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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Sox2

Z-value: 5.84

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Transcription factors associated with Sox2

Gene Symbol	Gene ID	Gene Info
Sox2 Ensembl NCBI MGI UniProt	ENSMUSG00000074637.4	SRY (sex determining region Y)-box 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_34649198_34650117	Sox2	748	0.503632	0.82	1.0e-14	Click!
chr3_34650209_34650435	Sox2	83	0.947031	0.82	2.5e-14	Click!
chr3_34650777_34651154	Sox2	560	0.624757	0.81	9.8e-14	Click!
chr3_34648225_34648376	Sox2	2105	0.189031	0.80	2.0e-13	Click!
chr3_34647874_34648037	Sox2	2450	0.168082	0.75	5.9e-11	Click!

Activity of the Sox2 motif across conditions

Conditions sorted by the z-value of the Sox2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_108433472_108434154	44.23	Gm22942	predicted gene, 22942	7517	0.09
chr6_89613728_89614091	40.85	Chchd6	coiled-coil-helix-coiled-coil-helix domain containing 6	18257	0.17
chr9_41697271_41698297	39.86	Gm48784	predicted gene, 48784	22730	0.14
chr10_106609605_106610022	37.36	4930532I03Rik	RIKEN cDNA 4930532I03 gene	7333	0.29
chr12_3236518_3237725	37.30	Rab10os	RAB10, member RAS oncogene family, opposite strand	510	0.74
chr14_66494473_66494955	35.86	Gm23899	predicted gene, 23899	96981	0.07
chr3_40070102_40070729	33.85	Gm42785	predicted gene 42785	246838	0.02
chr3_16819324_16819513	33.19	Gm26485	predicted gene, 26485	3894	0.38
chr3_127294086_127294512	33.16	Gm42970	predicted gene 42970	5374	0.15
chr1_172349913_172350109	32.97	Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	8801	0.11
chr15_66239660_66240017	32.89	Kcnq3	potassium voltage-gated channel, subfamily Q, member 3	46213	0.14
chr4_3082761_3083956	31.55	Vmn1r-ps2	vomeronasal 1 receptor, pseudogene 2	21234	0.18
chr3_19406344_19406802	31.36	Pde7a	phosphodiesterase 7A	95251	0.07
chr7_31149516_31150411	30.97	G630030J09Rik	RIKEN cDNA G630030J09 gene	435	0.6
chr13_54874229_54874840	30.90	Gm29431	predicted gene 29431	12936	0.13
chr8_65617940_65618821	30.67	Marchf1	membrane associated ring-CH-type finger 1	145	0.97
chr8_12947304_12948554	30.51	Mcf2l	mcf.2 transforming sequence-like	10	0.49
chr4_122998402_122999232	29.82	Mycl	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived	63	0.96
chr12_98573417_98573836	29.34	Kcnk10	potassium channel, subfamily K, member 10	1086	0.43
chr6_22794374_22794759	28.89	Gm25942	predicted gene, 25942	4748	0.17
chr14_68981312_68981674	28.60	Stc1	stanniocalcin 1	47745	0.13
chr16_90522093_90522383	28.59	Gm36001	predicted gene, 36001	28371	0.14
chr3_158062143_158062492	28.54	Lrrc40	leucine rich repeat containing 40	39	0.97
chr4_72233972_72234136	28.38	C630043F03Rik	RIKEN cDNA C630043F03 gene	32706	0.18
chr6_81660570_81661025	28.04	Gm26264	predicted gene, 26264	22486	0.22
chr17_88494469_88494803	27.89	Ppp1r21	protein phosphatase 1, regulatory subunit 21	35482	0.13
chr6_54554355_54554906	27.73	Scrn1	secernin 1	175	0.95
chr4_22301616_22301795	27.72	Gm11882	predicted gene 11882	25872	0.19
chr3_56955404_56955772	27.53	Gm22269	predicted gene, 22269	98562	0.08
chr14_54332194_54332698	27.34	Gm3945	predicted gene 3945	1771	0.19
chr10_29143551_29143727	27.30	Soga3	SOGA family member 3	200	0.8
chr10_29143863_29144732	26.80	Gm9996	predicted gene 9996	103	0.69
chr3_17796321_17796503	26.62	Mir124-2hg	Mir124-2 host gene (non-protein coding)	668	0.46
chr10_108133791_108134149	26.52	Gm47999	predicted gene, 47999	8462	0.25
chr15_91018414_91018934	26.50	Kif21a	kinesin family member 21A	31144	0.16
chr9_36821327_36821662	26.40	Fez1	fasciculation and elongation protein zeta 1 (zygin I)	370	0.82
chrX_143543266_143543620	26.00	Pak3	p21 (RAC1) activated kinase 3	24745	0.25
chr1_78190714_78190948	26.00	Pax3	paired box 3	6007	0.24
chr2_152048577_152049360	25.87	AA387200	expressed sequence AA387200	27840	0.11
chr16_16561093_16561486	25.85	Fgd4	FYVE, RhoGEF and PH domain containing 4	1070	0.53
chr9_13652356_13652901	25.73	Maml2	mastermind like transcriptional coactivator 2	9832	0.2
chr13_85773910_85774095	25.71	Gm47636	predicted gene, 47636	91331	0.09
chr15_73021189_73021788	25.66	Trappc9	trafficking protein particle complex 9	34322	0.18
chr3_66325480_66326023	25.23	Veph1	ventricular zone expressed PH domain-containing 1	28914	0.18
chr9_10269473_10269801	25.22	Gm24496	predicted gene, 24496	20950	0.22
chr2_93891393_93892295	24.95	Accsl	1-aminocyclopropane-1-carboxylate synthase (non-functional)-like	22687	0.14
chr6_63911299_63911450	24.93	Gm44075	predicted gene, 44075	127307	0.05
chr18_15544080_15544457	24.87	Aqp4	aquaporin 4	133286	0.05
chr3_128546488_128546865	24.77	Gm22293	predicted gene, 22293	6304	0.29
chr2_141074597_141074768	24.54	Macrod2	mono-ADP ribosylhydrolase 2	50620	0.15
chr11_32157683_32158170	24.52	Gm12109	predicted gene 12109	27079	0.12
chr5_33995599_33996957	24.25	Nat8l	N-acetyltransferase 8-like	294	0.82
chr2_53437450_53438022	23.94	Gm13501	predicted gene 13501	39249	0.2
chr16_33605736_33606716	23.92	Slc12a8	solute carrier family 12 (potassium/chloride transporters), member 8	9599	0.26
chr10_80300858_80301038	23.85	Apc2	APC regulator of WNT signaling pathway 2	86	0.91
chr2_152050523_152051049	23.76	AA387200	expressed sequence AA387200	26022	0.12
chr10_81364518_81366962	23.76	4930404N11Rik	RIKEN cDNA 4930404N11 gene	50	0.91
chr6_55920513_55920755	23.66	Itprid1	ITPR interacting domain containing 1	33809	0.21
chr14_16200666_16200873	23.54	Rpl31-ps3	ribosomal protein L31, pseudogene 3	24254	0.13
chrX_42361720_42361910	23.47	Gm14619	predicted gene 14619	14303	0.27
chr1_68047124_68047492	23.41	Gm15671	predicted gene 15671	23065	0.22
chr6_144313023_144313448	23.39	Sox5	SRY (sex determining region Y)-box 5	103667	0.08
chr10_108701445_108701650	23.35	Gm5136	predicted gene 5136	1387	0.53
chr4_3067329_3068553	23.34	Gm27878	predicted gene, 27878	16122	0.2
chr17_52601056_52601789	23.25	Gm27217	predicted gene 27217	1238	0.39
chr15_84417749_84418106	23.23	Shisal1	shisa like 1	25770	0.18
chr5_37245988_37246869	23.23	Crmp1	collapsin response mediator protein 1	583	0.76
chr3_108409761_108410771	23.14	Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2	5286	0.1
chr12_44403738_44404185	23.10	Gm48182	predicted gene, 48182	5829	0.21
chr8_123411336_123412017	23.06	Tubb3	tubulin, beta 3 class III	86	0.91
chr14_70659174_70659883	22.92	Npm2	nucleophosmin/nucleoplasmin 2	284	0.85
chr17_52602043_52602770	22.89	Gm27217	predicted gene 27217	254	0.55
chr3_17785697_17785901	22.79	Mir124-2hg	Mir124-2 host gene (non-protein coding)	4122	0.22
chr13_77892438_77892993	22.62	Pou5f2	POU domain class 5, transcription factor 2	132187	0.05
chr12_26802654_26802851	22.54	4933409F18Rik	RIKEN cDNA 4933409F18 gene	32107	0.23
chr14_66319706_66319909	22.53	Gm41183	predicted gene, 41183	21422	0.13
chr2_174917610_174917806	22.50	Gm14616	predicted gene 14616	61419	0.09
chr2_126015456_126015651	22.49	Fgf7	fibroblast growth factor 7	19105	0.23
chr12_80061788_80062584	22.46	Gm36660	predicted gene, 36660	19248	0.14
chr11_32087496_32088333	22.43	Gm12108	predicted gene 12108	13314	0.2
chr7_79497714_79498195	22.23	Mir9-3hg	Mir9-3 host gene	2072	0.16
chr2_17730264_17731671	22.22	Nebl	nebulette	76	0.98
chr19_33049205_33049364	22.15	Gm29863	predicted gene, 29863	20788	0.21
chr7_84409236_84410328	22.02	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	101	0.96
chr10_127078401_127078887	22.02	Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	263	0.78
chr4_107835452_107835981	22.01	Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	4731	0.12
chr5_52516049_52516436	22.01	Gm43685	predicted gene 43685	22589	0.13
chr13_57603438_57603669	22.01	Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	304034	0.01
chr18_49770746_49771045	22.00	Gm16283	predicted gene 16283	15101	0.18
chr7_97446538_97446946	21.82	Kctd14	potassium channel tetramerisation domain containing 14	4581	0.16
chr8_70119396_70119618	21.79	Ncan	neurocan	1366	0.21
chr8_90741015_90741332	21.75	Gm35850	predicted gene, 35850	398	0.82
chr7_64533404_64533751	21.72	Gm44721	predicted gene 44721	4152	0.22
chr5_124334425_124334781	21.70	2810006K23Rik	RIKEN cDNA 2810006K23 gene	6505	0.11
chr9_26518773_26519056	21.62	Gm30313	predicted gene, 30313	31039	0.22
chr13_83749857_83750036	21.58	C130071C03Rik	RIKEN cDNA C130071C03 gene	11083	0.12
chr4_97649219_97649597	21.37	E130114P18Rik	RIKEN cDNA E130114P18 gene	41328	0.18
chr3_13470653_13471071	21.35	Ralyl	RALY RNA binding protein-like	793	0.48
chr6_103558666_103559112	21.32	Gm44441	predicted gene, 44441	5467	0.16
chr4_22835787_22836371	21.28	Gm24078	predicted gene, 24078	88948	0.09
chr15_8781624_8782079	21.26	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	71087	0.11
chr18_33890616_33890776	21.24	Epb41l4a	erythrocyte membrane protein band 4.1 like 4a	943	0.66
chr15_58976304_58977052	21.17	Mtss1	MTSS I-BAR domain containing 1	4139	0.18
chr11_32383714_32384390	21.09	Sh3pxd2b	SH3 and PX domains 2B	36212	0.13
chr6_47239363_47240145	21.07	Cntnap2	contactin associated protein-like 2	4633	0.33
chr4_32923442_32923826	21.06	Ankrd6	ankyrin repeat domain 6	129	0.96
chr5_146592655_146592919	21.02	Gm34333	predicted gene, 34333	7315	0.13
chr9_52223852_52224218	20.92	Zc3h12c	zinc finger CCCH type containing 12C	55463	0.12
chr10_79874050_79875052	20.91	Plppr3	phospholipid phosphatase related 3	19	0.53
chr19_17492246_17492464	20.85	Rfk	riboflavin kinase	94918	0.08
chr1_42686778_42686966	20.82	Pantr1	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 1	6221	0.15
chr15_24567016_24567356	20.75	Gm48920	predicted gene, 48920	38292	0.19
chr15_25364173_25365245	20.64	4930445E18Rik	RIKEN cDNA 4930445E18 gene	32050	0.14
chr4_141335224_141335761	20.63	Gm25690	predicted gene, 25690	10672	0.09
chr7_79590405_79591230	20.52	Gm45169	predicted gene 45169	1796	0.2
chr19_21789708_21790094	20.51	Cemip2	cell migration inducing hyaluronidase 2	11513	0.21
chr3_139885937_139886924	20.48	Gm43678	predicted gene 43678	73666	0.11
chr18_81251894_81252538	20.46	Gm30192	predicted gene, 30192	12475	0.22
chr13_71148802_71148994	20.46	Mir466f-4	microRNA 466f-4	41809	0.19
chr8_12486572_12486996	20.45	4933439N14Rik	RIKEN cDNA 4933439N14 gene	16115	0.15
chr4_82690701_82691000	20.37	Gm11269	predicted gene 11269	1955	0.35
chr7_49018514_49018702	20.34	Gm45207	predicted gene 45207	43973	0.12
chr2_146324969_146325239	20.31	Gm14117	predicted gene 14117	19557	0.21
chr14_93009566_93009910	20.28	Gm48963	predicted gene, 48963	117036	0.06
chr11_88585153_88585378	20.27	Msi2	musashi RNA-binding protein 2	4882	0.29
chr11_58948518_58949018	20.19	H2bu2	H2B.U histone 2	152	0.86
chr15_67245652_67245820	20.15	1700012I11Rik	RIKEN cDNA 1700012I11 gene	18967	0.26
chr8_45508006_45508255	20.14	Sorbs2	sorbin and SH3 domain containing 2	212	0.94
chr12_44329338_44330111	20.12	Nrcam	neuronal cell adhesion molecule	474	0.8
chr10_20285369_20285909	20.11	Gm48249	predicted gene, 48249	987	0.4
chr13_8333561_8334203	20.09	Gm48260	predicted gene, 48260	34739	0.14
chr18_62868650_62868901	20.08	Gm50128	predicted gene, 50128	53326	0.12
chr6_61042953_61043250	20.04	Gm43892	predicted gene, 43892	1892	0.33
chr7_4123736_4124170	20.01	Ttyh1	tweety family member 1	536	0.57
chr12_86787306_86787470	19.94	Lrrc74a	leucine rich repeat containing 74A	46381	0.11
chr7_62416271_62416450	19.93	Mkrn3	makorin, ring finger protein, 3	3779	0.19
chr18_26753599_26753876	19.90	Gm49976	predicted gene, 49976	164360	0.04
chr13_71690114_71690396	19.88	Gm47812	predicted gene, 47812	65227	0.12
chr6_86028659_86028835	19.87	Add2	adducin 2 (beta)	0	0.96
chr8_48458356_48458774	19.81	Tenm3	teneurin transmembrane protein 3	96748	0.08
chr13_84783122_84783632	19.81	Gm26913	predicted gene, 26913	92436	0.09
chr12_116919674_116920700	19.71	Gm48119	predicted gene, 48119	67085	0.14
chr14_79773979_79774403	19.70	Pcdh8	protocadherin 8	2879	0.2
chr13_12650037_12651101	19.65	Gpr137b-ps	G protein-coupled receptor 137B, pseudogene	181	0.91
chr13_113918235_113918418	19.64	Arl15	ADP-ribosylation factor-like 15	123704	0.05
chr2_180854971_180855595	19.61	Gm14339	predicted gene 14339	7631	0.11
chr2_76029370_76029626	19.51	Pde11a	phosphodiesterase 11A	23455	0.18
chr4_39345030_39345334	19.50	Gm23607	predicted gene, 23607	49719	0.14
chr14_24617341_24617911	19.48	4930428N03Rik	RIKEN cDNA 4930428N03 gene	58	0.64
chr13_83868824_83869019	19.47	2810049E08Rik	RIKEN cDNA 2810049E08 gene	22287	0.18
chr18_67497794_67498327	19.38	Spire1	spire type actin nucleation factor 1	331	0.86
chr13_83885160_83885448	19.24	2810049E08Rik	RIKEN cDNA 2810049E08 gene	5904	0.23
chr11_14181939_14182516	19.15	4930554G24Rik	RIKEN cDNA 4930554G24 gene	3186	0.33
chr5_85239463_85240008	19.15	Gm21006	predicted gene, 21006	372890	0.01
chr14_70076721_70076985	19.05	Egr3	early growth response 3	350	0.85
chr8_47218091_47218404	19.02	Stox2	storkhead box 2	1946	0.35
chr4_57091378_57091763	19.01	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	11883	0.23
chr12_111693687_111693960	18.97	Gm36635	predicted gene, 36635	9259	0.09
chrX_13346707_13347908	18.96	Gm7129	predicted gene 7129	20288	0.14
chr15_103519338_103519794	18.95	Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	4152	0.16
chr13_42709847_42710338	18.95	Phactr1	phosphatase and actin regulator 1	511	0.85
chr8_35933319_35934071	18.91	Gm22030	predicted gene, 22030	43883	0.13
chr2_22029112_22029317	18.90	Gm13337	predicted gene 13337	38612	0.22
chr4_12263404_12263560	18.88	Gm11846	predicted gene 11846	7917	0.21
chr3_102979946_102980141	18.87	Sike1	suppressor of IKBKE 1	15665	0.12
chr14_7749491_7749764	18.81	Gm16741	predicted gene, 16741	318	0.87
chr1_132739219_132739652	18.79	Nfasc	neurofascin	2322	0.3
chr8_86385246_86385589	18.73	Gm24490	predicted gene, 24490	92916	0.08
chr14_118416177_118416529	18.70	Gm5672	predicted gene 5672	40159	0.12
chr12_111758304_111760062	18.67	Klc1	kinesin light chain 1	170	0.91
chr3_55373721_55374118	18.61	Dclk1	doublecortin-like kinase 1	19785	0.15
chr1_63819909_63820082	18.59	Gm13751	predicted gene 13751	25583	0.16
chr14_78383257_78383728	18.56	Gm26197	predicted gene, 26197	72152	0.09
chr10_108580885_108581405	18.53	Syt1	synaptotagmin I	55819	0.14
chr16_77787854_77788233	18.50	Gm17333	predicted gene, 17333	58561	0.11
chr5_53525618_53525873	18.50	Gm10441	predicted gene 10441	3014	0.26
chr5_44537719_44537895	18.46	Ldb2	LIM domain binding 2	2710	0.2
chr6_55791826_55792546	18.43	Itprid1	ITPR interacting domain containing 1	44709	0.18
chr9_66933818_66934187	18.42	Rps27l	ribosomal protein S27-like	12084	0.15
chr2_131847315_131847793	18.36	5330413P13Rik	RIKEN cDNA 5330413P13 gene	69	0.93
chr4_100973634_100974412	18.32	Cachd1	cache domain containing 1	20588	0.19
chr2_63273724_63274213	18.27	Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	89681	0.09
chr13_18281120_18281485	18.26	Pou6f2	POU domain, class 6, transcription factor 2	94816	0.08
chr1_82474542_82474693	18.18	Gm28940	predicted gene 28940	71871	0.08
chr18_25378079_25378424	18.17	Gm16558	predicted gene 16558	13550	0.27
chr8_92134225_92134404	18.16	Gm45332	predicted gene 45332	23952	0.17
chr9_84033065_84033577	18.14	Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	2519	0.29
chrX_143654722_143655126	18.11	Pak3	p21 (RAC1) activated kinase 3	9366	0.3
chr14_119513370_119513775	18.11	Gm6212	predicted gene 6212	130440	0.05
chr14_103764083_103764411	18.10	Slain1os	SLAIN motif family, member 1, opposite strand	64805	0.11
chr2_165136026_165136418	18.08	Gm14397	predicted gene 14397	23190	0.14
chr2_21010740_21011090	18.07	Gm13375	predicted gene 13375	41861	0.14
chr15_78835129_78836581	18.05	Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	6769	0.09
chr16_77400634_77400819	17.99	Gm21816	predicted gene, 21816	121	0.94
chr14_64489462_64489613	17.97	Msra	methionine sulfoxide reductase A	33634	0.16
chr3_138854704_138854876	17.95	Tspan5	tetraspanin 5	5703	0.23
chr13_51229149_51229565	17.93	Gm29787	predicted gene, 29787	23246	0.14
chr18_27956389_27956743	17.92	Gm33674	predicted gene, 33674	146834	0.05
chr14_24618263_24618731	17.92	4930428N03Rik	RIKEN cDNA 4930428N03 gene	534	0.66
chr10_52877516_52878175	17.90	Gm25664	predicted gene, 25664	27793	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.4	55.3	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
12.7	38.2	GO:0003358	noradrenergic neuron development(GO:0003358)
11.5	45.9	GO:0060486	Clara cell differentiation(GO:0060486)
10.5	31.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
9.3	28.0	GO:0032289	central nervous system myelin formation(GO:0032289)
9.3	37.0	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
9.2	55.1	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
9.0	27.1	GO:0010643	cell communication by chemical coupling(GO:0010643)
8.7	26.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
8.3	25.0	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
7.8	46.5	GO:1904424	regulation of GTP binding(GO:1904424)
7.6	84.0	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
7.5	37.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
7.1	28.6	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
6.9	20.7	GO:0060594	mammary gland specification(GO:0060594)
6.9	27.6	GO:0060221	retinal rod cell differentiation(GO:0060221)
6.8	20.5	GO:1901529	positive regulation of anion channel activity(GO:1901529)
6.8	47.8	GO:0045161	neuronal ion channel clustering(GO:0045161)
6.6	19.9	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
6.5	6.5	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
6.4	19.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
6.3	6.3	GO:0035973	aggrephagy(GO:0035973)
6.2	6.2	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
6.2	24.8	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
6.1	18.2	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
6.0	6.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
6.0	18.1	GO:0071873	response to norepinephrine(GO:0071873)
6.0	6.0	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
6.0	23.9	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
5.8	35.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
5.7	34.4	GO:0016198	axon choice point recognition(GO:0016198)
5.7	17.2	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
5.6	22.5	GO:0006538	glutamate catabolic process(GO:0006538)
5.6	16.8	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
5.6	11.2	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
5.6	44.4	GO:0021860	pyramidal neuron development(GO:0021860)
5.5	22.2	GO:0030035	microspike assembly(GO:0030035)
5.5	121.6	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
5.4	10.9	GO:0035434	copper ion transmembrane transport(GO:0035434)
5.4	21.7	GO:0007412	axon target recognition(GO:0007412)
5.4	27.0	GO:0042297	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
5.3	42.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
5.3	21.2	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
5.2	10.4	GO:0097091	synaptic vesicle clustering(GO:0097091)
5.2	5.2	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
5.1	10.2	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
5.1	25.4	GO:0000160	phosphorelay signal transduction system(GO:0000160)
5.1	10.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
5.0	20.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
5.0	54.5	GO:0097120	receptor localization to synapse(GO:0097120)
4.9	14.6	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
4.8	14.5	GO:1900368	regulation of RNA interference(GO:1900368)
4.8	14.3	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
4.7	19.0	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
4.7	14.2	GO:0021564	vagus nerve development(GO:0021564)
4.7	14.0	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
4.6	23.1	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
4.6	27.6	GO:0035881	amacrine cell differentiation(GO:0035881)
4.6	13.8	GO:0061743	motor learning(GO:0061743)
4.6	13.7	GO:0061551	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
4.6	13.7	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
4.5	4.5	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
4.5	4.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
4.5	8.9	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
4.5	17.9	GO:0007258	JUN phosphorylation(GO:0007258)
4.5	13.4	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
4.4	8.8	GO:0061642	chemoattraction of axon(GO:0061642)
4.4	13.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
4.2	12.7	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
4.2	8.4	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
4.2	33.4	GO:0046069	cGMP catabolic process(GO:0046069)
4.1	12.4	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
4.1	40.5	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
4.0	28.3	GO:0042473	outer ear morphogenesis(GO:0042473)
4.0	8.1	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
4.0	12.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
4.0	12.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
3.9	11.8	GO:0097503	sialylation(GO:0097503)
3.9	11.8	GO:0070634	transepithelial ammonium transport(GO:0070634)
3.8	11.4	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
3.8	15.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
3.8	7.5	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
3.8	11.3	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
3.7	7.5	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
3.7	7.4	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
3.7	14.8	GO:0033564	anterior/posterior axon guidance(GO:0033564)
3.7	18.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
3.6	14.6	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
3.6	7.3	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
3.6	58.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
3.6	47.2	GO:0007096	regulation of exit from mitosis(GO:0007096)
3.6	14.5	GO:0046959	habituation(GO:0046959)
3.6	10.9	GO:0046103	inosine biosynthetic process(GO:0046103)
3.6	7.2	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
3.6	10.7	GO:0046684	response to pyrethroid(GO:0046684)
3.5	24.8	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
3.5	42.4	GO:0048268	clathrin coat assembly(GO:0048268)
3.5	7.0	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
3.5	17.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
3.5	51.9	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
3.4	6.9	GO:0060166	olfactory pit development(GO:0060166)
3.4	10.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
3.4	6.8	GO:0035262	gonad morphogenesis(GO:0035262)
3.4	6.8	GO:1904861	excitatory synapse assembly(GO:1904861)
3.4	10.2	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
3.4	10.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
3.4	10.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
3.4	3.4	GO:1902896	terminal web assembly(GO:1902896)
3.3	23.2	GO:0071625	vocalization behavior(GO:0071625)
3.3	9.9	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
3.2	9.7	GO:0030070	insulin processing(GO:0030070)
3.2	9.7	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
3.2	28.9	GO:0071803	positive regulation of podosome assembly(GO:0071803)
3.2	6.4	GO:0072318	clathrin coat disassembly(GO:0072318)
3.2	9.5	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
3.1	9.4	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
3.1	9.4	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
3.1	3.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
3.1	3.1	GO:0071435	potassium ion export(GO:0071435)
3.1	27.5	GO:0035418	protein localization to synapse(GO:0035418)
3.0	9.1	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
2.9	8.8	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
2.9	8.8	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
2.9	14.5	GO:0022038	corpus callosum development(GO:0022038)
2.9	17.4	GO:0048840	otolith development(GO:0048840)
2.9	8.6	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
2.9	8.6	GO:0097154	GABAergic neuron differentiation(GO:0097154)
2.9	5.7	GO:0089700	protein kinase D signaling(GO:0089700)
2.8	90.4	GO:0019228	neuronal action potential(GO:0019228)
2.8	19.8	GO:0042118	endothelial cell activation(GO:0042118)
2.8	14.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
2.8	11.2	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
2.8	5.6	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
2.8	11.1	GO:0023041	neuronal signal transduction(GO:0023041)
2.8	8.3	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
2.8	8.3	GO:0032512	regulation of protein phosphatase type 2B activity(GO:0032512)
2.7	24.7	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
2.7	5.4	GO:0051665	membrane raft localization(GO:0051665)
2.7	8.0	GO:0008228	opsonization(GO:0008228)
2.7	8.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.7	5.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
2.6	23.8	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.6	7.8	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
2.6	7.7	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
2.6	10.3	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
2.6	25.8	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
2.6	7.7	GO:0036438	maintenance of lens transparency(GO:0036438)
2.6	5.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
2.5	10.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.5	2.5	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
2.5	2.5	GO:0098597	observational learning(GO:0098597)
2.5	5.1	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
2.5	2.5	GO:0097104	postsynaptic membrane assembly(GO:0097104)
2.5	15.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
2.5	7.5	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
2.5	10.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
2.5	42.5	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
2.5	20.0	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
2.5	27.4	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
2.5	10.0	GO:0002051	osteoblast fate commitment(GO:0002051)
2.5	2.5	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
2.5	4.9	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
2.5	7.4	GO:0060437	lung growth(GO:0060437)
2.5	22.1	GO:0008038	neuron recognition(GO:0008038)
2.4	7.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
2.4	7.2	GO:0072697	protein localization to cell cortex(GO:0072697)
2.4	9.6	GO:0001927	exocyst assembly(GO:0001927)
2.4	7.2	GO:0014042	positive regulation of neuron maturation(GO:0014042)
2.4	23.9	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
2.4	2.4	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.3	4.7	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
2.3	11.6	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
2.3	6.9	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
2.3	9.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
2.3	4.6	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
2.3	11.4	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
2.3	6.8	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
2.2	8.9	GO:0010042	response to manganese ion(GO:0010042)
2.2	8.9	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
2.2	2.2	GO:0007621	negative regulation of female receptivity(GO:0007621)
2.2	4.5	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
2.2	15.6	GO:0060013	righting reflex(GO:0060013)
2.2	22.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
2.2	8.8	GO:0048852	diencephalon morphogenesis(GO:0048852)
2.2	8.8	GO:0060278	regulation of ovulation(GO:0060278)
2.2	13.2	GO:0072178	nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
2.2	4.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
2.2	24.0	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
2.2	2.2	GO:0001661	conditioned taste aversion(GO:0001661)
2.2	15.2	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.2	6.5	GO:0030382	sperm mitochondrion organization(GO:0030382)
2.2	13.0	GO:0060997	dendritic spine morphogenesis(GO:0060997)
2.2	2.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
2.2	8.6	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
2.1	14.9	GO:0051764	actin crosslink formation(GO:0051764)
2.1	6.4	GO:0021979	hypothalamus cell differentiation(GO:0021979)
2.1	2.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.1	2.1	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
2.1	6.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.1	10.4	GO:0008354	germ cell migration(GO:0008354)
2.1	6.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
2.1	4.1	GO:2000821	regulation of grooming behavior(GO:2000821)
2.1	10.3	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
2.1	6.2	GO:0021698	cerebellar cortex structural organization(GO:0021698)
2.0	30.4	GO:0060074	synapse maturation(GO:0060074)
2.0	4.0	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
2.0	2.0	GO:0097212	lysosomal membrane organization(GO:0097212)
2.0	4.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.0	2.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
2.0	3.9	GO:0019230	proprioception(GO:0019230)
2.0	7.8	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.0	7.8	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.9	7.8	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.9	9.7	GO:0010996	response to auditory stimulus(GO:0010996)
1.9	5.8	GO:2001025	positive regulation of response to drug(GO:2001025)
1.9	7.7	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
1.9	5.8	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.9	11.5	GO:0051694	pointed-end actin filament capping(GO:0051694)
1.9	13.4	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
1.9	11.4	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
1.9	3.8	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
1.9	3.8	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.9	5.7	GO:0048239	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
1.9	3.8	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
1.9	1.9	GO:0021544	subpallium development(GO:0021544) striatum development(GO:0021756)
1.9	14.9	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.9	3.7	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.8	3.7	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
1.8	11.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
1.8	1.8	GO:0003406	retinal pigment epithelium development(GO:0003406)
1.8	20.2	GO:0060384	innervation(GO:0060384)
1.8	9.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
1.8	7.3	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
1.8	25.3	GO:0003417	growth plate cartilage development(GO:0003417)
1.8	9.0	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
1.8	1.8	GO:1904181	positive regulation of membrane depolarization(GO:1904181)
1.8	1.8	GO:0048807	female genitalia morphogenesis(GO:0048807)
1.8	5.4	GO:0098828	modulation of inhibitory postsynaptic potential(GO:0098828)
1.8	1.8	GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
1.8	19.5	GO:0060081	membrane hyperpolarization(GO:0060081)
1.8	1.8	GO:0090427	activation of meiosis(GO:0090427)
1.8	3.5	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
1.8	5.3	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.8	7.0	GO:0014028	notochord formation(GO:0014028)
1.8	12.3	GO:0021542	dentate gyrus development(GO:0021542)
1.8	3.5	GO:0021794	thalamus development(GO:0021794)
1.7	1.7	GO:0030432	peristalsis(GO:0030432)
1.7	5.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
1.7	3.5	GO:0016080	synaptic vesicle targeting(GO:0016080)
1.7	5.2	GO:0006532	aspartate biosynthetic process(GO:0006532)
1.7	5.2	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
1.7	1.7	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
1.7	1.7	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.7	5.1	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
1.7	13.7	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.7	5.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.7	3.4	GO:0007386	compartment pattern specification(GO:0007386)
1.7	3.4	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
1.7	3.3	GO:0003150	muscular septum morphogenesis(GO:0003150)
1.7	1.7	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.7	8.3	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.7	1.7	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
1.7	6.6	GO:0048739	cardiac muscle fiber development(GO:0048739)
1.7	9.9	GO:2001224	positive regulation of neuron migration(GO:2001224)
1.6	3.3	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
1.6	4.9	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
1.6	8.1	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
1.6	8.1	GO:0015808	L-alanine transport(GO:0015808)
1.6	24.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
1.6	19.2	GO:0001964	startle response(GO:0001964)
1.6	8.0	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
1.6	3.2	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.6	3.2	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
1.6	6.3	GO:0030091	protein repair(GO:0030091)
1.6	1.6	GO:0072172	ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
1.6	40.6	GO:0021954	central nervous system neuron development(GO:0021954)
1.6	3.1	GO:0030421	defecation(GO:0030421)
1.6	4.7	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
1.6	12.4	GO:0015816	glycine transport(GO:0015816)
1.6	4.7	GO:2000195	negative regulation of female gonad development(GO:2000195)
1.5	4.6	GO:0003344	pericardium morphogenesis(GO:0003344)
1.5	4.6	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
1.5	15.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
1.5	3.0	GO:0060178	regulation of exocyst localization(GO:0060178)
1.5	6.0	GO:0016584	nucleosome positioning(GO:0016584)
1.5	4.5	GO:0071492	cellular response to UV-A(GO:0071492)
1.5	25.2	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.5	5.9	GO:0048681	negative regulation of axon regeneration(GO:0048681)
1.5	2.9	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
1.5	4.4	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.5	10.3	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
1.5	23.4	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.5	10.2	GO:0046851	negative regulation of bone remodeling(GO:0046851)
1.5	5.8	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
1.4	1.4	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.4	1.4	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
1.4	52.4	GO:0051965	positive regulation of synapse assembly(GO:0051965)
1.4	2.8	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
1.4	12.6	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
1.4	8.4	GO:0060004	reflex(GO:0060004)
1.4	2.7	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.4	5.4	GO:0010587	miRNA catabolic process(GO:0010587)
1.4	4.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
1.4	14.9	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
1.3	5.4	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.3	1.3	GO:1904023	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
1.3	2.6	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
1.3	7.8	GO:0001504	neurotransmitter uptake(GO:0001504)
1.3	9.1	GO:0060736	prostate gland growth(GO:0060736)
1.3	2.6	GO:0070253	somatostatin secretion(GO:0070253)
1.3	3.9	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.3	36.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.3	6.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.3	2.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
1.3	20.1	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
1.3	2.5	GO:0072093	metanephric renal vesicle formation(GO:0072093)
1.3	5.0	GO:1903887	motile primary cilium assembly(GO:1903887)
1.3	12.5	GO:0060749	mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
1.2	3.7	GO:0030157	pancreatic juice secretion(GO:0030157)
1.2	2.5	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
1.2	7.5	GO:0015074	DNA integration(GO:0015074)
1.2	5.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
1.2	2.5	GO:2000019	negative regulation of male gonad development(GO:2000019)
1.2	16.1	GO:0035640	exploration behavior(GO:0035640)
1.2	2.5	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.2	2.5	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
1.2	2.5	GO:0090135	actin filament branching(GO:0090135)
1.2	1.2	GO:2000412	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
1.2	1.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
1.2	1.2	GO:0003180	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
1.2	3.6	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
1.2	3.6	GO:0008090	retrograde axonal transport(GO:0008090)
1.2	8.4	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.2	15.5	GO:0030322	stabilization of membrane potential(GO:0030322)
1.2	4.8	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
1.2	4.7	GO:0043615	astrocyte cell migration(GO:0043615)
1.2	4.7	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
1.2	3.5	GO:0005513	detection of calcium ion(GO:0005513)
1.2	2.3	GO:0048664	neuron fate determination(GO:0048664)
1.2	1.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
1.2	3.5	GO:0048696	collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
1.2	1.2	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
1.2	1.2	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.2	5.8	GO:0060539	diaphragm development(GO:0060539)
1.2	5.8	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
1.1	3.4	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
1.1	3.4	GO:0033693	neurofilament bundle assembly(GO:0033693)
1.1	5.7	GO:0060179	male mating behavior(GO:0060179)
1.1	5.7	GO:0021854	hypothalamus development(GO:0021854)
1.1	4.5	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
1.1	6.7	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
1.1	7.7	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.1	1.1	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
1.1	3.3	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.1	1.1	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
1.1	1.1	GO:0003096	renal sodium ion transport(GO:0003096)
1.1	4.4	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.1	5.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
1.1	2.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.1	7.6	GO:0050765	negative regulation of phagocytosis(GO:0050765)
1.1	18.4	GO:0007616	long-term memory(GO:0007616)
1.1	2.2	GO:1903998	regulation of eating behavior(GO:1903998)
1.1	6.5	GO:0060068	vagina development(GO:0060068)
1.1	3.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
1.1	75.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.1	3.2	GO:0090148	membrane fission(GO:0090148)
1.1	31.1	GO:0050885	neuromuscular process controlling balance(GO:0050885)
1.1	3.2	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.1	3.2	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
1.1	1.1	GO:0015705	iodide transport(GO:0015705)
1.1	1.1	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
1.1	19.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
1.1	5.3	GO:0031468	nuclear envelope reassembly(GO:0031468)
1.0	27.1	GO:0007340	acrosome reaction(GO:0007340)
1.0	1.0	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.0	10.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.0	4.1	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
1.0	7.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
1.0	2.0	GO:0010966	regulation of phosphate transport(GO:0010966)
1.0	9.1	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.0	17.1	GO:0007416	synapse assembly(GO:0007416)
1.0	3.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
1.0	11.0	GO:0009404	toxin metabolic process(GO:0009404)
1.0	2.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
1.0	4.0	GO:0031034	myosin filament assembly(GO:0031034)
1.0	4.0	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
1.0	2.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
1.0	7.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.0	2.9	GO:0007638	mechanosensory behavior(GO:0007638)
1.0	6.8	GO:0006108	malate metabolic process(GO:0006108)
1.0	9.6	GO:2001222	regulation of neuron migration(GO:2001222)
1.0	2.9	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
1.0	2.9	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
1.0	1.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.9	2.8	GO:0006667	sphinganine metabolic process(GO:0006667)
0.9	0.9	GO:2000018	regulation of male gonad development(GO:2000018)
0.9	4.7	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.9	6.5	GO:0070986	left/right axis specification(GO:0070986)
0.9	2.8	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.9	13.0	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9	0.9	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.9	1.8	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.9	3.7	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.9	3.6	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.9	2.7	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.9	5.4	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.9	8.1	GO:0001967	suckling behavior(GO:0001967)
0.9	2.7	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.9	8.9	GO:0060292	long term synaptic depression(GO:0060292)
0.9	8.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.9	4.4	GO:0033762	response to glucagon(GO:0033762)
0.9	6.1	GO:0015858	nucleoside transport(GO:0015858)
0.9	2.6	GO:0009233	menaquinone metabolic process(GO:0009233)
0.9	2.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.9	2.6	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.9	0.9	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.9	4.3	GO:0051095	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.9	1.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.9	1.7	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.9	5.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.9	3.4	GO:0070365	hepatocyte differentiation(GO:0070365)
0.8	4.2	GO:0072675	osteoclast fusion(GO:0072675)
0.8	2.5	GO:0000733	DNA strand renaturation(GO:0000733)
0.8	2.5	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.8	6.7	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.8	11.7	GO:0019226	transmission of nerve impulse(GO:0019226)
0.8	0.8	GO:0070672	response to interleukin-15(GO:0070672)
0.8	8.3	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.8	3.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.8	2.4	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.8	3.2	GO:0035627	ceramide transport(GO:0035627)
0.8	1.6	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.8	1.6	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.8	4.8	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.8	1.6	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.8	1.6	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.8	6.4	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.8	14.4	GO:0001573	ganglioside metabolic process(GO:0001573)
0.8	3.2	GO:0003416	endochondral bone growth(GO:0003416)
0.8	0.8	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.8	2.3	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8	2.3	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.8	0.8	GO:0021871	forebrain regionalization(GO:0021871)
0.8	0.8	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.8	2.3	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.8	0.8	GO:0035995	detection of muscle stretch(GO:0035995)
0.8	5.3	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.8	3.8	GO:0001778	plasma membrane repair(GO:0001778)
0.7	17.2	GO:0007632	visual behavior(GO:0007632)
0.7	2.2	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.7	0.7	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.7	1.5	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.7	4.4	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.7	2.9	GO:0032836	glomerular basement membrane development(GO:0032836)
0.7	0.7	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.7	6.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7	3.6	GO:0042989	sequestering of actin monomers(GO:0042989)
0.7	2.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.7	0.7	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.7	2.9	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.7	1.4	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.7	2.8	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.7	0.7	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.7	1.4	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.7	5.5	GO:0036093	germ cell proliferation(GO:0036093)
0.7	2.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7	5.5	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7	3.4	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.7	1.4	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.7	2.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.7	0.7	GO:0048793	pronephros development(GO:0048793)
0.7	2.0	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.7	3.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7	2.0	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
0.7	1.3	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.7	1.3	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.7	0.7	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.7	3.3	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.7	2.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.7	2.6	GO:0019348	dolichol metabolic process(GO:0019348)
0.7	2.0	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.7	0.7	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.6	1.3	GO:0030222	eosinophil differentiation(GO:0030222)
0.6	2.6	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.6	10.3	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.6	0.6	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.6	3.2	GO:0046548	retinal rod cell development(GO:0046548)
0.6	3.8	GO:0051503	adenine nucleotide transport(GO:0051503)
0.6	1.9	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.6	0.6	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.6	5.7	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.6	1.9	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.6	1.3	GO:0008292	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.6	1.8	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.6	4.8	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.6	4.8	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.6	1.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.6	5.4	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.6	1.2	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.6	0.6	GO:0001975	response to amphetamine(GO:0001975)
0.6	0.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.6	1.8	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.6	45.8	GO:0097485	neuron projection guidance(GO:0097485)
0.6	5.2	GO:0045056	transcytosis(GO:0045056)
0.6	0.6	GO:0000189	MAPK import into nucleus(GO:0000189)
0.6	3.5	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.6	1.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.6	1.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.6	1.1	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.6	0.6	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.6	2.2	GO:0033227	dsRNA transport(GO:0033227)
0.6	1.1	GO:0065001	specification of axis polarity(GO:0065001)
0.6	2.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.5	1.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.5	4.9	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5	3.3	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.5	3.8	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5	1.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.5	8.9	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.5	0.5	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.5	2.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.5	1.0	GO:0042891	antibiotic transport(GO:0042891)
0.5	0.5	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.5	4.1	GO:0016048	detection of temperature stimulus(GO:0016048)
0.5	3.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.5	3.1	GO:0034453	microtubule anchoring(GO:0034453)
0.5	1.5	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.5	4.6	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.5	4.6	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.5	0.5	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.5	2.0	GO:2000035	regulation of stem cell division(GO:2000035)
0.5	1.5	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.5	2.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.5	3.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.5	0.5	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.5	1.0	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.5	1.5	GO:0006597	spermine biosynthetic process(GO:0006597)
0.5	5.8	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.5	37.0	GO:0007626	locomotory behavior(GO:0007626)
0.5	2.9	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.5	1.0	GO:0070459	prolactin secretion(GO:0070459)
0.5	0.9	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5	1.9	GO:0006566	threonine metabolic process(GO:0006566)
0.5	0.5	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.5	3.7	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.5	10.3	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.5	0.9	GO:0051788	response to misfolded protein(GO:0051788)
0.5	0.5	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.5	1.4	GO:0015889	cobalamin transport(GO:0015889)
0.5	0.9	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.4	1.8	GO:0035092	sperm chromatin condensation(GO:0035092)
0.4	3.6	GO:0048745	smooth muscle tissue development(GO:0048745)
0.4	3.6	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.4	6.6	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4	0.4	GO:1902805	positive regulation of synaptic vesicle transport(GO:1902805)
0.4	0.4	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.4	4.3	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.4	3.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4	0.4	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.4	6.9	GO:0030488	tRNA methylation(GO:0030488)
0.4	17.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.4	0.4	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4	1.7	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.4	0.4	GO:1903975	regulation of glial cell migration(GO:1903975)
0.4	1.6	GO:0015813	L-glutamate transport(GO:0015813)
0.4	0.8	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.4	0.8	GO:0035989	tendon development(GO:0035989)
0.4	2.5	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.4	3.7	GO:0006266	DNA ligation(GO:0006266)
0.4	0.4	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.4	5.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.4	2.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.4	6.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.4	0.8	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.4	2.8	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.4	0.4	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.4	2.4	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.4	2.0	GO:0051451	myoblast migration(GO:0051451)
0.4	1.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4	6.6	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.4	1.9	GO:0016082	synaptic vesicle priming(GO:0016082)
0.4	8.8	GO:0021987	cerebral cortex development(GO:0021987)
0.4	0.4	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.4	0.8	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.4	2.3	GO:0042474	middle ear morphogenesis(GO:0042474)
0.4	1.1	GO:0036376	sodium ion export from cell(GO:0036376)
0.4	0.4	GO:0060460	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.4	2.2	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4	1.5	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.4	0.7	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.4	1.5	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4	1.5	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.4	0.7	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.4	1.5	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4	2.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.4	1.8	GO:0009235	cobalamin metabolic process(GO:0009235)
0.4	0.4	GO:0014738	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.4	0.4	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.3	1.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.3	1.0	GO:0050654	chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.3	1.0	GO:0033026	negative regulation of mast cell apoptotic process(GO:0033026)
0.3	0.7	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.3	1.4	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3	0.3	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.3	1.4	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.3	0.7	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3	7.4	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.3	0.3	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.3	0.3	GO:0036257	multivesicular body organization(GO:0036257)
0.3	0.3	GO:0072198	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
0.3	0.3	GO:0072205	metanephric collecting duct development(GO:0072205)
0.3	4.0	GO:0007019	microtubule depolymerization(GO:0007019)
0.3	0.3	GO:0005984	disaccharide metabolic process(GO:0005984)
0.3	2.6	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.3	0.3	GO:0036006	response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.3	2.3	GO:0010842	retina layer formation(GO:0010842)
0.3	2.6	GO:0032835	glomerulus development(GO:0032835)
0.3	1.3	GO:1903333	negative regulation of protein folding(GO:1903333)
0.3	1.0	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.3	0.7	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.3	0.6	GO:0046952	ketone body catabolic process(GO:0046952)
0.3	1.6	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.3	0.6	GO:0035810	positive regulation of urine volume(GO:0035810)
0.3	0.6	GO:0042048	olfactory behavior(GO:0042048)
0.3	9.9	GO:0099643	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.3	1.9	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.3	0.6	GO:0009957	epidermal cell fate specification(GO:0009957)
0.3	0.9	GO:0046379	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3	0.6	GO:0097070	ductus arteriosus closure(GO:0097070)
0.3	0.9	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.3	5.9	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.3	2.8	GO:0000103	sulfate assimilation(GO:0000103)
0.3	1.5	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3	0.6	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.3	0.9	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.3	0.9	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.3	6.2	GO:0034605	cellular response to heat(GO:0034605)
0.3	0.3	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.3	0.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3	0.6	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.3	0.9	GO:0072498	embryonic skeletal joint development(GO:0072498)
0.3	0.3	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.3	0.8	GO:0008306	associative learning(GO:0008306)
0.3	0.6	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3	0.8	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.3	2.2	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.3	4.4	GO:0010107	potassium ion import(GO:0010107)
0.3	1.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.3	0.3	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3	0.5	GO:0048853	forebrain morphogenesis(GO:0048853)
0.3	1.6	GO:0006983	ER overload response(GO:0006983)
0.3	2.9	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.3	0.5	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.3	1.3	GO:0071569	protein ufmylation(GO:0071569)
0.3	0.8	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.3	0.3	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.3	1.3	GO:0071397	cellular response to cholesterol(GO:0071397)
0.3	0.8	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3	0.8	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3	0.5	GO:0042940	D-amino acid transport(GO:0042940)
0.3	0.8	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.3	1.0	GO:0008347	glial cell migration(GO:0008347)
0.2	0.2	GO:0048859	formation of anatomical boundary(GO:0048859)
0.2	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.2	5.9	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2	2.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.2	0.5	GO:0035697	CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.2	0.5	GO:0008089	anterograde axonal transport(GO:0008089)
0.2	0.5	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	1.7	GO:0045076	regulation of interleukin-2 biosynthetic process(GO:0045076)
0.2	0.2	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.2	0.2	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2	1.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	0.5	GO:0010446	response to alkaline pH(GO:0010446)
0.2	0.9	GO:0042220	response to cocaine(GO:0042220)
0.2	0.7	GO:0016068	regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.2	0.4	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.2	0.4	GO:0006382	adenosine to inosine editing(GO:0006382)
0.2	1.0	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2	0.6	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.2	0.2	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2	1.6	GO:1990173	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2	1.0	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	0.2	GO:0032276	regulation of gonadotropin secretion(GO:0032276)
0.2	0.2	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.2	0.4	GO:0070268	cornification(GO:0070268)
0.2	0.2	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.2	0.6	GO:0044065	regulation of respiratory system process(GO:0044065)
0.2	2.3	GO:0000281	mitotic cytokinesis(GO:0000281)
0.2	0.4	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.2	1.0	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.2	0.6	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.2	1.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.2	0.5	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	2.9	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.2	0.5	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.2	0.2	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	0.3	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.2	3.9	GO:0072384	organelle transport along microtubule(GO:0072384)
0.2	0.8	GO:0071800	podosome assembly(GO:0071800)
0.2	0.3	GO:0007341	penetration of zona pellucida(GO:0007341)
0.2	0.6	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2	3.9	GO:0008333	endosome to lysosome transport(GO:0008333)
0.2	0.5	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.2	0.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.2	0.3	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.2	0.3	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.6	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1	0.1	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.1	0.3	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.1	0.3	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1	0.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1	1.8	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.5	GO:0070314	G1 to G0 transition(GO:0070314)
0.1	0.1	GO:1903208	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	1.7	GO:0048240	sperm capacitation(GO:0048240)
0.1	0.4	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.2	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.4	GO:0060988	lipid tube assembly(GO:0060988)
0.1	0.3	GO:0019086	late viral transcription(GO:0019086)
0.1	0.8	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1	0.3	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	0.2	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1	1.2	GO:0097352	autophagosome maturation(GO:0097352)
0.1	4.7	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	0.1	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.2	GO:0071242	cellular response to ammonium ion(GO:0071242)
0.1	3.5	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
0.1	0.3	GO:0044838	cell quiescence(GO:0044838)
0.1	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	0.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	1.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	1.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1	0.3	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.1	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.1	0.1	GO:0086066	atrial cardiac muscle cell action potential(GO:0086014) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
0.1	0.3	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.1	GO:0002930	trabecular meshwork development(GO:0002930) ciliary body morphogenesis(GO:0061073)
0.1	0.2	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.1	0.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.1	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.1	0.6	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1	0.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.1	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.1	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.1	0.4	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.1	0.1	GO:2001201	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1	0.6	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.1	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.1	0.4	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.1	1.2	GO:0006400	tRNA modification(GO:0006400)
0.1	0.8	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.1	GO:0060618	nipple development(GO:0060618)
0.0	1.1	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.1	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.0	GO:0038001	paracrine signaling(GO:0038001)
0.0	0.3	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.0	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.5	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.0	0.1	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.0	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	2.4	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0097012	response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.0	GO:0015865	purine nucleotide transport(GO:0015865)
0.0	0.0	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.0	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.3	GO:0051310	metaphase plate congression(GO:0051310)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	94.0	GO:0043194	axon initial segment(GO:0043194)
8.4	58.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
7.8	46.8	GO:0031258	lamellipodium membrane(GO:0031258)
6.6	19.8	GO:0072534	perineuronal net(GO:0072534)
5.8	29.2	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
5.7	51.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
4.9	49.2	GO:0035253	ciliary rootlet(GO:0035253)
4.5	13.6	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
4.3	12.9	GO:0097451	glial limiting end-foot(GO:0097451)
4.3	25.5	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
4.0	28.0	GO:0008290	F-actin capping protein complex(GO:0008290)
3.9	27.2	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
3.6	14.4	GO:0044308	axonal spine(GO:0044308)
3.5	13.9	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
3.4	10.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
3.3	9.9	GO:0033010	paranodal junction(GO:0033010)
3.2	3.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
3.2	9.5	GO:0097433	dense body(GO:0097433)
3.1	9.4	GO:0097427	microtubule bundle(GO:0097427)
3.1	12.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
3.0	53.8	GO:0060077	inhibitory synapse(GO:0060077)
3.0	11.9	GO:0008091	spectrin(GO:0008091)
2.8	5.5	GO:0044316	cone cell pedicle(GO:0044316)
2.8	22.0	GO:0042788	polysomal ribosome(GO:0042788)
2.8	27.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
2.7	59.5	GO:0048786	presynaptic active zone(GO:0048786)
2.7	10.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
2.6	7.7	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
2.5	10.2	GO:0035748	myelin sheath abaxonal region(GO:0035748)
2.5	24.8	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
2.5	19.8	GO:0071437	invadopodium(GO:0071437)
2.5	22.3	GO:0031527	filopodium membrane(GO:0031527)
2.4	9.6	GO:0005593	FACIT collagen trimer(GO:0005593)
2.4	9.6	GO:0044326	dendritic spine neck(GO:0044326)
2.4	14.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
2.3	14.1	GO:0032584	growth cone membrane(GO:0032584)
2.3	58.2	GO:0044295	axonal growth cone(GO:0044295)
2.3	15.9	GO:0043083	synaptic cleft(GO:0043083)
2.2	6.7	GO:0060053	neurofilament cytoskeleton(GO:0060053)
2.2	50.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
2.2	6.5	GO:0005608	laminin-3 complex(GO:0005608)
2.1	6.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
2.1	2.1	GO:0035838	growing cell tip(GO:0035838)
2.1	4.2	GO:0097441	basilar dendrite(GO:0097441)
2.1	20.6	GO:0032433	filopodium tip(GO:0032433)
2.0	55.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
2.0	28.3	GO:0030673	axolemma(GO:0030673)
2.0	200.3	GO:0030426	growth cone(GO:0030426)
1.8	16.6	GO:0000813	ESCRT I complex(GO:0000813)
1.8	9.1	GO:0071547	piP-body(GO:0071547)
1.8	16.4	GO:0000137	Golgi cis cisterna(GO:0000137)
1.8	25.3	GO:0043205	fibril(GO:0043205)
1.7	1.7	GO:0035749	myelin sheath adaxonal region(GO:0035749)
1.7	46.2	GO:0042734	presynaptic membrane(GO:0042734)
1.7	5.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
1.7	10.2	GO:0005859	muscle myosin complex(GO:0005859)
1.7	18.2	GO:0030061	mitochondrial crista(GO:0030061)
1.6	13.1	GO:0001520	outer dense fiber(GO:0001520)
1.6	3.1	GO:0070765	gamma-secretase complex(GO:0070765)
1.6	6.3	GO:0030314	junctional membrane complex(GO:0030314)
1.5	21.4	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.5	44.7	GO:0031594	neuromuscular junction(GO:0031594)
1.5	7.3	GO:0005579	membrane attack complex(GO:0005579)
1.4	9.9	GO:0060076	excitatory synapse(GO:0060076)
1.4	2.8	GO:0008275	gamma-tubulin small complex(GO:0008275)
1.4	4.2	GO:0048179	activin receptor complex(GO:0048179)
1.4	6.9	GO:0045098	type III intermediate filament(GO:0045098)
1.4	4.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.3	1.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.3	5.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
1.3	14.4	GO:0034704	calcium channel complex(GO:0034704)
1.3	19.5	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
1.3	160.1	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.2	3.7	GO:0042585	germinal vesicle(GO:0042585)
1.2	3.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
1.2	7.2	GO:0016012	sarcoglycan complex(GO:0016012)
1.2	12.8	GO:0042555	MCM complex(GO:0042555)
1.2	116.6	GO:0045211	postsynaptic membrane(GO:0045211)
1.2	8.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.2	11.6	GO:0005641	nuclear envelope lumen(GO:0005641)
1.1	3.4	GO:0001674	female germ cell nucleus(GO:0001674)
1.1	3.4	GO:0070552	BRISC complex(GO:0070552)
1.1	4.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
1.1	4.4	GO:0043202	lysosomal lumen(GO:0043202)
1.0	3.1	GO:0035061	interchromatin granule(GO:0035061)
1.0	16.6	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
1.0	3.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
1.0	4.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
1.0	3.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.0	6.8	GO:0033263	CORVET complex(GO:0033263)
1.0	4.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.0	4.8	GO:0016589	NURF complex(GO:0016589)
0.9	5.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.9	8.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.9	15.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.9	3.4	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.8	14.4	GO:0005614	interstitial matrix(GO:0005614)
0.8	38.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.8	2.4	GO:0000802	transverse filament(GO:0000802)
0.8	52.7	GO:0008021	synaptic vesicle(GO:0008021)
0.8	3.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.8	5.5	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7	19.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.7	5.8	GO:0060091	kinocilium(GO:0060091)
0.7	1.4	GO:1990635	proximal dendrite(GO:1990635)
0.7	2.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.7	5.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.7	2.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7	2.7	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7	7.9	GO:0042575	DNA polymerase complex(GO:0042575)
0.7	2.0	GO:0005879	axonemal microtubule(GO:0005879)
0.6	2.6	GO:0097422	tubular endosome(GO:0097422)
0.6	19.2	GO:0005921	gap junction(GO:0005921)
0.6	4.5	GO:0097440	apical dendrite(GO:0097440)
0.6	20.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.6	1.9	GO:0071797	LUBAC complex(GO:0071797)
0.6	0.6	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.6	1.8	GO:0034457	Mpp10 complex(GO:0034457)
0.6	8.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.6	5.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.6	8.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.6	1.2	GO:1990357	terminal web(GO:1990357)
0.6	2.3	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6	1.7	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6	1.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6	4.0	GO:0097542	ciliary tip(GO:0097542)
0.6	4.0	GO:0043020	NADPH oxidase complex(GO:0043020)
0.6	2.8	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6	1.1	GO:1990909	Wnt signalosome(GO:1990909)
0.5	6.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.5	117.4	GO:0030425	dendrite(GO:0030425)
0.5	1.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5	2.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5	1.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5	5.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.5	1.9	GO:0061574	ASAP complex(GO:0061574)
0.4	4.9	GO:0097431	mitotic spindle pole(GO:0097431)
0.4	1.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.4	1.8	GO:0070545	PeBoW complex(GO:0070545)
0.4	2.2	GO:0061617	MICOS complex(GO:0061617)
0.4	1.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.4	2.6	GO:0070847	core mediator complex(GO:0070847)
0.4	1.7	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.4	3.4	GO:0032797	SMN complex(GO:0032797)
0.4	1.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.4	1.5	GO:0030897	HOPS complex(GO:0030897)
0.4	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.4	11.7	GO:0043204	perikaryon(GO:0043204)
0.4	8.0	GO:0034451	centriolar satellite(GO:0034451)
0.4	4.7	GO:0035686	sperm fibrous sheath(GO:0035686)
0.3	3.0	GO:0097539	ciliary transition fiber(GO:0097539)
0.3	30.9	GO:0031225	anchored component of membrane(GO:0031225)
0.3	1.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3	1.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.3	1.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.3	1.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.3	1.9	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.3	0.3	GO:0032279	asymmetric synapse(GO:0032279)
0.3	0.8	GO:0071942	XPC complex(GO:0071942)
0.3	0.5	GO:0043511	inhibin complex(GO:0043511)
0.2	0.6	GO:0036396	MIS complex(GO:0036396)
0.2	1.1	GO:0032300	mismatch repair complex(GO:0032300)
0.2	1.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.2	1.6	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	4.6	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	0.8	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	4.4	GO:0005581	collagen trimer(GO:0005581)
0.1	0.7	GO:0097255	R2TP complex(GO:0097255)
0.1	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.6	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	1.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.5	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.4	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.4	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.6	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.4	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.5	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.7	GO:0036157	outer dynein arm(GO:0036157)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.1	1.0	GO:0001673	male germ cell nucleus(GO:0001673)
0.1	0.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	3.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	4.2	GO:0055037	recycling endosome(GO:0055037)
0.1	1.0	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.4	GO:0000124	SAGA complex(GO:0000124)
0.0	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	1.5	GO:0030027	lamellipodium(GO:0030027)
0.0	0.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	2.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
28.4	85.2	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
10.2	30.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
9.5	28.5	GO:0097109	neuroligin family protein binding(GO:0097109)
9.3	46.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
9.2	37.0	GO:0032051	clathrin light chain binding(GO:0032051)
8.8	44.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
7.9	23.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
7.6	38.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
7.6	22.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
7.4	22.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
7.2	28.9	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
7.2	28.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
6.1	30.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.7	17.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
5.5	16.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
5.4	10.8	GO:0045503	dynein light chain binding(GO:0045503)
5.3	15.9	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
5.1	25.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
5.0	29.8	GO:0004385	guanylate kinase activity(GO:0004385)
4.9	9.8	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
4.6	50.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
4.5	13.4	GO:0016882	cyclo-ligase activity(GO:0016882)
4.4	13.3	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
4.4	17.6	GO:0004065	arylsulfatase activity(GO:0004065)
4.3	30.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
4.1	16.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
4.1	12.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
4.0	47.5	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
3.9	23.7	GO:0034190	apolipoprotein receptor binding(GO:0034190)
3.9	11.8	GO:0070699	type II activin receptor binding(GO:0070699)
3.8	11.5	GO:0017002	activin-activated receptor activity(GO:0017002)
3.7	14.8	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
3.6	17.8	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
3.5	10.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
3.4	30.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
3.4	6.7	GO:0005030	neurotrophin receptor activity(GO:0005030)
3.2	15.8	GO:0042609	CD4 receptor binding(GO:0042609)
3.1	12.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
3.1	12.5	GO:0038064	collagen receptor activity(GO:0038064)
3.1	9.3	GO:0005148	prolactin receptor binding(GO:0005148)
3.1	12.4	GO:0034056	estrogen response element binding(GO:0034056)
3.1	42.9	GO:0045295	gamma-catenin binding(GO:0045295)
3.1	18.4	GO:0008046	axon guidance receptor activity(GO:0008046)
3.1	33.6	GO:0005522	profilin binding(GO:0005522)
3.0	21.3	GO:0003680	AT DNA binding(GO:0003680)
3.0	12.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
3.0	21.1	GO:0019992	diacylglycerol binding(GO:0019992)
3.0	69.0	GO:0045499	chemorepellent activity(GO:0045499)
3.0	8.9	GO:0035939	microsatellite binding(GO:0035939)
2.9	23.4	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
2.8	11.3	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
2.7	8.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.7	8.0	GO:0018592	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
2.7	39.9	GO:0016805	dipeptidase activity(GO:0016805)
2.7	13.3	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
2.7	8.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
2.6	10.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.6	25.7	GO:0042577	lipid phosphatase activity(GO:0042577)
2.5	5.0	GO:0051425	PTB domain binding(GO:0051425)
2.5	22.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
2.4	12.1	GO:0048495	Roundabout binding(GO:0048495)
2.4	31.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
2.4	9.6	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
2.4	7.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.4	30.9	GO:0031005	filamin binding(GO:0031005)
2.4	4.7	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
2.3	25.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
2.3	2.3	GO:0038191	neuropilin binding(GO:0038191)
2.3	13.7	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
2.2	66.7	GO:0017147	Wnt-protein binding(GO:0017147)
2.2	8.8	GO:0097001	ceramide binding(GO:0097001)
2.2	8.7	GO:0004985	opioid receptor activity(GO:0004985)
2.1	6.4	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.1	8.4	GO:0071253	connexin binding(GO:0071253)
2.1	6.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
2.1	4.1	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
2.0	8.2	GO:0005042	netrin receptor activity(GO:0005042)
2.0	55.1	GO:0043015	gamma-tubulin binding(GO:0043015)
2.0	8.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
2.0	10.0	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
2.0	25.9	GO:0050811	GABA receptor binding(GO:0050811)
2.0	5.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
2.0	39.4	GO:0003785	actin monomer binding(GO:0003785)
2.0	7.9	GO:0046870	cadmium ion binding(GO:0046870)
1.9	13.5	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.9	7.7	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.9	68.0	GO:0015459	potassium channel regulator activity(GO:0015459)
1.8	16.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.8	7.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
1.8	9.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
1.8	8.9	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.8	7.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.8	5.3	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
1.7	7.0	GO:0015220	choline transmembrane transporter activity(GO:0015220)
1.7	25.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.7	5.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
1.7	6.8	GO:1904288	BAT3 complex binding(GO:1904288)
1.7	6.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
1.7	18.5	GO:0001223	transcription coactivator binding(GO:0001223)
1.7	25.2	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
1.7	14.9	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
1.6	6.5	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.6	6.5	GO:0008502	melatonin receptor activity(GO:0008502)
1.6	6.5	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
1.6	4.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
1.6	4.7	GO:0031708	endothelin B receptor binding(GO:0031708)
1.6	3.1	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
1.5	4.6	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
1.5	7.7	GO:0003708	retinoic acid receptor activity(GO:0003708)
1.5	1.5	GO:0072542	protein phosphatase activator activity(GO:0072542)
1.5	3.1	GO:0097016	L27 domain binding(GO:0097016)
1.5	4.5	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.5	25.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.5	33.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.5	17.5	GO:0031402	sodium ion binding(GO:0031402)
1.5	11.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
1.4	4.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.4	5.8	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
1.4	4.3	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
1.4	41.0	GO:0001540	beta-amyloid binding(GO:0001540)
1.4	36.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
1.4	36.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.3	1.3	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
1.3	5.4	GO:0015375	glycine:sodium symporter activity(GO:0015375)
1.3	6.7	GO:1990254	keratin filament binding(GO:1990254)
1.3	21.1	GO:0016917	GABA receptor activity(GO:0016917)
1.3	1.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
1.3	9.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
1.3	3.9	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
1.3	27.1	GO:0071837	HMG box domain binding(GO:0071837)
1.3	11.6	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
1.3	2.6	GO:0001030	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
1.3	15.3	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
1.3	19.1	GO:0030553	cGMP binding(GO:0030553)
1.3	3.8	GO:0034711	inhibin binding(GO:0034711)
1.3	23.8	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.3	3.8	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
1.3	22.5	GO:0017075	syntaxin-1 binding(GO:0017075)
1.2	8.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
1.2	3.7	GO:0005502	11-cis retinal binding(GO:0005502)
1.2	14.5	GO:0015026	coreceptor activity(GO:0015026)
1.2	6.0	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
1.2	7.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
1.2	3.6	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.2	3.5	GO:0055100	adiponectin binding(GO:0055100)
1.2	5.8	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.1	3.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
1.1	10.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
1.1	3.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
1.1	12.4	GO:0048018	receptor agonist activity(GO:0048018)
1.1	3.4	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.1	4.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
1.1	7.6	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
1.1	3.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.1	5.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.1	18.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
1.1	59.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.1	5.3	GO:0070051	fibrinogen binding(GO:0070051)
1.0	8.3	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.0	22.7	GO:0071855	neuropeptide receptor binding(GO:0071855)
1.0	2.1	GO:0042289	MHC class II protein binding(GO:0042289)
1.0	22.5	GO:0046875	ephrin receptor binding(GO:0046875)
1.0	11.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
1.0	4.1	GO:0098634	protein binding involved in cell-matrix adhesion(GO:0098634)
1.0	4.1	GO:0035184	histone threonine kinase activity(GO:0035184)
1.0	6.1	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.0	3.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.0	52.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
1.0	3.9	GO:0016018	cyclosporin A binding(GO:0016018)
1.0	4.8	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.0	15.3	GO:0008373	sialyltransferase activity(GO:0008373)
1.0	4.8	GO:0031628	opioid receptor binding(GO:0031628)
1.0	2.9	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.0	2.9	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.9	10.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.9	3.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.9	2.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.9	4.5	GO:0043208	glycosphingolipid binding(GO:0043208)
0.9	8.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.9	15.1	GO:0005112	Notch binding(GO:0005112)
0.9	3.5	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.9	7.0	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.9	2.6	GO:0004946	bombesin receptor activity(GO:0004946)
0.9	5.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.9	2.6	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.9	5.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.9	5.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.8	4.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.8	16.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.8	4.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.8	2.4	GO:0030957	Tat protein binding(GO:0030957)
0.8	12.5	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.8	10.8	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.8	3.8	GO:0071723	lipopeptide binding(GO:0071723)
0.7	2.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.7	2.1	GO:0008495	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.7	0.7	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.7	6.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7	1.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.7	2.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.7	16.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.7	2.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.7	6.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.7	2.1	GO:2001069	glycogen binding(GO:2001069)
0.7	3.5	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.7	2.0	GO:0070840	dynein complex binding(GO:0070840)
0.7	4.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7	2.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.7	1.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.6	14.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.6	3.9	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.6	2.6	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.6	7.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.6	1.9	GO:0050816	phosphothreonine binding(GO:0050816)
0.6	1.9	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.6	6.2	GO:0022821	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.6	7.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.6	11.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.6	4.3	GO:0005000	vasopressin receptor activity(GO:0005000)
0.6	0.6	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.6	7.7	GO:0008266	poly(U) RNA binding(GO:0008266)
0.6	6.3	GO:0004707	MAP kinase activity(GO:0004707)
0.6	10.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.6	4.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5	2.2	GO:0043842	Kdo transferase activity(GO:0043842)
0.5	1.6	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5	3.8	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5	2.1	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.5	1.6	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5	2.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.5	14.3	GO:0035254	glutamate receptor binding(GO:0035254)
0.5	4.7	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5	5.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.5	2.6	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.5	13.7	GO:0019894	kinesin binding(GO:0019894)
0.5	1.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.5	1.5	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.5	3.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.5	1.9	GO:0034584	piRNA binding(GO:0034584)
0.5	3.9	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.5	12.0	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.5	1.0	GO:0004359	glutaminase activity(GO:0004359)
0.5	5.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.5	1.4	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.5	1.4	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.5	1.9	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.5	4.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.5	1.4	GO:0016015	morphogen activity(GO:0016015)
0.5	3.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.4	1.8	GO:0004969	histamine receptor activity(GO:0004969)
0.4	4.3	GO:0031404	chloride ion binding(GO:0031404)
0.4	7.3	GO:0042923	neuropeptide binding(GO:0042923)
0.4	1.7	GO:0045545	syndecan binding(GO:0045545)
0.4	1.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4	1.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.4	20.4	GO:0008378	galactosyltransferase activity(GO:0008378)
0.4	2.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	1.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4	7.4	GO:0042056	chemoattractant activity(GO:0042056)
0.4	4.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	1.5	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.4	1.5	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.4	2.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4	3.2	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.3	2.8	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3	2.1	GO:0033691	sialic acid binding(GO:0033691)
0.3	31.4	GO:0008201	heparin binding(GO:0008201)
0.3	8.9	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.3	5.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.3	14.0	GO:0004027	alcohol sulfotransferase activity(GO:0004027)
0.3	6.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.3	0.7	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.3	6.7	GO:0030332	cyclin binding(GO:0030332)
0.3	4.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3	5.8	GO:0043014	alpha-tubulin binding(GO:0043014)
0.3	2.9	GO:0004000	adenosine deaminase activity(GO:0004000)
0.3	6.9	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.3	0.9	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.3	0.9	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3	2.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.3	1.8	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.3	2.9	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.3	10.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3	1.4	GO:0004565	beta-galactosidase activity(GO:0004565)
0.3	12.9	GO:0008907	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.3	0.3	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.3	1.1	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.3	1.6	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.3	4.3	GO:0016503	pheromone receptor activity(GO:0016503)
0.3	1.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.3	1.5	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	1.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	2.4	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2	2.4	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.2	0.5	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.2	5.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.2	2.8	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.2	0.9	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.2	7.0	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.2	0.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.2	1.3	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
0.2	0.9	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.2	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	1.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.2	3.1	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.2	4.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	1.0	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.2	1.7	GO:0016783	sulfurtransferase activity(GO:0016783)
0.2	2.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2	1.8	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	0.9	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.2	0.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	0.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.2	0.3	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.2	3.1	GO:0070888	E-box binding(GO:0070888)
0.2	0.3	GO:0042895	antibiotic transporter activity(GO:0042895)
0.2	0.6	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.2	0.5	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2	0.2	GO:0030172	troponin C binding(GO:0030172)
0.2	0.5	GO:0004096	catalase activity(GO:0004096)
0.2	0.5	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	1.4	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.9	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.3	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	26.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1	0.4	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.1	GO:0051378	serotonin binding(GO:0051378)
0.1	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.1	0.5	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.1	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1	1.3	GO:0030552	cAMP binding(GO:0030552)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.1	0.2	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.8	GO:0055103	ligase regulator activity(GO:0055103)
0.1	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.1	0.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	2.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	1.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.0	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	7.4	GO:0005549	odorant binding(GO:0005549)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	63.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
2.3	74.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
2.2	28.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
2.1	62.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
1.7	40.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.5	24.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.5	51.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.4	24.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
1.4	29.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.3	21.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.3	7.6	ST G ALPHA I PATHWAY	G alpha i Pathway
1.1	27.2	PID EPHA FWDPATHWAY	EPHA forward signaling
1.1	35.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.0	20.5	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.9	18.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.8	0.8	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.8	7.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.8	12.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.8	2.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.8	8.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.6	11.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.6	1.3	PID REELIN PATHWAY	Reelin signaling pathway
0.6	0.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.6	0.6	PID S1P S1P1 PATHWAY	S1P1 pathway
0.5	2.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.5	1.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.4	6.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.4	1.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	9.8	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.4	2.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.4	3.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	4.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	4.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	0.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.3	1.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	8.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	1.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	0.8	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	4.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	2.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	6.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	18.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	6.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	1.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	0.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.1	0.5	PID ALK2 PATHWAY	ALK2 signaling events
0.1	3.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	17.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.9	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.9	139.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
6.4	12.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
5.6	5.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
4.2	46.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
3.5	3.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
3.4	72.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
3.4	64.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.6	18.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
2.6	25.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
2.5	42.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.5	47.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
2.5	2.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
2.5	4.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
2.3	9.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
2.3	18.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
2.1	24.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
2.0	22.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
2.0	17.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.9	48.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.8	24.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.8	20.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
1.8	41.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.7	20.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.6	8.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.6	33.0	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
1.5	62.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
1.5	1.5	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
1.5	20.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
1.5	4.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.4	11.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.4	31.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
1.3	2.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
1.3	3.9	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
1.2	9.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.2	8.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
1.1	3.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.1	17.7	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
1.1	24.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
1.1	27.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.1	11.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
1.0	15.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
1.0	22.6	REACTOME KINESINS	Genes involved in Kinesins
1.0	16.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
1.0	12.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.0	1.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
1.0	8.8	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
1.0	11.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.0	7.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.9	8.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.9	8.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.9	14.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.8	24.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.8	7.0	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.7	5.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.7	11.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.7	3.5	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.7	11.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.7	13.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6	5.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.6	0.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.6	7.1	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6	1.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.6	6.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.6	23.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6	19.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.6	20.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.5	10.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.5	6.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.5	17.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.5	6.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	22.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.4	0.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4	9.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4	3.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.4	0.7	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.3	0.6	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3	5.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.3	2.9	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3	1.8	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	2.0	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	2.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	1.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	1.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	1.8	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.2	1.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	6.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	2.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	3.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.2	1.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	2.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	3.7	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.1	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.1	4.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	0.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Results for Sox2

Z-value: 5.84

Motif logo

Transcription factors associated with Sox2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox2 motif across conditions

Conditions sorted by the z-value of the Sox2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: