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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nkx6-1_Evx1_Hesx1

Z-value: 5.66

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Transcription factors associated with Nkx6-1_Evx1_Hesx1

Gene Symbol	Gene ID	Gene Info
Nkx6-1 Ensembl NCBI MGI UniProt	ENSMUSG00000035187.8	NK6 homeobox 1
Evx1 Ensembl NCBI MGI UniProt	ENSMUSG00000005503.8	even-skipped homeobox 1
Hesx1 Ensembl NCBI MGI UniProt	ENSMUSG00000040726.8	homeobox gene expressed in ES cells

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_52305970_52306290	Evx1	7368	0.084143	0.08	5.9e-01	Click!
chr14_26994209_26994559	Hesx1	32	0.976517	-0.58	3.3e-06	Click!
chr14_26994627_26994778	Hesx1	286	0.905259	-0.41	1.8e-03	Click!
chr14_26991810_26991961	Hesx1	2531	0.267844	-0.22	1.1e-01	Click!
chr14_27000625_27000792	Hesx1	346	0.877379	-0.08	5.4e-01	Click!
chr14_27000375_27000536	Hesx1	93	0.969576	-0.06	6.7e-01	Click!
chr5_101663283_101663528	Nkx6-1	1591	0.382928	-0.39	3.3e-03	Click!
chr5_101665664_101665834	Nkx6-1	753	0.656733	0.24	7.5e-02	Click!
chr5_101665040_101665292	Nkx6-1	170	0.951637	0.14	3.0e-01	Click!
chr5_101664680_101664854	Nkx6-1	229	0.931488	0.14	3.2e-01	Click!
chr5_101663886_101664037	Nkx6-1	1035	0.533796	0.07	6.1e-01	Click!

Activity of the Nkx6-1_Evx1_Hesx1 motif across conditions

Conditions sorted by the z-value of the Nkx6-1_Evx1_Hesx1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_169838405_169838582	60.14	Mid1	midline 1	10334	0.25
chr17_11927079_11927230	60.05	Prkn	parkin RBR E3 ubiquitin protein ligase	81944	0.1
chr13_99444397_99444879	58.25	Map1b	microtubule-associated protein 1B	171	0.95
chr11_112501711_112502406	50.69	BC006965	cDNA sequence BC006965	167340	0.04
chr18_23036938_23037296	49.51	Nol4	nucleolar protein 4	1539	0.55
chr16_54195261_54195567	49.20	Gm49639	predicted gene, 49639	154914	0.04
chr12_58670274_58670654	47.60	Gm18873	predicted gene, 18873	93442	0.08
chr3_119021248_119021588	46.91	Gm43410	predicted gene 43410	153174	0.04
chr4_70811006_70811333	46.64	Gm11227	predicted gene 11227	261504	0.02
chr13_83750227_83750397	46.54	C130071C03Rik	RIKEN cDNA C130071C03 gene	11449	0.12
chr6_54552680_54553127	46.15	Scrn1	secernin 1	1543	0.37
chr14_55052295_55052661	45.85	Zfhx2os	zinc finger homeobox 2, opposite strand	1391	0.2
chr3_3832009_3832194	44.68	Gm2071	predicted gene 2071	2817	0.34
chr15_4378780_4379184	44.39	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3	3478	0.36
chr11_40624416_40624805	44.21	Gm12137	predicted gene 12137	11892	0.19
chr12_84532163_84533007	43.66	Lin52	lin-52 homolog (C. elegans)	2541	0.25
chr3_66102086_66102567	43.14	Gm36973	predicted gene, 36973	2521	0.19
chr2_72426764_72427187	42.99	Cdca7	cell division cycle associated 7	49184	0.13
chr3_78792451_78792970	42.64	Gm18952	predicted gene, 18952	34091	0.19
chr14_59737148_59737645	42.20	Gm19716	predicted gene, 19716	94848	0.07
chr2_168343654_168344081	41.96	Gm22704	predicted gene, 22704	8167	0.18
chr10_67559869_67560062	41.84	4930563J15Rik	RIKEN cDNA 4930563J15 gene	10073	0.12
chr3_139885937_139886924	41.07	Gm43678	predicted gene 43678	73666	0.11
chr6_12337029_12337231	40.75	Thsd7a	thrombospondin, type I, domain containing 7A	12437	0.3
chr17_93377556_93377754	40.54	Gm50001	predicted gene, 50001	14043	0.22
chr3_40673604_40673797	40.53	Intu	inturned planar cell polarity protein	1079	0.49
chr13_83749857_83750036	39.96	C130071C03Rik	RIKEN cDNA C130071C03 gene	11083	0.12
chr13_84751597_84751791	39.93	Gm26913	predicted gene, 26913	60753	0.15
chr18_86158490_86158809	39.87	Gm50381	predicted gene, 50381	61405	0.14
chr2_63669718_63669895	39.25	Gm23503	predicted gene, 23503	237612	0.02
chr15_40114597_40115428	38.89	9330182O14Rik	RIKEN cDNA 9330182O14 gene	19353	0.17
chr15_13989845_13990168	38.86	Gm49114	predicted gene, 49114	151949	0.04
chr15_74194149_74194481	38.86	Gm15387	predicted gene 15387	99982	0.07
chr16_7448068_7448264	38.70	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	95196	0.1
chr3_34561729_34562051	38.40	Sox2ot	SOX2 overlapping transcript (non-protein coding)	1498	0.34
chr11_25696299_25696505	38.33	Gm23514	predicted gene, 23514	11262	0.27
chr5_64476669_64477265	38.28	C030018K13Rik	RIKEN cDNA C030018K13 gene	41	0.96
chr14_59819298_59819449	38.22	Gm19716	predicted gene, 19716	176825	0.03
chr1_96346717_96347057	38.10	Gm37076	predicted gene, 37076	33645	0.18
chr3_17795323_17795845	38.06	Mir124a-2	microRNA 124a-2	78	0.62
chr1_167182388_167182722	37.85	Gm37994	predicted gene, 37994	3833	0.21
chr2_150735739_150736543	37.84	Gm28450	predicted gene 28450	11520	0.12
chr6_16727315_16727512	37.69	Gm36669	predicted gene, 36669	50111	0.17
chr12_51002047_51002408	37.55	Gm40421	predicted gene, 40421	2646	0.28
chr16_63806441_63806811	37.49	Epha3	Eph receptor A3	56787	0.15
chr11_40456488_40456834	37.32	3110004A20Rik	RIKEN cDNA 3110004A20 gene	19016	0.17
chr10_70458638_70458831	37.28	Fam13c	family with sequence similarity 13, member C	17808	0.19
chr2_165076987_165077575	37.12	1700025C18Rik	RIKEN cDNA 1700025C18 gene	13469	0.14
chr10_17479308_17479459	36.96	Gm47768	predicted gene, 47768	35347	0.16
chr1_46830172_46830391	36.80	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5618	0.22
chr5_5134656_5134845	36.79	Gm43623	predicted gene 43623	5357	0.21
chr4_39344820_39345025	36.76	Gm23607	predicted gene, 23607	49459	0.14
chr7_74687903_74688273	36.61	Gm7726	predicted gene 7726	11768	0.26
chr15_88468083_88468426	36.47	Zdhhc25	zinc finger, DHHC domain containing 25	132048	0.05
chr13_29370907_29371310	35.95	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	103499	0.08
chr10_16052455_16052829	35.88	C330004P14Rik	RIKEN cDNA C330004P14 gene	260865	0.02
chr3_39048326_39048698	35.86	Gm43539	predicted gene 43539	38831	0.19
chr2_56257440_56257969	35.83	Gm13518	predicted gene 13518	217851	0.02
chr14_115082136_115082318	35.79	Gpc5	glypican 5	9988	0.13
chr7_142902999_142903346	35.78	Th	tyrosine hydroxylase	3158	0.22
chr13_83739197_83739995	35.55	C130071C03Rik	RIKEN cDNA C130071C03 gene	733	0.33
chr14_12338097_12338549	35.43	Gm24578	predicted gene, 24578	4419	0.14
chr7_96865260_96865776	35.40	Gm25712	predicted gene, 25712	2139	0.28
chr6_107711195_107711474	35.37	4933431M02Rik	RIKEN cDNA 4933431M02 gene	83560	0.1
chr17_84749518_84749672	35.12	Lrpprc	leucine-rich PPR-motif containing	1667	0.35
chr13_116087410_116087561	34.98	Gm47893	predicted gene, 47893	8550	0.28
chr10_87501180_87501623	34.87	Gm48120	predicted gene, 48120	6461	0.19
chr16_67610911_67611282	34.87	Cadm2	cell adhesion molecule 2	9397	0.25
chr11_21713646_21713804	34.82	Wdpcp	WD repeat containing planar cell polarity effector	18596	0.2
chr15_95217343_95217494	34.79	1700129L04Rik	RIKEN cDNA 1700129L04 gene	55024	0.17
chr15_18190602_18190753	34.75	Gm8318	predicted gene 8318	26796	0.22
chr3_18456098_18456702	34.59	Gm30667	predicted gene, 30667	4854	0.24
chr5_78622542_78622942	34.48	Gm43232	predicted gene 43232	82214	0.11
chr6_6603963_6604155	34.44	Sem1	SEM1, 26S proteasome complex subunit	25396	0.18
chr7_72601928_72602360	34.41	Gm37620	predicted gene, 37620	155	0.96
chr19_59866689_59867059	34.24	Gm17203	predicted gene 17203	34188	0.18
chr6_17797574_17797931	34.17	Gm26738	predicted gene, 26738	37433	0.13
chr6_137699415_137699798	34.17	Strap	serine/threonine kinase receptor associated protein	35472	0.16
chr18_88785266_88785620	33.96	Socs6	suppressor of cytokine signaling 6	26952	0.17
chr17_63807674_63808197	33.83	Fer	fer (fms/fps related) protein kinase	55127	0.13
chr1_64066744_64067258	33.80	Gm13748	predicted gene 13748	11653	0.19
chr12_33225655_33225815	33.73	Atxn7l1os1	ataxin 7-like 1, opposite strand 1	3119	0.29
chr2_47834160_47834335	33.70	Gm25959	predicted gene, 25959	292263	0.01
chr16_74191732_74191898	33.64	Gm49658	predicted gene, 49658	684	0.72
chr13_43950070_43950222	33.56	Gm2233	predicted gene 2233	1267	0.5
chr19_27904687_27904996	33.42	Rfx3	regulatory factor X, 3 (influences HLA class II expression)	3946	0.29
chr2_54265163_54265368	33.36	Gm14035	predicted gene 14035	18850	0.21
chr1_176099027_176099243	33.21	Gm38081	predicted gene, 38081	66412	0.1
chr11_26806852_26807151	33.12	Gm12070	predicted gene 12070	20368	0.19
chr5_107497898_107498054	33.03	Btbd8	BTB (POZ) domain containing 8	197	0.9
chr10_31551495_31551682	32.96	Gm47693	predicted gene, 47693	5852	0.19
chrX_58445733_58445903	32.96	Gm14645	predicted gene 14645	17743	0.26
chr2_152069243_152069466	32.93	AA387200	expressed sequence AA387200	7454	0.15
chr1_6752243_6752413	32.91	St18	suppression of tumorigenicity 18	14753	0.25
chr7_78887666_78887880	32.82	Mir7-2	microRNA 7-2	504	0.68
chr12_90131976_90132183	32.61	Gm48700	predicted gene, 48700	63980	0.15
chr1_138497460_138497658	32.50	Gm28501	predicted gene 28501	18056	0.2
chr18_72725028_72725395	32.46	Gm31819	predicted gene, 31819	144	0.98
chr11_93488029_93488206	32.42	Gm24856	predicted gene, 24856	74793	0.12
chr2_57522938_57523151	32.34	Gm13531	predicted gene 13531	97335	0.07
chr9_61102454_61102622	32.29	4933433G08Rik	RIKEN cDNA 4933433G08 gene	2847	0.2
chr7_64884497_64884825	32.28	Nsmce3	NSE3 homolog, SMC5-SMC6 complex component	11664	0.22
chr10_15249538_15249689	32.17	Gm18188	predicted gene, 18188	21565	0.23
chr10_32871097_32871256	32.16	Nkain2	Na+/K+ transporting ATPase interacting 2	18520	0.25
chr12_44839950_44840386	32.06	Gm15901	predicted gene 15901	83012	0.1
chr2_123364591_123364759	32.00	Gm13988	predicted gene 13988	90751	0.1
chr2_146763416_146764171	31.96	Gm14111	predicted gene 14111	8088	0.27
chr2_106512677_106513062	31.94	Gm14015	predicted gene 14015	10234	0.26
chr6_15397521_15397861	31.94	Gm25470	predicted gene, 25470	7290	0.26
chr7_16147163_16147320	31.87	Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	16893	0.11
chr6_138754677_138754895	31.84	Igbp1b	immunoglobulin (CD79A) binding protein 1b	96242	0.08
chr6_61066614_61066949	31.78	Gm43893	predicted gene, 43893	2474	0.28
chr15_44705846_44706012	31.64	Sybu	syntabulin (syntaxin-interacting)	41859	0.15
chr9_33630065_33630387	31.53	Gm47778	predicted gene, 47778	32861	0.21
chr10_29143863_29144732	31.53	Gm9996	predicted gene 9996	103	0.69
chr1_159015364_159015547	31.53	Pappa2	pappalysin 2	34965	0.17
chr7_64579951_64580289	31.50	Gm44721	predicted gene 44721	50695	0.12
chr11_32019966_32020621	31.31	Nsg2	neuron specific gene family member 2	19791	0.19
chr9_10526392_10526546	31.25	Gm46103	predicted gene, 46103	50534	0.17
chr2_28780313_28780498	31.20	Gm13385	predicted gene 13385	13164	0.13
chr12_29789878_29790063	31.14	Myt1l	myelin transcription factor 1-like	50240	0.17
chr4_28143160_28143344	31.03	Gm11911	predicted gene 11911	76075	0.11
chr18_8044886_8045210	31.02	Gm4833	predicted gene 4833	6155	0.28
chr13_52457883_52458068	30.94	Diras2	DIRAS family, GTP-binding RAS-like 2	73304	0.12
chr2_123799511_123799723	30.87	Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	290352	0.01
chr8_13454338_13454755	30.82	Tmem255b	transmembrane protein 255B	932	0.51
chr18_78455374_78455574	30.81	4931439C15Rik	RIKEN cDNA 4931439C15 gene	21404	0.24
chr8_86961518_86961711	30.80	Gm24781	predicted gene, 24781	4005	0.19
chr2_142335542_142335810	30.78	Macrod2	mono-ADP ribosylhydrolase 2	159069	0.04
chr6_127449629_127449900	30.77	Parp11	poly (ADP-ribose) polymerase family, member 11	501	0.78
chr4_24213358_24214284	30.72	Gm11892	predicted gene 11892	24279	0.27
chr2_63669900_63670081	30.69	Gm23503	predicted gene, 23503	237796	0.02
chr5_9044913_9045065	30.63	Gm40264	predicted gene, 40264	9865	0.15
chr19_59697672_59697945	30.59	Gm50411	predicted gene, 50411	7074	0.25
chr8_26677560_26678005	30.55	Gm32098	predicted gene, 32098	9476	0.18
chr2_41498351_41498548	30.51	Lrp1b	low density lipoprotein-related protein 1B	290629	0.01
chr5_13312689_13312966	30.48	Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	83957	0.09
chr3_47668909_47669138	30.48	Gm2229	predicted gene 2229	208685	0.03
chr8_47642536_47642697	30.44	Gm8623	predicted gene 8623	9852	0.12
chr7_111896291_111896806	30.41	Gm45588	predicted gene 45588	37993	0.17
chr9_5752747_5752938	30.35	Gm48506	predicted gene, 48506	43937	0.19
chr12_78987630_78988054	30.22	Tmem229b	transmembrane protein 229B	4364	0.21
chr11_39596506_39596789	30.15	Gm12131	predicted gene 12131	131065	0.06
chr4_24429638_24429836	30.11	Gm27243	predicted gene 27243	1153	0.54
chr8_89135140_89135331	30.06	Gm6625	predicted gene 6625	11823	0.24
chr17_8368820_8369004	30.06	T2	brachyury 2	3484	0.15
chr13_84783651_84783837	30.05	Gm26913	predicted gene, 26913	92803	0.09
chr6_23243851_23244662	30.00	Fezf1	Fez family zinc finger 1	4106	0.2
chr11_47459324_47459525	29.99	Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	79902	0.11
chr4_148291962_148292123	29.95	Disp3	dispatched RND transporter family member 3	4077	0.19
chr1_135645775_135646042	29.92	Nav1	neuron navigator 1	42197	0.12
chr13_24656992_24657522	29.85	Ripor2	RHO family interacting cell polarization regulator 2	15682	0.19
chr13_101019238_101019730	29.84	Gm6114	predicted gene 6114	5498	0.21
chr5_106577367_106577576	29.81	Gm29464	predicted gene 29464	2596	0.19
chrX_60545622_60545821	29.70	Gm715	predicted gene 715	2298	0.23
chr10_19396813_19397100	29.68	Olig3	oligodendrocyte transcription factor 3	40423	0.16
chr15_59973915_59974066	29.67	Gm7083	predicted gene 7083	3732	0.23
chr12_96114939_96115347	29.62	1700019M22Rik	RIKEN cDNA 1700019M22 gene	68023	0.13
chr18_74956688_74957137	29.57	Lipg	lipase, endothelial	4350	0.11
chr18_74907209_74907702	29.50	Gm24559	predicted gene, 24559	1021	0.37
chr11_44785172_44785367	29.44	Gm12158	predicted gene 12158	122593	0.05
chr1_157969609_157969781	29.26	Gm38256	predicted gene, 38256	29310	0.25
chr7_129392977_129393128	29.13	Gm33027	predicted gene, 33027	10038	0.29
chr2_132427639_132427949	29.13	4921508D12Rik	RIKEN cDNA 4921508D12 gene	3053	0.25
chr17_76111639_76112128	29.12	Gm24126	predicted gene, 24126	37337	0.22
chr3_75085844_75086059	29.12	Zbbx	zinc finger, B-box domain containing	57752	0.14
chr6_40024235_40024578	29.02	Gm37995	predicted gene, 37995	2488	0.33
chr13_82620860_82621103	29.01	Mir3961	microRNA 3961	77352	0.12
chr1_165914170_165914334	28.93	Pou2f1	POU domain, class 2, transcription factor 1	969	0.48
chr8_58372581_58372772	28.92	Gm45635	predicted gene 45635	126089	0.06
chr6_127701185_127701975	28.88	Gm43634	predicted gene 43634	57140	0.08
chr13_78181182_78181614	28.85	Gm38604	predicted gene, 38604	1761	0.26
chr5_116895407_116895611	28.81	Gm43122	predicted gene 43122	64955	0.1
chr2_50971381_50971555	28.74	Gm13498	predicted gene 13498	61784	0.14
chr14_64233778_64233929	28.71	9630015K15Rik	RIKEN cDNA 9630015K15 gene	117539	0.05
chr13_78100021_78100517	28.71	C130051F05Rik	RIKEN cDNA C130051F05 gene	12213	0.15
chr4_87739581_87739778	28.70	Mllt3	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3	66615	0.13
chr4_97235906_97236408	28.63	Gm12696	predicted gene 12696	286175	0.01
chr18_17383276_17383802	28.52	4921533I20Rik	Riken cDNA 4921533I20 gene	63809	0.15
chr17_69686012_69686193	28.49	Gm49895	predicted gene, 49895	89910	0.08
chr7_67468944_67469359	28.48	Gm33926	predicted gene, 33926	25218	0.17
chr16_59854456_59854822	28.46	Epha6	Eph receptor A6	151082	0.04
chr13_64527016_64527226	28.41	Gm47190	predicted gene, 47190	11267	0.13
chr14_78132773_78132953	28.39	Fam216b	family with sequence similarity 216, member B	43856	0.12
chr3_34504632_34504783	28.35	Gm29135	predicted gene 29135	22500	0.16
chr15_18190039_18190239	28.29	Gm8318	predicted gene 8318	26258	0.22
chr2_57916465_57916651	28.28	Gm33594	predicted gene, 33594	69459	0.11
chr6_61042953_61043250	28.20	Gm43892	predicted gene, 43892	1892	0.33
chr15_66486114_66486277	28.15	Lrrc6	leucine rich repeat containing 6 (testis)	14715	0.23
chr1_69046688_69046868	28.11	Gm16076	predicted gene 16076	59962	0.13
chr8_49462101_49462489	28.07	4930555F03Rik	RIKEN cDNA 4930555F03 gene	1028	0.5
chr6_23280695_23281211	28.02	C130093G08Rik	RIKEN cDNA C130093G08 gene	29820	0.15
chr8_97397028_97397210	27.97	Gm5913	predicted gene 5913	31991	0.2
chr3_134605538_134605802	27.96	Gm26820	predicted gene, 26820	25095	0.24
chr4_24429061_24429567	27.95	Gm27243	predicted gene 27243	1576	0.43
chr4_6912973_6913331	27.85	Tox	thymocyte selection-associated high mobility group box	77331	0.11
chr6_103514048_103514248	27.81	Chl1	cell adhesion molecule L1-like	2818	0.24
chr11_41532495_41533004	27.79	Hspd1-ps3	heat shock protein 1 (chaperonin), pseudogene 3	34012	0.2
chr10_51153683_51154077	27.74	Gm26257	predicted gene, 26257	28419	0.22
chr5_60599748_60600063	27.71	Gm43390	predicted gene 43390	21275	0.23

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
29.9	89.8	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
14.8	88.7	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
13.9	41.8	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
13.5	54.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
12.2	24.3	GO:0021780	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
11.6	11.6	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
10.9	76.0	GO:0016198	axon choice point recognition(GO:0016198)
10.5	31.5	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
10.5	42.0	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
10.2	91.8	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
9.1	27.2	GO:0032289	central nervous system myelin formation(GO:0032289)
8.9	26.8	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
8.9	26.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
8.5	25.5	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
8.4	67.5	GO:0021796	cerebral cortex regionalization(GO:0021796)
8.3	25.0	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
8.0	8.0	GO:0006106	fumarate metabolic process(GO:0006106)
8.0	32.1	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
8.0	40.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
7.7	30.6	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
7.6	30.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
7.5	82.3	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
7.5	22.4	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
7.4	22.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
7.0	14.0	GO:1903802	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
6.7	20.0	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
6.6	26.3	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
6.5	19.4	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
6.3	50.6	GO:0045161	neuronal ion channel clustering(GO:0045161)
6.3	18.9	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
6.2	43.2	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
6.0	18.1	GO:0060178	regulation of exocyst localization(GO:0060178)
5.9	17.6	GO:2000981	negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
5.7	17.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
5.4	43.6	GO:0035881	amacrine cell differentiation(GO:0035881)
5.3	53.1	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
5.1	10.1	GO:0048880	sensory system development(GO:0048880)
4.9	9.8	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
4.9	9.7	GO:0003358	noradrenergic neuron development(GO:0003358)
4.8	24.1	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
4.8	14.4	GO:0046684	response to pyrethroid(GO:0046684)
4.8	14.4	GO:0030070	insulin processing(GO:0030070)
4.8	9.5	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
4.7	9.5	GO:0089700	protein kinase D signaling(GO:0089700)
4.7	14.1	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
4.7	32.9	GO:0050957	equilibrioception(GO:0050957)
4.7	14.1	GO:0001661	conditioned taste aversion(GO:0001661)
4.7	18.8	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
4.6	13.9	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
4.6	13.7	GO:0021960	anterior commissure morphogenesis(GO:0021960)
4.6	18.3	GO:0006538	glutamate catabolic process(GO:0006538)
4.6	13.7	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
4.5	13.6	GO:0007412	axon target recognition(GO:0007412)
4.5	27.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
4.5	22.6	GO:1903887	motile primary cilium assembly(GO:1903887)
4.4	4.4	GO:0061642	chemoattraction of axon(GO:0061642)
4.3	17.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
4.3	8.6	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.3	4.3	GO:0021564	vagus nerve development(GO:0021564)
4.2	72.0	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
4.2	12.5	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
4.2	12.5	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
4.2	20.8	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
4.1	24.9	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
4.1	20.6	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
4.1	8.2	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282) metanephric nephron tubule formation(GO:0072289)
4.1	16.4	GO:0007258	JUN phosphorylation(GO:0007258)
4.0	32.3	GO:0021871	forebrain regionalization(GO:0021871)
4.0	8.0	GO:0072221	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
4.0	4.0	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
3.9	7.9	GO:0021559	trigeminal nerve development(GO:0021559)
3.9	3.9	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
3.9	7.7	GO:0060174	limb bud formation(GO:0060174)
3.9	11.6	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
3.8	11.5	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
3.8	3.8	GO:0021859	pyramidal neuron differentiation(GO:0021859)
3.6	14.6	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
3.6	14.5	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
3.6	10.9	GO:0070634	transepithelial ammonium transport(GO:0070634)
3.6	28.8	GO:0071625	vocalization behavior(GO:0071625)
3.6	32.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
3.6	3.6	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
3.6	14.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
3.6	3.6	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
3.5	14.1	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
3.5	14.0	GO:1903977	positive regulation of glial cell migration(GO:1903977)
3.5	7.0	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
3.4	6.9	GO:0021553	olfactory nerve development(GO:0021553)
3.4	6.8	GO:0060594	mammary gland specification(GO:0060594)
3.4	13.5	GO:0009957	epidermal cell fate specification(GO:0009957)
3.4	40.6	GO:0016082	synaptic vesicle priming(GO:0016082)
3.4	10.1	GO:0046959	habituation(GO:0046959)
3.3	6.7	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.3	10.0	GO:1903061	positive regulation of protein lipidation(GO:1903061)
3.3	10.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
3.3	19.8	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
3.3	19.7	GO:0022605	oogenesis stage(GO:0022605)
3.2	13.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
3.2	9.7	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
3.2	70.5	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
3.2	9.6	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
3.2	12.8	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
3.2	12.7	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
3.2	6.3	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
3.2	22.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
3.1	12.6	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
3.1	9.4	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
3.1	9.4	GO:0032672	regulation of interleukin-3 production(GO:0032672)
3.1	25.1	GO:0046069	cGMP catabolic process(GO:0046069)
3.1	25.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
3.1	25.0	GO:0060179	male mating behavior(GO:0060179)
3.1	9.3	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1	3.1	GO:0097154	GABAergic neuron differentiation(GO:0097154)
3.1	15.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
3.0	15.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
3.0	15.0	GO:0007256	activation of JNKK activity(GO:0007256)
2.9	8.8	GO:1901475	pyruvate transmembrane transport(GO:1901475)
2.9	20.5	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
2.9	8.7	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
2.8	11.2	GO:0001834	trophectodermal cell proliferation(GO:0001834)
2.8	16.8	GO:0035641	locomotory exploration behavior(GO:0035641)
2.8	14.0	GO:0048496	maintenance of organ identity(GO:0048496)
2.8	5.6	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
2.7	8.2	GO:0006553	lysine metabolic process(GO:0006553)
2.7	8.2	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
2.7	32.8	GO:0002329	pre-B cell differentiation(GO:0002329)
2.7	13.6	GO:0048681	negative regulation of axon regeneration(GO:0048681)
2.7	2.7	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
2.7	21.6	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
2.7	156.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
2.7	8.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.7	8.0	GO:0001927	exocyst assembly(GO:0001927)
2.6	10.6	GO:0060279	positive regulation of ovulation(GO:0060279)
2.6	7.9	GO:0002314	germinal center B cell differentiation(GO:0002314)
2.6	10.5	GO:0048852	diencephalon morphogenesis(GO:0048852)
2.6	7.9	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
2.6	36.7	GO:0010842	retina layer formation(GO:0010842)
2.6	10.5	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
2.6	5.2	GO:0090427	activation of meiosis(GO:0090427)
2.6	7.8	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
2.6	10.4	GO:0098904	regulation of AV node cell action potential(GO:0098904)
2.6	28.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
2.5	2.5	GO:0086066	atrial cardiac muscle cell action potential(GO:0086014) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
2.5	42.4	GO:0001964	startle response(GO:0001964)
2.5	12.4	GO:0090273	regulation of somatostatin secretion(GO:0090273)
2.5	7.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
2.5	2.5	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
2.4	19.5	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
2.4	4.9	GO:0060005	vestibular reflex(GO:0060005)
2.4	7.3	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
2.4	21.9	GO:0006570	tyrosine metabolic process(GO:0006570)
2.4	7.3	GO:1990035	calcium ion import into cell(GO:1990035)
2.4	14.4	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.4	12.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
2.4	12.0	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.4	7.2	GO:2000680	regulation of rubidium ion transport(GO:2000680) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
2.4	2.4	GO:0021861	forebrain radial glial cell differentiation(GO:0021861)
2.4	9.4	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
2.3	9.4	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
2.3	18.8	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
2.3	4.6	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
2.3	11.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
2.3	6.8	GO:0030242	pexophagy(GO:0030242)
2.2	15.6	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
2.2	2.2	GO:0060221	retinal rod cell differentiation(GO:0060221)
2.2	13.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
2.2	2.2	GO:1902221	L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
2.2	166.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.2	2.2	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
2.2	6.5	GO:0051964	negative regulation of synapse assembly(GO:0051964)
2.2	26.0	GO:0048268	clathrin coat assembly(GO:0048268)
2.1	10.7	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
2.1	4.3	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
2.1	6.4	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
2.1	4.3	GO:0072092	ureteric bud invasion(GO:0072092)
2.1	12.6	GO:0060581	ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
2.1	4.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
2.1	4.2	GO:0060166	olfactory pit development(GO:0060166)
2.1	10.3	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
2.1	6.2	GO:0021542	dentate gyrus development(GO:0021542)
2.0	8.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
2.0	6.0	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
2.0	13.9	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
2.0	9.9	GO:0019532	oxalate transport(GO:0019532)
2.0	7.9	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
2.0	2.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
1.9	5.8	GO:0033564	anterior/posterior axon guidance(GO:0033564)
1.9	7.7	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.9	9.6	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.9	3.8	GO:0033693	neurofilament bundle assembly(GO:0033693)
1.9	3.8	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
1.9	7.7	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
1.9	9.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.9	7.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.9	7.6	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.9	3.8	GO:0007158	neuron cell-cell adhesion(GO:0007158)
1.9	7.6	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
1.9	5.6	GO:0019673	GDP-mannose metabolic process(GO:0019673)
1.9	7.4	GO:0035627	ceramide transport(GO:0035627)
1.8	27.7	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
1.8	5.5	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
1.8	8.9	GO:0071397	cellular response to cholesterol(GO:0071397)
1.8	3.6	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.8	7.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.8	3.5	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
1.8	1.8	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.7	17.2	GO:0071803	positive regulation of podosome assembly(GO:0071803)
1.7	5.2	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.7	1.7	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
1.7	3.4	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
1.7	13.6	GO:0071435	potassium ion export(GO:0071435)
1.7	3.4	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
1.7	10.2	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.7	8.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
1.7	6.8	GO:0021979	hypothalamus cell differentiation(GO:0021979)
1.7	5.1	GO:0048388	endosomal lumen acidification(GO:0048388)
1.7	5.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.7	3.4	GO:0051654	establishment of mitochondrion localization(GO:0051654)
1.7	3.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.7	5.0	GO:0021877	forebrain neuron fate commitment(GO:0021877)
1.7	1.7	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
1.7	6.6	GO:0006166	purine ribonucleoside salvage(GO:0006166)
1.7	5.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
1.6	4.9	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
1.6	4.8	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
1.6	6.4	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
1.6	4.8	GO:2000574	regulation of microtubule motor activity(GO:2000574)
1.6	8.0	GO:0006348	chromatin silencing at telomere(GO:0006348)
1.6	3.2	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
1.6	4.8	GO:0042126	nitrate metabolic process(GO:0042126)
1.6	6.4	GO:0000160	phosphorelay signal transduction system(GO:0000160)
1.6	1.6	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.6	4.7	GO:0006562	proline catabolic process(GO:0006562)
1.6	4.7	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
1.6	4.7	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.6	4.7	GO:0014826	vein smooth muscle contraction(GO:0014826)
1.6	6.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
1.5	3.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
1.5	4.6	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
1.5	1.5	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.5	1.5	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
1.5	4.6	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.5	3.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
1.5	3.0	GO:0009629	response to gravity(GO:0009629)
1.5	13.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.5	17.8	GO:0016486	peptide hormone processing(GO:0016486)
1.5	5.9	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
1.5	7.4	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
1.5	5.8	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.5	2.9	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
1.5	5.8	GO:0030091	protein repair(GO:0030091)
1.5	4.4	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
1.4	4.3	GO:1903999	negative regulation of eating behavior(GO:1903999)
1.4	5.7	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
1.4	8.5	GO:0018344	protein geranylgeranylation(GO:0018344)
1.4	4.3	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
1.4	7.1	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
1.4	5.6	GO:0090148	membrane fission(GO:0090148)
1.4	5.6	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
1.4	4.2	GO:0002034	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
1.4	4.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.4	4.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
1.4	8.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
1.4	5.5	GO:0048341	paraxial mesoderm formation(GO:0048341)
1.4	4.1	GO:0006177	GMP biosynthetic process(GO:0006177)
1.4	1.4	GO:1903935	response to sodium arsenite(GO:1903935)
1.4	1.4	GO:0097374	sensory neuron axon guidance(GO:0097374)
1.4	2.7	GO:1901529	positive regulation of anion channel activity(GO:1901529)
1.4	2.7	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
1.3	9.4	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
1.3	2.7	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.3	2.7	GO:0000101	sulfur amino acid transport(GO:0000101)
1.3	1.3	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
1.3	2.7	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
1.3	7.8	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.3	1.3	GO:0061196	fungiform papilla development(GO:0061196)
1.3	3.8	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.3	15.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
1.3	3.8	GO:0003219	cardiac right ventricle formation(GO:0003219)
1.3	3.8	GO:0014075	response to amine(GO:0014075)
1.2	5.0	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
1.2	6.2	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.2	1.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.2	7.4	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
1.2	3.7	GO:0060468	prevention of polyspermy(GO:0060468)
1.2	6.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
1.2	34.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.2	3.6	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
1.2	2.4	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
1.2	4.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.2	2.4	GO:0002930	trabecular meshwork development(GO:0002930)
1.2	7.2	GO:0007262	STAT protein import into nucleus(GO:0007262)
1.2	1.2	GO:0035826	rubidium ion transport(GO:0035826)
1.2	25.1	GO:0006376	mRNA splice site selection(GO:0006376)
1.2	4.8	GO:0070365	hepatocyte differentiation(GO:0070365)
1.2	1.2	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.2	1.2	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
1.2	1.2	GO:0010996	response to auditory stimulus(GO:0010996)
1.2	7.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.2	1.2	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
1.2	1.2	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.2	4.7	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
1.2	14.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
1.2	10.4	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
1.1	8.0	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
1.1	4.6	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.1	5.7	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
1.1	2.3	GO:0046098	guanine metabolic process(GO:0046098)
1.1	2.3	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.1	3.4	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.1	4.5	GO:0034239	regulation of macrophage fusion(GO:0034239)
1.1	4.4	GO:0005513	detection of calcium ion(GO:0005513)
1.1	1.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
1.1	8.8	GO:0097120	receptor localization to synapse(GO:0097120)
1.1	5.4	GO:2000811	negative regulation of anoikis(GO:2000811)
1.1	5.3	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
1.1	2.1	GO:0030035	microspike assembly(GO:0030035)
1.1	5.3	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.1	1.1	GO:0097195	pilomotor reflex(GO:0097195)
1.1	5.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.1	7.4	GO:0001504	neurotransmitter uptake(GO:0001504)
1.1	2.1	GO:0060872	semicircular canal development(GO:0060872)
1.0	1.0	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
1.0	1.0	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
1.0	8.2	GO:0060736	prostate gland growth(GO:0060736)
1.0	1.0	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
1.0	2.0	GO:0071873	response to norepinephrine(GO:0071873)
1.0	2.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
1.0	2.0	GO:0038128	ERBB2 signaling pathway(GO:0038128)
1.0	3.0	GO:2000774	positive regulation of cellular senescence(GO:2000774)
1.0	4.0	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
1.0	1.0	GO:0090135	actin filament branching(GO:0090135)
1.0	4.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
1.0	5.9	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.0	3.0	GO:0072318	clathrin coat disassembly(GO:0072318)
1.0	4.9	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
1.0	2.0	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
1.0	1.9	GO:0007638	mechanosensory behavior(GO:0007638)
1.0	2.9	GO:0030432	peristalsis(GO:0030432)
1.0	3.8	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.9	2.8	GO:0006203	dGTP catabolic process(GO:0006203)
0.9	17.1	GO:0003407	neural retina development(GO:0003407)
0.9	3.8	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.9	0.9	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.9	2.8	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.9	2.8	GO:0051541	elastin metabolic process(GO:0051541)
0.9	4.6	GO:0015808	L-alanine transport(GO:0015808)
0.9	6.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.9	3.7	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.9	9.2	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.9	1.8	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.9	3.7	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.9	2.7	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.9	3.6	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.9	0.9	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.9	3.6	GO:0006642	triglyceride mobilization(GO:0006642)
0.9	2.7	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.9	10.9	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.9	8.1	GO:0006983	ER overload response(GO:0006983)
0.9	0.9	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.9	1.8	GO:0097212	lysosomal membrane organization(GO:0097212)
0.9	2.7	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.9	4.5	GO:0048840	otolith development(GO:0048840)
0.9	5.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.9	3.5	GO:0016322	neuron remodeling(GO:0016322)
0.9	7.9	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.9	2.6	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.9	1.7	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.9	0.9	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.9	1.7	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.9	4.3	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.9	14.8	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.9	5.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.9	0.9	GO:0050932	regulation of pigment cell differentiation(GO:0050932)
0.8	2.5	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.8	3.4	GO:0070126	mitochondrial translational termination(GO:0070126)
0.8	1.7	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.8	0.8	GO:0072199	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
0.8	5.7	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.8	1.6	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.8	5.6	GO:0015816	glycine transport(GO:0015816)
0.8	5.6	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.8	1.6	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.8	2.4	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.8	1.6	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.8	4.0	GO:0021854	hypothalamus development(GO:0021854)
0.8	0.8	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.8	1.6	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.8	0.8	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.8	1.6	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.8	5.5	GO:0003356	regulation of cilium beat frequency(GO:0003356)
0.8	1.6	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.8	4.7	GO:0002093	auditory receptor cell morphogenesis(GO:0002093)
0.8	0.8	GO:2000040	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.8	7.0	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.8	0.8	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.8	3.8	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.8	1.5	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.8	2.3	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977)
0.8	2.3	GO:0090382	phagosome maturation(GO:0090382)
0.8	1.5	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.8	6.8	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.8	3.0	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.8	3.0	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.8	1.5	GO:2000821	regulation of grooming behavior(GO:2000821)
0.7	3.7	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.7	2.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.7	4.4	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.7	1.5	GO:0099515	actin filament-based transport(GO:0099515)
0.7	2.2	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.7	0.7	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.7	5.1	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.7	2.9	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.7	2.9	GO:0006517	protein deglycosylation(GO:0006517)
0.7	3.6	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.7	0.7	GO:0036301	macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.7	2.9	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.7	2.9	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.7	1.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.7	4.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.7	1.4	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.7	2.8	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.7	2.1	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.7	2.1	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.7	4.9	GO:0006450	regulation of translational fidelity(GO:0006450)
0.7	2.8	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.7	0.7	GO:0009750	response to fructose(GO:0009750)
0.7	20.1	GO:0001755	neural crest cell migration(GO:0001755)
0.7	1.4	GO:0046070	dGTP metabolic process(GO:0046070)
0.7	4.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.7	3.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.7	9.6	GO:0008210	estrogen metabolic process(GO:0008210)
0.7	2.0	GO:0097384	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.7	3.4	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.7	2.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.7	2.0	GO:0023041	neuronal signal transduction(GO:0023041)
0.7	0.7	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.7	4.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.7	2.0	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.7	23.5	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.7	8.0	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.7	0.7	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.7	2.7	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.7	7.3	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.7	2.0	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.7	0.7	GO:0048242	epinephrine secretion(GO:0048242)
0.7	2.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.7	0.7	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.7	1.3	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.6	2.6	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.6	1.3	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.6	1.3	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.6	1.9	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.6	10.6	GO:0021954	central nervous system neuron development(GO:0021954)
0.6	1.9	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.6	5.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.6	4.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.6	11.1	GO:0007616	long-term memory(GO:0007616)
0.6	1.8	GO:2001023	regulation of response to drug(GO:2001023)
0.6	0.6	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.6	15.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.6	1.2	GO:0009204	deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.6	1.2	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.6	1.7	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.6	1.7	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.6	0.6	GO:0071481	cellular response to X-ray(GO:0071481)
0.6	1.7	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.6	0.6	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.6	2.3	GO:0051697	protein delipidation(GO:0051697)
0.6	3.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.6	3.4	GO:0006108	malate metabolic process(GO:0006108)
0.6	1.7	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.6	2.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.6	10.0	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.5	2.7	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.5	1.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.5	1.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.5	4.4	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.5	0.5	GO:0090494	catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.5	1.6	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.5	4.3	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5	30.9	GO:0007612	learning(GO:0007612)
0.5	3.2	GO:0051451	myoblast migration(GO:0051451)
0.5	1.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.5	4.8	GO:0001710	mesodermal cell fate commitment(GO:0001710)
0.5	1.1	GO:0010046	response to mycotoxin(GO:0010046)
0.5	0.5	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.5	7.4	GO:0035855	megakaryocyte development(GO:0035855)
0.5	1.0	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.5	15.7	GO:0006998	nuclear envelope organization(GO:0006998)
0.5	2.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.5	0.5	GO:0021554	optic nerve development(GO:0021554)
0.5	1.5	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.5	1.0	GO:0035315	hair cell differentiation(GO:0035315)
0.5	4.5	GO:0035428	hexose transmembrane transport(GO:0035428)
0.5	2.5	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.5	3.5	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.5	2.5	GO:0009235	cobalamin metabolic process(GO:0009235)
0.5	5.9	GO:0008045	motor neuron axon guidance(GO:0008045)
0.5	3.4	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.5	1.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.5	8.2	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.5	1.9	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.5	1.4	GO:0043615	astrocyte cell migration(GO:0043615)
0.5	1.9	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.5	1.9	GO:0003157	endocardium development(GO:0003157)
0.5	1.9	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.5	0.9	GO:0071288	cellular response to mercury ion(GO:0071288)
0.5	1.4	GO:0048478	replication fork protection(GO:0048478)
0.5	0.5	GO:0032058	positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
0.5	1.4	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.5	0.9	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.5	0.9	GO:0044065	regulation of respiratory system process(GO:0044065)
0.5	1.8	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.5	1.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.5	1.4	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.5	2.3	GO:2000615	regulation of histone H3-K9 acetylation(GO:2000615)
0.5	10.0	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.5	0.5	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.5	0.9	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.5	0.5	GO:1903358	regulation of Golgi organization(GO:1903358)
0.4	0.9	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.4	0.4	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4	1.8	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.4	6.7	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.4	1.3	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4	1.3	GO:0034214	protein hexamerization(GO:0034214)
0.4	2.2	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.4	1.3	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.4	3.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.4	3.5	GO:0043249	erythrocyte maturation(GO:0043249)
0.4	8.3	GO:0006491	N-glycan processing(GO:0006491)
0.4	1.7	GO:0036093	germ cell proliferation(GO:0036093)
0.4	1.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.4	1.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.4	0.4	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.4	1.3	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.4	0.4	GO:0051665	membrane raft localization(GO:0051665)
0.4	3.7	GO:0021766	hippocampus development(GO:0021766)
0.4	5.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.4	1.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4	6.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.4	1.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.4	0.8	GO:0060467	negative regulation of fertilization(GO:0060467)
0.4	1.2	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.4	0.4	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.4	9.1	GO:0006270	DNA replication initiation(GO:0006270)
0.4	0.4	GO:0042713	sperm ejaculation(GO:0042713)
0.4	2.0	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.4	1.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4	1.9	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.4	0.8	GO:0048254	snoRNA localization(GO:0048254)
0.4	0.4	GO:0002434	immune complex clearance(GO:0002434)
0.4	2.2	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4	4.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.4	1.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.4	0.7	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4	6.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.4	2.5	GO:0070570	regulation of neuron projection regeneration(GO:0070570)
0.4	0.4	GO:0032252	secretory granule localization(GO:0032252)
0.4	5.8	GO:0021591	ventricular system development(GO:0021591)
0.4	10.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.4	2.9	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.4	1.4	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4	4.7	GO:0030497	fatty acid elongation(GO:0030497)
0.4	0.7	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4	1.1	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.3	1.0	GO:0032026	response to magnesium ion(GO:0032026)
0.3	0.7	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.3	0.7	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.3	1.0	GO:0048014	Tie signaling pathway(GO:0048014)
0.3	6.2	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.3	0.3	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.3	1.3	GO:0002423	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858)
0.3	1.3	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.3	1.3	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	0.7	GO:0007442	hindgut morphogenesis(GO:0007442)
0.3	1.6	GO:0097066	response to thyroid hormone(GO:0097066)
0.3	3.0	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.3	0.7	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.3	5.5	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3	0.7	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.3	1.3	GO:0006449	regulation of translational termination(GO:0006449)
0.3	0.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.3	0.6	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3	2.6	GO:0006183	GTP biosynthetic process(GO:0006183)
0.3	3.2	GO:0003016	respiratory system process(GO:0003016)
0.3	2.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.3	0.3	GO:0060013	righting reflex(GO:0060013)
0.3	0.9	GO:1900368	regulation of RNA interference(GO:1900368)
0.3	1.3	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.3	0.3	GO:0010966	regulation of phosphate transport(GO:0010966)
0.3	0.3	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.3	0.6	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.3	0.6	GO:0031133	regulation of axon diameter(GO:0031133)
0.3	0.9	GO:0046208	spermine catabolic process(GO:0046208)
0.3	1.5	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.3	2.4	GO:1904871	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.3	0.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.3	2.1	GO:0035773	insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.3	3.5	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.3	1.5	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3	1.7	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.3	0.3	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.3	4.0	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.3	0.3	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3	0.6	GO:0048148	behavioral response to cocaine(GO:0048148)
0.3	0.9	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.3	3.4	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.3	0.8	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.3	2.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.3	1.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.3	0.8	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.3	0.8	GO:0043576	regulation of respiratory gaseous exchange(GO:0043576)
0.3	1.8	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3	0.8	GO:0003032	detection of oxygen(GO:0003032)
0.3	0.5	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.3	0.3	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2	0.7	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2	1.0	GO:0042473	outer ear morphogenesis(GO:0042473)
0.2	4.6	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.2	0.5	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.2	0.7	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.2	1.7	GO:0072505	divalent inorganic anion homeostasis(GO:0072505)
0.2	0.7	GO:0009233	menaquinone metabolic process(GO:0009233)
0.2	0.7	GO:0006551	leucine metabolic process(GO:0006551)
0.2	0.2	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.2	18.5	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.2	0.5	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.2	0.5	GO:1901858	regulation of mitochondrial DNA metabolic process(GO:1901858)
0.2	0.5	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	1.6	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	1.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	0.9	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2	0.6	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	0.2	GO:0042420	dopamine catabolic process(GO:0042420)
0.2	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2	0.6	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2	0.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.2	1.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2	0.8	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.2	0.2	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.2	0.6	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2	0.6	GO:0022417	protein maturation by protein folding(GO:0022417)
0.2	0.8	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.2	0.6	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.2	0.6	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.2	0.2	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.2	1.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.2	0.2	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2	0.2	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.2	2.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.2	0.5	GO:0000733	DNA strand renaturation(GO:0000733)
0.2	0.5	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.2	0.2	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2	0.5	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2	0.4	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.2	2.5	GO:0034587	piRNA metabolic process(GO:0034587)
0.2	0.5	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.2	0.5	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.2	1.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	0.2	GO:0030421	defecation(GO:0030421)
0.2	2.8	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.2	4.1	GO:0007019	microtubule depolymerization(GO:0007019)
0.2	0.2	GO:1903975	regulation of glial cell migration(GO:1903975)
0.2	1.5	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.2	1.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	4.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.7	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	1.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.1	2.0	GO:0097352	autophagosome maturation(GO:0097352)
0.1	0.1	GO:0071866	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.1	0.8	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	0.4	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.5	GO:0046113	nucleobase catabolic process(GO:0046113)
0.1	0.4	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.4	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.1	0.4	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	4.0	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	0.6	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	2.1	GO:0010259	multicellular organism aging(GO:0010259)
0.1	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	2.6	GO:0006813	potassium ion transport(GO:0006813)
0.1	0.1	GO:0009189	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.1	GO:0071280	cellular response to copper ion(GO:0071280)
0.1	0.2	GO:1901724	positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.1	0.1	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.1	0.4	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.7	GO:0016074	snoRNA metabolic process(GO:0016074)
0.1	0.3	GO:0002254	kinin cascade(GO:0002254)
0.1	0.7	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.1	0.2	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.1	0.2	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.1	0.1	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1	0.2	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.1	1.6	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.2	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.7	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.7	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.3	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.4	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1	0.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.2	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1	0.8	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	0.2	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	1.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.2	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1	0.2	GO:2000209	regulation of anoikis(GO:2000209)
0.1	0.3	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.1	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	0.4	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1	0.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.1	0.2	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.1	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.2	GO:0070268	cornification(GO:0070268)
0.1	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.1	0.1	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.1	0.1	GO:0010446	response to alkaline pH(GO:0010446)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.4	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.0	0.0	GO:0038001	paracrine signaling(GO:0038001)
0.0	0.2	GO:0046348	amino sugar catabolic process(GO:0046348)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.4	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.2	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	1.3	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.2	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0033083	regulation of immature T cell proliferation(GO:0033083)
0.0	0.1	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.2	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0006598	polyamine catabolic process(GO:0006598)
0.0	0.0	GO:0006241	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.6	40.7	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
8.1	8.1	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
7.7	77.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
7.2	50.7	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
7.2	35.8	GO:0097433	dense body(GO:0097433)
7.1	42.4	GO:0016012	sarcoglycan complex(GO:0016012)
5.7	22.9	GO:0033010	paranodal junction(GO:0033010)
5.1	15.3	GO:0072534	perineuronal net(GO:0072534)
4.9	24.6	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
4.9	14.6	GO:1990761	growth cone lamellipodium(GO:1990761)
4.7	51.9	GO:0043194	axon initial segment(GO:0043194)
4.7	23.4	GO:0044294	dendritic growth cone(GO:0044294)
4.3	59.9	GO:0043196	varicosity(GO:0043196)
4.2	63.1	GO:0048786	presynaptic active zone(GO:0048786)
4.1	99.2	GO:0044295	axonal growth cone(GO:0044295)
4.0	36.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
4.0	32.0	GO:0042788	polysomal ribosome(GO:0042788)
3.9	15.6	GO:1990696	USH2 complex(GO:1990696)
3.9	19.4	GO:0044300	cerebellar mossy fiber(GO:0044300)
3.5	173.9	GO:0042734	presynaptic membrane(GO:0042734)
3.5	35.1	GO:0030673	axolemma(GO:0030673)
3.3	19.6	GO:0032584	growth cone membrane(GO:0032584)
3.2	22.7	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
3.1	9.4	GO:0097441	basilar dendrite(GO:0097441)
3.1	34.2	GO:0032426	stereocilium tip(GO:0032426)
3.1	18.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
3.1	12.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.8	8.4	GO:0048179	activin receptor complex(GO:0048179)
2.8	11.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
2.7	8.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
2.6	5.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
2.6	10.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
2.5	7.6	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
2.5	2.5	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.4	16.8	GO:0035253	ciliary rootlet(GO:0035253)
2.3	9.3	GO:0043083	synaptic cleft(GO:0043083)
2.3	9.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
2.3	30.1	GO:0031045	dense core granule(GO:0031045)
2.2	4.5	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
2.2	8.8	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.1	6.2	GO:0033269	internode region of axon(GO:0033269)
2.0	2.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
2.0	7.9	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.0	50.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
1.9	76.2	GO:0043198	dendritic shaft(GO:0043198)
1.8	5.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
1.8	28.1	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.7	5.0	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.7	18.3	GO:0043656	host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
1.7	5.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.6	9.6	GO:0071437	invadopodium(GO:0071437)
1.6	17.6	GO:0042555	MCM complex(GO:0042555)
1.6	4.8	GO:0005594	collagen type IX trimer(GO:0005594)
1.6	1.6	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.5	12.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.4	4.3	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.4	2.9	GO:0044326	dendritic spine neck(GO:0044326)
1.4	7.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
1.4	7.0	GO:0032009	early phagosome(GO:0032009)
1.4	4.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.4	5.5	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.3	7.7	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.3	7.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
1.3	11.3	GO:0030061	mitochondrial crista(GO:0030061)
1.2	17.4	GO:0031527	filopodium membrane(GO:0031527)
1.2	1.2	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
1.2	12.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
1.2	12.1	GO:0060077	inhibitory synapse(GO:0060077)
1.1	6.8	GO:0001674	female germ cell nucleus(GO:0001674)
1.1	4.4	GO:1990716	axonemal central apparatus(GO:1990716)
1.1	102.3	GO:0045211	postsynaptic membrane(GO:0045211)
1.1	16.5	GO:0032809	neuronal cell body membrane(GO:0032809)
1.1	62.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
1.1	8.7	GO:0030991	intraciliary transport particle A(GO:0030991)
1.1	161.4	GO:0060076	excitatory synapse(GO:0060076)
1.1	2.1	GO:0032280	symmetric synapse(GO:0032280)
1.0	1.0	GO:0044615	nuclear pore nuclear basket(GO:0044615)
1.0	23.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
1.0	4.0	GO:0051286	cell tip(GO:0051286)
1.0	4.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
1.0	58.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.9	5.6	GO:0097449	astrocyte projection(GO:0097449)
0.9	2.8	GO:1990075	periciliary membrane compartment(GO:1990075)
0.9	5.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.9	2.6	GO:0055087	Ski complex(GO:0055087)
0.8	1.6	GO:0033263	CORVET complex(GO:0033263)
0.8	4.0	GO:0045098	type III intermediate filament(GO:0045098)
0.8	2.4	GO:0070939	Dsl1p complex(GO:0070939)
0.8	2.3	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.8	0.8	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.8	2.3	GO:0016600	flotillin complex(GO:0016600)
0.8	8.3	GO:0017119	Golgi transport complex(GO:0017119)
0.7	3.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.7	14.6	GO:0044447	axoneme part(GO:0044447)
0.7	3.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.7	0.7	GO:0005593	FACIT collagen trimer(GO:0005593)
0.6	1.9	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.6	1.3	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.6	1.9	GO:0005899	insulin receptor complex(GO:0005899)
0.6	84.5	GO:0031225	anchored component of membrane(GO:0031225)
0.6	1.8	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.6	1.8	GO:0097427	microtubule bundle(GO:0097427)
0.6	3.6	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.6	28.0	GO:0008021	synaptic vesicle(GO:0008021)
0.6	13.6	GO:0034451	centriolar satellite(GO:0034451)
0.6	7.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.6	2.8	GO:0000796	condensin complex(GO:0000796)
0.6	6.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.5	2.2	GO:0070695	FHF complex(GO:0070695)
0.5	0.5	GO:0044393	microspike(GO:0044393)
0.5	6.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5	12.5	GO:0032420	stereocilium(GO:0032420)
0.5	6.3	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.5	4.6	GO:0002116	semaphorin receptor complex(GO:0002116)
0.5	5.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.5	0.9	GO:0071797	LUBAC complex(GO:0071797)
0.5	2.3	GO:0061617	MICOS complex(GO:0061617)
0.5	0.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.4	2.7	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.4	24.5	GO:0043195	terminal bouton(GO:0043195)
0.4	1.3	GO:1990909	Wnt signalosome(GO:1990909)
0.4	1.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4	7.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.4	0.9	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.4	10.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.4	1.6	GO:1990246	uniplex complex(GO:1990246)
0.4	6.4	GO:0042101	T cell receptor complex(GO:0042101)
0.4	5.5	GO:0070382	exocytic vesicle(GO:0070382)
0.4	60.7	GO:0030424	axon(GO:0030424)
0.4	2.3	GO:0071986	Ragulator complex(GO:0071986)
0.4	4.1	GO:0045277	respiratory chain complex IV(GO:0045277)
0.4	0.4	GO:0044299	C-fiber(GO:0044299)
0.4	4.9	GO:0070822	Sin3-type complex(GO:0070822)
0.4	1.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4	2.2	GO:0031415	NatA complex(GO:0031415)
0.4	11.9	GO:0098794	postsynapse(GO:0098794)
0.4	22.7	GO:0030426	growth cone(GO:0030426)
0.4	1.1	GO:1990130	Iml1 complex(GO:1990130)
0.3	3.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.3	0.7	GO:1990923	PET complex(GO:1990923)
0.3	9.0	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3	1.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.3	1.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.3	0.9	GO:0043511	inhibin complex(GO:0043511)
0.3	33.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.3	1.9	GO:0000137	Golgi cis cisterna(GO:0000137)
0.3	23.3	GO:0043025	neuronal cell body(GO:0043025)
0.3	0.9	GO:0043293	apoptosome(GO:0043293)
0.3	2.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	3.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.3	1.9	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3	1.9	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	8.0	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3	9.1	GO:0005871	kinesin complex(GO:0005871)
0.2	0.7	GO:0042583	chromaffin granule(GO:0042583)
0.2	0.7	GO:0097543	ciliary inversin compartment(GO:0097543)
0.2	0.9	GO:0071546	pi-body(GO:0071546)
0.2	1.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.2	0.4	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2	0.6	GO:0000802	transverse filament(GO:0000802)
0.2	1.5	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2	1.0	GO:0071547	piP-body(GO:0071547)
0.2	1.2	GO:0002177	manchette(GO:0002177)
0.2	1.4	GO:0097546	ciliary base(GO:0097546)
0.2	0.7	GO:0044530	supraspliceosomal complex(GO:0044530)
0.2	0.7	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2	0.5	GO:0030689	Noc complex(GO:0030689)
0.2	0.5	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2	0.2	GO:0097386	glial cell projection(GO:0097386)
0.1	0.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	1.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.7	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	1.8	GO:0030914	STAGA complex(GO:0030914)
0.1	8.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	6.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.6	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.7	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	1.2	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.8	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	0.9	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	0.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.5	GO:0005869	dynactin complex(GO:0005869)
0.1	0.5	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.3	GO:0044292	dendrite terminus(GO:0044292)
0.1	1.3	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	0.6	GO:0098793	presynapse(GO:0098793)
0.1	2.6	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.4	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.1	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	1.1	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.4	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	1.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	4.2	GO:0043005	neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
36.8	110.4	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
15.5	46.6	GO:0097109	neuroligin family protein binding(GO:0097109)
10.5	31.5	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
10.0	30.0	GO:0070699	type II activin receptor binding(GO:0070699)
9.9	49.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
9.2	36.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
8.9	26.8	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
8.7	26.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
8.2	24.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
7.4	22.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
7.3	36.6	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
7.2	28.9	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
7.2	36.0	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
7.0	21.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
6.6	26.3	GO:0032051	clathrin light chain binding(GO:0032051)
6.3	44.1	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
6.0	6.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
5.8	17.5	GO:0004351	glutamate decarboxylase activity(GO:0004351)
5.7	17.2	GO:0050816	phosphothreonine binding(GO:0050816)
5.5	21.8	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
5.1	20.5	GO:0008502	melatonin receptor activity(GO:0008502)
5.0	15.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
4.9	34.3	GO:0008046	axon guidance receptor activity(GO:0008046)
4.9	43.7	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
4.5	31.6	GO:0003680	AT DNA binding(GO:0003680)
4.4	13.3	GO:0097108	hedgehog family protein binding(GO:0097108)
4.4	8.7	GO:0045503	dynein light chain binding(GO:0045503)
4.2	25.4	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
4.2	38.0	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
4.1	12.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
4.0	23.9	GO:0004385	guanylate kinase activity(GO:0004385)
3.8	7.7	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
3.6	10.8	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.5	10.4	GO:0016842	amidine-lyase activity(GO:0016842)
3.4	3.4	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
3.4	6.8	GO:0019871	sodium channel inhibitor activity(GO:0019871)
3.3	20.0	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.3	13.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
3.3	13.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
3.3	16.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.1	43.7	GO:0008179	adenylate cyclase binding(GO:0008179)
3.1	18.6	GO:0034190	apolipoprotein receptor binding(GO:0034190)
3.1	12.4	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.9	8.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.9	8.7	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
2.8	24.9	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
2.7	13.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
2.7	8.2	GO:0016015	morphogen activity(GO:0016015)
2.7	2.7	GO:0030350	iron-responsive element binding(GO:0030350)
2.7	10.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.7	18.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
2.7	8.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
2.6	13.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
2.6	15.8	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
2.5	7.5	GO:0008184	glycogen phosphorylase activity(GO:0008184)
2.5	47.4	GO:0017075	syntaxin-1 binding(GO:0017075)
2.5	9.9	GO:0005042	netrin receptor activity(GO:0005042)
2.5	9.8	GO:0070878	primary miRNA binding(GO:0070878)
2.4	56.1	GO:0045499	chemorepellent activity(GO:0045499)
2.4	4.8	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
2.4	14.4	GO:0016421	CoA carboxylase activity(GO:0016421)
2.4	7.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
2.4	9.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.3	18.8	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
2.3	11.6	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
2.3	4.6	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
2.3	11.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.3	9.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.2	6.7	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.1	25.4	GO:0050811	GABA receptor binding(GO:0050811)
2.1	48.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
2.1	14.5	GO:0046790	virion binding(GO:0046790)
2.1	4.1	GO:0097016	L27 domain binding(GO:0097016)
2.0	8.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
2.0	6.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
2.0	10.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
1.9	9.6	GO:0048495	Roundabout binding(GO:0048495)
1.9	5.7	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
1.9	5.7	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.9	9.5	GO:0070883	pre-miRNA binding(GO:0070883)
1.9	7.5	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.8	7.3	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.8	10.6	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.7	19.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.7	8.6	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
1.7	6.8	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
1.7	6.8	GO:1904288	BAT3 complex binding(GO:1904288)
1.7	8.5	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
1.7	6.8	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.6	3.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
1.6	31.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.6	32.7	GO:0003785	actin monomer binding(GO:0003785)
1.6	6.5	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
1.6	4.9	GO:0051880	G-quadruplex DNA binding(GO:0051880)
1.6	1.6	GO:0038191	neuropilin binding(GO:0038191)
1.6	1.6	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.6	9.3	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.5	17.0	GO:0017065	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
1.5	18.4	GO:0004000	adenosine deaminase activity(GO:0004000)
1.5	21.5	GO:0045295	gamma-catenin binding(GO:0045295)
1.5	4.6	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
1.5	4.5	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.5	8.7	GO:0032027	myosin light chain binding(GO:0032027)
1.4	29.0	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.4	5.8	GO:0004127	cytidylate kinase activity(GO:0004127)
1.4	7.1	GO:0004565	beta-galactosidase activity(GO:0004565)
1.4	14.1	GO:0008066	glutamate receptor activity(GO:0008066)
1.4	7.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
1.4	5.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.4	5.6	GO:0097001	ceramide binding(GO:0097001)
1.4	1.4	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
1.4	8.3	GO:0015198	oligopeptide transporter activity(GO:0015198)
1.4	5.5	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
1.4	2.7	GO:0016361	activin receptor activity, type I(GO:0016361)
1.4	1.4	GO:0005502	11-cis retinal binding(GO:0005502)
1.3	12.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
1.3	13.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
1.3	2.7	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
1.3	4.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.3	18.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
1.3	17.8	GO:0004890	GABA-A receptor activity(GO:0004890)
1.3	19.0	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.3	3.8	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.3	18.8	GO:0016805	dipeptidase activity(GO:0016805)
1.3	7.5	GO:0032050	clathrin heavy chain binding(GO:0032050)
1.2	2.5	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
1.2	3.7	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
1.2	9.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.2	5.9	GO:0042609	CD4 receptor binding(GO:0042609)
1.2	23.5	GO:0005540	hyaluronic acid binding(GO:0005540)
1.2	20.8	GO:0071837	HMG box domain binding(GO:0071837)
1.1	6.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.1	4.6	GO:0043495	protein anchor(GO:0043495)
1.1	3.4	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.1	1.1	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
1.1	21.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.1	2.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
1.1	3.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.1	4.3	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.1	18.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
1.1	10.8	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
1.1	32.8	GO:0070888	E-box binding(GO:0070888)
1.1	3.2	GO:0035939	microsatellite binding(GO:0035939)
1.0	2.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
1.0	8.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0	5.1	GO:0002054	nucleobase binding(GO:0002054)
1.0	6.2	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
1.0	3.9	GO:0033142	progesterone receptor binding(GO:0033142)
1.0	2.9	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
1.0	24.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.0	13.6	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.0	1.0	GO:0048408	epidermal growth factor binding(GO:0048408)
1.0	1.0	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
1.0	2.9	GO:0016149	translation release factor activity, codon specific(GO:0016149)
1.0	8.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.9	19.0	GO:0030332	cyclin binding(GO:0030332)
0.9	4.7	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.9	2.8	GO:0000403	Y-form DNA binding(GO:0000403)
0.9	6.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.9	2.8	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.9	1.8	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.9	5.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.9	1.8	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.9	4.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.9	3.5	GO:1990932	5.8S rRNA binding(GO:1990932)
0.9	5.3	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.9	19.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.9	11.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.9	29.9	GO:0017095	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.9	9.4	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.8	3.4	GO:0034235	GPI anchor binding(GO:0034235)
0.8	5.9	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8	10.0	GO:0035198	miRNA binding(GO:0035198)
0.8	14.6	GO:0031420	alkali metal ion binding(GO:0031420)
0.8	2.4	GO:0005148	prolactin receptor binding(GO:0005148)
0.8	5.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.8	10.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.8	3.9	GO:0004985	opioid receptor activity(GO:0004985)
0.8	1.6	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.8	2.3	GO:0051425	PTB domain binding(GO:0051425)
0.8	6.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.8	8.5	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.8	16.2	GO:0005537	mannose binding(GO:0005537)
0.8	12.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.8	1.5	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.7	10.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.7	1.5	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.7	4.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.7	10.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	3.6	GO:0070728	leucine binding(GO:0070728)
0.7	7.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.7	5.6	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.7	3.4	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.7	3.3	GO:0001515	opioid peptide activity(GO:0001515)
0.7	2.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.7	2.7	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.7	14.6	GO:0017091	AU-rich element binding(GO:0017091)
0.7	8.6	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.6	3.2	GO:0036310	annealing helicase activity(GO:0036310)
0.6	2.5	GO:0004969	histamine receptor activity(GO:0004969)
0.6	0.6	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6	1.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6	3.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.6	2.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6	1.2	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.6	1.8	GO:0016882	cyclo-ligase activity(GO:0016882)
0.6	1.8	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.6	16.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.6	5.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.6	1.7	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.6	1.7	GO:0004359	glutaminase activity(GO:0004359)
0.6	1.7	GO:0098821	BMP receptor activity(GO:0098821)
0.6	2.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.6	5.0	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.6	16.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.5	5.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.5	10.9	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.5	1.6	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5	11.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	10.0	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.5	5.8	GO:0031404	chloride ion binding(GO:0031404)
0.5	1.5	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.5	14.0	GO:0019894	kinesin binding(GO:0019894)
0.5	2.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.5	2.8	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.5	1.4	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.5	1.4	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.5	0.9	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.5	0.5	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.5	0.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.4	1.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.4	1.3	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.4	1.8	GO:0043842	Kdo transferase activity(GO:0043842)
0.4	1.3	GO:0032190	acrosin binding(GO:0032190)
0.4	7.8	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.4	4.7	GO:0031005	filamin binding(GO:0031005)
0.4	2.1	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.4	1.3	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4	0.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.4	2.9	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.4	4.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.4	2.1	GO:0071723	lipopeptide binding(GO:0071723)
0.4	1.7	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.4	1.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4	0.8	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.4	4.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.4	2.4	GO:0019957	C-C chemokine binding(GO:0019957)
0.4	1.6	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4	1.2	GO:0089720	caspase binding(GO:0089720)
0.4	5.4	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.4	3.5	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4	0.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4	1.9	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4	1.5	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.4	3.7	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.4	1.5	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.4	1.4	GO:0004849	uridine kinase activity(GO:0004849)
0.4	6.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.4	1.4	GO:0034056	estrogen response element binding(GO:0034056)
0.4	12.5	GO:0051018	protein kinase A binding(GO:0051018)
0.4	1.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.4	1.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.3	0.7	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.3	0.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.3	1.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	0.7	GO:0051185	coenzyme transporter activity(GO:0051185)
0.3	0.3	GO:0030249	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.3	1.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.3	8.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.3	6.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	3.5	GO:0005522	profilin binding(GO:0005522)
0.3	0.3	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.3	1.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3	6.0	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.3	0.3	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.3	0.9	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.3	1.2	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.3	3.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.3	1.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.3	7.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.3	2.9	GO:0035173	histone kinase activity(GO:0035173)
0.3	6.4	GO:0044688	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3	2.9	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3	2.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	0.9	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.3	2.3	GO:0031386	protein tag(GO:0031386)
0.3	0.9	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3	1.7	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.3	1.1	GO:0051434	BH3 domain binding(GO:0051434)
0.3	3.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	0.8	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.3	0.8	GO:0008495	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.3	1.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3	0.8	GO:0032767	copper-dependent protein binding(GO:0032767)
0.2	0.7	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2	1.7	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2	0.7	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2	2.5	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2	0.9	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2	0.7	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.2	1.1	GO:0042301	phosphate ion binding(GO:0042301)
0.2	5.8	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.2	1.7	GO:0034784	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.2	0.2	GO:0051378	serotonin binding(GO:0051378)
0.2	4.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.2	0.6	GO:0004946	bombesin receptor activity(GO:0004946)
0.2	2.2	GO:0001671	ATPase activator activity(GO:0001671)
0.2	1.8	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.2	7.5	GO:0017022	myosin binding(GO:0017022)
0.2	0.8	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.2	1.0	GO:0016937	short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.2	4.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	3.8	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	0.9	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2	0.9	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	3.8	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.2	0.3	GO:0042895	antibiotic transporter activity(GO:0042895)
0.2	0.5	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2	0.3	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2	5.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	0.3	GO:2001070	starch binding(GO:2001070)
0.2	0.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	0.8	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.2	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.6	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	5.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.4	GO:0031493	nucleosomal histone binding(GO:0031493)
0.1	1.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	1.5	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	1.2	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.4	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	1.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.9	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.1	11.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	2.0	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.7	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.1	0.1	GO:0001030	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.6	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	1.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	5.0	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.1	0.1	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
0.1	0.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	1.7	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.1	0.4	GO:0034584	piRNA binding(GO:0034584)
0.1	2.8	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	3.3	GO:0008907	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.1	0.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	1.0	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.2	GO:0019961	interferon binding(GO:0019961)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.4	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.4	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	3.1	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.1	0.4	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1	0.7	GO:0000146	microfilament motor activity(GO:0000146)
0.1	0.7	GO:0009881	photoreceptor activity(GO:0009881)
0.1	0.1	GO:0035870	dITP diphosphatase activity(GO:0035870)
0.1	0.4	GO:0033691	sialic acid binding(GO:0033691)
0.1	1.8	GO:0043022	ribosome binding(GO:0043022)
0.1	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	2.5	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	0.7	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.2	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.8	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.4	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.5	GO:0005186	pheromone activity(GO:0005186)
0.0	15.0	GO:0005549	odorant binding(GO:0005549)
0.0	0.5	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.6	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.6	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.0	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.0	17.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
3.7	117.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
2.6	2.6	PID IGF1 PATHWAY	IGF1 pathway
2.3	7.0	ST G ALPHA I PATHWAY	G alpha i Pathway
2.2	8.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.7	1.7	PID REELIN PATHWAY	Reelin signaling pathway
1.5	3.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.4	12.9	PID S1P S1P4 PATHWAY	S1P4 pathway
1.0	13.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.0	15.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.0	1.9	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.9	33.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.9	3.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.8	20.2	ST ADRENERGIC	Adrenergic Pathway
0.8	20.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.8	24.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.8	1.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.7	24.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.7	24.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.5	11.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.5	2.8	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.5	5.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	0.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.4	3.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	3.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	23.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.4	55.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4	13.8	PID SHP2 PATHWAY	SHP2 signaling
0.3	11.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	1.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.3	4.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	5.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	5.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	4.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.2	0.9	SIG CHEMOTAXIS	Genes related to chemotaxis
0.2	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	0.5	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	46.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
3.6	83.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
3.4	24.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
3.2	54.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.8	22.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
2.8	58.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
2.7	29.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
2.7	37.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
2.5	10.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
2.5	35.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.5	5.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
2.4	18.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
2.1	16.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
2.1	51.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.0	30.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.9	31.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
1.9	36.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.9	24.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
1.8	5.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.7	15.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
1.7	11.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
1.7	21.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.7	72.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
1.6	19.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.5	1.5	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
1.3	41.1	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
1.3	9.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.3	24.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.2	4.8	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
1.2	33.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.1	13.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
1.1	9.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.0	8.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.9	10.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.9	8.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.9	10.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9	8.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.8	16.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.8	5.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.8	7.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.8	14.7	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.8	20.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.8	2.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.8	3.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.7	9.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.7	0.7	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.7	2.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.7	25.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.7	0.7	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.7	21.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.7	4.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.6	6.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.6	7.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.6	8.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.6	6.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.6	1.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.6	7.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.5	2.7	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.5	7.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.5	3.7	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.5	6.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	1.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.5	5.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.5	2.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.5	6.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5	1.4	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.4	6.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.4	5.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.4	0.4	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.4	3.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.4	15.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.4	8.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4	6.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.4	6.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	7.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3	3.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	4.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.3	1.7	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.3	5.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.3	10.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	6.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	1.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.3	6.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	8.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.2	1.5	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	11.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.2	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	2.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2	4.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	1.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.2	1.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.2	1.8	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	2.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	5.7	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	3.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	1.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.1	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.1	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.4	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress

Results for Nkx6-1_Evx1_Hesx1

Z-value: 5.66

Motif logo

Transcription factors associated with Nkx6-1_Evx1_Hesx1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nkx6-1_Evx1_Hesx1 motif across conditions

Conditions sorted by the z-value of the Nkx6-1_Evx1_Hesx1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: