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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Sp1

Z-value: 4.24

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Transcription factors associated with Sp1

Gene Symbol	Gene ID	Gene Info
Sp1 Ensembl NCBI MGI UniProt	ENSMUSG00000001280.6	trans-acting transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_102406111_102406291	Sp1	58	0.946722	0.65	7.1e-08	Click!
chr15_102406566_102406757	Sp1	94	0.936294	0.62	4.0e-07	Click!
chr15_102406310_102406535	Sp1	42	0.949856	0.62	4.6e-07	Click!
chr15_102405863_102406047	Sp1	188	0.888861	0.60	1.3e-06	Click!
chr15_102405584_102405798	Sp1	452	0.678928	0.60	1.6e-06	Click!

Activity of the Sp1 motif across conditions

Conditions sorted by the z-value of the Sp1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_24259035_24259422	44.44	Gm7701	predicted gene 7701	1850	0.37
chr14_48475621_48476075	43.94	Tmem260	transmembrane protein 260	3526	0.2
chr15_98608664_98610204	39.21	Adcy6	adenylate cyclase 6	598	0.55
chr4_140701770_140702866	38.17	Rcc2	regulator of chromosome condensation 2	845	0.47
chr1_33600072_33600973	35.79	Gm37618	predicted gene, 37618	16310	0.15
chrX_142680720_142682167	35.65	Tmem164	transmembrane protein 164	25	0.98
chr3_52985507_52985880	35.48	Cog6	component of oligomeric golgi complex 6	8992	0.16
chr2_174329445_174331091	33.88	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	19	0.97
chr14_20793233_20794132	33.12	Camk2g	calcium/calmodulin-dependent protein kinase II gamma	284	0.68
chr6_125095392_125097556	31.54	Chd4	chromodomain helicase DNA binding protein 4	95	0.84
chr17_34898151_34899707	30.44	Ehmt2	euchromatic histone lysine N-methyltransferase 2	25	0.87
chr9_65826224_65827697	29.55	Zfp609	zinc finger protein 609	604	0.65
chr5_109557850_109558797	29.52	Crlf2	cytokine receptor-like factor 2	613	0.67
chr7_25249061_25250506	29.06	Erf	Ets2 repressor factor	947	0.33
chr7_28179836_28180482	28.72	Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	107	0.93
chr17_30004516_30005139	27.32	Zfand3	zinc finger, AN1-type domain 3	94	0.55
chr2_153492229_153493481	27.26	4930404H24Rik	RIKEN cDNA 4930404H24 gene	65	0.82
chr2_48949106_48950119	26.79	Mbd5	methyl-CpG binding domain protein 5	89	0.8
chr5_137786077_137787112	26.47	Mepce	methylphosphate capping enzyme	69	0.92
chr6_97204968_97206158	26.37	Uba3	ubiquitin-like modifier activating enzyme 3	2	0.97
chr2_75703696_75705127	25.06	Nfe2l2	nuclear factor, erythroid derived 2, like 2	78	0.81
chr15_79690079_79691459	24.81	Gtpbp1	GTP binding protein 1	76	0.92
chr7_133710663_133710880	24.72	Uros	uroporphyrinogen III synthase	699	0.49
chr11_69996486_69997590	24.63	Phf23	PHD finger protein 23	47	0.91
chr17_45685681_45686990	24.55	Mrpl14	mitochondrial ribosomal protein L14	13	0.54
chr6_120665862_120666733	24.49	Cecr2	CECR2, histone acetyl-lysine reader	72	0.98
chr14_62760761_62761843	23.68	Ints6	integrator complex subunit 6	133	0.95
chr2_170130477_170131578	23.65	Zfp217	zinc finger protein 217	193	0.97
chr9_109094576_109096217	23.47	Plxnb1	plexin B1	7	0.95
chr7_25686729_25687529	23.38	Tgfb1	transforming growth factor, beta 1	127	0.91
chr5_22344110_22345571	23.25	Reln	reelin	138	0.95
chr11_102316544_102317735	23.22	Ubtf	upstream binding transcription factor, RNA polymerase I	148	0.92
chr7_127026546_127028177	23.18	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	324	0.58
chr3_51340298_51341882	22.94	Elf2	E74-like factor 2	427	0.74
chr11_74831594_74833056	22.53	Mnt	max binding protein	1405	0.31
chr10_69910043_69910940	22.52	Ank3	ankyrin 3, epithelial	4374	0.35
chr10_80150235_80151164	22.39	Midn	midnolin	242	0.82
chr11_98766610_98767640	22.23	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3301	0.13
chr15_102470670_102471447	22.22	Pcbp2	poly(rC) binding protein 2	10	0.95
chr2_51946774_51947120	22.21	Nmi	N-myc (and STAT) interactor	5630	0.18
chr4_156197393_156197799	22.08	Agrn	agrin	108	0.92
chr19_41482494_41483686	21.96	Lcor	ligand dependent nuclear receptor corepressor	61	0.98
chr7_133710460_133710636	21.26	Uros	uroporphyrinogen III synthase	476	0.63
chr11_74837693_74838808	21.22	Mnt	max binding protein	782	0.52
chr10_127508848_127510720	21.16	Stac3	SH3 and cysteine rich domain 3	2559	0.15
chr5_140829777_140830873	20.76	Gna12	guanine nucleotide binding protein, alpha 12	106	0.97
chr18_21299601_21300892	20.63	Garem1	GRB2 associated regulator of MAPK1 subtype 1	108	0.96
chr7_127768560_127769629	20.31	Orai3	ORAI calcium release-activated calcium modulator 3	721	0.4
chr8_107030704_107031406	20.24	Gm16208	predicted gene 16208	133	0.53
chrX_48284788_48285532	20.04	Gm22528	predicted gene, 22528	14419	0.13
chr6_72097140_72098281	19.95	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	47	0.96
chr8_120486990_120488549	19.87	Gse1	genetic suppressor element 1, coiled-coil protein	678	0.64
chr4_129188973_129189769	19.81	S100pbp	S100P binding protein	127	0.78
chr10_80576603_80578409	19.70	Klf16	Kruppel-like factor 16	185	0.86
chr11_70021148_70021981	19.68	Dlg4	discs large MAGUK scaffold protein 4	2356	0.11
chrX_42067696_42069057	19.67	Xiap	X-linked inhibitor of apoptosis	22	0.98
chr7_118243052_118244285	19.51	Smg1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	2	0.72
chr11_77607040_77608322	19.30	Taok1	TAO kinase 1	134	0.94
chr13_45389281_45390472	19.24	Mylip	myosin regulatory light chain interacting protein	134	0.97
chrX_51204673_51205680	19.13	Mbnl3	muscleblind like splicing factor 3	656	0.65
chr5_149229091_149229712	18.80	2310047D07Rik	RIKEN cDNA 2310047D07 gene	1931	0.18
chr3_100488535_100489982	18.76	Tent5c	terminal nucleotidyltransferase 5C	60	0.85
chrX_169997850_169998483	18.69	Gm15247	predicted gene 15247	11227	0.14
chr2_153528510_153529333	18.67	Nol4l	nucleolar protein 4-like	1050	0.54
chr11_98741567_98742727	18.60	Thra	thyroid hormone receptor alpha	11	0.95
chr1_134559997_134561478	18.60	Kdm5b	lysine (K)-specific demethylase 5B	530	0.69
chr9_61370339_61371660	18.58	Gm10655	predicted gene 10655	628	0.63
chr1_166002288_166003185	18.56	Pou2f1	POU domain, class 2, transcription factor 1	58	0.72
chr15_100599610_100600576	18.44	Pou6f1	POU domain, class 6, transcription factor 1	109	0.48
chr9_106821518_106822739	18.42	Dcaf1	DDB1 and CUL4 associated factor 1	254	0.89
chr2_44926591_44927289	18.38	Gtdc1	glycosyltransferase-like domain containing 1	209	0.96
chr13_119258613_119258805	18.22	Gm44488	predicted gene, 44488	10895	0.22
chr17_29490421_29490815	18.06	Pim1	proviral integration site 1	135	0.84
chr12_118301013_118301849	18.02	Sp4	trans-acting transcription factor 4	9	0.99
chr11_88068171_88069196	17.90	Vezf1	vascular endothelial zinc finger 1	404	0.76
chr15_58140746_58142050	17.83	Wdyhv1	WDYHV motif containing 1	6	0.96
chr10_61534398_61535221	17.83	Gm17829	predicted gene, 17829	24224	0.1
chr14_40966316_40967615	17.83	Tspan14	tetraspanin 14	158	0.96
chr15_100747217_100747460	17.81	Slc4a8	solute carrier family 4 (anion exchanger), member 8	14409	0.11
chr7_133710940_133711141	17.47	Uros	uroporphyrinogen III synthase	968	0.37
chr14_57912393_57912544	17.26	Micu2	mitochondrial calcium uptake 2	7464	0.17
chr7_48880950_48881793	17.13	Gm2788	predicted gene 2788	71	0.71
chr5_125441031_125441705	16.91	Bri3bp	Bri3 binding protein	200	0.9
chr11_85139345_85140659	16.89	Usp32	ubiquitin specific peptidase 32	34	0.97
chr4_107253005_107253839	16.85	Lrrc42	leucine rich repeat containing 42	110	0.58
chr9_59750348_59751247	16.83	Senp8	SUMO/sentrin specific peptidase 8	87	0.51
chr12_101028530_101029714	16.77	Ccdc88c	coiled-coil domain containing 88C	66	0.95
chr12_86883989_86885134	16.74	Irf2bpl	interferon regulatory factor 2 binding protein-like	237	0.93
chr2_156840246_156841082	16.67	Tgif2	TGFB-induced factor homeobox 2	358	0.63
chr10_77606403_77607161	16.64	Sumo3	small ubiquitin-like modifier 3	211	0.75
chrX_36988645_36990253	16.56	Septin6	septin 6	42	0.97
chrX_13070554_13071574	16.53	Usp9x	ubiquitin specific peptidase 9, X chromosome	434	0.84
chr5_139380266_139381195	16.47	Gpr146	G protein-coupled receptor 146	149	0.92
chr11_48816528_48817196	16.45	Trim41	tripartite motif-containing 41	91	0.93
chr14_14351950_14353283	16.45	Il3ra	interleukin 3 receptor, alpha chain	2995	0.15
chr12_76709620_76710348	16.40	Sptb	spectrin beta, erythrocytic	39	0.98
chr17_47923769_47925323	16.22	Foxp4	forkhead box P4	70	0.96
chrY_90771840_90772811	16.02	Gm47283	predicted gene, 47283	12413	0.17
chr4_152086414_152087408	16.02	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	53	0.96
chr2_165326390_165327162	15.99	Elmo2	engulfment and cell motility 2	297	0.87
chr11_95990909_95991822	15.92	Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	8754	0.09
chr6_49367200_49368123	15.77	Fam221a	family with sequence similarity 221, member A	78	0.97
chr5_137349031_137350198	15.76	Ephb4	Eph receptor B4	495	0.62
chr12_105009915_105010683	15.75	Syne3	spectrin repeat containing, nuclear envelope family member 3	490	0.67
chr17_88065293_88066116	15.72	Fbxo11	F-box protein 11	413	0.86
chr11_102393202_102394154	15.63	Rundc3a	RUN domain containing 3A	275	0.82
chr3_88532663_88533971	15.62	Mex3a	mex3 RNA binding family member A	922	0.31
chr11_117968531_117970182	15.58	Socs3	suppressor of cytokine signaling 3	95	0.96
chr14_32022577_32022765	15.58	Galnt15	polypeptide N-acetylgalactosaminyltransferase 15	6318	0.15
chr3_87910469_87910885	15.53	Hdgf	heparin binding growth factor	643	0.53
chr19_29805752_29806710	15.47	9930021J03Rik	RIKEN cDNA 9930021J03 gene	242	0.68
chr11_69837611_69838644	15.30	Nlgn2	neuroligin 2	343	0.43
chr9_44881205_44881917	15.28	Gm39326	predicted gene, 39326	167	0.6
chr5_122501856_122502977	15.27	Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	191	0.88
chr3_85887352_85888077	15.27	4933425M03Rik	RIKEN cDNA 4933425M03 gene	23	0.56
chr11_87986817_87988025	15.27	Dynll2	dynein light chain LC8-type 2	65	0.96
chr9_110653586_110654769	15.27	Nbeal2	neurobeachin-like 2	16	0.94
chr8_70698268_70700333	15.23	Jund	jun D proto-oncogene	351	0.45
chr11_97744788_97745005	15.22	Mir8102	microRNA 8102	1	0.69
chr11_97884065_97884612	15.20	Fbxo47	F-box protein 47	184	0.58
chr15_81585272_81586453	15.16	Gm23880	predicted gene, 23880	271	0.52
chr5_134551282_134552920	15.11	Gm42884	predicted gene 42884	44	0.81
chr6_90988622_90989360	15.08	Iqsec1	IQ motif and Sec7 domain 1	306	0.9
chr6_124919273_124920636	15.08	Ptms	parathymosin	149	0.88
chr14_25606696_25608421	15.06	Zmiz1	zinc finger, MIZ-type containing 1	201	0.95
chr5_107986404_107987625	15.03	Dipk1a	divergent protein kinase domain 1A	19	0.97
chr11_116581477_116581809	14.99	Ube2o	ubiquitin-conjugating enzyme E2O	196	0.88
chr8_89042876_89043891	14.95	Sall1	spalt like transcription factor 1	779	0.7
chr18_35829993_35830906	14.90	Cxxc5	CXXC finger 5	135	0.85
chr11_78163296_78164397	14.80	Traf4	TNF receptor associated factor 4	1670	0.14
chr13_58006958_58007325	14.59	Mir874	microRNA 874	16059	0.21
chr10_122096764_122097910	14.53	Rxylt1	ribitol xylosyltransferase 1	34	0.97
chr11_60176319_60177391	14.53	Rai1	retinoic acid induced 1	976	0.44
chr4_88032518_88033581	14.45	Mllt3	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3	232	0.71
chr17_33915666_33916637	14.43	Zbtb22	zinc finger and BTB domain containing 22	20	0.48
chr5_123137669_123138894	14.38	AI480526	expressed sequence AI480526	172	0.79
chr11_74925378_74926625	14.36	Srr	serine racemase	53	0.66
chr11_11684707_11686418	14.34	Gm11999	predicted gene 11999	162	0.73
chr10_127512528_127514054	14.32	Ndufa4l2	Ndufa4, mitochondrial complex associated like 2	1676	0.21
chr19_4282702_4283651	14.31	Ankrd13d	ankyrin repeat domain 13 family, member D	39	0.93
chr4_116720426_116721428	14.31	Tesk2	testis-specific kinase 2	21	0.96
chr17_35164786_35165560	14.23	Gm17705	predicted gene, 17705	54	0.72
chr1_86525613_86527056	14.15	Ptma	prothymosin alpha	392	0.81
chr8_70609185_70610414	14.14	Gm45546	predicted gene 45546	626	0.42
chr19_46499799_46500492	14.14	Trim8	tripartite motif-containing 8	1557	0.33
chr4_129513695_129514851	14.10	Marcksl1	MARCKS-like 1	692	0.46
chr2_5951282_5952030	14.05	Upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	187	0.94
chr7_83891433_83892352	14.04	Mesd	mesoderm development LRP chaperone	108	0.78
chr2_34372457_34372975	13.99	Pbx3	pre B cell leukemia homeobox 3	426	0.84
chr7_16046417_16047443	13.97	Bicra	BRD4 interacting chromatin remodeling complex associated protein	991	0.44
chr3_144720129_144720738	13.96	Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	98	0.95
chr2_30807359_30808064	13.95	Ntmt1	N-terminal Xaa-Pro-Lys N-methyltransferase 1	115	0.94
chr8_84979246_84980613	13.92	Junb	jun B proto-oncogene	1211	0.19
chr12_8770800_8772245	13.86	Sdc1	syndecan 1	109	0.78
chr2_25982690_25983958	13.83	Camsap1	calmodulin regulated spectrin-associated protein 1	42	0.97
chr15_36792317_36793249	13.81	Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	369	0.84
chr10_80590277_80590932	13.76	Abhd17a	abhydrolase domain containing 17A	263	0.71
chr11_23255157_23256431	13.75	Xpo1	exportin 1	247	0.94
chr9_101251390_101252245	13.70	Ppp2r3a	protein phosphatase 2, regulatory subunit B'', alpha	22	0.97
chr14_77483153_77483315	13.70	Gm6994	predicted gene 6994	18206	0.17
chr5_149051995_149052486	13.65	Hmgb1	high mobility group box 1	137	0.93
chr10_127667525_127668413	13.58	Nab2	Ngfi-A binding protein 2	599	0.4
chr10_42275380_42276258	13.56	Foxo3	forkhead box O3	877	0.68
chr11_116624141_116624473	13.55	Rhbdf2	rhomboid 5 homolog 2	60	0.95
chr10_128525093_128526268	13.52	Esyt1	extended synaptotagmin-like protein 1	188	0.63
chr10_127380689_127381478	13.47	R3hdm2	R3H domain containing 2	284	0.81
chr11_60114297_60115906	13.45	4930412M03Rik	RIKEN cDNA 4930412M03 gene	129	0.95
chr2_154790876_154791702	13.45	Raly	hnRNP-associated with lethal yellow	63	0.56
chr11_102407017_102407912	13.43	Slc25a39	solute carrier family 25, member 39	1	0.95
chr10_42950072_42950669	13.41	Scml4	Scm polycomb group protein like 4	10489	0.19
chr9_106367425_106368835	13.38	Dusp7	dual specificity phosphatase 7	502	0.7
chr5_134467312_134467605	13.33	Gm16020	predicted gene 16020	4218	0.12
chr4_16163506_16164146	13.28	Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	179	0.63
chr12_72085046_72085908	13.23	L3hypdh	L-3-hydroxyproline dehydratase (trans-)	38	0.58
chr16_30063252_30064537	13.19	Hes1	hes family bHLH transcription factor 1	490	0.76
chr9_35116070_35117303	13.19	4930581F22Rik	RIKEN cDNA 4930581F22 gene	42	0.69
chr9_62980541_62981320	13.17	Pias1	protein inhibitor of activated STAT 1	47	0.98
chr11_51999751_52000565	13.16	Ube2b	ubiquitin-conjugating enzyme E2B	321	0.69
chr7_25281840_25282218	13.14	Cic	capicua transcriptional repressor	150	0.9
chr2_18056522_18056740	13.12	1810059C17Rik	RIKEN cDNA 1810059C17 gene	18	0.93
chr5_137530580_137532081	13.12	Gnb2	guanine nucleotide binding protein (G protein), beta 2	33	0.9
chr15_99295125_99295746	13.11	Prpf40b	pre-mRNA processing factor 40B	164	0.76
chr9_108094451_108094983	13.08	Apeh	acylpeptide hydrolase	111	0.9
chr16_93711386_93712056	13.08	Dop1b	DOP1 leucine zipper like protein B	183	0.93
chr12_51691136_51692207	13.08	Strn3	striatin, calmodulin binding protein 3	216	0.81
chr4_133967146_133967733	13.03	Hmgn2	high mobility group nucleosomal binding domain 2	2	0.97
chr10_127188430_127189698	13.02	Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	292	0.77
chr3_35753734_35754344	13.00	Atp11b	ATPase, class VI, type 11B	67	0.97
chr7_44985781_44987176	12.98	Prmt1	protein arginine N-methyltransferase 1	14	0.83
chr6_113377357_113377672	12.96	Tada3	transcriptional adaptor 3	3	0.89
chr2_104122426_104123415	12.93	A930018P22Rik	RIKEN cDNA A930018P22 gene	151	0.94
chr10_69908447_69908713	12.93	Ank3	ankyrin 3, epithelial	6285	0.32
chr4_155563302_155563634	12.92	Nadk	NAD kinase	232	0.87
chr7_65644408_65645427	12.91	Tarsl2	threonyl-tRNA synthetase-like 2	19	0.98
chr12_108179279_108180127	12.90	Ccnk	cyclin K	35	0.86
chr6_83456116_83457458	12.89	Tet3	tet methylcytosine dioxygenase 3	395	0.77
chr7_128610983_128611399	12.88	Inpp5f	inositol polyphosphate-5-phosphatase F	137	0.94
chr15_76697423_76698657	12.85	Gpt	glutamic pyruvic transaminase, soluble	22	0.93
chr10_80538778_80539361	12.77	Atp8b3	ATPase, class I, type 8B, member 3	21	0.95
chr11_101467552_101468698	12.73	Rnd2	Rho family GTPase 2	50	0.92

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.6	34.7	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
11.5	34.6	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
10.8	32.3	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
10.7	32.0	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
10.6	42.4	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
10.4	31.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
10.1	20.3	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
10.0	30.0	GO:0040031	snRNA modification(GO:0040031)
9.7	29.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
9.4	28.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
9.2	27.7	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
9.2	27.7	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
9.0	45.1	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
8.9	26.8	GO:0071314	cellular response to cocaine(GO:0071314)
8.6	17.3	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
8.6	25.7	GO:0021553	olfactory nerve development(GO:0021553)
8.5	25.4	GO:0008050	female courtship behavior(GO:0008050)
8.3	33.2	GO:0006344	maintenance of chromatin silencing(GO:0006344)
8.3	33.0	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
8.1	24.4	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
8.1	24.2	GO:0070889	platelet alpha granule organization(GO:0070889)
8.0	16.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
8.0	16.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
8.0	23.9	GO:0006741	NADP biosynthetic process(GO:0006741)
7.8	31.2	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
7.8	23.3	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
7.7	23.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
7.6	22.7	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
7.3	29.3	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
7.2	21.6	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
7.1	21.4	GO:0007525	somatic muscle development(GO:0007525)
7.1	7.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
7.0	28.1	GO:0023021	termination of signal transduction(GO:0023021)
6.9	27.6	GO:0097039	protein linear polyubiquitination(GO:0097039)
6.8	34.0	GO:0072553	terminal button organization(GO:0072553)
6.8	40.5	GO:0034770	histone H4-K20 methylation(GO:0034770)
6.7	33.5	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
6.6	66.4	GO:0034063	stress granule assembly(GO:0034063)
6.6	33.2	GO:0060789	hair follicle placode formation(GO:0060789)
6.6	26.5	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
6.6	19.7	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
6.5	13.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
6.5	32.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
6.4	38.6	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
6.4	25.7	GO:0051660	establishment of centrosome localization(GO:0051660)
6.4	6.4	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
6.4	19.1	GO:0002432	granuloma formation(GO:0002432)
6.3	37.8	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
6.3	25.1	GO:0090168	Golgi reassembly(GO:0090168)
6.3	68.9	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
6.2	12.4	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
6.2	12.3	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
6.1	12.2	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
6.1	30.5	GO:1903276	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
6.0	23.8	GO:0046292	formaldehyde metabolic process(GO:0046292)
5.9	35.5	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
5.9	23.5	GO:0048625	myoblast fate commitment(GO:0048625)
5.9	35.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
5.8	29.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
5.8	28.8	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
5.7	22.9	GO:0007296	vitellogenesis(GO:0007296)
5.7	17.2	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
5.7	28.6	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
5.6	16.9	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
5.6	22.4	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
5.6	16.8	GO:1903061	positive regulation of protein lipidation(GO:1903061)
5.6	16.7	GO:0046208	spermine catabolic process(GO:0046208)
5.4	136.0	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
5.4	16.3	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
5.4	26.9	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
5.4	21.4	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
5.4	16.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
5.3	10.7	GO:0045472	response to ether(GO:0045472)
5.3	15.9	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
5.3	21.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
5.3	26.3	GO:1905214	regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
5.2	15.7	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
5.2	15.7	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
5.2	10.3	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
5.2	5.2	GO:0002572	pro-T cell differentiation(GO:0002572)
5.2	15.5	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
5.1	15.4	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
5.1	15.4	GO:0006543	glutamine catabolic process(GO:0006543)
5.1	25.5	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
5.1	15.2	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
5.1	20.3	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
5.1	15.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
5.0	19.9	GO:0060623	regulation of chromosome condensation(GO:0060623)
5.0	19.8	GO:0097460	ferrous iron import into cell(GO:0097460)
4.9	14.8	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
4.9	14.8	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
4.9	14.7	GO:0044838	cell quiescence(GO:0044838)
4.9	24.5	GO:0050812	regulation of acyl-CoA biosynthetic process(GO:0050812)
4.9	14.7	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
4.8	9.7	GO:0035928	rRNA import into mitochondrion(GO:0035928)
4.8	19.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
4.8	9.6	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
4.8	19.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
4.8	14.4	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
4.8	28.7	GO:0070544	histone H3-K36 demethylation(GO:0070544)
4.8	4.8	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
4.7	19.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
4.7	14.1	GO:0045585	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
4.7	28.2	GO:0070933	histone H4 deacetylation(GO:0070933)
4.6	27.9	GO:0048227	plasma membrane to endosome transport(GO:0048227)
4.6	18.5	GO:0060480	lung goblet cell differentiation(GO:0060480)
4.6	9.3	GO:0032907	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
4.6	18.5	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
4.6	13.7	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
4.6	13.7	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
4.5	22.6	GO:0010668	ectodermal cell differentiation(GO:0010668)
4.5	67.7	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
4.5	22.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
4.5	4.5	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
4.5	31.3	GO:0001842	neural fold formation(GO:0001842)
4.5	4.5	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
4.4	26.7	GO:0034720	histone H3-K4 demethylation(GO:0034720)
4.4	26.6	GO:0016266	O-glycan processing(GO:0016266)
4.4	17.7	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
4.4	13.3	GO:0042117	monocyte activation(GO:0042117)
4.4	13.3	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
4.4	39.8	GO:0061032	visceral serous pericardium development(GO:0061032)
4.4	8.8	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
4.4	17.6	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
4.4	4.4	GO:0006680	glucosylceramide catabolic process(GO:0006680)
4.4	30.5	GO:0035811	negative regulation of urine volume(GO:0035811)
4.3	30.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
4.3	21.6	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
4.3	17.3	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
4.3	4.3	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
4.3	30.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
4.3	17.2	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
4.3	12.8	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
4.2	12.7	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
4.2	55.0	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
4.2	4.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
4.2	16.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
4.2	16.7	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
4.2	16.7	GO:0031581	hemidesmosome assembly(GO:0031581)
4.2	16.7	GO:0006166	purine ribonucleoside salvage(GO:0006166)
4.2	12.5	GO:0061738	late endosomal microautophagy(GO:0061738)
4.2	20.8	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
4.2	12.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
4.2	20.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
4.2	29.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
4.1	8.3	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
4.1	41.4	GO:0035518	histone H2A monoubiquitination(GO:0035518)
4.1	4.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
4.1	20.5	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
4.1	4.1	GO:0036258	multivesicular body assembly(GO:0036258)
4.1	8.2	GO:1990705	cholangiocyte proliferation(GO:1990705)
4.1	12.2	GO:2000774	positive regulation of cellular senescence(GO:2000774)
4.1	16.3	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
4.1	16.3	GO:0061635	regulation of protein complex stability(GO:0061635)
4.1	20.3	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
4.0	20.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
4.0	12.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
4.0	12.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
4.0	48.4	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
4.0	12.0	GO:0042938	dipeptide transport(GO:0042938)
4.0	8.0	GO:0061687	detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
4.0	16.0	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
4.0	12.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
4.0	11.9	GO:0001922	B-1 B cell homeostasis(GO:0001922)
4.0	15.8	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
3.9	19.7	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
3.9	15.7	GO:0051541	elastin metabolic process(GO:0051541)
3.9	11.8	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
3.9	11.8	GO:0034499	late endosome to Golgi transport(GO:0034499)
3.9	31.4	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
3.9	23.4	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
3.9	3.9	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
3.9	11.7	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
3.9	3.9	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
3.9	7.8	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
3.9	34.9	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
3.9	3.9	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
3.9	15.5	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
3.9	11.6	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
3.8	23.1	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
3.8	15.4	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
3.8	15.3	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
3.8	3.8	GO:0060374	mast cell differentiation(GO:0060374)
3.8	11.5	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
3.8	19.0	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929)
3.8	7.6	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
3.8	7.5	GO:1903416	response to glycoside(GO:1903416)
3.8	7.5	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
3.8	7.5	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
3.7	7.5	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.7	7.5	GO:0061620	glycolytic process through glucose-6-phosphate(GO:0061620)
3.7	29.7	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
3.7	3.7	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
3.7	3.7	GO:0090343	positive regulation of cell aging(GO:0090343)
3.6	10.9	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
3.6	14.5	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
3.6	7.3	GO:0006678	glucosylceramide metabolic process(GO:0006678)
3.6	25.4	GO:0031507	heterochromatin assembly(GO:0031507)
3.6	21.8	GO:0046874	quinolinate metabolic process(GO:0046874)
3.6	14.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
3.6	18.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
3.6	3.6	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.6	7.1	GO:1903334	positive regulation of protein folding(GO:1903334)
3.6	10.7	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
3.5	24.7	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
3.5	21.2	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
3.5	45.5	GO:0045116	protein neddylation(GO:0045116)
3.5	17.5	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
3.5	3.5	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
3.5	10.5	GO:0000710	meiotic mismatch repair(GO:0000710)
3.5	7.0	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
3.5	13.9	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
3.5	10.4	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
3.5	34.7	GO:0051352	negative regulation of ligase activity(GO:0051352)
3.4	13.7	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
3.4	37.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
3.4	6.8	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
3.4	13.6	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
3.4	37.5	GO:0007035	vacuolar acidification(GO:0007035)
3.4	27.2	GO:0002115	store-operated calcium entry(GO:0002115)
3.4	23.7	GO:0000059	protein import into nucleus, docking(GO:0000059)
3.4	16.9	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
3.4	16.9	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
3.4	6.7	GO:0090239	regulation of histone H4 acetylation(GO:0090239)
3.4	10.1	GO:0000087	mitotic M phase(GO:0000087)
3.4	10.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
3.4	3.4	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
3.3	10.0	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
3.3	6.7	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719)
3.3	10.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
3.3	10.0	GO:0048388	endosomal lumen acidification(GO:0048388)
3.3	59.9	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
3.3	36.5	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
3.3	19.8	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
3.3	13.2	GO:0048102	autophagic cell death(GO:0048102)
3.3	9.9	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
3.3	3.3	GO:0018992	germ-line sex determination(GO:0018992)
3.3	26.3	GO:0048680	positive regulation of axon regeneration(GO:0048680)
3.3	19.7	GO:0051013	microtubule severing(GO:0051013)
3.3	13.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
3.3	9.8	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.3	3.3	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501) regulation of hemoglobin biosynthetic process(GO:0046984)
3.3	9.8	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
3.2	6.5	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.2	9.7	GO:0009826	unidimensional cell growth(GO:0009826)
3.2	9.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
3.2	9.7	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
3.2	67.9	GO:0016578	histone deubiquitination(GO:0016578)
3.2	22.6	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
3.2	3.2	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
3.2	9.7	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
3.2	9.6	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
3.2	22.5	GO:0006563	L-serine metabolic process(GO:0006563)
3.2	12.8	GO:0070828	heterochromatin organization(GO:0070828)
3.2	25.6	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
3.2	12.8	GO:0021698	cerebellar cortex structural organization(GO:0021698)
3.2	19.1	GO:0016574	histone ubiquitination(GO:0016574)
3.2	15.9	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
3.2	9.5	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
3.2	6.3	GO:0032803	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
3.2	9.5	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
3.1	22.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
3.1	22.0	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
3.1	15.7	GO:0046487	glyoxylate metabolic process(GO:0046487)
3.1	6.3	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
3.1	25.1	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
3.1	9.4	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
3.1	9.4	GO:0061157	mRNA destabilization(GO:0061157)
3.1	9.4	GO:0006449	regulation of translational termination(GO:0006449)
3.1	6.3	GO:0010985	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
3.1	9.4	GO:0019086	late viral transcription(GO:0019086)
3.1	3.1	GO:0006551	leucine metabolic process(GO:0006551)
3.1	3.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
3.1	3.1	GO:0046655	folic acid metabolic process(GO:0046655)
3.1	12.4	GO:1904354	negative regulation of telomere capping(GO:1904354)
3.1	6.2	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
3.1	6.2	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
3.1	3.1	GO:0003166	bundle of His development(GO:0003166)
3.1	9.3	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
3.1	9.2	GO:0072718	response to cisplatin(GO:0072718)
3.1	9.2	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
3.1	6.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
3.1	12.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
3.0	12.2	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
3.0	9.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
3.0	12.1	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
3.0	6.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
3.0	9.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
3.0	21.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
3.0	15.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
3.0	24.1	GO:0045792	negative regulation of cell size(GO:0045792)
3.0	6.0	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
3.0	12.0	GO:0014043	negative regulation of neuron maturation(GO:0014043)
3.0	6.0	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
3.0	9.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
3.0	15.0	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
3.0	27.0	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
3.0	6.0	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
3.0	3.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
3.0	8.9	GO:0034421	post-translational protein acetylation(GO:0034421)
3.0	3.0	GO:0010255	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
3.0	5.9	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.0	8.9	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
3.0	8.9	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
3.0	5.9	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
3.0	8.9	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
3.0	3.0	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
2.9	14.7	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
2.9	8.8	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
2.9	8.8	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
2.9	5.9	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.9	102.9	GO:0006513	protein monoubiquitination(GO:0006513)
2.9	8.8	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
2.9	20.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
2.9	14.5	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
2.9	20.3	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
2.9	14.5	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
2.9	8.7	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
2.9	14.4	GO:0006572	tyrosine catabolic process(GO:0006572)
2.9	11.5	GO:0044827	modulation by host of viral genome replication(GO:0044827)
2.9	5.8	GO:0010040	response to iron(II) ion(GO:0010040)
2.9	14.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
2.9	8.6	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.9	20.1	GO:0035372	protein localization to microtubule(GO:0035372)
2.9	17.1	GO:0006004	fucose metabolic process(GO:0006004)
2.9	8.6	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
2.9	11.4	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
2.8	8.5	GO:0006007	glucose catabolic process(GO:0006007)
2.8	28.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
2.8	19.9	GO:0046040	IMP metabolic process(GO:0046040)
2.8	14.2	GO:0070874	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
2.8	8.5	GO:0015817	histidine transport(GO:0015817)
2.8	17.0	GO:0035459	cargo loading into vesicle(GO:0035459)
2.8	8.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
2.8	14.2	GO:2000662	interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) regulation of interleukin-13 secretion(GO:2000665)
2.8	33.9	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
2.8	5.6	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
2.8	36.5	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
2.8	2.8	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
2.8	8.4	GO:0034405	response to fluid shear stress(GO:0034405)
2.8	5.6	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
2.8	2.8	GO:0043320	natural killer cell degranulation(GO:0043320)
2.8	16.7	GO:0043173	nucleotide salvage(GO:0043173)
2.8	13.8	GO:0048194	Golgi vesicle budding(GO:0048194)
2.8	22.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
2.8	8.3	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
2.8	8.3	GO:0046104	thymidine metabolic process(GO:0046104)
2.7	74.1	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
2.7	5.5	GO:0019042	viral latency(GO:0019042)
2.7	8.2	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
2.7	8.2	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
2.7	13.7	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
2.7	5.5	GO:0010452	histone H3-K36 methylation(GO:0010452)
2.7	13.6	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
2.7	8.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
2.7	8.2	GO:0035562	negative regulation of chromatin binding(GO:0035562)
2.7	29.9	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
2.7	2.7	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
2.7	10.8	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
2.7	8.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
2.7	2.7	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.7	16.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
2.7	16.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
2.7	18.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.7	16.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
2.7	18.9	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
2.7	5.4	GO:0006600	creatine metabolic process(GO:0006600)
2.7	8.1	GO:0080009	mRNA methylation(GO:0080009)
2.7	2.7	GO:0034587	piRNA metabolic process(GO:0034587)
2.7	5.4	GO:0060544	regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546)
2.7	8.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
2.7	5.4	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
2.7	72.4	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
2.7	8.0	GO:0003096	renal sodium ion transport(GO:0003096)
2.7	2.7	GO:1904467	regulation of tumor necrosis factor secretion(GO:1904467) positive regulation of tumor necrosis factor secretion(GO:1904469) tumor necrosis factor secretion(GO:1990774)
2.7	2.7	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
2.7	16.0	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
2.7	8.0	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
2.7	8.0	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
2.7	13.3	GO:0050686	negative regulation of mRNA processing(GO:0050686)
2.6	7.9	GO:2000870	regulation of progesterone secretion(GO:2000870)
2.6	10.6	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
2.6	23.7	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
2.6	2.6	GO:0061470	T follicular helper cell differentiation(GO:0061470)
2.6	5.2	GO:0032204	regulation of telomere maintenance(GO:0032204)
2.6	34.1	GO:0006376	mRNA splice site selection(GO:0006376)
2.6	7.9	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
2.6	15.7	GO:0090166	Golgi disassembly(GO:0090166)
2.6	7.8	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
2.6	7.8	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
2.6	2.6	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
2.6	12.9	GO:0061615	glycolytic process through fructose-6-phosphate(GO:0061615)
2.6	15.5	GO:0043486	histone exchange(GO:0043486)
2.6	7.7	GO:0051409	response to nitrosative stress(GO:0051409)
2.6	46.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
2.6	2.6	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
2.5	2.5	GO:0001969	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
2.5	5.1	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
2.5	5.1	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
2.5	2.5	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
2.5	5.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
2.5	7.6	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
2.5	12.6	GO:1902669	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
2.5	7.5	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
2.5	5.0	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
2.5	7.5	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
2.5	17.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
2.5	7.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
2.5	12.5	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
2.5	7.5	GO:0030575	nuclear body organization(GO:0030575)
2.5	5.0	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
2.5	12.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
2.5	7.5	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
2.5	14.9	GO:0050917	sensory perception of umami taste(GO:0050917)
2.5	14.9	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
2.5	17.3	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.5	9.9	GO:0046185	aldehyde catabolic process(GO:0046185)
2.5	2.5	GO:0034114	regulation of heterotypic cell-cell adhesion(GO:0034114)
2.5	27.1	GO:0043968	histone H2A acetylation(GO:0043968)
2.5	2.5	GO:0090289	regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
2.5	4.9	GO:0061043	regulation of vascular wound healing(GO:0061043)
2.5	9.8	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
2.5	24.5	GO:0006107	oxaloacetate metabolic process(GO:0006107)
2.4	7.3	GO:0071462	cellular response to water stimulus(GO:0071462)
2.4	7.3	GO:1900221	regulation of beta-amyloid clearance(GO:1900221)
2.4	7.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
2.4	24.3	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
2.4	7.3	GO:0015819	lysine transport(GO:0015819)
2.4	2.4	GO:0006982	response to lipid hydroperoxide(GO:0006982)
2.4	4.8	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
2.4	19.3	GO:0051198	negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
2.4	4.8	GO:0045900	negative regulation of translational elongation(GO:0045900)
2.4	24.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
2.4	4.8	GO:0045054	constitutive secretory pathway(GO:0045054)
2.4	9.6	GO:0036089	cleavage furrow formation(GO:0036089)
2.4	2.4	GO:0050779	RNA destabilization(GO:0050779)
2.4	7.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.4	4.8	GO:0010212	response to ionizing radiation(GO:0010212)
2.4	16.8	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
2.4	2.4	GO:0000966	RNA 5'-end processing(GO:0000966)
2.4	4.8	GO:0031269	pseudopodium assembly(GO:0031269)
2.4	4.7	GO:0018343	protein farnesylation(GO:0018343)
2.4	11.8	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
2.4	14.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
2.4	9.4	GO:0015886	heme transport(GO:0015886)
2.3	30.5	GO:0006144	purine nucleobase metabolic process(GO:0006144)
2.3	28.1	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
2.3	11.7	GO:0042373	vitamin K metabolic process(GO:0042373)
2.3	9.3	GO:1903147	negative regulation of mitophagy(GO:1903147)
2.3	13.9	GO:0060613	fat pad development(GO:0060613)
2.3	11.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
2.3	4.6	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
2.3	23.0	GO:0046685	response to arsenic-containing substance(GO:0046685)
2.3	6.9	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
2.3	6.9	GO:0046600	negative regulation of centriole replication(GO:0046600)
2.3	20.7	GO:0060712	spongiotrophoblast layer development(GO:0060712)
2.3	6.9	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
2.3	2.3	GO:0010796	regulation of multivesicular body size(GO:0010796)
2.3	9.2	GO:0006102	isocitrate metabolic process(GO:0006102)
2.3	16.1	GO:0015838	amino-acid betaine transport(GO:0015838)
2.3	20.6	GO:0006662	glycerol ether metabolic process(GO:0006662)
2.3	29.7	GO:0006098	pentose-phosphate shunt(GO:0006098)
2.3	9.1	GO:0031053	primary miRNA processing(GO:0031053)
2.3	2.3	GO:0097527	necroptotic signaling pathway(GO:0097527)
2.3	22.7	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
2.3	65.8	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
2.3	6.8	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
2.3	22.6	GO:0034204	lipid translocation(GO:0034204)
2.2	6.7	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.2	6.7	GO:0071280	cellular response to copper ion(GO:0071280)
2.2	4.5	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.2	9.0	GO:0072675	osteoclast fusion(GO:0072675)
2.2	6.7	GO:0006573	valine metabolic process(GO:0006573)
2.2	31.4	GO:0006301	postreplication repair(GO:0006301)
2.2	2.2	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
2.2	22.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
2.2	4.5	GO:0060903	positive regulation of meiosis I(GO:0060903)
2.2	4.5	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
2.2	6.7	GO:0006481	C-terminal protein methylation(GO:0006481)
2.2	20.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
2.2	8.9	GO:0090170	regulation of Golgi inheritance(GO:0090170)
2.2	6.7	GO:0006287	base-excision repair, gap-filling(GO:0006287)
2.2	2.2	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
2.2	4.4	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
2.2	8.8	GO:0046218	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
2.2	4.4	GO:0003011	involuntary skeletal muscle contraction(GO:0003011)
2.2	4.4	GO:0003072	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
2.2	11.0	GO:0032801	receptor catabolic process(GO:0032801)
2.2	8.8	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
2.2	13.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
2.2	17.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
2.2	6.6	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
2.2	4.4	GO:1903525	regulation of membrane tubulation(GO:1903525)
2.2	28.5	GO:0044783	mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783)
2.2	4.4	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
2.2	13.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
2.2	2.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
2.2	10.9	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
2.2	4.4	GO:0043504	mitochondrial DNA repair(GO:0043504)
2.2	2.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
2.2	97.9	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
2.2	6.5	GO:0098787	mRNA cleavage involved in mRNA processing(GO:0098787)
2.2	4.3	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
2.2	17.3	GO:0021670	lateral ventricle development(GO:0021670)
2.2	2.2	GO:0044532	modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) modulation by symbiont of host programmed cell death(GO:0052040) modulation by symbiont of host apoptotic process(GO:0052150) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433)
2.2	6.5	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
2.2	19.4	GO:0009301	snRNA transcription(GO:0009301)
2.2	23.7	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
2.2	2.2	GO:0071616	thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616)
2.1	8.6	GO:0070126	mitochondrial translational termination(GO:0070126)
2.1	2.1	GO:0050904	diapedesis(GO:0050904)
2.1	10.7	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
2.1	6.4	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
2.1	19.3	GO:0038092	nodal signaling pathway(GO:0038092)
2.1	19.3	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
2.1	12.8	GO:0032782	bile acid secretion(GO:0032782)
2.1	12.8	GO:0015858	nucleoside transport(GO:0015858)
2.1	2.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
2.1	2.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
2.1	2.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.1	42.5	GO:0016073	snRNA metabolic process(GO:0016073)
2.1	42.5	GO:0016239	positive regulation of macroautophagy(GO:0016239)
2.1	4.2	GO:0006285	base-excision repair, AP site formation(GO:0006285)
2.1	8.5	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
2.1	31.8	GO:2000785	regulation of autophagosome assembly(GO:2000785)
2.1	6.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.1	14.8	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
2.1	4.2	GO:0035973	aggrephagy(GO:0035973)
2.1	4.2	GO:0030576	Cajal body organization(GO:0030576)
2.1	4.2	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
2.1	10.5	GO:0046060	dATP metabolic process(GO:0046060)
2.1	10.4	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
2.1	45.9	GO:0000186	activation of MAPKK activity(GO:0000186)
2.1	10.4	GO:0039529	RIG-I signaling pathway(GO:0039529)
2.1	2.1	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
2.1	4.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.1	8.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
2.1	4.1	GO:0021747	cochlear nucleus development(GO:0021747)
2.1	10.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.1	4.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
2.1	4.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
2.1	2.1	GO:0006625	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
2.1	2.1	GO:0030242	pexophagy(GO:0030242)
2.1	12.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
2.1	4.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
2.1	12.3	GO:0046599	regulation of centriole replication(GO:0046599)
2.0	4.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
2.0	2.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
2.0	10.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
2.0	6.1	GO:0006177	GMP biosynthetic process(GO:0006177)
2.0	2.0	GO:1901096	regulation of autophagosome maturation(GO:1901096)
2.0	2.0	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
2.0	12.1	GO:0060177	regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
2.0	18.2	GO:0051383	kinetochore organization(GO:0051383)
2.0	8.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
2.0	14.1	GO:0034508	centromere complex assembly(GO:0034508)
2.0	2.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
2.0	14.0	GO:0071318	cellular response to ATP(GO:0071318)
2.0	8.0	GO:0044857	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
2.0	75.9	GO:0007569	cell aging(GO:0007569)
2.0	6.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.0	2.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
2.0	13.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
2.0	2.0	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
2.0	39.6	GO:0018208	peptidyl-proline modification(GO:0018208)
2.0	2.0	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
2.0	5.9	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
2.0	5.9	GO:0042732	D-xylose metabolic process(GO:0042732)
2.0	3.9	GO:1902075	cellular response to salt(GO:1902075)
2.0	5.9	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
2.0	15.7	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
2.0	9.8	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
2.0	5.9	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
2.0	5.9	GO:0006642	triglyceride mobilization(GO:0006642)
1.9	3.9	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
1.9	5.8	GO:0002328	pro-B cell differentiation(GO:0002328)
1.9	5.8	GO:0021699	cerebellar cortex maturation(GO:0021699)
1.9	5.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
1.9	1.9	GO:0046033	AMP metabolic process(GO:0046033)
1.9	3.9	GO:0060192	negative regulation of lipase activity(GO:0060192)
1.9	5.8	GO:0032439	endosome localization(GO:0032439)
1.9	7.7	GO:0006526	arginine biosynthetic process(GO:0006526)
1.9	5.8	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
1.9	7.7	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
1.9	3.8	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
1.9	7.6	GO:0035066	positive regulation of histone acetylation(GO:0035066)
1.9	3.8	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
1.9	7.6	GO:0006333	chromatin assembly or disassembly(GO:0006333)
1.9	32.4	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
1.9	7.6	GO:0018101	protein citrullination(GO:0018101)
1.9	1.9	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977)
1.9	15.1	GO:0008343	adult feeding behavior(GO:0008343)
1.9	18.8	GO:0035767	endothelial cell chemotaxis(GO:0035767)
1.9	5.7	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.9	16.9	GO:0042416	dopamine biosynthetic process(GO:0042416)
1.9	13.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
1.9	1.9	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.9	5.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
1.9	5.6	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
1.9	1.9	GO:0048769	sarcomerogenesis(GO:0048769)
1.9	7.5	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
1.9	3.7	GO:0006701	progesterone biosynthetic process(GO:0006701)
1.9	5.6	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.9	20.4	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
1.9	3.7	GO:0035461	vitamin transmembrane transport(GO:0035461)
1.8	1.8	GO:0036302	atrioventricular canal development(GO:0036302)
1.8	5.5	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
1.8	11.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
1.8	5.5	GO:0015705	iodide transport(GO:0015705)
1.8	9.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.8	16.5	GO:0007076	mitotic chromosome condensation(GO:0007076)
1.8	3.7	GO:1902969	mitotic DNA replication(GO:1902969)
1.8	3.6	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
1.8	3.6	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
1.8	3.6	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.8	3.6	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
1.8	32.7	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
1.8	3.6	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
1.8	12.6	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
1.8	17.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
1.8	10.7	GO:0043249	erythrocyte maturation(GO:0043249)
1.8	39.2	GO:0032922	circadian regulation of gene expression(GO:0032922)
1.8	3.5	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
1.8	23.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
1.8	3.5	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
1.8	5.3	GO:0001866	NK T cell proliferation(GO:0001866)
1.8	7.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.8	24.7	GO:0010762	regulation of fibroblast migration(GO:0010762)
1.8	1.8	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
1.8	8.8	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
1.8	1.8	GO:0060297	regulation of sarcomere organization(GO:0060297)
1.8	7.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.8	1.8	GO:2000468	regulation of peroxidase activity(GO:2000468)
1.8	5.3	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7	3.5	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
1.7	5.2	GO:0006670	sphingosine metabolic process(GO:0006670)
1.7	3.5	GO:0090559	regulation of membrane permeability(GO:0090559)
1.7	5.2	GO:0006057	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
1.7	7.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
1.7	1.7	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
1.7	3.5	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
1.7	12.2	GO:0071696	ectodermal placode formation(GO:0060788) ectodermal placode development(GO:0071696) ectodermal placode morphogenesis(GO:0071697)
1.7	13.9	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.7	1.7	GO:0043379	memory T cell differentiation(GO:0043379)
1.7	15.6	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
1.7	41.5	GO:0043966	histone H3 acetylation(GO:0043966)
1.7	1.7	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
1.7	10.4	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
1.7	1.7	GO:0006167	AMP biosynthetic process(GO:0006167)
1.7	6.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.7	31.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
1.7	1.7	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
1.7	6.9	GO:0090527	actin filament reorganization(GO:0090527)
1.7	1.7	GO:0001923	B-1 B cell differentiation(GO:0001923)
1.7	1.7	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
1.7	25.7	GO:0016575	histone deacetylation(GO:0016575)
1.7	12.0	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.7	3.4	GO:1901563	response to camptothecin(GO:1901563)
1.7	3.4	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.7	1.7	GO:0003162	atrioventricular node development(GO:0003162)
1.7	3.4	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
1.7	5.1	GO:0000052	citrulline metabolic process(GO:0000052)
1.7	5.1	GO:0072697	protein localization to cell cortex(GO:0072697)
1.7	8.5	GO:0017014	protein nitrosylation(GO:0017014)
1.7	11.9	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
1.7	13.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
1.7	8.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
1.7	3.4	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
1.7	18.6	GO:0035493	SNARE complex assembly(GO:0035493)
1.7	3.4	GO:0015936	coenzyme A metabolic process(GO:0015936)
1.7	6.8	GO:0000212	meiotic spindle organization(GO:0000212)
1.7	5.1	GO:0048478	replication fork protection(GO:0048478)
1.7	5.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
1.7	8.4	GO:0006561	proline biosynthetic process(GO:0006561)
1.7	1.7	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
1.7	1.7	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
1.7	3.4	GO:0042993	positive regulation of transcription factor import into nucleus(GO:0042993)
1.7	1.7	GO:0051657	maintenance of organelle location(GO:0051657)
1.7	6.7	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
1.7	15.0	GO:0030212	hyaluronan metabolic process(GO:0030212)
1.7	8.3	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.7	15.0	GO:0046686	response to cadmium ion(GO:0046686)
1.7	36.5	GO:0006338	chromatin remodeling(GO:0006338)
1.7	5.0	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
1.7	10.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
1.7	1.7	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
1.7	14.9	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
1.7	5.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
1.7	5.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
1.7	21.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
1.7	1.7	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
1.7	5.0	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
1.6	16.4	GO:0050820	positive regulation of coagulation(GO:0050820)
1.6	6.6	GO:0034498	early endosome to Golgi transport(GO:0034498)
1.6	6.6	GO:0033194	response to hydroperoxide(GO:0033194)
1.6	6.6	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
1.6	4.9	GO:0010815	bradykinin catabolic process(GO:0010815)
1.6	4.9	GO:0044773	mitotic DNA damage checkpoint(GO:0044773)
1.6	8.2	GO:0032486	Rap protein signal transduction(GO:0032486)
1.6	6.5	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.6	3.3	GO:0060215	primitive hemopoiesis(GO:0060215)
1.6	9.8	GO:0043691	reverse cholesterol transport(GO:0043691)
1.6	8.1	GO:0070475	rRNA base methylation(GO:0070475)
1.6	3.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
1.6	8.1	GO:0031167	rRNA methylation(GO:0031167)
1.6	3.2	GO:0021943	formation of radial glial scaffolds(GO:0021943)
1.6	6.5	GO:0006824	cobalt ion transport(GO:0006824)
1.6	4.8	GO:0010992	ubiquitin homeostasis(GO:0010992)
1.6	19.4	GO:0042730	fibrinolysis(GO:0042730)
1.6	3.2	GO:0044351	macropinocytosis(GO:0044351)
1.6	14.5	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
1.6	22.5	GO:0042149	cellular response to glucose starvation(GO:0042149)
1.6	1.6	GO:0060268	respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
1.6	4.8	GO:0043174	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174)
1.6	1.6	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.6	1.6	GO:0044088	regulation of vacuole organization(GO:0044088)
1.6	6.4	GO:0007000	nucleolus organization(GO:0007000)
1.6	33.5	GO:0071479	cellular response to ionizing radiation(GO:0071479)
1.6	3.2	GO:0032769	negative regulation of monooxygenase activity(GO:0032769)
1.6	8.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.6	4.8	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.6	6.4	GO:0034058	endosomal vesicle fusion(GO:0034058)
1.6	4.8	GO:0042168	heme metabolic process(GO:0042168)
1.6	6.4	GO:0036035	osteoclast development(GO:0036035)
1.6	1.6	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.6	7.9	GO:0002576	platelet degranulation(GO:0002576)
1.6	4.8	GO:0061515	myeloid cell development(GO:0061515)
1.6	7.9	GO:2000352	negative regulation of endothelial cell apoptotic process(GO:2000352)
1.6	1.6	GO:0019371	cyclooxygenase pathway(GO:0019371)
1.6	3.2	GO:0071285	cellular response to lithium ion(GO:0071285)
1.6	4.7	GO:0044786	cell cycle DNA replication(GO:0044786)
1.6	9.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
1.6	3.1	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
1.6	4.7	GO:0009838	abscission(GO:0009838)
1.6	4.7	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
1.5	1.5	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
1.5	3.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
1.5	13.9	GO:0006353	DNA-templated transcription, termination(GO:0006353)
1.5	6.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.5	9.2	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
1.5	12.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
1.5	10.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
1.5	10.7	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
1.5	13.8	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
1.5	6.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
1.5	52.1	GO:0030218	erythrocyte differentiation(GO:0030218)
1.5	3.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
1.5	6.1	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
1.5	4.6	GO:0048069	eye pigmentation(GO:0048069)
1.5	9.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
1.5	4.6	GO:0015744	succinate transport(GO:0015744)
1.5	4.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
1.5	16.7	GO:0006896	Golgi to vacuole transport(GO:0006896)
1.5	15.2	GO:0051601	exocyst localization(GO:0051601)
1.5	3.0	GO:0000237	leptotene(GO:0000237)
1.5	3.0	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
1.5	6.0	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
1.5	6.0	GO:0019695	choline metabolic process(GO:0019695)
1.5	6.0	GO:1900193	regulation of oocyte maturation(GO:1900193)
1.5	15.0	GO:0042407	cristae formation(GO:0042407)
1.5	1.5	GO:0021590	cerebellum maturation(GO:0021590)
1.5	1.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.5	16.5	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.5	37.3	GO:0071806	intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
1.5	44.6	GO:0071824	protein-DNA complex subunit organization(GO:0071824)
1.5	8.9	GO:0070327	thyroid hormone transport(GO:0070327)
1.5	3.0	GO:0033227	dsRNA transport(GO:0033227)
1.5	7.4	GO:0071711	basement membrane organization(GO:0071711)
1.5	1.5	GO:0032075	positive regulation of nuclease activity(GO:0032075)
1.5	1.5	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
1.5	7.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
1.5	4.4	GO:0051292	nuclear pore complex assembly(GO:0051292)
1.5	7.3	GO:0032648	regulation of interferon-beta production(GO:0032648)
1.5	4.4	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
1.5	1.5	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
1.4	10.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
1.4	2.9	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.4	4.3	GO:0001887	selenium compound metabolic process(GO:0001887)
1.4	13.0	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
1.4	1.4	GO:0033129	positive regulation of histone phosphorylation(GO:0033129)
1.4	5.7	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
1.4	7.1	GO:0009437	carnitine metabolic process(GO:0009437)
1.4	1.4	GO:0009074	aromatic amino acid family catabolic process(GO:0009074)
1.4	1.4	GO:0002645	positive regulation of tolerance induction(GO:0002645)
1.4	1.4	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
1.4	1.4	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
1.4	4.3	GO:0090156	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
1.4	25.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
1.4	19.9	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
1.4	9.9	GO:0035855	megakaryocyte development(GO:0035855)
1.4	2.8	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
1.4	4.2	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.4	1.4	GO:0009264	deoxyribonucleotide catabolic process(GO:0009264)
1.4	15.5	GO:0001675	acrosome assembly(GO:0001675)
1.4	5.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.4	2.8	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
1.4	2.8	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
1.4	1.4	GO:0015684	ferrous iron transport(GO:0015684)
1.4	2.8	GO:0051661	maintenance of centrosome location(GO:0051661)
1.4	5.6	GO:0045070	positive regulation of viral genome replication(GO:0045070)
1.4	1.4	GO:0007619	courtship behavior(GO:0007619)
1.4	2.8	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
1.4	1.4	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
1.4	2.7	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.4	1.4	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267)
1.4	4.1	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
1.4	4.1	GO:0098535	de novo centriole assembly(GO:0098535)
1.4	1.4	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
1.4	8.2	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
1.4	21.8	GO:0032008	positive regulation of TOR signaling(GO:0032008)
1.4	1.4	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
1.4	4.1	GO:2001252	positive regulation of chromosome organization(GO:2001252)
1.3	6.7	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
1.3	8.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.3	6.7	GO:0050434	positive regulation of viral transcription(GO:0050434)
1.3	1.3	GO:0006999	nuclear pore organization(GO:0006999)
1.3	1.3	GO:0061113	pancreas morphogenesis(GO:0061113)
1.3	5.3	GO:0030202	heparin metabolic process(GO:0030202)
1.3	4.0	GO:0090161	Golgi ribbon formation(GO:0090161)
1.3	8.0	GO:0018065	protein-cofactor linkage(GO:0018065)
1.3	5.3	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.3	6.6	GO:0051026	chiasma assembly(GO:0051026)
1.3	4.0	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
1.3	4.0	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
1.3	2.6	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
1.3	1.3	GO:0002190	cap-independent translational initiation(GO:0002190)
1.3	6.6	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
1.3	6.6	GO:0042026	protein refolding(GO:0042026)
1.3	1.3	GO:0044774	mitotic DNA integrity checkpoint(GO:0044774)
1.3	1.3	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
1.3	1.3	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
1.3	11.8	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
1.3	6.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
1.3	1.3	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235)
1.3	3.9	GO:0016264	gap junction assembly(GO:0016264)
1.3	7.8	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
1.3	20.8	GO:1904029	regulation of cyclin-dependent protein kinase activity(GO:1904029)
1.3	42.9	GO:0006611	protein export from nucleus(GO:0006611)
1.3	23.4	GO:0033048	negative regulation of mitotic sister chromatid segregation(GO:0033048)
1.3	37.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
1.3	2.6	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
1.3	2.6	GO:0006116	NADH oxidation(GO:0006116)
1.3	2.6	GO:0018022	peptidyl-lysine methylation(GO:0018022)
1.3	2.6	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
1.3	20.5	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.3	3.8	GO:1901889	negative regulation of cell junction assembly(GO:1901889)
1.3	1.3	GO:0071450	cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
1.3	1.3	GO:0051036	regulation of endosome size(GO:0051036)
1.3	2.5	GO:0075525	viral translational termination-reinitiation(GO:0075525)
1.3	2.5	GO:0034214	protein hexamerization(GO:0034214)
1.3	5.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
1.3	3.8	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.3	3.8	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
1.3	3.8	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
1.3	2.5	GO:0015793	glycerol transport(GO:0015793)
1.3	6.3	GO:0032099	negative regulation of appetite(GO:0032099)
1.3	1.3	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
1.3	3.8	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
1.3	3.8	GO:0010387	COP9 signalosome assembly(GO:0010387)
1.3	1.3	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
1.3	3.8	GO:0008089	anterograde axonal transport(GO:0008089)
1.3	12.5	GO:0031648	protein destabilization(GO:0031648)
1.3	3.8	GO:0033572	transferrin transport(GO:0033572)
1.2	3.7	GO:0035405	histone-threonine phosphorylation(GO:0035405)
1.2	6.2	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
1.2	2.5	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
1.2	6.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.2	36.0	GO:0007030	Golgi organization(GO:0007030)
1.2	1.2	GO:0016572	histone phosphorylation(GO:0016572)
1.2	32.2	GO:0006749	glutathione metabolic process(GO:0006749)
1.2	2.5	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.2	14.9	GO:0016925	protein sumoylation(GO:0016925)
1.2	4.9	GO:1902018	negative regulation of cilium assembly(GO:1902018)
1.2	2.5	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.2	12.3	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
1.2	9.8	GO:0001893	maternal placenta development(GO:0001893)
1.2	6.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.2	3.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
1.2	3.7	GO:0051127	positive regulation of actin nucleation(GO:0051127)
1.2	9.7	GO:0007097	nuclear migration(GO:0007097)
1.2	6.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
1.2	1.2	GO:0002679	respiratory burst involved in defense response(GO:0002679)
1.2	1.2	GO:0051799	negative regulation of hair follicle development(GO:0051799)
1.2	2.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
1.2	7.3	GO:0006013	mannose metabolic process(GO:0006013)
1.2	2.4	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)
1.2	4.8	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
1.2	7.2	GO:0010664	negative regulation of striated muscle cell apoptotic process(GO:0010664)
1.2	1.2	GO:0006106	fumarate metabolic process(GO:0006106)
1.2	3.6	GO:0006907	pinocytosis(GO:0006907)
1.2	2.4	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
1.2	22.7	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
1.2	4.8	GO:1902414	protein localization to cell junction(GO:1902414)
1.2	6.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
1.2	1.2	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
1.2	4.8	GO:2001198	regulation of dendritic cell differentiation(GO:2001198) negative regulation of dendritic cell differentiation(GO:2001199)
1.2	9.5	GO:0072520	seminiferous tubule development(GO:0072520)
1.2	2.4	GO:0060920	cardiac pacemaker cell differentiation(GO:0060920) sinoatrial node cell differentiation(GO:0060921)
1.2	1.2	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
1.2	20.1	GO:0051865	protein autoubiquitination(GO:0051865)
1.2	13.0	GO:0051568	histone H3-K4 methylation(GO:0051568)
1.2	3.5	GO:0031054	pre-miRNA processing(GO:0031054)
1.2	1.2	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
1.2	5.9	GO:0032310	prostaglandin secretion(GO:0032310)
1.2	4.7	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
1.2	2.4	GO:0090435	protein localization to nuclear envelope(GO:0090435)
1.2	17.6	GO:0051310	metaphase plate congression(GO:0051310)
1.2	5.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.2	2.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.2	2.3	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
1.2	2.3	GO:0046174	polyol catabolic process(GO:0046174)
1.2	1.2	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
1.2	2.3	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
1.2	2.3	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
1.2	1.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.2	5.8	GO:0034198	cellular response to amino acid starvation(GO:0034198)
1.1	9.2	GO:0009303	rRNA transcription(GO:0009303)
1.1	4.6	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.1	48.0	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
1.1	1.1	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
1.1	2.3	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
1.1	3.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) late endosome to vacuole transport(GO:0045324)
1.1	18.2	GO:0051168	nuclear export(GO:0051168)
1.1	3.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
1.1	9.0	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
1.1	2.2	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
1.1	6.7	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
1.1	2.2	GO:0002892	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
1.1	11.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
1.1	2.2	GO:0045047	protein targeting to ER(GO:0045047)
1.1	3.3	GO:0009992	cellular water homeostasis(GO:0009992)
1.1	2.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
1.1	3.3	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.1	7.7	GO:0046039	GTP metabolic process(GO:0046039)
1.1	1.1	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.1	5.5	GO:0042448	progesterone metabolic process(GO:0042448)
1.1	12.0	GO:0060612	adipose tissue development(GO:0060612)
1.1	6.6	GO:0055090	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
1.1	2.2	GO:0051255	spindle midzone assembly(GO:0051255)
1.1	20.6	GO:0032465	regulation of cytokinesis(GO:0032465)
1.1	3.2	GO:0007028	cytoplasm organization(GO:0007028)
1.1	1.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
1.1	10.8	GO:1901739	regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
1.1	4.3	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
1.1	5.4	GO:0010829	negative regulation of glucose transport(GO:0010829)
1.1	2.1	GO:0040016	embryonic cleavage(GO:0040016)
1.1	3.2	GO:0010884	positive regulation of lipid storage(GO:0010884)
1.1	1.1	GO:0048382	mesendoderm development(GO:0048382)
1.1	1.1	GO:0051775	response to redox state(GO:0051775)
1.1	3.2	GO:0060155	platelet dense granule organization(GO:0060155)
1.1	1.1	GO:0043101	purine-containing compound salvage(GO:0043101)
1.1	3.2	GO:0036119	response to platelet-derived growth factor(GO:0036119)
1.1	2.1	GO:0070914	UV-damage excision repair(GO:0070914)
1.1	2.1	GO:0048143	astrocyte activation(GO:0048143)
1.1	41.2	GO:0051028	mRNA transport(GO:0051028)
1.1	10.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.1	4.2	GO:0015670	carbon dioxide transport(GO:0015670)
1.1	4.2	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
1.1	1.1	GO:0042891	antibiotic transport(GO:0042891)
1.0	8.4	GO:0006278	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
1.0	3.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
1.0	8.3	GO:0051014	actin filament severing(GO:0051014)
1.0	2.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
1.0	5.2	GO:2000351	regulation of endothelial cell apoptotic process(GO:2000351)
1.0	1.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
1.0	8.3	GO:0000469	cleavage involved in rRNA processing(GO:0000469)
1.0	3.1	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
1.0	2.1	GO:0070199	establishment of protein localization to chromosome(GO:0070199)
1.0	2.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
1.0	9.3	GO:0070265	necrotic cell death(GO:0070265)
1.0	1.0	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
1.0	7.2	GO:0043248	proteasome assembly(GO:0043248)
1.0	3.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
1.0	5.1	GO:0030261	chromosome condensation(GO:0030261)
1.0	6.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
1.0	5.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
1.0	20.5	GO:0016126	sterol biosynthetic process(GO:0016126)
1.0	7.2	GO:0097345	mitochondrial outer membrane permeabilization(GO:0097345)
1.0	2.0	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
1.0	3.0	GO:0016554	cytidine to uridine editing(GO:0016554)
1.0	2.0	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.0	3.0	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
1.0	10.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
1.0	12.2	GO:0030149	sphingolipid catabolic process(GO:0030149)
1.0	4.0	GO:0060352	cell adhesion molecule production(GO:0060352)
1.0	29.3	GO:0045454	cell redox homeostasis(GO:0045454)
1.0	1.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
1.0	1.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
1.0	6.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.0	1.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
1.0	1.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
1.0	1.0	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
1.0	30.8	GO:0031338	regulation of vesicle fusion(GO:0031338)
1.0	2.0	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
1.0	1.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
1.0	2.0	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
1.0	1.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
1.0	2.0	GO:0042574	retinal metabolic process(GO:0042574)
1.0	2.0	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
1.0	1.0	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
1.0	3.9	GO:0016576	histone dephosphorylation(GO:0016576)
1.0	39.3	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
1.0	1.0	GO:0031047	gene silencing by RNA(GO:0031047)
1.0	2.0	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
1.0	1.0	GO:0031627	telomeric loop formation(GO:0031627)
1.0	7.8	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
1.0	23.5	GO:0042073	intraciliary transport(GO:0042073)
1.0	2.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
1.0	14.6	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
1.0	9.8	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
1.0	4.9	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
1.0	3.9	GO:0019336	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.0	9.7	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
1.0	8.7	GO:0006691	leukotriene metabolic process(GO:0006691)
1.0	2.9	GO:1903999	negative regulation of eating behavior(GO:1903999)
1.0	1.0	GO:0006776	vitamin A metabolic process(GO:0006776)
1.0	2.9	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
1.0	6.8	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.0	1.0	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.0	6.7	GO:0007379	segment specification(GO:0007379)
1.0	5.8	GO:0002227	innate immune response in mucosa(GO:0002227)
1.0	5.7	GO:0002467	germinal center formation(GO:0002467)
1.0	1.9	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
1.0	1.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.9	1.9	GO:0009299	mRNA transcription(GO:0009299)
0.9	8.5	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.9	3.8	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.9	3.8	GO:0045738	negative regulation of DNA repair(GO:0045738)
0.9	0.9	GO:0018126	protein hydroxylation(GO:0018126)
0.9	5.6	GO:0000338	protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.9	0.9	GO:0006577	amino-acid betaine metabolic process(GO:0006577)
0.9	6.5	GO:0034453	microtubule anchoring(GO:0034453)
0.9	0.9	GO:0072527	pyrimidine-containing compound metabolic process(GO:0072527)
0.9	5.6	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.9	19.5	GO:0071277	cellular response to calcium ion(GO:0071277)
0.9	1.9	GO:0032482	Rab protein signal transduction(GO:0032482)
0.9	2.8	GO:0019348	dolichol metabolic process(GO:0019348)
0.9	70.4	GO:0016568	chromatin modification(GO:0016568)
0.9	4.6	GO:0048520	positive regulation of behavior(GO:0048520)
0.9	7.4	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.9	35.1	GO:0051297	centrosome organization(GO:0051297)
0.9	1.8	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.9	11.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.9	3.7	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.9	1.8	GO:0031033	myosin filament organization(GO:0031033)
0.9	12.0	GO:0071901	negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.9	1.8	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.9	5.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.9	11.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.9	2.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.9	3.7	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
0.9	1.8	GO:0008228	opsonization(GO:0008228)
0.9	1.8	GO:0051985	negative regulation of chromosome segregation(GO:0051985)
0.9	1.8	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.9	5.5	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.9	10.0	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.9	6.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.9	0.9	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.9	2.7	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.9	19.0	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.9	2.7	GO:0046131	pyrimidine ribonucleoside metabolic process(GO:0046131)
0.9	1.8	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.9	0.9	GO:0070189	kynurenine metabolic process(GO:0070189)
0.9	2.7	GO:0006903	vesicle targeting(GO:0006903)
0.9	2.7	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.9	20.7	GO:0006641	triglyceride metabolic process(GO:0006641)
0.9	1.8	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.9	9.0	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9	8.1	GO:0043620	regulation of DNA-templated transcription in response to stress(GO:0043620)
0.9	0.9	GO:0044803	multi-organism membrane organization(GO:0044803)
0.9	12.5	GO:0006284	base-excision repair(GO:0006284)
0.9	1.8	GO:0010225	response to UV-C(GO:0010225)
0.9	0.9	GO:0032105	negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.9	42.2	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.9	0.9	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.9	7.0	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)
0.9	0.9	GO:0044381	glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.9	0.9	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.9	0.9	GO:0032095	regulation of response to food(GO:0032095)
0.9	46.8	GO:0006457	protein folding(GO:0006457)
0.9	1.7	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.9	2.6	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.9	1.7	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.9	4.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.9	3.4	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.8	0.8	GO:0030953	astral microtubule organization(GO:0030953)
0.8	23.7	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.8	18.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.8	3.4	GO:0032570	response to progesterone(GO:0032570)
0.8	3.4	GO:0046415	urate metabolic process(GO:0046415)
0.8	8.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.8	3.3	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.8	1.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8	25.6	GO:0032543	mitochondrial translation(GO:0032543)
0.8	8.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.8	12.3	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.8	0.8	GO:0001812	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) positive regulation of type I hypersensitivity(GO:0001812)
0.8	7.3	GO:0007032	endosome organization(GO:0007032)
0.8	0.8	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.8	4.0	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.8	0.8	GO:0070831	basement membrane assembly(GO:0070831)
0.8	7.3	GO:0035456	response to interferon-beta(GO:0035456)
0.8	5.6	GO:0016926	protein desumoylation(GO:0016926)
0.8	17.7	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.8	1.6	GO:0031023	microtubule organizing center organization(GO:0031023)
0.8	1.6	GO:0042126	nitrate metabolic process(GO:0042126)
0.8	4.8	GO:0051782	negative regulation of cell division(GO:0051782)
0.8	2.4	GO:0032790	ribosome disassembly(GO:0032790)
0.8	7.9	GO:0035455	response to interferon-alpha(GO:0035455)
0.8	0.8	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.8	2.4	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.8	3.1	GO:0055094	response to lipoprotein particle(GO:0055094)
0.8	4.7	GO:0010507	negative regulation of autophagy(GO:0010507)
0.8	6.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.8	4.7	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.8	3.1	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.8	2.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.8	2.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.8	0.8	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.8	3.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.8	1.5	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.8	4.6	GO:0071361	cellular response to ethanol(GO:0071361)
0.8	6.8	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.8	3.0	GO:0015871	choline transport(GO:0015871)
0.8	8.3	GO:1902808	positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.8	9.0	GO:0050821	protein stabilization(GO:0050821)
0.7	0.7	GO:0002724	T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724)
0.7	1.5	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.7	18.5	GO:0055088	lipid homeostasis(GO:0055088)
0.7	3.7	GO:0021535	cell migration in hindbrain(GO:0021535)
0.7	1.5	GO:0006553	lysine metabolic process(GO:0006553)
0.7	33.9	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
0.7	2.9	GO:0048193	Golgi vesicle transport(GO:0048193)
0.7	5.1	GO:0032438	melanosome organization(GO:0032438)
0.7	4.4	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.7	2.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.7	8.0	GO:0014850	response to muscle activity(GO:0014850)
0.7	0.7	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.7	17.3	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.7	2.9	GO:0042989	sequestering of actin monomers(GO:0042989)
0.7	10.1	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.7	2.2	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.7	2.9	GO:0036233	glycine import(GO:0036233)
0.7	1.4	GO:0072537	fibroblast activation(GO:0072537)
0.7	0.7	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.7	2.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.7	2.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.7	0.7	GO:0031052	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.7	3.5	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.7	2.8	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.7	4.2	GO:0051905	establishment of pigment granule localization(GO:0051905)
0.7	0.7	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.7	1.4	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.7	14.1	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.7	2.1	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.7	14.7	GO:0018345	protein palmitoylation(GO:0018345)
0.7	4.9	GO:0033344	cholesterol efflux(GO:0033344)
0.7	2.1	GO:0000012	single strand break repair(GO:0000012)
0.7	6.3	GO:1902850	mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.7	2.8	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.7	0.7	GO:1903543	regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.7	0.7	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.7	8.3	GO:0046889	positive regulation of lipid biosynthetic process(GO:0046889)
0.7	1.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.7	2.8	GO:0000154	rRNA modification(GO:0000154)
0.7	2.1	GO:0080154	regulation of fertilization(GO:0080154)
0.7	2.1	GO:0015888	thiamine transport(GO:0015888)
0.7	13.0	GO:0006986	response to unfolded protein(GO:0006986)
0.7	0.7	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.7	4.1	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.7	2.0	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.7	4.1	GO:0060009	Sertoli cell development(GO:0060009)
0.7	12.1	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7	4.7	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.7	0.7	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.7	14.0	GO:0006829	zinc II ion transport(GO:0006829)
0.7	1.3	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.7	1.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.7	1.3	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.7	1.3	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.7	7.9	GO:0006308	DNA catabolic process(GO:0006308)
0.7	0.7	GO:0015791	polyol transport(GO:0015791)
0.6	2.6	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.6	0.6	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.6	1.3	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.6	18.7	GO:0043039	tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.6	7.6	GO:0006730	one-carbon metabolic process(GO:0006730)
0.6	1.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.6	22.8	GO:1903955	positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.6	2.5	GO:0009642	response to light intensity(GO:0009642)
0.6	2.5	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6	0.6	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.6	0.6	GO:0010165	response to X-ray(GO:0010165)
0.6	3.1	GO:0006414	translational elongation(GO:0006414)
0.6	0.6	GO:0040033	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.6	17.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.6	10.6	GO:0005977	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.6	1.2	GO:1901068	guanosine-containing compound metabolic process(GO:1901068)
0.6	12.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.6	0.6	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.6	0.6	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.6	3.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.6	1.9	GO:0052055	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.6	1.9	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.6	0.6	GO:1902221	L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.6	1.8	GO:0006768	biotin metabolic process(GO:0006768)
0.6	0.6	GO:1903012	positive regulation of bone development(GO:1903012)
0.6	1.8	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.6	6.7	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.6	13.4	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.6	0.6	GO:0050667	homocysteine metabolic process(GO:0050667)
0.6	0.6	GO:0045112	integrin biosynthetic process(GO:0045112)
0.6	0.6	GO:0097066	response to thyroid hormone(GO:0097066)
0.6	0.6	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.6	0.6	GO:0044027	maintenance of DNA methylation(GO:0010216) DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.6	6.0	GO:1901998	toxin transport(GO:1901998)
0.6	1.8	GO:0006839	mitochondrial transport(GO:0006839)
0.6	3.0	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.6	7.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6	3.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.6	10.1	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.6	0.6	GO:0019530	taurine metabolic process(GO:0019530)
0.6	1.2	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.6	0.6	GO:0071332	response to fructose(GO:0009750) cellular response to fructose stimulus(GO:0071332)
0.6	4.1	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.6	1.2	GO:0000723	telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.6	6.4	GO:0042832	defense response to protozoan(GO:0042832)
0.6	2.9	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.6	1.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.6	0.6	GO:0010459	negative regulation of heart rate(GO:0010459)
0.6	1.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.6	4.0	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.6	0.6	GO:1903364	positive regulation of cellular protein catabolic process(GO:1903364)
0.6	2.3	GO:0015825	L-serine transport(GO:0015825)
0.6	1.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.6	2.8	GO:0007603	phototransduction, visible light(GO:0007603)
0.6	2.8	GO:0007031	peroxisome organization(GO:0007031)
0.6	0.6	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.6	1.7	GO:0006448	regulation of translational elongation(GO:0006448)
0.6	10.6	GO:0002181	cytoplasmic translation(GO:0002181)
0.6	1.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.6	4.5	GO:0071800	podosome assembly(GO:0071800)
0.6	2.8	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.6	1.1	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.6	0.6	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.5	4.4	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.5	10.4	GO:0006446	regulation of translational initiation(GO:0006446)
0.5	2.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.5	0.5	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.5	1.1	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.5	1.1	GO:0002215	defense response to nematode(GO:0002215)
0.5	2.2	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.5	16.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323)
0.5	1.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.5	1.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.5	2.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5	1.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.5	2.1	GO:0033013	tetrapyrrole metabolic process(GO:0033013)
0.5	0.5	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.5	67.3	GO:0008380	RNA splicing(GO:0008380)
0.5	9.3	GO:0006413	translational initiation(GO:0006413)
0.5	6.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.5	0.5	GO:0009445	putrescine metabolic process(GO:0009445)
0.5	2.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.5	3.6	GO:0010498	proteasomal protein catabolic process(GO:0010498)
0.5	0.5	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.5	2.5	GO:0001556	oocyte maturation(GO:0001556)
0.5	1.5	GO:0006525	arginine metabolic process(GO:0006525)
0.5	2.5	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.5	2.0	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.5	0.5	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.5	0.5	GO:1904238	pericyte cell differentiation(GO:1904238)
0.5	1.5	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.5	1.5	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.5	1.0	GO:0019395	fatty acid oxidation(GO:0019395)
0.5	1.5	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.5	9.3	GO:0019835	cytolysis(GO:0019835)
0.5	1.5	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5	3.9	GO:0072350	tricarboxylic acid metabolic process(GO:0072350)
0.5	3.4	GO:0070193	synaptonemal complex organization(GO:0070193)
0.5	24.3	GO:0008033	tRNA processing(GO:0008033)
0.5	0.5	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.5	6.8	GO:0006491	N-glycan processing(GO:0006491)
0.5	1.4	GO:0000272	polysaccharide catabolic process(GO:0000272)
0.5	2.9	GO:1901224	positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.5	1.4	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.5	0.9	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.5	3.3	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.5	2.4	GO:0042756	drinking behavior(GO:0042756)
0.5	59.1	GO:0016567	protein ubiquitination(GO:0016567)
0.5	3.7	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
0.5	0.5	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.5	0.9	GO:0006833	water transport(GO:0006833)
0.5	0.5	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.5	3.2	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.5	0.9	GO:0019377	glycolipid catabolic process(GO:0019377)
0.5	0.5	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.5	5.9	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.5	0.9	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.5	0.5	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.4	0.4	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.4	0.4	GO:2000573	positive regulation of DNA biosynthetic process(GO:2000573)
0.4	2.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.4	1.3	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.4	8.8	GO:0006974	cellular response to DNA damage stimulus(GO:0006974)
0.4	6.6	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.4	0.4	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.4	0.9	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.4	0.4	GO:0009946	proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
0.4	0.4	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.4	0.9	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.4	0.4	GO:0051236	establishment of RNA localization(GO:0051236)
0.4	1.7	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.4	2.1	GO:0007062	sister chromatid cohesion(GO:0007062)
0.4	2.9	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.4	5.0	GO:0000045	autophagosome assembly(GO:0000045)
0.4	1.3	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.4	1.7	GO:0036297	interstrand cross-link repair(GO:0036297)
0.4	5.4	GO:0000266	mitochondrial fission(GO:0000266)
0.4	12.4	GO:0006970	response to osmotic stress(GO:0006970)
0.4	1.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4	0.4	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.4	6.8	GO:0006006	glucose metabolic process(GO:0006006)
0.4	4.8	GO:0007052	mitotic spindle organization(GO:0007052)
0.4	0.8	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.4	2.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.4	1.2	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.4	0.8	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4	1.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4	0.4	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.4	0.8	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.4	2.3	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.4	1.9	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.4	3.8	GO:0046364	monosaccharide biosynthetic process(GO:0046364)
0.4	0.4	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.4	0.4	GO:0007228	signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
0.4	1.1	GO:0009404	toxin metabolic process(GO:0009404)
0.4	0.7	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.4	5.4	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.4	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.4	1.1	GO:0014823	response to activity(GO:0014823)
0.4	1.1	GO:0031647	regulation of protein stability(GO:0031647)
0.4	1.1	GO:0015671	oxygen transport(GO:0015671)
0.4	0.4	GO:0033280	response to vitamin D(GO:0033280)
0.4	1.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.4	1.4	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.4	3.2	GO:0008209	androgen metabolic process(GO:0008209)
0.4	0.4	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.3	0.3	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.3	0.7	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.3	2.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.3	2.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.3	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.3	0.3	GO:1990542	mitochondrial transmembrane transport(GO:1990542)
0.3	2.7	GO:0048246	macrophage chemotaxis(GO:0048246)
0.3	0.7	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.3	1.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.3	1.0	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.3	1.0	GO:0010039	response to iron ion(GO:0010039)
0.3	0.7	GO:0032446	protein modification by small protein conjugation(GO:0032446)
0.3	0.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.3	0.7	GO:0006401	RNA catabolic process(GO:0006401)
0.3	2.0	GO:0035608	protein deglutamylation(GO:0035608)
0.3	3.9	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.3	7.8	GO:0007059	chromosome segregation(GO:0007059)
0.3	1.0	GO:0030225	macrophage differentiation(GO:0030225)
0.3	6.5	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.3	1.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	0.3	GO:0097709	wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.3	0.3	GO:0034381	plasma lipoprotein particle clearance(GO:0034381)
0.3	0.6	GO:0055119	relaxation of cardiac muscle(GO:0055119)
0.3	1.0	GO:0019321	pentose metabolic process(GO:0019321)
0.3	0.6	GO:0042255	ribosome assembly(GO:0042255)
0.3	0.3	GO:0032494	response to peptidoglycan(GO:0032494)
0.3	1.5	GO:0070995	NADPH oxidation(GO:0070995)
0.3	0.3	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.3	0.9	GO:2000378	negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.3	0.9	GO:2000209	regulation of anoikis(GO:2000209)
0.3	0.3	GO:0061009	common bile duct development(GO:0061009)
0.3	2.4	GO:0019079	viral genome replication(GO:0019079)
0.3	1.2	GO:0006020	inositol metabolic process(GO:0006020)
0.3	0.3	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.3	0.6	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3	1.8	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.3	1.8	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
0.3	1.8	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.3	1.2	GO:0042990	regulation of transcription factor import into nucleus(GO:0042990)
0.3	0.9	GO:0046782	regulation of viral transcription(GO:0046782)
0.3	14.2	GO:0032259	methylation(GO:0032259)
0.3	1.2	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.3	0.3	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.3	2.3	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.3	0.3	GO:0006289	nucleotide-excision repair(GO:0006289)
0.3	1.4	GO:0070269	pyroptosis(GO:0070269)
0.3	0.3	GO:0006545	glycine biosynthetic process(GO:0006545)
0.3	1.4	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.3	0.3	GO:0033762	response to glucagon(GO:0033762)
0.3	3.1	GO:0034308	primary alcohol metabolic process(GO:0034308)
0.3	0.8	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.3	0.6	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.3	1.4	GO:0046677	response to antibiotic(GO:0046677)
0.3	0.3	GO:0071107	response to parathyroid hormone(GO:0071107)
0.3	0.3	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.3	0.5	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.3	0.3	GO:0000255	allantoin metabolic process(GO:0000255)
0.3	1.6	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3	2.3	GO:0042254	ribosome biogenesis(GO:0042254)
0.3	0.3	GO:0005984	disaccharide metabolic process(GO:0005984)
0.3	3.3	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.3	2.3	GO:0071875	adrenergic receptor signaling pathway(GO:0071875)
0.3	3.1	GO:0006801	superoxide metabolic process(GO:0006801)
0.3	0.8	GO:0009629	response to gravity(GO:0009629)
0.2	2.2	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.2	1.0	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2	0.2	GO:0043276	anoikis(GO:0043276)
0.2	39.9	GO:0043043	peptide biosynthetic process(GO:0043043)
0.2	0.2	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2	0.7	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.2	1.0	GO:0034976	response to endoplasmic reticulum stress(GO:0034976)
0.2	1.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.2	0.9	GO:0006968	cellular defense response(GO:0006968)
0.2	0.2	GO:0033034	positive regulation of myeloid cell apoptotic process(GO:0033034)
0.2	1.6	GO:0030888	regulation of B cell proliferation(GO:0030888)
0.2	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.2	0.7	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
0.2	0.7	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.2	0.4	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.2	0.4	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.2	14.2	GO:0051603	proteolysis involved in cellular protein catabolic process(GO:0051603)
0.2	1.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	0.2	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2	0.6	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.2	1.5	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.2	11.9	GO:0006281	DNA repair(GO:0006281)
0.2	0.8	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.2	1.6	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.2	13.2	GO:0071222	cellular response to lipopolysaccharide(GO:0071222)
0.2	0.4	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.2	0.4	GO:0030916	otic vesicle formation(GO:0030916)
0.2	0.2	GO:2000514	regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370) regulation of CD4-positive, alpha-beta T cell activation(GO:2000514)
0.2	0.6	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.2	0.2	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.2	0.8	GO:0044144	regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.2	1.5	GO:0017144	drug metabolic process(GO:0017144)
0.2	0.4	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2	0.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2	0.4	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	0.2	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.2	0.2	GO:0019692	2'-deoxyribonucleotide metabolic process(GO:0009394) deoxyribose phosphate metabolic process(GO:0019692)
0.2	4.3	GO:0016071	mRNA metabolic process(GO:0016071)
0.2	0.6	GO:0030321	transepithelial chloride transport(GO:0030321)
0.2	0.6	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.2	0.2	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.2	0.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	0.7	GO:0006959	humoral immune response(GO:0006959)
0.2	3.1	GO:0048240	sperm capacitation(GO:0048240)
0.2	0.2	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.2	0.4	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2	0.5	GO:0002553	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2	1.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.2	GO:0072126	positive regulation of glomerular mesangial cell proliferation(GO:0072126)
0.2	0.2	GO:0009124	nucleoside monophosphate biosynthetic process(GO:0009124)
0.2	0.7	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.2	0.7	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2	0.2	GO:0000956	nuclear-transcribed mRNA catabolic process(GO:0000956)
0.2	0.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.2	0.3	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2	0.5	GO:0007127	meiosis I(GO:0007127)
0.2	1.6	GO:0031123	RNA 3'-end processing(GO:0031123)
0.2	1.0	GO:0051205	protein insertion into membrane(GO:0051205)
0.2	0.2	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.2	1.9	GO:0070527	platelet aggregation(GO:0070527)
0.2	1.5	GO:0048286	lung alveolus development(GO:0048286)
0.2	0.2	GO:0045023	G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316)
0.2	0.2	GO:0042506	tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.1	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.1	0.9	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	1.2	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.1	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.1	0.1	GO:0048535	lymph node development(GO:0048535)
0.1	0.3	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.1	1.5	GO:0070647	protein modification by small protein conjugation or removal(GO:0070647)
0.1	0.3	GO:0009109	coenzyme catabolic process(GO:0009109)
0.1	0.1	GO:0009164	nucleoside catabolic process(GO:0009164)
0.1	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.1	1.0	GO:0097352	autophagosome maturation(GO:0097352)
0.1	0.6	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.1	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.1	0.7	GO:0032060	bleb assembly(GO:0032060)
0.1	0.7	GO:0097194	execution phase of apoptosis(GO:0097194)
0.1	0.1	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.1	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	0.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	1.7	GO:0006953	acute-phase response(GO:0006953)
0.1	0.8	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.1	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	1.0	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1	3.9	GO:0006396	RNA processing(GO:0006396)
0.1	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.1	0.4	GO:0030033	microvillus assembly(GO:0030033)
0.1	0.1	GO:0007567	parturition(GO:0007567)
0.1	0.4	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.1	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	0.2	GO:0032620	interleukin-17 production(GO:0032620)
0.1	0.1	GO:0060295	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	0.1	GO:0032370	positive regulation of lipid transport(GO:0032370)
0.1	0.4	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
0.1	0.2	GO:0042534	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.1	0.1	GO:0002825	regulation of T-helper 1 type immune response(GO:0002825)
0.1	0.2	GO:0006475	internal protein amino acid acetylation(GO:0006475)
0.1	0.2	GO:0097531	mast cell migration(GO:0097531)
0.1	0.9	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.1	1.3	GO:0072348	sulfur compound transport(GO:0072348)
0.1	0.1	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.1	15.1	GO:0007283	spermatogenesis(GO:0007283)
0.1	0.2	GO:0006817	phosphate ion transport(GO:0006817)
0.1	0.1	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.1	0.1	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.1	0.1	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.1	0.1	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.1	0.3	GO:0048541	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.1	0.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1	0.1	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1	0.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.1	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	2.0	GO:0006956	complement activation(GO:0006956)
0.1	0.1	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.1	0.5	GO:0030101	natural killer cell activation(GO:0030101)
0.1	0.1	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.1	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1	0.1	GO:0051132	NK T cell activation(GO:0051132)
0.1	1.3	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.1	0.2	GO:0000959	mitochondrial RNA metabolic process(GO:0000959)
0.1	2.4	GO:0050912	detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1	0.1	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.1	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:0015931	nucleobase-containing compound transport(GO:0015931)
0.1	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.1	GO:0002583	regulation of antigen processing and presentation of peptide antigen(GO:0002583)
0.1	0.2	GO:0002920	regulation of humoral immune response(GO:0002920)
0.0	0.1	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0	0.0	GO:0035898	parathyroid hormone secretion(GO:0035898)
0.0	2.7	GO:0006631	fatty acid metabolic process(GO:0006631)
0.0	0.2	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.0	0.0	GO:0001562	response to protozoan(GO:0001562)
0.0	0.1	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0072672	neutrophil extravasation(GO:0072672)
0.0	0.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	0.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	1.3	GO:0042742	defense response to bacterium(GO:0042742)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.0	GO:1900225	regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0006473	protein acetylation(GO:0006473)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.8	39.3	GO:0072487	MSL complex(GO:0072487)
9.8	29.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
8.9	26.6	GO:0005667	transcription factor complex(GO:0005667)
7.6	37.8	GO:0016461	unconventional myosin complex(GO:0016461)
7.3	58.5	GO:0001650	fibrillar center(GO:0001650)
7.2	21.5	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
6.9	27.6	GO:0097524	sperm plasma membrane(GO:0097524)
6.8	27.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
6.5	26.1	GO:0005642	annulate lamellae(GO:0005642)
6.5	45.2	GO:0005677	chromatin silencing complex(GO:0005677)
6.3	19.0	GO:0031094	platelet dense tubular network(GO:0031094)
6.3	25.1	GO:0071141	SMAD protein complex(GO:0071141)
6.0	18.1	GO:0043293	apoptosome(GO:0043293)
6.0	18.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
5.8	29.2	GO:0005638	lamin filament(GO:0005638)
5.6	22.3	GO:0030121	AP-1 adaptor complex(GO:0030121)
5.5	32.8	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
5.4	21.7	GO:0005955	calcineurin complex(GO:0005955)
5.3	10.6	GO:0097451	glial limiting end-foot(GO:0097451)
5.3	15.8	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
5.2	5.2	GO:1990075	periciliary membrane compartment(GO:1990075)
5.2	51.8	GO:0031010	ISWI-type complex(GO:0031010)
5.2	61.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
5.1	20.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
5.1	61.3	GO:0071564	npBAF complex(GO:0071564)
5.0	30.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
5.0	34.9	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
5.0	15.0	GO:0097443	sorting endosome(GO:0097443)
5.0	14.9	GO:0036488	CHOP-C/EBP complex(GO:0036488)
4.9	19.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
4.8	14.4	GO:0000811	GINS complex(GO:0000811)
4.7	19.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
4.7	23.3	GO:0042824	MHC class I peptide loading complex(GO:0042824)
4.6	18.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
4.6	150.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
4.4	44.2	GO:0016580	Sin3 complex(GO:0016580)
4.4	202.2	GO:0000118	histone deacetylase complex(GO:0000118)
4.4	13.1	GO:0031523	Myb complex(GO:0031523)
4.4	13.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
4.3	64.9	GO:0000421	autophagosome membrane(GO:0000421)
4.3	38.7	GO:0000124	SAGA complex(GO:0000124)
4.3	12.9	GO:1990462	omegasome(GO:1990462)
4.3	17.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
4.2	12.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
4.2	16.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
4.2	25.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
4.2	20.9	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
4.1	61.6	GO:0030014	CCR4-NOT complex(GO:0030014)
4.1	12.3	GO:0005745	m-AAA complex(GO:0005745)
4.1	12.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
4.1	40.5	GO:0090544	BAF-type complex(GO:0090544)
3.9	11.7	GO:0031417	NatC complex(GO:0031417)
3.9	101.6	GO:0031519	PcG protein complex(GO:0031519)
3.9	15.4	GO:0044326	dendritic spine neck(GO:0044326)
3.9	27.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
3.8	15.3	GO:0097431	mitotic spindle pole(GO:0097431)
3.8	45.6	GO:0030914	STAGA complex(GO:0030914)
3.7	11.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
3.6	54.2	GO:0071004	U2-type prespliceosome(GO:0071004)
3.5	3.5	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
3.5	6.9	GO:0070688	MLL5-L complex(GO:0070688)
3.5	72.5	GO:0035145	exon-exon junction complex(GO:0035145)
3.4	37.7	GO:0032039	integrator complex(GO:0032039)
3.4	33.6	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
3.4	3.4	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
3.3	16.7	GO:0000235	astral microtubule(GO:0000235)
3.3	10.0	GO:0044530	supraspliceosomal complex(GO:0044530)
3.3	39.8	GO:0010369	chromocenter(GO:0010369)
3.3	13.3	GO:0000805	X chromosome(GO:0000805)
3.3	9.9	GO:0097418	neurofibrillary tangle(GO:0097418)
3.3	13.2	GO:0030127	COPII vesicle coat(GO:0030127)
3.3	9.9	GO:0031084	BLOC-2 complex(GO:0031084)
3.2	16.1	GO:0033093	Weibel-Palade body(GO:0033093)
3.2	152.7	GO:0000123	histone acetyltransferase complex(GO:0000123)
3.1	25.2	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
3.1	15.7	GO:0005964	phosphorylase kinase complex(GO:0005964)
3.1	6.2	GO:0033269	internode region of axon(GO:0033269)
3.1	6.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
3.0	33.4	GO:0070938	contractile ring(GO:0070938)
3.0	15.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
3.0	21.0	GO:0031931	TORC1 complex(GO:0031931)
3.0	8.9	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
2.9	11.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
2.9	11.7	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
2.9	26.1	GO:0051286	cell tip(GO:0051286)
2.9	8.6	GO:0071817	MMXD complex(GO:0071817)
2.9	14.3	GO:0090543	Flemming body(GO:0090543)
2.8	25.6	GO:0034709	methylosome(GO:0034709)
2.8	8.5	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
2.8	47.8	GO:0005719	nuclear euchromatin(GO:0005719)
2.8	11.3	GO:0036449	microtubule minus-end(GO:0036449)
2.8	25.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
2.8	19.4	GO:0001939	female pronucleus(GO:0001939)
2.8	8.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
2.8	80.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
2.7	8.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
2.7	8.0	GO:0055087	Ski complex(GO:0055087)
2.6	13.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
2.6	23.6	GO:0031011	Ino80 complex(GO:0031011)
2.6	26.2	GO:0005721	pericentric heterochromatin(GO:0005721)
2.6	5.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
2.6	20.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
2.5	17.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
2.5	17.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
2.5	7.5	GO:0097452	GAIT complex(GO:0097452)
2.5	12.4	GO:0033503	HULC complex(GO:0033503)
2.5	19.8	GO:1990909	Wnt signalosome(GO:1990909)
2.5	9.9	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
2.5	7.4	GO:0042405	nuclear inclusion body(GO:0042405)
2.5	12.3	GO:0045120	pronucleus(GO:0045120)
2.5	9.8	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.4	7.3	GO:0097413	Lewy body(GO:0097413)
2.4	2.4	GO:0005687	U4 snRNP(GO:0005687)
2.4	9.5	GO:0035363	histone locus body(GO:0035363)
2.4	19.1	GO:1990023	mitotic spindle midzone(GO:1990023)
2.4	23.8	GO:0090533	cation-transporting ATPase complex(GO:0090533)
2.4	11.9	GO:0044294	dendritic growth cone(GO:0044294)
2.4	11.8	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.3	145.5	GO:0016363	nuclear matrix(GO:0016363)
2.3	37.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
2.3	7.0	GO:0097149	centralspindlin complex(GO:0097149)
2.3	34.9	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
2.3	127.3	GO:0016605	PML body(GO:0016605)
2.3	43.6	GO:0000786	nucleosome(GO:0000786)
2.3	9.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
2.3	2.3	GO:0005899	insulin receptor complex(GO:0005899)
2.3	11.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
2.3	15.8	GO:0061700	GATOR2 complex(GO:0061700)
2.2	6.7	GO:0071797	LUBAC complex(GO:0071797)
2.2	20.2	GO:0002116	semaphorin receptor complex(GO:0002116)
2.2	46.8	GO:0005680	anaphase-promoting complex(GO:0005680)
2.2	261.7	GO:0000790	nuclear chromatin(GO:0000790)
2.2	8.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
2.2	13.1	GO:0035748	myelin sheath abaxonal region(GO:0035748)
2.2	6.5	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
2.2	10.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.2	23.9	GO:0031616	spindle pole centrosome(GO:0031616)
2.2	28.2	GO:0031528	microvillus membrane(GO:0031528)
2.2	6.5	GO:0000322	storage vacuole(GO:0000322)
2.2	17.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
2.2	47.5	GO:0008023	transcription elongation factor complex(GO:0008023)
2.1	10.7	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
2.1	21.5	GO:0070852	cell body fiber(GO:0070852)
2.1	12.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.1	21.2	GO:0035631	CD40 receptor complex(GO:0035631)
2.1	10.6	GO:0061617	MICOS complex(GO:0061617)
2.1	8.4	GO:0000796	condensin complex(GO:0000796)
2.1	2.1	GO:0097427	microtubule bundle(GO:0097427)
2.1	12.6	GO:0044327	dendritic spine head(GO:0044327)
2.1	18.8	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
2.1	16.6	GO:0070652	HAUS complex(GO:0070652)
2.1	22.8	GO:0002199	zona pellucida receptor complex(GO:0002199)
2.1	64.0	GO:0016592	mediator complex(GO:0016592)
2.0	4.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
2.0	202.1	GO:0072562	blood microparticle(GO:0072562)
2.0	63.2	GO:0005876	spindle microtubule(GO:0005876)
2.0	109.3	GO:0000785	chromatin(GO:0000785)
2.0	64.8	GO:0017053	transcriptional repressor complex(GO:0017053)
2.0	22.2	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
2.0	6.0	GO:0089701	U2AF(GO:0089701)
2.0	6.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
2.0	52.2	GO:0008180	COP9 signalosome(GO:0008180)
2.0	28.1	GO:0001891	phagocytic cup(GO:0001891)
2.0	2.0	GO:0016939	kinesin II complex(GO:0016939)
2.0	27.9	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
2.0	35.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
2.0	9.9	GO:0097422	tubular endosome(GO:0097422)
2.0	6.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
2.0	7.9	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
2.0	5.9	GO:1990130	Iml1 complex(GO:1990130)
2.0	2.0	GO:0072686	mitotic spindle(GO:0072686)
2.0	3.9	GO:0031088	platelet dense granule membrane(GO:0031088)
2.0	3.9	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
2.0	23.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
2.0	21.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
2.0	11.7	GO:0031415	NatA complex(GO:0031415)
1.9	5.8	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
1.9	1.9	GO:0000439	core TFIIH complex(GO:0000439)
1.9	7.7	GO:0035749	myelin sheath adaxonal region(GO:0035749)
1.9	3.8	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.9	7.6	GO:1990111	spermatoproteasome complex(GO:1990111)
1.9	1.9	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
1.9	20.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
1.9	5.6	GO:0005652	nuclear lamina(GO:0005652)
1.9	11.2	GO:0097542	ciliary tip(GO:0097542)
1.9	9.3	GO:0042575	DNA polymerase complex(GO:0042575)
1.9	1.9	GO:0000346	transcription export complex(GO:0000346)
1.9	5.6	GO:0031595	nuclear proteasome complex(GO:0031595)
1.9	20.4	GO:0017119	Golgi transport complex(GO:0017119)
1.8	27.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
1.8	5.5	GO:0031932	TORC2 complex(GO:0031932)
1.8	5.4	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
1.8	7.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
1.8	23.1	GO:0000242	pericentriolar material(GO:0000242)
1.8	16.0	GO:0030894	replisome(GO:0030894)
1.8	19.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.7	7.0	GO:0046581	intercellular canaliculus(GO:0046581)
1.7	8.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.7	10.4	GO:0042587	glycogen granule(GO:0042587)
1.7	7.0	GO:0071203	WASH complex(GO:0071203)
1.7	27.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.7	59.0	GO:0045171	intercellular bridge(GO:0045171)
1.7	3.5	GO:0000814	ESCRT II complex(GO:0000814)
1.7	3.5	GO:0005879	axonemal microtubule(GO:0005879)
1.7	3.5	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.7	5.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
1.7	3.5	GO:0030125	clathrin vesicle coat(GO:0030125)
1.7	5.1	GO:0031262	Ndc80 complex(GO:0031262)
1.7	187.2	GO:0016604	nuclear body(GO:0016604)
1.7	10.2	GO:0031209	SCAR complex(GO:0031209)
1.7	5.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.7	54.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
1.7	6.7	GO:1990246	uniplex complex(GO:1990246)
1.7	58.8	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
1.7	3.4	GO:0031264	death-inducing signaling complex(GO:0031264)
1.7	36.6	GO:0030131	clathrin adaptor complex(GO:0030131)
1.7	15.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
1.7	6.6	GO:0043596	nuclear replication fork(GO:0043596)
1.6	11.5	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
1.6	24.7	GO:0042599	lamellar body(GO:0042599)
1.6	80.7	GO:0005811	lipid particle(GO:0005811)
1.6	8.2	GO:0005796	Golgi lumen(GO:0005796)
1.6	9.8	GO:0008385	IkappaB kinase complex(GO:0008385)
1.6	18.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
1.6	3.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
1.6	9.7	GO:0034464	BBSome(GO:0034464)
1.6	12.9	GO:0097539	ciliary transition fiber(GO:0097539)
1.6	3.2	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
1.6	4.8	GO:0030915	Smc5-Smc6 complex(GO:0030915)
1.6	4.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.6	12.6	GO:0032593	insulin-responsive compartment(GO:0032593)
1.6	1741.7	GO:0005654	nucleoplasm(GO:0005654)
1.6	6.3	GO:0000938	GARP complex(GO:0000938)
1.6	1.6	GO:1990423	RZZ complex(GO:1990423)
1.6	9.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
1.6	4.7	GO:0042612	MHC class I protein complex(GO:0042612)
1.6	7.8	GO:0005682	U5 snRNP(GO:0005682)
1.6	17.1	GO:0005916	fascia adherens(GO:0005916)
1.5	1.5	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.5	1.5	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.5	6.1	GO:0030312	external encapsulating structure(GO:0030312)
1.5	4.6	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.5	7.6	GO:0005657	replication fork(GO:0005657)
1.5	12.2	GO:0016600	flotillin complex(GO:0016600)
1.5	13.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.5	15.1	GO:0030126	COPI vesicle coat(GO:0030126)
1.5	10.5	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
1.5	25.6	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
1.5	4.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
1.5	3.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
1.5	8.9	GO:0044232	organelle membrane contact site(GO:0044232)
1.5	42.7	GO:0005801	cis-Golgi network(GO:0005801)
1.5	4.4	GO:0036157	outer dynein arm(GO:0036157)
1.5	49.5	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.4	5.8	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
1.4	5.7	GO:0005795	Golgi stack(GO:0005795)
1.4	9.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.4	5.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
1.4	2.8	GO:1990923	PET complex(GO:1990923)
1.4	2.8	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.4	2.8	GO:0097470	ribbon synapse(GO:0097470)
1.4	8.1	GO:0070820	tertiary granule(GO:0070820)
1.3	26.9	GO:0005776	autophagosome(GO:0005776)
1.3	9.3	GO:0033263	CORVET complex(GO:0033263)
1.3	9.3	GO:0000815	ESCRT III complex(GO:0000815)
1.3	4.0	GO:0044613	nuclear pore central transport channel(GO:0044613)
1.3	5.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.3	59.5	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
1.3	19.8	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
1.3	13.2	GO:0097440	apical dendrite(GO:0097440)
1.3	31.6	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
1.3	6.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
1.3	5.2	GO:0071010	prespliceosome(GO:0071010)
1.3	3.9	GO:0098536	deuterosome(GO:0098536)
1.3	3.9	GO:0097512	cardiac myofibril(GO:0097512)
1.3	35.9	GO:0005905	clathrin-coated pit(GO:0005905)
1.3	5.0	GO:0005869	dynactin complex(GO:0005869)
1.3	137.8	GO:0031965	nuclear membrane(GO:0031965)
1.2	27.5	GO:0035869	ciliary transition zone(GO:0035869)
1.2	3.7	GO:0042583	chromaffin granule(GO:0042583)
1.2	11.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.2	3.7	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.2	2.5	GO:0071437	invadopodium(GO:0071437)
1.2	2.4	GO:0045180	basal cortex(GO:0045180)
1.2	36.6	GO:0000502	proteasome complex(GO:0000502)
1.2	7.3	GO:0071986	Ragulator complex(GO:0071986)
1.2	43.4	GO:0030496	midbody(GO:0030496)
1.2	1.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
1.2	8.4	GO:0031512	motile primary cilium(GO:0031512)
1.2	19.1	GO:0005643	nuclear pore(GO:0005643)
1.2	75.2	GO:0005681	spliceosomal complex(GO:0005681)
1.2	5.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
1.2	11.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
1.2	3.6	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.2	3.5	GO:0000172	ribonuclease MRP complex(GO:0000172)
1.2	1.2	GO:0008091	spectrin(GO:0008091)
1.2	109.4	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.2	7.0	GO:0000801	central element(GO:0000801)
1.2	1.2	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
1.1	8.0	GO:0030008	TRAPP complex(GO:0030008)
1.1	4.6	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
1.1	3.4	GO:0044194	cytolytic granule(GO:0044194)
1.1	18.1	GO:0030992	intraciliary transport particle B(GO:0030992)
1.1	11.3	GO:0002102	podosome(GO:0002102)
1.1	4.5	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
1.1	72.1	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
1.1	4.5	GO:0030137	COPI-coated vesicle(GO:0030137)
1.1	22.3	GO:0005605	basal lamina(GO:0005605)
1.1	75.0	GO:0005759	mitochondrial matrix(GO:0005759)
1.1	1.1	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
1.1	6.5	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
1.1	7.6	GO:0097225	sperm midpiece(GO:0097225)
1.1	1.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.1	2.2	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.1	8.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.1	6.4	GO:0032009	early phagosome(GO:0032009)
1.1	140.0	GO:0005694	chromosome(GO:0005694)
1.0	13.6	GO:0002080	acrosomal membrane(GO:0002080)
1.0	5.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
1.0	63.9	GO:0019867	outer membrane(GO:0019867)
1.0	3.0	GO:0030430	host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
1.0	2.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0	3.0	GO:0097169	AIM2 inflammasome complex(GO:0097169)
1.0	3.0	GO:0045179	apical cortex(GO:0045179)
1.0	8.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.0	5.8	GO:0055029	DNA-directed RNA polymerase complex(GO:0000428) nuclear DNA-directed RNA polymerase complex(GO:0055029)
1.0	4.8	GO:0043020	NADPH oxidase complex(GO:0043020)
1.0	1.9	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
1.0	23.8	GO:0005844	polysome(GO:0005844)
1.0	196.0	GO:0005925	focal adhesion(GO:0005925)
0.9	46.4	GO:1990204	oxidoreductase complex(GO:1990204)
0.9	193.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.9	5.7	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.9	48.0	GO:0030139	endocytic vesicle(GO:0030139)
0.9	5.6	GO:0031430	M band(GO:0031430)
0.9	2.7	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.9	0.9	GO:0030990	intraciliary transport particle(GO:0030990)
0.9	11.8	GO:0014704	intercalated disc(GO:0014704)
0.9	15.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.9	0.9	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.9	1.8	GO:0072687	meiotic spindle(GO:0072687)
0.9	2.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.9	0.9	GO:0031501	mannosyltransferase complex(GO:0031501)
0.9	4.4	GO:0016272	prefoldin complex(GO:0016272)
0.9	8.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.9	248.8	GO:0005730	nucleolus(GO:0005730)
0.9	2.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.9	7.8	GO:0072546	ER membrane protein complex(GO:0072546)
0.9	3.5	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.9	15.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.9	558.2	GO:0005739	mitochondrion(GO:0005739)
0.8	0.8	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.8	2.5	GO:1990391	DNA repair complex(GO:1990391)
0.8	3.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.8	2.5	GO:0048179	activin receptor complex(GO:0048179)
0.8	3.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.8	1.6	GO:0070531	BRCA1-A complex(GO:0070531)
0.8	32.5	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.8	150.5	GO:0005815	microtubule organizing center(GO:0005815)
0.8	11.7	GO:0001772	immunological synapse(GO:0001772)
0.8	20.2	GO:0031985	Golgi cisterna(GO:0031985)
0.8	23.3	GO:0030863	cortical cytoskeleton(GO:0030863)
0.7	0.7	GO:0031902	late endosome membrane(GO:0031902)
0.7	111.2	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.7	38.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.7	18.9	GO:0055037	recycling endosome(GO:0055037)
0.7	5.7	GO:0042101	T cell receptor complex(GO:0042101)
0.7	1.4	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.7	3.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.7	426.3	GO:0005829	cytosol(GO:0005829)
0.7	29.8	GO:0005938	cell cortex(GO:0005938)
0.7	1.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.7	51.9	GO:0005874	microtubule(GO:0005874)
0.6	14.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.6	0.6	GO:0044316	cone cell pedicle(GO:0044316)
0.6	1.2	GO:0070695	FHF complex(GO:0070695)
0.6	1.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.6	1168.1	GO:0005634	nucleus(GO:0005634)
0.6	4.0	GO:0031672	A band(GO:0031672)
0.5	0.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.5	3.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5	1.0	GO:0044292	dendrite terminus(GO:0044292)
0.5	54.0	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.5	1.0	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5	0.5	GO:0005840	ribosome(GO:0005840)
0.5	0.9	GO:0071439	clathrin complex(GO:0071439)
0.5	2.7	GO:0008305	integrin complex(GO:0008305)
0.4	0.4	GO:0016528	sarcoplasm(GO:0016528)
0.4	0.4	GO:0097255	R2TP complex(GO:0097255)
0.4	0.8	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.4	8.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.4	1.9	GO:0016234	inclusion body(GO:0016234)
0.4	0.4	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.4	1.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.4	3.5	GO:0016328	lateral plasma membrane(GO:0016328)
0.3	0.7	GO:0005859	muscle myosin complex(GO:0005859)
0.3	2.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3	0.3	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.3	4.7	GO:0009925	basal plasma membrane(GO:0009925)
0.3	0.6	GO:0097546	ciliary base(GO:0097546)
0.3	1.8	GO:0032426	stereocilium tip(GO:0032426)
0.3	0.3	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.3	0.3	GO:0042581	specific granule(GO:0042581)
0.3	13.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.3	1.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3	0.8	GO:0043203	axon hillock(GO:0043203)
0.3	0.5	GO:0046691	intracellular canaliculus(GO:0046691)
0.3	1.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.2	0.4	GO:0001520	outer dense fiber(GO:0001520)
0.2	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	0.2	GO:1990716	axonemal central apparatus(GO:1990716)
0.2	0.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	0.7	GO:0030904	retromer complex(GO:0030904)
0.2	0.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	75.4	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	0.3	GO:0000922	spindle pole(GO:0000922)
0.2	2.3	GO:0016459	myosin complex(GO:0016459)
0.2	136.4	GO:0070062	extracellular exosome(GO:0070062)
0.1	0.9	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.1	0.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.1	GO:0045178	basal part of cell(GO:0045178)
0.1	0.1	GO:0030055	cell-substrate junction(GO:0030055)
0.1	0.1	GO:1990393	3M complex(GO:1990393)
0.1	0.1	GO:0019814	immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.1	6.7	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	2.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.1	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	4.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0060091	kinocilium(GO:0060091)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.5	10.5	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
9.5	38.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
8.8	26.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
8.8	70.1	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
8.6	25.7	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
8.5	34.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
8.5	33.9	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
8.2	32.8	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
8.2	8.2	GO:0042296	ISG15 transferase activity(GO:0042296)
7.9	23.8	GO:0017098	sulfonylurea receptor binding(GO:0017098)
7.8	23.5	GO:0050692	DBD domain binding(GO:0050692)
7.7	23.2	GO:1990188	euchromatin binding(GO:1990188)
7.5	52.6	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
7.4	22.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
7.3	14.6	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
7.1	21.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
6.9	27.6	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
6.6	19.9	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
6.6	19.9	GO:0031752	D5 dopamine receptor binding(GO:0031752)
6.2	24.9	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
6.2	24.6	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
6.1	18.4	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
6.1	36.7	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
6.1	18.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
6.0	17.9	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
5.9	17.8	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
5.9	17.6	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
5.8	109.9	GO:0031492	nucleosomal DNA binding(GO:0031492)
5.7	17.1	GO:0019961	interferon binding(GO:0019961)
5.7	17.1	GO:0050816	phosphothreonine binding(GO:0050816)
5.6	28.0	GO:1990239	steroid hormone binding(GO:1990239)
5.6	22.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
5.5	21.8	GO:0009374	biotin binding(GO:0009374)
5.4	32.7	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
5.4	16.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
5.2	15.5	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
5.0	15.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
5.0	25.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
5.0	15.0	GO:0070644	vitamin D response element binding(GO:0070644)
5.0	44.6	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
4.8	14.4	GO:0055100	adiponectin binding(GO:0055100)
4.8	14.4	GO:1990715	mRNA CDS binding(GO:1990715)
4.8	19.2	GO:0004046	aminoacylase activity(GO:0004046)
4.8	62.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
4.8	23.9	GO:0070061	fructose binding(GO:0070061)
4.8	43.0	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
4.8	19.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
4.7	19.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
4.7	14.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.7	14.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
4.7	18.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
4.6	13.9	GO:0004359	glutaminase activity(GO:0004359)
4.6	4.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
4.6	13.7	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
4.5	13.4	GO:0030350	iron-responsive element binding(GO:0030350)
4.4	8.8	GO:1990825	sequence-specific mRNA binding(GO:1990825)
4.4	21.9	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
4.4	52.4	GO:0017166	vinculin binding(GO:0017166)
4.4	17.4	GO:1990226	histone methyltransferase binding(GO:1990226)
4.3	26.0	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
4.3	25.8	GO:0008420	CTD phosphatase activity(GO:0008420)
4.3	29.8	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
4.3	21.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
4.3	12.8	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
4.2	126.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
4.2	16.8	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
4.2	24.9	GO:0034046	poly(G) binding(GO:0034046)
4.1	20.7	GO:0030274	LIM domain binding(GO:0030274)
4.1	16.5	GO:0035033	histone deacetylase regulator activity(GO:0035033)
4.0	4.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
4.0	8.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
4.0	95.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
4.0	15.8	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
4.0	15.8	GO:0070878	primary miRNA binding(GO:0070878)
3.9	51.2	GO:0008432	JUN kinase binding(GO:0008432)
3.9	7.7	GO:0050693	LBD domain binding(GO:0050693)
3.9	19.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
3.9	3.9	GO:0042809	vitamin D receptor binding(GO:0042809)
3.9	73.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
3.9	30.8	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
3.9	119.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
3.9	34.7	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
3.8	19.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
3.8	11.5	GO:0030519	snoRNP binding(GO:0030519)
3.8	23.0	GO:0045505	dynein intermediate chain binding(GO:0045505)
3.8	87.8	GO:0019206	nucleoside kinase activity(GO:0019206)
3.8	19.0	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
3.8	11.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
3.7	15.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
3.7	22.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
3.7	11.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
3.7	22.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
3.6	39.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
3.6	10.8	GO:0008142	oxysterol binding(GO:0008142)
3.6	92.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
3.6	14.3	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
3.6	7.1	GO:0019237	centromeric DNA binding(GO:0019237)
3.5	7.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
3.5	10.5	GO:0032142	single guanine insertion binding(GO:0032142)
3.5	7.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
3.5	31.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
3.4	17.1	GO:0070728	leucine binding(GO:0070728)
3.4	34.2	GO:0031996	thioesterase binding(GO:0031996)
3.4	13.4	GO:0070410	co-SMAD binding(GO:0070410)
3.3	10.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
3.3	36.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
3.3	6.6	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
3.3	43.0	GO:0046965	retinoid X receptor binding(GO:0046965)
3.3	36.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
3.3	23.1	GO:0035197	siRNA binding(GO:0035197)
3.3	9.9	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
3.3	16.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
3.3	13.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
3.3	3.3	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
3.3	9.8	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
3.3	19.6	GO:0001727	lipid kinase activity(GO:0001727)
3.3	3.3	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
3.3	9.8	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
3.2	29.2	GO:0019789	SUMO transferase activity(GO:0019789)
3.2	87.1	GO:0042162	telomeric DNA binding(GO:0042162)
3.2	35.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
3.2	9.5	GO:0004949	cannabinoid receptor activity(GO:0004949)
3.2	9.5	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
3.2	12.7	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
3.2	15.8	GO:0097322	7SK snRNA binding(GO:0097322)
3.1	15.7	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
3.1	15.7	GO:0004689	phosphorylase kinase activity(GO:0004689)
3.1	15.5	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
3.1	15.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
3.1	15.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.1	9.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
3.1	104.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
3.1	15.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
3.1	9.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.1	125.6	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
3.1	21.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
3.0	64.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
3.0	30.3	GO:0032452	histone demethylase activity(GO:0032452)
3.0	9.0	GO:0004064	arylesterase activity(GO:0004064)
3.0	35.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
3.0	5.9	GO:0035173	histone kinase activity(GO:0035173)
2.9	44.2	GO:0050681	androgen receptor binding(GO:0050681)
2.9	8.8	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.9	8.8	GO:0030619	U1 snRNA binding(GO:0030619)
2.9	8.7	GO:0050815	phosphoserine binding(GO:0050815)
2.9	26.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
2.9	14.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.9	5.8	GO:0030911	TPR domain binding(GO:0030911)
2.9	68.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
2.9	51.4	GO:0070491	repressing transcription factor binding(GO:0070491)
2.9	14.3	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.8	42.7	GO:0001221	transcription cofactor binding(GO:0001221)
2.8	42.6	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
2.8	11.3	GO:0004305	ethanolamine kinase activity(GO:0004305)
2.8	28.2	GO:0051010	microtubule plus-end binding(GO:0051010)
2.8	2.8	GO:0051434	BH3 domain binding(GO:0051434)
2.8	11.3	GO:0061665	SUMO ligase activity(GO:0061665)
2.8	8.4	GO:0016149	translation release factor activity, codon specific(GO:0016149)
2.8	8.4	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
2.8	11.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
2.8	8.3	GO:0036033	mediator complex binding(GO:0036033)
2.8	8.3	GO:0031014	troponin T binding(GO:0031014)
2.8	16.5	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
2.7	11.0	GO:0015232	heme transporter activity(GO:0015232)
2.7	8.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
2.7	21.9	GO:0035613	RNA stem-loop binding(GO:0035613)
2.7	5.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.7	10.9	GO:0000182	rDNA binding(GO:0000182)
2.7	5.4	GO:0005119	smoothened binding(GO:0005119)
2.7	10.8	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
2.7	2.7	GO:0051525	NFAT protein binding(GO:0051525)
2.7	8.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
2.7	26.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
2.7	48.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
2.6	5.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.6	13.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
2.6	28.7	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
2.6	33.9	GO:0046966	thyroid hormone receptor binding(GO:0046966)
2.6	5.2	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
2.6	2.6	GO:0003696	satellite DNA binding(GO:0003696)
2.6	7.8	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
2.6	15.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
2.6	10.3	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
2.6	18.0	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
2.6	5.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
2.6	12.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
2.5	5.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
2.5	48.3	GO:0003746	translation elongation factor activity(GO:0003746)
2.5	10.2	GO:0005534	galactose binding(GO:0005534)
2.5	15.2	GO:0008199	ferric iron binding(GO:0008199)
2.5	15.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
2.5	17.7	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
2.5	27.7	GO:0035497	cAMP response element binding(GO:0035497)
2.5	5.0	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.5	20.0	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
2.5	15.0	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
2.5	34.9	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
2.5	5.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
2.5	12.4	GO:0032184	SUMO polymer binding(GO:0032184)
2.5	4.9	GO:0061676	importin-alpha family protein binding(GO:0061676)
2.5	7.4	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
2.4	7.3	GO:0031686	A1 adenosine receptor binding(GO:0031686)
2.4	14.6	GO:0050897	cobalt ion binding(GO:0050897)
2.4	7.3	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
2.4	9.7	GO:0030984	kininogen binding(GO:0030984)
2.4	12.0	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
2.4	7.2	GO:0035174	histone serine kinase activity(GO:0035174) histone kinase activity (H3-S10 specific)(GO:0035175)
2.4	7.2	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
2.4	9.5	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
2.4	66.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
2.4	19.0	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
2.4	23.7	GO:0017154	semaphorin receptor activity(GO:0017154)
2.4	7.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
2.4	11.8	GO:0019960	C-X3-C chemokine binding(GO:0019960)
2.4	18.9	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.3	7.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
2.3	4.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
2.3	11.7	GO:0017040	ceramidase activity(GO:0017040)
2.3	4.7	GO:0051425	PTB domain binding(GO:0051425)
2.3	51.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
2.3	9.3	GO:0043559	insulin binding(GO:0043559)
2.3	32.4	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
2.3	6.9	GO:0000400	four-way junction DNA binding(GO:0000400)
2.3	11.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.3	11.4	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
2.3	6.8	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
2.3	2.3	GO:0035877	death effector domain binding(GO:0035877)
2.3	6.8	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
2.3	9.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.3	11.3	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
2.3	2.3	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
2.3	22.5	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
2.3	27.0	GO:0035326	enhancer binding(GO:0035326)
2.2	9.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.2	31.2	GO:0070717	poly-purine tract binding(GO:0070717)
2.2	15.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.2	33.3	GO:0043531	ADP binding(GO:0043531)
2.2	4.4	GO:0004104	cholinesterase activity(GO:0004104)
2.2	6.7	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
2.2	20.0	GO:0070568	guanylyltransferase activity(GO:0070568)
2.2	8.8	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
2.2	22.0	GO:0004407	histone deacetylase activity(GO:0004407)
2.2	6.6	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.2	13.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
2.2	17.4	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
2.2	4.3	GO:0034452	dynactin binding(GO:0034452)
2.2	6.5	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
2.2	19.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
2.2	8.7	GO:0045118	L-histidine transmembrane transporter activity(GO:0005290) azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
2.2	19.5	GO:0034576	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
2.1	6.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
2.1	23.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
2.1	6.4	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.1	38.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
2.1	32.1	GO:0017049	GTP-Rho binding(GO:0017049)
2.1	6.4	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
2.1	10.7	GO:0004301	epoxide hydrolase activity(GO:0004301)
2.1	4.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
2.1	12.7	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.1	21.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
2.1	4.2	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
2.1	12.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
2.1	14.8	GO:0004385	guanylate kinase activity(GO:0004385)
2.1	6.3	GO:0051380	beta-adrenergic receptor activity(GO:0004939) norepinephrine binding(GO:0051380)
2.1	6.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.1	16.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
2.1	6.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.1	6.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
2.1	27.0	GO:0001618	virus receptor activity(GO:0001618)
2.1	4.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
2.1	8.3	GO:0015057	thrombin receptor activity(GO:0015057)
2.1	6.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
2.1	4.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
2.1	6.2	GO:0005131	growth hormone receptor binding(GO:0005131)
2.1	6.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
2.1	10.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.1	32.9	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
2.0	8.2	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
2.0	66.8	GO:0035064	methylated histone binding(GO:0035064)
2.0	10.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
2.0	227.4	GO:0003714	transcription corepressor activity(GO:0003714)
2.0	4.0	GO:0001069	regulatory region RNA binding(GO:0001069)
2.0	2.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
2.0	13.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.0	77.0	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
2.0	7.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.0	17.7	GO:0001055	RNA polymerase II activity(GO:0001055)
2.0	2.0	GO:0070573	metallodipeptidase activity(GO:0070573)
2.0	82.1	GO:0016836	hydro-lyase activity(GO:0016836)
1.9	1.9	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.9	3.9	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.9	3.9	GO:0016803	hydrolase activity, acting on ether bonds(GO:0016801) ether hydrolase activity(GO:0016803)
1.9	25.3	GO:0001056	RNA polymerase III activity(GO:0001056)
1.9	7.8	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
1.9	21.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.9	7.7	GO:0002060	purine nucleobase binding(GO:0002060)
1.9	3.8	GO:0048185	activin binding(GO:0048185)
1.9	9.6	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.9	5.7	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
1.9	24.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
1.9	54.6	GO:0031593	polyubiquitin binding(GO:0031593)
1.9	5.6	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.9	7.5	GO:0032183	SUMO binding(GO:0032183)
1.9	3.7	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
1.9	14.9	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.9	37.2	GO:0008483	transaminase activity(GO:0008483)
1.9	3.7	GO:0031685	adenosine receptor binding(GO:0031685)
1.8	5.5	GO:0019002	GMP binding(GO:0019002)
1.8	7.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
1.8	7.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
1.8	11.1	GO:0050733	RS domain binding(GO:0050733)
1.8	12.9	GO:0016832	aldehyde-lyase activity(GO:0016832)
1.8	16.5	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
1.8	27.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
1.8	1.8	GO:0005049	nuclear export signal receptor activity(GO:0005049)
1.8	5.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
1.8	5.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.8	7.2	GO:0070513	death domain binding(GO:0070513)
1.8	25.3	GO:0001671	ATPase activator activity(GO:0001671)
1.8	1.8	GO:0004622	lysophospholipase activity(GO:0004622)
1.8	7.2	GO:0005047	signal recognition particle binding(GO:0005047)
1.8	10.8	GO:0031419	cobalamin binding(GO:0031419)
1.8	10.8	GO:0030983	mismatched DNA binding(GO:0030983)
1.8	12.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.8	3.6	GO:0043426	MRF binding(GO:0043426)
1.8	10.7	GO:0015288	porin activity(GO:0015288)
1.8	8.9	GO:0008430	selenium binding(GO:0008430)
1.8	5.3	GO:0031491	nucleosome binding(GO:0031491)
1.8	7.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
1.8	3.5	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
1.8	10.6	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
1.8	5.3	GO:0051734	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.8	7.1	GO:0042015	interleukin-20 binding(GO:0042015)
1.8	5.3	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.7	22.7	GO:0017091	AU-rich element binding(GO:0017091)
1.7	5.2	GO:1901612	cardiolipin binding(GO:1901612)
1.7	29.6	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
1.7	15.7	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.7	5.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
1.7	6.9	GO:0004594	pantothenate kinase activity(GO:0004594)
1.7	5.2	GO:0005128	erythropoietin receptor binding(GO:0005128)
1.7	5.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.7	3.4	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.7	3.4	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.7	22.2	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.7	285.8	GO:0043773	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
1.7	5.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
1.7	10.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.7	6.7	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.7	10.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.7	11.8	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
1.7	3.3	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
1.7	38.5	GO:0008536	Ran GTPase binding(GO:0008536)
1.7	6.7	GO:1990405	protein antigen binding(GO:1990405)
1.7	3.3	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
1.7	21.5	GO:0017025	TBP-class protein binding(GO:0017025)
1.7	5.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
1.7	3.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.7	34.7	GO:0070063	RNA polymerase binding(GO:0070063)
1.6	8.2	GO:0035473	lipase binding(GO:0035473)
1.6	8.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
1.6	19.5	GO:0003924	GTPase activity(GO:0003924)
1.6	22.6	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
1.6	8.1	GO:0008494	translation activator activity(GO:0008494)
1.6	3.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
1.6	95.0	GO:0031072	heat shock protein binding(GO:0031072)
1.6	86.9	GO:0017048	Rho GTPase binding(GO:0017048)
1.6	17.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
1.6	8.0	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.6	4.7	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.6	6.3	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
1.6	6.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
1.6	4.7	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.6	15.7	GO:0010181	FMN binding(GO:0010181)
1.6	20.4	GO:0008307	structural constituent of muscle(GO:0008307)
1.6	9.4	GO:0050321	tau-protein kinase activity(GO:0050321)
1.6	6.2	GO:0016778	diphosphotransferase activity(GO:0016778)
1.6	7.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.6	6.2	GO:0030515	snoRNA binding(GO:0030515)
1.6	15.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
1.5	3.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
1.5	12.4	GO:0005521	lamin binding(GO:0005521)
1.5	15.4	GO:0071889	14-3-3 protein binding(GO:0071889)
1.5	7.7	GO:0004668	protein-arginine deiminase activity(GO:0004668)
1.5	6.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.5	3.1	GO:0034618	arginine binding(GO:0034618)
1.5	35.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
1.5	4.6	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.5	10.7	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
1.5	3.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
1.5	4.5	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.5	18.0	GO:0045502	dynein binding(GO:0045502)
1.5	24.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.5	7.5	GO:0008097	5S rRNA binding(GO:0008097)
1.5	19.3	GO:0036002	pre-mRNA binding(GO:0036002)
1.5	5.9	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.5	30.9	GO:0003684	damaged DNA binding(GO:0003684)
1.5	1.5	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
1.5	55.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
1.5	10.2	GO:0070300	phosphatidic acid binding(GO:0070300)
1.5	68.5	GO:0003697	single-stranded DNA binding(GO:0003697)
1.5	4.4	GO:0031432	titin binding(GO:0031432)
1.5	14.6	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
1.5	21.8	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
1.4	8.7	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
1.4	4.3	GO:0016018	cyclosporin A binding(GO:0016018)
1.4	2.9	GO:0051959	dynein light intermediate chain binding(GO:0051959)
1.4	133.1	GO:0008276	protein methyltransferase activity(GO:0008276)
1.4	1.4	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.4	5.7	GO:0003688	DNA replication origin binding(GO:0003688)
1.4	1.4	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
1.4	2.9	GO:0070569	uridylyltransferase activity(GO:0070569)
1.4	19.9	GO:0051059	NF-kappaB binding(GO:0051059)
1.4	8.5	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.4	70.9	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
1.4	2.8	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.4	1.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
1.4	4.2	GO:0032794	GTPase activating protein binding(GO:0032794)
1.4	7.0	GO:0050700	CARD domain binding(GO:0050700)
1.4	46.1	GO:0005484	SNAP receptor activity(GO:0005484)
1.4	8.4	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
1.4	7.0	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
1.4	4.2	GO:1990460	leptin receptor binding(GO:1990460)
1.4	5.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
1.4	2.8	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
1.4	27.6	GO:0043130	ubiquitin binding(GO:0043130)
1.4	4.1	GO:0038100	nodal binding(GO:0038100)
1.4	8.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.4	128.0	GO:0017137	Rab GTPase binding(GO:0017137)
1.4	2.7	GO:0005113	patched binding(GO:0005113)
1.4	4.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.4	4.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.4	2.7	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
1.4	20.4	GO:0001047	core promoter binding(GO:0001047)
1.4	6.8	GO:0070064	proline-rich region binding(GO:0070064)
1.3	6.7	GO:0005536	glucose binding(GO:0005536)
1.3	58.8	GO:0003725	double-stranded RNA binding(GO:0003725)
1.3	6.6	GO:0004017	adenylate kinase activity(GO:0004017)
1.3	6.6	GO:0003993	acid phosphatase activity(GO:0003993)
1.3	31.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
1.3	1.3	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
1.3	5.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
1.3	5.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.3	11.8	GO:0034946	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
1.3	9.2	GO:0042043	neurexin family protein binding(GO:0042043)
1.3	16.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.3	2.6	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.3	3.9	GO:0071253	connexin binding(GO:0071253)
1.3	5.1	GO:0042609	CD4 receptor binding(GO:0042609)
1.3	7.7	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
1.3	3.8	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
1.3	7.7	GO:0043008	ATP-dependent protein binding(GO:0043008)
1.3	1.3	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
1.3	6.4	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.3	2.5	GO:1990446	snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
1.3	3.8	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.3	56.5	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
1.3	5.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
1.3	3.8	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
1.2	7.5	GO:0070891	lipoteichoic acid binding(GO:0070891)
1.2	3.7	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
1.2	9.9	GO:0051011	microtubule minus-end binding(GO:0051011)
1.2	3.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
1.2	14.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
1.2	9.9	GO:0004016	adenylate cyclase activity(GO:0004016)
1.2	4.9	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
1.2	52.9	GO:0019003	GDP binding(GO:0019003)
1.2	16.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
1.2	24.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.2	17.1	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.2	6.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
1.2	6.1	GO:0019238	GTP cyclohydrolase activity(GO:0003933) cyclohydrolase activity(GO:0019238)
1.2	21.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2	1.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
1.2	4.8	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.2	4.8	GO:0043522	leucine zipper domain binding(GO:0043522)
1.2	2.4	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
1.2	6.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
1.2	13.0	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
1.2	2.4	GO:0035671	enone reductase activity(GO:0035671)
1.2	3.5	GO:0000171	ribonuclease MRP activity(GO:0000171)
1.2	50.8	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
1.2	4.7	GO:0019808	polyamine binding(GO:0019808)
1.2	2.4	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
1.2	3.5	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
1.2	2.3	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
1.2	3.5	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.2	3.5	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1	1.1	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
1.1	1.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.1	2.3	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
1.1	3.4	GO:0070034	telomerase RNA binding(GO:0070034)
1.1	52.3	GO:0008565	protein transporter activity(GO:0008565)
1.1	6.8	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
1.1	26.0	GO:0042826	histone deacetylase binding(GO:0042826)
1.1	7.9	GO:0070567	cytidylyltransferase activity(GO:0070567)
1.1	2.2	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
1.1	16.8	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
1.1	22.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
1.1	27.9	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
1.1	14.5	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
1.1	14.5	GO:0043015	gamma-tubulin binding(GO:0043015)
1.1	8.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
1.1	1.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.1	6.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
1.1	2.2	GO:0019770	IgG receptor activity(GO:0019770)
1.1	16.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.1	5.5	GO:0070402	NADPH binding(GO:0070402)
1.1	19.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.1	772.1	GO:0044822	poly(A) RNA binding(GO:0044822)
1.1	7.6	GO:0030145	manganese ion binding(GO:0030145)
1.1	14.0	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
1.1	4.3	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.1	78.1	GO:0000287	magnesium ion binding(GO:0000287)
1.1	28.9	GO:0051087	chaperone binding(GO:0051087)
1.1	8.5	GO:0016866	intramolecular transferase activity(GO:0016866)
1.1	8.5	GO:0005123	death receptor binding(GO:0005123)
1.1	12.7	GO:0034792	sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
1.1	1.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.1	5.3	GO:0046624	sphingolipid transporter activity(GO:0046624)
1.1	7.4	GO:0008327	methyl-CpG binding(GO:0008327)
1.1	4.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.0	2.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
1.0	21.8	GO:0015301	anion:anion antiporter activity(GO:0015301)
1.0	1.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
1.0	1.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
1.0	6.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.0	3.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.0	12.2	GO:0008198	ferrous iron binding(GO:0008198)
1.0	122.7	GO:0003682	chromatin binding(GO:0003682)
1.0	2.0	GO:0031369	translation initiation factor binding(GO:0031369)
1.0	3.0	GO:0043014	alpha-tubulin binding(GO:0043014)
1.0	4.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
1.0	6.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
1.0	5.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
1.0	2.0	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
1.0	2.0	GO:0004075	biotin carboxylase activity(GO:0004075)
1.0	9.0	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.0	2.0	GO:0051185	coenzyme transporter activity(GO:0051185)
1.0	7.0	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.0	5.0	GO:0001054	RNA polymerase I activity(GO:0001054)
1.0	2.0	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.0	3.0	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
1.0	19.8	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.0	41.6	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
1.0	10.9	GO:0005372	water transmembrane transporter activity(GO:0005372)
1.0	6.9	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.0	2.9	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
1.0	6.8	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.0	8.8	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
1.0	2.9	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.0	2.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.0	3.9	GO:0043422	protein kinase B binding(GO:0043422)
1.0	3.9	GO:0070628	proteasome binding(GO:0070628)
1.0	2.9	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.0	88.5	GO:0003735	structural constituent of ribosome(GO:0003735)
1.0	1.9	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.9	6.6	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.9	10.4	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.9	1.9	GO:0031720	haptoglobin binding(GO:0031720)
0.9	6.6	GO:0034817	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.9	0.9	GO:0004771	sterol esterase activity(GO:0004771)
0.9	5.5	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.9	22.5	GO:0042393	histone binding(GO:0042393)
0.9	2.7	GO:0052813	phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.9	10.8	GO:0004521	endoribonuclease activity(GO:0004521)
0.9	0.9	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.9	0.9	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.9	4.5	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.9	9.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.9	6.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.9	5.4	GO:0004697	protein kinase C activity(GO:0004697)
0.9	4.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.9	2.7	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.9	4.4	GO:0034841	succinate-CoA ligase activity(GO:0004774) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.9	1.8	GO:0004126	cytidine deaminase activity(GO:0004126)
0.9	2.6	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.9	2.6	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.9	48.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.9	10.5	GO:0003712	transcription cofactor activity(GO:0003712)
0.9	2.6	GO:0032027	myosin light chain binding(GO:0032027)
0.9	51.7	GO:0003713	transcription coactivator activity(GO:0003713)
0.8	3.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.8	8.5	GO:0015245	fatty acid transporter activity(GO:0015245)
0.8	7.6	GO:0004568	chitinase activity(GO:0004568)
0.8	4.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.8	1.7	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.8	22.8	GO:0030674	protein binding, bridging(GO:0030674)
0.8	6.7	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.8	7.6	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.8	26.0	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.8	11.7	GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.8	2.5	GO:0051787	misfolded protein binding(GO:0051787)
0.8	1.7	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.8	11.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.8	1.7	GO:0042608	T cell receptor binding(GO:0042608)
0.8	3.3	GO:0043842	Kdo transferase activity(GO:0043842)
0.8	7.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.8	4.9	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.8	0.8	GO:0051920	peroxiredoxin activity(GO:0051920)
0.8	8.2	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.8	13.9	GO:0001848	complement binding(GO:0001848)
0.8	17.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.8	34.2	GO:0004175	endopeptidase activity(GO:0004175)
0.8	2.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.8	16.2	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.8	51.0	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.8	0.8	GO:0097617	annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.8	12.0	GO:0004177	aminopeptidase activity(GO:0004177)
0.8	17.6	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.8	11.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.8	0.8	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8	7.2	GO:0005523	tropomyosin binding(GO:0005523)
0.8	19.0	GO:0044823	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.8	3.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.8	14.7	GO:0016875	ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.8	8.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.8	5.4	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.8	4.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.8	3.8	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.7	68.2	GO:0008134	transcription factor binding(GO:0008134)
0.7	1.5	GO:2001070	starch binding(GO:2001070)
0.7	3.7	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7	20.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.7	0.7	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.7	1.5	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.7	4.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.7	3.7	GO:0030492	hemoglobin binding(GO:0030492)
0.7	3.6	GO:0070412	R-SMAD binding(GO:0070412)
0.7	90.9	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.7	9.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.7	5.7	GO:0019783	ubiquitin-like protein-specific protease activity(GO:0019783)
0.7	1.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.7	0.7	GO:0070698	type I activin receptor binding(GO:0070698)
0.7	3.5	GO:0031849	olfactory receptor binding(GO:0031849)
0.7	7.8	GO:0070566	adenylyltransferase activity(GO:0070566)
0.7	4.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.7	27.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.7	27.1	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.7	12.8	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.7	2.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.7	6.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7	3.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.7	10.7	GO:0005537	mannose binding(GO:0005537)
0.7	2.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.7	2.0	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.7	0.7	GO:0034061	DNA polymerase activity(GO:0034061)
0.7	2.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.7	3.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7	0.7	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.7	2.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.6	4.5	GO:0019966	interleukin-1 binding(GO:0019966)
0.6	5.7	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.6	0.6	GO:0030371	translation repressor activity(GO:0030371)
0.6	1.9	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.6	13.8	GO:0050699	WW domain binding(GO:0050699)
0.6	114.3	GO:0005525	GTP binding(GO:0005525)
0.6	3.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.6	1.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.6	3.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.6	1.8	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.6	2.4	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.6	1.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.6	10.8	GO:0016748	succinyltransferase activity(GO:0016748)
0.6	3.0	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.6	9.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.6	1.8	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.6	3.5	GO:0009055	electron carrier activity(GO:0009055)
0.6	3.4	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.6	1.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.6	1.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.6	0.6	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.6	1.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.6	0.6	GO:0019843	rRNA binding(GO:0019843)
0.6	2.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.5	12.6	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.5	9.9	GO:0030507	spectrin binding(GO:0030507)
0.5	1.6	GO:0019767	IgE receptor activity(GO:0019767)
0.5	11.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5	1.6	GO:0043515	kinetochore binding(GO:0043515)
0.5	22.1	GO:0005319	lipid transporter activity(GO:0005319)
0.5	2.7	GO:0002039	p53 binding(GO:0002039)
0.5	1.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5	403.8	GO:0003677	DNA binding(GO:0003677)
0.5	5.3	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5	1.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.5	16.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.5	2.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	1.6	GO:0070403	NAD+ binding(GO:0070403)
0.5	0.5	GO:0004096	catalase activity(GO:0004096)
0.5	2.0	GO:0016208	AMP binding(GO:0016208)
0.5	3.9	GO:0000049	tRNA binding(GO:0000049)
0.5	8.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.5	1.0	GO:0080014	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.5	1.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.5	1.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.5	3.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5	1.0	GO:0016854	racemase and epimerase activity(GO:0016854)
0.5	3.3	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.5	2.4	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.5	0.5	GO:0004518	nuclease activity(GO:0004518)
0.5	0.9	GO:0019213	deacetylase activity(GO:0019213)
0.5	0.9	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.5	2.3	GO:0050544	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.5	3.3	GO:0039706	co-receptor binding(GO:0039706)
0.5	1.4	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.5	0.5	GO:0051373	FATZ binding(GO:0051373)
0.5	1.8	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.4	1.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.4	3.1	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.4	2.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.4	3.1	GO:0019209	kinase activator activity(GO:0019209)
0.4	5.7	GO:0003785	actin monomer binding(GO:0003785)
0.4	42.4	GO:0003779	actin binding(GO:0003779)
0.4	2.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.4	2.2	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.4	1.8	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.4	1.7	GO:0050780	dopamine receptor binding(GO:0050780)
0.4	1.3	GO:0004645	phosphorylase activity(GO:0004645)
0.4	7.7	GO:0051117	ATPase binding(GO:0051117)
0.4	13.6	GO:0003676	nucleic acid binding(GO:0003676)
0.4	3.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.4	1.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.4	3.7	GO:0019239	deaminase activity(GO:0019239)
0.4	0.8	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4	0.4	GO:0031893	vasopressin receptor binding(GO:0031893)
0.4	1.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.4	0.8	GO:0003727	single-stranded RNA binding(GO:0003727)
0.4	0.8	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4	4.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.4	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.4	6.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.4	0.4	GO:0019957	C-C chemokine binding(GO:0019957)
0.4	7.9	GO:0005212	structural constituent of eye lens(GO:0005212)
0.4	0.8	GO:0005522	profilin binding(GO:0005522)
0.4	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	0.7	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.4	2.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4	1.4	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) glycine:sodium symporter activity(GO:0015375)
0.4	4.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.4	12.7	GO:0019887	protein kinase regulator activity(GO:0019887)
0.3	2.1	GO:0004540	ribonuclease activity(GO:0004540)
0.3	2.4	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.3	0.7	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	1.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3	1.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.3	3.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.3	3.9	GO:0016504	peptidase activator activity(GO:0016504)
0.3	13.7	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.3	1.3	GO:0008410	CoA-transferase activity(GO:0008410)
0.3	1.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	13.3	GO:0017124	SH3 domain binding(GO:0017124)
0.3	7.4	GO:0008168	methyltransferase activity(GO:0008168)
0.3	2.5	GO:0048038	quinone binding(GO:0048038)
0.3	0.9	GO:0044548	S100 protein binding(GO:0044548)
0.3	1.2	GO:0004966	galanin receptor activity(GO:0004966)
0.3	3.6	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.3	0.3	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.3	4.2	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.3	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.3	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.3	4.0	GO:0004519	endonuclease activity(GO:0004519)
0.3	11.6	GO:0003823	antigen binding(GO:0003823)
0.3	0.3	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.3	0.3	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3	1.4	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3	0.8	GO:0004946	bombesin receptor activity(GO:0004946)
0.3	25.2	GO:0003723	RNA binding(GO:0003723)
0.3	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.3	1.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.3	1.6	GO:0042288	MHC class I protein binding(GO:0042288)
0.3	0.3	GO:0004461	lactose synthase activity(GO:0004461)
0.3	10.2	GO:0019903	protein phosphatase binding(GO:0019903)
0.3	0.8	GO:0001595	angiotensin receptor activity(GO:0001595)
0.2	25.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	17.0	GO:0003774	motor activity(GO:0003774)
0.2	1.7	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2	0.7	GO:0019976	interleukin-2 binding(GO:0019976)
0.2	1.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.2	0.9	GO:0019865	immunoglobulin binding(GO:0019865)
0.2	0.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2	0.7	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.2	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2	36.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	0.2	GO:0038181	bile acid receptor activity(GO:0038181)
0.2	0.6	GO:0008147	structural constituent of bone(GO:0008147)
0.2	1.1	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.2	1.7	GO:0032451	demethylase activity(GO:0032451)
0.2	5.5	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.2	0.6	GO:0016015	morphogen activity(GO:0016015)
0.2	0.8	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.2	8.9	GO:0051015	actin filament binding(GO:0051015)
0.2	0.6	GO:0004967	glucagon receptor activity(GO:0004967)
0.2	0.7	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.2	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.2	2.8	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.2	0.2	GO:0031433	telethonin binding(GO:0031433)
0.2	0.8	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.2	18.2	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2	0.2	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.2	6.9	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
0.2	4.4	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2	0.2	GO:0001846	opsonin binding(GO:0001846)
0.2	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	3.0	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	0.5	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.1	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.1	0.1	GO:0019862	IgA binding(GO:0019862)
0.1	0.4	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	0.2	GO:1904680	oligopeptide transmembrane transporter activity(GO:0035673) peptide transmembrane transporter activity(GO:1904680)
0.1	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	29.5	GO:0008270	zinc ion binding(GO:0008270)
0.1	0.1	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.1	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.1	1.1	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.2	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1	0.1	GO:0016408	C-acyltransferase activity(GO:0016408)
0.1	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.3	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1	1.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	0.3	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	0.3	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.1	GO:0034212	peptide N-acetyltransferase activity(GO:0034212)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.3	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.1	1.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	2.7	GO:0005496	steroid binding(GO:0005496)
0.1	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.1	0.3	GO:0004556	alpha-amylase activity(GO:0004556)
0.1	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.0	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.0	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.0	0.1	GO:0019825	oxygen binding(GO:0019825)
0.0	0.5	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	1.1	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.0	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.0	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	1.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.3	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	0.3	GO:0005186	pheromone activity(GO:0005186)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	1.4	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0005550	pheromone binding(GO:0005550)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	97.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
5.1	71.6	PID IL5 PATHWAY	IL5-mediated signaling events
4.9	49.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
4.6	9.1	ST GAQ PATHWAY	G alpha q Pathway
4.5	113.3	PID IGF1 PATHWAY	IGF1 pathway
4.5	62.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
4.1	102.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
4.1	8.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
4.0	24.1	ST STAT3 PATHWAY	STAT3 Pathway
4.0	172.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
3.9	141.8	PID RHOA PATHWAY	RhoA signaling pathway
3.9	69.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
3.8	76.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
3.8	110.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.8	135.5	PID P53 REGULATION PATHWAY	p53 pathway
3.6	25.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
3.6	57.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
3.5	21.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
3.5	21.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
3.5	73.9	PID MYC PATHWAY	C-MYC pathway
3.4	24.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
3.4	50.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
3.3	143.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
3.2	22.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
3.2	13.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
3.2	35.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
3.2	34.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
3.1	34.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
3.1	71.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
3.1	24.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
3.0	12.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
3.0	161.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
3.0	57.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
3.0	137.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
2.8	31.2	PID IFNG PATHWAY	IFN-gamma pathway
2.7	8.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
2.7	48.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
2.7	88.7	PID MTOR 4PATHWAY	mTOR signaling pathway
2.6	41.8	PID TNF PATHWAY	TNF receptor signaling pathway
2.6	28.3	PID TRAIL PATHWAY	TRAIL signaling pathway
2.6	25.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
2.5	5.0	PID EPO PATHWAY	EPO signaling pathway
2.5	5.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
2.4	68.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
2.3	16.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
2.3	50.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
2.2	20.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
2.2	71.2	PID PLK1 PATHWAY	PLK1 signaling events
2.0	73.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
2.0	68.8	PID E2F PATHWAY	E2F transcription factor network
2.0	22.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
2.0	23.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
2.0	2.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
1.9	52.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.9	5.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
1.8	3.7	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.8	33.0	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.8	16.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
1.8	49.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.8	31.8	PID ARF6 PATHWAY	Arf6 signaling events
1.8	3.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
1.8	33.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
1.7	1.7	PID VEGFR1 PATHWAY	VEGFR1 specific signals
1.7	25.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
1.7	51.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
1.7	8.3	PID IL2 1PATHWAY	IL2-mediated signaling events
1.7	29.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
1.6	32.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.6	22.8	PID BARD1 PATHWAY	BARD1 signaling events
1.6	37.2	PID ILK PATHWAY	Integrin-linked kinase signaling
1.6	12.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.6	93.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
1.6	15.7	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
1.6	3.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
1.6	27.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
1.5	7.7	ST P38 MAPK PATHWAY	p38 MAPK Pathway
1.5	12.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
1.5	9.0	PID CD40 PATHWAY	CD40/CD40L signaling
1.5	1.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
1.4	31.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
1.4	25.3	PID LKB1 PATHWAY	LKB1 signaling events
1.4	18.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.3	4.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.3	9.4	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.3	13.2	PID IL1 PATHWAY	IL1-mediated signaling events
1.3	33.0	PID P73PATHWAY	p73 transcription factor network
1.3	11.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
1.3	32.7	PID RAC1 PATHWAY	RAC1 signaling pathway
1.3	9.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
1.3	14.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
1.3	11.5	PID INSULIN PATHWAY	Insulin Pathway
1.3	36.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
1.3	16.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
1.2	41.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
1.2	24.4	PID FANCONI PATHWAY	Fanconi anemia pathway
1.2	9.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.1	37.2	PID CMYB PATHWAY	C-MYB transcription factor network
1.1	10.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
1.1	5.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
1.1	5.4	PID ATR PATHWAY	ATR signaling pathway
1.1	15.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
1.1	11.7	SIG CHEMOTAXIS	Genes related to chemotaxis
1.1	4.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.0	7.3	PID ATM PATHWAY	ATM pathway
1.0	10.2	PID ARF 3PATHWAY	Arf1 pathway
1.0	19.3	PID AURORA B PATHWAY	Aurora B signaling
1.0	19.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.9	11.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.9	15.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.9	9.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.9	6.4	PID FOXO PATHWAY	FoxO family signaling
0.9	3.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.9	5.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.8	15.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.8	12.4	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.8	5.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.8	1.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.8	5.3	PID BCR 5PATHWAY	BCR signaling pathway
0.7	2.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.7	8.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.7	2.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.7	2.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	3.9	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.5	6.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.5	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5	11.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.5	2.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.4	6.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	9.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	2.9	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4	6.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.4	3.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.4	8.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.4	5.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.4	3.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	5.9	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.3	1.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.3	9.1	PID NOTCH PATHWAY	Notch signaling pathway
0.3	0.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.3	2.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	3.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.3	2.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	1.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	2.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.2	3.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	2.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.2	0.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	0.9	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.6	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.5	67.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
7.3	29.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
6.6	126.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
5.8	86.8	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
5.6	5.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
5.6	72.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
5.4	92.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
5.4	75.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
5.0	9.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
4.9	39.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
4.7	27.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
4.6	18.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
4.6	92.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
4.5	122.0	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
4.3	34.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
4.2	8.3	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
4.1	97.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
4.0	63.8	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
4.0	59.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
3.9	55.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
3.8	42.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
3.8	79.7	REACTOME G1 PHASE	Genes involved in G1 Phase
3.8	56.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
3.7	52.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
3.7	36.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
3.7	59.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
3.6	43.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
3.6	85.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
3.6	7.1	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
3.5	21.1	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
3.5	3.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
3.4	68.6	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
3.4	53.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
3.3	56.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
3.3	42.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
3.2	64.2	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
3.2	25.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
3.1	46.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
3.1	9.2	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
3.1	61.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
3.0	6.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
3.0	12.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
2.9	29.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
2.9	46.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
2.8	52.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
2.7	11.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
2.7	16.2	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
2.6	23.8	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
2.6	13.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
2.6	15.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.6	179.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
2.6	20.8	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
2.5	66.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
2.5	2.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
2.5	5.0	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
2.5	41.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
2.4	4.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
2.4	38.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
2.4	21.5	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
2.3	25.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
2.2	39.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
2.2	35.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
2.2	4.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
2.2	195.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
2.2	40.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
2.2	6.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
2.1	2.1	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
2.1	49.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
2.1	23.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.1	31.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.1	27.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
2.1	8.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
2.0	40.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
2.0	18.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
2.0	48.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
2.0	16.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
2.0	20.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
2.0	18.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.0	218.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
2.0	72.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
2.0	11.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
2.0	11.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
1.9	31.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
1.9	1.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
1.9	1.9	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
1.9	30.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
1.9	17.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
1.9	43.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
1.9	24.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.9	20.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
1.9	47.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
1.9	63.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
1.9	1.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.9	5.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.8	7.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.8	34.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.8	27.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.8	18.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
1.8	17.9	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
1.8	32.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
1.8	62.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
1.8	3.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
1.8	19.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
1.8	45.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.7	12.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.7	117.7	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.7	10.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.7	17.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
1.7	17.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.7	30.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.7	8.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
1.7	13.5	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
1.7	10.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.7	21.8	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
1.7	50.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
1.7	5.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
1.6	6.5	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
1.6	123.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
1.6	27.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
1.6	19.0	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
1.6	15.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
1.5	12.4	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
1.5	30.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.5	13.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.5	16.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.5	25.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
1.5	28.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.4	13.0	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
1.4	14.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.4	8.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.4	61.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.4	17.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
1.4	26.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
1.4	22.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.4	13.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.4	20.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
1.4	2.8	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
1.4	26.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
1.4	27.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.4	10.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
1.3	115.9	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.3	9.4	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
1.3	27.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
1.3	60.1	REACTOME TRANSLATION	Genes involved in Translation
1.3	10.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
1.3	16.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
1.3	19.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
1.3	2.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.3	7.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.2	1.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
1.2	16.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
1.2	4.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
1.2	6.0	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
1.2	2.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.2	12.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
1.2	14.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.2	1.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
1.1	19.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
1.1	33.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
1.1	13.7	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
1.1	6.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
1.1	8.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.1	34.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
1.1	39.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
1.1	8.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1	28.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.1	12.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1	12.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.0	7.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
1.0	5.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
1.0	10.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.0	10.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.0	10.0	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.0	14.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.9	20.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.9	18.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.9	5.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.9	11.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.9	39.4	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.9	7.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.9	25.7	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.9	18.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.9	7.0	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.9	5.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.9	2.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.8	31.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.8	15.5	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.8	12.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.8	3.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.8	3.2	REACTOME CELL CYCLE MITOTIC	Genes involved in Cell Cycle, Mitotic
0.8	1.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.8	30.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.8	3.9	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.7	5.9	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.7	47.5	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.7	29.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.7	40.6	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.7	17.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.7	0.7	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.7	2.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6	3.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.6	0.6	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.6	16.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.6	2.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.6	0.6	REACTOME METABOLISM OF RNA	Genes involved in Metabolism of RNA
0.6	2.9	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5	5.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	4.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.5	4.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.5	10.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.5	2.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.5	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	2.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.5	1.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.5	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	1.3	REACTOME TRANSCRIPTION	Genes involved in Transcription
0.4	12.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.4	0.8	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.4	2.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.4	2.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.4	2.8	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.3	0.7	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.3	1.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.3	0.9	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.3	3.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.3	2.0	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	4.7	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.3	1.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.3	4.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.2	5.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2	5.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	2.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	6.5	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.2	0.7	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.2	3.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	7.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	1.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	10.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.1	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.1	1.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.8	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.0	REACTOME DEFENSINS	Genes involved in Defensins

Results for Sp1

Z-value: 4.24

Motif logo

Transcription factors associated with Sp1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sp1 motif across conditions

Conditions sorted by the z-value of the Sp1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: