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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Sox5_Sry

Z-value: 0.95

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Transcription factors associated with Sox5_Sry

Gene Symbol	Gene ID	Gene Info
Sox5 Ensembl NCBI MGI UniProt	ENSMUSG00000041540.10	SRY (sex determining region Y)-box 5
Sry Ensembl NCBI MGI UniProt	ENSMUSG00000069036.3	sex determining region of Chr Y

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_143941281_143941747	Sox5	5574	0.279825	-0.71	1.3e-09	Click!
chr6_144251334_144251522	Sox5	41860	0.208507	-0.67	1.8e-08	Click!
chr6_144209964_144210660	Sox5	744	0.796140	-0.65	6.9e-08	Click!
chr6_144251546_144251744	Sox5	42077	0.207798	-0.65	8.4e-08	Click!
chr6_144251849_144252061	Sox5	42387	0.206787	-0.64	1.4e-07	Click!

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_178471923_178472101	2.26	Cdh26	cadherin-like 26	11382	0.22
chr10_60351822_60352131	2.26	Vsir	V-set immunoregulatory receptor	2653	0.28
chr11_69062573_69063351	1.84	9330160F10Rik	RIKEN cDNA 9330160F10 gene	2479	0.1
chr4_130715764_130715925	1.74	Snord85	small nucleolar RNA, C/D box 85	33790	0.11
chr2_28598572_28599148	1.67	Gm22675	predicted gene, 22675	3733	0.13
chr4_150890043_150890216	1.66	Park7	Parkinson disease (autosomal recessive, early onset) 7	11706	0.14
chr1_193156667_193156839	1.63	Irf6	interferon regulatory factor 6	84	0.95
chr5_130200680_130200989	1.59	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	6219	0.1
chr12_112585016_112585203	1.55	Inf2	inverted formin, FH2 and WH2 domain containing	3675	0.18
chr7_35350340_35350583	1.52	Rhpn2	rhophilin, Rho GTPase binding protein 2	16131	0.13
chr17_86313458_86313775	1.48	2010106C02Rik	RIKEN cDNA 2010106C02 gene	26438	0.23
chr2_22587496_22588353	1.47	Gm13341	predicted gene 13341	38	0.95
chr3_94783418_94783615	1.47	Cgn	cingulin	2935	0.17
chr12_76558245_76558525	1.46	Plekhg3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	3853	0.17
chr15_96455910_96456125	1.44	Scaf11	SR-related CTD-associated factor 11	4783	0.23
chr7_16792307_16792658	1.43	Slc1a5	solute carrier family 1 (neutral amino acid transporter), member 5	545	0.64
chr1_179854274_179854595	1.35	Ahctf1	AT hook containing transcription factor 1	50754	0.12
chr3_121346684_121346842	1.34	Gm5711	predicted gene 5711	33916	0.12
chr3_136610301_136610480	1.33	Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	59734	0.13
chr16_32563013_32563416	1.32	Gm34680	predicted gene, 34680	11472	0.14
chr4_115514141_115514292	1.31	Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	4048	0.14
chr1_167802317_167803268	1.30	Lmx1a	LIM homeobox transcription factor 1 alpha	113235	0.07
chr7_123430155_123430354	1.29	Lcmt1	leucine carboxyl methyltransferase 1	2394	0.29
chr4_59292306_59292644	1.29	Susd1	sushi domain containing 1	23491	0.17
chr2_171633456_171634007	1.28	Gm26489	predicted gene, 26489	327300	0.01
chr5_144317459_144317816	1.26	Baiap2l1	BAI1-associated protein 2-like 1	28730	0.12
chr2_103466992_103467253	1.26	Cat	catalase	18003	0.16
chr11_57998862_57999212	1.24	Larp1	La ribonucleoprotein domain family, member 1	10027	0.15
chr10_80435784_80436272	1.23	Tcf3	transcription factor 3	2381	0.14
chr1_24615430_24615609	1.22	Gm28661	predicted gene 28661	46	0.86
chr6_14185920_14186504	1.20	Gm23760	predicted gene, 23760	72896	0.11
chr2_132846257_132847404	1.20	Crls1	cardiolipin synthase 1	142	0.79
chr4_141131586_141132124	1.19	Szrd1	SUZ RNA binding domain containing 1	7872	0.11
chr1_88044901_88045120	1.19	AC087801.1	UDP glycosyltransferase 1 family (Ytg1) pseudogene	7410	0.08
chr13_41403888_41404241	1.19	Gm48570	predicted gene, 48570	1773	0.3
chr3_148422779_148423056	1.18	Gm43576	predicted gene 43576	32024	0.22
chr18_64182836_64182987	1.18	St8sia3os	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand	14107	0.15
chr8_33987076_33987405	1.16	Gm45817	predicted gene 45817	40	0.96
chr2_163586914_163587109	1.16	Ttpal	tocopherol (alpha) transfer protein-like	15303	0.13
chr12_84084567_84084718	1.15	Gm8385	predicted gene 8385	2999	0.12
chr10_123048822_123048979	1.14	Mon2	MON2 homolog, regulator of endosome to Golgi trafficking	15769	0.19
chr14_31433815_31434149	1.14	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	2083	0.25
chr5_32132959_32134082	1.13	Gm10463	predicted gene 10463	349	0.83
chr2_14176921_14177097	1.13	Tmem236	transmembrane protein 236	2486	0.22
chr10_26828769_26829098	1.13	Arhgap18	Rho GTPase activating protein 18	6331	0.25
chr7_100590312_100590463	1.12	Mrpl48	mitochondrial ribosomal protein L48	1039	0.35
chr16_95926674_95926827	1.12	1600002D24Rik	RIKEN cDNA 1600002D24 gene	2327	0.28
chr5_73313719_73313877	1.09	Gm42732	predicted gene 42732	2434	0.16
chr11_94365445_94365605	1.09	Abcc3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	2398	0.24
chr12_91849475_91849887	1.07	Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	524	0.73
chr4_128805691_128806359	1.05	Zfp362	zinc finger protein 362	20	0.97
chr3_89998220_89998476	1.05	Hax1	HCLS1 associated X-1	14	0.85
chr19_58050434_58050717	1.04	Mir5623	microRNA 5623	592	0.82
chr11_58021710_58021982	1.04	Larp1	La ribonucleoprotein domain family, member 1	12782	0.15
chr1_172903375_172903674	1.04	Apcs	serum amyloid P-component	8483	0.16
chr1_155030934_155031254	1.04	Gm29441	predicted gene 29441	645	0.72
chr10_93143358_93143676	1.03	Cdk17	cyclin-dependent kinase 17	17358	0.17
chr11_54804054_54804205	1.03	Lyrm7os	LYR motif containing 7, opposite strand	15790	0.12
chr1_72255145_72255783	1.02	Gm25939	predicted gene, 25939	456	0.72
chr7_123420015_123420410	1.01	Lcmt1	leucine carboxyl methyltransferase 1	2069	0.31
chr8_122742393_122743116	1.01	C230057M02Rik	RIKEN cDNA C230057M02 gene	4243	0.12
chr3_103801587_103801856	1.00	Gm15471	predicted gene 15471	1408	0.2
chr7_45097569_45097720	0.99	Rcn3	reticulocalbin 3, EF-hand calcium binding domain	5423	0.05
chr5_109844725_109844919	0.98	Gm10416	predicted pseudogene 10416	10677	0.17
chr5_22348847_22349031	0.98	Reln	reelin	4237	0.17
chr19_29066936_29067376	0.98	Gm9895	predicted gene 9895	191	0.91
chr7_134690071_134690222	0.98	Dock1	dedicator of cytokinesis 1	19024	0.22
chr3_148420483_148420859	0.97	Gm43576	predicted gene 43576	34270	0.21
chr17_34118027_34118475	0.97	Brd2	bromodomain containing 2	238	0.72
chr16_45644024_45644312	0.96	Gm49585	predicted gene, 49585	1811	0.28
chr14_64689914_64690065	0.96	Kif13b	kinesin family member 13B	37387	0.15
chr7_132308529_132308892	0.95	Gm44891	predicted gene 44891	5368	0.15
chr10_96235024_96235388	0.95	4930459C07Rik	RIKEN cDNA 4930459C07 gene	8999	0.2
chr2_68934625_68935021	0.94	Cers6	ceramide synthase 6	12437	0.14
chr3_137941200_137941383	0.94	Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	13422	0.1
chr4_150493335_150493527	0.94	Rere	arginine glutamic acid dipeptide (RE) repeats	5038	0.27
chr4_132863078_132863284	0.94	Stx12	syntaxin 12	79	0.95
chr6_13052400_13052710	0.93	Gm5300	predicted gene 5300	4042	0.25
chr19_3995581_3995732	0.93	Tbx10	T-box 10	2904	0.08
chr17_59012796_59013456	0.92	Nudt12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	142	0.96
chr6_134678296_134678471	0.92	Gm44017	predicted gene, 44017	11476	0.14
chr5_125406078_125406690	0.92	Dhx37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	9513	0.11
chr1_74027469_74027800	0.92	Tns1	tensin 1	9499	0.23
chr12_84963175_84963419	0.92	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	2733	0.18
chr11_79229715_79229866	0.91	Wsb1	WD repeat and SOCS box-containing 1	13159	0.16
chr19_46532071_46532499	0.91	Arl3	ADP-ribosylation factor-like 3	10528	0.14
chr19_58043550_58043869	0.91	Mir5623	microRNA 5623	7458	0.28
chr17_43504311_43504617	0.90	Mep1a	meprin 1 alpha	1652	0.36
chr12_84202046_84202444	0.90	Gm31513	predicted gene, 31513	6276	0.11
chr16_47171563_47171714	0.90	Gm18169	predicted gene, 18169	40732	0.21
chr4_138065957_138066120	0.90	Eif4g3	eukaryotic translation initiation factor 4 gamma, 3	61286	0.1
chr6_5156932_5157313	0.90	Pon1	paraoxonase 1	36641	0.14
chr2_91537896_91538139	0.89	Ckap5	cytoskeleton associated protein 5	8303	0.15
chr1_67116639_67117125	0.89	Cps1	carbamoyl-phosphate synthetase 1	6144	0.25
chr15_79323845_79324092	0.89	Pla2g6	phospholipase A2, group VI	402	0.74
chr11_75948882_75949196	0.89	Rph3al	rabphilin 3A-like (without C2 domains)	10610	0.2
chr7_128460110_128460271	0.89	Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	1019	0.35
chr16_32008367_32008518	0.88	Senp5	SUMO/sentrin specific peptidase 5	5155	0.1
chr7_81739113_81739266	0.87	Gm18806	predicted gene, 18806	3156	0.16
chr17_24848922_24849092	0.87	Fahd1	fumarylacetoacetate hydrolase domain containing 1	1357	0.2
chr5_66073877_66074050	0.87	Gm43775	predicted gene 43775	1068	0.4
chr14_79451589_79452546	0.87	Kbtbd6	kelch repeat and BTB (POZ) domain containing 6	232	0.9
chr9_99098900_99099051	0.86	Pik3cb	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	40950	0.12
chr13_90799208_90799500	0.86	Gm47521	predicted gene, 47521	21271	0.19
chr6_143154565_143154716	0.86	Gm31108	predicted gene, 31108	709	0.61
chr9_108338578_108339700	0.86	Gpx1	glutathione peroxidase 1	85	0.89
chr11_69967024_69967389	0.86	Cldn7	claudin 7	288	0.7
chr5_67572619_67572866	0.86	1700025A08Rik	RIKEN cDNA 1700025A08 gene	35084	0.11
chr8_120543978_120544129	0.85	Mir7687	microRNA 7687	5357	0.12
chr1_88049227_88049378	0.85	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	6086	0.08
chr3_122814605_122814890	0.84	4930447N08Rik	RIKEN cDNA 4930447N08 gene	12699	0.14
chr18_8644320_8645204	0.84	Gm35232	predicted gene, 35232	34289	0.18
chr5_139384476_139384627	0.84	Gpr146	G protein-coupled receptor 146	3970	0.13
chr7_70515380_70515786	0.83	Gm44811	predicted gene 44811	15639	0.13
chr19_17328336_17328491	0.83	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	7023	0.23
chr3_10136204_10136355	0.82	Gm37308	predicted gene, 37308	46324	0.08
chr9_70848458_70848648	0.82	Gm3436	predicted pseudogene 3436	4023	0.25
chr5_147894219_147894411	0.82	Slc46a3	solute carrier family 46, member 3	500	0.77
chr16_87366227_87366378	0.82	N6amt1	N-6 adenine-specific DNA methyltransferase 1 (putative)	12057	0.19
chr4_117682587_117682738	0.81	Dmap1	DNA methyltransferase 1-associated protein 1	389	0.81
chr7_97790389_97790572	0.81	Pak1	p21 (RAC1) activated kinase 1	1939	0.34
chr7_143500903_143501124	0.81	Phlda2	pleckstrin homology like domain, family A, member 2	1528	0.26
chr5_86173166_86173471	0.81	Uba6	ubiquitin-like modifier activating enzyme 6	515	0.78
chr10_21612801_21612952	0.80	1700020N01Rik	RIKEN cDNA 1700020N01 gene	3444	0.3
chr11_12036502_12038049	0.80	Grb10	growth factor receptor bound protein 10	126	0.97
chr16_58519486_58519656	0.80	St3gal6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3773	0.22
chr10_51453996_51454265	0.80	Gm46189	predicted gene, 46189	1850	0.26
chr3_60094748_60095038	0.80	Sucnr1	succinate receptor 1	12991	0.19
chr11_113223856_113224035	0.80	4732490B19Rik	RIKEN cDNA 4732490B19 gene	14276	0.24
chr1_170479226_170479433	0.80	Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	24415	0.21
chr5_148789072_148789662	0.79	4930505K14Rik	RIKEN cDNA 4930505K14 gene	11404	0.15
chr7_4806720_4807013	0.79	Ube2s	ubiquitin-conjugating enzyme E2S	4253	0.09
chr13_93192635_93192963	0.79	Tent2	terminal nucleotidyltransferase 2	414	0.86
chr18_23815450_23815627	0.79	Gm23207	predicted gene, 23207	1833	0.32
chr4_137772776_137772971	0.78	Alpl	alkaline phosphatase, liver/bone/kidney	3053	0.26
chr5_114551218_114551384	0.78	Gm13790	predicted gene 13790	12	0.97
chr13_112833681_112833853	0.78	Plpp1	phospholipid phosphatase 1	32904	0.12
chr10_41205379_41205541	0.78	Gm25526	predicted gene, 25526	10585	0.2
chr11_69073513_69073915	0.78	Snord118	small nucleolar RNA, C/D box 118	287	0.63
chr15_103479382_103479548	0.78	Nckap1l	NCK associated protein 1 like	317	0.85
chr17_31079187_31079338	0.77	Gm25447	predicted gene, 25447	19658	0.12
chr6_72396903_72397079	0.77	Vamp8	vesicle-associated membrane protein 8	6288	0.1
chr10_39907400_39907573	0.77	Gm8911	predicted gene 8911	3663	0.13
chr5_151165148_151165337	0.77	Stard13	StAR-related lipid transfer (START) domain containing 13	24908	0.21
chr1_167354724_167354875	0.77	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	4487	0.14
chr5_4019546_4019718	0.77	Akap9	A kinase (PRKA) anchor protein (yotiao) 9	3783	0.23
chr14_98084865_98085016	0.77	Gm16331	predicted gene 16331	33569	0.21
chr16_77027071_77027249	0.77	Usp25	ubiquitin specific peptidase 25	13373	0.21
chr2_133455802_133456121	0.77	Gm14100	predicted gene 14100	7157	0.23
chr8_66363123_66363725	0.77	Marchf1	membrane associated ring-CH-type finger 1	22870	0.19
chr3_117873618_117873778	0.76	Snx7	sorting nexin 7	4762	0.22
chr15_77882572_77883557	0.76	Txn2	thioredoxin 2	32636	0.11
chr2_103749241_103749406	0.76	Nat10	N-acetyltransferase 10	5966	0.14
chr4_132484893_132485044	0.76	Med18	mediator complex subunit 18	21047	0.08
chr9_31851792_31852171	0.75	Gm31497	predicted gene, 31497	54012	0.11
chr13_77548432_77549057	0.75	Gm9634	predicted gene 9634	5629	0.31
chr17_46735053_46735204	0.75	Cnpy3	canopy FGF signaling regulator 3	2499	0.14
chr12_55054945_55055220	0.74	2700097O09Rik	RIKEN cDNA 2700097O09 gene	981	0.4
chr17_31474444_31474595	0.74	Pde9a	phosphodiesterase 9A	3467	0.12
chr9_61120633_61120784	0.74	Gm33914	predicted gene, 33914	6323	0.15
chr11_50292225_50292589	0.74	Maml1	mastermind like transcriptional coactivator 1	96	0.95
chr4_98318734_98319169	0.73	0610025J13Rik	RIKEN cDNA 0610025J13 gene	2447	0.26
chr5_123014528_123014681	0.73	Orai1	ORAI calcium release-activated calcium modulator 1	470	0.39
chr6_129212899_129213056	0.73	2310001H17Rik	RIKEN cDNA 2310001H17 gene	20997	0.1
chr1_128608127_128608278	0.73	Cxcr4	chemokine (C-X-C motif) receptor 4	15909	0.21
chr6_31148348_31148689	0.73	Gm37728	predicted gene, 37728	1099	0.4
chr10_18371017_18371277	0.73	Nhsl1	NHS-like 1	19175	0.19
chr12_39885382_39885668	0.73	Gm4263	predicted gene 4263	10075	0.21
chr15_99130441_99130592	0.72	Gm25183	predicted gene, 25183	2656	0.15
chr17_64609838_64610010	0.72	Man2a1	mannosidase 2, alpha 1	9188	0.26
chr11_29514525_29514826	0.72	Prorsd1	prolyl-tRNA synthetase domain containing 1	356	0.49
chr19_47461497_47461648	0.72	Sh3pxd2a	SH3 and PX domains 2A	2675	0.27
chr8_107109103_107109254	0.71	C630050I24Rik	RIKEN cDNA C630050I24 gene	9932	0.11
chr11_96397203_96397354	0.71	Gm11531	predicted gene 11531	5166	0.12
chr7_132772857_132773208	0.71	Fam53b	family with sequence similarity 53, member B	3884	0.24
chr19_36793588_36793739	0.71	Gm50112	predicted gene, 50112	24985	0.17
chr11_108309813_108310102	0.71	Apoh	apolipoprotein H	33397	0.16
chr17_47428847_47429237	0.71	Gm50461	predicted gene, 50461	7162	0.11
chr6_40635278_40635429	0.71	Mgam	maltase-glucoamylase	6522	0.16
chr12_108857921_108858072	0.71	Gm22079	predicted gene, 22079	4673	0.11
chr18_79781586_79781737	0.71	Gm19062	predicted gene, 19062	80238	0.07
chr5_139101902_139102053	0.71	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	10667	0.18
chr7_29180085_29180886	0.71	Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	4	0.94
chr16_91292688_91293239	0.71	Olig1	oligodendrocyte transcription factor 1	23191	0.11
chr7_108933988_108934499	0.71	Eif3f	eukaryotic translation initiation factor 3, subunit F	174	0.91
chr5_52782674_52783192	0.71	Zcchc4	zinc finger, CCHC domain containing 4	121	0.97
chr5_100368601_100368752	0.71	Sec31a	Sec31 homolog A (S. cerevisiae)	4406	0.19
chr6_29267024_29267197	0.71	Hilpda	hypoxia inducible lipid droplet associated	5378	0.13
chr13_43525454_43525719	0.71	Gm32939	predicted gene, 32939	4634	0.16
chr6_129513372_129513692	0.70	Tmem52b	transmembrane protein 52B	919	0.35
chr11_53424916_53425067	0.70	Leap2	liver-expressed antimicrobial peptide 2	1821	0.16
chr4_144895166_144895503	0.70	Dhrs3	dehydrogenase/reductase (SDR family) member 3	2115	0.35
chr13_43236620_43236988	0.70	Tbc1d7	TBC1 domain family, member 7	65303	0.1
chr4_151044619_151045451	0.70	Per3	period circadian clock 3	370	0.84
chr2_6129008_6129159	0.70	Proser2	proline and serine rich 2	1056	0.45
chr15_58743876_58744227	0.70	Gm20712	predicted gene 20712	37900	0.14
chr6_145761297_145761448	0.69	Rassf8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	10801	0.2
chr6_125342392_125342543	0.69	Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	6895	0.12
chr11_97241392_97241543	0.69	Npepps	aminopeptidase puromycin sensitive	399	0.8
chr2_173026305_173026589	0.69	Rbm38	RNA binding motif protein 38	3397	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0006742	NADP catabolic process(GO:0006742)
0.3	1.6	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.3	0.8	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	0.7	GO:0003162	atrioventricular node development(GO:0003162)
0.2	0.7	GO:0006481	C-terminal protein methylation(GO:0006481)
0.2	0.6	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.2	1.0	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.2	0.9	GO:0021764	amygdala development(GO:0021764)
0.2	1.2	GO:0015825	L-serine transport(GO:0015825)
0.2	0.5	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2	0.7	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1	0.4	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1	0.5	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.4	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.1	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.5	GO:0051031	tRNA transport(GO:0051031)
0.1	0.5	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.6	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	0.4	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.7	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	0.3	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	0.6	GO:0048539	bone marrow development(GO:0048539)
0.1	1.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.5	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.3	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.4	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.3	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	0.3	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.1	0.2	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.1	0.2	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1	0.2	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.1	0.2	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.3	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.3	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1	0.2	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.1	0.6	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.2	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1	0.2	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.8	GO:0043248	proteasome assembly(GO:0043248)
0.1	0.2	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.1	0.2	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.1	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.1	0.2	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	0.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.2	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.1	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.1	0.2	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.1	0.1	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.1	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.6	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	0.2	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.1	0.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.3	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0043308	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0	0.4	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0031627	telomeric loop formation(GO:0031627)
0.0	0.3	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.0	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0097503	sialylation(GO:0097503)
0.0	0.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.3	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0036492	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.0	0.2	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.2	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.2	GO:0043328	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.2	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0	0.2	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	1.4	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.3	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.2	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.4	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	1.3	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.1	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.0	0.8	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0072040	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.4	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.5	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.2	GO:0060352	cell adhesion molecule production(GO:0060352)
0.0	0.2	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.2	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.0	0.7	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.2	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.1	GO:1903659	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.0	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.0	0.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.4	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.2	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.8	GO:0045187	regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.1	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.1	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.1	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.4	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.3	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.6	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.1	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.1	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.3	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.5	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.3	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0	0.1	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	0.1	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.0	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.0	0.1	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0	0.3	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.0	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.0	0.1	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.4	GO:0010922	positive regulation of phosphatase activity(GO:0010922)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0000237	leptotene(GO:0000237)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.0	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.2	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.1	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0	0.0	GO:0051464	positive regulation of cortisol secretion(GO:0051464)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.2	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.3	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.3	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.7	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.2	GO:1903393	positive regulation of adherens junction organization(GO:1903393)
0.0	0.0	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.0	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.2	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.2	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.2	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.2	GO:0031280	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0	0.0	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.1	GO:2001271	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.5	GO:0000578	embryonic axis specification(GO:0000578)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0010896	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.7	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.1	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.0	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.4	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:2000409	regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
0.0	0.1	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.0	GO:0044793	negative regulation by host of viral process(GO:0044793)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.0	GO:0007619	courtship behavior(GO:0007619)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0072103	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0	0.1	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.3	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
0.0	0.2	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.0	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0	0.0	GO:0061450	trophoblast cell migration(GO:0061450)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.3	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.4	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.0	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370)
0.0	0.0	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.0	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0033136	serine phosphorylation of STAT3 protein(GO:0033136)
0.0	0.2	GO:0070873	regulation of glycogen metabolic process(GO:0070873)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.1	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.0	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.0	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.0	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0	0.0	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.2	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.0	GO:0002835	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.0	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.0	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.0	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0071801	regulation of podosome assembly(GO:0071801)
0.0	0.0	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0060214	endocardium formation(GO:0060214)
0.0	0.0	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0097413	Lewy body(GO:0097413)
0.2	0.7	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.7	GO:0031209	SCAR complex(GO:0031209)
0.1	0.6	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.2	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	0.8	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.1	0.4	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.9	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.2	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.1	0.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0000814	ESCRT II complex(GO:0000814)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.1	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.3	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0071953	elastic fiber(GO:0071953)
0.0	0.8	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	1.1	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.4	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.3	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.1	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	1.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.0	GO:0005818	aster(GO:0005818)
0.0	0.2	GO:0031970	nuclear envelope lumen(GO:0005641) organelle envelope lumen(GO:0031970)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	1.1	GO:0070469	respiratory chain(GO:0070469)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.8	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	2.0	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.0	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	1.0	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.0	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.2	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.7	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.5	GO:0016459	myosin complex(GO:0016459)
0.0	0.0	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.2	0.9	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.6	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.7	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.9	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.5	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.9	GO:0008430	selenium binding(GO:0008430)
0.1	0.6	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.1	0.3	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.4	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.4	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.5	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.2	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.3	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.3	GO:0042731	PH domain binding(GO:0042731)
0.1	0.2	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.2	GO:1990188	euchromatin binding(GO:1990188)
0.1	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.2	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	0.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.4	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.3	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.4	GO:0070251	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.7	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0043842	Kdo transferase activity(GO:0043842)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0018585	fluorene oxygenase activity(GO:0018585)
0.0	0.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0016749	N-succinyltransferase activity(GO:0016749)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.7	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.4	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.5	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.9	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	1.4	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.5	GO:0043849	Ras palmitoyltransferase activity(GO:0043849)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.0	GO:0036403	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.5	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.9	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.7	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	1.3	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.0	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0034843	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	1.1	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.0	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.0	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.0	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.2	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.0	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.0	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	1.8	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.5	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.8	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.7	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.1	1.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.6	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	2.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.0	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	1.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.4	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Results for Sox5_Sry

Z-value: 0.95

Motif logo

Transcription factors associated with Sox5_Sry

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: