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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Nr6a1

Z-value: 0.98

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Transcription factors associated with Nr6a1

Gene Symbol	Gene ID	Gene Info
Nr6a1 Ensembl NCBI MGI UniProt	ENSMUSG00000063972.7	nuclear receptor subfamily 6, group A, member 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_38739566_38739717	Nr6a1	823	0.485625	0.49	1.3e-04	Click!
chr2_38784488_38784649	Nr6a1	48	0.957925	-0.20	1.5e-01	Click!
chr2_38925778_38926094	Nr6a1	281	0.838462	0.05	7.4e-01	Click!
chr2_38926098_38926539	Nr6a1	43	0.954949	0.04	7.6e-01	Click!
chr2_38785249_38785400	Nr6a1	213	0.893798	-0.04	7.6e-01	Click!

Activity of the Nr6a1 motif across conditions

Conditions sorted by the z-value of the Nr6a1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_110050502_110051534	4.71	Dmrta2	doublesex and mab-3 related transcription factor like family A2	72965	0.11
chr9_124439906_124440949	4.68	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	441	0.79
chr4_82304607_82304811	3.62	n-R5s188	nuclear encoded rRNA 5S 188	134701	0.05
chr1_81520769_81521201	3.59	Gm37210	predicted gene, 37210	1356	0.55
chr1_81588038_81588300	3.09	Gm6198	predicted gene 6198	30686	0.22
chr4_98108669_98109025	2.98	Gm12691	predicted gene 12691	37752	0.2
chr10_76732571_76732722	2.96	Gm48276	predicted gene, 48276	2373	0.25
chr11_117336202_117336679	2.90	Septin9	septin 9	4012	0.23
chr6_119409613_119410171	2.88	Adipor2	adiponectin receptor 2	7583	0.21
chr12_3236518_3237725	2.77	Rab10os	RAB10, member RAS oncogene family, opposite strand	510	0.74
chr13_40994999_40995221	2.54	Pak1ip1	PAK1 interacting protein 1	5913	0.12
chrX_60147349_60147500	2.43	Mcf2	mcf.2 transforming sequence	219	0.95
chr4_82505225_82505396	2.43	Nfib	nuclear factor I/B	0	0.98
chr10_11044838_11044994	2.38	Gm48406	predicted gene, 48406	9000	0.23
chr17_49472723_49472906	2.30	Mocs1	molybdenum cofactor synthesis 1	20530	0.2
chr18_11234055_11234212	2.19	Gata6	GATA binding protein 6	175086	0.03
chr12_95695278_95696175	2.13	Flrt2	fibronectin leucine rich transmembrane protein 2	369	0.86
chr11_55022601_55023592	2.12	Anxa6	annexin A6	10319	0.16
chr13_63230991_63231626	2.10	Aopep	aminopeptidase O	8721	0.11
chr12_108003961_108004329	2.10	Bcl11b	B cell leukemia/lymphoma 11B	543	0.85
chr4_119815571_119815722	2.09	Hivep3	human immunodeficiency virus type I enhancer binding protein 3	1151	0.61
chr19_10071333_10071499	2.06	Fads2	fatty acid desaturase 2	229	0.9
chr16_63747767_63748162	2.02	Gm22769	predicted gene, 22769	430	0.91
chr7_16119631_16120684	1.99	Kptn	kaptin	62	0.96
chr13_69482238_69482460	1.93	Gm48676	predicted gene, 48676	31651	0.13
chr7_79535477_79536145	1.90	Gm35040	predicted gene, 35040	232	0.85
chr17_74879880_74880031	1.86	Ttc27	tetratricopeptide repeat domain 27	18034	0.17
chr2_58787447_58787599	1.81	Upp2	uridine phosphorylase 2	22198	0.18
chr1_90093233_90093384	1.79	Iqca	IQ motif containing with AAA domain	3164	0.29
chr9_58355790_58355941	1.77	Tbc1d21	TBC1 domain family, member 21	14504	0.15
chr4_32196712_32196887	1.73	Gm11929	predicted gene 11929	10349	0.2
chr5_114175447_114176205	1.72	Acacb	acetyl-Coenzyme A carboxylase beta	80	0.96
chr17_56809917_56810952	1.72	Rfx2	regulatory factor X, 2 (influences HLA class II expression)	20505	0.11
chr10_110927477_110927905	1.70	Csrp2	cysteine and glycine-rich protein 2	3510	0.19
chr6_119487122_119487339	1.68	Fbxl14	F-box and leucine-rich repeat protein 14	7562	0.21
chr1_57846936_57847100	1.67	Spats2l	spermatogenesis associated, serine-rich 2-like	1447	0.5
chr10_107752299_107752727	1.66	Ptprq	protein tyrosine phosphatase, receptor type, Q	32462	0.23
chr17_25462548_25463080	1.65	Tekt4	tektin 4	8199	0.11
chr8_102596538_102596950	1.60	Cdh11	cadherin 11	40575	0.15
chr11_111215086_111215415	1.60	Gm11675	predicted gene 11675	60850	0.15
chr3_9704898_9705332	1.58	Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	113	0.97
chr2_115660293_115660477	1.58	Mir1951	microRNA 1951	21660	0.23
chr1_79858099_79859256	1.57	Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	19	0.98
chr6_134994369_134994520	1.56	Apold1	apolipoprotein L domain containing 1	12726	0.13
chr11_120311318_120311784	1.56	Bahcc1	BAH domain and coiled-coil containing 1	21758	0.08
chr8_10754564_10754760	1.51	Gm39129	predicted gene, 39129	15772	0.13
chr4_141425494_141426465	1.49	Hspb7	heat shock protein family, member 7 (cardiovascular)	5200	0.1
chr6_93648670_93648869	1.49	Gm7812	predicted gene 7812	1456	0.55
chr5_112825174_112825344	1.47	1700095B10Rik	RIKEN cDNA 1700095B10 gene	31927	0.16
chr12_10017131_10017323	1.47	Gm5182	predicted gene 5182	134915	0.05
chr4_76461421_76461659	1.46	Gm42303	predicted gene, 42303	10309	0.22
chr16_89924625_89924841	1.45	Tiam1	T cell lymphoma invasion and metastasis 1	5748	0.31
chr15_71917480_71917631	1.45	Col22a1	collagen, type XXII, alpha 1	19939	0.24
chr7_4516460_4516712	1.45	Tnnt1	troponin T1, skeletal, slow	204	0.84
chr13_39823948_39824404	1.43	A230103O09Rik	RIKEN cDNA A230103O09 gene	178	0.94
chr1_75559272_75559776	1.40	Slc4a3	solute carrier family 4 (anion exchanger), member 3	7815	0.11
chr17_56467426_56468397	1.40	Ptprs	protein tyrosine phosphatase, receptor type, S	5695	0.16
chr8_126659831_126660263	1.36	Irf2bp2	interferon regulatory factor 2 binding protein 2	66061	0.11
chr17_88954148_88954333	1.34	Gm9407	predicted gene 9407	97618	0.08
chr8_6456655_6456806	1.34	Gm44844	predicted gene 44844	18986	0.29
chr4_116016940_116018214	1.33	Faah	fatty acid amide hydrolase	98	0.95
chr14_32321782_32322361	1.33	Ogdhl	oxoglutarate dehydrogenase-like	52	0.96
chr3_9833533_9834642	1.32	Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	408	0.84
chr9_95257001_95257349	1.29	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9	135489	0.04
chr14_12716331_12716619	1.29	Gm48266	predicted gene, 48266	54075	0.13
chr1_74054406_74054750	1.28	Tns1	tensin 1	17421	0.19
chr1_73992293_73993185	1.27	Tns1	tensin 1	2633	0.33
chr8_127438974_127439332	1.26	Pard3	par-3 family cell polarity regulator	8593	0.3
chr11_69559283_69560047	1.25	Efnb3	ephrin B3	540	0.54
chr17_57276298_57276514	1.24	Vav1	vav 1 oncogene	2694	0.18
chr10_18468496_18468770	1.24	Nhsl1	NHS-like 1	1255	0.55
chr5_125163793_125164061	1.24	Ncor2	nuclear receptor co-repressor 2	15126	0.21
chr4_114676951_114677102	1.23	Gm28864	predicted gene 28864	3686	0.25
chr1_194030707_194030867	1.23	Gm21362	predicted gene, 21362	163778	0.04
chr6_114396692_114396879	1.22	Hrh1	histamine receptor H1	1151	0.61
chr5_125216280_125216449	1.21	Ncor2	nuclear receptor co-repressor 2	37145	0.14
chr2_90917239_90918445	1.21	Ptpmt1	protein tyrosine phosphatase, mitochondrial 1	15	0.71
chr17_80803081_80803318	1.19	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	74714	0.09
chr8_34163517_34163668	1.18	Mir6395	microRNA 6395	3120	0.14
chr13_55362078_55363351	1.15	Lman2	lectin, mannose-binding 2	69	0.95
chr8_44708951_44709102	1.15	Gm26089	predicted gene, 26089	107193	0.07
chr1_127352497_127352650	1.15	Gm23370	predicted gene, 23370	20760	0.15
chr7_112222783_112223211	1.15	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	2859	0.36
chr15_62230752_62231120	1.14	Pvt1	Pvt1 oncogene	8333	0.25
chr8_84712009_84712803	1.14	Nfix	nuclear factor I/X	1662	0.21
chr13_51408491_51409234	1.13	S1pr3	sphingosine-1-phosphate receptor 3	223	0.94
chr2_150645270_150645552	1.11	Acss1	acyl-CoA synthetase short-chain family member 1	7296	0.13
chr3_115822572_115822723	1.11	Dph5	diphthamide biosynthesis 5	65190	0.08
chr11_9048085_9048240	1.11	Gm11992	predicted gene 11992	432	0.67
chr9_102692932_102693123	1.09	4930533D04Rik	RIKEN cDNA 4930533D04 gene	142	0.94
chr13_53205183_53205803	1.09	Ror2	receptor tyrosine kinase-like orphan receptor 2	70165	0.11
chr14_61327668_61327972	1.08	Gm5461	predicted gene 5461	2010	0.21
chr2_56983190_56983369	1.08	Gm13527	predicted gene 13527	96469	0.08
chr8_48224421_48225088	1.08	Gm32842	predicted gene, 32842	46231	0.16
chr9_62436154_62436349	1.06	Coro2b	coronin, actin binding protein, 2B	7001	0.24
chr16_77296088_77296239	1.06	Gm31258	predicted gene, 31258	9397	0.2
chr3_127662316_127662467	1.04	Alpk1	alpha-kinase 1	23949	0.1
chr10_116243379_116243665	1.04	Ptprb	protein tyrosine phosphatase, receptor type, B	32001	0.15
chrX_71051287_71051495	1.04	Mamld1	mastermind-like domain containing 1	1135	0.58
chr14_70530107_70530260	1.04	Lgi3	leucine-rich repeat LGI family, member 3	502	0.65
chr18_15405119_15405460	1.03	Aqp4	aquaporin 4	1531	0.37
chr7_68744740_68744917	1.01	Arrdc4	arrestin domain containing 4	4360	0.26
chr1_176949345_176949641	1.01	Gm15423	predicted gene 15423	16782	0.13
chr17_23960426_23960630	1.01	Sbpl	spermine binding protein-like	5254	0.08
chr3_107517078_107517566	1.00	Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	5	0.98
chr10_79681206_79682337	1.00	Cdc34	cell division cycle 34	424	0.63
chr11_108241078_108241308	1.00	Gm11655	predicted gene 11655	59343	0.12
chr8_128025780_128025931	0.98	Mir21c	microRNA 21c	252370	0.02
chr11_66487857_66488008	0.97	Shisa6	shisa family member 6	14882	0.27
chr8_20384730_20385046	0.96	Gm7807	predicted gene 7807	3807	0.22
chr10_34563895_34564051	0.96	Frk	fyn-related kinase	80441	0.1
chr5_30920760_30922186	0.95	Khk	ketohexokinase	42	0.93
chr11_118247752_118249318	0.95	Cyth1	cytohesin 1	25	0.97
chr18_44754207_44754358	0.95	Mcc	mutated in colorectal cancers	29624	0.17
chr2_114048115_114048266	0.95	Actc1	actin, alpha, cardiac muscle 1	4697	0.18
chr12_54288052_54288203	0.94	Gm47552	predicted gene, 47552	28888	0.13
chr8_128263663_128263945	0.94	Mir21c	microRNA 21c	14421	0.27
chr5_151142402_151142622	0.94	Stard13	StAR-related lipid transfer (START) domain containing 13	14969	0.24
chr12_11436805_11437388	0.92	Vsnl1	visinin-like 1	483	0.68
chr7_66955436_66955938	0.92	Gm44755	predicted gene 44755	6231	0.22
chr15_27630977_27631306	0.92	Otulin	OTU deubiquitinase with linear linkage specificity	448	0.79
chr16_77239477_77239636	0.92	Mir99ahg	Mir99a and Mirlet7c-1 host gene (non-protein coding)	3237	0.3
chr5_105793170_105793576	0.91	Rps15a-ps5	ribosomal protein S15A, pseudogene 5	4340	0.19
chr3_83997060_83997321	0.91	Tmem131l	transmembrane 131 like	28962	0.2
chr7_139516348_139516610	0.91	Inpp5a	inositol polyphosphate-5-phosphatase A	180	0.96
chr12_104897006_104897472	0.91	Gm28875	predicted gene 28875	29450	0.13
chr5_64580424_64580579	0.90	Gm42566	predicted gene 42566	15682	0.11
chr16_34902354_34902568	0.90	Mylk	myosin, light polypeptide kinase	2206	0.34
chr19_27607032_27607183	0.90	Gm50101	predicted gene, 50101	94599	0.08
chr2_75000578_75000751	0.89	n-R5s198	nuclear encoded rRNA 5S 198	65150	0.09
chr19_20567101_20567252	0.89	C730002L08Rik	RIKEN cDNA C730002L08 gene	14846	0.19
chr2_38425074_38425256	0.88	Gm13589	predicted gene 13589	1163	0.43
chr11_77875222_77875543	0.88	Pipox	pipecolic acid oxidase	7304	0.15
chr2_17839635_17839891	0.88	Gm13323	predicted gene 13323	41779	0.17
chr3_134105217_134105368	0.88	Gm26691	predicted gene, 26691	3227	0.26
chr2_52050954_52051105	0.86	Tnfaip6	tumor necrosis factor alpha induced protein 6	13020	0.19
chr8_10040892_10041043	0.86	Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	9649	0.16
chr17_25433197_25433617	0.86	Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	129	0.93
chr15_83037870_83038112	0.86	Nfam1	Nfat activating molecule with ITAM motif 1	4685	0.16
chr6_51513838_51514067	0.85	Snx10	sorting nexin 10	9949	0.19
chr10_83692278_83692464	0.85	1500009L16Rik	RIKEN cDNA 1500009L16 gene	30494	0.15
chr14_84446496_84447465	0.84	Pcdh17	protocadherin 17	1527	0.47
chr11_3132475_3133419	0.84	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	3060	0.17
chr9_77496504_77496829	0.83	Lrrc1	leucine rich repeat containing 1	35778	0.13
chr8_104602084_104602428	0.83	Pdp2	pyruvate dehyrogenase phosphatase catalytic subunit 2	10805	0.09
chr8_20257716_20258061	0.83	6820431F20Rik	RIKEN cDNA 6820431F20 gene	25378	0.2
chr12_15566567_15566816	0.83	Gm17915	predicted gene, 17915	14563	0.23
chr3_28264071_28264435	0.83	Tnik	TRAF2 and NCK interacting kinase	610	0.76
chr6_89008167_89008318	0.83	4933427D06Rik	RIKEN cDNA 4933427D06 gene	57559	0.1
chr3_52685799_52685950	0.82	Gm22798	predicted gene, 22798	36881	0.16
chr2_54215819_54215970	0.82	Gm13505	predicted gene 13505	24675	0.22
chr3_107793294_107794069	0.81	Gm43233	predicted gene 43233	11825	0.12
chr16_17277832_17278420	0.81	Tmem191c	transmembrane protein 191C	525	0.65
chr15_73246575_73246818	0.81	1700085D07Rik	RIKEN cDNA 1700085D07 gene	2850	0.22
chr2_68452494_68452645	0.80	Stk39	serine/threonine kinase 39	19371	0.19
chr15_55043599_55043825	0.80	Taf2	TATA-box binding protein associated factor 2	2454	0.24
chr1_93063621_93064051	0.79	Kif1a	kinesin family member 1A	4922	0.16
chr4_64437737_64437968	0.79	Gm23950	predicted gene, 23950	6878	0.33
chr2_104008253_104008404	0.79	Fbxo3	F-box protein 3	19393	0.11
chr19_7196543_7197592	0.79	Otub1	OTU domain, ubiquitin aldehyde binding 1	3397	0.16
chr11_112873093_112873244	0.79	4933434M16Rik	RIKEN cDNA 4933434M16 gene	47989	0.15
chr9_121299534_121299685	0.79	Trak1	trafficking protein, kinesin binding 1	1780	0.28
chr5_103387516_103387737	0.79	5430427N15Rik	RIKEN cDNA 5430427N15 gene	30928	0.13
chr6_108570853_108571723	0.78	Gm16433	predicted gene 16433	5700	0.17
chr2_7519605_7519756	0.78	Celf2	CUGBP, Elav-like family member 2	10117	0.23
chr10_81128986_81129587	0.78	Map2k2	mitogen-activated protein kinase kinase 2	671	0.44
chr10_122870324_122870475	0.78	Ppm1h	protein phosphatase 1H (PP2C domain containing)	24969	0.19
chr6_72584180_72584499	0.78	Elmod3	ELMO/CED-12 domain containing 3	10682	0.09
chr11_35948423_35948795	0.77	Wwc1	WW, C2 and coiled-coil domain containing 1	31918	0.18
chr9_91353887_91354086	0.77	A730094K22Rik	RIKEN cDNA A730094K22 gene	3033	0.14
chr1_65129934_65130085	0.77	D630023F18Rik	RIKEN cDNA D630023F18 gene	6795	0.12
chr15_82255387_82255538	0.76	1500009C09Rik	RIKEN cDNA 1500009C09 gene	561	0.55
chr15_31989572_31989923	0.76	Gm49285	predicted gene, 49285	60204	0.14
chr4_94752503_94752932	0.76	Tek	TEK receptor tyrosine kinase	13199	0.21
chr4_6840020_6840184	0.76	Tox	thymocyte selection-associated high mobility group box	150381	0.04
chr6_84410254_84410424	0.76	Gm10445	predicted gene 10445	13499	0.26
chr2_178118970_178119469	0.76	Phactr3	phosphatase and actin regulator 3	40	0.98
chr13_72134510_72134727	0.76	Irx1	Iroquois homeobox 1	170895	0.03
chr2_166403117_166403659	0.75	Gm14268	predicted gene 14268	5201	0.25
chr9_34984399_34984565	0.75	Gm23702	predicted gene, 23702	24463	0.16
chr17_81538552_81538703	0.75	Gm11096	predicted gene 11096	96864	0.08
chr13_95443458_95443716	0.75	Crhbp	corticotropin releasing hormone binding protein	1244	0.41
chr14_79204811_79205110	0.75	Gm4632	predicted gene 4632	5770	0.17
chr2_181156387_181156681	0.75	Eef1a2	eukaryotic translation elongation factor 1 alpha 2	480	0.69
chr3_141943276_141943438	0.74	Bmpr1b	bone morphogenetic protein receptor, type 1B	11834	0.29
chr17_70753475_70753647	0.74	5031415H12Rik	RIKEN cDNA 5031415H12 gene	2021	0.31
chr14_47186589_47186864	0.74	Gch1	GTP cyclohydrolase 1	2687	0.15
chr8_104076802_104077176	0.74	Gm8748	predicted gene 8748	5840	0.17
chr11_63338410_63338561	0.74	Gm12286	predicted gene 12286	25174	0.21
chr5_26991582_26992107	0.73	Gm16057	predicted gene 16057	15777	0.25
chr10_56980420_56980571	0.73	Gm36827	predicted gene, 36827	1737	0.46
chr13_60173703_60173877	0.72	Gm48488	predicted gene, 48488	2892	0.21
chr8_20593052_20593376	0.72	Gm21112	predicted gene, 21112	3827	0.2
chr2_26458386_26459048	0.72	Gm13568	predicted gene 13568	1573	0.21
chr12_82935466_82935659	0.72	1700085C21Rik	RIKEN cDNA 1700085C21 gene	3593	0.28
chr4_125194460_125194614	0.71	1700041M05Rik	RIKEN cDNA 1700041M05 gene	34060	0.15
chr4_63742174_63742328	0.71	Tnfsf15	tumor necrosis factor (ligand) superfamily, member 15	2862	0.29
chr17_34549976_34550127	0.71	Btnl7-ps	butyrophilin-like 7, pseudogene	2400	0.11
chrX_162363227_162363562	0.71	Gm15204	predicted gene 15204	11798	0.27
chr3_157882081_157882268	0.71	Gm6520	predicted gene 6520	6700	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	2.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.8	3.1	GO:0060486	Clara cell differentiation(GO:0060486)
0.7	2.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.5	1.5	GO:0042628	mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.3	1.7	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.2	0.7	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	0.7	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.2	1.3	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.2	1.4	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.2	0.7	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.2	0.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.2	0.6	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2	1.1	GO:0034651	cortisol biosynthetic process(GO:0034651)
0.1	0.6	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.9	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	0.4	GO:0032344	regulation of aldosterone metabolic process(GO:0032344)
0.1	0.4	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	0.4	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	0.4	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.5	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.1	0.5	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.4	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.1	1.0	GO:0032328	alanine transport(GO:0032328)
0.1	1.0	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.3	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.4	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.7	GO:0016198	axon choice point recognition(GO:0016198)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.4	GO:0003383	apical constriction(GO:0003383)
0.1	0.3	GO:0035993	deltoid tuberosity development(GO:0035993)
0.1	0.4	GO:0070295	renal water absorption(GO:0070295)
0.1	0.7	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.1	0.7	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.4	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.3	GO:0030035	microspike assembly(GO:0030035)
0.1	0.5	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.1	0.5	GO:1903799	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.5	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	1.0	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	1.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	3.8	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1	0.2	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1	0.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.4	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.1	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.1	0.3	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.2	GO:0021586	pons maturation(GO:0021586)
0.1	0.2	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1	0.2	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.6	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.2	GO:0086064	cell communication by electrical coupling involved in cardiac conduction(GO:0086064)
0.1	0.4	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1	0.3	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.2	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.1	0.1	GO:0097503	sialylation(GO:0097503)
0.1	0.4	GO:0071321	cellular response to cGMP(GO:0071321)
0.1	0.1	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.1	0.2	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.2	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	0.2	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.3	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.2	GO:0031296	B cell costimulation(GO:0031296)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.6	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.3	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.0	0.5	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.2	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.2	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.4	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0072034	renal vesicle induction(GO:0072034) ureter morphogenesis(GO:0072197)
0.0	0.1	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.2	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.1	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.2	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.6	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.1	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.1	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.1	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.3	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0098596	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.1	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.5	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.0	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0	0.1	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.9	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	2.4	GO:0050868	negative regulation of T cell activation(GO:0050868)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.4	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.3	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.2	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.2	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.0	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.0	0.4	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.2	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
0.0	0.2	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.2	GO:0048070	regulation of developmental pigmentation(GO:0048070)
0.0	0.2	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.8	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0002666	positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:1902566	regulation of eosinophil degranulation(GO:0043309) regulation of eosinophil activation(GO:1902566)
0.0	0.2	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:1902855	regulation of nonmotile primary cilium assembly(GO:1902855)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.5	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.2	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.2	GO:0042473	outer ear morphogenesis(GO:0042473)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:0043307	eosinophil activation(GO:0043307)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.0	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.5	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0	0.1	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0032596	protein transport into membrane raft(GO:0032596)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	1.4	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.1	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.3	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.0	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0043586	tongue development(GO:0043586)
0.0	0.0	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.1	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.0	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0021550	medulla oblongata development(GO:0021550)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.0	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.0	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.2	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.0	0.4	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:1904861	excitatory synapse assembly(GO:1904861)
0.0	0.0	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.0	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	1.3	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.2	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.0	GO:0032202	telomere assembly(GO:0032202)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.0	GO:0008078	mesodermal cell migration(GO:0008078)
0.0	0.0	GO:0006971	hypotonic response(GO:0006971)
0.0	0.1	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.0	GO:0061054	dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0	0.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.0	0.0	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.0	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0060179	male mating behavior(GO:0060179)
0.0	0.0	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.0	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.0	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	1.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.2	0.7	GO:0071797	LUBAC complex(GO:0071797)
0.2	0.3	GO:0044393	microspike(GO:0044393)
0.2	1.3	GO:0005861	troponin complex(GO:0005861)
0.2	0.5	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.4	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1	0.6	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.4	GO:0033269	internode region of axon(GO:0033269)
0.1	0.5	GO:0016589	NURF complex(GO:0016589)
0.1	0.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.4	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.2	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.3	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	1.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.4	GO:0060091	kinocilium(GO:0060091)
0.0	0.3	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.8	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:1990357	terminal web(GO:1990357)
0.0	1.0	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.5	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.2	GO:0031672	A band(GO:0031672)
0.0	0.4	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.0	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0009374	biotin binding(GO:0009374)
0.3	1.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3	1.3	GO:0031014	troponin T binding(GO:0031014)
0.3	0.9	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.3	2.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3	3.8	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.3	1.6	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.2	0.7	GO:0055100	adiponectin binding(GO:0055100)
0.2	0.9	GO:0042731	PH domain binding(GO:0042731)
0.2	0.8	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2	0.7	GO:0004969	histamine receptor activity(GO:0004969)
0.2	0.5	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2	0.5	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.9	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1	0.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	1.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.0	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.4	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1	3.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.3	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.3	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.1	0.8	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.4	GO:0015288	porin activity(GO:0015288)
0.1	1.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1	0.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	1.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.4	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.3	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.2	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	0.4	GO:0018644	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	0.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.4	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	1.0	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.6	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.5	GO:0008969	phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) inositol-4,5-bisphosphate 5-phosphatase activity(GO:0030487) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.9	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.4	GO:0005537	mannose binding(GO:0005537)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0046030	inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.3	GO:0052712	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.1	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.0	0.2	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.7	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	1.7	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	0.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.4	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	3.2	PID SHP2 PATHWAY	SHP2 signaling
0.1	1.0	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.3	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	1.1	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	1.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	3.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	2.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.8	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	1.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.5	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling

Results for Nr6a1

Z-value: 0.98

Motif logo

Transcription factors associated with Nr6a1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Nr6a1 motif across conditions

Conditions sorted by the z-value of the Nr6a1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: