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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Sox1

Z-value: 1.36

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Transcription factors associated with Sox1

Gene Symbol	Gene ID	Gene Info
Sox1 Ensembl NCBI MGI UniProt	ENSMUSG00000096014.1	SRY (sex determining region Y)-box 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_12395459_12396076	Sox1	472	0.526097	-0.28	3.9e-02	Click!
chr8_12395099_12395287	Sox1	102	0.932546	-0.25	7.1e-02	Click!
chr8_12394849_12395069	Sox1	336	0.790116	-0.24	7.5e-02	Click!

Activity of the Sox1 motif across conditions

Conditions sorted by the z-value of the Sox1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_9472719_9472904	7.29	Gm50456	predicted gene, 50456	2691	0.29
chr7_81587259_81587432	4.95	Gm45698	predicted gene 45698	3549	0.13
chr2_24344923_24345074	4.95	Il1rn	interleukin 1 receptor antagonist	290	0.87
chr17_85928454_85928786	4.78	Gm30117	predicted gene, 30117	41	0.99
chr4_32570992_32571180	4.76	Bach2os	BTB and CNC homology 2, opposite strand	531	0.72
chr9_75980624_75980791	4.64	Gm25300	predicted gene, 25300	9680	0.15
chr8_105322928_105323084	4.55	Lrrc29	leucine rich repeat containing 29	3253	0.08
chr3_90258622_90258788	4.39	Crtc2	CREB regulated transcription coactivator 2	260	0.8
chr5_130034116_130034267	4.09	Crcp	calcitonin gene-related peptide-receptor component protein	4848	0.13
chr2_57252710_57252861	3.98	Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	8423	0.16
chr4_41353370_41353539	3.96	Ubap1	ubiquitin-associated protein 1	4406	0.14
chr7_135806753_135806904	3.94	Gm36431	predicted gene, 36431	37238	0.13
chr13_75733796_75734110	3.89	Gm48302	predicted gene, 48302	6674	0.14
chr6_86884820_86885083	3.80	Gm44152	predicted gene, 44152	11165	0.14
chr4_88526796_88526956	3.74	Ifnb1	interferon beta 1, fibroblast	4102	0.14
chr16_14155801_14155952	3.69	Marf1	meiosis regulator and mRNA stability 1	3391	0.17
chr13_112316899_112317050	3.67	Ankrd55	ankyrin repeat domain 55	1480	0.39
chr5_97834809_97835101	3.61	Antxr2	anthrax toxin receptor 2	161140	0.03
chr1_3515282_3515574	3.59	Gm37329	predicted gene, 37329	921	0.56
chr3_133007399_133007550	3.59	Gstcd	glutathione S-transferase, C-terminal domain containing	1797	0.29
chr15_77974560_77974737	3.51	Eif3d	eukaryotic translation initiation factor 3, subunit D	3835	0.18
chr3_27918341_27918492	3.49	Pld1	phospholipase D1	20279	0.19
chr17_31474444_31474595	3.42	Pde9a	phosphodiesterase 9A	3467	0.12
chr3_5396267_5396418	3.29	4930555M17Rik	RIKEN cDNA 4930555M17 gene	118991	0.06
chr2_31719315_31719479	3.27	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	29786	0.1
chr1_174600692_174600961	3.25	Fmn2	formin 2	8982	0.28
chr2_84798445_84798951	3.23	Ube2l6	ubiquitin-conjugating enzyme E2L 6	130	0.92
chr5_145454847_145454998	3.18	Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	14801	0.16
chr5_44239833_44239984	3.16	Tapt1	transmembrane anterior posterior transformation 1	13282	0.11
chr13_109481377_109481735	3.15	Pde4d	phosphodiesterase 4D, cAMP specific	39373	0.23
chr11_120648059_120648248	3.08	Myadml2	myeloid-associated differentiation marker-like 2	5	0.85
chr2_147944293_147944444	3.05	9030622O22Rik	RIKEN cDNA 9030622O22 gene	31817	0.18
chr2_165006923_165007125	3.04	Ncoa5	nuclear receptor coactivator 5	2361	0.22
chrX_165050100_165050251	3.04	Gm17604	predicted gene, 17604	45346	0.16
chr13_77548432_77549057	2.95	Gm9634	predicted gene 9634	5629	0.31
chr4_33471003_33471163	2.92	Gm11935	predicted gene 11935	18194	0.21
chr3_104632973_104633136	2.90	Gm43582	predicted gene 43582	1603	0.22
chr8_93234132_93234302	2.88	Ces1e	carboxylesterase 1E	4598	0.15
chr18_65225902_65226053	2.88	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	18093	0.14
chr5_90560713_90561116	2.84	Albfm1	albumin superfamily member 1	193	0.9
chr13_54073147_54073331	2.84	Sfxn1	sideroflexin 1	1370	0.43
chr2_126359408_126359559	2.80	Atp8b4	ATPase, class I, type 8B, member 4	132070	0.05
chr1_85838028_85838331	2.79	Cab39	calcium binding protein 39	4901	0.17
chr5_140118439_140118590	2.79	Mad1l1	MAD1 mitotic arrest deficient 1-like 1	3048	0.21
chr17_84146640_84146791	2.74	Gm19696	predicted gene, 19696	6874	0.17
chr10_57727708_57728009	2.71	Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	123	0.97
chr6_85908437_85908607	2.70	Tprkb	Tp53rk binding protein	3343	0.1
chr18_84199752_84199903	2.70	Gm50311	predicted gene, 50311	3097	0.31
chr12_32110648_32110840	2.62	5430401H09Rik	RIKEN cDNA 5430401H09 gene	12958	0.18
chr13_105139845_105140060	2.60	Nt5el	5' nucleotidase, ecto-like	57830	0.13
chr5_96951235_96951434	2.59	Gm43144	predicted gene 43144	11037	0.1
chr5_122288228_122288379	2.59	Pptc7	PTC7 protein phosphatase homolog	3938	0.14
chr9_50700969_50701175	2.59	Dixdc1	DIX domain containing 1	1635	0.27
chr11_116195856_116196007	2.59	Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	2798	0.13
chr8_22564005_22564156	2.57	Vdac3	voltage-dependent anion channel 3	22041	0.13
chr8_35567567_35567732	2.54	Mfhas1	malignant fibrous histiocytoma amplified sequence 1	20149	0.17
chr11_110101720_110101878	2.54	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a	5821	0.27
chr14_75138507_75138871	2.48	Gm15628	predicted gene 15628	1777	0.27
chr5_90568933_90569084	2.48	Albfm1	albumin superfamily member 1	7791	0.13
chr4_94562043_94562194	2.48	Caap1	caspase activity and apoptosis inhibitor 1	5322	0.16
chr3_153611438_153611589	2.48	Gm22206	predicted gene, 22206	97398	0.06
chr2_38621804_38622039	2.47	Gm13586	predicted gene 13586	880	0.48
chr17_25127091_25127504	2.45	Clcn7	chloride channel, voltage-sensitive 7	6094	0.1
chr12_102743871_102744241	2.42	Tmem251	transmembrane protein 251	294	0.53
chr6_29500949_29501100	2.42	Kcp	kielin/chordin-like protein	1800	0.2
chr11_3566126_3566403	2.41	Smtn	smoothelin	25652	0.09
chr4_110227799_110227964	2.35	Elavl4	ELAV like RNA binding protein 4	4733	0.34
chr10_100132423_100132589	2.32	Gm22918	predicted gene, 22918	6995	0.15
chr10_71338615_71338766	2.28	Cisd1	CDGSH iron sulfur domain 1	6264	0.14
chr11_3164450_3165050	2.26	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	153	0.93
chr13_102022899_102023050	2.25	Gm38133	predicted gene, 38133	93061	0.08
chr4_132530023_132530322	2.25	Gm12999	predicted gene 12999	2515	0.14
chr5_146009208_146009359	2.24	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	315	0.84
chr6_122571342_122571500	2.22	Gm16556	predicted gene 16556	572	0.59
chr8_25193106_25193301	2.21	Tacc1	transforming, acidic coiled-coil containing protein 1	7340	0.19
chr14_36316822_36316973	2.20	Gm48663	predicted gene, 48663	84856	0.1
chr1_168289252_168289426	2.18	Gm37524	predicted gene, 37524	48332	0.16
chr13_101861969_101862287	2.15	Gm47007	predicted gene, 47007	6637	0.22
chr17_28253317_28253479	2.14	Ppard	peroxisome proliferator activator receptor delta	18310	0.1
chr5_24069058_24069210	2.14	Gm18038	predicted gene, 18038	16110	0.13
chr12_117554619_117554857	2.08	Gm24741	predicted gene, 24741	19604	0.19
chr16_41242880_41243222	2.07	Gm47276	predicted gene, 47276	25274	0.22
chr7_79283245_79283518	2.05	Gm44639	predicted gene 44639	5614	0.14
chr7_142331383_142331552	2.05	Ifitm10	interferon induced transmembrane protein 10	6555	0.09
chr12_3288807_3288958	2.02	Rab10	RAB10, member RAS oncogene family	21087	0.14
chr7_132739924_132740091	2.01	Fam53b	family with sequence similarity 53, member B	36909	0.14
chr7_49145938_49146333	2.01	9130015G15Rik	RIKEN cDNA 9130015G15 gene	11859	0.2
chr5_140647773_140649317	1.98	Ttyh3	tweety family member 3	452	0.77
chr17_86313044_86313195	1.98	2010106C02Rik	RIKEN cDNA 2010106C02 gene	25941	0.24
chrX_101428817_101430172	1.97	Nono	non-POU-domain-containing, octamer binding protein	61	0.96
chr12_100475558_100475741	1.95	Ttc7b	tetratricopeptide repeat domain 7B	9351	0.16
chr2_104095422_104095586	1.95	Cd59a	CD59a antigen	297	0.84
chr18_8966820_8967020	1.92	Gm7523	predicted gene 7523	824	0.71
chr1_37026079_37026236	1.91	Vwa3b	von Willebrand factor A domain containing 3B	439	0.82
chr5_122027235_122027386	1.90	Gm3970	predicted gene 3970	1980	0.27
chr15_36820211_36820408	1.89	Gm25303	predicted gene, 25303	21538	0.13
chr11_114685374_114685525	1.89	Ttyh2	tweety family member 2	9933	0.15
chr15_62328370_62328915	1.87	Pvt1	Pvt1 oncogene	106039	0.07
chr16_18407921_18408164	1.87	Arvcf	armadillo repeat gene deleted in velocardiofacial syndrome	4546	0.11
chr19_32626526_32626677	1.87	Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	6596	0.24
chr1_23202952_23203142	1.86	Gm29506	predicted gene 29506	32626	0.13
chr19_45528067_45528218	1.86	Poll	polymerase (DNA directed), lambda	32389	0.13
chr11_103115898_103116281	1.84	Hexim1	hexamethylene bis-acetamide inducible 1	142	0.93
chr1_132368268_132368561	1.82	Tmcc2	transmembrane and coiled-coil domains 2	527	0.69
chr1_24613351_24614205	1.82	Gm28437	predicted gene 28437	193	0.69
chr10_41912747_41912929	1.81	Sesn1	sestrin 1	14465	0.21
chr2_167649430_167649581	1.80	Tmem189	transmembrane protein 189	4328	0.12
chrX_164145479_164145798	1.78	Ace2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	5160	0.19
chr4_103396023_103396174	1.74	Gm12718	predicted gene 12718	13577	0.2
chr3_19665152_19665357	1.73	BC002189	cDNA sequence BC002189	20717	0.13
chrX_104602569_104602751	1.72	Gm22430	predicted gene, 22430	14205	0.24
chr6_141522685_141522836	1.72	Slco1c1	solute carrier organic anion transporter family, member 1c1	1608	0.49
chrX_104603844_104604019	1.71	Gm22430	predicted gene, 22430	12934	0.24
chr9_45788631_45788801	1.70	Cep164	centrosomal protein 164	5550	0.14
chr4_49452293_49452444	1.69	Acnat1	acyl-coenzyme A amino acid N-acyltransferase 1	1231	0.37
chr15_81530599_81530871	1.69	Gm5218	predicted gene 5218	31190	0.1
chr8_111509409_111509600	1.67	Wdr59	WD repeat domain 59	12483	0.17
chr4_107109283_107109576	1.65	Cdcp2	CUB domain containing protein 2	11721	0.13
chr8_14890288_14890615	1.65	Cln8	CLN8 transmembrane ER and ERGIC protein	1092	0.51
chr16_38454123_38454296	1.64	Cd80	CD80 antigen	1352	0.24
chr3_60504817_60504968	1.64	Mbnl1	muscleblind like splicing factor 1	3614	0.29
chr1_193327858_193328009	1.61	Lamb3	laminin, beta 3	7238	0.13
chr10_80071527_80071891	1.61	Sbno2	strawberry notch 2	3691	0.11
chr6_81661085_81661448	1.60	Gm26264	predicted gene, 26264	22955	0.21
chr2_67881680_67881831	1.57	Gm37964	predicted gene, 37964	16841	0.24
chr14_65890162_65890336	1.57	Ccdc25	coiled-coil domain containing 25	52889	0.1
chr16_24517130_24517281	1.55	Morf4l1-ps1	mortality factor 4 like 1, pseudogene 1	12189	0.25
chr19_53360248_53360544	1.54	Mxi1	MAX interactor 1, dimerization protein	9627	0.13
chr10_3281099_3281250	1.53	H60c	histocompatibility 60c	13403	0.18
chr19_58050434_58050717	1.52	Mir5623	microRNA 5623	592	0.82
chr1_173354873_173355029	1.52	Aim2	absent in melanoma 2	4072	0.18
chr13_44839668_44840451	1.51	Jarid2	jumonji, AT rich interactive domain 2	632	0.7
chr9_120118309_120118460	1.50	Slc25a38	solute carrier family 25, member 38	3395	0.1
chr10_116884549_116884846	1.49	Myrfl	myelin regulatory factor-like	12222	0.16
chr11_74831594_74833056	1.47	Mnt	max binding protein	1405	0.31
chr6_21787269_21787608	1.46	Tspan12	tetraspanin 12	64390	0.11
chr9_65294042_65294965	1.44	Clpx	caseinolytic mitochondrial matrix peptidase chaperone subunit	171	0.9
chr13_59521707_59521858	1.43	Agtpbp1	ATP/GTP binding protein 1	7628	0.17
chr12_105757874_105758401	1.43	Ak7	adenylate kinase 7	12862	0.17
chr1_39425558_39425731	1.42	Gm37265	predicted gene, 37265	5712	0.18
chr8_117359845_117360139	1.42	Cmip	c-Maf inducing protein	10822	0.25
chr15_12368166_12368317	1.42	Pdzd2	PDZ domain containing 2	44139	0.12
chr3_142434903_142435070	1.42	Pdlim5	PDZ and LIM domain 5	39290	0.15
chr4_47310823_47311025	1.41	Col15a1	collagen, type XV, alpha 1	7202	0.23
chr15_56005470_56005643	1.40	Gm49211	predicted gene, 49211	1512	0.37
chr11_31897007_31897284	1.39	Cpeb4	cytoplasmic polyadenylation element binding protein 4	23870	0.18
chr1_53850972_53851170	1.36	Mir7681	microRNA 7681	1647	0.35
chr14_55577823_55578992	1.36	Psme1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	2	0.91
chr14_31006914_31007106	1.35	Glt8d1	glycosyltransferase 8 domain containing 1	377	0.7
chr1_86498055_86498824	1.35	Rpl30-ps6	ribosomal protein L30, pseudogene 6	24780	0.11
chr11_12205532_12205894	1.33	Gm12001	predicted gene 12001	77715	0.1
chr13_35016430_35016581	1.33	Eci2	enoyl-Coenzyme A delta isomerase 2	10589	0.12
chr8_126615714_126616182	1.33	Irf2bp2	interferon regulatory factor 2 binding protein 2	21962	0.21
chr13_84805285_84805751	1.30	Gm26913	predicted gene, 26913	114577	0.06
chr12_51376987_51377614	1.29	Scfd1	Sec1 family domain containing 1	210	0.95
chr10_108172954_108173148	1.24	Ppp1r12a	protein phosphatase 1, regulatory subunit 12A	10651	0.24
chr3_57428795_57428983	1.24	Tm4sf4	transmembrane 4 superfamily member 4	3575	0.28
chr5_123933674_123933853	1.24	Ccdc62	coiled-coil domain containing 62	3074	0.15
chr18_12234848_12235027	1.24	Npc1	NPC intracellular cholesterol transporter 1	1389	0.37
chr17_24721071_24721245	1.21	Rps2	ribosomal protein S2	291	0.45
chr6_91121562_91121713	1.21	Gm44278	predicted gene, 44278	702	0.61
chrX_41319968_41320254	1.21	Gm14577	predicted gene 14577	52148	0.15
chr5_76828559_76829372	1.20	C530008M17Rik	RIKEN cDNA C530008M17 gene	11634	0.19
chr2_93008659_93008810	1.20	Prdm11	PR domain containing 11	5176	0.22
chr14_31428304_31428502	1.20	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	7662	0.15
chr6_13921201_13921391	1.18	Gm44412	predicted gene, 44412	7848	0.21
chr9_44320553_44320966	1.18	C2cd2l	C2 calcium-dependent domain containing 2-like	474	0.52
chrX_136171736_136172077	1.18	Tceal8	transcription elongation factor A (SII)-like 8	295	0.83
chr4_133874044_133874208	1.18	Rps6ka1	ribosomal protein S6 kinase polypeptide 1	605	0.57
chr7_89140693_89141295	1.17	Tmem135	transmembrane protein 135	4503	0.3
chr15_5235569_5235899	1.15	Ptger4	prostaglandin E receptor 4 (subtype EP4)	6976	0.15
chr6_103810041_103810781	1.14	Gm25656	predicted gene, 25656	22167	0.25
chr11_14350536_14350733	1.14	Gm12006	predicted gene 12006	136979	0.05
chr6_42265421_42265665	1.13	Casp2	caspase 2	423	0.71
chr10_53888423_53888607	1.13	Gm47915	predicted gene, 47915	84986	0.08
chr15_80256965_80257160	1.13	Atf4	activating transcription factor 4	1539	0.24
chr1_71586818_71586969	1.12	Fn1	fibronectin 1	4178	0.23
chr17_29499759_29499915	1.12	Pim1	proviral integration site 1	6430	0.11
chr10_122106000_122106151	1.12	Rxylt1	ribitol xylosyltransferase 1	8704	0.14
chr6_54720625_54720776	1.12	Gm44008	predicted gene, 44008	27054	0.15
chr18_47334258_47334452	1.12	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	1007	0.61
chr8_33733324_33733484	1.09	Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)	39	0.96
chr6_100233596_100233868	1.09	Rybp	RING1 and YY1 binding protein	601	0.72
chr6_116349806_116349968	1.09	Marchf8	membrane associated ring-CH-type finger 8	498	0.7
chr13_58067512_58068080	1.09	Klhl3	kelch-like 3	34632	0.13
chr14_51082610_51082856	1.09	Olfr750	olfactory receptor 750	8298	0.08
chr16_91869749_91869900	1.06	Itsn1	intersectin 1 (SH3 domain protein 1A)	7729	0.16
chr5_135698376_135698527	1.05	Gm16061	predicted gene 16061	568	0.61
chr8_81806886_81807095	1.05	Gm17169	predicted gene 17169	16082	0.2
chr8_46529662_46529955	1.05	Acsl1	acyl-CoA synthetase long-chain family member 1	1256	0.41
chr3_84262915_84263115	1.05	Trim2	tripartite motif-containing 2	3203	0.33
chr4_33343330_33343484	1.04	Rngtt	RNA guanylyltransferase and 5'-phosphatase	12393	0.19
chr5_87376122_87376273	1.04	Gm21049	predicted gene, 21049	3723	0.13
chr7_84688330_84688481	1.04	2610206C17Rik	RIKEN cDNA 2610206C17 gene	1235	0.36
chr8_122960440_122960605	1.03	Ankrd11	ankyrin repeat domain 11	14251	0.13
chr2_26644013_26644164	1.03	Snhg7os	small nucleolar RNA host gene 7, opposite strand	199	0.87
chr14_98749454_98749605	1.03	Gm27034	predicted gene, 27034	34716	0.21
chr9_57312619_57312770	1.03	Gm18996	predicted gene, 18996	16721	0.14
chr13_59641372_59641523	1.02	Naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	8722	0.12
chr5_24969237_24969541	1.02	1500035N22Rik	RIKEN cDNA 1500035N22 gene	16453	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.6	3.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.5	1.9	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.4	1.7	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.4	1.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.4	2.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3	0.9	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3	3.5	GO:0043970	histone H3-K9 acetylation(GO:0043970)
0.3	0.8	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.2	1.2	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2	1.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.2	0.6	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	0.8	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.2	0.9	GO:0006528	asparagine metabolic process(GO:0006528)
0.2	0.5	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.5	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.2	0.8	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	0.8	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2	0.3	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.2	0.8	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.2	1.2	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.6	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.4	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.7	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.6	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.4	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.8	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.1	0.5	GO:2000551	regulation of T-helper 2 cell cytokine production(GO:2000551)
0.1	1.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1	0.7	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.7	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.3	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1	0.4	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.3	GO:0019042	viral latency(GO:0019042)
0.1	0.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.8	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.3	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	0.3	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.7	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.2	GO:0097195	pilomotor reflex(GO:0097195)
0.1	0.3	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1	0.4	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.1	1.7	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.2	GO:0071314	cellular response to cocaine(GO:0071314)
0.1	0.3	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.6	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1	0.4	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.5	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.1	0.2	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.1	0.2	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1	0.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.5	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.3	GO:0035106	operant conditioning(GO:0035106)
0.1	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.1	0.5	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.3	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1	0.5	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.6	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	0.5	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.2	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.2	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.1	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	0.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.4	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.1	0.2	GO:0038202	TORC1 signaling(GO:0038202) regulation of TORC1 signaling(GO:1903432) positive regulation of TORC1 signaling(GO:1904263)
0.1	0.2	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.1	0.5	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.3	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	1.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.1	0.8	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.1	0.5	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.5	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.2	GO:0072602	interleukin-4 secretion(GO:0072602)
0.1	0.2	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	0.2	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1	0.2	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.1	0.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.2	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.2	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.4	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	0.4	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
0.1	0.3	GO:0006477	protein sulfation(GO:0006477)
0.1	0.9	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	0.3	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.1	0.3	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.1	0.2	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.2	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.3	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.2	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.2	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	1.0	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	1.3	GO:0006826	iron ion transport(GO:0006826)
0.0	0.3	GO:0032570	response to progesterone(GO:0032570)
0.0	0.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.3	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.6	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	2.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.0	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.1	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.2	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.0	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0071440	regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.3	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	1.1	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.1	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.4	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	1.2	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.2	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.3	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.3	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.4	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0	0.6	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.6	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.3	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0	0.2	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.2	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.2	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.6	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.3	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	2.6	GO:0006821	chloride transport(GO:0006821)
0.0	0.1	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.3	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.2	GO:1901660	calcium ion export(GO:1901660)
0.0	0.7	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.1	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.4	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.2	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0	0.0	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.2	GO:0007614	short-term memory(GO:0007614)
0.0	0.1	GO:0032345	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.4	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.0	GO:1901563	response to camptothecin(GO:1901563)
0.0	0.0	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.0	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.7	GO:1901998	toxin transport(GO:1901998)
0.0	0.1	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.5	GO:0052695	uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.0	0.0	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	1.1	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.1	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.6	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.5	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0	0.1	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.0	GO:0045918	regulation of cytolysis(GO:0042268) negative regulation of cytolysis(GO:0045918)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.3	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.2	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.9	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	0.1	GO:0006563	L-serine metabolic process(GO:0006563)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.2	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.3	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.3	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0	0.1	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.0	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.3	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.7	GO:0006094	gluconeogenesis(GO:0006094)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.2	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.1	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.2	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.6	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.0	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.3	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.2	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0	0.2	GO:0070828	heterochromatin organization(GO:0070828)
0.0	0.1	GO:0043312	neutrophil degranulation(GO:0043312)
0.0	0.0	GO:0060502	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.2	GO:0043486	histone exchange(GO:0043486)
0.0	0.3	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0046490	isopentenyl diphosphate metabolic process(GO:0046490)
0.0	0.0	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.0	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0	0.1	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.1	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.0	0.8	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.7	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.0	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:0001865	NK T cell differentiation(GO:0001865)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.1	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.1	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.2	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.3	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0033058	directional locomotion(GO:0033058)
0.0	0.5	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525)
0.0	0.3	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.0	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.0	0.0	GO:0051198	negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.0	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.0	GO:1904816	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.0	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.0	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.3	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.0	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0051450	myoblast proliferation(GO:0051450)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0	0.2	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.6	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.2	GO:0051180	vitamin transport(GO:0051180)
0.0	0.0	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.0	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.0	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.4	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.0	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.1	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.0	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0043489	RNA stabilization(GO:0043489)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.7	GO:0030218	erythrocyte differentiation(GO:0030218)
0.0	0.1	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0006677	glycosylceramide metabolic process(GO:0006677)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.9	GO:0042382	paraspeckles(GO:0042382)
0.2	0.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	1.3	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.8	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.8	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.7	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.3	GO:0097413	Lewy body(GO:0097413)
0.1	0.5	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	0.6	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.2	GO:0035838	growing cell tip(GO:0035838)
0.1	1.0	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.4	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.2	GO:0031417	NatC complex(GO:0031417)
0.1	0.3	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.2	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.1	1.4	GO:0022624	proteasome accessory complex(GO:0022624)
0.1	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.2	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	0.3	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.5	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.6	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	2.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.4	GO:0071439	clathrin complex(GO:0071439)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.4	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.4	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.9	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.1	GO:0097450	astrocyte end-foot(GO:0097450)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.4	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.6	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.8	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.3	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.8	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	6.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0001650	fibrillar center(GO:0001650)
0.0	0.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	2.2	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	1.4	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	0.1	GO:1990752	microtubule end(GO:1990752)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	2.8	GO:0005819	spindle(GO:0005819)
0.0	0.4	GO:0000786	nucleosome(GO:0000786)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	4.0	GO:0005813	centrosome(GO:0005813)
0.0	0.3	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	1.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.0	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.6	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.0	GO:0019866	organelle inner membrane(GO:0019866)
0.0	0.0	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.6	4.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.4	3.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	2.0	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.4	3.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3	1.2	GO:0009374	biotin binding(GO:0009374)
0.3	1.7	GO:0097322	7SK snRNA binding(GO:0097322)
0.2	0.7	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2	0.6	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2	1.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.2	0.6	GO:0016842	amidine-lyase activity(GO:0016842)
0.2	0.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.2	0.5	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2	0.2	GO:0030523	dihydrolipoamide S-acyltransferase activity(GO:0030523)
0.1	0.7	GO:0043559	insulin binding(GO:0043559)
0.1	0.4	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.6	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.4	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	1.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.6	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1	0.4	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.5	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.4	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.5	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	0.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.3	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.6	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	0.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.5	GO:0070728	leucine binding(GO:0070728)
0.1	0.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.9	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.9	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1	0.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.5	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.3	GO:0045340	mercury ion binding(GO:0045340)
0.1	1.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.7	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.3	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	0.3	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.1	0.3	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.1	0.2	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.2	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	0.3	GO:0019808	polyamine binding(GO:0019808)
0.1	1.4	GO:0001848	complement binding(GO:0001848)
0.1	0.4	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.3	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.1	0.5	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.1	0.4	GO:0015288	porin activity(GO:0015288)
0.1	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.6	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.1	0.2	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	1.2	GO:0032452	histone demethylase activity(GO:0032452)
0.1	1.8	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.4	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	0.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.1	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	1.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	1.5	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	1.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.2	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	1.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.4	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.0	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	1.0	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.5	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	1.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	1.7	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0018856	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.0	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.5	GO:0043531	ADP binding(GO:0043531)
0.0	0.0	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.0	GO:0051766	inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	1.7	GO:0043492	ATPase activity, coupled to movement of substances(GO:0043492)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.2	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.2	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.5	GO:0043908	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.5	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.4	GO:0019707	protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.0	GO:0032564	dATP binding(GO:0032564)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	1.3	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.5	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.0	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.5	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.3	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.6	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.1	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	1.6	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0043176	amine binding(GO:0043176)
0.0	0.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.0	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.0	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	2.0	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	4.5	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.7	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	0.7	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	1.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	0.6	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	2.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	1.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	1.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	1.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.0	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing

Results for Sox1

Z-value: 1.36

Motif logo

Transcription factors associated with Sox1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox1 motif across conditions

Conditions sorted by the z-value of the Sox1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: