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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nkx2-3

Z-value: 2.23

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Transcription factors associated with Nkx2-3

Gene Symbol	Gene ID	Gene Info
Nkx2-3 Ensembl NCBI MGI UniProt	ENSMUSG00000044220.12	NK2 homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_43616627_43617285	Nkx2-3	4631	0.121111	0.67	1.9e-08	Click!
chr19_43616398_43616585	Nkx2-3	4166	0.125712	0.66	3.2e-08	Click!
chr19_43616167_43616368	Nkx2-3	3942	0.128428	0.65	9.5e-08	Click!
chr19_43615213_43615390	Nkx2-3	2976	0.146854	0.56	8.0e-06	Click!
chr19_43614850_43615114	Nkx2-3	2657	0.157168	0.55	1.4e-05	Click!

Activity of the Nkx2-3 motif across conditions

Conditions sorted by the z-value of the Nkx2-3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_74194149_74194481	11.17	Gm15387	predicted gene 15387	99982	0.07
chrX_58445733_58445903	8.96	Gm14645	predicted gene 14645	17743	0.26
chr12_39301586_39301824	8.93	Gm18591	predicted gene, 18591	92813	0.08
chr10_102238764_102238956	8.72	Mgat4c	MGAT4 family, member C	79781	0.1
chr6_107711195_107711474	8.07	4933431M02Rik	RIKEN cDNA 4933431M02 gene	83560	0.1
chr13_107247476_107247653	7.65	Gm2726	predicted gene 2726	32627	0.2
chr3_6886780_6886981	7.61	Gm22074	predicted gene, 22074	90388	0.09
chr6_127701185_127701975	7.01	Gm43634	predicted gene 43634	57140	0.08
chr17_65961618_65962124	6.75	Ankrd12	ankyrin repeat domain 12	10521	0.14
chr3_139885937_139886924	6.67	Gm43678	predicted gene 43678	73666	0.11
chr1_29217161_29217338	6.23	Gm18033	predicted gene, 18033	2451	0.41
chr8_98573232_98573407	5.97	Gm23494	predicted gene, 23494	101883	0.08
chr9_50245051_50245269	5.87	2310003N18Rik	RIKEN cDNA 2310003N18 gene	11978	0.19
chr1_59394623_59395231	5.87	Gm29016	predicted gene 29016	15997	0.18
chr3_3832009_3832194	5.65	Gm2071	predicted gene 2071	2817	0.34
chr9_99994460_99994673	5.64	4930519F24Rik	RIKEN cDNA 4930519F24 gene	27734	0.17
chr13_84056961_84057458	5.62	Gm17750	predicted gene, 17750	7563	0.22
chr14_123065129_123065306	5.51	AA536875	expressed sequence AA536875	21935	0.22
chr13_77892438_77892993	5.51	Pou5f2	POU domain class 5, transcription factor 2	132187	0.05
chrX_93310672_93310849	5.41	Arx	aristaless related homeobox	24250	0.21
chr14_59737148_59737645	5.29	Gm19716	predicted gene, 19716	94848	0.07
chr14_123065358_123065532	5.29	AA536875	expressed sequence AA536875	22163	0.22
chr12_27076136_27076315	5.28	Gm9866	predicted gene 9866	38770	0.22
chr14_62415985_62416195	5.24	Gucy1b2	guanylate cyclase 1, soluble, beta 2	38703	0.13
chr6_138419995_138420190	5.22	Lmo3	LIM domain only 3	1360	0.42
chr5_42067440_42068088	5.20	Gm16223	predicted gene 16223	196	0.97
chr13_83985066_83985623	5.13	Gm4241	predicted gene 4241	2647	0.28
chr14_12876868_12877121	5.07	Gm5457	predicted pseudogene 5457	9441	0.24
chr16_63747767_63748162	5.05	Gm22769	predicted gene, 22769	430	0.91
chr2_117439884_117440216	5.03	Gm13982	predicted gene 13982	22353	0.24
chr3_26641406_26641733	5.00	Spata16	spermatogenesis associated 16	3919	0.29
chr1_78167977_78168321	4.95	Pax3	paired box 3	28689	0.2
chr2_101592687_101592869	4.91	B230118H07Rik	RIKEN cDNA B230118H07 gene	7844	0.19
chr17_66869624_66870037	4.90	Gm49940	predicted gene, 49940	7590	0.18
chr5_40295141_40295321	4.89	Gm2810	predicted pseudogene 2810	33207	0.24
chr14_105851771_105851979	4.87	Gm48970	predicted gene, 48970	10626	0.21
chr13_83750227_83750397	4.85	C130071C03Rik	RIKEN cDNA C130071C03 gene	11449	0.12
chr5_44473970_44474128	4.79	Gm42981	predicted gene 42981	21372	0.13
chr10_69465967_69466180	4.77	Gm18636	predicted gene, 18636	42325	0.15
chr9_100686243_100686394	4.75	Gm38297	predicted gene, 38297	16895	0.16
chr10_19310105_19310477	4.74	Gm33056	predicted gene, 33056	19302	0.19
chr14_12338097_12338549	4.73	Gm24578	predicted gene, 24578	4419	0.14
chr9_65267989_65268185	4.72	Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	2264	0.19
chr13_36283484_36283656	4.68	Gm48766	predicted gene, 48766	31211	0.17
chr7_132731406_132731752	4.67	Fam53b	family with sequence similarity 53, member B	45337	0.12
chr3_6886610_6886763	4.66	Gm22074	predicted gene, 22074	90582	0.09
chr16_77291582_77292053	4.66	Gm31258	predicted gene, 31258	13743	0.19
chr14_115082136_115082318	4.64	Gpc5	glypican 5	9988	0.13
chr17_17409158_17409446	4.60	Gm26873	predicted gene, 26873	2691	0.21
chr17_88763479_88763727	4.59	Lhcgr	luteinizing hormone/choriogonadotropin receptor	10453	0.24
chr12_50190972_50191191	4.59	Gm40418	predicted gene, 40418	70772	0.14
chr14_100714045_100714196	4.57	Gm22401	predicted gene, 22401	13499	0.21
chr13_77893040_77893199	4.56	Pou5f2	POU domain class 5, transcription factor 2	131783	0.05
chr11_40456488_40456834	4.53	3110004A20Rik	RIKEN cDNA 3110004A20 gene	19016	0.17
chr18_57704186_57704540	4.50	Gm44491	predicted gene, 44491	22549	0.17
chr3_11261156_11261347	4.48	Gm22547	predicted gene, 22547	106914	0.08
chr3_26640780_26641306	4.45	Spata16	spermatogenesis associated 16	3393	0.31
chr10_29143863_29144732	4.44	Gm9996	predicted gene 9996	103	0.69
chr6_47229035_47229229	4.44	Cntnap2	contactin associated protein-like 2	15255	0.28
chr12_27151151_27151367	4.43	Gm9866	predicted gene 9866	9052	0.3
chr5_103161672_103161823	4.43	Mapk10	mitogen-activated protein kinase 10	44182	0.17
chr5_13414234_13414411	4.42	Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	14745	0.24
chr13_99444397_99444879	4.39	Map1b	microtubule-associated protein 1B	171	0.95
chr5_111944379_111944557	4.37	Gm42488	predicted gene 42488	233	0.96
chr4_5962411_5962640	4.37	Gm11796	predicted gene 11796	107038	0.07
chr14_75473074_75473492	4.37	Siah3	siah E3 ubiquitin protein ligase family member 3	17301	0.22
chr6_15397521_15397861	4.36	Gm25470	predicted gene, 25470	7290	0.26
chr14_75236389_75236560	4.35	Cpb2	carboxypeptidase B2 (plasma)	5813	0.15
chr15_85463386_85463550	4.35	7530416G11Rik	RIKEN cDNA 7530416G11 gene	39759	0.14
chr16_89530496_89531006	4.33	Krtap7-1	keratin associated protein 7-1	22428	0.15
chr7_97391358_97391780	4.33	Alg8	asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)	791	0.53
chr13_112165997_112166183	4.31	Gm48802	predicted gene, 48802	5978	0.21
chr5_106577659_106577832	4.29	Gm29464	predicted gene 29464	2870	0.18
chr10_91514578_91514763	4.23	Gm47084	predicted gene, 47084	66290	0.12
chr2_51087621_51088075	4.21	Rnd3	Rho family GTPase 3	61246	0.13
chr15_44705846_44706012	4.20	Sybu	syntabulin (syntaxin-interacting)	41859	0.15
chr13_72298631_72298782	4.19	Gm4052	predicted gene 4052	51515	0.15
chr1_46830172_46830391	4.19	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5618	0.22
chr15_88315161_88315318	4.18	B230214G05Rik	RIKEN cDNA B230214G05 gene	365	0.51
chr18_46067126_46067291	4.17	A330093E20Rik	RIKEN cDNA A330093E20 gene	21948	0.2
chr8_69149162_69149554	4.17	Lzts1	leucine zipper, putative tumor suppressor 1	8405	0.17
chr1_194226946_194227113	4.15	4930503O07Rik	RIKEN cDNA 4930503O07 gene	4270	0.36
chr15_22152009_22152160	4.13	Gm27525	predicted gene, 27525	121986	0.06
chr13_99443818_99444236	4.13	Map1b	microtubule-associated protein 1B	83	0.97
chr8_36014873_36015024	4.12	Rps12-ps24	ribosomal protein S12, pseudogene 24	10805	0.2
chr3_120342836_120343020	4.11	Gm23733	predicted gene, 23733	24939	0.27
chr19_15803250_15803445	4.10	Gm50348	predicted gene, 50348	289	0.94
chr10_25024228_25024379	4.10	Gm47715	predicted gene, 47715	24283	0.15
chr12_68217227_68217378	4.09	Gm47454	predicted gene, 47454	115320	0.06
chr5_81359614_81359973	4.08	Adgrl3	adhesion G protein-coupled receptor L3	49768	0.18
chr7_69572988_69573508	4.08	Gm44535	predicted gene 44535	6460	0.22
chr13_36283759_36283936	4.07	Gm48766	predicted gene, 48766	31488	0.17
chr4_125545547_125545968	4.07	Mir692-2	microRNA 692-2	41008	0.15
chr6_116397661_116398032	4.05	Marchf8	membrane associated ring-CH-type finger 8	5146	0.13
chr15_26275989_26276253	4.04	Marchf11	membrane associated ring-CH-type finger 11	32927	0.23
chr13_84752343_84752734	4.04	Gm26913	predicted gene, 26913	61597	0.15
chr16_91140532_91140860	4.04	Gm49612	predicted gene, 49612	5220	0.12
chr16_59854456_59854822	4.03	Epha6	Eph receptor A6	151082	0.04
chr3_156904026_156904232	4.00	Gm15577	predicted gene 15577	16651	0.23
chr3_66746460_66746680	3.99	Gm6555	predicted gene 6555	135780	0.05
chr16_52387159_52387325	3.99	Alcam	activated leukocyte cell adhesion molecule	65223	0.14
chr2_152048577_152049360	3.98	AA387200	expressed sequence AA387200	27840	0.11
chr1_20428787_20428938	3.98	Gm15795	predicted gene 15795	15948	0.17
chr17_4177609_4177825	3.98	4930548J01Rik	RIKEN cDNA 4930548J01 gene	55604	0.16
chr2_56539846_56540169	3.98	Mir195b	microRNA 195b	245804	0.02
chr8_48322987_48323138	3.97	Tenm3	teneurin transmembrane protein 3	22963	0.23
chr2_140669081_140669241	3.97	Flrt3	fibronectin leucine rich transmembrane protein 3	2239	0.46
chr2_40643950_40644201	3.96	Lrp1b	low density lipoprotein-related protein 1B	13313	0.29
chr3_118664419_118664570	3.95	Dpyd	dihydropyrimidine dehydrogenase	102308	0.07
chr3_115856880_115857079	3.92	Dph5	diphthamide biosynthesis 5	30858	0.11
chr16_63278367_63278696	3.92	Gm33912	predicted gene, 33912	61089	0.15
chr13_89881342_89881539	3.92	Gm24498	predicted gene, 24498	46103	0.17
chrX_22950779_22950930	3.92	Gm26131	predicted gene, 26131	88918	0.1
chr10_83106435_83106654	3.91	1700025N21Rik	RIKEN cDNA 1700025N21 gene	35494	0.15
chr2_41498755_41498942	3.90	Lrp1b	low density lipoprotein-related protein 1B	290230	0.01
chr4_54331384_54331565	3.90	Gm12469	predicted gene 12469	95598	0.08
chr14_58101525_58101676	3.88	Gm17109	predicted gene 17109	4529	0.22
chr12_33035439_33035619	3.88	Cdhr3	cadherin-related family member 3	17457	0.14
chr4_148291962_148292123	3.87	Disp3	dispatched RND transporter family member 3	4077	0.19
chr7_54782042_54782216	3.84	Luzp2	leucine zipper protein 2	53369	0.15
chr8_97477153_97477340	3.84	Gm5913	predicted gene 5913	48136	0.17
chr14_16200927_16201541	3.84	Rpl31-ps3	ribosomal protein L31, pseudogene 3	23789	0.13
chr10_92556536_92557110	3.83	Gm4800	predicted gene 4800	13153	0.16
chr6_15639488_15639689	3.81	Gm44039	predicted gene, 44039	3464	0.35
chr2_10525644_10525960	3.80	Mir669h	microRNA 669h	7647	0.01
chr2_80129220_80129421	3.80	Pde1a	phosphodiesterase 1A, calmodulin-dependent	138	0.96
chr8_99414741_99415068	3.80	Cdh8	cadherin 8	1415	0.4
chr4_39345356_39345507	3.78	Gm23607	predicted gene, 23607	49968	0.14
chr1_6734835_6735004	3.78	St18	suppression of tumorigenicity 18	49	0.99
chr4_27429531_27429705	3.78	Gm11901	predicted gene 11901	113560	0.07
chr10_59090684_59090879	3.77	Sh3rf3	SH3 domain containing ring finger 3	10747	0.24
chr9_26690126_26690338	3.77	Gm48393	predicted gene, 48393	40942	0.15
chr14_19720139_19720325	3.77	Gm49341	predicted gene, 49341	23023	0.12
chr1_66320866_66321435	3.76	Map2	microtubule-associated protein 2	569	0.75
chr14_11960676_11960864	3.75	Gm3848	predicted gene 3848	20438	0.22
chr8_23562129_23562317	3.74	Zmat4	zinc finger, matrin type 4	73796	0.11
chr3_56981029_56981302	3.74	Gm22269	predicted gene, 22269	72985	0.12
chr14_22037282_22037433	3.74	Gm7480	predicted gene 7480	1254	0.4
chr14_9597570_9597992	3.71	Gm48371	predicted gene, 48371	128226	0.06
chr3_42111396_42111547	3.70	Gm37846	predicted gene, 37846	52394	0.16
chr8_12126666_12127044	3.70	A230072I06Rik	RIKEN cDNA A230072I06 gene	151964	0.03
chr12_48284505_48284715	3.70	Gm48587	predicted gene, 48587	210609	0.02
chr5_70842284_70842796	3.69	Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	77	0.99
chr1_137373621_137374166	3.69	Gm23534	predicted gene, 23534	6646	0.26
chr4_53253649_53254014	3.69	4930522O17Rik	RIKEN cDNA 4930522O17 gene	7635	0.18
chr2_51831341_51831505	3.68	Gm13492	predicted gene 13492	12854	0.2
chr5_40295409_40295582	3.68	Gm2810	predicted pseudogene 2810	32943	0.24
chr1_67558856_67559007	3.68	Kif22-ps	kinesin family member 22, pseudogene	26122	0.23
chr10_18360177_18360562	3.65	Gm18942	predicted gene, 18942	23128	0.17
chr2_56257440_56257969	3.64	Gm13518	predicted gene 13518	217851	0.02
chr6_6604244_6604395	3.64	Sem1	SEM1, 26S proteasome complex subunit	25656	0.18
chr2_49719024_49719250	3.62	Kif5c	kinesin family member 5C	3430	0.29
chr14_35244974_35245125	3.62	Gm49034	predicted gene, 49034	25611	0.26
chr6_17796921_17797464	3.62	Gm26738	predicted gene, 26738	37993	0.12
chr16_79870693_79870877	3.61	Rps19-ps12	ribosomal protein S19, pseudogene 12	44086	0.2
chr15_26021931_26022113	3.59	Zfp622	zinc finger protein 622	26986	0.18
chr15_84812869_84813054	3.59	Phf21b	PHD finger protein 21B	9404	0.18
chr14_35112923_35113111	3.59	Gm49034	predicted gene, 49034	106421	0.07
chr10_70952624_70952802	3.59	Bicc1	BicC family RNA binding protein 1	4224	0.2
chr6_54554355_54554906	3.58	Scrn1	secernin 1	175	0.95
chr15_95217343_95217494	3.58	1700129L04Rik	RIKEN cDNA 1700129L04 gene	55024	0.17
chr10_38103605_38103756	3.58	Gm31378	predicted gene, 31378	18381	0.22
chr12_33035669_33036432	3.58	Cdhr3	cadherin-related family member 3	16936	0.14
chr7_96865260_96865776	3.58	Gm25712	predicted gene, 25712	2139	0.28
chr2_152069243_152069466	3.57	AA387200	expressed sequence AA387200	7454	0.15
chr2_171847235_171847407	3.57	1700028P15Rik	RIKEN cDNA 1700028P15 gene	114810	0.06
chr14_13651882_13652062	3.57	Sntn	sentan, cilia apical structure protein	18904	0.24
chr10_52742737_52743261	3.56	Gm47624	predicted gene, 47624	49161	0.11
chr14_59737850_59738006	3.55	Gm19716	predicted gene, 19716	95380	0.07
chr14_38825108_38825292	3.55	Nrg3os	neuregulin 3, opposite strand	73102	0.12
chr12_39027318_39027481	3.54	Gm19563	predicted gene, 19563	28745	0.18
chr7_74687903_74688273	3.54	Gm7726	predicted gene 7726	11768	0.26
chr6_50777784_50778006	3.54	C530044C16Rik	RIKEN cDNA C530044C16 gene	1571	0.34
chrX_93377714_93377865	3.54	Arx	aristaless related homeobox	91279	0.08
chr4_138689318_138689498	3.54	Pla2g2c	phospholipase A2, group IIC	35384	0.12
chr12_39301178_39301567	3.53	Gm18591	predicted gene, 18591	92480	0.08
chr14_12346462_12346680	3.52	Fezf2	Fez family zinc finger 2	612	0.63
chr19_14777449_14777621	3.52	Gm26026	predicted gene, 26026	59055	0.15
chr14_62003120_62003302	3.51	Gm47953	predicted gene, 47953	9108	0.26
chr12_47163286_47163464	3.51	Gm36971	predicted gene, 36971	1667	0.48
chr17_44398035_44398193	3.51	Gm49872	predicted gene, 49872	30211	0.23
chr10_19329521_19329721	3.51	Olig3	oligodendrocyte transcription factor 3	26912	0.17
chr2_28780313_28780498	3.50	Gm13385	predicted gene 13385	13164	0.13
chr7_95991206_95991793	3.49	Gm5037	predicted gene 5037	78113	0.11
chr13_71507941_71508418	3.49	1700112M02Rik	RIKEN cDNA 1700112M02 gene	20572	0.26
chr16_71497335_71497513	3.48	Gm22797	predicted gene, 22797	166364	0.04
chr4_85250379_85250530	3.48	Gm12413	predicted gene 12413	4692	0.28
chrX_9696032_9696343	3.47	Dynlt3	dynein light chain Tctex-type 3	33184	0.19
chr3_141936313_141936536	3.47	Bmpr1b	bone morphogenetic protein receptor, type 1B	4901	0.33
chr8_92167277_92167548	3.45	Gm45335	predicted gene 45335	5175	0.21
chr7_29071400_29071669	3.45	Gm26604	predicted gene, 26604	69	0.87
chr1_5232314_5232482	3.43	Gm7182	predicted gene 7182	44939	0.16
chr2_116324478_116324629	3.42	Gm13991	predicted gene 13991	203937	0.02
chr2_65956896_65957070	3.42	Gm13617	predicted gene 13617	2913	0.28
chr19_25607993_25608244	3.42	Dmrt3	doublesex and mab-3 related transcription factor 3	2183	0.36
chr18_78455374_78455574	3.41	4931439C15Rik	RIKEN cDNA 4931439C15 gene	21404	0.24
chr13_78181182_78181614	3.41	Gm38604	predicted gene, 38604	1761	0.26
chr10_17202862_17203093	3.41	Gm25382	predicted gene, 25382	86173	0.09
chr11_19350855_19351213	3.40	Gm12025	predicted gene 12025	10035	0.25
chr6_141050341_141050632	3.40	Gm43927	predicted gene, 43927	42201	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.7	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.7	9.9	GO:0098596	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
1.5	4.5	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.5	8.7	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.3	3.9	GO:0032289	central nervous system myelin formation(GO:0032289)
1.3	3.9	GO:0060166	olfactory pit development(GO:0060166)
1.3	5.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.2	8.4	GO:0016198	axon choice point recognition(GO:0016198)
1.2	5.8	GO:0016576	histone dephosphorylation(GO:0016576)
1.1	3.4	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
1.1	3.4	GO:0021553	olfactory nerve development(GO:0021553)
1.1	4.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.0	4.9	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.9	1.9	GO:0031223	auditory behavior(GO:0031223)
0.9	3.8	GO:0030035	microspike assembly(GO:0030035)
0.9	2.7	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.9	1.8	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.9	2.6	GO:0021856	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.9	2.6	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.9	3.4	GO:0060594	mammary gland specification(GO:0060594)
0.8	2.5	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.8	8.9	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.8	0.8	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.8	4.8	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.8	3.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.8	2.3	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.7	3.0	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.7	1.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7	2.9	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7	2.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.7	0.7	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.7	2.8	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.7	1.4	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.7	6.2	GO:0071625	vocalization behavior(GO:0071625)
0.6	1.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.6	1.9	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.6	1.3	GO:0061642	chemoattraction of axon(GO:0061642)
0.6	1.9	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.6	1.9	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.6	1.2	GO:0060174	limb bud formation(GO:0060174)
0.6	1.8	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.6	0.6	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.6	0.6	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.6	1.8	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.6	1.8	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6	2.4	GO:0001927	exocyst assembly(GO:0001927)
0.6	1.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.6	4.7	GO:0046069	cGMP catabolic process(GO:0046069)
0.6	2.3	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.6	1.7	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.6	1.7	GO:0072199	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.6	3.4	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.6	5.0	GO:0050957	equilibrioception(GO:0050957)
0.5	0.5	GO:0021756	striatum development(GO:0021756)
0.5	2.7	GO:0003344	pericardium morphogenesis(GO:0003344)
0.5	2.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.5	1.6	GO:1990123	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.5	1.6	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.5	1.6	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5	2.6	GO:0071397	cellular response to cholesterol(GO:0071397)
0.5	2.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.5	1.5	GO:0061743	motor learning(GO:0061743)
0.5	2.5	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.5	1.0	GO:0003358	noradrenergic neuron development(GO:0003358)
0.5	1.5	GO:0060437	lung growth(GO:0060437)
0.5	8.4	GO:0016082	synaptic vesicle priming(GO:0016082)
0.5	1.9	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
0.5	1.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.5	1.4	GO:0035262	gonad morphogenesis(GO:0035262)
0.5	2.8	GO:0035881	amacrine cell differentiation(GO:0035881)
0.5	1.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5	0.9	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5	0.5	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.5	2.3	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.5	3.6	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.4	3.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.4	4.4	GO:0035641	locomotory exploration behavior(GO:0035641)
0.4	1.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4	0.9	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.4	2.2	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4	0.9	GO:0046959	habituation(GO:0046959)
0.4	1.3	GO:0046684	response to pyrethroid(GO:0046684)
0.4	6.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.4	1.7	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.4	1.2	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.4	0.4	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.4	0.8	GO:0007412	axon target recognition(GO:0007412)
0.4	1.6	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4	1.2	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.4	1.2	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4	1.2	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.4	0.8	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.4	1.6	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.4	2.3	GO:0060581	ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.4	0.8	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.4	1.1	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.4	1.9	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.4	4.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4	1.1	GO:0030070	insulin processing(GO:0030070)
0.4	1.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.4	1.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.4	2.8	GO:0002329	pre-B cell differentiation(GO:0002329)
0.3	1.4	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	0.7	GO:0060513	prostatic bud formation(GO:0060513)
0.3	5.9	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.3	0.7	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.3	0.7	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.3	1.0	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.3	1.4	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.3	0.7	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.3	2.3	GO:0001553	luteinization(GO:0001553)
0.3	0.3	GO:0048880	sensory system development(GO:0048880)
0.3	1.3	GO:0016584	nucleosome positioning(GO:0016584)
0.3	7.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3	1.0	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.3	0.7	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.3	2.3	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3	1.3	GO:0023041	neuronal signal transduction(GO:0023041)
0.3	0.6	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3	1.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.3	0.6	GO:0060178	regulation of exocyst localization(GO:0060178)
0.3	1.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.3	0.9	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3	0.9	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.3	0.9	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.3	0.6	GO:2000437	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.3	1.5	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3	1.5	GO:1903887	motile primary cilium assembly(GO:1903887)
0.3	1.2	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.3	1.2	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3	3.7	GO:0016486	peptide hormone processing(GO:0016486)
0.3	1.8	GO:0022605	oogenesis stage(GO:0022605)
0.3	0.9	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	1.8	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.3	0.9	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.3	0.3	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.3	0.6	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.3	2.0	GO:0006108	malate metabolic process(GO:0006108)
0.3	0.8	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3	0.6	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.3	0.6	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.3	2.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.3	1.4	GO:0021871	forebrain regionalization(GO:0021871)
0.3	1.6	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.3	0.8	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.3	2.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.3	0.3	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.3	1.1	GO:0030091	protein repair(GO:0030091)
0.3	0.8	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.3	22.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	1.1	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3	0.8	GO:0021542	dentate gyrus development(GO:0021542)
0.3	1.0	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.3	1.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.3	0.8	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3	1.5	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.2	1.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	1.5	GO:0060179	male mating behavior(GO:0060179)
0.2	1.0	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.2	0.5	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2	0.5	GO:0021559	trigeminal nerve development(GO:0021559)
0.2	1.9	GO:0097120	receptor localization to synapse(GO:0097120)
0.2	2.4	GO:0035418	protein localization to synapse(GO:0035418)
0.2	1.6	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2	0.5	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.2	1.9	GO:0032570	response to progesterone(GO:0032570)
0.2	0.7	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.2	1.2	GO:0048242	epinephrine secretion(GO:0048242)
0.2	1.1	GO:0035989	tendon development(GO:0035989)
0.2	0.5	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.2	0.9	GO:0060155	platelet dense granule organization(GO:0060155)
0.2	1.3	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.2	0.2	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2	0.7	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	0.9	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.2	0.7	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.2	0.4	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.2	0.2	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661)
0.2	0.4	GO:0071435	potassium ion export(GO:0071435)
0.2	0.9	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	0.6	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2	1.9	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2	0.6	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.2	0.6	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2	2.1	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.2	0.8	GO:0035627	ceramide transport(GO:0035627)
0.2	1.2	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.2	0.2	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2	0.4	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.2	GO:0002125	maternal aggressive behavior(GO:0002125)
0.2	0.8	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
0.2	1.0	GO:0015808	L-alanine transport(GO:0015808)
0.2	0.8	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	0.6	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	0.8	GO:0022038	corpus callosum development(GO:0022038)
0.2	0.6	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.2	1.5	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2	0.8	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2	0.8	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.2	0.4	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.2	0.6	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.2	0.6	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.2	0.6	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.2	0.6	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.2	1.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	0.5	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2	0.7	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.2	0.2	GO:0086064	cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.2	0.4	GO:0046103	inosine biosynthetic process(GO:0046103)
0.2	1.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.2	0.7	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2	0.4	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.2	0.5	GO:0097503	sialylation(GO:0097503)
0.2	0.3	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2	1.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2	1.4	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.2	0.3	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	0.2	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.2	0.5	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.2	0.3	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.2	0.5	GO:0051036	regulation of endosome size(GO:0051036)
0.2	1.3	GO:0060736	prostate gland growth(GO:0060736)
0.2	1.4	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.2	0.5	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.2	0.2	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.2	0.5	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	0.6	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	0.2	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.2	1.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.5	GO:0090427	activation of meiosis(GO:0090427)
0.2	0.2	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.2	0.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.2	1.7	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.2	0.5	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	0.3	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.2	0.8	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.2	0.5	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.1	0.6	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.1	0.3	GO:0046098	guanine metabolic process(GO:0046098)
0.1	0.6	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.3	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1	0.4	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1	0.4	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.4	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1	2.0	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.3	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.1	0.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.7	GO:0030578	PML body organization(GO:0030578)
0.1	0.1	GO:1903998	regulation of eating behavior(GO:1903998)
0.1	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.6	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	1.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	1.0	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1	0.1	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	0.1	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1	0.7	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.3	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.7	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.4	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.1	0.3	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.1	0.1	GO:0072092	ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1	0.3	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.1	0.4	GO:0060005	vestibular reflex(GO:0060005)
0.1	0.3	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.3	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1	0.4	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.5	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.1	0.3	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.1	0.7	GO:0019532	oxalate transport(GO:0019532)
0.1	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.7	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	0.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.4	GO:0048478	replication fork protection(GO:0048478)
0.1	0.6	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.1	0.4	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.5	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.5	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1	0.5	GO:0090148	membrane fission(GO:0090148)
0.1	0.2	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.1	0.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.1	GO:0021855	hypothalamus cell migration(GO:0021855)
0.1	0.5	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.6	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.5	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.5	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.1	1.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.1	0.2	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.1	0.2	GO:0014028	notochord formation(GO:0014028)
0.1	0.4	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1	0.2	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.7	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1	0.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.6	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.2	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1	0.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.1	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.7	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.4	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.4	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.1	1.7	GO:1902668	negative regulation of axon guidance(GO:1902668)
0.1	0.2	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.9	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	1.2	GO:0001964	startle response(GO:0001964)
0.1	1.3	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.3	GO:0046208	spermine catabolic process(GO:0046208)
0.1	0.4	GO:0042414	epinephrine metabolic process(GO:0042414)
0.1	0.4	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.1	0.7	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	0.1	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.1	0.3	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.3	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	0.2	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1	0.5	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.1	GO:0045632	negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1	0.7	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.1	1.4	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1	0.9	GO:0001878	response to yeast(GO:0001878)
0.1	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	0.3	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.4	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1	0.3	GO:0006742	NADP catabolic process(GO:0006742)
0.1	0.5	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1	0.2	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	0.2	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1	0.3	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.1	0.5	GO:0072176	nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.1	0.5	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.1	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.2	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.2	GO:0061055	myotome development(GO:0061055)
0.1	0.3	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.5	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.3	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.1	0.4	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1	0.4	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.1	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1	0.5	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.3	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1	0.4	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.3	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1	0.3	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.1	3.5	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	1.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.1	0.2	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.1	0.2	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.2	GO:1902534	single-organism membrane invagination(GO:1902534)
0.1	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.2	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1	0.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	0.3	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.2	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.2	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1	0.4	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.1	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.1	0.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.8	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.2	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	0.4	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	0.2	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.1	0.5	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.4	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.2	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.2	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.1	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.1	0.6	GO:0042428	serotonin metabolic process(GO:0042428)
0.1	0.1	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.1	0.2	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1	0.2	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1	0.2	GO:0031296	B cell costimulation(GO:0031296)
0.1	0.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0002765	immune response-inhibiting signal transduction(GO:0002765)
0.1	0.3	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.3	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	0.2	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.1	0.1	GO:0014029	neural crest formation(GO:0014029)
0.1	0.2	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.1	0.6	GO:0097369	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.2	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1	0.2	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.3	GO:0042473	outer ear morphogenesis(GO:0042473)
0.1	0.3	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	0.2	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.3	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1	0.3	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	0.2	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.1	0.2	GO:0021854	hypothalamus development(GO:0021854)
0.1	0.6	GO:0003356	regulation of cilium beat frequency(GO:0003356)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.4	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.1	0.2	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.2	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1	0.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.1	0.2	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.1	0.3	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	0.3	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.1	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1	0.2	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.1	0.2	GO:0051697	protein delipidation(GO:0051697)
0.1	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.1	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1	0.2	GO:0045054	constitutive secretory pathway(GO:0045054)
0.1	0.2	GO:0002215	defense response to nematode(GO:0002215)
0.1	0.2	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.1	0.6	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.1	0.3	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.2	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	0.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.1	GO:0014848	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.1	0.2	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.2	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.0	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698)
0.0	1.1	GO:0071242	cellular response to ammonium ion(GO:0071242)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859)
0.0	1.0	GO:0021954	central nervous system neuron development(GO:0021954)
0.0	0.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.2	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.1	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0009233	menaquinone metabolic process(GO:0009233)
0.0	1.0	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.2	GO:2000380	regulation of mesoderm development(GO:2000380)
0.0	0.0	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.1	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.2	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.1	GO:1902306	negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0	0.1	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	1.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.2	GO:0072044	collecting duct development(GO:0072044)
0.0	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.0	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0	0.1	GO:0061110	dense core granule biogenesis(GO:0061110)
0.0	0.3	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	1.0	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.2	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:0030540	female genitalia development(GO:0030540)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.1	GO:0072530	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.0	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.9	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.2	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.0	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.0	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.2	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:2000615	regulation of histone H3-K9 acetylation(GO:2000615)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0032824	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0	0.3	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.0	0.0	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.2	GO:0042756	drinking behavior(GO:0042756)
0.0	0.1	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.0	0.2	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.2	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.1	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0045113	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113)
0.0	0.0	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.2	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	1.5	GO:0071804	cellular potassium ion transport(GO:0071804)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.0	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.0	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.0	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.7	GO:0097485	neuron projection guidance(GO:0097485)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.0	GO:0001806	type IV hypersensitivity(GO:0001806)
0.0	0.0	GO:0033750	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
1.1	7.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.8	3.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7	2.8	GO:0033010	paranodal junction(GO:0033010)
0.6	6.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.6	2.9	GO:0097433	dense body(GO:0097433)
0.6	4.6	GO:0043083	synaptic cleft(GO:0043083)
0.6	1.7	GO:1990761	growth cone lamellipodium(GO:1990761)
0.5	7.4	GO:0043196	varicosity(GO:0043196)
0.5	3.2	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5	1.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.5	2.3	GO:0044294	dendritic growth cone(GO:0044294)
0.4	4.5	GO:0043194	axon initial segment(GO:0043194)
0.4	4.0	GO:0035253	ciliary rootlet(GO:0035253)
0.4	0.9	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4	1.3	GO:0072534	perineuronal net(GO:0072534)
0.4	7.1	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4	5.9	GO:0031527	filopodium membrane(GO:0031527)
0.4	2.7	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.4	3.4	GO:0005883	neurofilament(GO:0005883)
0.4	1.5	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.4	1.1	GO:0097441	basilar dendrite(GO:0097441)
0.4	1.8	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.3	7.7	GO:0044295	axonal growth cone(GO:0044295)
0.3	1.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.3	1.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3	0.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.3	2.4	GO:0030673	axolemma(GO:0030673)
0.3	0.9	GO:0048179	activin receptor complex(GO:0048179)
0.3	1.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3	1.7	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.3	2.2	GO:0042788	polysomal ribosome(GO:0042788)
0.3	3.8	GO:0060077	inhibitory synapse(GO:0060077)
0.3	0.8	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	0.8	GO:0005899	insulin receptor complex(GO:0005899)
0.3	11.1	GO:0042734	presynaptic membrane(GO:0042734)
0.2	6.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.2	1.4	GO:0032584	growth cone membrane(GO:0032584)
0.2	6.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.2	0.9	GO:1990716	axonemal central apparatus(GO:1990716)
0.2	1.5	GO:0033263	CORVET complex(GO:0033263)
0.2	1.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.2	0.6	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2	2.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.2	1.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	0.8	GO:0005955	calcineurin complex(GO:0005955)
0.2	1.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	0.6	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2	0.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	0.5	GO:0070939	Dsl1p complex(GO:0070939)
0.2	1.6	GO:0060091	kinocilium(GO:0060091)
0.2	2.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	0.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	2.0	GO:0031045	dense core granule(GO:0031045)
0.1	0.7	GO:0044292	dendrite terminus(GO:0044292)
0.1	1.0	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.5	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	1.3	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.1	0.4	GO:0000802	transverse filament(GO:0000802)
0.1	0.9	GO:0071437	invadopodium(GO:0071437)
0.1	0.9	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.4	GO:0032280	symmetric synapse(GO:0032280)
0.1	0.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.4	GO:0030314	junctional membrane complex(GO:0030314)
0.1	5.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	1.1	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	1.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.6	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	1.2	GO:0071564	npBAF complex(GO:0071564)
0.1	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.6	GO:0030914	STAGA complex(GO:0030914)
0.1	0.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.9	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	0.6	GO:0070187	telosome(GO:0070187)
0.1	0.2	GO:0000814	ESCRT II complex(GO:0000814)
0.1	3.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	0.9	GO:0032433	filopodium tip(GO:0032433)
0.1	1.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.3	GO:0032021	NELF complex(GO:0032021)
0.1	0.8	GO:0033655	host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.1	9.2	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	0.7	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.3	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.7	GO:0042555	MCM complex(GO:0042555)
0.1	3.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	5.8	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.3	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	4.8	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1	0.8	GO:0043205	fibril(GO:0043205)
0.1	0.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.1	GO:0044393	microspike(GO:0044393)
0.1	0.2	GO:0043511	inhibin complex(GO:0043511)
0.0	0.6	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.4	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.7	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	1.2	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	2.8	GO:0043204	perikaryon(GO:0043204)
0.0	0.4	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	1.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.4	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.2	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	1.1	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.2	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	0.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0055087	Ski complex(GO:0055087)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	17.0	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
3.0	9.0	GO:0070699	type II activin receptor binding(GO:0070699)
1.6	4.9	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.1	3.3	GO:0097109	neuroligin family protein binding(GO:0097109)
1.0	4.9	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.9	3.5	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.9	2.6	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.9	2.6	GO:0050816	phosphothreonine binding(GO:0050816)
0.9	2.6	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.8	3.3	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.7	5.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.7	5.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6	5.7	GO:0038191	neuropilin binding(GO:0038191)
0.6	1.9	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6	3.7	GO:0004385	guanylate kinase activity(GO:0004385)
0.6	1.8	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.6	2.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6	2.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6	4.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5	1.6	GO:0005148	prolactin receptor binding(GO:0005148)
0.5	2.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.5	2.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.5	0.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5	2.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.5	0.5	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4	1.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.4	2.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4	1.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.4	2.5	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.4	4.6	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4	1.6	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4	1.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.4	1.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.4	0.8	GO:0016361	activin receptor activity, type I(GO:0016361)
0.4	2.8	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.4	5.0	GO:0050811	GABA receptor binding(GO:0050811)
0.4	3.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.4	1.5	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.4	1.9	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	2.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.4	1.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.4	1.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.3	4.9	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.3	1.7	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3	0.6	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.3	1.3	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	1.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3	3.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.3	6.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	0.9	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	1.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3	1.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	1.5	GO:0004565	beta-galactosidase activity(GO:0004565)
0.3	0.9	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.3	0.8	GO:0097108	hedgehog family protein binding(GO:0097108)
0.3	1.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	2.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	0.5	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3	0.8	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3	1.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.2	5.2	GO:0071837	HMG box domain binding(GO:0071837)
0.2	1.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2	0.5	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2	4.1	GO:0045499	chemorepellent activity(GO:0045499)
0.2	4.7	GO:0017075	syntaxin-1 binding(GO:0017075)
0.2	0.9	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.2	1.1	GO:0004985	opioid receptor activity(GO:0004985)
0.2	0.9	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	2.0	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.2	0.4	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.2	1.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	2.4	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	0.2	GO:0017002	activin-activated receptor activity(GO:0017002)
0.2	0.8	GO:0008502	melatonin receptor activity(GO:0008502)
0.2	4.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	0.8	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.2	1.7	GO:0002162	dystroglycan binding(GO:0002162)
0.2	1.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2	0.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	0.4	GO:0045503	dynein light chain binding(GO:0045503)
0.2	1.7	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.2	0.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	0.4	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.2	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	0.7	GO:0005042	netrin receptor activity(GO:0005042)
0.2	0.5	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.2	0.9	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.2	0.7	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2	1.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2	0.9	GO:0030957	Tat protein binding(GO:0030957)
0.2	0.9	GO:0031419	cobalamin binding(GO:0031419)
0.2	0.5	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.2	1.0	GO:0016421	CoA carboxylase activity(GO:0016421)
0.2	1.5	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.2	0.5	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.2	0.8	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.2	1.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	0.5	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2	3.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	1.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.2	0.8	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.2	0.8	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	0.5	GO:0070052	collagen V binding(GO:0070052)
0.1	3.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	0.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	1.9	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	0.3	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.6	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1	1.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	1.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.1	1.2	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1	0.9	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.7	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.1	0.5	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.5	GO:0043842	Kdo transferase activity(GO:0043842)
0.1	0.6	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.0	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	1.8	GO:0031402	sodium ion binding(GO:0031402)
0.1	1.7	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.6	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.5	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.4	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	1.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.5	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1	0.2	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.5	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	1.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	1.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.6	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.5	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.4	GO:0000403	Y-form DNA binding(GO:0000403)
0.1	0.8	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.4	GO:0097001	ceramide binding(GO:0097001)
0.1	0.5	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.3	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.3	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	1.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	1.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1	0.4	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.1	1.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.4	GO:0070728	leucine binding(GO:0070728)
0.1	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	2.1	GO:0005272	sodium channel activity(GO:0005272)
0.1	0.4	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.2	GO:0016015	morphogen activity(GO:0016015)
0.1	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.1	2.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	0.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.7	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.1	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.1	0.2	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.8	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.1	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	1.5	GO:0052712	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1	2.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.1	0.8	GO:0035198	miRNA binding(GO:0035198)
0.1	0.2	GO:0070878	primary miRNA binding(GO:0070878)
0.1	0.5	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.1	0.1	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1	0.4	GO:0046790	virion binding(GO:0046790)
0.1	0.1	GO:0001030	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.7	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	1.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	0.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.3	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.1	1.1	GO:0005537	mannose binding(GO:0005537)
0.1	0.3	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.4	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.2	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.5	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.5	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	1.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.0	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.3	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	1.0	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	1.0	GO:0005109	frizzled binding(GO:0005109)
0.0	0.6	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0016019	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0	0.0	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.4	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.3	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	1.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.1	GO:0019002	GMP binding(GO:0019002)
0.0	0.0	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	1.2	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0070694	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0000009	alpha-1,6-mannosyltransferase activity(GO:0000009)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.0	GO:0019187	beta-1,4-mannosyltransferase activity(GO:0019187)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	1.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.8	2.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.4	0.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3	3.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.3	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.3	9.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	5.0	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	1.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	1.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	2.8	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	ST ADRENERGIC	Adrenergic Pathway
0.0	0.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.5	7.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	6.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4	4.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.4	7.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.3	8.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	0.3	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.3	5.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	2.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.3	2.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3	2.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	3.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	9.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.2	1.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	4.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	0.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.2	1.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2	1.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.2	3.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	3.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	2.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	2.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	1.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	0.3	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.1	3.9	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	1.0	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	0.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.9	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	0.8	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	1.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	0.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	2.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.7	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	2.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.9	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	0.9	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	0.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.6	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.8	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.0	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus

Results for Nkx2-3

Z-value: 2.23

Motif logo

Transcription factors associated with Nkx2-3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nkx2-3 motif across conditions

Conditions sorted by the z-value of the Nkx2-3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: