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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Spdef

Z-value: 1.07

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Transcription factors associated with Spdef

Gene Symbol	Gene ID	Gene Info
Spdef Ensembl NCBI MGI UniProt	ENSMUSG00000024215.7	SAM pointed domain containing ets transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_27712950_27713101	Spdef	4694	0.133214	0.41	2.2e-03	Click!
chr17_27719770_27719961	Spdef	1516	0.277248	0.36	7.3e-03	Click!
chr17_27716970_27717182	Spdef	643	0.595045	0.21	1.2e-01	Click!
chr17_27718373_27718524	Spdef	99	0.948050	0.10	4.8e-01	Click!

Activity of the Spdef motif across conditions

Conditions sorted by the z-value of the Spdef motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_66759799_66759950	2.45	Gm45911	predicted gene 45911	20206	0.19
chr11_72396620_72397004	2.14	Smtnl2	smoothelin-like 2	5929	0.13
chr8_88604116_88604818	1.88	Nkd1	naked cuticle 1	21662	0.15
chr9_31118626_31118863	1.85	St14	suppression of tumorigenicity 14 (colon carcinoma)	12983	0.15
chr6_127995929_127996080	1.75	Tspan9	tetraspanin 9	29187	0.14
chrX_13346707_13347908	1.70	Gm7129	predicted gene 7129	20288	0.14
chr11_94872744_94873468	1.70	A430060F13Rik	RIKEN cDNA A430060F13 gene	11347	0.12
chr10_76636101_76636288	1.68	Col6a2	collagen, type VI, alpha 2	12564	0.14
chr7_67031306_67031544	1.66	Adamts17	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17	16046	0.18
chr4_144404795_144404974	1.63	Pramef12os	PRAME family member 12, opposite strand	16	0.96
chr3_85202844_85202995	1.62	Gm38313	predicted gene, 38313	6472	0.27
chr7_27291768_27292241	1.62	Ltbp4	latent transforming growth factor beta binding protein 4	14966	0.09
chr5_150466046_150466511	1.61	Fry	FRY microtubule binding protein	5632	0.12
chr11_115843891_115844626	1.60	Llgl2	LLGL2 scribble cell polarity complex component	8994	0.1
chr17_83990134_83990296	1.59	8430430B14Rik	RIKEN cDNA 8430430B14 gene	8339	0.12
chr4_142221224_142221954	1.58	Kazn	kazrin, periplakin interacting protein	11383	0.22
chr11_97586031_97586182	1.58	Srcin1	SRC kinase signaling inhibitor 1	9920	0.12
chr6_21894482_21894640	1.54	Gm3289	predicted gene 3289	36383	0.14
chr11_98982435_98983067	1.48	Gjd3	gap junction protein, delta 3	265	0.84
chr11_46068856_46069025	1.45	Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	12882	0.13
chr6_72188837_72189690	1.44	Gm38832	predicted gene, 38832	26414	0.13
chr8_25108979_25109130	1.44	5830408C22Rik	RIKEN cDNA 5830408C22 gene	2056	0.22
chr15_101369582_101369733	1.41	Mir1941	microRNA 1941	305	0.59
chr3_122676170_122676500	1.41	Gm5981	predicted gene 5981	43064	0.1
chr14_72901649_72901800	1.38	Gm49295	predicted gene, 49295	435	0.86
chr15_79741326_79742933	1.37	Sun2	Sad1 and UNC84 domain containing 2	14	0.89
chr2_106822641_106822960	1.36	Gm22813	predicted gene, 22813	13464	0.23
chr4_150863884_150864035	1.36	Errfi1	ERBB receptor feedback inhibitor 1	8886	0.14
chr12_13845175_13845385	1.35	Gm49374	predicted gene, 49374	52943	0.11
chr14_22929660_22929842	1.35	Gm47601	predicted gene, 47601	1825	0.51
chr11_95077800_95077985	1.34	Itga3	integrin alpha 3	1091	0.4
chr8_106518885_106519036	1.34	Cdh3	cadherin 3	8069	0.17
chr17_25081196_25081377	1.34	Tmem204	transmembrane protein 204	96	0.94
chr14_25826323_25826518	1.33	Gm23701	predicted gene, 23701	1685	0.27
chr10_83648138_83649089	1.32	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	10	0.98
chr7_66790378_66790550	1.31	Cers3	ceramide synthase 3	26295	0.15
chr14_70191593_70192377	1.30	Sorbs3	sorbin and SH3 domain containing 3	12638	0.11
chr10_127062800_127064205	1.30	Cdk4	cyclin-dependent kinase 4	32	0.93
chr6_97882084_97882235	1.29	Gm15531	predicted gene 15531	8380	0.25
chr11_117098118_117098269	1.28	Gm11730	predicted gene 11730	1126	0.32
chr3_37876070_37876581	1.27	Gm20755	predicted gene, 20755	22488	0.14
chr13_6635743_6636106	1.26	Pfkp	phosphofructokinase, platelet	726	0.68
chr10_58341879_58342059	1.25	Gm23058	predicted gene, 23058	7635	0.18
chr5_103365190_103365721	1.25	5430427N15Rik	RIKEN cDNA 5430427N15 gene	8757	0.16
chr14_67955210_67955561	1.25	Dock5	dedicator of cytokinesis 5	21943	0.21
chr15_102393639_102394041	1.24	Sp1	trans-acting transcription factor 1	12303	0.09
chr10_75587812_75588191	1.24	Ggt5	gamma-glutamyltransferase 5	1339	0.25
chr5_122510586_122510930	1.22	Gm22965	predicted gene, 22965	3969	0.12
chr1_185587730_185587932	1.22	5033404E19Rik	RIKEN cDNA 5033404E19 gene	90443	0.07
chr2_174868662_174868813	1.22	Gm14616	predicted gene 14616	12448	0.17
chr4_137920578_137920751	1.22	Ece1	endothelin converting enzyme 1	6982	0.22
chr9_45504942_45505193	1.21	4833428L15Rik	RIKEN cDNA 4833428L15 gene	73337	0.07
chr10_31993382_31993579	1.21	Gm18189	predicted gene, 18189	19811	0.27
chr1_85093943_85094453	1.21	Gm10553	predicted gene 10553	5314	0.1
chr8_22744646_22744797	1.20	Plat	plasminogen activator, tissue	13006	0.15
chr15_99820038_99820222	1.19	Lima1	LIM domain and actin binding 1	13	0.93
chr5_136869816_136869999	1.19	Gm20485	predicted gene 20485	185	0.92
chr9_33858691_33858998	1.17	Gm47784	predicted gene, 47784	2359	0.32
chr17_70747742_70748497	1.17	5031415H12Rik	RIKEN cDNA 5031415H12 gene	7463	0.19
chr5_35943763_35943943	1.17	H2af-ps	H2A histone family, pseudogene	25956	0.19
chr7_96813584_96813778	1.16	Gm15416	predicted gene 15416	3804	0.17
chr16_25417962_25418220	1.16	Gm18896	predicted gene, 18896	25182	0.26
chr12_79928173_79928640	1.15	9430078K24Rik	RIKEN cDNA 9430078K24 gene	2912	0.27
chr7_99384032_99384637	1.15	Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	1564	0.33
chr11_4196645_4196957	1.14	Tbc1d10a	TBC1 domain family, member 10a	8622	0.1
chr9_102778125_102778630	1.14	Gm47416	predicted gene, 47416	6882	0.13
chr5_76079721_76079918	1.14	Gm6051	predicted gene 6051	19056	0.16
chr11_101885249_101885424	1.14	Gm11551	predicted gene 11551	901	0.48
chr7_71399222_71399577	1.13	Gm29328	predicted gene 29328	29066	0.17
chr16_17117479_17117630	1.13	2610318N02Rik	RIKEN cDNA 2610318N02 gene	222	0.82
chr7_118478749_118479078	1.13	Gm44652	predicted gene 44652	1582	0.33
chr15_27788001_27788934	1.13	Trio	triple functional domain (PTPRF interacting)	171	0.96
chr8_11277781_11277933	1.13	Col4a1	collagen, type IV, alpha 1	1799	0.32
chr8_108464219_108464370	1.13	Gm39244	predicted gene, 39244	72653	0.12
chr5_88426997_88427148	1.12	Gm7721	predicted gene 7721	741	0.58
chr8_91987831_91988212	1.12	Gm36670	predicted gene, 36670	3848	0.19
chr15_30383087_30383401	1.12	Gm49283	predicted gene, 49283	45600	0.17
chr10_86139467_86139618	1.12	Gm15990	predicted gene 15990	13715	0.17
chr9_56994536_56995264	1.12	Ptpn9	protein tyrosine phosphatase, non-receptor type 9	23	0.97
chr10_69652811_69653031	1.11	Ank3	ankyrin 3, epithelial	53375	0.16
chr5_15575271_15575990	1.11	Gm21083	predicted gene, 21083	1703	0.31
chr3_103647545_103647836	1.10	Atg4a-ps	autophagy related 4A, pseudogene	1622	0.29
chr15_99008836_99008987	1.10	Gm8973	predicted gene 8973	2854	0.13
chr10_41934443_41935500	1.10	Sesn1	sestrin 1	36598	0.15
chr4_103793953_103794326	1.10	Gm12719	predicted gene 12719	145402	0.04
chr17_30883683_30883834	1.10	Gm50242	predicted gene, 50242	3287	0.13
chr3_121713445_121713648	1.10	Gm43607	predicted gene 43607	1118	0.33
chr1_78353364_78353532	1.10	Gm28410	predicted gene 28410	13342	0.17
chr1_80218340_80218558	1.10	Fam124b	family with sequence similarity 124, member B	24	0.97
chr11_109180402_109180553	1.10	Gm11658	predicted gene 11658	20283	0.18
chr15_85669900_85671551	1.09	Lncppara	long noncoding RNA near Ppara	17109	0.13
chr16_87268014_87268522	1.09	N6amt1	N-6 adenine-specific DNA methyltransferase 1 (putative)	85917	0.08
chr11_80802849_80803185	1.08	Tmem98	transmembrane protein 98	7158	0.18
chr6_114818596_114818773	1.08	Gm44331	predicted gene, 44331	29294	0.14
chr8_13668439_13668623	1.08	Rasa3	RAS p21 protein activator 3	8920	0.18
chr7_99356524_99357152	1.08	Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	3599	0.18
chr11_75013005_75013592	1.08	Smg6	Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)	19445	0.11
chr5_100908593_100908744	1.07	Gm36793	predicted gene, 36793	5039	0.17
chr1_182519956_182520205	1.07	Capn2	calpain 2	2472	0.22
chr16_92845846_92846042	1.07	Gm49723	predicted gene, 49723	15933	0.22
chr11_97676145_97676296	1.07	Mllt6	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6	168	0.83
chr18_57744822_57744992	1.07	Gm19519	predicted gene, 19519	2658	0.32
chr10_76726106_76726272	1.06	Col6a1	collagen, type VI, alpha 1	21	0.97
chr7_101836268_101837136	1.06	Gm10602	predicted gene 10602	49	0.55
chr10_19494543_19494694	1.05	Gm33104	predicted gene, 33104	25	0.98
chr11_46212088_46212257	1.05	Fndc9	fibronectin type III domain containing 9	23359	0.11
chr6_120145527_120145724	1.05	Gm25327	predicted gene, 25327	1875	0.38
chr11_29839844_29840221	1.05	Gm12094	predicted gene 12094	343	0.85
chr7_65226424_65226575	1.04	1810049I09Rik	RIKEN cDNA 1810049I09 gene	13070	0.19
chr9_115356751_115357118	1.04	Mir467h	microRNA 467h	24885	0.11
chr16_38621153_38621308	1.04	Tmem39a	transmembrane protein 39a	33191	0.12
chr8_27059625_27060031	1.04	Plpbp	pyridoxal phosphate binding protein	9054	0.1
chr16_21402126_21402344	1.04	Vps8	VPS8 CORVET complex subunit	20883	0.21
chr11_94565288_94565483	1.04	Chad	chondroadherin	338	0.77
chr12_80243512_80243663	1.04	Actn1	actinin, alpha 1	15197	0.14
chr18_34380015_34380186	1.04	Reep5	receptor accessory protein 5	6030	0.18
chr17_66564336_66564602	1.04	Themis3	thymocyte selection associated family member 3	30152	0.13
chr1_133471115_133471288	1.04	Sox13	SRY (sex determining region Y)-box 13	46824	0.12
chr14_46885106_46885668	1.03	2810457G06Rik	RIKEN cDNA 2810457G06 gene	323	0.74
chr16_14936552_14936972	1.03	Efcab1	EF-hand calcium binding domain 1	30097	0.18
chr4_120199286_120199480	1.03	Edn2	endothelin 2	38177	0.17
chr11_62761232_62761388	1.03	Zfp286os	zinc finger protein 286, opposite strand	74	0.9
chr12_73617716_73617931	1.03	Prkch	protein kinase C, eta	31098	0.17
chr1_85587003_85587479	1.03	Sp110	Sp110 nuclear body protein	1950	0.18
chr1_64809148_64809517	1.03	Plekhm3	pleckstrin homology domain containing, family M, member 3	27432	0.16
chr14_76582580_76582731	1.03	Serp2	stress-associated endoplasmic reticulum protein family member 2	25766	0.17
chr7_113241928_113242079	1.03	Arntl	aryl hydrocarbon receptor nuclear translocator-like	2249	0.33
chr14_65943340_65943548	1.02	Scara3	scavenger receptor class A, member 3	10491	0.16
chr5_122319933_122320155	1.02	Gm15842	predicted gene 15842	17622	0.09
chr2_139322550_139322711	1.02	Gm14071	predicted gene 14071	61710	0.15
chr11_88556113_88556320	1.02	Msi2	musashi RNA-binding protein 2	33931	0.19
chr1_172431988_172432180	1.02	Gm7804	predicted gene 7804	26485	0.1
chr8_104623879_104624158	1.02	Cdh16	cadherin 16	69	0.94
chr17_12724917_12725682	1.01	Airn	antisense Igf2r RNA	16012	0.13
chr7_55877895_55878059	1.01	Cyfip1	cytoplasmic FMR1 interacting protein 1	6118	0.16
chr17_71698269_71698678	1.01	Togaram2	TOG array regulator of axonemal microtubules 2	11772	0.12
chr6_86775025_86775336	1.01	Anxa4	annexin A4	9270	0.14
chr10_82971574_82971860	1.01	Chst11	carbohydrate sulfotransferase 11	13781	0.16
chr3_3526060_3526383	1.01	Hnf4g	hepatocyte nuclear factor 4, gamma	18191	0.19
chr5_72382164_72382315	1.01	Corin	corin, serine peptidase	1951	0.29
chr18_38844439_38844590	1.01	Fgf1	fibroblast growth factor 1	14234	0.2
chr1_125013472_125013798	1.01	Dpp10	dipeptidylpeptidase 10	167596	0.04
chr10_64641714_64641867	1.01	Gm23854	predicted gene, 23854	337046	0.01
chr8_103808304_103808473	1.00	4933400L20Rik	RIKEN cDNA 4933400L20 gene	204589	0.02
chr8_65175201_65175352	1.00	Gm45249	predicted gene 45249	8968	0.16
chr17_28272946_28273120	1.00	Ppard	peroxisome proliferator activator receptor delta	914	0.44
chr14_105979516_105979713	1.00	Spry2	sprouty RTK signaling antagonist 2	82795	0.08
chr4_132365771_132365937	0.99	Phactr4	phosphatase and actin regulator 4	4677	0.08
chr4_154333391_154333568	0.99	Prdm16	PR domain containing 16	1373	0.37
chr1_179667564_179668717	0.99	Sccpdh	saccharopine dehydrogenase (putative)	70	0.98
chr11_76130922_76131073	0.99	Vps53	VPS53 GARP complex subunit	7751	0.17
chr12_100998055_100998407	0.99	Gm36756	predicted gene, 36756	5259	0.14
chr8_121301989_121302140	0.98	Gm26815	predicted gene, 26815	54772	0.12
chr11_101246694_101246858	0.98	Ramp2	receptor (calcitonin) activity modifying protein 2	157	0.87
chr10_80282884_80283245	0.98	Gm15122	predicted gene 15122	58	0.66
chr2_159356589_159356740	0.98	Gm14219	predicted gene 14219	99793	0.08
chr16_31460264_31460464	0.97	Bdh1	3-hydroxybutyrate dehydrogenase, type 1	2248	0.22
chr19_56631716_56631870	0.97	Gm32441	predicted gene, 32441	32818	0.14
chr2_46065466_46065617	0.97	Gm23072	predicted gene, 23072	240795	0.02
chr19_53087327_53087803	0.97	1700054A03Rik	RIKEN cDNA 1700054A03 gene	6788	0.17
chr7_18858684_18858835	0.97	Pglyrp1	peptidoglycan recognition protein 1	12572	0.09
chr16_57393177_57393620	0.97	Filip1l	filamin A interacting protein 1-like	40121	0.14
chr1_90927447_90927603	0.96	Mlph	melanophilin	154	0.95
chr14_25186025_25186330	0.96	4930572O13Rik	RIKEN cDNA 4930572O13 gene	42936	0.14
chr13_41643710_41644066	0.96	Gm5082	predicted gene 5082	5555	0.21
chr11_62251114_62251334	0.96	Adora2b	adenosine A2b receptor	2240	0.25
chr9_72653649_72653836	0.96	Nedd4	neural precursor cell expressed, developmentally down-regulated 4	8604	0.1
chr8_126634786_126634974	0.96	Irf2bp2	interferon regulatory factor 2 binding protein 2	40894	0.17
chr12_25534023_25534374	0.95	Gm36723	predicted gene, 36723	139443	0.05
chr14_71010686_71010837	0.95	Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	68875	0.11
chr15_63193961_63194112	0.95	Gm49013	predicted gene, 49013	47803	0.14
chr6_82721442_82721593	0.95	Hk2	hexokinase 2	4792	0.17
chr6_92034800_92034951	0.94	4930466I24Rik	RIKEN cDNA 4930466I24 gene	18758	0.14
chr7_98469184_98469371	0.94	Gucy2d	guanylate cyclase 2d	1583	0.25
chr7_116882332_116882634	0.94	Gm4366	predicted gene 4366	56632	0.13
chr8_66761088_66761239	0.94	Gm45911	predicted gene 45911	18917	0.19
chr10_39613115_39613645	0.94	Gm16364	predicted gene 16364	287	0.63
chr2_173558872_173559023	0.94	Ankrd60	ankyrin repeat domain 60	19251	0.17
chr17_13547995_13548243	0.93	Gm26375	predicted gene, 26375	13950	0.13
chr8_57398171_57398322	0.93	Gm34099	predicted gene, 34099	4858	0.18
chr10_81383963_81384933	0.93	Dohh	deoxyhypusine hydroxylase/monooxygenase	11	0.48
chr9_43253272_43253649	0.93	D630033O11Rik	RIKEN cDNA D630033O11 gene	6420	0.17
chr2_31991062_31991213	0.93	Nup214	nucleoporin 214	3684	0.13
chr1_85281731_85282030	0.92	Gm16026	predicted pseudogene 16026	6773	0.13
chr9_56868674_56868825	0.92	Cspg4	chondroitin sulfate proteoglycan 4	3716	0.15
chr8_106308415_106308839	0.92	Gm10629	predicted gene 10629	25320	0.14
chr1_13770999_13771390	0.92	Gm26273	predicted gene, 26273	3270	0.26
chr17_31456805_31457104	0.92	Pde9a	phosphodiesterase 9A	3622	0.13
chr9_107981626_107982218	0.91	Uba7	ubiquitin-like modifier activating enzyme 7	1032	0.19
chr14_7954033_7954557	0.91	Gm45521	predicted gene 45521	2993	0.24
chr13_64417088_64417239	0.91	Cdk20	cyclin-dependent kinase 20	15151	0.1
chr1_85614060_85614490	0.91	Gm10552	predicted gene 10552	2379	0.15
chr13_68778081_68778232	0.91	Gm26929	predicted gene, 26929	31924	0.2
chr13_104989113_104989279	0.91	Rgs7bp	regulator of G-protein signalling 7 binding protein	65734	0.11
chr16_35256154_35256357	0.91	Adcy5	adenylate cyclase 5	14407	0.16
chr8_65129513_65129677	0.91	Smim31	small integral membrane protein 31	32	0.96
chr15_34412153_34412544	0.91	Gm24523	predicted gene, 24523	28574	0.1
chr15_54534137_54534505	0.91	Mal2	mal, T cell differentiation protein 2	36871	0.16
chr16_17809524_17810128	0.91	Scarf2	scavenger receptor class F, member 2	5017	0.1
chr4_98758120_98758271	0.91	Gm17376	predicted gene, 17376	12460	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4	1.2	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.4	1.2	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.3	1.8	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.3	0.9	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.3	1.2	GO:0010288	response to lead ion(GO:0010288)
0.3	0.9	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.2	0.7	GO:0072144	glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.2	0.7	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2	1.5	GO:0005513	detection of calcium ion(GO:0005513)
0.2	0.6	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	1.0	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.2	1.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	0.8	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2	0.6	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.2	0.6	GO:0046103	inosine biosynthetic process(GO:0046103)
0.2	0.6	GO:0061356	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.2	0.6	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2	0.2	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.2	0.9	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.2	0.5	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.2	0.5	GO:0046864	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.2	0.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.2	0.5	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2	0.7	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.2	1.5	GO:0016264	gap junction assembly(GO:0016264)
0.2	0.5	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.2	0.9	GO:0050748	negative regulation of lipoprotein metabolic process(GO:0050748)
0.1	0.4	GO:0060931	sinoatrial node cell development(GO:0060931)
0.1	0.4	GO:0060137	maternal process involved in parturition(GO:0060137)
0.1	0.9	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1	0.4	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1	1.0	GO:0070831	basement membrane assembly(GO:0070831)
0.1	0.6	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1	0.4	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.7	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.1	0.5	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1	1.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.7	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	0.6	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.8	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	0.3	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.1	0.4	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.4	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.4	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.4	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.1	0.2	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.1	0.6	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	1.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.1	0.4	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.1	0.6	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1	0.6	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.1	0.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.3	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.2	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.9	GO:0060346	bone trabecula formation(GO:0060346)
0.1	0.6	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.3	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.1	0.7	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.3	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.5	GO:0006547	histidine metabolic process(GO:0006547) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1	0.3	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	2.5	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.4	GO:0014029	neural crest formation(GO:0014029)
0.1	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
0.1	0.3	GO:0051794	regulation of catagen(GO:0051794)
0.1	0.5	GO:0042045	epithelial fluid transport(GO:0042045)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.1	0.2	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.3	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.3	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
0.1	0.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.2	GO:0048143	astrocyte activation(GO:0048143)
0.1	0.7	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.1	0.3	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.4	GO:0030035	microspike assembly(GO:0030035)
0.1	0.5	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.5	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	1.7	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.4	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1	0.1	GO:1901203	positive regulation of extracellular matrix assembly(GO:1901203)
0.1	0.3	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.1	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.1	0.2	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1	0.3	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.1	0.9	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.2	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.1	GO:0035793	cell migration involved in kidney development(GO:0035787) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1	0.2	GO:0035973	aggrephagy(GO:0035973)
0.1	0.2	GO:1903011	negative regulation of bone development(GO:1903011)
0.1	0.3	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.3	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.1	0.2	GO:0023021	termination of signal transduction(GO:0023021)
0.1	0.1	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1	0.2	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.1	0.2	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	0.3	GO:0051031	tRNA transport(GO:0051031)
0.1	1.4	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.5	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.6	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.1	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.1	GO:0032512	regulation of protein phosphatase type 2B activity(GO:0032512)
0.1	0.4	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.1	0.2	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.1	0.2	GO:0070836	caveola assembly(GO:0070836)
0.1	0.4	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.2	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	0.2	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1	0.1	GO:0002086	diaphragm contraction(GO:0002086)
0.1	0.3	GO:0060068	vagina development(GO:0060068)
0.1	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.7	GO:0010819	regulation of T cell chemotaxis(GO:0010819)
0.1	0.4	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.2	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1	0.3	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.2	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.1	0.1	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1	0.9	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.2	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1	0.1	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1	0.3	GO:0043307	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.1	0.2	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	1.3	GO:0030318	melanocyte differentiation(GO:0030318)
0.1	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.1	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.1	0.2	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1	0.3	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.3	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.1	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.1	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.1	0.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.1	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.1	0.1	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.1	0.4	GO:1990000	amyloid fibril formation(GO:1990000)
0.1	0.1	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	0.1	GO:0032439	endosome localization(GO:0032439)
0.1	0.8	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1	0.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.1	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.7	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	0.7	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.4	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1	0.2	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.1	0.3	GO:0030222	eosinophil differentiation(GO:0030222)
0.1	0.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.1	0.2	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.1	0.4	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.3	GO:0032196	transposition(GO:0032196)
0.1	0.1	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.4	GO:0035810	positive regulation of urine volume(GO:0035810)
0.1	0.2	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.1	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.4	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	0.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.1	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.1	0.2	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.1	0.2	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1	0.2	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.4	GO:0030432	peristalsis(GO:0030432)
0.1	0.3	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	0.1	GO:2000562	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1	0.5	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.2	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.1	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.3	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.6	GO:0033622	integrin activation(GO:0033622)
0.1	0.3	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.1	0.2	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.3	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.1	0.2	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.1	1.5	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.1	0.3	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.1	0.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.6	GO:0060065	uterus development(GO:0060065)
0.1	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.1	0.3	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.1	0.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.2	GO:0061042	vascular wound healing(GO:0061042)
0.1	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.4	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.1	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.3	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1	0.6	GO:0051601	exocyst localization(GO:0051601)
0.1	0.2	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.1	0.1	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.1	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1	0.2	GO:0008355	olfactory learning(GO:0008355)
0.1	0.2	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.0	GO:0021824	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0	0.0	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.0	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.7	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.3	GO:0034350	regulation of glial cell apoptotic process(GO:0034350)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.5	GO:0002467	germinal center formation(GO:0002467)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.4	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.2	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.2	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	4.6	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.8	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.7	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.1	GO:0032348	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of cortisol biosynthetic process(GO:2000064) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.3	GO:0060347	heart trabecula formation(GO:0060347)
0.0	0.0	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.4	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.4	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.8	GO:0033198	response to ATP(GO:0033198)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.1	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.2	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.0	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
0.0	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.4	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0097484	dendrite extension(GO:0097484)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.4	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.3	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.6	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.3	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0	0.2	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.1	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	0.9	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.7	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0048793	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) pronephros development(GO:0048793)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.3	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.3	GO:0003338	metanephros morphogenesis(GO:0003338)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0	0.1	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.1	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.0	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.0	0.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.4	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0006522	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
0.0	0.2	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.0	GO:0061642	chemoattraction of axon(GO:0061642)
0.0	0.1	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0071839	apoptotic process in bone marrow(GO:0071839)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:0001768	establishment of lymphocyte polarity(GO:0001767) establishment of T cell polarity(GO:0001768)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.4	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0032060	bleb assembly(GO:0032060)
0.0	0.5	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.0	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.4	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.1	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.4	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.0	0.0	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.9	GO:0007044	cell-substrate junction assembly(GO:0007044)
0.0	0.0	GO:0035733	hepatic stellate cell activation(GO:0035733)
0.0	0.1	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.4	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.1	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.0	0.1	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0033278	cell proliferation in midbrain(GO:0033278)
0.0	0.1	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.1	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.0	1.0	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.1	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.0	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.4	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
0.0	0.1	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.2	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.2	GO:0043206	extracellular fibril organization(GO:0043206)
0.0	0.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.1	GO:1904181	positive regulation of membrane depolarization(GO:1904181)
0.0	0.4	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.5	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.4	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.0	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534)
0.0	0.4	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.0	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.1	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.0	GO:0035740	CD8-positive, alpha-beta T cell proliferation(GO:0035740)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.0	GO:0071335	hair follicle cell proliferation(GO:0071335)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.2	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.0	0.3	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.1	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0	0.0	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.2	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0	0.1	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.3	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
0.0	0.2	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.3	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.2	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.1	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0061339	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:1901563	cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.0	0.0	GO:0003383	apical constriction(GO:0003383)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.6	GO:0042596	fear response(GO:0042596)
0.0	0.0	GO:0014827	intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.1	GO:0072366	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0060600	dichotomous subdivision of an epithelial terminal unit(GO:0060600)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.0	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.1	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.0	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.0	GO:0033058	directional locomotion(GO:0033058)
0.0	0.0	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.0	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.1	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0	0.0	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0070293	renal absorption(GO:0070293)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.0	GO:0060534	trachea cartilage development(GO:0060534)
0.0	0.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.2	GO:0097186	amelogenesis(GO:0097186)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.0	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.0	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.2	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.0	0.1	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.3	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.0	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.0	0.0	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.0	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.0	GO:0001927	exocyst assembly(GO:0001927)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.1	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.5	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.0	GO:0072240	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.1	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.0	0.1	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.0	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.0	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:0060043	regulation of cardiac muscle cell proliferation(GO:0060043)
0.0	0.0	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.2	GO:0019377	glycolipid catabolic process(GO:0019377)
0.0	0.0	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.0	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0	0.2	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.1	GO:0001780	neutrophil homeostasis(GO:0001780)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.0	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.0	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0	0.1	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.0	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.0	0.1	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.0	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.2	GO:0098586	cellular response to virus(GO:0098586)
0.0	0.1	GO:0034650	cortisol metabolic process(GO:0034650)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.1	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.2	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.2	GO:0015893	drug transport(GO:0015893)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.0	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0034165	regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0030501	positive regulation of bone mineralization(GO:0030501)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.0	0.1	GO:2000194	regulation of female gonad development(GO:2000194)
0.0	0.0	GO:0015791	polyol transport(GO:0015791)
0.0	0.2	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.2	GO:0071474	cellular hyperosmotic response(GO:0071474)
0.0	0.0	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.0	0.0	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.0	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0	0.0	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.0	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.0	GO:0034349	glial cell apoptotic process(GO:0034349)
0.0	0.2	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.0	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0	0.0	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.0	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.1	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.2	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.0	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.0	GO:0014857	regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0	0.0	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.0	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.3	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.0	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.0	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0	0.2	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.0	GO:0008078	mesodermal cell migration(GO:0008078)
0.0	0.0	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.0	GO:0006113	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.0	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	1.0	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2	1.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.5	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.5	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.4	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	0.8	GO:0005861	troponin complex(GO:0005861)
0.1	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.5	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.8	GO:0045179	apical cortex(GO:0045179)
0.1	0.5	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0097443	sorting endosome(GO:0097443)
0.1	0.3	GO:0032127	dense core granule membrane(GO:0032127)
0.1	1.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	0.4	GO:0071953	elastic fiber(GO:0071953)
0.1	0.2	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.3	GO:0043293	apoptosome(GO:0043293)
0.1	0.7	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.4	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.7	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.9	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	1.5	GO:0005922	connexon complex(GO:0005922)
0.1	4.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.3	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.3	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	1.0	GO:0000145	exocyst(GO:0000145)
0.1	0.6	GO:0001527	microfibril(GO:0001527)
0.1	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.5	GO:0036128	CatSper complex(GO:0036128)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.6	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	0.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.8	GO:0043196	varicosity(GO:0043196)
0.1	0.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	1.0	GO:0001673	male germ cell nucleus(GO:0001673)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.1	0.7	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	1.9	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.1	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.6	GO:0097225	sperm midpiece(GO:0097225)
0.0	1.1	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.6	GO:0031430	M band(GO:0031430)
0.0	0.5	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.0	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.4	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.3	GO:0032433	filopodium tip(GO:0032433)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.0	GO:1990696	USH2 complex(GO:1990696)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.4	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	1.9	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	1.1	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.7	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	4.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0005921	gap junction(GO:0005921)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.1	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	1.1	GO:0031526	brush border membrane(GO:0031526)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.6	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.0	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.0	0.0	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.0	GO:0044393	microspike(GO:0044393)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	1.0	GO:0043204	perikaryon(GO:0043204)
0.0	0.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.0	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	1.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.3	1.1	GO:0042731	PH domain binding(GO:0042731)
0.3	0.8	GO:0051373	FATZ binding(GO:0051373)
0.2	0.7	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	0.7	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2	0.6	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.2	0.8	GO:0002046	opsin binding(GO:0002046)
0.2	2.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.0	GO:0030274	LIM domain binding(GO:0030274)
0.2	0.6	GO:0019770	IgG receptor activity(GO:0019770)
0.2	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	2.0	GO:0044548	S100 protein binding(GO:0044548)
0.2	0.8	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2	0.5	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	0.8	GO:0004111	creatine kinase activity(GO:0004111)
0.2	0.8	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	0.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	0.5	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2	0.5	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.4	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.5	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1	0.5	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.1	0.9	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	1.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.6	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.5	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	0.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.4	GO:0030172	troponin C binding(GO:0030172)
0.1	0.6	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.3	GO:0035514	DNA demethylase activity(GO:0035514)
0.1	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	1.2	GO:0017166	vinculin binding(GO:0017166)
0.1	0.5	GO:0034580	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.1	0.5	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	1.5	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.7	GO:0034802	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.3	GO:0004802	transketolase activity(GO:0004802)
0.1	0.4	GO:0051434	BH3 domain binding(GO:0051434)
0.1	0.7	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1	1.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	1.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.4	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.3	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	1.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.5	GO:0033265	choline binding(GO:0033265)
0.1	0.4	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.6	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.1	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.1	0.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.8	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.1	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.1	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	3.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	1.2	GO:0030552	cAMP binding(GO:0030552)
0.1	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.2	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.8	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.4	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.2	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.3	GO:0034711	inhibin binding(GO:0034711)
0.1	0.3	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.1	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.2	GO:0045503	dynein light chain binding(GO:0045503)
0.0	1.3	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.3	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.6	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.9	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.6	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.7	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	1.3	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.3	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.3	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	1.2	GO:0043738	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0	0.3	GO:0018856	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.4	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.4	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.3	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.5	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	1.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0	0.4	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.8	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	1.8	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0	0.1	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.7	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.0	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.6	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.5	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.5	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.8	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.6	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.4	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	1.4	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	1.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.0	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0	0.0	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.6	GO:0018715	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0	0.0	GO:0071814	lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	1.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.5	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.7	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.0	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.0	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.3	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.0	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:0004096	catalase activity(GO:0004096)
0.0	0.0	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0001962	alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0008759	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.0	GO:0043829	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0	0.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.0	GO:0019767	IgE receptor activity(GO:0019767)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0030280	structural constituent of epidermis(GO:0030280)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	1.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	1.9	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	1.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	3.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	2.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	1.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.9	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	1.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	2.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	3.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.7	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.6	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.9	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery

Results for Spdef

Z-value: 1.07

Motif logo

Transcription factors associated with Spdef

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Spdef motif across conditions

Conditions sorted by the z-value of the Spdef motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: