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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nkx2-6

Z-value: 1.33

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Transcription factors associated with Nkx2-6

Gene Symbol	Gene ID	Gene Info
Nkx2-6 Ensembl NCBI MGI UniProt	ENSMUSG00000044186.9	NK2 homeobox 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nkx2-6	mm10_chr14_69135966_69136117	0.56	8.4e-06	Click!

Activity of the Nkx2-6 motif across conditions

Conditions sorted by the z-value of the Nkx2-6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_97076076_97076280	5.94	4930573H18Rik	RIKEN cDNA 4930573H18 gene	16607	0.15
chr2_128850140_128850291	5.83	Tmem87b	transmembrane protein 87B	255	0.9
chr3_98410923_98411117	5.75	Zfp697	zinc finger protein 697	28472	0.12
chr15_63065959_63066540	5.59	Gm30159	predicted gene, 30159	74158	0.1
chr11_88555646_88556084	5.54	Msi2	musashi RNA-binding protein 2	34282	0.19
chr9_111056507_111056723	5.48	Ccrl2	chemokine (C-C motif) receptor-like 2	631	0.55
chr5_122602364_122602555	5.34	Ift81	intraflagellar transport 81	1034	0.42
chr9_67163871_67164040	5.29	Gm19299	predicted gene, 19299	30394	0.15
chr9_69459008_69459311	5.11	Mir3109	microRNA 3109	2215	0.19
chr5_127282655_127282806	4.89	Tmem132cos	transmembrane protein 132C, opposite strand	1096	0.53
chr17_70979455_70979649	4.87	Myl12b	myosin, light chain 12B, regulatory	1020	0.36
chr10_117987340_117987491	4.81	Gm37852	predicted gene, 37852	17523	0.19
chr4_57592877_57593028	4.81	Pakap	paralemmin A kinase anchor protein	24622	0.23
chr8_126833325_126834152	4.73	A630001O12Rik	RIKEN cDNA A630001O12 gene	5495	0.23
chr16_57569043_57569375	4.58	Filip1l	filamin A interacting protein 1-like	19967	0.21
chr15_3433353_3433783	4.46	Ghr	growth hormone receptor	38076	0.2
chr9_56260137_56260407	4.43	Peak1os	pseudopodium-enriched atypical kinase 1, opposite strand	2382	0.2
chr2_166196495_166196648	4.36	Gm11466	predicted gene 11466	5709	0.17
chr8_33905789_33906327	4.34	Rbpms	RNA binding protein gene with multiple splicing	14294	0.16
chr12_8099252_8099403	4.33	Apob	apolipoprotein B	86968	0.08
chr1_52251069_52251220	4.25	Gls	glutaminase	17912	0.19
chr1_150984135_150984286	4.14	Hmcn1	hemicentin 1	8841	0.19
chr16_25011199_25011350	4.06	A230028O05Rik	RIKEN cDNA A230028O05 gene	48365	0.18
chr7_112268723_112268946	4.04	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	2465	0.41
chr7_126636753_126636921	3.99	Nupr1	nuclear protein transcription regulator 1	5976	0.08
chr5_73358879_73359363	3.98	Ociad2	OCIA domain containing 2	18093	0.11
chr13_104636008_104636486	3.98	2610204G07Rik	RIKEN cDNA 2610204G07 gene	48684	0.17
chr7_16583787_16584087	3.94	Gm29443	predicted gene 29443	29887	0.08
chr17_26864441_26864592	3.93	Gm20468	predicted gene 20468	3095	0.13
chr4_83206835_83207691	3.87	Gm11185	predicted gene 11185	13275	0.19
chr17_78791500_78791895	3.81	Heatr5b	HEAT repeat containing 5B	4416	0.16
chr2_164449524_164449675	3.78	Sdc4	syndecan 4	5712	0.09
chr1_185311896_185312216	3.76	2010103J01Rik	RIKEN cDNA 2010103J01 gene	131	0.88
chrX_72761638_72761789	3.76	Gabrq	gamma-aminobutyric acid (GABA) A receptor, subunit theta	63465	0.09
chr7_115466804_115467141	3.75	Sox6	SRY (sex determining region Y)-box 6	130924	0.05
chr2_142641897_142642048	3.68	Kif16b	kinesin family member 16B	6791	0.27
chr8_122036418_122036587	3.50	Banp	BTG3 associated nuclear protein	35655	0.12
chr11_55405684_55405936	3.35	Sparc	secreted acidic cysteine rich glycoprotein	3645	0.2
chr4_139432894_139433045	3.29	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	2041	0.29
chr5_43981740_43981912	3.28	Fgfbp1	fibroblast growth factor binding protein 1	47	0.96
chr15_85347412_85347563	3.25	Gm23517	predicted gene, 23517	3767	0.24
chr16_23498930_23499285	3.21	Gm49514	predicted gene, 49514	15163	0.14
chr4_142221224_142221954	3.18	Kazn	kazrin, periplakin interacting protein	11383	0.22
chr16_4978726_4978909	3.17	4930451G09Rik	RIKEN cDNA 4930451G09 gene	12562	0.09
chr10_25432432_25432611	3.11	Epb41l2	erythrocyte membrane protein band 4.1 like 2	78	0.97
chr9_62775485_62775741	3.00	Gm7653	predicted gene 7653	14291	0.17
chr10_117042006_117042172	2.98	Gm10747	predicted gene 10747	1657	0.26
chr4_155780948_155781191	2.94	Tmem88b	transmembrane protein 88B	4805	0.07
chr6_53509175_53509326	2.89	Creb5	cAMP responsive element binding protein 5	64050	0.12
chr6_92468381_92468552	2.84	Prickle2	prickle planar cell polarity protein 2	12926	0.26
chr8_70631552_70631912	2.75	Gdf15	growth differentiation factor 15	363	0.72
chr5_34217838_34218173	2.73	Gm42848	predicted gene 42848	3157	0.14
chr3_95695418_95695636	2.72	Adamtsl4	ADAMTS-like 4	7610	0.11
chr4_97752084_97752245	2.69	Gm12676	predicted gene 12676	5225	0.23
chr4_32890040_32890622	2.66	Gm11941	predicted gene 11941	2355	0.28
chr5_146846682_146846833	2.64	Rasl11a	RAS-like, family 11, member A	992	0.43
chr14_28010907_28011197	2.60	Erc2	ELKS/RAB6-interacting/CAST family member 2	35376	0.23
chr9_9165529_9165680	2.60	Gm16833	predicted gene, 16833	70684	0.11
chr18_13560776_13561017	2.59	AC103362.1	novel transcript	40504	0.21
chr11_109343659_109343810	2.57	1700096J18Rik	RIKEN cDNA 1700096J18 gene	3105	0.19
chr10_116267458_116267676	2.56	Ptprb	protein tyrosine phosphatase, receptor type, B	7956	0.2
chr2_32455207_32455358	2.55	Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	3837	0.12
chr3_137940725_137941098	2.51	Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	13802	0.09
chr3_97072490_97072737	2.51	4930573H18Rik	RIKEN cDNA 4930573H18 gene	20172	0.14
chr2_20909530_20909690	2.51	Arhgap21	Rho GTPase activating protein 21	5084	0.23
chr12_32995560_32995750	2.49	Gm24922	predicted gene, 24922	4355	0.17
chr2_35496015_35496166	2.44	Gm13445	predicted gene 13445	4571	0.15
chr4_65813555_65813735	2.42	Trim32	tripartite motif-containing 32	208396	0.03
chr9_71663389_71664022	2.39	Cgnl1	cingulin-like 1	15355	0.21
chr6_122702513_122702906	2.37	Gm10224	predicted pseudogene 10224	3681	0.14
chr5_77129945_77130248	2.35	Gm15831	predicted gene 15831	7748	0.13
chr17_47957975_47958336	2.35	Gm5228	predicted gene 5228	22065	0.12
chr3_79726744_79726895	2.30	Rxfp1	relaxin/insulin-like family peptide receptor 1	10975	0.19
chr4_134156862_134157025	2.29	Cep85	centrosomal protein 85	22	0.95
chr3_27503428_27503579	2.28	Gm43344	predicted gene 43344	43138	0.17
chr16_18705131_18705282	2.26	Rps2-ps7	ribosomal protein S2, pseudogene 7	22990	0.14
chr6_94710006_94710162	2.23	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	9926	0.23
chr17_44213343_44213499	2.21	Clic5	chloride intracellular channel 5	23685	0.24
chr11_72428738_72428932	2.20	Ggt6	gamma-glutamyltransferase 6	6691	0.13
chr9_59684059_59684343	2.20	Gramd2	GRAM domain containing 2	4057	0.16
chr16_21818710_21818992	2.19	Map3k13	mitogen-activated protein kinase kinase kinase 13	7091	0.12
chr13_56634717_56634868	2.19	Tgfbi	transforming growth factor, beta induced	3579	0.25
chr2_35582270_35582457	2.19	Dab2ip	disabled 2 interacting protein	477	0.81
chr1_151236148_151236299	2.18	Gm24402	predicted gene, 24402	24691	0.11
chr2_125667173_125667345	2.15	Eid1	EP300 interacting inhibitor of differentiation 1	5836	0.2
chr7_65388709_65388861	2.15	Gm44795	predicted gene 44795	13062	0.18
chr2_166514481_166514632	2.14	Gm14267	predicted gene 14267	1810	0.4
chr15_97004302_97004609	2.13	Slc38a4	solute carrier family 38, member 4	15496	0.26
chr13_45960285_45960579	2.12	Atxn1	ataxin 1	4525	0.21
chr18_21255157_21255390	2.11	Garem1	GRB2 associated regulator of MAPK1 subtype 1	44850	0.13
chr16_91406926_91407165	2.11	Il10rb	interleukin 10 receptor, beta	601	0.6
chr13_36097100_36097272	2.10	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	20226	0.16
chr14_57753296_57753601	2.10	Lats2	large tumor suppressor 2	4940	0.14
chr7_80445219_80445911	2.09	Blm	Bloom syndrome, RecQ like helicase	11807	0.12
chr1_60824662_60824820	2.07	Gm11581	predicted gene 11581	15625	0.12
chr10_79988772_79989315	2.07	Cnn2	calponin 2	420	0.61
chr4_120612775_120612947	2.07	Gm12860	predicted gene 12860	2979	0.2
chr19_5827433_5827790	2.05	Neat1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	401	0.66
chr8_79068249_79068400	2.01	Zfp827	zinc finger protein 827	39737	0.15
chr3_126737260_126737412	2.01	Gm42515	predicted gene 42515	161	0.94
chr5_12127914_12128278	1.95	Gm42910	predicted gene 42910	16865	0.19
chr5_99339717_99339868	1.93	Gm35394	predicted gene, 35394	65697	0.12
chr16_23058582_23058733	1.92	Kng1	kininogen 1	264	0.79
chr3_69808597_69808748	1.92	Sptssb	serine palmitoyltransferase, small subunit B	51250	0.12
chr3_51408404_51409520	1.91	Ndufc1	NADH:ubiquinone oxidoreductase subunit C1	2	0.95
chr8_34397835_34398401	1.89	Gm33831	predicted gene, 33831	12290	0.16
chr9_121345573_121345775	1.88	Gm47092	predicted gene, 47092	882	0.55
chr1_77213582_77213738	1.88	Gm38265	predicted gene, 38265	66668	0.12
chr17_71120731_71120895	1.86	Myom1	myomesin 1	91	0.96
chr4_45966218_45966369	1.86	Tdrd7	tudor domain containing 7	959	0.59
chr10_33092534_33092685	1.85	Trdn	triadin	9048	0.26
chr17_24633284_24633465	1.84	Nthl1	nth (endonuclease III)-like 1 (E.coli)	655	0.34
chr14_31408809_31409022	1.84	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	1530	0.33
chr16_30259470_30259621	1.83	Gm49645	predicted gene, 49645	4393	0.16
chr13_99323745_99323902	1.80	Ptcd2	pentatricopeptide repeat domain 2	20882	0.18
chr17_42900854_42901005	1.75	Cd2ap	CD2-associated protein	24264	0.24
chr12_91963291_91963442	1.75	Gm21614	predicted gene, 21614	6211	0.2
chr1_54829957_54830108	1.74	Ankrd44	ankyrin repeat domain 44	16589	0.2
chr14_16558154_16558318	1.72	Rarb	retinoic acid receptor, beta	16809	0.21
chr19_54072365_54072516	1.71	Gm50186	predicted gene, 50186	12119	0.19
chr7_122020256_122021011	1.71	Gga2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	534	0.7
chr8_40905669_40905866	1.71	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	7329	0.17
chr5_145648340_145648491	1.70	Cyp3a63-ps	cytochrome P450, family 3, subfamily a, member 63, pseudogene	14422	0.15
chr9_47529664_47530419	1.68	Cadm1	cell adhesion molecule 1	132	0.96
chr14_32509476_32509771	1.67	Ercc6	excision repair cross-complementing rodent repair deficiency, complementation group 6	3898	0.2
chr18_61331814_61332067	1.67	Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	56917	0.08
chr17_26511994_26512145	1.65	Dusp1	dual specificity phosphatase 1	3550	0.13
chr2_34526490_34527362	1.65	Gm13408	predicted gene 13408	38073	0.15
chr5_77126733_77126884	1.65	Gm15831	predicted gene 15831	4460	0.15
chr13_16715662_16715820	1.64	Gm7537	predicted gene 7537	76251	0.11
chr2_50419752_50419903	1.64	Gm13486	predicted gene 13486	10495	0.22
chr16_22542946_22543153	1.63	Gm49565	predicted gene, 49565	2576	0.17
chr8_85386352_85386514	1.61	Mylk3	myosin light chain kinase 3	88	0.96
chr5_114146874_114147025	1.61	Acacb	acetyl-Coenzyme A carboxylase beta	414	0.75
chr15_93744240_93744451	1.60	Gm30339	predicted gene, 30339	9932	0.21
chr6_51333845_51334059	1.59	Gm6559	predicted gene 6559	45758	0.12
chr12_55446416_55447473	1.59	Psma6	proteasome subunit alpha 6	39561	0.11
chr11_96969209_96969687	1.59	Sp2	Sp2 transcription factor	783	0.43
chr10_70166527_70166678	1.58	Ccdc6	coiled-coil domain containing 6	7907	0.23
chr19_9027902_9028237	1.54	Ahnak	AHNAK nucleoprotein (desmoyokin)	28409	0.09
chr11_86603943_86604094	1.54	Vmp1	vacuole membrane protein 1	1723	0.3
chr7_121075217_121075402	1.53	Mettl9	methyltransferase like 9	22	0.92
chr14_57035004_57035538	1.53	B020004C17Rik	RIKEN cDNA B020004C17 gene	20137	0.15
chr12_73408241_73408392	1.52	D830013O20Rik	RIKEN cDNA D830013O20 gene	1241	0.44
chr5_134644858_134645082	1.48	Eif4h	eukaryotic translation initiation factor 4H	5480	0.13
chr5_31931244_31931395	1.47	Gm43811	predicted gene 43811	4622	0.27
chr13_28738828_28739005	1.47	Mir6368	microRNA 6368	28043	0.21
chr14_62878156_62878444	1.46	n-R5s47	nuclear encoded rRNA 5S 47	8586	0.14
chr11_98874014_98874222	1.44	Gm23640	predicted gene, 23640	3619	0.13
chr17_35917836_35918372	1.44	Mir1894	microRNA 1894	215	0.72
chr1_168502263_168502495	1.41	Mir6348	microRNA 6348	11736	0.27
chr16_18594050_18594201	1.41	4930588K23Rik	RIKEN cDNA 4930588K23 gene	2133	0.2
chr5_144248241_144248469	1.41	2900089D17Rik	RIKEN cDNA 2900089D17 gene	1849	0.23
chr3_68508629_68508947	1.40	Schip1	schwannomin interacting protein 1	14580	0.22
chr17_45987935_45988089	1.40	Gm49805	predicted gene, 49805	26153	0.14
chr15_99084260_99084606	1.39	Troap	trophinin associated protein	1601	0.18
chr6_30528830_30529010	1.38	Cpa2	carboxypeptidase A2, pancreatic	12662	0.12
chr10_60269559_60269710	1.38	Psap	prosaposin	7993	0.19
chr4_117835051_117836181	1.36	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	178	0.91
chr4_149327381_149327548	1.36	Ube4b	ubiquitination factor E4B	4368	0.14
chrX_52372264_52372415	1.35	Mir6384	microRNA 6384	5842	0.25
chr8_36714054_36714221	1.34	Dlc1	deleted in liver cancer 1	18917	0.27
chr4_116894849_116895006	1.34	Gm26355	predicted gene, 26355	9710	0.09
chr4_89445910_89446091	1.33	Gm12608	predicted gene 12608	1356	0.46
chr13_14088703_14089136	1.32	Gm26129	predicted gene, 26129	1480	0.31
chr5_136394928_136395103	1.32	Mir721	microRNA 721	19212	0.16
chr12_17440410_17440594	1.32	Gm36752	predicted gene, 36752	3884	0.24
chr13_81352350_81352692	1.32	Adgrv1	adhesion G protein-coupled receptor V1	895	0.71
chr13_119613872_119614873	1.31	Gm48265	predicted gene, 48265	900	0.48
chr2_9970678_9970952	1.31	Taf3	TATA-box binding protein associated factor 3	17158	0.14
chr13_52037283_52037591	1.30	Gm37872	predicted gene, 37872	15510	0.21
chr7_107755997_107756148	1.30	Cyb5r2	cytochrome b5 reductase 2	1924	0.22
chr3_89113073_89113337	1.29	Gm29704	predicted gene, 29704	3519	0.09
chr4_136138962_136139113	1.28	Gm26001	predicted gene, 26001	1541	0.29
chr11_97682543_97682929	1.28	Cisd3	CDGSH iron sulfur domain 3	3090	0.1
chr7_142459385_142459826	1.27	Lsp1	lymphocyte specific 1	1204	0.3
chr2_36172438_36172589	1.27	Mrrf	mitochondrial ribosome recycling factor	25410	0.1
chr12_77151612_77151767	1.27	Gm22696	predicted gene, 22696	35257	0.17
chr8_36159018_36159251	1.27	Gm38414	predicted gene, 38414	345	0.85
chr8_26352467_26353019	1.26	Gm31784	predicted gene, 31784	40409	0.11
chr5_88711650_88711977	1.26	Mob1b	MOB kinase activator 1B	9042	0.16
chr13_56112615_56112776	1.25	Macroh2a1	macroH2A.1 histone	22130	0.16
chr3_132831269_132831452	1.25	Gm9403	predicted gene 9403	11036	0.14
chr1_153278361_153278512	1.25	Gm38009	predicted gene, 38009	8754	0.18
chr1_91058255_91058406	1.24	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	4744	0.23
chr8_10501879_10502030	1.23	5330413D20Rik	RIKEN cDNA 5330413D20 gene	174959	0.03
chr11_79710875_79711409	1.23	Mir193a	microRNA 193a	827	0.5
chr18_44473059_44473270	1.23	Mcc	mutated in colorectal cancers	46352	0.16
chr9_106345236_106345430	1.23	Gm29123	predicted gene 29123	9500	0.12
chr1_190106720_190107128	1.23	Gm28172	predicted gene 28172	61746	0.11
chr19_45787512_45787663	1.22	Oga	O-GlcNAcase	3750	0.17
chr17_26382840_26382991	1.21	Neurl1b	neuralized E3 ubiquitin protein ligase 1B	31914	0.11
chr2_145822470_145822698	1.21	Rin2	Ras and Rab interactor 2	295	0.92
chr6_30300388_30301283	1.20	Ube2h	ubiquitin-conjugating enzyme E2H	3687	0.18
chr11_78986846_78986997	1.19	Lgals9	lectin, galactose binding, soluble 9	1975	0.31
chr3_38254908_38255074	1.19	Gm2965	predicted gene 2965	31540	0.17
chr5_28055448_28055803	1.19	Gm26608	predicted gene, 26608	166	0.94
chr13_96387644_96388785	1.18	Poc5	POC5 centriolar protein	80	0.97
chr13_30031781_30032211	1.18	Gm11368	predicted gene 11368	26681	0.16
chr1_156667254_156667741	1.17	Tor3a	torsin family 3, member A	767	0.6

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-6

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.7	2.1	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.5	1.6	GO:0009826	unidimensional cell growth(GO:0009826)
0.5	1.6	GO:0048769	sarcomerogenesis(GO:0048769)
0.5	3.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5	2.3	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.3	2.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3	0.8	GO:0006543	glutamine catabolic process(GO:0006543)
0.3	0.8	GO:0086017	Purkinje myocyte action potential(GO:0086017)
0.3	0.8	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.3	1.3	GO:0036233	glycine import(GO:0036233)
0.2	1.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2	0.7	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2	0.7	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.2	0.9	GO:0006549	isoleucine metabolic process(GO:0006549)
0.2	0.2	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.2	1.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.2	0.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	0.9	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	0.5	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	0.9	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	0.5	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.2	0.7	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.5	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.2	0.5	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.5	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.4	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.6	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1	1.6	GO:0030575	nuclear body organization(GO:0030575)
0.1	0.4	GO:0060618	nipple development(GO:0060618)
0.1	0.4	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1	0.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	2.5	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	0.6	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	0.4	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.1	0.6	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.4	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.1	0.5	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1	0.4	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.3	GO:0016095	polyprenol catabolic process(GO:0016095)
0.1	1.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.1	0.6	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.1	0.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	1.0	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.1	0.2	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.1	1.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.1	0.2	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.5	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	0.3	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.1	0.3	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.5	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.4	GO:0015819	lysine transport(GO:0015819)
0.1	0.4	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	2.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	0.3	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	0.3	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	1.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.1	GO:0048382	mesendoderm development(GO:0048382)
0.1	0.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1	0.3	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.3	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	0.3	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.5	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	1.3	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.2	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.1	0.5	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.2	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.1	0.3	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.1	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.1	0.2	GO:0006059	hexitol metabolic process(GO:0006059)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.3	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.1	0.4	GO:0051610	serotonin uptake(GO:0051610)
0.1	0.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.2	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.3	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.3	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.1	0.8	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.4	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.4	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.1	GO:0003383	apical constriction(GO:0003383)
0.1	0.5	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.1	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	1.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.1	GO:0021559	trigeminal nerve development(GO:0021559)
0.1	0.1	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.5	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	0.1	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0050955	thermoception(GO:0050955)
0.1	0.4	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.2	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1	0.3	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.2	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1	0.7	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1	0.3	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.3	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	0.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	0.4	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.4	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1	0.6	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.1	0.2	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	1.0	GO:0030488	tRNA methylation(GO:0030488)
0.1	1.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.3	GO:0006824	cobalt ion transport(GO:0006824)
0.1	0.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1	0.5	GO:1902287	semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1	0.8	GO:0015858	nucleoside transport(GO:0015858)
0.1	0.2	GO:2000065	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.3	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	0.1	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.3	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.3	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.8	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:1904659	glucose transmembrane transport(GO:1904659)
0.0	0.2	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.5	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.2	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.6	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.3	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.2	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.1	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.1	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.1	GO:0090071	regulation of ribosome biogenesis(GO:0090069) negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.1	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.0	0.1	GO:0044598	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.8	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.6	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.2	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.2	GO:1901525	negative regulation of macromitophagy(GO:1901525) negative regulation of mitophagy(GO:1903147)
0.0	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.1	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0	0.1	GO:0007228	signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.2	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.3	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.2	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.5	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.3	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.9	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0044854	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0	0.1	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.1	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.2	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.7	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.2	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.3	GO:2000194	regulation of female gonad development(GO:2000194)
0.0	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	1.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.1	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.2	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.3	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.2	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.1	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.1	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0022009	central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0060375	mast cell differentiation(GO:0060374) regulation of mast cell differentiation(GO:0060375)
0.0	0.0	GO:0045168	cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.7	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0060100	positive regulation of phagocytosis, engulfment(GO:0060100) positive regulation of membrane invagination(GO:1905155)
0.0	0.1	GO:0051126	negative regulation of actin nucleation(GO:0051126)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0021825	substrate-dependent cerebral cortex tangential migration(GO:0021825)
0.0	0.1	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	1.2	GO:0042311	vasodilation(GO:0042311)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.0	0.1	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.1	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
0.0	0.1	GO:2000489	regulation of hepatic stellate cell activation(GO:2000489)
0.0	0.7	GO:1901998	toxin transport(GO:1901998)
0.0	0.2	GO:0046037	GMP metabolic process(GO:0046037)
0.0	1.1	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.4	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0046083	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.5	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.5	GO:0035065	regulation of histone acetylation(GO:0035065)
0.0	0.1	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.6	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.1	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.2	GO:0036336	dendritic cell migration(GO:0036336)
0.0	0.0	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.1	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.0	GO:0002730	dendritic cell cytokine production(GO:0002371) regulation of dendritic cell cytokine production(GO:0002730)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	2.2	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	0.1	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.2	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.5	GO:2000279	negative regulation of DNA biosynthetic process(GO:2000279)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.4	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.3	GO:0045974	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.0	GO:0046607	positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	1.0	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.0	0.0	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.1	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.2	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.0	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.0	0.1	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	1.9	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:1901660	calcium ion export(GO:1901660)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	0.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.2	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.0	GO:0060379	cardiac muscle cell myoblast differentiation(GO:0060379)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:1901679	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.2	GO:0090077	foam cell differentiation(GO:0090077)
0.0	0.5	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.0	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.0	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.1	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.1	GO:0006241	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0	0.1	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0042473	outer ear morphogenesis(GO:0042473)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.3	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.0	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.0	GO:0031052	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.0	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0	0.3	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0051459	regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.2	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.3	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.3	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.1	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0007614	short-term memory(GO:0007614)
0.0	0.1	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.0	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.0	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0	0.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
0.0	0.0	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.4	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:1903751	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.1	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.0	0.0	GO:0007512	adult heart development(GO:0007512)
0.0	0.2	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.1	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:1900048	positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0	0.0	GO:0060066	oviduct development(GO:0060066)
0.0	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0042503	tyrosine phosphorylation of Stat3 protein(GO:0042503) regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0	0.1	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.2	GO:1900003	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.3	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.2	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0	0.2	GO:0098781	ncRNA transcription(GO:0098781)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.0	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.1	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0071549	response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.0	GO:0022615	protein to membrane docking(GO:0022615)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0030878	thyroid gland development(GO:0030878)
0.0	0.0	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:1902742	apoptotic process involved in development(GO:1902742)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.2	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.3	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.0	GO:0046102	inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0	0.0	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.3	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.2	0.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.9	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.2	1.4	GO:0042382	paraspeckles(GO:0042382)
0.2	1.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.2	0.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	0.6	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	2.1	GO:0031430	M band(GO:0031430)
0.1	1.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	1.9	GO:0016460	myosin II complex(GO:0016460)
0.1	0.5	GO:0070545	PeBoW complex(GO:0070545)
0.1	1.4	GO:0070852	cell body fiber(GO:0070852)
0.1	2.3	GO:0000242	pericentriolar material(GO:0000242)
0.1	2.1	GO:0097225	sperm midpiece(GO:0097225)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.6	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.3	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.1	0.3	GO:0035363	histone locus body(GO:0035363)
0.1	1.1	GO:0033391	chromatoid body(GO:0033391)
0.1	2.4	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.2	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	1.4	GO:0005922	connexon complex(GO:0005922)
0.1	0.5	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	2.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.9	GO:0000145	exocyst(GO:0000145)
0.1	0.4	GO:0005916	fascia adherens(GO:0005916)
0.1	0.5	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	2.1	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.6	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	0.2	GO:0071953	elastic fiber(GO:0071953)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.5	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.8	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	1.0	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.5	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.6	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.3	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	1.5	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.6	GO:0051233	spindle midzone(GO:0051233)
0.0	0.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	1.2	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	1.7	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0036379	myofilament(GO:0036379)
0.0	0.0	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.5	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0000922	spindle pole(GO:0000922)
0.0	0.0	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.3	GO:0072562	blood microparticle(GO:0072562)
0.0	0.1	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.7	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0033269	internode region of axon(GO:0033269)
0.0	0.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	1.1	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	2.1	GO:0000139	Golgi membrane(GO:0000139)
0.0	0.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.3	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.3	GO:0000791	euchromatin(GO:0000791)
0.0	0.0	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.8	GO:0030017	sarcomere(GO:0030017)
0.0	0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.4	GO:0005844	polysome(GO:0005844)
0.0	0.4	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.5	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0043203	axon hillock(GO:0043203)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.1	GO:0042731	PH domain binding(GO:0042731)
0.6	1.8	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.5	1.4	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.4	2.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.4	1.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.3	1.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3	1.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.3	1.2	GO:0009374	biotin binding(GO:0009374)
0.3	0.8	GO:0004359	glutaminase activity(GO:0004359)
0.2	1.6	GO:0018639	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.2	3.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	1.1	GO:0030274	LIM domain binding(GO:0030274)
0.2	1.8	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	0.7	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	1.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.2	0.8	GO:0071253	connexin binding(GO:0071253)
0.2	1.0	GO:0018499	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.1	0.7	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	3.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.3	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.3	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.3	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1	0.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	1.9	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.6	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	0.6	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.6	GO:0016936	galactoside binding(GO:0016936)
0.1	0.5	GO:0051525	NFAT protein binding(GO:0051525)
0.1	1.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.6	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.3	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.4	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1	0.3	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.2	GO:0004096	catalase activity(GO:0004096)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.3	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.1	0.3	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1	0.2	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	1.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	0.8	GO:0008143	poly(A) binding(GO:0008143)
0.1	0.6	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.1	0.7	GO:0017065	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1	0.2	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	0.8	GO:0008418	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1	0.8	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.1	0.3	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.1	0.2	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.8	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.2	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0004337	geranyltranstransferase activity(GO:0004337)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.7	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.2	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.3	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.2	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	2.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.4	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.4	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	1.9	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.4	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.3	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.5	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.5	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	1.1	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	1.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0001884	pyrimidine nucleoside binding(GO:0001884)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	1.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.4	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.3	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0052835	cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.4	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.4	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	1.9	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	2.2	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.0	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.0	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.8	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	2.6	GO:0005516	calmodulin binding(GO:0005516)
0.0	0.1	GO:0044213	intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.8	GO:0017022	myosin binding(GO:0017022)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	1.4	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	1.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.7	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.8	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.1	GO:0030546	receptor activator activity(GO:0030546)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.0	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.8	GO:0003774	motor activity(GO:0003774)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.0	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:2001069	glycogen binding(GO:2001069)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID RAS PATHWAY	Regulation of Ras family activation
0.1	2.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	1.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.7	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.1	PID AURORA A PATHWAY	Aurora A signaling
0.0	2.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.8	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.5	PID ATM PATHWAY	ATM pathway
0.0	0.4	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	1.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	0.7	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.6	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	Genes involved in Platelet activation, signaling and aggregation
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	1.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response

Results for Nkx2-6

Z-value: 1.33

Motif logo

Transcription factors associated with Nkx2-6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nkx2-6 motif across conditions

Conditions sorted by the z-value of the Nkx2-6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: