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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Pitx2_Otx2

Z-value: 1.79

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Transcription factors associated with Pitx2_Otx2

Gene Symbol	Gene ID	Gene Info
Pitx2 Ensembl NCBI MGI UniProt	ENSMUSG00000028023.10	paired-like homeodomain transcription factor 2
Otx2 Ensembl NCBI MGI UniProt	ENSMUSG00000021848.9	orthodenticle homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr14_48667515_48667667	Otx2	53	0.925627	0.77	7.3e-12	Click!
chr14_48666180_48666367	Otx2	752	0.428731	0.71	1.2e-09	Click!
chr14_48665335_48665486	Otx2	111	0.920994	0.66	3.5e-08	Click!
chr14_48665025_48665185	Otx2	1	0.947670	0.63	3.0e-07	Click!
chr3_129200004_129200202	Pitx2	134	0.957304	0.73	3.8e-10	Click!
chr3_129199429_129199931	Pitx2	198	0.936788	0.69	7.3e-09	Click!
chr3_129204151_129204986	Pitx2	621	0.696278	0.68	9.4e-09	Click!
chr3_129200277_129200428	Pitx2	383	0.846222	0.68	1.4e-08	Click!
chr3_129205035_129205234	Pitx2	1187	0.438961	0.66	3.9e-08	Click!

Activity of the Pitx2_Otx2 motif across conditions

Conditions sorted by the z-value of the Pitx2_Otx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_20616739_20617639	73.37	Gm16090	predicted gene 16090	48071	0.1
chr18_20621651_20622570	66.70	Gm16090	predicted gene 16090	43150	0.11
chr18_20625060_20625736	49.81	Gm16090	predicted gene 16090	39862	0.12
chr18_20625915_20626381	20.97	Gm16090	predicted gene 16090	39112	0.12
chr18_20615543_20616002	19.05	Gm16090	predicted gene 16090	49488	0.1
chr8_47004297_47004459	10.64	Gm45600	predicted gene 45600	9799	0.17
chr18_20624320_20624587	9.50	Gm16090	predicted gene 16090	40807	0.12
chr10_81383963_81384933	9.05	Dohh	deoxyhypusine hydroxylase/monooxygenase	11	0.48
chr11_17460047_17460676	8.05	Gm12015	predicted gene 12015	161942	0.03
chr8_47003593_47003771	7.81	Gm45600	predicted gene 45600	10495	0.17
chr12_29526481_29526772	7.75	Myt1l	myelin transcription factor 1-like	1758	0.41
chr7_35344847_35345230	7.05	Rhpn2	rhophilin, Rho GTPase binding protein 2	10708	0.14
chr1_85279771_85280739	6.96	Gm16026	predicted pseudogene 16026	5148	0.14
chr18_20618481_20618693	6.95	Gm16090	predicted gene 16090	46673	0.11
chr17_23586174_23586500	6.92	Zfp13	zinc finger protein 13	105	0.91
chr18_20627927_20628180	6.89	Gm16090	predicted gene 16090	37207	0.12
chr13_57603228_57603418	6.69	Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	304264	0.01
chr8_47003974_47004154	6.62	Gm45600	predicted gene 45600	10113	0.17
chr2_127521161_127522051	6.59	Kcnip3	Kv channel interacting protein 3, calsenilin	236	0.88
chr12_71601536_71601687	6.35	9630002D21Rik	RIKEN cDNA 9630002D21 gene	23646	0.21
chr14_12821852_12822433	6.29	Cadps	Ca2+-dependent secretion activator	903	0.65
chr11_43548063_43548966	5.97	Ccnjl	cyclin J-like	19268	0.13
chr4_110050502_110051534	5.95	Dmrta2	doublesex and mab-3 related transcription factor like family A2	72965	0.11
chr2_32625098_32626151	5.92	Ak1	adenylate kinase 1	186	0.86
chr14_19042458_19042951	5.91	Gm48781	predicted gene, 48781	480	0.71
chr8_47003312_47003463	5.73	Gm45600	predicted gene 45600	10790	0.17
chr4_87651182_87651681	5.70	Gm12604	predicted gene 12604	70642	0.13
chr11_100527857_100528615	5.65	Acly	ATP citrate lyase	236	0.86
chr12_5274464_5274897	5.53	Klhl29	kelch-like 29	16701	0.22
chr7_61939801_61940302	5.49	Mir344-2	microRNA 344-2	55	0.95
chr8_125254170_125254832	5.32	Gm16237	predicted gene 16237	27178	0.23
chr19_22518652_22518803	5.32	Gm27151	predicted gene 27151	69862	0.11
chr18_20626425_20626742	5.21	Gm16090	predicted gene 16090	38677	0.12
chr7_96718538_96719200	5.19	Tenm4	teneurin transmembrane protein 4	59065	0.11
chr16_44632721_44633371	5.18	Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	74149	0.08
chr9_78880202_78880613	5.10	Gm47498	predicted gene, 47498	56376	0.1
chr5_112213704_112214228	5.05	Gm26953	predicted gene, 26953	1495	0.29
chr6_36818994_36819767	5.04	Ptn	pleiotrophin	9160	0.28
chr13_28948317_28948483	5.04	Sox4	SRY (sex determining region Y)-box 4	5313	0.23
chr13_93839171_93839651	5.02	Mir5624	microRNA 5624	48634	0.11
chr3_68202202_68202415	4.98	Gm10292	predicted gene 10292	130888	0.05
chr19_59542145_59542347	4.97	Gm18161	predicted gene, 18161	1795	0.38
chrX_143543266_143543620	4.92	Pak3	p21 (RAC1) activated kinase 3	24745	0.25
chr11_92135029_92135209	4.90	Gm22702	predicted gene, 22702	110706	0.08
chr1_76490736_76491111	4.87	Gm17751	predicted gene, 17751	1790	0.42
chr12_86887931_86888776	4.79	Irf2bpl	interferon regulatory factor 2 binding protein-like	3555	0.23
chr14_86063145_86063329	4.67	Gm32729	predicted gene, 32729	109686	0.06
chr16_54992065_54992216	4.64	Gm22977	predicted gene, 22977	19709	0.28
chr1_96346717_96347057	4.61	Gm37076	predicted gene, 37076	33645	0.18
chr3_83273897_83274205	4.58	Gm38096	predicted gene, 38096	129351	0.05
chr4_114779259_114779410	4.56	Gm12830	predicted gene 12830	42388	0.14
chr12_7029729_7029880	4.55	Gm46311	predicted gene, 46311	62844	0.16
chr14_34969154_34969501	4.53	Mir346	microRNA 346	74718	0.11
chr12_3238767_3239202	4.53	Rab10os	RAB10, member RAS oncogene family, opposite strand	2373	0.24
chr7_126288627_126288778	4.53	Sbk1	SH3-binding kinase 1	2378	0.19
chr2_49718537_49718899	4.46	Kif5c	kinesin family member 5C	3849	0.28
chr7_62232164_62232315	4.45	Gm9801	predicted gene 9801	22760	0.21
chr7_66060127_66060635	4.45	Snrpa1	small nuclear ribonucleoprotein polypeptide A'	43	0.96
chr6_122491488_122491885	4.44	Rimklb	ribosomal modification protein rimK-like family member B	5181	0.14
chr10_37250963_37251350	4.42	4930543K20Rik	RIKEN cDNA 4930543K20 gene	12592	0.25
chr18_20619091_20619258	4.42	Gm16090	predicted gene 16090	46086	0.11
chr14_66319706_66319909	4.40	Gm41183	predicted gene, 41183	21422	0.13
chr7_96832704_96833057	4.38	Gm44633	predicted gene 44633	14574	0.14
chr1_23098558_23098709	4.36	Ppp1r14bl	protein phosphatase 1, regulatory inhibitor subunit 14B like	3620	0.31
chr9_47071101_47071252	4.35	Gm4791	predicted gene 4791	72435	0.1
chr18_22850734_22850918	4.34	Nol4	nucleolar protein 4	72	0.99
chr12_102468744_102469733	4.31	Golga5	golgi autoantigen, golgin subfamily a, 5	46	0.97
chr1_161380092_161380398	4.31	Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	15164	0.21
chr14_75455687_75456060	4.29	Siah3	siah E3 ubiquitin protein ligase family member 3	109	0.97
chr3_51095889_51096111	4.29	Gm38246	predicted gene, 38246	7660	0.2
chr6_86051794_86051956	4.25	Add2	adducin 2 (beta)	373	0.79
chr9_41578468_41578685	4.24	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	918	0.39
chr17_45873055_45873569	4.24	4930542M03Rik	RIKEN cDNA 4930542M03 gene	8140	0.17
chr9_102692609_102692931	4.23	4930533D04Rik	RIKEN cDNA 4930533D04 gene	115	0.95
chr14_14350947_14351733	4.21	Il3ra	interleukin 3 receptor, alpha chain	1719	0.23
chr4_126648482_126648847	4.18	Gm12933	predicted gene 12933	16590	0.13
chr11_103721925_103722258	4.17	Gm11642	predicted gene 11642	1859	0.26
chr18_3116148_3116568	4.15	Vmn1r238	vomeronasal 1 receptor, 238	7054	0.16
chr10_81289386_81289717	4.14	Tjp3	tight junction protein 3	1664	0.13
chr15_35758712_35758863	4.11	Gm18994	predicted gene, 18994	25183	0.15
chr10_34316564_34316763	4.09	Nt5dc1	5'-nucleotidase domain containing 1	2980	0.17
chr6_47239363_47240145	4.09	Cntnap2	contactin associated protein-like 2	4633	0.33
chr7_25316512_25317661	4.09	Megf8	multiple EGF-like-domains 8	78	0.94
chr16_86838461_86838612	4.09	Gm25715	predicted gene, 25715	6934	0.21
chr1_168046925_168047110	4.08	Gm20711	predicted gene 20711	42878	0.2
chr18_24529850_24530706	4.04	Rprd1a	regulation of nuclear pre-mRNA domain containing 1A	74	0.97
chr2_109693106_109694421	4.04	Bdnf	brain derived neurotrophic factor	200	0.94
chr14_22649708_22649874	4.04	Lrmda	leucine rich melanocyte differentiation associated	53278	0.15
chr3_32817066_32817811	4.04	Usp13	ubiquitin specific peptidase 13 (isopeptidase T-3)	108	0.97
chr12_26802654_26802851	4.03	4933409F18Rik	RIKEN cDNA 4933409F18 gene	32107	0.23
chr10_21145268_21145562	4.01	Gm26577	predicted gene, 26577	321	0.81
chr14_119857299_119857740	4.01	4930404K13Rik	RIKEN cDNA 4930404K13 gene	58541	0.13
chr1_182823776_182823944	4.00	Susd4	sushi domain containing 4	58965	0.11
chr1_164590281_164590783	3.99	D630023O14Rik	RIKEN cDNA D630023O14 gene	15077	0.17
chr6_122495966_122496190	3.99	Rimklb	ribosomal modification protein rimK-like family member B	2683	0.18
chr19_53449312_53449723	3.99	Mirt1	myocardial infarction associated transcript 1	1974	0.25
chr1_93100941_93101460	3.99	Kif1a	kinesin family member 1A	622	0.65
chr1_81594178_81594459	3.98	Gm6198	predicted gene 6198	36835	0.2
chr14_17722808_17722982	3.98	Gm48320	predicted gene, 48320	48227	0.17
chr1_70442796_70442968	3.95	Gm38272	predicted gene, 38272	129971	0.05
chr18_20627203_20627433	3.95	Gm16090	predicted gene 16090	37942	0.12
chr5_135725743_135726117	3.94	Por	P450 (cytochrome) oxidoreductase	202	0.89
chr12_117257705_117257898	3.92	Mir153	microRNA 153	6984	0.29
chr16_57302914_57303208	3.91	Tmem30c	transmembrane protein 30C	10196	0.14
chr7_3314248_3314438	3.91	Prkcg	protein kinase C, gamma	8999	0.08
chr8_40634456_40635069	3.89	Mtmr7	myotubularin related protein 7	3	0.98
chr9_56830372_56830523	3.88	Odf3l1	outer dense fiber of sperm tails 3-like 1	21516	0.12
chr3_51097482_51097714	3.86	Gm38246	predicted gene, 38246	6062	0.21
chr6_119674568_119674747	3.85	Erc1	ELKS/RAB6-interacting/CAST family member 1	52552	0.15
chr15_8605889_8606074	3.83	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	37266	0.13
chr12_105336106_105336602	3.82	Tunar	Tcl1 upstream neural differentiation associated RNA	240	0.93
chr13_29273638_29274140	3.82	Gm11364	predicted gene 11364	37269	0.22
chr7_6382694_6383817	3.82	Zfp28	zinc finger protein 28	40	0.94
chr1_178856348_178856609	3.78	Kif26b	kinesin family member 26B	58040	0.13
chr9_41582201_41582428	3.77	Mir125b-1	microRNA 125b-1	388	0.42
chr18_20618066_20618220	3.76	Gm16090	predicted gene 16090	47117	0.11
chr16_90459106_90459640	3.76	Hunk	hormonally upregulated Neu-associated kinase	2524	0.3
chr11_20112252_20113564	3.76	Actr2	ARP2 actin-related protein 2	1	0.98
chr12_83044975_83045325	3.76	Rgs6	regulator of G-protein signaling 6	1840	0.38
chr1_119051267_119051418	3.75	Gli2	GLI-Kruppel family member GLI2	1997	0.35
chr16_69577439_69577590	3.75	4930428D20Rik	RIKEN cDNA 4930428D20 gene	222867	0.02
chr8_12328207_12328374	3.74	Gm33175	predicted gene, 33175	8810	0.16
chr4_141048548_141049235	3.74	Crocc	ciliary rootlet coiled-coil, rootletin	4770	0.13
chr16_46982388_46982568	3.74	Gm6912	predicted gene 6912	91720	0.1
chr1_18308203_18308365	3.74	Defb41	defensin beta 41	43146	0.14
chr7_34596890_34597065	3.74	Gm44837	predicted gene 44837	40735	0.11
chr7_92984793_92985009	3.73	Gm31663	predicted gene, 31663	2849	0.25
chr18_20628591_20628850	3.73	Gm16090	predicted gene 16090	36540	0.13
chr18_20621175_20621448	3.72	Gm16090	predicted gene 16090	43949	0.11
chr13_113917716_113918082	3.72	Arl15	ADP-ribosylation factor-like 15	123277	0.05
chr8_114295236_114295423	3.71	4933408N05Rik	RIKEN cDNA 4933408N05 gene	56150	0.14
chr5_111922904_111923242	3.70	Gm42488	predicted gene 42488	21162	0.23
chr1_157938110_157938282	3.70	Gm38256	predicted gene, 38256	2189	0.46
chr6_91348397_91348588	3.67	Wnt7a	wingless-type MMTV integration site family, member 7A	16579	0.16
chr10_13108625_13108836	3.66	Plagl1	pleiomorphic adenoma gene-like 1	4735	0.24
chr2_109579120_109579313	3.65	Gm20638	predicted gene 20638	93950	0.07
chr13_83720072_83720262	3.65	C130071C03Rik	RIKEN cDNA C130071C03 gene	1214	0.37
chr18_14844486_14844862	3.65	Gm21055	predicted gene, 21055	14006	0.21
chr2_51066696_51066895	3.63	Rnd3	Rho family GTPase 3	82299	0.1
chr8_96864637_96865011	3.62	Gm24132	predicted gene, 24132	208695	0.02
chr13_84752343_84752734	3.62	Gm26913	predicted gene, 26913	61597	0.15
chr5_77207847_77208140	3.61	Spink2	serine peptidase inhibitor, Kazal type 2	3212	0.19
chr8_54992339_54992525	3.61	Gm45265	predicted gene 45265	12853	0.14
chr3_80913126_80913366	3.61	Glrb	glycine receptor, beta subunit	282	0.93
chr17_6860510_6860926	3.60	Mir692-1	microRNA 692-1	34619	0.11
chr1_57218512_57218908	3.60	BC055402	cDNA sequence BC055402	3717	0.29
chr2_113828734_113829247	3.59	Scg5	secretogranin V	131	0.96
chr8_8232331_8232493	3.59	A630009H07Rik	RIKEN cDNA A630009H07 gene	102665	0.06
chr16_45722680_45722901	3.58	Tagln3	transgelin 3	1818	0.27
chr13_78191875_78192156	3.57	Nr2f1	nuclear receptor subfamily 2, group F, member 1	1572	0.29
chr9_41834587_41834738	3.57	Gm35940	predicted gene, 35940	19058	0.15
chr4_100776154_100776315	3.55	Cachd1	cache domain containing 1	441	0.9
chr15_45453906_45454087	3.55	AC099642.1	Endogenous retrovirus group K member 10 (ERVK-10) pseudogene	292545	0.01
chr13_107767262_107767617	3.55	Zswim6	zinc finger SWIM-type containing 6	19157	0.22
chr1_169485704_169485889	3.53	Gm5265	predicted pseudogene 5265	31927	0.17
chr10_37626746_37626910	3.52	Gm48172	predicted gene, 48172	174148	0.03
chr1_81520769_81521201	3.51	Gm37210	predicted gene, 37210	1356	0.55
chr18_38214552_38214897	3.51	2010320O07Rik	RIKEN cDNA 2010320O07 gene	1020	0.39
chr4_52643943_52644118	3.50	Toporsl	topoisomerase I binding, arginine/serine-rich like	36824	0.18
chr12_27076467_27076625	3.50	Gm9866	predicted gene 9866	38449	0.22
chr8_26678010_26678194	3.47	Gm32098	predicted gene, 32098	9796	0.18
chr11_32002527_32003111	3.47	Nsg2	neuron specific gene family member 2	2317	0.33
chr5_89883765_89884131	3.47	Adamts3	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3	614	0.82
chr12_80061788_80062584	3.47	Gm36660	predicted gene, 36660	19248	0.14
chr4_140070081_140070517	3.47	Gm13027	predicted gene 13027	61578	0.1
chr7_48803519_48803712	3.46	Gm45041	predicted gene 45041	7313	0.16
chr1_132211975_132212170	3.44	Lemd1	LEM domain containing 1	8220	0.12
chr10_78727029_78727441	3.43	Casp14	caspase 14	8941	0.11
chr3_105530220_105530411	3.43	Gm43847	predicted gene 43847	27408	0.18
chr9_82812387_82812538	3.43	Irak1bp1	interleukin-1 receptor-associated kinase 1 binding protein 1	17078	0.25
chr9_14031471_14031650	3.43	1700019J19Rik	RIKEN cDNA 1700019J19 gene	58060	0.11
chr6_47231711_47231866	3.43	Cntnap2	contactin associated protein-like 2	12599	0.29
chr10_91858784_91859239	3.43	Gm31592	predicted gene, 31592	29818	0.24
chr14_100374770_100375216	3.41	Gm26367	predicted gene, 26367	43490	0.15
chr16_95596975_95597306	3.41	Erg	ETS transcription factor	10547	0.27
chr18_20626775_20626931	3.40	Gm16090	predicted gene 16090	38407	0.12
chr17_72194935_72195301	3.40	Gm19183	predicted gene, 19183	61140	0.15
chr16_32156836_32156987	3.39	Nrros	negative regulator of reactive oxygen species	8546	0.12
chr2_93957285_93957562	3.39	Gm13889	predicted gene 13889	222	0.91
chr13_94575931_94576376	3.39	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	33850	0.14
chr14_75876392_75876718	3.39	Snora31	small nucleolar RNA, H/ACA box 31	28650	0.12
chr14_68361503_68361660	3.39	Gm31227	predicted gene, 31227	100050	0.07
chr3_90606271_90606454	3.39	S100a4	S100 calcium binding protein A4	1451	0.18
chr15_58190488_58190639	3.38	Gm15943	predicted gene 15943	23912	0.12
chr19_59457383_59457662	3.38	Emx2	empty spiracles homeobox 2	850	0.44
chr12_17753065_17753234	3.37	Hpcal1	hippocalcin-like 1	24923	0.19
chr7_99267195_99268129	3.37	Map6	microtubule-associated protein 6	173	0.76
chr4_13743823_13743979	3.37	Runx1t1	RUNX1 translocation partner 1	465	0.89
chr10_78464271_78465733	3.37	Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase	27	0.93
chr10_98354561_98354717	3.37	Gm8633	predicted gene 8633	2765	0.36
chr3_123811268_123811432	3.37	Gm15400	predicted gene 15400	50023	0.14
chr7_79504714_79505014	3.36	Mir9-3	microRNA 9-3	400	0.7
chr13_67451013_67451769	3.36	Zfp874a	zinc finger protein 874a	189	0.57
chr9_40320937_40321820	3.36	Gramd1b	GRAM domain containing 1B	458	0.69
chr3_99938984_99939135	3.36	Spag17	sperm associated antigen 17	53642	0.14
chr9_41805841_41806047	3.36	AC160966.1	novel transcript	261	0.72
chr10_23718242_23718393	3.36	Snora33	small nucleolar RNA, H/ACA box 33	67158	0.07
chr10_95618546_95618735	3.35	Gm33336	predicted gene, 33336	13599	0.13
chr2_73573013_73573289	3.35	Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	7187	0.15
chr9_23062142_23062343	3.34	Bmper	BMP-binding endothelial regulator	160834	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	29.2	GO:0070327	thyroid hormone transport(GO:0070327)
4.2	21.0	GO:0003164	His-Purkinje system development(GO:0003164)
2.5	10.2	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
2.4	2.4	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
2.0	6.1	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
2.0	5.9	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
1.9	5.6	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.7	5.1	GO:0006172	ADP biosynthetic process(GO:0006172)
1.5	4.4	GO:0060166	olfactory pit development(GO:0060166)
1.4	5.5	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
1.4	4.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
1.3	6.7	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.2	3.7	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
1.2	3.7	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
1.2	2.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
1.2	4.8	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.2	3.6	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.2	3.5	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
1.2	4.7	GO:0016199	axon midline choice point recognition(GO:0016199)
1.1	3.4	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.1	4.5	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
1.1	3.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.1	4.4	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
1.1	3.3	GO:0032289	central nervous system myelin formation(GO:0032289)
1.1	3.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
1.0	7.3	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
1.0	3.1	GO:0021564	vagus nerve development(GO:0021564)
1.0	5.0	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.9	0.9	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.9	3.8	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
0.9	5.5	GO:0060174	limb bud formation(GO:0060174)
0.9	4.5	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.9	2.7	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.9	2.6	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.9	6.0	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.8	2.5	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.8	4.2	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.8	2.5	GO:0033505	floor plate morphogenesis(GO:0033505)
0.8	2.5	GO:0030242	pexophagy(GO:0030242)
0.8	2.4	GO:1903375	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.8	2.3	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
0.7	1.5	GO:0060594	mammary gland specification(GO:0060594)
0.7	1.5	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.7	2.2	GO:0021843	substrate-independent telencephalic tangential migration(GO:0021826) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.7	3.0	GO:0030091	protein repair(GO:0030091)
0.7	5.7	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.7	1.4	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.7	3.6	GO:0019695	choline metabolic process(GO:0019695)
0.7	2.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.7	0.7	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.7	5.6	GO:0046069	cGMP catabolic process(GO:0046069)
0.7	8.2	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.7	1.4	GO:0072319	clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.7	2.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.7	2.0	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.7	0.7	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.7	2.0	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.6	1.3	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.6	3.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.6	1.8	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.6	1.8	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.6	1.8	GO:0030070	insulin processing(GO:0030070)
0.6	3.6	GO:0031223	auditory behavior(GO:0031223)
0.6	3.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.6	1.2	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.6	1.2	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.6	1.8	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.6	0.6	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.6	3.5	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.6	1.2	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.6	2.9	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6	1.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.6	2.3	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.6	0.6	GO:0086068	Purkinje myocyte action potential(GO:0086017) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.6	4.5	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.6	1.7	GO:0089700	protein kinase D signaling(GO:0089700)
0.6	1.1	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.5	1.6	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.5	0.5	GO:0021825	substrate-dependent cerebral cortex tangential migration(GO:0021825)
0.5	47.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.5	1.6	GO:0046959	habituation(GO:0046959)
0.5	2.7	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.5	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.5	1.6	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.5	1.6	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.5	0.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.5	2.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.5	1.5	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.5	2.1	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5	1.0	GO:0060066	oviduct development(GO:0060066)
0.5	7.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.5	1.5	GO:0060178	regulation of exocyst localization(GO:0060178)
0.5	2.0	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.5	1.5	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.5	1.5	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.5	1.5	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.5	1.5	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5	1.9	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.5	1.5	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.5	3.4	GO:0042118	endothelial cell activation(GO:0042118)
0.5	1.9	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.5	1.4	GO:0072092	ureteric bud invasion(GO:0072092)
0.5	1.4	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.5	2.4	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.5	1.9	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.5	1.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5	0.5	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.5	2.3	GO:0061591	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.5	1.4	GO:0060437	lung growth(GO:0060437)
0.5	0.9	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.5	1.4	GO:1902075	cellular response to salt(GO:1902075)
0.5	7.8	GO:0016082	synaptic vesicle priming(GO:0016082)
0.5	1.4	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.5	1.4	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.4	2.7	GO:0015074	DNA integration(GO:0015074)
0.4	5.3	GO:0016486	peptide hormone processing(GO:0016486)
0.4	0.4	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.4	4.4	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.4	0.9	GO:2000668	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.4	1.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.3	GO:0007525	somatic muscle development(GO:0007525)
0.4	0.9	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.4	1.3	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.4	1.3	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4	1.3	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.4	1.7	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4	1.3	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.4	0.4	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.4	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4	1.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.4	0.8	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.4	1.3	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.4	0.8	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.4	0.8	GO:0071873	response to norepinephrine(GO:0071873)
0.4	1.3	GO:0001927	exocyst assembly(GO:0001927)
0.4	1.7	GO:0051697	protein delipidation(GO:0051697)
0.4	2.5	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4	1.7	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.4	3.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4	1.2	GO:0061743	motor learning(GO:0061743)
0.4	1.6	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.4	0.8	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4	0.8	GO:0014028	notochord formation(GO:0014028)
0.4	0.4	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.4	1.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.4	1.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4	1.2	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.4	0.8	GO:0035262	gonad morphogenesis(GO:0035262)
0.4	1.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.4	0.4	GO:0097168	condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.4	0.8	GO:0007403	glial cell fate determination(GO:0007403)
0.4	1.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.4	3.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.4	1.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4	1.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.4	1.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.4	1.9	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.4	1.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.4	1.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.4	0.7	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.4	1.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4	1.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4	8.0	GO:0035640	exploration behavior(GO:0035640)
0.4	0.7	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.4	1.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4	1.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.4	1.4	GO:0050975	sensory perception of touch(GO:0050975)
0.4	1.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.4	1.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.4	1.8	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.4	1.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	1.8	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.4	0.7	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.3	1.0	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3	0.3	GO:2000739	regulation of mesenchymal stem cell differentiation(GO:2000739)
0.3	1.0	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3	0.7	GO:0002339	B cell selection(GO:0002339)
0.3	1.3	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.3	1.7	GO:0042693	muscle cell fate commitment(GO:0042693)
0.3	1.3	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.3	0.3	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.3	2.7	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.3	2.7	GO:0042989	sequestering of actin monomers(GO:0042989)
0.3	0.3	GO:0060601	lateral sprouting from an epithelium(GO:0060601)
0.3	0.7	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3	1.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.3	0.3	GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.3	0.6	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.3	0.3	GO:0021586	pons maturation(GO:0021586)
0.3	2.4	GO:0003417	growth plate cartilage development(GO:0003417)
0.3	5.4	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.3	0.9	GO:0097503	sialylation(GO:0097503)
0.3	1.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3	1.8	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.3	0.9	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.3	5.1	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.3	1.8	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.3	1.8	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.3	1.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.3	2.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.3	0.9	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.3	2.3	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3	1.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.3	1.7	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.3	0.6	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.3	1.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.3	2.0	GO:0006108	malate metabolic process(GO:0006108)
0.3	0.3	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.3	0.8	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	1.4	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.3	0.8	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.3	0.3	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.3	0.6	GO:0007412	axon target recognition(GO:0007412)
0.3	0.8	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.3	1.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3	1.4	GO:1903975	regulation of glial cell migration(GO:1903975)
0.3	0.5	GO:0001757	somite specification(GO:0001757)
0.3	12.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.3	0.3	GO:0072106	regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.3	1.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.3	0.5	GO:0030421	defecation(GO:0030421)
0.3	0.8	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.3	0.8	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.3	0.5	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.3	0.5	GO:0072174	metanephric tubule formation(GO:0072174)
0.3	2.1	GO:0060581	ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.3	0.3	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.3	1.0	GO:0002692	negative regulation of cellular extravasation(GO:0002692)
0.3	0.8	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.3	1.5	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3	0.8	GO:0048840	otolith development(GO:0048840)
0.3	0.3	GO:0046684	response to pyrethroid(GO:0046684)
0.3	3.8	GO:0001964	startle response(GO:0001964)
0.3	0.8	GO:0007413	axonal fasciculation(GO:0007413)
0.3	1.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.3	0.8	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	1.0	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.3	1.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.3	1.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	1.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	0.7	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2	1.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.2	0.7	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.2	3.2	GO:0003334	keratinocyte development(GO:0003334)
0.2	0.7	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.2	0.7	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.2	1.7	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.2	0.7	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.2	1.7	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.2	0.7	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2	1.6	GO:0071420	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.2	0.5	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.2	0.5	GO:1900238	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.2	0.7	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	0.5	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.2	0.7	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2	0.7	GO:0032808	lacrimal gland development(GO:0032808)
0.2	0.9	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2	2.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2	1.1	GO:0072044	collecting duct development(GO:0072044)
0.2	0.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.2	0.2	GO:0060486	Clara cell differentiation(GO:0060486)
0.2	0.7	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.2	2.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.2	0.6	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.2	0.4	GO:0061055	myotome development(GO:0061055)
0.2	1.7	GO:1902855	regulation of nonmotile primary cilium assembly(GO:1902855)
0.2	0.4	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2	3.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.2	0.8	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.2	0.8	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.2	0.6	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.2	0.4	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2	1.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.2	1.9	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.2	0.6	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2	0.4	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2	0.6	GO:0034447	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) very-low-density lipoprotein particle clearance(GO:0034447)
0.2	1.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.2	0.2	GO:0072497	mesenchymal stem cell differentiation(GO:0072497)
0.2	0.4	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.2	0.6	GO:0001806	type IV hypersensitivity(GO:0001806)
0.2	1.2	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2	2.0	GO:0002176	male germ cell proliferation(GO:0002176)
0.2	1.8	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.2	1.4	GO:0008063	Toll signaling pathway(GO:0008063)
0.2	1.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.2	0.6	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2	0.2	GO:0014029	neural crest formation(GO:0014029)
0.2	0.6	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	0.4	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.2	3.1	GO:2001222	regulation of neuron migration(GO:2001222)
0.2	1.0	GO:0002317	plasma cell differentiation(GO:0002317)
0.2	2.1	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.2	0.2	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.2	0.8	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.2	0.6	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2	0.8	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	0.4	GO:0051665	membrane raft localization(GO:0051665)
0.2	0.6	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2	0.7	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.2	0.9	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.2	0.4	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698)
0.2	0.4	GO:0003344	pericardium morphogenesis(GO:0003344)
0.2	0.4	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.2	0.7	GO:1904659	glucose transmembrane transport(GO:1904659)
0.2	0.4	GO:0021559	trigeminal nerve development(GO:0021559)
0.2	2.1	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2	0.2	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.2	0.9	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.2	0.4	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.7	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2	0.2	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.2	0.3	GO:0003358	noradrenergic neuron development(GO:0003358)
0.2	0.7	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.2	0.5	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.2	0.5	GO:0060005	vestibular reflex(GO:0060005)
0.2	0.5	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	0.9	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	0.5	GO:0070889	platelet alpha granule organization(GO:0070889)
0.2	0.2	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.2	0.7	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	1.2	GO:0006105	succinate metabolic process(GO:0006105)
0.2	0.2	GO:1903012	positive regulation of bone development(GO:1903012)
0.2	0.5	GO:0031033	myosin filament organization(GO:0031033)
0.2	1.7	GO:0036119	response to platelet-derived growth factor(GO:0036119)
0.2	0.3	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.2	0.6	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.2	0.2	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.2	0.3	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.2	0.6	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2	1.8	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.2	0.6	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.2	0.2	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.2	0.5	GO:0010996	response to auditory stimulus(GO:0010996)
0.2	0.5	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.2	0.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.2	1.3	GO:0002329	pre-B cell differentiation(GO:0002329)
0.2	0.8	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2	0.2	GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.2	0.6	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.2	0.3	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2	0.5	GO:0006667	sphinganine metabolic process(GO:0006667)
0.2	0.5	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.5	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	0.3	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.2	0.6	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.2	0.6	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.2	0.6	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.2	0.2	GO:0015755	fructose transport(GO:0015755)
0.2	1.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.2	0.5	GO:2000412	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.1	0.4	GO:0002930	trabecular meshwork development(GO:0002930)
0.1	0.1	GO:1903276	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.1	0.4	GO:0099622	cardiac muscle cell membrane repolarization(GO:0099622) regulation of cardiac muscle cell membrane repolarization(GO:0099623)
0.1	0.6	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.4	GO:0006551	leucine metabolic process(GO:0006551)
0.1	0.4	GO:0008038	neuron recognition(GO:0008038)
0.1	0.1	GO:0003139	secondary heart field specification(GO:0003139)
0.1	0.7	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.7	GO:0015884	folic acid transport(GO:0015884)
0.1	1.1	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.4	GO:0090427	activation of meiosis(GO:0090427)
0.1	0.7	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	0.1	GO:0042640	anagen(GO:0042640)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	0.4	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.4	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.7	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
0.1	0.8	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.6	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.3	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.4	GO:0035810	positive regulation of urine volume(GO:0035810)
0.1	0.1	GO:0072141	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	0.1	GO:0048382	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) mesendoderm development(GO:0048382)
0.1	1.4	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	0.3	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1	0.4	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.6	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	0.5	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.9	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.5	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	0.6	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.1	0.5	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	1.3	GO:0015858	nucleoside transport(GO:0015858)
0.1	0.2	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.4	GO:0042637	catagen(GO:0042637)
0.1	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.2	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.1	0.3	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.1	0.7	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	1.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	3.4	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	0.5	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1	0.6	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.1	1.6	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1	0.5	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	2.4	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.6	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.1	0.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.3	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	1.3	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	1.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.6	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.2	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.7	GO:1901678	iron coordination entity transport(GO:1901678)
0.1	0.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	4.5	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.1	0.3	GO:0046075	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1	0.4	GO:1903421	regulation of synaptic vesicle recycling(GO:1903421)
0.1	0.3	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	0.7	GO:2001258	negative regulation of cation channel activity(GO:2001258)
0.1	0.4	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.1	0.2	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.2	GO:0048069	eye pigmentation(GO:0048069)
0.1	0.6	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.1	GO:0060459	left lung development(GO:0060459)
0.1	1.2	GO:0035418	protein localization to synapse(GO:0035418)
0.1	0.6	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.2	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.3	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.1	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.5	GO:0097062	dendritic spine maintenance(GO:0097062)
0.1	0.2	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	0.2	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1	0.6	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	0.9	GO:0070269	pyroptosis(GO:0070269)
0.1	0.3	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.1	1.3	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.5	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.1	0.4	GO:0031650	regulation of heat generation(GO:0031650)
0.1	0.6	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.1	0.1	GO:0061738	late endosomal microautophagy(GO:0061738)
0.1	0.3	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.1	0.2	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.1	0.5	GO:0035428	hexose transmembrane transport(GO:0035428)
0.1	0.2	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.1	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.1	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.1	0.4	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.1	0.2	GO:0070268	cornification(GO:0070268)
0.1	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.3	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.5	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.1	0.7	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.1	0.3	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	0.3	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.2	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1	0.3	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.1	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.1	GO:0021983	pituitary gland development(GO:0021983)
0.1	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.1	0.6	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	0.9	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1	0.1	GO:0014894	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	0.1	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.6	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.9	GO:0030901	midbrain development(GO:0030901)
0.1	0.2	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1	0.2	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	0.2	GO:0021554	optic nerve development(GO:0021554)
0.1	0.2	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.2	GO:0034030	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.4	GO:0001710	mesodermal cell fate commitment(GO:0001710)
0.1	0.4	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.1	0.3	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.1	0.2	GO:0035106	operant conditioning(GO:0035106)
0.1	0.2	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.2	GO:0071625	vocalization behavior(GO:0071625)
0.1	0.8	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	1.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.5	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.1	0.2	GO:0033504	floor plate development(GO:0033504)
0.1	0.1	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.2	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	1.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.2	GO:0014841	skeletal muscle satellite cell proliferation(GO:0014841)
0.1	0.3	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.1	0.2	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.1	0.6	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.4	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.1	0.9	GO:1900003	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1	0.4	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.4	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	1.4	GO:0006101	citrate metabolic process(GO:0006101)
0.1	0.2	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	0.3	GO:0023021	termination of signal transduction(GO:0023021)
0.1	0.1	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1	0.2	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.1	0.4	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.1	GO:0035826	rubidium ion transport(GO:0035826)
0.1	0.3	GO:0060353	regulation of cell adhesion molecule production(GO:0060353)
0.1	0.2	GO:0060973	cell migration involved in heart development(GO:0060973)
0.1	0.1	GO:0030916	otic vesicle formation(GO:0030916)
0.1	0.2	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.1	GO:0032275	luteinizing hormone secretion(GO:0032275)
0.1	1.0	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.2	GO:0042473	outer ear morphogenesis(GO:0042473)
0.1	0.1	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.1	0.5	GO:0030318	melanocyte differentiation(GO:0030318)
0.1	1.2	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.6	GO:0061377	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.1	0.1	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.1	0.3	GO:0021511	spinal cord patterning(GO:0021511)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.3	GO:0035989	tendon development(GO:0035989)
0.1	0.2	GO:0060004	reflex(GO:0060004)
0.1	0.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.1	GO:0003176	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.1	0.2	GO:1990928	response to amino acid starvation(GO:1990928)
0.1	0.8	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.1	0.1	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.1	3.4	GO:0097485	neuron projection guidance(GO:0097485)
0.1	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.1	0.1	GO:0061038	uterus morphogenesis(GO:0061038)
0.1	0.3	GO:0021854	hypothalamus development(GO:0021854)
0.1	1.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1	0.1	GO:0008212	mineralocorticoid metabolic process(GO:0008212)
0.1	0.5	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.1	0.2	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1	0.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.4	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1	0.2	GO:0032026	response to magnesium ion(GO:0032026)
0.1	0.5	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
0.1	0.2	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.1	0.4	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1	0.3	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.1	0.2	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.2	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	0.1	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.1	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	0.1	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.1	0.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	1.7	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1	0.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	0.4	GO:0035994	response to muscle stretch(GO:0035994)
0.1	0.1	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.1	GO:0000101	sulfur amino acid transport(GO:0000101)
0.1	0.1	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.1	0.1	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0	0.2	GO:0060179	male mating behavior(GO:0060179)
0.0	0.0	GO:2001279	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0	0.3	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.0	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.5	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:1902172	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0	0.1	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.1	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.2	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.3	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	1.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	1.2	GO:0031424	keratinization(GO:0031424)
0.0	0.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.0	GO:0002730	regulation of dendritic cell cytokine production(GO:0002730)
0.0	0.0	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.1	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.0	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.1	GO:0002839	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.2	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.0	GO:0060379	cardiac muscle cell myoblast differentiation(GO:0060379)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.3	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.0	0.3	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0060746	parental behavior(GO:0060746)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.0	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.0	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0	0.2	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.2	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0035878	nail development(GO:0035878)
0.0	0.3	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0038031	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.0	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.1	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.5	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.0	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.0	0.2	GO:0090197	positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.0	0.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.2	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	1.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.1	GO:0008355	olfactory learning(GO:0008355)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.2	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.8	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.3	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.0	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0	1.1	GO:0007612	learning(GO:0007612)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.3	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.4	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.0	GO:2000615	regulation of histone H3-K9 acetylation(GO:2000615)
0.0	0.0	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0048021	regulation of melanin biosynthetic process(GO:0048021) negative regulation of melanin biosynthetic process(GO:0048022) regulation of secondary metabolite biosynthetic process(GO:1900376) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.0	GO:0097278	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.0	GO:2000018	regulation of male gonad development(GO:2000018)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0009139	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.0	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0	0.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.0	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.2	GO:0051532	regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.0	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.0	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.0	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.0	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.0	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.2	GO:0035315	hair cell differentiation(GO:0035315)
0.0	0.0	GO:0060022	hard palate development(GO:0060022)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	9.6	GO:0005914	spot adherens junction(GO:0005914)
1.8	38.3	GO:0030057	desmosome(GO:0030057)
1.2	11.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.9	2.6	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.8	0.8	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.7	8.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7	2.6	GO:0030478	actin cap(GO:0030478)
0.7	2.6	GO:0044308	axonal spine(GO:0044308)
0.6	1.9	GO:0072534	perineuronal net(GO:0072534)
0.6	1.9	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.6	4.7	GO:0001520	outer dense fiber(GO:0001520)
0.6	2.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.6	5.6	GO:0035253	ciliary rootlet(GO:0035253)
0.5	3.8	GO:0030008	TRAPP complex(GO:0030008)
0.5	4.9	GO:0000137	Golgi cis cisterna(GO:0000137)
0.5	5.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.5	3.5	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5	3.9	GO:0016342	catenin complex(GO:0016342)
0.5	2.3	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.5	2.7	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.5	2.7	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.4	3.6	GO:0042788	polysomal ribosome(GO:0042788)
0.4	1.8	GO:0005593	FACIT collagen trimer(GO:0005593)
0.4	1.3	GO:0033010	paranodal junction(GO:0033010)
0.4	1.3	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.4	1.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.4	3.2	GO:0043083	synaptic cleft(GO:0043083)
0.4	1.1	GO:0005899	insulin receptor complex(GO:0005899)
0.4	1.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4	9.8	GO:0048786	presynaptic active zone(GO:0048786)
0.4	1.1	GO:0032280	symmetric synapse(GO:0032280)
0.4	1.4	GO:1990716	axonemal central apparatus(GO:1990716)
0.3	3.1	GO:0036156	inner dynein arm(GO:0036156)
0.3	1.7	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.3	5.4	GO:0005614	interstitial matrix(GO:0005614)
0.3	1.7	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	2.0	GO:1990075	periciliary membrane compartment(GO:1990075)
0.3	0.3	GO:1990812	growth cone filopodium(GO:1990812)
0.3	0.9	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.3	0.9	GO:0043194	axon initial segment(GO:0043194)
0.3	1.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3	1.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.3	2.3	GO:0071437	invadopodium(GO:0071437)
0.3	1.7	GO:0030314	junctional membrane complex(GO:0030314)
0.3	1.3	GO:0070531	BRCA1-A complex(GO:0070531)
0.3	1.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.3	2.4	GO:0097449	astrocyte projection(GO:0097449)
0.3	6.6	GO:0044295	axonal growth cone(GO:0044295)
0.3	2.9	GO:0030673	axolemma(GO:0030673)
0.3	3.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.3	8.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.3	1.3	GO:0005915	zonula adherens(GO:0005915)
0.2	0.7	GO:0055087	Ski complex(GO:0055087)
0.2	5.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.2	1.0	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2	0.7	GO:0033268	node of Ranvier(GO:0033268)
0.2	1.6	GO:0044327	dendritic spine head(GO:0044327)
0.2	2.6	GO:0032433	filopodium tip(GO:0032433)
0.2	3.9	GO:0042734	presynaptic membrane(GO:0042734)
0.2	1.3	GO:0031983	vesicle lumen(GO:0031983)
0.2	0.6	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.2	2.3	GO:0001527	microfibril(GO:0001527)
0.2	0.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	3.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	0.6	GO:0048179	activin receptor complex(GO:0048179)
0.2	33.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.2	0.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	0.6	GO:0005608	laminin-3 complex(GO:0005608)
0.2	0.6	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.2	0.7	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	0.5	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	0.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	1.2	GO:0033263	CORVET complex(GO:0033263)
0.2	0.9	GO:0045098	type III intermediate filament(GO:0045098)
0.2	0.7	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	1.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.2	9.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.2	1.4	GO:0005859	muscle myosin complex(GO:0005859)
0.2	0.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.2	1.5	GO:0000813	ESCRT I complex(GO:0000813)
0.2	1.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	1.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.2	1.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	4.3	GO:0031941	filamentous actin(GO:0031941)
0.1	3.1	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	19.6	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	1.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.8	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	1.0	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	2.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.3	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.4	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.1	1.2	GO:0097542	ciliary tip(GO:0097542)
0.1	0.5	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.3	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	0.5	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.2	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	0.4	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	1.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.6	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.5	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	1.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	1.2	GO:0042555	MCM complex(GO:0042555)
0.1	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	3.8	GO:0030175	filopodium(GO:0030175)
0.1	0.7	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	0.2	GO:0097441	basilar dendrite(GO:0097441)
0.1	0.4	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.1	GO:0044393	microspike(GO:0044393)
0.1	0.6	GO:0000798	nuclear cohesin complex(GO:0000798)
0.1	0.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.1	0.9	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.1	1.1	GO:0097546	ciliary base(GO:0097546)
0.1	6.9	GO:0043204	perikaryon(GO:0043204)
0.1	0.3	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.4	GO:0071547	piP-body(GO:0071547)
0.1	0.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	2.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.4	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.1	0.2	GO:0000802	transverse filament(GO:0000802)
0.1	1.1	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.5	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.5	GO:0032589	neuron projection membrane(GO:0032589)
0.1	0.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	3.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.1	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.3	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	0.2	GO:0071942	XPC complex(GO:0071942)
0.1	0.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.0	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.7	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0016460	myosin II complex(GO:0016460)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.0	GO:0036396	MIS complex(GO:0036396)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	33.8	GO:0070324	thyroid hormone binding(GO:0070324)
1.3	2.6	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
1.3	6.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
1.3	3.8	GO:0030620	U2 snRNA binding(GO:0030620)
1.2	3.6	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.2	3.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
1.2	5.8	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.1	3.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
1.1	1.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
1.0	3.0	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.9	3.7	GO:0004065	arylsulfatase activity(GO:0004065)
0.9	4.6	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8	3.3	GO:1904288	BAT3 complex binding(GO:1904288)
0.8	2.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8	2.4	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.8	3.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.8	2.3	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.7	3.0	GO:0005042	netrin receptor activity(GO:0005042)
0.7	1.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.7	6.4	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.7	4.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.7	2.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.7	8.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.7	3.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.7	0.7	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.7	3.4	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.7	9.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.7	2.6	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.6	1.9	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.6	2.6	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.6	15.5	GO:0045499	chemorepellent activity(GO:0045499)
0.6	2.5	GO:0033142	progesterone receptor binding(GO:0033142)
0.6	1.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.6	1.8	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.6	3.4	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.6	1.7	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.5	4.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5	3.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.5	1.6	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.5	1.6	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.5	2.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.5	1.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.5	2.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5	4.4	GO:0004017	adenylate kinase activity(GO:0004017)
0.5	2.4	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5	2.4	GO:0070883	pre-miRNA binding(GO:0070883)
0.5	5.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.5	2.7	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.4	2.7	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.4	1.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.4	1.3	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.4	0.8	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4	1.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.4	1.7	GO:0038064	collagen receptor activity(GO:0038064)
0.4	2.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4	1.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.4	1.6	GO:0004594	pantothenate kinase activity(GO:0004594)
0.4	2.7	GO:0003680	AT DNA binding(GO:0003680)
0.4	1.5	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.4	1.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.4	1.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.4	11.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.4	1.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3	1.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3	1.0	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.3	1.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.3	0.7	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.3	1.0	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3	1.0	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3	1.3	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3	1.0	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.3	1.0	GO:0051380	norepinephrine binding(GO:0051380)
0.3	2.8	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3	1.5	GO:0004111	creatine kinase activity(GO:0004111)
0.3	1.5	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3	0.9	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3	1.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3	0.9	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.3	1.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3	1.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	0.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.3	5.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	6.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3	0.9	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	2.6	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.3	0.6	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3	1.1	GO:0015368	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.3	0.5	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.3	0.5	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.3	1.9	GO:0031628	opioid receptor binding(GO:0031628)
0.3	1.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.3	10.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.3	0.8	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.3	5.3	GO:0003785	actin monomer binding(GO:0003785)
0.3	2.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.3	1.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.3	1.0	GO:0070052	collagen V binding(GO:0070052)
0.3	5.0	GO:0043813	phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) transmembrane receptor protein phosphatase activity(GO:0019198) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.2	1.5	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	1.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2	0.7	GO:0005502	11-cis retinal binding(GO:0005502)
0.2	1.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	0.7	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.2	0.7	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.2	1.5	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.2	1.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.2	0.8	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.2	1.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	3.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.2	0.8	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2	0.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	1.0	GO:0004565	beta-galactosidase activity(GO:0004565)
0.2	1.9	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.2	1.0	GO:1990254	keratin filament binding(GO:1990254)
0.2	0.6	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2	0.8	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.2	1.0	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.4	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.2	0.4	GO:0034618	arginine binding(GO:0034618)
0.2	1.0	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2	0.9	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.2	0.6	GO:0034056	estrogen response element binding(GO:0034056)
0.2	0.9	GO:0016936	galactoside binding(GO:0016936)
0.2	0.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	0.5	GO:0018594	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.2	2.3	GO:0031005	filamin binding(GO:0031005)
0.2	1.6	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.2	1.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.2	4.9	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.2	1.9	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2	0.5	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	0.7	GO:0004969	histamine receptor activity(GO:0004969)
0.2	3.4	GO:0071837	HMG box domain binding(GO:0071837)
0.2	1.0	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	0.3	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.2	0.8	GO:0048406	nerve growth factor binding(GO:0048406)
0.2	0.2	GO:0008579	JUN kinase phosphatase activity(GO:0008579)
0.2	1.6	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	5.6	GO:0019894	kinesin binding(GO:0019894)
0.2	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	1.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	7.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2	1.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	0.5	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2	1.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	1.7	GO:0005522	profilin binding(GO:0005522)
0.1	0.6	GO:0097001	ceramide binding(GO:0097001)
0.1	1.0	GO:0031432	titin binding(GO:0031432)
0.1	0.6	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	0.4	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1	0.4	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	0.7	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.1	1.9	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.1	0.4	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.7	GO:0008312	7S RNA binding(GO:0008312)
0.1	0.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.4	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	2.0	GO:0031402	sodium ion binding(GO:0031402)
0.1	0.4	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	0.7	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	2.2	GO:0005112	Notch binding(GO:0005112)
0.1	0.8	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	1.0	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	5.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.9	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	1.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.4	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	2.0	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.5	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.7	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.4	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	2.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.5	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	1.0	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.2	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.3	GO:0019862	IgA binding(GO:0019862)
0.1	0.6	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.6	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.6	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0032564	dATP binding(GO:0032564)
0.1	0.4	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.1	1.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.1	1.1	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.1	GO:0038100	nodal binding(GO:0038100)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	7.2	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.1	2.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.6	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	1.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.5	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.6	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1	2.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.5	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1	0.3	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1	0.4	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	1.6	GO:0001968	fibronectin binding(GO:0001968)
0.1	1.9	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	2.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	1.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.7	GO:0009881	photoreceptor activity(GO:0009881)
0.1	2.5	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	1.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	1.0	GO:0030553	cGMP binding(GO:0030553)
0.1	1.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.5	GO:0032052	bile acid binding(GO:0032052)
0.1	0.3	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.5	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	11.7	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.1	0.3	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	1.0	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	0.2	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.2	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1	1.0	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.9	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	1.1	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.1	0.4	GO:0034711	inhibin binding(GO:0034711)
0.1	0.3	GO:0070878	primary miRNA binding(GO:0070878)
0.1	0.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.1	GO:0001226	RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.1	1.6	GO:0035254	glutamate receptor binding(GO:0035254)
0.1	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.1	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	2.0	GO:0005109	frizzled binding(GO:0005109)
0.1	0.3	GO:0034584	piRNA binding(GO:0034584)
0.1	0.3	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.2	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.1	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.3	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.5	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	2.1	GO:0005080	protein kinase C binding(GO:0005080)
0.1	2.0	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.3	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.1	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.7	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.1	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1	0.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	1.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.3	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.4	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.4	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.4	GO:0070694	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.6	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.5	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.9	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0019187	beta-1,4-mannosyltransferase activity(GO:0019187)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity(GO:0004952)
0.0	2.3	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	5.3	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.4	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.0	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.0	GO:0018501	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.3	GO:0005267	potassium channel activity(GO:0005267)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.0	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	5.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	4.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	10.5	NABA COLLAGENS	Genes encoding collagen proteins
0.2	7.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	1.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	1.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	9.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	0.4	PID S1P S1P3 PATHWAY	S1P3 pathway
0.2	1.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	4.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	1.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	5.9	PID SHP2 PATHWAY	SHP2 signaling
0.1	4.0	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	2.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	1.2	PID ENDOTHELIN PATHWAY	Endothelins
0.1	17.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	1.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	1.0	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	0.9	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	0.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	0.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	0.7	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	2.9	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	11.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	3.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.4	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	33.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.4	30.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.9	13.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.7	9.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.5	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.5	5.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	15.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.4	13.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.4	7.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	2.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.3	5.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3	5.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.3	6.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.3	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	9.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	6.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.2	2.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	2.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	2.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	4.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	2.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	2.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	2.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	2.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2	2.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.2	1.5	REACTOME OPSINS	Genes involved in Opsins
0.2	0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.2	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2	0.5	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.2	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	1.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	1.9	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	5.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	1.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	3.5	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	2.9	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	1.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.9	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1	0.7	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.1	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.1	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	0.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors

Results for Pitx2_Otx2

Z-value: 1.79

Motif logo

Transcription factors associated with Pitx2_Otx2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Pitx2_Otx2 motif across conditions

Conditions sorted by the z-value of the Pitx2_Otx2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: