin binding(GO:0045295)
0.6	3.6	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.6	3.0	GO:0071723	lipopeptide binding(GO:0071723)
0.6	0.6	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.6	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.6	4.1	GO:0048185	activin binding(GO:0048185)
0.6	7.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.6	1.8	GO:0030151	molybdenum ion binding(GO:0030151)
0.6	2.9	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6	21.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6	0.6	GO:0043823	fluorene oxygenase activity(GO:0018585) mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.6	2.3	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.6	1.1	GO:0034618	arginine binding(GO:0034618)
0.6	1.7	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.6	1.7	GO:0071209	U7 snRNA binding(GO:0071209)
0.6	6.7	GO:0019215	intermediate filament binding(GO:0019215)
0.6	0.6	GO:0038100	nodal binding(GO:0038100)
0.6	1.1	GO:0043495	protein anchor(GO:0043495)
0.5	2.7	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.5	7.1	GO:0005243	gap junction channel activity(GO:0005243)
0.5	1.6	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.5	1.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.5	2.1	GO:0043237	laminin-1 binding(GO:0043237)
0.5	1.1	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.5	2.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.5	7.3	GO:0043274	phospholipase binding(GO:0043274)
0.5	42.0	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.5	2.6	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.5	3.6	GO:0002162	dystroglycan binding(GO:0002162)
0.5	33.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5	10.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.5	1.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.5	2.5	GO:0070883	pre-miRNA binding(GO:0070883)
0.5	1.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.5	3.5	GO:0003688	DNA replication origin binding(GO:0003688)
0.5	2.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.5	1.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.5	2.9	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.5	1.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5	1.4	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5	2.8	GO:0008301	DNA binding, bending(GO:0008301)
0.5	1.4	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5	7.9	GO:0042165	neurotransmitter binding(GO:0042165)
0.5	10.1	GO:0017046	peptide hormone binding(GO:0017046)
0.5	1.8	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.5	0.5	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.5	1.8	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.4	3.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.4	0.4	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4	4.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.4	1.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.4	1.7	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4	2.6	GO:0003680	AT DNA binding(GO:0003680)
0.4	2.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.4	1.7	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.4	19.8	GO:0017022	myosin binding(GO:0017022)
0.4	5.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.4	1.7	GO:0050815	phosphoserine binding(GO:0050815)
0.4	5.0	GO:0019841	retinol binding(GO:0019841)
0.4	1.7	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.4	0.8	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.4	0.8	GO:0070878	primary miRNA binding(GO:0070878)
0.4	4.4	GO:0070628	proteasome binding(GO:0070628)
0.4	0.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.4	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.4	4.4	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4	8.3	GO:0042169	SH2 domain binding(GO:0042169)
0.4	2.7	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4	12.4	GO:0070888	E-box binding(GO:0070888)
0.4	0.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4	1.2	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.4	0.8	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.4	1.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.4	6.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.4	0.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.4	2.3	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.4	1.5	GO:0102344	3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4	0.4	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.4	3.7	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4	7.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.4	4.3	GO:0031404	chloride ion binding(GO:0031404)
0.4	1.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4	0.4	GO:0051378	serotonin binding(GO:0051378)
0.4	1.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.4	0.7	GO:0031433	telethonin binding(GO:0031433)
0.3	1.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3	1.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	76.0	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3	1.4	GO:0043842	Kdo transferase activity(GO:0043842)
0.3	10.5	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3	1.3	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.3	3.0	GO:0009881	photoreceptor activity(GO:0009881)
0.3	2.9	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.3	0.6	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3	3.7	GO:0004000	adenosine deaminase activity(GO:0004000)
0.3	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3	3.0	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.3	1.2	GO:0016936	galactoside binding(GO:0016936)
0.3	1.2	GO:0030619	U1 snRNA binding(GO:0030619)
0.3	3.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.3	1.4	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.3	2.6	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	1.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.3	0.6	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.3	1.1	GO:0033265	choline binding(GO:0033265)
0.3	3.3	GO:0051183	vitamin transporter activity(GO:0051183)
0.3	1.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.3	0.5	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	1.1	GO:0019808	polyamine binding(GO:0019808)
0.3	2.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.3	1.0	GO:1990226	histone methyltransferase binding(GO:1990226)
0.3	0.8	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.3	1.8	GO:0050786	RAGE receptor binding(GO:0050786)
0.3	97.5	GO:0005509	calcium ion binding(GO:0005509)
0.2	2.0	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.2	0.5	GO:0019862	IgA binding(GO:0019862)
0.2	0.9	GO:0070097	delta-catenin binding(GO:0070097)
0.2	0.9	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.2	0.6	GO:0016004	phospholipase activator activity(GO:0016004)
0.2	1.2	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2	3.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	1.8	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.2	0.8	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.2	0.6	GO:0048019	receptor antagonist activity(GO:0048019)
0.2	4.2	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2	1.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.2	0.6	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.2	1.0	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.2	1.8	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	0.2	GO:0045503	dynein light chain binding(GO:0045503)
0.2	3.5	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2	0.8	GO:0051393	alpha-actinin binding(GO:0051393)
0.2	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	0.4	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2	0.7	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.2	0.5	GO:0035514	DNA demethylase activity(GO:0035514)
0.2	4.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	2.9	GO:0042056	chemoattractant activity(GO:0042056)
0.2	7.1	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.2	0.5	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	0.8	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	13.1	GO:0008083	growth factor activity(GO:0008083)
0.2	0.3	GO:0032405	MutLalpha complex binding(GO:0032405)
0.2	12.3	GO:0005516	calmodulin binding(GO:0005516)
0.2	4.7	GO:0008009	chemokine activity(GO:0008009)
0.2	1.1	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.1	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.1	0.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.7	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.8	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.9	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.6	GO:0002054	nucleobase binding(GO:0002054)
0.1	1.9	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	0.5	GO:0008378	galactosyltransferase activity(GO:0008378)
0.1	1.6	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	0.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.5	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.3	GO:0030984	kininogen binding(GO:0030984)
0.1	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.1	20.8	GO:0003779	actin binding(GO:0003779)
0.1	0.9	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	3.5	GO:0043022	ribosome binding(GO:0043022)
0.1	0.3	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.1	1.5	GO:0005537	mannose binding(GO:0005537)
0.1	0.5	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.7	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.1	1.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.2	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.2	GO:0030519	snoRNP binding(GO:0030519)
0.1	0.2	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.3	GO:0015276	ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.1	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	2.8	GO:0044823	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.1	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	20.7	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.4	GO:0005550	pheromone binding(GO:0005550)
0.0	0.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.3	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.0	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.4	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0	0.0	GO:0043918	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0005402	cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	3.4	GO:0005549	odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	5.6	PID IGF1 PATHWAY	IGF1 pathway
3.8	7.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
2.6	83.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
2.3	46.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
2.1	58.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
2.0	10.2	PID EPHB FWD PATHWAY	EPHB forward signaling
1.8	42.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.6	1.6	PID VEGFR1 PATHWAY	VEGFR1 specific signals
1.5	3.1	PID S1P S1P3 PATHWAY	S1P3 pathway
1.5	12.0	ST G ALPHA S PATHWAY	G alpha s Pathway
1.4	41.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
1.4	31.3	PID EPHA FWDPATHWAY	EPHA forward signaling
1.4	2.7	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.4	52.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
1.3	2.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.3	37.5	SIG CHEMOTAXIS	Genes related to chemotaxis
1.3	19.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.2	21.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.1	31.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.1	6.5	PID ENDOTHELIN PATHWAY	Endothelins
1.0	21.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.0	13.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.0	48.3	PID NOTCH PATHWAY	Notch signaling pathway
1.0	1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.9	10.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.9	14.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.8	4.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8	12.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.7	7.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	0.7	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.6	6.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	9.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.6	94.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.6	9.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.5	22.5	NABA COLLAGENS	Genes encoding collagen proteins
0.5	9.4	PID ARF 3PATHWAY	Arf1 pathway
0.5	17.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	107.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5	12.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.5	5.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	0.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5	4.3	PID ALK2 PATHWAY	ALK2 signaling events
0.5	14.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.4	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	108.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.4	1.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.4	6.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.4	3.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.4	1.8	PID IL3 PATHWAY	IL3-mediated signaling events
0.3	2.1	PID REELIN PATHWAY	Reelin signaling pathway
0.3	6.6	PID INSULIN PATHWAY	Insulin Pathway
0.3	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	1.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.3	8.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	7.9	PID LKB1 PATHWAY	LKB1 signaling events
0.2	2.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	20.1	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.1	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	0.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	61.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
4.7	42.5	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
4.4	34.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
4.1	57.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
4.1	16.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
3.9	58.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
3.7	158.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
3.7	3.7	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
3.6	39.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
3.3	3.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
3.3	45.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.8	8.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
2.8	5.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
2.8	73.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
2.7	5.5	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
2.7	2.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
2.6	26.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
2.6	60.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
2.5	27.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
2.5	35.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.4	4.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
2.3	25.7	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
2.2	15.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
2.2	6.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
2.1	23.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
2.1	16.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
2.1	77.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
2.0	78.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
2.0	22.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
2.0	45.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
1.8	23.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.7	12.0	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.7	38.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.6	59.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
1.5	4.5	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.5	34.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.5	35.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
1.4	27.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
1.4	11.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.4	14.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
1.4	12.8	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
1.4	15.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.4	8.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
1.3	17.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.3	22.8	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
1.3	28.9	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
1.3	16.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
1.2	22.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.2	23.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
1.2	12.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.2	17.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
1.1	12.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.1	14.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
1.1	28.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.1	7.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
1.1	12.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
1.0	22.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
1.0	1.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.0	4.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.0	10.9	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
1.0	14.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.9	8.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.9	1.8	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.9	10.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.8	2.4	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.8	29.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.8	7.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.7	4.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.7	10.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.7	3.5	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.7	6.3	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.7	34.3	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.6	2.3	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.6	4.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6	6.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.6	11.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.5	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.5	82.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.5	1.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.5	1.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.5	4.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	1.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.5	6.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.5	4.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.5	6.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5	6.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5	5.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.4	3.4	REACTOME OPSINS	Genes involved in Opsins
0.4	5.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.4	1.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.4	1.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	5.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3	9.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3	4.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	3.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.3	0.6	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.3	5.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	3.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	0.8	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.3	1.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.3	16.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	5.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	0.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	6.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	5.0	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.2	4.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	2.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	1.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1	1.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.6	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping

Results for Nhlh1

Z-value: 7.75

Motif logo

Transcription factors associated with Nhlh1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nhlh1 motif across conditions

Conditions sorted by the z-value of the Nhlh1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nhlh1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: