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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Tal1

Z-value: 43.90

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Transcription factors associated with Tal1

Gene Symbol	Gene ID	Gene Info
Tal1 Ensembl NCBI MGI UniProt	ENSMUSG00000028717.6	T cell acute lymphocytic leukemia 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_115048309_115048475	Tal1	8034	0.155966	0.95	3.7e-28	Click!
chr4_115059412_115059621	Tal1	8	0.972150	0.92	2.6e-23	Click!
chr4_115056446_115056861	Tal1	227	0.915348	0.92	8.8e-23	Click!
chr4_115047820_115048056	Tal1	8488	0.154697	0.92	1.3e-22	Click!
chr4_115057189_115057563	Tal1	62	0.967778	0.89	8.4e-20	Click!

Activity of the Tal1 motif across conditions

Conditions sorted by the z-value of the Tal1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_29815389_29815572	284.38	Eml6	echinoderm microtubule associated protein like 6	6182	0.16
chr11_32245695_32246028	256.32	Nprl3	nitrogen permease regulator-like 3	4317	0.12
chr7_80208686_80209443	251.95	Gm45206	predicted gene 45206	330	0.78
chr12_88984393_88984775	242.12	Nrxn3	neurexin III	31185	0.23
chr14_46539820_46540205	234.50	E130120K24Rik	RIKEN cDNA E130120K24 gene	16291	0.12
chr5_23922914_23923135	230.92	Fam126a	family with sequence similarity 126, member A	120	0.95
chr11_31831386_31831912	225.58	Gm12107	predicted gene 12107	1011	0.55
chr6_67161663_67162061	224.57	A430010J10Rik	RIKEN cDNA A430010J10 gene	3062	0.22
chr3_30765691_30766002	222.91	Samd7	sterile alpha motif domain containing 7	9624	0.14
chr8_105820906_105821324	222.88	Ranbp10	RAN binding protein 10	6090	0.09
chr12_110974333_110974713	219.76	Ankrd9	ankyrin repeat domain 9	3732	0.14
chr16_56071732_56071993	217.92	Gm24047	predicted gene, 24047	1299	0.31
chr6_70727412_70727666	217.52	Igkj5	immunoglobulin kappa joining 5	3653	0.15
chrX_162679005_162679180	215.81	Gm15203	predicted gene 15203	85	0.96
chr15_93372828_93373012	215.48	Zcrb1	zinc finger CCHC-type and RNA binding motif 1	15224	0.16
chr15_103251687_103251873	214.16	Nfe2	nuclear factor, erythroid derived 2	93	0.94
chr5_52712758_52713046	212.97	Pi4k2b	phosphatidylinositol 4-kinase type 2 beta	28672	0.15
chr12_76673740_76674235	212.30	Sptb	spectrin beta, erythrocytic	36036	0.15
chr4_134981994_134982157	209.96	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	51065	0.11
chr15_97379586_97379766	209.25	Pced1b	PC-esterase domain containing 1B	18459	0.24
chr13_101611824_101612000	208.50	Gm29341	predicted gene 29341	5679	0.22
chr11_102365077_102365683	206.30	Slc4a1	solute carrier family 4 (anion exchanger), member 1	100	0.94
chr8_23054025_23054342	205.66	Ank1	ankyrin 1, erythroid	4076	0.2
chr6_58642386_58642566	204.93	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	1894	0.39
chr1_33630885_33631502	204.42	Prim2	DNA primase, p58 subunit	7869	0.14
chr15_5658919_5659100	204.30	Gm18715	predicted gene, 18715	55025	0.14
chr1_127756612_127756781	204.29	Acmsd	amino carboxymuconate semialdehyde decarboxylase	61	0.97
chr13_95679618_95679929	204.09	Iqgap2	IQ motif containing GTPase activating protein 2	2551	0.2
chr5_22348437_22348700	203.29	Reln	reelin	3866	0.17
chr14_32146198_32146521	202.80	Msmb	beta-microseminoprotein	1228	0.33
chr18_32542304_32542816	201.13	Gypc	glycophorin C	7142	0.21
chr1_55946905_55947229	200.96	Gm36986	predicted gene, 36986	13689	0.22
chr11_4553637_4553951	199.96	Mtmr3	myotubularin related protein 3	7526	0.17
chr13_83344551_83344924	198.52	Gm48156	predicted gene, 48156	155028	0.04
chr10_11323594_11323775	197.08	Gm48666	predicted gene, 48666	6731	0.15
chr12_111517954_111518283	196.45	Gm40578	predicted gene, 40578	17278	0.1
chrX_140953732_140953903	196.24	Psmd10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	2872	0.24
chr19_60386923_60387224	195.56	Prlhr	prolactin releasing hormone receptor	81231	0.09
chr15_80910888_80911184	193.87	Tnrc6b	trinucleotide repeat containing 6b	4880	0.17
chr14_60654080_60654264	193.53	Spata13	spermatogenesis associated 13	19417	0.21
chr16_48252848_48253236	193.38	Gm49770	predicted gene, 49770	8772	0.18
chr7_99594452_99594625	192.73	Arrb1	arrestin, beta 1	55	0.96
chr13_20150160_20150481	191.86	Elmo1	engulfment and cell motility 1	34887	0.21
chr5_96951661_96952003	190.58	Gm43144	predicted gene 43144	11535	0.1
chr15_93372582_93372767	189.69	Zcrb1	zinc finger CCHC-type and RNA binding motif 1	15470	0.16
chr7_115830920_115831237	189.44	Sox6	SRY (sex determining region Y)-box 6	6368	0.31
chr15_34983305_34983512	189.19	Stk3	serine/threonine kinase 3	16514	0.26
chr12_76670569_76670894	189.05	Sptb	spectrin beta, erythrocytic	39292	0.14
chr5_151418628_151418887	188.04	Gm42906	predicted gene 42906	9406	0.16
chr7_75830381_75830681	186.53	Klhl25	kelch-like 25	17779	0.18
chr6_148603565_148603734	184.94	Gm6313	predicted gene 6313	6084	0.21
chr14_63062234_63062642	183.78	Defb42	defensin beta 42	7365	0.12
chr8_128688649_128689204	182.55	Itgb1	integrin beta 1 (fibronectin receptor beta)	3056	0.24
chr11_117797537_117797802	182.43	6030468B19Rik	RIKEN cDNA 6030468B19 gene	9	0.94
chr2_181419480_181419646	182.11	Zbtb46	zinc finger and BTB domain containing 46	4825	0.11
chr2_164760159_164760320	181.81	Dnttip1	deoxynucleotidyltransferase, terminal, interacting protein 1	6100	0.08
chr3_116859439_116859612	181.19	Frrs1	ferric-chelate reductase 1	42	0.96
chr10_95569556_95569732	179.81	Nudt4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	5498	0.14
chr2_121037044_121037214	179.77	Epb42	erythrocyte membrane protein band 4.2	57	0.95
chr2_28602260_28602441	179.06	Gm22824	predicted gene, 22824	5845	0.11
chr18_77704753_77705042	179.06	8030462N17Rik	RIKEN cDNA 8030462N17 gene	9036	0.14
chr13_95671451_95671789	178.93	Iqgap2	IQ motif containing GTPase activating protein 2	101	0.96
chr2_158141871_158142558	178.42	Tgm2	transglutaminase 2, C polypeptide	2478	0.23
chr1_157695278_157695646	178.32	Gm38213	predicted gene, 38213	73326	0.09
chrX_101287598_101287912	178.25	Med12	mediator complex subunit 12	1731	0.2
chr7_123462053_123462460	176.40	Aqp8	aquaporin 8	35	0.98
chr7_128854662_128855004	176.38	Gm25778	predicted gene, 25778	28486	0.15
chr5_96989015_96989192	175.81	Gm9484	predicted gene 9484	8261	0.13
chr9_58657759_58658148	175.36	Rec114	REC114 meiotic recombination protein	1339	0.42
chr7_133698079_133698264	175.05	Uros	uroporphyrinogen III synthase	91	0.95
chr4_93481257_93481600	174.65	Gm23443	predicted gene, 23443	63849	0.13
chr8_120371766_120372131	174.44	Gm22715	predicted gene, 22715	71601	0.09
chr7_120875272_120875461	174.35	Gm15774	predicted gene 15774	68	0.93
chr8_122286979_122287274	174.26	Zfpm1	zinc finger protein, multitype 1	4985	0.17
chr4_151960522_151960830	174.18	Dnajc11	DnaJ heat shock protein family (Hsp40) member C11	3533	0.16
chr13_59814367_59814542	173.37	Tut7	terminal uridylyl transferase 7	4948	0.12
chr19_32476101_32476290	173.33	Minpp1	multiple inositol polyphosphate histidine phosphatase 1	9574	0.14
chr5_115267246_115267406	172.20	Gm13831	predicted gene 13831	4233	0.09
chr17_83651316_83651614	171.87	Kcng3	potassium voltage-gated channel, subfamily G, member 3	19570	0.22
chr11_105366062_105366358	171.87	Gm11638	predicted gene 11638	2958	0.23
chr11_102363647_102363997	171.79	Slc4a1	solute carrier family 4 (anion exchanger), member 1	118	0.93
chr15_62159095_62159287	171.42	Pvt1	Pvt1 oncogene	18984	0.25
chr11_31861192_31861524	171.30	Cpeb4	cytoplasmic polyadenylation element binding protein 4	10853	0.19
chr6_38341755_38341991	171.20	Zc3hav1	zinc finger CCCH type, antiviral 1	12400	0.13
chr4_46854042_46854371	171.13	Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	5696	0.29
chr7_100844413_100844706	170.99	Relt	RELT tumor necrosis factor receptor	10870	0.14
chr14_69318389_69318982	170.57	Gm16677	predicted gene, 16677	18397	0.08
chr10_62342649_62342920	170.53	Hk1	hexokinase 1	62	0.96
chr3_19650569_19650855	170.32	Trim55	tripartite motif-containing 55	6204	0.16
chr17_48272064_48272554	170.19	Treml4	triggering receptor expressed on myeloid cells-like 4	130	0.94
chr5_149649169_149649529	169.99	Gm20005	predicted gene, 20005	7739	0.14
chr8_33734991_33735310	169.84	Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)	1707	0.27
chr15_56623570_56623885	169.81	Has2os	hyaluronan synthase 2, opposite strand	66217	0.12
chr16_12697258_12697682	169.47	Gm38619	predicted gene, 38619	6898	0.28
chr17_25089285_25089469	169.42	Ift140	intraflagellar transport 140	1294	0.29
chr15_78922683_78922995	169.07	Lgals1	lectin, galactose binding, soluble 1	3886	0.09
chr10_63272949_63273252	169.03	Gm47615	predicted gene, 47615	3010	0.16
chr18_61960597_61960886	168.76	Sh3tc2	SH3 domain and tetratricopeptide repeats 2	7657	0.21
chr13_99108120_99108286	168.72	Gm807	predicted gene 807	7442	0.18
chr19_6132479_6132770	168.47	Snx15	sorting nexin 15	4320	0.07
chr16_36062065_36062536	168.35	Fam162a	family with sequence similarity 162, member A	9069	0.11
chr3_84772122_84772299	168.13	Fbxw7	F-box and WD-40 domain protein 7	43058	0.17
chr2_119605466_119605626	168.05	Oip5os1	Opa interacting protein 5, opposite strand 1	11243	0.1
chr6_86077923_86078088	167.91	Add2	adducin 2 (beta)	52	0.96
chr9_124138054_124138419	167.58	Ccr5	chemokine (C-C motif) receptor 5	9488	0.21
chr1_43414347_43414515	167.47	Gm29041	predicted gene 29041	4847	0.23
chr10_17590195_17590550	167.15	Gm47770	predicted gene, 47770	63458	0.1
chr3_103196500_103196848	166.97	2410024N13Rik	RIKEN cDNA 2410024N13 gene	2301	0.22
chr5_147441974_147442285	166.42	Gm42883	predicted gene 42883	2739	0.14
chr5_105565875_105566288	166.08	Lrrc8c	leucine rich repeat containing 8 family, member C	7223	0.2
chr10_41209082_41209401	165.81	Gm25526	predicted gene, 25526	6804	0.21
chr8_123988622_123988985	165.08	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	5681	0.11
chr11_4543369_4543542	165.07	Mtmr3	myotubularin related protein 3	2813	0.24
chr14_69304834_69305018	164.55	Synb	syncytin b	10627	0.09
chr14_69523086_69523268	164.54	Gm27179	predicted gene 27179	10628	0.1
chr8_68606713_68606995	163.86	Gm15654	predicted gene 15654	13284	0.25
chr4_93583749_93583913	163.70	Gm12640	predicted gene 12640	15355	0.19
chr9_64044981_64045602	163.42	Gm25606	predicted gene, 25606	3205	0.17
chr18_21283772_21283949	163.34	Garem1	GRB2 associated regulator of MAPK1 subtype 1	16263	0.17
chr19_17323425_17323682	162.97	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	11883	0.21
chr14_47522434_47522734	162.78	Fbxo34	F-box protein 34	3495	0.15
chr2_28598073_28598473	162.75	Gm22675	predicted gene, 22675	3146	0.14
chr1_161894692_161894863	162.44	Gm31925	predicted gene, 31925	2630	0.23
chr10_93143358_93143676	162.38	Cdk17	cyclin-dependent kinase 17	17358	0.17
chr17_84776723_84776893	162.10	Lrpprc	leucine-rich PPR-motif containing	735	0.64
chr15_73212141_73212465	161.92	Ptk2	PTK2 protein tyrosine kinase 2	2812	0.25
chr3_108096711_108096990	161.70	Gnat2	guanine nucleotide binding protein, alpha transducing 2	393	0.71
chr4_109445455_109445982	161.34	Ttc39a	tetratricopeptide repeat domain 39A	24776	0.14
chr5_120136253_120136600	161.06	Gm10390	predicted gene 10390	2835	0.27
chr16_34031697_34031893	160.93	Kalrn	kalirin, RhoGEF kinase	15301	0.19
chr1_191855569_191855746	160.69	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	28509	0.11
chr2_103893863_103894037	160.47	Gm13876	predicted gene 13876	5626	0.13
chr3_144670267_144670456	159.90	Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	27106	0.13
chr3_127889681_127889845	159.83	Fam241a	family with sequence similarity 241, member A	6525	0.13
chr7_103877202_103877483	159.50	Olfr66	olfactory receptor 66	4899	0.07
chr16_90988770_90988947	159.44	Gm15965	predicted gene 15965	4951	0.12
chr5_75460472_75460800	159.32	Gm42800	predicted gene 42800	61264	0.11
chr18_15345573_15345724	159.23	A830021F12Rik	RIKEN cDNA A830021F12 gene	6286	0.21
chr15_36321999_36322330	158.60	Rpl7a-ps3	ribosomal protein L7A, pseudogene 3	13220	0.12
chr15_83423666_83423948	158.49	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	17	0.97
chr14_45653782_45654098	158.30	Ddhd1	DDHD domain containing 1	3420	0.14
chr18_34516209_34516494	158.25	n-R5s24	nuclear encoded rRNA 5S 24	6614	0.15
chr9_22453602_22453960	158.19	Gm17545	predicted gene, 17545	509	0.68
chr4_24644850_24645009	157.88	Klhl32	kelch-like 32	30498	0.21
chr2_167043430_167043751	157.72	Znfx1	zinc finger, NFX1-type containing 1	95	0.93
chr14_47321701_47321992	157.38	Gm49190	predicted gene, 49190	790	0.44
chr4_116193969_116194265	157.24	Llph-ps1	LLP homolog, pseudogene 1	6835	0.1
chr9_43234311_43234858	156.87	Oaf	out at first homolog	5327	0.16
chr6_5291230_5291963	156.62	Pon2	paraoxonase 2	2528	0.26
chr18_25097087_25097280	156.45	Fhod3	formin homology 2 domain containing 3	27178	0.22
chr6_70730875_70731236	156.03	Igkj5	immunoglobulin kappa joining 5	7169	0.13
chr13_99019946_99020104	155.89	A930014D07Rik	RIKEN cDNA A930014D07 gene	12926	0.12
chr1_58954126_58954299	155.62	Trak2	trafficking protein, kinesin binding 2	7875	0.16
chr16_97006668_97006833	155.46	Gm32432	predicted gene, 32432	87993	0.09
chr1_154033942_154034127	155.22	Gm28286	predicted gene 28286	267	0.91
chr9_14369323_14369628	155.16	Endod1	endonuclease domain containing 1	11508	0.12
chr2_33843200_33843519	155.00	Nron	non-protein coding RNA, repressor of NFAT	37500	0.15
chr11_121239715_121240038	154.72	Narf	nuclear prelamin A recognition factor	2623	0.17
chr17_33713331_33713621	153.97	Marchf2	membrane associated ring-CH-type finger 2	95	0.94
chr12_55051961_55052112	153.90	2700097O09Rik	RIKEN cDNA 2700097O09 gene	2065	0.2
chr16_31598355_31598677	153.85	Gm34256	predicted gene, 34256	5296	0.18
chr4_148204076_148204384	153.78	Fbxo2	F-box protein 2	43609	0.08
chr3_131728746_131728905	153.07	Gm29865	predicted gene, 29865	30980	0.22
chr16_91441869_91442151	153.01	Gm46562	predicted gene, 46562	16411	0.09
chr9_67024874_67025223	152.87	Tpm1	tropomyosin 1, alpha	7777	0.18
chr4_109411064_109411374	152.72	Ttc39a	tetratricopeptide repeat domain 39A	3557	0.19
chr15_82184037_82184673	152.56	Gm49502	predicted gene, 49502	1161	0.29
chr10_100574875_100575154	152.52	Gm47956	predicted gene, 47956	2412	0.2
chr10_42265100_42265393	152.38	Foxo3	forkhead box O3	6880	0.27
chr11_85339500_85339819	152.33	Bcas3	breast carcinoma amplified sequence 3	13508	0.19
chr4_59533305_59533500	152.30	Gm12529	predicted gene 12529	655	0.67
chr4_42867543_42867734	152.09	Fam205c	family with sequence similarity 205, member C	6083	0.14
chr1_73072668_73072833	151.88	1700027A15Rik	RIKEN cDNA 1700027A15 gene	48181	0.15
chr12_80778227_80778545	151.56	Gm47941	predicted gene, 47941	11957	0.12
chr12_111443494_111443821	151.29	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	667	0.58
chr7_127767294_127767484	151.15	Orai3	ORAI calcium release-activated calcium modulator 3	2426	0.11
chrX_164164755_164165040	151.01	Ace2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	2719	0.26
chr11_95011990_95012348	150.97	Samd14	sterile alpha motif domain containing 14	1888	0.21
chr11_16503276_16503437	150.96	Sec61g	SEC61, gamma subunit	1688	0.39
chr19_8603137_8603306	150.96	Slc22a8	solute carrier family 22 (organic anion transporter), member 8	11932	0.1
chrX_85614770_85615135	150.75	Gm44378	predicted gene, 44378	25975	0.18
chr8_121899242_121899545	150.60	Slc7a5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	2891	0.15
chr8_122309305_122309664	150.47	Zfpm1	zinc finger protein, multitype 1	2164	0.24
chr16_58454803_58455144	150.45	Dcbld2	discoidin, CUB and LCCL domain containing 2	218	0.94
chr9_64590624_64590805	150.36	Megf11	multiple EGF-like-domains 11	43815	0.17
chr14_69321815_69322332	150.09	Gm16677	predicted gene, 16677	15009	0.09
chr14_69540059_69540582	150.04	Gm27174	predicted gene 27174	15012	0.09
chr19_37238054_37238331	149.96	Gm25268	predicted gene, 25268	4708	0.16
chr16_21996984_21997165	149.13	Liph	lipase, member H	1411	0.37
chr8_119918152_119918328	149.13	Usp10	ubiquitin specific peptidase 10	7383	0.17
chr13_75733796_75734110	149.04	Gm48302	predicted gene, 48302	6674	0.14
chr16_49800061_49800448	148.98	Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	279	0.89
chr14_20599676_20599956	148.96	Usp54	ubiquitin specific peptidase 54	5514	0.13
chr3_102165876_102166166	148.90	Vangl1	VANGL planar cell polarity 1	81	0.96
chr6_29701091_29701386	148.81	Tspan33	tetraspanin 33	6790	0.18
chr13_44663056_44663676	148.76	Gm47805	predicted gene, 47805	41184	0.16
chr3_105808565_105808856	148.53	Gm5547	predicted gene 5547	6830	0.11
chr3_142884736_142884993	148.37	9530052C20Rik	RIKEN cDNA 9530052C20 gene	2369	0.19
chr7_100466963_100467472	148.33	Gm10603	predicted gene 10603	27	0.95
chr14_69536637_69537045	148.24	Gm27174	predicted gene 27174	18491	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tal1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
103.0	411.9	GO:0019805	quinolinate biosynthetic process(GO:0019805)
99.4	497.0	GO:0015722	canalicular bile acid transport(GO:0015722)
96.0	384.0	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
93.0	278.9	GO:0060375	regulation of mast cell differentiation(GO:0060375)
84.0	251.9	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
83.7	251.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
80.3	80.3	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
71.5	286.2	GO:0008228	opsonization(GO:0008228)
66.9	133.8	GO:0090579	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
65.2	260.9	GO:0070836	caveola assembly(GO:0070836)
64.7	194.2	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
63.7	127.4	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
62.9	314.3	GO:0072488	ammonium transmembrane transport(GO:0072488)
62.7	313.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
61.0	305.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
60.8	364.7	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
59.6	238.2	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
55.4	1164.4	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
55.4	277.0	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
54.7	218.7	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
54.0	161.9	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
53.3	266.4	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
53.2	159.6	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
52.8	211.1	GO:0050904	diapedesis(GO:0050904)
52.6	262.8	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
51.5	463.4	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
50.9	458.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
50.6	101.2	GO:0018992	germ-line sex determination(GO:0018992)
49.8	199.4	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
48.2	96.5	GO:0048388	endosomal lumen acidification(GO:0048388)
46.7	186.8	GO:0023021	termination of signal transduction(GO:0023021)
46.0	138.0	GO:0018343	protein farnesylation(GO:0018343)
46.0	229.8	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
45.5	182.0	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
45.3	45.3	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
45.3	90.7	GO:0048194	Golgi vesicle budding(GO:0048194)
45.2	135.7	GO:0035973	aggrephagy(GO:0035973)
44.4	133.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
43.4	217.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
43.1	43.1	GO:0012502	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
42.9	128.6	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
42.6	170.5	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
42.6	170.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
42.5	42.5	GO:0006680	glucosylceramide catabolic process(GO:0006680)
42.3	169.2	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
41.4	41.4	GO:0031047	gene silencing by RNA(GO:0031047)
41.2	123.5	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
41.0	163.8	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
40.5	202.4	GO:0047484	regulation of response to osmotic stress(GO:0047484)
40.2	321.3	GO:0060352	cell adhesion molecule production(GO:0060352)
39.9	79.8	GO:1990705	cholangiocyte proliferation(GO:1990705)
39.9	159.5	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
39.1	117.4	GO:0070627	ferrous iron import(GO:0070627)
39.0	117.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
38.6	38.6	GO:0046349	amino sugar biosynthetic process(GO:0046349)
38.6	38.6	GO:0032808	lacrimal gland development(GO:0032808)
38.3	38.3	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
38.2	114.5	GO:0036066	protein O-linked fucosylation(GO:0036066)
38.1	152.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
38.0	228.2	GO:0002457	T cell antigen processing and presentation(GO:0002457)
38.0	38.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
37.9	75.7	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
37.8	113.5	GO:0006741	NADP biosynthetic process(GO:0006741)
37.8	75.6	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
37.8	37.8	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
37.7	75.5	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
37.7	188.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
37.5	225.2	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
37.4	149.5	GO:0006499	N-terminal protein myristoylation(GO:0006499)
37.4	224.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
37.2	148.9	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
37.0	592.3	GO:0046685	response to arsenic-containing substance(GO:0046685)
36.9	147.4	GO:2000574	regulation of microtubule motor activity(GO:2000574)
36.8	110.4	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
36.5	36.5	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
36.3	218.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
36.3	761.6	GO:0048821	erythrocyte development(GO:0048821)
36.0	647.9	GO:0001574	ganglioside biosynthetic process(GO:0001574)
35.9	179.3	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
35.8	35.8	GO:0007431	salivary gland development(GO:0007431)
35.4	176.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
35.4	106.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
35.1	105.2	GO:0021553	olfactory nerve development(GO:0021553)
35.0	70.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
34.5	137.9	GO:0032264	IMP salvage(GO:0032264)
33.8	169.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
33.5	100.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
33.2	33.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
33.0	66.0	GO:0001543	ovarian follicle rupture(GO:0001543)
33.0	131.9	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
32.8	65.7	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
32.6	130.4	GO:0007290	spermatid nucleus elongation(GO:0007290)
32.6	65.1	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
32.5	97.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
32.4	97.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
31.9	223.2	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
31.7	126.9	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
31.7	95.2	GO:1903416	response to glycoside(GO:1903416)
31.7	95.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
31.7	95.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
31.7	158.4	GO:0015879	carnitine transport(GO:0015879)
31.7	221.6	GO:0043320	natural killer cell degranulation(GO:0043320)
31.6	189.5	GO:0010815	bradykinin catabolic process(GO:0010815)
31.3	125.4	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
31.2	125.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
31.0	93.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
30.8	123.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
30.4	91.2	GO:0001555	oocyte growth(GO:0001555)
30.2	120.7	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
29.8	89.3	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
29.7	89.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
29.6	118.3	GO:0071918	urea transmembrane transport(GO:0071918)
29.4	29.4	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
29.3	117.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
29.1	58.2	GO:0046618	drug export(GO:0046618)
28.8	86.4	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
28.8	86.3	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
28.7	286.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
28.6	57.1	GO:0032898	neurotrophin production(GO:0032898)
28.5	85.4	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
28.4	85.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
28.3	84.8	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
28.2	140.9	GO:0046485	ether lipid metabolic process(GO:0046485)
27.8	111.4	GO:0061113	pancreas morphogenesis(GO:0061113)
27.7	110.9	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
27.4	109.7	GO:0070669	response to interleukin-2(GO:0070669)
27.3	136.7	GO:0009642	response to light intensity(GO:0009642)
27.2	190.5	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
27.2	81.6	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
27.2	108.7	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
27.1	135.4	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
26.9	134.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
26.9	268.8	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
26.8	214.1	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
26.6	133.2	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
26.3	131.5	GO:0015671	oxygen transport(GO:0015671)
26.1	52.1	GO:0008050	female courtship behavior(GO:0008050)
26.0	78.1	GO:0021699	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
25.9	51.8	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
25.9	103.4	GO:0030916	otic vesicle formation(GO:0030916)
25.5	25.5	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
25.4	25.4	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
25.3	151.8	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
25.2	100.9	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
25.1	50.2	GO:0032782	bile acid secretion(GO:0032782)
25.1	75.2	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
25.1	225.5	GO:0018206	peptidyl-methionine modification(GO:0018206)
25.0	224.8	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
24.9	99.7	GO:0072675	osteoclast fusion(GO:0072675)
24.8	99.3	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
24.8	49.5	GO:0043173	nucleotide salvage(GO:0043173)
24.7	74.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
24.7	49.4	GO:0043379	memory T cell differentiation(GO:0043379)
24.7	24.7	GO:0003091	renal water homeostasis(GO:0003091)
24.6	49.3	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
24.4	97.8	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
24.4	73.3	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
24.4	73.2	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
24.2	48.4	GO:0042908	xenobiotic transport(GO:0042908)
24.2	169.2	GO:0045332	phospholipid translocation(GO:0045332)
24.0	24.0	GO:0010172	embryonic body morphogenesis(GO:0010172)
24.0	383.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
23.9	95.8	GO:0035405	histone-threonine phosphorylation(GO:0035405)
23.7	47.4	GO:0051964	negative regulation of synapse assembly(GO:0051964)
23.7	71.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
23.6	94.3	GO:0021943	formation of radial glial scaffolds(GO:0021943)
23.5	70.6	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
23.3	419.2	GO:0006144	purine nucleobase metabolic process(GO:0006144)
23.3	69.8	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
23.2	139.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
23.1	46.3	GO:0070827	chromatin maintenance(GO:0070827)
23.0	69.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
23.0	344.7	GO:0006828	manganese ion transport(GO:0006828)
22.9	45.8	GO:0007386	compartment pattern specification(GO:0007386)
22.9	22.9	GO:0044532	modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) modulation by symbiont of host programmed cell death(GO:0052040) modulation by symbiont of host apoptotic process(GO:0052150) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433)
22.5	67.4	GO:0061511	centriole elongation(GO:0061511)
22.5	67.4	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
22.4	44.9	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
22.4	89.5	GO:0015705	iodide transport(GO:0015705)
22.3	111.7	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
22.1	88.6	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
22.1	66.4	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
22.0	263.9	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
22.0	22.0	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
21.9	65.7	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
21.9	87.6	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
21.9	87.6	GO:0090527	actin filament reorganization(GO:0090527)
21.9	65.7	GO:0019371	cyclooxygenase pathway(GO:0019371)
21.9	43.8	GO:2000978	regulation of forebrain neuron differentiation(GO:2000977) negative regulation of forebrain neuron differentiation(GO:2000978)
21.8	65.5	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
21.8	109.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
21.8	43.5	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
21.7	65.2	GO:0060931	sinoatrial node cell development(GO:0060931)
21.7	21.7	GO:0006114	glycerol biosynthetic process(GO:0006114)
21.7	43.4	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
21.6	64.8	GO:0036394	amylase secretion(GO:0036394)
21.5	21.5	GO:0061515	myeloid cell development(GO:0061515)
21.5	21.5	GO:0010544	negative regulation of platelet activation(GO:0010544)
21.4	42.9	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
21.4	64.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
21.2	63.7	GO:0006481	C-terminal protein methylation(GO:0006481)
21.1	42.3	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
21.1	42.3	GO:0036258	multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
21.0	42.1	GO:0043309	regulation of eosinophil degranulation(GO:0043309)
20.9	41.8	GO:0051293	establishment of spindle localization(GO:0051293)
20.9	41.8	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
20.8	186.8	GO:0031507	heterochromatin assembly(GO:0031507)
20.7	145.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
20.7	62.0	GO:1902065	response to L-glutamate(GO:1902065)
20.6	103.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
20.6	61.7	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
20.4	142.8	GO:0046085	adenosine metabolic process(GO:0046085)
20.4	61.2	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
20.3	121.7	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
20.3	40.5	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
20.2	121.5	GO:0060263	regulation of respiratory burst(GO:0060263)
20.2	80.7	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
20.1	40.3	GO:1901563	response to camptothecin(GO:1901563)
20.0	40.0	GO:0046874	quinolinate metabolic process(GO:0046874)
20.0	139.8	GO:0071318	cellular response to ATP(GO:0071318)
20.0	79.9	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
19.8	59.5	GO:0006624	vacuolar protein processing(GO:0006624)
19.8	59.4	GO:0018199	peptidyl-glutamine modification(GO:0018199)
19.7	39.4	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
19.7	78.6	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
19.5	39.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
19.4	77.8	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
19.4	58.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
19.4	38.8	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
19.3	58.0	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
19.3	115.8	GO:0042866	pyruvate biosynthetic process(GO:0042866)
19.3	19.3	GO:0032006	regulation of TOR signaling(GO:0032006)
19.2	38.4	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
19.2	76.7	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
19.2	38.3	GO:0055099	response to high density lipoprotein particle(GO:0055099)
19.0	38.1	GO:0042733	embryonic digit morphogenesis(GO:0042733)
19.0	95.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
19.0	38.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
19.0	57.0	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
19.0	94.9	GO:0016266	O-glycan processing(GO:0016266)
18.9	75.8	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
18.6	37.3	GO:0070487	monocyte aggregation(GO:0070487)
18.5	55.5	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
18.5	18.5	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
18.4	184.3	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
18.4	128.8	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
18.4	55.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
18.3	73.0	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
18.2	36.4	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
18.2	54.5	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069) glandular epithelial cell maturation(GO:0002071)
18.1	36.3	GO:0034472	snRNA 3'-end processing(GO:0034472)
18.1	108.8	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
18.1	72.4	GO:0051697	protein delipidation(GO:0051697)
18.1	18.1	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
18.1	36.2	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
18.0	90.0	GO:0040016	embryonic cleavage(GO:0040016)
17.9	179.4	GO:0051292	nuclear pore complex assembly(GO:0051292)
17.9	161.0	GO:0071361	cellular response to ethanol(GO:0071361)
17.9	17.9	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
17.8	71.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
17.8	71.3	GO:0006004	fucose metabolic process(GO:0006004)
17.8	53.5	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
17.8	35.5	GO:0072718	response to cisplatin(GO:0072718)
17.8	17.8	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
17.7	124.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
17.7	88.5	GO:0006572	tyrosine catabolic process(GO:0006572)
17.7	159.2	GO:0008343	adult feeding behavior(GO:0008343)
17.7	53.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
17.7	35.3	GO:0043101	purine-containing compound salvage(GO:0043101)
17.7	17.7	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
17.6	35.2	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
17.6	123.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
17.6	333.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
17.5	17.5	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
17.5	105.1	GO:0007220	Notch receptor processing(GO:0007220)
17.5	87.3	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
17.4	86.9	GO:0036233	glycine import(GO:0036233)
17.3	69.3	GO:0003383	apical constriction(GO:0003383)
17.2	17.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
17.2	51.6	GO:0002572	pro-T cell differentiation(GO:0002572)
17.2	86.0	GO:0015816	glycine transport(GO:0015816)
17.1	85.6	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
17.1	34.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
17.1	188.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
17.1	34.2	GO:0061687	detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
17.1	51.3	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
17.0	51.0	GO:0000087	mitotic M phase(GO:0000087)
16.9	33.9	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
16.9	33.8	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
16.9	67.5	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
16.9	50.7	GO:0040031	snRNA modification(GO:0040031)
16.9	67.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
16.9	168.8	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
16.9	67.4	GO:0001887	selenium compound metabolic process(GO:0001887)
16.9	50.6	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
16.8	134.8	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
16.8	50.5	GO:0034214	protein hexamerization(GO:0034214)
16.8	50.5	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
16.8	83.8	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
16.7	33.4	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
16.6	16.6	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
16.6	49.8	GO:1900368	regulation of RNA interference(GO:1900368)
16.6	82.8	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
16.6	198.7	GO:0021819	layer formation in cerebral cortex(GO:0021819)
16.5	66.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
16.5	115.8	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
16.5	49.6	GO:0009946	proximal/distal axis specification(GO:0009946)
16.5	16.5	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
16.5	115.2	GO:0021860	pyramidal neuron development(GO:0021860)
16.4	115.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
16.4	49.3	GO:0021564	vagus nerve development(GO:0021564)
16.4	49.2	GO:0031049	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
16.4	81.8	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
16.3	48.8	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
16.3	81.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
16.2	113.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
16.2	32.4	GO:0042126	nitrate metabolic process(GO:0042126)
16.2	48.5	GO:0034729	histone H3-K79 methylation(GO:0034729)
16.1	80.7	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
16.1	64.5	GO:0018101	protein citrullination(GO:0018101)
16.1	112.9	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
16.0	96.2	GO:0006561	proline biosynthetic process(GO:0006561)
16.0	31.9	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
15.9	47.7	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
15.9	127.2	GO:0009437	carnitine metabolic process(GO:0009437)
15.9	349.7	GO:0032007	negative regulation of TOR signaling(GO:0032007)
15.9	190.5	GO:0032310	prostaglandin secretion(GO:0032310)
15.8	47.5	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
15.8	31.6	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
15.8	78.9	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
15.8	31.5	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
15.7	15.7	GO:0030279	negative regulation of ossification(GO:0030279)
15.7	31.5	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
15.7	31.3	GO:0051660	establishment of centrosome localization(GO:0051660)
15.7	31.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
15.6	31.3	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
15.6	46.9	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
15.6	109.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
15.6	31.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
15.6	311.1	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
15.4	46.3	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
15.3	92.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
15.3	45.8	GO:0046208	spermine catabolic process(GO:0046208)
15.3	15.3	GO:0035330	regulation of hippo signaling(GO:0035330)
15.2	60.9	GO:0090435	protein localization to nuclear envelope(GO:0090435)
15.2	45.7	GO:1904431	positive regulation of t-circle formation(GO:1904431)
15.1	60.6	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
15.1	15.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
15.1	60.6	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
15.1	30.2	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
15.1	30.1	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
15.1	105.5	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
15.0	150.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
14.9	29.9	GO:1902075	cellular response to salt(GO:1902075)
14.9	119.3	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
14.9	44.7	GO:0019532	oxalate transport(GO:0019532)
14.9	44.6	GO:0006982	response to lipid hydroperoxide(GO:0006982)
14.8	59.2	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
14.8	14.8	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
14.7	147.2	GO:0090330	regulation of platelet aggregation(GO:0090330)
14.7	102.9	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
14.7	44.0	GO:0036438	maintenance of lens transparency(GO:0036438)
14.7	308.2	GO:0019432	triglyceride biosynthetic process(GO:0019432)
14.7	29.3	GO:0090168	Golgi reassembly(GO:0090168)
14.6	117.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
14.6	219.7	GO:0051016	barbed-end actin filament capping(GO:0051016)
14.6	160.5	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
14.6	174.7	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
14.5	421.9	GO:0070527	platelet aggregation(GO:0070527)
14.5	14.5	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
14.5	101.7	GO:0010960	magnesium ion homeostasis(GO:0010960)
14.5	29.0	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
14.5	43.5	GO:0034627	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
14.5	14.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
14.5	43.4	GO:0010624	regulation of Schwann cell proliferation(GO:0010624)
14.5	14.5	GO:0070889	platelet alpha granule organization(GO:0070889)
14.4	14.4	GO:0090231	regulation of spindle checkpoint(GO:0090231)
14.4	43.3	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
14.4	86.3	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
14.4	14.4	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
14.4	129.2	GO:0046835	carbohydrate phosphorylation(GO:0046835)
14.4	43.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
14.3	14.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
14.2	42.7	GO:0046951	ketone body biosynthetic process(GO:0046951)
14.2	28.5	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
14.2	170.5	GO:0051601	exocyst localization(GO:0051601)
14.2	14.2	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
14.2	42.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
14.1	198.0	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
14.1	42.4	GO:0001692	histamine metabolic process(GO:0001692)
14.1	70.6	GO:0071985	multivesicular body sorting pathway(GO:0071985)
14.1	14.1	GO:0034204	lipid translocation(GO:0034204)
14.1	70.3	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
14.0	14.0	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
14.0	98.2	GO:0006778	porphyrin-containing compound metabolic process(GO:0006778)
14.0	14.0	GO:0031860	telomeric 3' overhang formation(GO:0031860)
14.0	98.0	GO:0071850	mitotic cell cycle arrest(GO:0071850)
14.0	28.0	GO:0006068	ethanol catabolic process(GO:0006068)
14.0	28.0	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
14.0	14.0	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
14.0	223.5	GO:0016075	rRNA catabolic process(GO:0016075)
14.0	41.9	GO:0015886	heme transport(GO:0015886)
14.0	335.0	GO:0007029	endoplasmic reticulum organization(GO:0007029)
14.0	69.8	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
14.0	41.9	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683)
13.9	111.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
13.9	41.7	GO:0032202	telomere assembly(GO:0032202)
13.9	83.2	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
13.9	41.6	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
13.8	540.0	GO:0007091	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
13.8	41.4	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
13.7	13.7	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
13.7	137.4	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
13.7	54.8	GO:0006007	glucose catabolic process(GO:0006007)
13.7	82.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
13.6	27.2	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
13.6	13.6	GO:0032466	negative regulation of cytokinesis(GO:0032466)
13.5	27.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
13.5	27.0	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
13.4	13.4	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
13.4	13.4	GO:0035622	intrahepatic bile duct development(GO:0035622)
13.4	120.6	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
13.4	160.7	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
13.4	53.5	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
13.3	66.6	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
13.3	26.6	GO:0070266	necroptotic process(GO:0070266)
13.3	291.8	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
13.3	66.3	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
13.2	39.6	GO:0051464	positive regulation of cortisol secretion(GO:0051464)
13.2	39.5	GO:0006545	glycine biosynthetic process(GO:0006545)
13.2	26.3	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
13.1	13.1	GO:0002125	maternal aggressive behavior(GO:0002125)
13.1	26.3	GO:0006551	leucine metabolic process(GO:0006551)
13.1	13.1	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
13.0	156.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
13.0	26.1	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
13.0	39.1	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
13.0	234.4	GO:0018345	protein palmitoylation(GO:0018345)
13.0	26.0	GO:0032289	central nervous system myelin formation(GO:0032289)
13.0	51.9	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
13.0	51.9	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
13.0	77.8	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
13.0	129.5	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
12.9	12.9	GO:0060700	regulation of ribonuclease activity(GO:0060700)
12.9	25.8	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
12.8	141.1	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
12.8	64.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
12.8	25.6	GO:0070459	prolactin secretion(GO:0070459)
12.8	38.4	GO:0007525	somatic muscle development(GO:0007525)
12.8	140.7	GO:0035455	response to interferon-alpha(GO:0035455)
12.7	140.0	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
12.7	229.0	GO:0006491	N-glycan processing(GO:0006491)
12.7	12.7	GO:0070350	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
12.7	12.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
12.7	25.3	GO:0002215	defense response to nematode(GO:0002215)
12.6	37.9	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
12.6	101.0	GO:0070307	lens fiber cell development(GO:0070307)
12.6	25.2	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
12.6	37.8	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
12.6	37.8	GO:0000966	RNA 5'-end processing(GO:0000966)
12.6	62.9	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
12.5	37.6	GO:0072321	chaperone-mediated protein transport(GO:0072321)
12.5	37.6	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
12.5	12.5	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
12.5	24.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
12.5	137.1	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
12.5	99.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
12.5	149.6	GO:0045070	positive regulation of viral genome replication(GO:0045070)
12.5	74.7	GO:0048227	plasma membrane to endosome transport(GO:0048227)
12.4	37.3	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
12.4	49.8	GO:0070475	rRNA base methylation(GO:0070475)
12.4	62.1	GO:1902969	mitotic DNA replication(GO:1902969)
12.4	24.8	GO:0051409	response to nitrosative stress(GO:0051409)
12.4	24.8	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
12.4	49.6	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
12.4	12.4	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
12.4	24.8	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
12.3	148.1	GO:0000305	response to oxygen radical(GO:0000305)
12.3	61.7	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
12.3	12.3	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
12.3	135.6	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
12.3	37.0	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
12.3	110.8	GO:0090207	regulation of triglyceride metabolic process(GO:0090207)
12.3	24.6	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
12.2	36.7	GO:0051531	NFAT protein import into nucleus(GO:0051531)
12.2	122.3	GO:0006625	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
12.2	280.4	GO:1902808	positive regulation of cell cycle G1/S phase transition(GO:1902808)
12.2	73.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
12.2	36.5	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
12.2	12.2	GO:0032439	endosome localization(GO:0032439)
12.2	60.8	GO:0061635	regulation of protein complex stability(GO:0061635)
12.1	12.1	GO:0055094	response to lipoprotein particle(GO:0055094)
12.1	12.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
12.1	48.3	GO:0050917	sensory perception of umami taste(GO:0050917)
12.0	12.0	GO:0030259	lipid glycosylation(GO:0030259)
12.0	35.9	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
12.0	35.9	GO:0046112	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleobase biosynthetic process(GO:0046112)
12.0	35.9	GO:0007296	vitellogenesis(GO:0007296)
11.9	191.0	GO:0030488	tRNA methylation(GO:0030488)
11.9	23.9	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
11.9	23.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
11.9	83.1	GO:0030575	nuclear body organization(GO:0030575)
11.8	23.7	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
11.8	35.5	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
11.8	23.6	GO:0001920	negative regulation of receptor recycling(GO:0001920)
11.8	59.0	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
11.8	129.6	GO:0055090	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
11.8	105.9	GO:0032801	receptor catabolic process(GO:0032801)
11.8	141.0	GO:0010842	retina layer formation(GO:0010842)
11.7	47.0	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
11.7	199.4	GO:0006471	protein ADP-ribosylation(GO:0006471)
11.7	117.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
11.7	70.2	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
11.7	23.4	GO:0043691	reverse cholesterol transport(GO:0043691)
11.7	23.4	GO:0072611	interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) regulation of interleukin-13 secretion(GO:2000665)
11.7	11.7	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
11.7	23.4	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
11.7	81.7	GO:0031468	nuclear envelope reassembly(GO:0031468)
11.6	58.2	GO:0018904	ether metabolic process(GO:0018904)
11.6	11.6	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
11.6	465.0	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
11.6	23.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
11.6	46.4	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
11.6	57.9	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
11.6	23.1	GO:0086043	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
11.6	11.6	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
11.5	138.2	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
11.5	23.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
11.5	34.4	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990)
11.5	80.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
11.5	34.4	GO:0015889	cobalamin transport(GO:0015889)
11.5	45.8	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
11.5	11.5	GO:0006522	alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078)
11.4	22.9	GO:0019042	viral latency(GO:0019042)
11.4	22.8	GO:1901421	positive regulation of response to alcohol(GO:1901421)
11.4	11.4	GO:0042095	interferon-gamma biosynthetic process(GO:0042095)
11.3	11.3	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
11.3	33.8	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
11.2	56.2	GO:0019695	choline metabolic process(GO:0019695)
11.2	56.2	GO:0001842	neural fold formation(GO:0001842)
11.2	11.2	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
11.2	33.7	GO:0016554	cytidine to uridine editing(GO:0016554)
11.2	22.5	GO:0032570	response to progesterone(GO:0032570)
11.2	44.9	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
11.2	22.4	GO:0034587	piRNA metabolic process(GO:0034587)
11.2	22.4	GO:0071839	apoptotic process in bone marrow(GO:0071839) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
11.2	33.6	GO:0090045	positive regulation of deacetylase activity(GO:0090045) regulation of histone deacetylase activity(GO:1901725)
11.2	11.2	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
11.2	44.7	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
11.2	67.0	GO:0044351	macropinocytosis(GO:0044351)
11.1	33.4	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
11.1	55.5	GO:0015807	L-amino acid transport(GO:0015807)
11.1	122.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
11.1	22.2	GO:2000909	sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909)
11.1	33.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
11.1	132.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
11.1	11.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
11.0	154.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
11.0	11.0	GO:0042359	vitamin D metabolic process(GO:0042359)
11.0	11.0	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
10.9	87.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
10.9	21.8	GO:0046292	formaldehyde metabolic process(GO:0046292)
10.9	76.1	GO:0006670	sphingosine metabolic process(GO:0006670)
10.9	21.7	GO:0071462	cellular response to water stimulus(GO:0071462)
10.9	54.3	GO:0048268	clathrin coat assembly(GO:0048268)
10.8	65.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
10.8	10.8	GO:0021516	dorsal spinal cord development(GO:0021516)
10.8	356.9	GO:0043039	tRNA aminoacylation(GO:0043039)
10.8	108.1	GO:0030149	sphingolipid catabolic process(GO:0030149)
10.8	43.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
10.8	75.6	GO:0070306	lens fiber cell differentiation(GO:0070306)
10.8	140.4	GO:0015858	nucleoside transport(GO:0015858)
10.8	54.0	GO:0042023	DNA endoreduplication(GO:0042023)
10.8	10.8	GO:1902188	positive regulation of viral release from host cell(GO:1902188)
10.8	21.6	GO:1902473	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
10.8	21.5	GO:0051099	positive regulation of binding(GO:0051099)
10.7	139.6	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
10.7	64.3	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
10.7	32.1	GO:0044838	cell quiescence(GO:0044838)
10.6	31.9	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
10.6	31.8	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
10.6	63.6	GO:0007097	nuclear migration(GO:0007097)
10.6	42.3	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154)
10.6	10.6	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
10.6	21.1	GO:2001225	regulation of chloride transport(GO:2001225)
10.5	73.8	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
10.5	105.3	GO:0001675	acrosome assembly(GO:0001675)
10.5	10.5	GO:0043462	regulation of ATPase activity(GO:0043462)
10.5	42.1	GO:0090009	primitive streak formation(GO:0090009)
10.5	209.9	GO:0006301	postreplication repair(GO:0006301)
10.5	21.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
10.5	41.9	GO:1904181	positive regulation of membrane depolarization(GO:1904181)
10.4	41.8	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
10.4	83.5	GO:0046686	response to cadmium ion(GO:0046686)
10.4	31.2	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
10.4	72.8	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
10.4	20.8	GO:0006824	cobalt ion transport(GO:0006824)
10.4	93.4	GO:0008340	determination of adult lifespan(GO:0008340)
10.4	51.9	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
10.4	31.1	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
10.4	31.1	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
10.3	496.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
10.3	31.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
10.3	31.0	GO:0070126	mitochondrial translational termination(GO:0070126)
10.3	10.3	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
10.3	390.4	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
10.3	10.3	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
10.3	51.3	GO:0006528	asparagine metabolic process(GO:0006528)
10.3	10.3	GO:1904177	regulation of adipose tissue development(GO:1904177)
10.3	61.5	GO:0031167	rRNA methylation(GO:0031167)
10.3	82.0	GO:0034498	early endosome to Golgi transport(GO:0034498)
10.2	10.2	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
10.2	20.4	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
10.2	20.4	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
10.2	30.6	GO:1903671	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
10.2	30.5	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
10.2	10.2	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
10.2	122.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
10.2	81.2	GO:0009081	branched-chain amino acid metabolic process(GO:0009081)
10.1	40.6	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
10.1	10.1	GO:0010447	response to acidic pH(GO:0010447)
10.1	91.0	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
10.1	50.5	GO:0060056	mammary gland involution(GO:0060056)
10.1	30.3	GO:2000210	positive regulation of anoikis(GO:2000210)
10.1	50.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
10.1	20.2	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
10.1	10.1	GO:0009124	nucleoside monophosphate biosynthetic process(GO:0009124)
10.1	30.2	GO:0072126	positive regulation of glomerular mesangial cell proliferation(GO:0072126)
10.0	60.3	GO:0043247	telomere maintenance in response to DNA damage(GO:0043247)
10.0	10.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
10.0	19.9	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
10.0	49.8	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
10.0	39.8	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
9.9	29.8	GO:0031577	spindle checkpoint(GO:0031577)
9.9	19.9	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
9.9	49.6	GO:0009650	UV protection(GO:0009650)
9.9	238.2	GO:0006730	one-carbon metabolic process(GO:0006730)
9.9	39.6	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
9.9	19.8	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
9.9	49.3	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
9.8	9.8	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
9.8	19.7	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
9.8	58.9	GO:0032534	regulation of microvillus assembly(GO:0032534)
9.8	49.0	GO:1903392	negative regulation of adherens junction organization(GO:1903392)
9.8	29.3	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
9.8	19.5	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
9.7	29.2	GO:0016126	sterol biosynthetic process(GO:0016126)
9.7	29.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
9.7	9.7	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
9.7	96.6	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
9.7	38.6	GO:0034720	histone H3-K4 demethylation(GO:0034720)
9.6	86.8	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
9.6	9.6	GO:0060982	coronary artery morphogenesis(GO:0060982)
9.6	38.5	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
9.6	9.6	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
9.6	9.6	GO:0048254	snoRNA localization(GO:0048254)
9.6	38.4	GO:0060363	cranial suture morphogenesis(GO:0060363)
9.6	86.4	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
9.6	57.6	GO:0043983	histone H4-K12 acetylation(GO:0043983)
9.6	47.9	GO:0046218	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
9.6	38.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
9.6	9.6	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
9.5	19.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
9.5	66.6	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
9.5	19.0	GO:0001865	NK T cell differentiation(GO:0001865)
9.5	37.9	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
9.5	9.5	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
9.4	75.6	GO:0001771	immunological synapse formation(GO:0001771)
9.4	9.4	GO:2000468	regulation of peroxidase activity(GO:2000468)
9.4	28.3	GO:0006056	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
9.4	226.0	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
9.4	9.4	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
9.4	9.4	GO:0051974	negative regulation of telomerase activity(GO:0051974)
9.4	9.4	GO:0072008	glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
9.4	9.4	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
9.4	337.0	GO:0006611	protein export from nucleus(GO:0006611)
9.3	56.0	GO:1903441	protein localization to ciliary membrane(GO:1903441)
9.3	177.4	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
9.3	37.3	GO:0099515	actin filament-based transport(GO:0099515)
9.3	28.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
9.3	9.3	GO:1904376	negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
9.3	18.6	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
9.3	37.2	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
9.3	18.6	GO:0019676	ammonia assimilation cycle(GO:0019676)
9.3	27.9	GO:0015825	L-serine transport(GO:0015825)
9.3	9.3	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
9.3	9.3	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
9.3	18.6	GO:0016584	nucleosome positioning(GO:0016584)
9.3	18.6	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
9.3	18.5	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
9.3	18.5	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
9.3	9.3	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
9.3	18.5	GO:1904059	regulation of locomotor rhythm(GO:1904059)
9.3	46.3	GO:0051013	microtubule severing(GO:0051013)
9.2	46.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
9.2	55.5	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
9.2	18.5	GO:0045055	regulated exocytosis(GO:0045055)
9.2	92.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
9.2	18.5	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
9.2	18.4	GO:2000674	regulation of type B pancreatic cell apoptotic process(GO:2000674)
9.2	46.1	GO:0046697	decidualization(GO:0046697)
9.2	36.8	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
9.2	18.4	GO:1904705	regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874)
9.2	9.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
9.2	36.6	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
9.2	18.3	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
9.2	54.9	GO:0043117	positive regulation of vascular permeability(GO:0043117)
9.1	200.5	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
9.1	27.3	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
9.1	36.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
9.1	36.4	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
9.1	27.3	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
9.1	54.5	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
9.1	9.1	GO:0010948	negative regulation of cell cycle process(GO:0010948)
9.1	9.1	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
9.1	136.0	GO:0010737	protein kinase A signaling(GO:0010737)
9.0	18.1	GO:0046959	habituation(GO:0046959)
9.0	36.2	GO:0060295	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
9.0	162.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
9.0	9.0	GO:1901536	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
9.0	18.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
9.0	9.0	GO:0015838	amino-acid betaine transport(GO:0015838)
9.0	9.0	GO:0035898	parathyroid hormone secretion(GO:0035898)
9.0	36.0	GO:0048680	positive regulation of axon regeneration(GO:0048680)
9.0	9.0	GO:0016115	terpenoid catabolic process(GO:0016115)
8.9	17.9	GO:1904528	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
8.9	35.8	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
8.9	17.9	GO:0031642	negative regulation of myelination(GO:0031642)
8.9	17.9	GO:1902807	negative regulation of cell cycle G1/S phase transition(GO:1902807)
8.9	8.9	GO:0035510	DNA dealkylation(GO:0035510) demethylation(GO:0070988)
8.9	62.2	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
8.9	133.3	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
8.9	8.9	GO:0003156	regulation of organ formation(GO:0003156)
8.9	8.9	GO:0015817	histidine transport(GO:0015817)
8.9	8.9	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
8.8	17.7	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
8.8	70.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
8.8	61.5	GO:0006516	glycoprotein catabolic process(GO:0006516)
8.8	17.6	GO:0009445	putrescine metabolic process(GO:0009445)
8.8	61.3	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
8.8	122.6	GO:0046329	negative regulation of JNK cascade(GO:0046329)
8.8	26.3	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
8.7	8.7	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
8.7	61.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
8.7	96.0	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
8.7	8.7	GO:0002432	granuloma formation(GO:0002432)
8.7	17.4	GO:1903779	regulation of cardiac conduction(GO:1903779)
8.7	8.7	GO:0006536	glutamate metabolic process(GO:0006536)
8.7	26.0	GO:0035269	protein O-linked mannosylation(GO:0035269)
8.7	86.6	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
8.7	43.3	GO:0031643	positive regulation of myelination(GO:0031643)
8.6	17.3	GO:0051683	establishment of Golgi localization(GO:0051683)
8.6	8.6	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
8.6	60.5	GO:0010039	response to iron ion(GO:0010039)
8.6	17.3	GO:0045821	positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
8.6	77.6	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
8.6	51.7	GO:0045072	regulation of interferon-gamma biosynthetic process(GO:0045072)
8.6	17.2	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
8.6	8.6	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
8.6	180.6	GO:0032456	endocytic recycling(GO:0032456)
8.6	25.7	GO:0030421	defecation(GO:0030421)
8.6	34.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
8.6	25.7	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
8.6	8.6	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
8.6	25.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
8.5	93.9	GO:0009299	mRNA transcription(GO:0009299)
8.5	76.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
8.5	25.6	GO:0002551	mast cell chemotaxis(GO:0002551)
8.5	42.6	GO:0000154	rRNA modification(GO:0000154)
8.5	8.5	GO:0046487	glyoxylate metabolic process(GO:0046487)
8.5	17.0	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
8.5	76.4	GO:0014044	Schwann cell development(GO:0014044)
8.5	33.9	GO:0051799	negative regulation of hair follicle development(GO:0051799)
8.5	67.7	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
8.5	42.3	GO:0050915	sensory perception of sour taste(GO:0050915)
8.5	50.7	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
8.4	16.9	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
8.4	25.3	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
8.4	50.6	GO:0060294	cilium movement involved in cell motility(GO:0060294)
8.4	33.7	GO:0006348	chromatin silencing at telomere(GO:0006348)
8.4	16.8	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
8.4	25.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
8.4	16.8	GO:0006971	hypotonic response(GO:0006971) cellular hypotonic response(GO:0071476)
8.4	8.4	GO:0048478	replication fork protection(GO:0048478)
8.4	42.0	GO:0015074	DNA integration(GO:0015074)
8.4	50.3	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
8.3	33.4	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
8.3	25.0	GO:0060023	soft palate development(GO:0060023)
8.3	16.7	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
8.3	33.2	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
8.3	224.1	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
8.3	41.4	GO:0019934	cGMP-mediated signaling(GO:0019934)
8.3	124.1	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
8.3	16.5	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
8.3	24.8	GO:1905208	negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
8.3	41.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
8.3	57.8	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
8.2	16.5	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
8.2	123.5	GO:0006353	DNA-templated transcription, termination(GO:0006353)
8.2	16.5	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
8.2	41.1	GO:0046415	urate metabolic process(GO:0046415)
8.2	8.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
8.2	8.2	GO:1902548	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
8.2	24.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
8.2	24.5	GO:1903427	negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
8.2	16.3	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
8.2	8.2	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
8.2	203.8	GO:1902850	mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
8.1	56.8	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
8.1	8.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
8.1	8.1	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
8.1	8.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
8.1	40.4	GO:0032096	negative regulation of response to food(GO:0032096)
8.1	24.2	GO:0045060	negative thymic T cell selection(GO:0045060)
8.1	56.5	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
8.1	88.8	GO:0034508	centromere complex assembly(GO:0034508)
8.0	16.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
8.0	16.1	GO:0006532	aspartate biosynthetic process(GO:0006532)
8.0	8.0	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
8.0	8.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
8.0	40.1	GO:0002098	tRNA wobble uridine modification(GO:0002098)
8.0	64.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
8.0	8.0	GO:0006942	regulation of striated muscle contraction(GO:0006942)
8.0	16.0	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
8.0	8.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
8.0	159.6	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
8.0	15.9	GO:0009070	serine family amino acid biosynthetic process(GO:0009070)
8.0	15.9	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
8.0	23.9	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
8.0	39.8	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
8.0	47.7	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
7.9	7.9	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
7.9	7.9	GO:0006983	ER overload response(GO:0006983)
7.9	23.8	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
7.9	23.8	GO:0071545	inositol phosphate catabolic process(GO:0071545)
7.9	245.5	GO:0043966	histone H3 acetylation(GO:0043966)
7.9	7.9	GO:0070189	kynurenine metabolic process(GO:0070189)
7.9	39.5	GO:0015871	choline transport(GO:0015871)
7.9	23.7	GO:0008295	spermidine biosynthetic process(GO:0008295)
7.9	47.4	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
7.9	39.4	GO:0009249	protein lipoylation(GO:0009249)
7.8	23.5	GO:0052547	regulation of peptidase activity(GO:0052547)
7.8	7.8	GO:0001828	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
7.8	23.5	GO:2000272	negative regulation of receptor activity(GO:2000272)
7.8	7.8	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
7.8	54.3	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
7.7	7.7	GO:0060623	regulation of chromosome condensation(GO:0060623)
7.7	15.5	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
7.7	15.4	GO:0060081	membrane hyperpolarization(GO:0060081)
7.7	7.7	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
7.7	15.4	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
7.7	15.4	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
7.7	7.7	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
7.7	23.0	GO:0090042	tubulin deacetylation(GO:0090042)
7.7	15.4	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
7.7	260.6	GO:0006446	regulation of translational initiation(GO:0006446)
7.6	22.8	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
7.6	91.0	GO:0030168	platelet activation(GO:0030168)
7.6	7.6	GO:0016095	polyprenol catabolic process(GO:0016095)
7.6	15.1	GO:0009247	glycolipid biosynthetic process(GO:0009247)
7.6	22.7	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of RIG-I signaling pathway(GO:0039536)
7.6	15.1	GO:0051307	meiotic chromosome separation(GO:0051307)
7.6	7.6	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
7.5	150.9	GO:0000266	mitochondrial fission(GO:0000266)
7.5	15.1	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
7.5	37.6	GO:0042448	progesterone metabolic process(GO:0042448)
7.5	15.0	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
7.5	97.5	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
7.5	22.5	GO:0098535	de novo centriole assembly(GO:0098535)
7.5	15.0	GO:0060613	fat pad development(GO:0060613)
7.5	52.4	GO:1904851	regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
7.5	7.5	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
7.5	22.4	GO:0006287	base-excision repair, gap-filling(GO:0006287)
7.5	52.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
7.5	7.5	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
7.5	37.3	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
7.5	44.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
7.5	52.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
7.4	14.9	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
7.4	59.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
7.4	7.4	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
7.4	52.0	GO:0043248	proteasome assembly(GO:0043248)
7.4	44.5	GO:0007080	mitotic metaphase plate congression(GO:0007080)
7.4	7.4	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
7.4	14.8	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
7.4	7.4	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.4	44.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
7.4	14.8	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
7.4	7.4	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
7.3	7.3	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
7.3	14.7	GO:0060018	astrocyte fate commitment(GO:0060018)
7.3	7.3	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
7.3	14.7	GO:0006304	DNA modification(GO:0006304)
7.3	73.3	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
7.3	14.6	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
7.3	29.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
7.3	21.9	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
7.3	21.9	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
7.3	21.9	GO:0034058	endosomal vesicle fusion(GO:0034058)
7.3	29.1	GO:0030321	transepithelial chloride transport(GO:0030321)
7.3	72.7	GO:0001659	temperature homeostasis(GO:0001659)
7.3	79.9	GO:0007035	vacuolar acidification(GO:0007035)
7.3	29.1	GO:0006776	vitamin A metabolic process(GO:0006776)
7.3	7.3	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
7.3	29.0	GO:0016925	protein sumoylation(GO:0016925)
7.2	21.7	GO:0022417	protein maturation by protein folding(GO:0022417)
7.2	57.8	GO:1902806	regulation of cell cycle G1/S phase transition(GO:1902806)
7.2	86.6	GO:0061436	establishment of skin barrier(GO:0061436)
7.2	7.2	GO:0046060	dATP metabolic process(GO:0046060)
7.2	72.1	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
7.2	21.6	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
7.2	43.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
7.2	43.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
7.2	416.0	GO:0006633	fatty acid biosynthetic process(GO:0006633)
7.2	7.2	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
7.2	186.3	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
7.2	200.5	GO:0045454	cell redox homeostasis(GO:0045454)
7.2	35.8	GO:0060484	lung-associated mesenchyme development(GO:0060484)
7.1	71.5	GO:0002115	store-operated calcium entry(GO:0002115)
7.1	28.6	GO:0071569	protein ufmylation(GO:0071569)
7.1	7.1	GO:0060631	regulation of meiosis I(GO:0060631)
7.1	42.7	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
7.1	255.1	GO:0008654	phospholipid biosynthetic process(GO:0008654)
7.1	14.1	GO:0021540	corpus callosum morphogenesis(GO:0021540)
7.1	77.7	GO:0060972	left/right pattern formation(GO:0060972)
7.1	49.4	GO:0030261	chromosome condensation(GO:0030261)
7.1	21.2	GO:0006013	mannose metabolic process(GO:0006013)
7.0	21.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
7.0	49.3	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
7.0	63.3	GO:0031648	protein destabilization(GO:0031648)
7.0	49.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
7.0	14.0	GO:0046849	bone remodeling(GO:0046849)
7.0	35.1	GO:0045577	regulation of B cell differentiation(GO:0045577)
7.0	21.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
7.0	7.0	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
7.0	146.6	GO:0009225	nucleotide-sugar metabolic process(GO:0009225)
7.0	27.9	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
7.0	62.6	GO:0072528	pyrimidine-containing compound biosynthetic process(GO:0072528)
6.9	34.7	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
6.9	6.9	GO:0001556	oocyte maturation(GO:0001556)
6.9	13.9	GO:0070314	G1 to G0 transition(GO:0070314)
6.9	13.8	GO:0072205	metanephric collecting duct development(GO:0072205)
6.9	82.9	GO:0006493	protein O-linked glycosylation(GO:0006493)
6.9	6.9	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
6.9	27.5	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
6.9	171.8	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
6.9	48.1	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
6.9	6.9	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
6.8	6.8	GO:0030818	negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
6.8	109.5	GO:0006308	DNA catabolic process(GO:0006308)
6.8	102.6	GO:0065002	intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
6.8	34.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
6.8	20.5	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
6.8	20.4	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
6.8	34.0	GO:0006477	protein sulfation(GO:0006477)
6.8	34.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
6.8	20.4	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
6.8	176.6	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
6.8	27.1	GO:0006116	NADH oxidation(GO:0006116)
6.8	47.4	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
6.8	13.5	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
6.8	6.8	GO:0061470	T follicular helper cell differentiation(GO:0061470)
6.8	6.8	GO:0016574	histone ubiquitination(GO:0016574)
6.7	20.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
6.7	256.1	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
6.7	13.5	GO:1903578	regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
6.7	6.7	GO:0072329	monocarboxylic acid catabolic process(GO:0072329)
6.7	26.9	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
6.7	20.2	GO:0007256	activation of JNKK activity(GO:0007256)
6.7	20.2	GO:0015697	quaternary ammonium group transport(GO:0015697)
6.7	13.4	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
6.7	26.8	GO:0006020	inositol metabolic process(GO:0006020)
6.7	6.7	GO:0071218	cellular response to misfolded protein(GO:0071218)
6.7	26.8	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
6.7	20.0	GO:0010459	negative regulation of heart rate(GO:0010459)
6.7	40.1	GO:0070875	positive regulation of glycogen metabolic process(GO:0070875)
6.7	6.7	GO:0045901	positive regulation of translational elongation(GO:0045901)
6.7	60.1	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
6.7	20.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
6.7	33.3	GO:0030033	microvillus assembly(GO:0030033)
6.6	13.3	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.6	46.4	GO:0042574	retinal metabolic process(GO:0042574)
6.6	13.2	GO:0033182	regulation of histone ubiquitination(GO:0033182)
6.6	13.2	GO:0034033	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
6.6	52.5	GO:0051450	myoblast proliferation(GO:0051450)
6.6	13.1	GO:0097484	dendrite extension(GO:0097484)
6.5	26.1	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
6.5	71.8	GO:0003351	epithelial cilium movement(GO:0003351)
6.5	430.7	GO:0050691	regulation of defense response to virus by host(GO:0050691)
6.5	39.1	GO:0046549	retinal cone cell development(GO:0046549)
6.5	19.5	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
6.5	52.0	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
6.5	19.5	GO:0043984	histone H4-K16 acetylation(GO:0043984)
6.5	6.5	GO:0018377	protein myristoylation(GO:0018377)
6.5	25.8	GO:2000108	positive regulation of leukocyte apoptotic process(GO:2000108)
6.5	38.7	GO:0014041	regulation of neuron maturation(GO:0014041)
6.4	19.3	GO:0035562	negative regulation of chromatin binding(GO:0035562)
6.4	25.8	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958)
6.4	6.4	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
6.4	32.1	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
6.4	6.4	GO:2000105	positive regulation of DNA-dependent DNA replication(GO:2000105)
6.4	102.5	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
6.4	25.6	GO:0061036	positive regulation of cartilage development(GO:0061036)
6.4	12.8	GO:0001826	inner cell mass cell differentiation(GO:0001826)
6.4	6.4	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
6.4	12.8	GO:0015884	folic acid transport(GO:0015884)
6.4	25.5	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
6.4	19.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
6.4	25.5	GO:0006167	AMP biosynthetic process(GO:0006167)
6.4	31.9	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
6.4	57.4	GO:0009595	detection of biotic stimulus(GO:0009595)
6.4	6.4	GO:0033046	negative regulation of sister chromatid segregation(GO:0033046)
6.4	19.1	GO:0046039	GTP metabolic process(GO:0046039)
6.4	6.4	GO:0043038	amino acid activation(GO:0043038)
6.4	38.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
6.3	6.3	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
6.3	6.3	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
6.3	25.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
6.3	12.6	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
6.3	31.6	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
6.3	44.2	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
6.3	176.5	GO:0002181	cytoplasmic translation(GO:0002181)
6.3	12.6	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
6.3	12.6	GO:0044778	meiotic cell cycle checkpoint(GO:0033313) meiotic DNA integrity checkpoint(GO:0044778)
6.3	31.5	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
6.3	18.9	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
6.3	6.3	GO:0032210	regulation of telomere maintenance via telomerase(GO:0032210)
6.3	6.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
6.3	50.3	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
6.3	12.6	GO:0051305	meiotic chromosome movement towards spindle pole(GO:0016344) meiotic cytokinesis(GO:0033206) chromosome movement towards spindle pole(GO:0051305)
6.3	12.5	GO:0001880	Mullerian duct regression(GO:0001880)
6.2	99.9	GO:0017144	drug metabolic process(GO:0017144)
6.2	12.5	GO:0036297	interstrand cross-link repair(GO:0036297)
6.2	49.8	GO:0030500	regulation of bone mineralization(GO:0030500)
6.2	49.5	GO:0051289	protein homotetramerization(GO:0051289)
6.2	24.7	GO:0010165	response to X-ray(GO:0010165)
6.2	74.2	GO:0090630	activation of GTPase activity(GO:0090630)
6.2	6.2	GO:0033131	regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
6.2	12.3	GO:0043654	recognition of apoptotic cell(GO:0043654)
6.2	104.9	GO:0051168	nuclear export(GO:0051168)
6.2	67.8	GO:1902749	regulation of cell cycle G2/M phase transition(GO:1902749)
6.2	24.7	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
6.1	12.3	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
6.1	12.3	GO:0018065	protein-cofactor linkage(GO:0018065)
6.1	6.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
6.1	12.2	GO:0048771	tissue remodeling(GO:0048771)
6.1	18.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
6.1	18.3	GO:0071684	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
6.1	6.1	GO:0007028	cytoplasm organization(GO:0007028)
6.1	6.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
6.1	12.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
6.1	12.1	GO:0009063	cellular amino acid catabolic process(GO:0009063)
6.1	6.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
6.1	24.2	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
6.1	12.1	GO:0032530	regulation of microvillus organization(GO:0032530)
6.1	6.1	GO:0009451	RNA modification(GO:0009451)
6.0	127.0	GO:0045494	photoreceptor cell maintenance(GO:0045494)
6.0	30.2	GO:0045141	meiotic telomere clustering(GO:0045141)
6.0	350.1	GO:0016579	protein deubiquitination(GO:0016579)
6.0	6.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
6.0	6.0	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
6.0	36.2	GO:0046326	positive regulation of glucose import(GO:0046326)
6.0	18.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
6.0	522.9	GO:0006310	DNA recombination(GO:0006310)
6.0	120.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
6.0	6.0	GO:0006534	cysteine metabolic process(GO:0006534) homocysteine metabolic process(GO:0050667)
6.0	12.0	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
6.0	29.9	GO:0042149	cellular response to glucose starvation(GO:0042149)
6.0	18.0	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
6.0	17.9	GO:0035810	positive regulation of urine volume(GO:0035810)
6.0	6.0	GO:0070828	heterochromatin organization(GO:0070828)
6.0	6.0	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
6.0	11.9	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
6.0	6.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
6.0	11.9	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
5.9	5.9	GO:0007599	hemostasis(GO:0007599)
5.9	11.9	GO:0097062	dendritic spine maintenance(GO:0097062)
5.9	17.8	GO:0071407	cellular response to organic cyclic compound(GO:0071407)
5.9	47.4	GO:0042572	retinol metabolic process(GO:0042572)
5.9	5.9	GO:0048148	behavioral response to cocaine(GO:0048148)
5.9	47.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
5.9	11.8	GO:0035610	protein side chain deglutamylation(GO:0035610)
5.9	11.8	GO:0072643	interferon-gamma secretion(GO:0072643)
5.9	5.9	GO:0009953	dorsal/ventral pattern formation(GO:0009953)
5.9	17.6	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
5.8	5.8	GO:0031268	pseudopodium organization(GO:0031268)
5.8	58.2	GO:0002021	response to dietary excess(GO:0002021)
5.8	5.8	GO:0060591	chondroblast differentiation(GO:0060591)
5.8	11.6	GO:0055088	lipid homeostasis(GO:0055088)
5.8	17.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
5.8	11.5	GO:0016556	mRNA modification(GO:0016556)
5.8	5.8	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
5.8	11.5	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
5.7	5.7	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
5.7	22.9	GO:0045144	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
5.7	5.7	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
5.7	79.8	GO:0044839	cell cycle G2/M phase transition(GO:0044839)
5.7	56.9	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
5.7	11.4	GO:0032482	Rab protein signal transduction(GO:0032482)
5.7	11.4	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
5.7	158.6	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
5.7	11.3	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
5.6	11.3	GO:0032352	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
5.6	16.9	GO:0040019	positive regulation of embryonic development(GO:0040019)
5.6	11.3	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
5.6	124.1	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
5.6	16.9	GO:0046599	regulation of centriole replication(GO:0046599)
5.6	95.8	GO:0046850	regulation of bone remodeling(GO:0046850)
5.6	5.6	GO:0007343	egg activation(GO:0007343)
5.6	28.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
5.6	106.6	GO:0007052	mitotic spindle organization(GO:0007052)
5.6	55.9	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
5.6	66.9	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
5.6	16.7	GO:0045351	type I interferon biosynthetic process(GO:0045351)
5.6	16.7	GO:0007000	nucleolus organization(GO:0007000)
5.6	105.6	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
5.6	11.1	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
5.6	33.3	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
5.5	44.4	GO:0015693	magnesium ion transport(GO:0015693)
5.5	22.1	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
5.5	5.5	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
5.5	5.5	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
5.5	5.5	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
5.5	11.0	GO:2000773	negative regulation of cellular senescence(GO:2000773)
5.5	11.0	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
5.5	16.5	GO:0060405	regulation of penile erection(GO:0060405)
5.5	33.0	GO:0034453	microtubule anchoring(GO:0034453)
5.5	5.5	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
5.5	16.4	GO:0033273	response to vitamin(GO:0033273)
5.5	27.4	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
5.5	27.4	GO:0061462	protein localization to lysosome(GO:0061462)
5.4	27.2	GO:0016125	sterol metabolic process(GO:0016125)
5.4	114.1	GO:0032092	positive regulation of protein binding(GO:0032092)
5.4	16.3	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
5.4	21.7	GO:0006040	amino sugar metabolic process(GO:0006040)
5.4	10.8	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
5.4	5.4	GO:0042503	tyrosine phosphorylation of Stat3 protein(GO:0042503)
5.4	5.4	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
5.4	16.2	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
5.4	5.4	GO:0003162	atrioventricular node development(GO:0003162)
5.4	26.9	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
5.4	102.2	GO:0051028	mRNA transport(GO:0051028)
5.4	16.1	GO:0060142	regulation of syncytium formation by plasma membrane fusion(GO:0060142)
5.4	21.5	GO:1990542	mitochondrial transmembrane transport(GO:1990542)
5.4	42.9	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
5.4	53.6	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
5.3	42.6	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
5.3	16.0	GO:0050994	regulation of lipid catabolic process(GO:0050994)
5.3	90.3	GO:0030042	actin filament depolymerization(GO:0030042)
5.3	15.9	GO:0061450	trophoblast cell migration(GO:0061450)
5.3	5.3	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
5.3	105.9	GO:0006829	zinc II ion transport(GO:0006829)
5.3	15.9	GO:0002159	desmosome assembly(GO:0002159)
5.3	5.3	GO:0032026	response to magnesium ion(GO:0032026)
5.3	15.8	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
5.3	10.6	GO:0009826	unidimensional cell growth(GO:0009826)
5.3	10.6	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
5.3	5.3	GO:0006450	regulation of translational fidelity(GO:0006450)
5.2	26.2	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
5.2	10.5	GO:0043490	malate-aspartate shuttle(GO:0043490)
5.2	162.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)
5.2	57.6	GO:0016180	snRNA processing(GO:0016180)
5.2	5.2	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
5.2	31.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
5.2	125.4	GO:0045576	mast cell activation(GO:0045576)
5.2	10.4	GO:0060068	vagina development(GO:0060068)
5.2	26.1	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
5.2	15.6	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
5.2	5.2	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
5.2	20.8	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
5.2	20.8	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
5.2	31.1	GO:0015809	arginine transport(GO:0015809)
5.2	31.1	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
5.2	72.6	GO:0015804	neutral amino acid transport(GO:0015804)
5.2	5.2	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
5.2	5.2	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
5.2	77.6	GO:0050873	brown fat cell differentiation(GO:0050873)
5.2	15.5	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
5.2	20.7	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
5.2	10.3	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
5.2	5.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
5.2	5.2	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
5.2	5.2	GO:0055119	relaxation of cardiac muscle(GO:0055119)
5.1	113.1	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
5.1	5.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
5.1	25.7	GO:0034063	stress granule assembly(GO:0034063)
5.1	10.3	GO:0090071	regulation of ribosome biogenesis(GO:0090069) negative regulation of ribosome biogenesis(GO:0090071)
5.1	20.5	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
5.1	10.3	GO:0002200	somatic diversification of immune receptors(GO:0002200)
5.1	41.0	GO:0019915	lipid storage(GO:0019915)
5.1	61.3	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
5.1	5.1	GO:0042045	epithelial fluid transport(GO:0042045)
5.1	5.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
5.1	5.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
5.1	40.6	GO:1903861	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
5.1	10.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
5.1	10.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
5.1	15.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
5.0	5.0	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
5.0	75.4	GO:0000075	cell cycle checkpoint(GO:0000075)
5.0	5.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
5.0	15.1	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
5.0	40.2	GO:0044804	nucleophagy(GO:0044804)
5.0	5.0	GO:0033603	positive regulation of dopamine secretion(GO:0033603) positive regulation of catecholamine secretion(GO:0033605)
5.0	10.0	GO:0051029	rRNA transport(GO:0051029)
5.0	20.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
5.0	5.0	GO:1900015	regulation of cytokine production involved in inflammatory response(GO:1900015)
5.0	24.8	GO:0006694	steroid biosynthetic process(GO:0006694)
5.0	5.0	GO:0019674	NAD metabolic process(GO:0019674)
5.0	59.5	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
5.0	29.7	GO:0031398	positive regulation of protein ubiquitination(GO:0031398)
4.9	19.8	GO:0035855	megakaryocyte development(GO:0035855)
4.9	39.6	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
4.9	9.9	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
4.9	14.8	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
4.9	19.8	GO:0033233	regulation of protein sumoylation(GO:0033233)
4.9	19.7	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
4.9	4.9	GO:0045346	MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346)
4.9	4.9	GO:0000963	mitochondrial RNA processing(GO:0000963)
4.9	9.8	GO:0010755	regulation of plasminogen activation(GO:0010755)
4.9	49.1	GO:0000186	activation of MAPKK activity(GO:0000186)
4.9	9.8	GO:1902031	regulation of NADP metabolic process(GO:1902031)
4.9	29.4	GO:0032060	bleb assembly(GO:0032060)
4.9	245.0	GO:0051607	defense response to virus(GO:0051607)
4.9	9.8	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
4.9	4.9	GO:0002830	positive regulation of type 2 immune response(GO:0002830)
4.9	53.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
4.9	4.9	GO:0034502	protein localization to chromosome(GO:0034502)
4.9	999.2	GO:0008380	RNA splicing(GO:0008380)
4.9	4.9	GO:0090110	cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
4.9	209.4	GO:1903749	positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
4.9	403.0	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
4.8	9.7	GO:0033762	response to glucagon(GO:0033762)
4.8	67.7	GO:0009206	ATP biosynthetic process(GO:0006754) purine nucleoside triphosphate biosynthetic process(GO:0009145) ribonucleoside triphosphate biosynthetic process(GO:0009201) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
4.8	9.7	GO:0031639	plasminogen activation(GO:0031639)
4.8	14.5	GO:0006641	triglyceride metabolic process(GO:0006641)
4.8	19.3	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
4.8	120.6	GO:0006261	DNA-dependent DNA replication(GO:0006261)
4.8	19.3	GO:0032204	regulation of telomere maintenance(GO:0032204)
4.8	4.8	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
4.8	14.5	GO:0070265	necrotic cell death(GO:0070265)
4.8	9.6	GO:0038066	p38MAPK cascade(GO:0038066)
4.8	4.8	GO:0002097	tRNA wobble base modification(GO:0002097)
4.8	4.8	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
4.8	4.8	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
4.8	9.6	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
4.8	14.4	GO:0042732	D-xylose metabolic process(GO:0042732)
4.8	52.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
4.8	19.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
4.8	9.6	GO:0030242	pexophagy(GO:0030242)
4.8	33.4	GO:0008209	androgen metabolic process(GO:0008209)
4.8	47.7	GO:0010508	positive regulation of autophagy(GO:0010508)
4.8	9.5	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
4.8	19.0	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
4.7	4.7	GO:0006102	isocitrate metabolic process(GO:0006102)
4.7	147.0	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
4.7	33.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
4.7	23.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
4.7	9.4	GO:0019079	viral genome replication(GO:0019079)
4.7	37.7	GO:0045116	protein neddylation(GO:0045116)
4.7	33.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
4.7	33.0	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
4.7	14.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
4.7	4.7	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
4.7	9.4	GO:0034421	post-translational protein acetylation(GO:0034421)
4.7	98.6	GO:0031333	negative regulation of protein complex assembly(GO:0031333)
4.7	51.6	GO:0060674	placenta blood vessel development(GO:0060674)
4.7	9.4	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
4.7	126.5	GO:0051297	centrosome organization(GO:0051297)
4.7	18.7	GO:0061085	regulation of histone H3-K27 methylation(GO:0061085)
4.7	46.8	GO:0072676	lymphocyte migration(GO:0072676)
4.7	18.7	GO:0006650	glycerophospholipid metabolic process(GO:0006650)
4.7	4.7	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
4.7	4.7	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
4.6	152.9	GO:0010942	positive regulation of cell death(GO:0010942)
4.6	9.3	GO:0010587	miRNA catabolic process(GO:0010587)
4.6	9.2	GO:0007020	microtubule nucleation(GO:0007020)
4.6	4.6	GO:0045622	regulation of T-helper cell differentiation(GO:0045622)
4.6	18.4	GO:0061029	eyelid development in camera-type eye(GO:0061029)
4.6	9.2	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
4.6	41.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
4.6	9.1	GO:0097264	self proteolysis(GO:0097264)
4.6	13.7	GO:0032897	negative regulation of viral transcription(GO:0032897)
4.5	4.5	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
4.5	9.1	GO:0071397	cellular response to cholesterol(GO:0071397)
4.5	4.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
4.5	9.1	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
4.5	18.1	GO:0030225	macrophage differentiation(GO:0030225)
4.5	9.1	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
4.5	9.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
4.5	9.0	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
4.5	85.6	GO:0035966	response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966)
4.5	18.0	GO:0008211	glucocorticoid metabolic process(GO:0008211)
4.5	4.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
4.5	40.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
4.5	13.4	GO:0042573	retinoic acid metabolic process(GO:0042573)
4.5	13.4	GO:0033136	serine phosphorylation of STAT3 protein(GO:0033136)
4.4	4.4	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
4.4	8.9	GO:0007144	female meiosis I(GO:0007144)
4.4	8.9	GO:0006903	vesicle targeting(GO:0006903)
4.4	26.6	GO:0030539	male genitalia development(GO:0030539)
4.4	13.3	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
4.4	22.1	GO:0001773	myeloid dendritic cell activation(GO:0001773)
4.4	66.3	GO:0030218	erythrocyte differentiation(GO:0030218)
4.4	8.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
4.4	4.4	GO:0043985	histone H4-R3 methylation(GO:0043985)
4.4	4.4	GO:0030322	stabilization of membrane potential(GO:0030322)
4.4	4.4	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
4.4	30.7	GO:0051973	positive regulation of telomerase activity(GO:0051973)
4.4	30.7	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
4.4	192.3	GO:0008033	tRNA processing(GO:0008033)
4.4	8.7	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
4.3	8.7	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
4.3	21.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
4.3	8.7	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.3	8.7	GO:0016322	neuron remodeling(GO:0016322)
4.3	21.6	GO:0006835	dicarboxylic acid transport(GO:0006835)
4.3	43.0	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
4.3	266.4	GO:0016072	rRNA metabolic process(GO:0016072)
4.3	4.3	GO:0061154	endothelial tube morphogenesis(GO:0061154)
4.3	4.3	GO:0070243	regulation of thymocyte apoptotic process(GO:0070243)
4.3	111.0	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
4.3	29.8	GO:0060412	ventricular septum morphogenesis(GO:0060412)
4.2	25.5	GO:0040014	regulation of multicellular organism growth(GO:0040014)
4.2	8.5	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
4.2	29.7	GO:0017156	calcium ion regulated exocytosis(GO:0017156)
4.2	8.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
4.2	25.4	GO:0010390	histone monoubiquitination(GO:0010390)
4.2	21.1	GO:0030224	monocyte differentiation(GO:0030224)
4.2	21.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
4.2	4.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
4.2	12.6	GO:0060768	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
4.2	58.7	GO:0007569	cell aging(GO:0007569)
4.2	50.2	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
4.2	16.6	GO:0098840	protein transport along microtubule(GO:0098840)
4.2	419.9	GO:0032259	methylation(GO:0032259)
4.2	8.3	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
4.2	74.7	GO:0060976	coronary vasculature development(GO:0060976)
4.1	16.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
4.1	4.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
4.1	4.1	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
4.1	16.6	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
4.1	4.1	GO:0050777	negative regulation of immune response(GO:0050777)
4.1	24.8	GO:0032781	positive regulation of ATPase activity(GO:0032781)
4.1	16.5	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
4.1	20.5	GO:0048535	lymph node development(GO:0048535)
4.1	4.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
4.1	8.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
4.1	8.2	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
4.1	4.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
4.1	24.6	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
4.1	4.1	GO:0040009	regulation of growth rate(GO:0040009)
4.1	4.1	GO:0010259	multicellular organism aging(GO:0010259)
4.1	4.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
4.1	8.1	GO:0070305	response to cGMP(GO:0070305)
4.1	85.2	GO:0009988	cell-cell recognition(GO:0009988)
4.1	16.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
4.0	16.2	GO:0016572	histone phosphorylation(GO:0016572)
4.0	4.0	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
4.0	8.1	GO:0048311	mitochondrion distribution(GO:0048311)
4.0	84.5	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
4.0	32.2	GO:0042991	transcription factor import into nucleus(GO:0042991)
4.0	60.3	GO:0016575	histone deacetylation(GO:0016575)
4.0	12.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
4.0	16.0	GO:0043030	regulation of macrophage activation(GO:0043030)
4.0	4.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
4.0	15.9	GO:0043276	anoikis(GO:0043276)
4.0	43.8	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
4.0	4.0	GO:0097039	protein linear polyubiquitination(GO:0097039)
3.9	3.9	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
3.9	7.9	GO:0046909	intermembrane transport(GO:0046909)
3.9	7.8	GO:0003356	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
3.9	78.3	GO:0002323	natural killer cell activation involved in immune response(GO:0002323)
3.9	7.8	GO:0070162	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.9	23.4	GO:0006289	nucleotide-excision repair(GO:0006289)
3.9	7.8	GO:0042832	defense response to protozoan(GO:0042832)
3.9	27.2	GO:0000338	protein deneddylation(GO:0000338)
3.9	7.8	GO:0010829	negative regulation of glucose transport(GO:0010829)
3.9	7.7	GO:0007252	I-kappaB phosphorylation(GO:0007252)
3.9	27.1	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
3.9	30.9	GO:0043297	apical junction assembly(GO:0043297)
3.9	81.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
3.9	15.4	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
3.8	3.8	GO:0043482	endosome to melanosome transport(GO:0035646) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
3.8	11.5	GO:0006071	glycerol metabolic process(GO:0006071)
3.8	69.0	GO:0050982	detection of mechanical stimulus(GO:0050982)
3.8	49.7	GO:0008333	endosome to lysosome transport(GO:0008333)
3.8	38.3	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
3.8	7.6	GO:0042092	type 2 immune response(GO:0042092)
3.8	7.6	GO:0051341	regulation of oxidoreductase activity(GO:0051341)
3.8	22.9	GO:0008053	mitochondrial fusion(GO:0008053)
3.8	11.4	GO:0060618	nipple development(GO:0060618)
3.8	15.2	GO:0001553	luteinization(GO:0001553)
3.8	41.9	GO:0008286	insulin receptor signaling pathway(GO:0008286)
3.8	15.2	GO:1904385	cellular response to angiotensin(GO:1904385) response to angiotensin(GO:1990776)
3.8	3.8	GO:1903887	motile primary cilium assembly(GO:1903887)
3.8	15.2	GO:0005980	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
3.8	3.8	GO:0021764	amygdala development(GO:0021764)
3.8	71.7	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
3.8	165.8	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
3.8	7.5	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
3.7	3.7	GO:0014002	astrocyte development(GO:0014002)
3.7	11.2	GO:0016540	protein autoprocessing(GO:0016540)
3.7	7.5	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
3.7	22.4	GO:0014904	myotube cell development(GO:0014904)
3.7	52.1	GO:0006821	chloride transport(GO:0006821)
3.7	3.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
3.7	36.6	GO:0019933	cAMP-mediated signaling(GO:0019933)
3.7	11.0	GO:0097320	membrane tubulation(GO:0097320)
3.6	7.3	GO:0045738	negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
3.6	3.6	GO:0070417	cellular response to cold(GO:0070417)
3.6	10.9	GO:0030325	adrenal gland development(GO:0030325)
3.6	21.8	GO:0035988	chondrocyte proliferation(GO:0035988)
3.6	14.5	GO:0007492	endoderm development(GO:0007492)
3.6	7.2	GO:0061157	mRNA destabilization(GO:0061157)
3.6	3.6	GO:0016064	immunoglobulin mediated immune response(GO:0016064)
3.6	195.2	GO:0006396	RNA processing(GO:0006396)
3.6	3.6	GO:0009584	detection of visible light(GO:0009584)
3.6	39.7	GO:0045727	positive regulation of translation(GO:0045727)
3.6	39.5	GO:0034505	tooth mineralization(GO:0034505)
3.6	7.2	GO:0048599	oocyte development(GO:0048599)
3.6	3.6	GO:0060416	response to growth hormone(GO:0060416)
3.6	7.2	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661)
3.6	3.6	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
3.6	14.2	GO:0051602	response to electrical stimulus(GO:0051602)
3.5	28.3	GO:0030816	positive regulation of cAMP metabolic process(GO:0030816)
3.5	10.6	GO:0048659	smooth muscle cell proliferation(GO:0048659)
3.5	7.1	GO:0071773	response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
3.5	10.6	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
3.5	3.5	GO:0015698	inorganic anion transport(GO:0015698)
3.5	28.2	GO:0048144	fibroblast proliferation(GO:0048144)
3.5	10.5	GO:0045760	positive regulation of action potential(GO:0045760)
3.5	28.0	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
3.5	14.0	GO:0045453	bone resorption(GO:0045453)
3.5	62.9	GO:0007585	respiratory gaseous exchange(GO:0007585)
3.5	7.0	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
3.5	10.4	GO:0010470	regulation of gastrulation(GO:0010470)
3.5	27.8	GO:0001706	endoderm formation(GO:0001706)
3.5	27.8	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
3.5	3.5	GO:0046070	dGTP metabolic process(GO:0046070)
3.5	162.3	GO:0045444	fat cell differentiation(GO:0045444)
3.4	3.4	GO:0051591	response to cAMP(GO:0051591)
3.4	44.6	GO:0051865	protein autoubiquitination(GO:0051865)
3.4	3.4	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
3.4	82.4	GO:0006958	complement activation, classical pathway(GO:0006958)
3.4	13.7	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
3.4	13.7	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
3.4	27.2	GO:0007368	determination of left/right symmetry(GO:0007368)
3.4	10.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
3.4	13.6	GO:1901660	calcium ion export(GO:1901660)
3.4	6.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
3.4	16.9	GO:0000002	mitochondrial genome maintenance(GO:0000002)
3.4	30.3	GO:0050853	B cell receptor signaling pathway(GO:0050853)
3.4	134.7	GO:0006281	DNA repair(GO:0006281)
3.4	10.1	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.4	6.7	GO:0034976	response to endoplasmic reticulum stress(GO:0034976)
3.4	3.4	GO:0002092	positive regulation of receptor internalization(GO:0002092)
3.3	16.7	GO:0042537	benzene-containing compound metabolic process(GO:0042537)
3.3	3.3	GO:0030431	sleep(GO:0030431)
3.3	16.7	GO:0050884	neuromuscular process controlling posture(GO:0050884)
3.3	23.4	GO:1990403	embryonic brain development(GO:1990403)
3.3	16.7	GO:0019363	pyridine nucleotide biosynthetic process(GO:0019363)
3.3	3.3	GO:0006213	pyrimidine nucleoside metabolic process(GO:0006213)
3.3	3.3	GO:0070384	Harderian gland development(GO:0070384)
3.3	3.3	GO:0042312	regulation of vasodilation(GO:0042312)
3.3	72.7	GO:0009408	response to heat(GO:0009408)
3.3	78.9	GO:0032543	mitochondrial translation(GO:0032543)
3.3	36.1	GO:0009411	response to UV(GO:0009411)
3.3	9.8	GO:1903232	melanosome assembly(GO:1903232)
3.3	3.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
3.3	6.5	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
3.3	3.3	GO:0046185	aldehyde catabolic process(GO:0046185)
3.3	29.3	GO:0016525	negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
3.3	19.5	GO:0070670	response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
3.2	6.5	GO:0048255	mRNA stabilization(GO:0048255)
3.2	355.9	GO:0051603	proteolysis involved in cellular protein catabolic process(GO:0051603)
3.2	54.9	GO:0009060	aerobic respiration(GO:0009060)
3.2	9.7	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
3.2	12.9	GO:0007032	endosome organization(GO:0007032)
3.2	35.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
3.2	38.6	GO:0043627	response to estrogen(GO:0043627)
3.2	3.2	GO:1990001	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
3.2	3.2	GO:0050755	chemokine metabolic process(GO:0050755)
3.2	54.1	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
3.2	9.5	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
3.2	6.4	GO:0018210	peptidyl-threonine modification(GO:0018210)
3.2	9.5	GO:0060005	vestibular reflex(GO:0060005)
3.2	3.2	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028)
3.1	9.4	GO:0044458	motile cilium assembly(GO:0044458)
3.1	6.3	GO:0070831	basement membrane assembly(GO:0070831)
3.1	6.2	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
3.1	28.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
3.1	9.3	GO:0097435	fibril organization(GO:0097435)
3.1	34.2	GO:0044243	multicellular organism catabolic process(GO:0044243)
3.1	6.2	GO:0016188	synaptic vesicle maturation(GO:0016188)
3.1	3.1	GO:0006553	lysine metabolic process(GO:0006553)
3.1	6.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
3.1	48.9	GO:0034728	nucleosome organization(GO:0034728)
3.1	3.1	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
3.0	3.0	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
3.0	12.1	GO:0015893	drug transport(GO:0015893)
3.0	9.1	GO:0048485	sympathetic nervous system development(GO:0048485)
3.0	9.0	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
3.0	12.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
3.0	48.2	GO:0007030	Golgi organization(GO:0007030)
3.0	21.1	GO:0016926	protein desumoylation(GO:0016926)
3.0	3.0	GO:0070813	hydrogen sulfide metabolic process(GO:0070813)
3.0	12.0	GO:0036159	inner dynein arm assembly(GO:0036159)
3.0	6.0	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
3.0	6.0	GO:0006399	tRNA metabolic process(GO:0006399)
3.0	116.3	GO:0043547	positive regulation of GTPase activity(GO:0043547)
3.0	3.0	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
3.0	11.9	GO:0006638	neutral lipid metabolic process(GO:0006638)
3.0	14.8	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
3.0	3.0	GO:0033687	osteoblast proliferation(GO:0033687)
3.0	3.0	GO:0043383	negative T cell selection(GO:0043383)
2.9	2.9	GO:0032098	regulation of appetite(GO:0032098)
2.9	2.9	GO:0097286	iron ion import(GO:0097286)
2.9	79.2	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
2.9	14.6	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
2.9	104.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
2.9	180.4	GO:0042060	wound healing(GO:0042060)
2.9	37.7	GO:0006749	glutathione metabolic process(GO:0006749)
2.9	8.7	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
2.9	210.4	GO:0006470	protein dephosphorylation(GO:0006470)
2.9	5.7	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
2.9	2.9	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
2.9	8.6	GO:0051642	centrosome localization(GO:0051642)
2.8	2.8	GO:0046148	pigment biosynthetic process(GO:0046148)
2.8	14.2	GO:0043968	histone H2A acetylation(GO:0043968)
2.8	2.8	GO:0042637	catagen(GO:0042637)
2.8	14.2	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
2.8	14.2	GO:0032620	interleukin-17 production(GO:0032620)
2.8	11.3	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
2.8	2.8	GO:0071672	negative regulation of smooth muscle cell chemotaxis(GO:0071672)
2.8	11.2	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
2.8	8.4	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
2.8	106.2	GO:0042254	ribosome biogenesis(GO:0042254)
2.8	2.8	GO:2000171	negative regulation of dendrite development(GO:2000171)
2.8	8.4	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
2.8	30.6	GO:0043550	regulation of lipid kinase activity(GO:0043550)
2.8	8.3	GO:1901068	guanosine-containing compound metabolic process(GO:1901068)
2.8	5.5	GO:0060536	cartilage morphogenesis(GO:0060536)
2.8	5.5	GO:0006414	translational elongation(GO:0006414)
2.8	2.8	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
2.8	5.5	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
2.8	2.8	GO:0006591	ornithine metabolic process(GO:0006591)
2.8	5.5	GO:0003170	heart valve development(GO:0003170)
2.7	129.0	GO:0006457	protein folding(GO:0006457)
2.7	2.7	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
2.7	2.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
2.7	81.0	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
2.7	32.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
2.7	5.4	GO:0048251	elastic fiber assembly(GO:0048251)
2.7	2.7	GO:0015695	organic cation transport(GO:0015695)
2.7	79.7	GO:0019439	aromatic compound catabolic process(GO:0019439)
2.6	60.9	GO:0007519	skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
2.6	329.4	GO:0006412	translation(GO:0006412)
2.6	2.6	GO:0042402	cellular biogenic amine catabolic process(GO:0042402)
2.6	5.2	GO:0036514	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
2.6	15.6	GO:0045824	negative regulation of innate immune response(GO:0045824)
2.6	2.6	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
2.6	13.0	GO:0046548	retinal rod cell development(GO:0046548)
2.6	5.2	GO:0006527	arginine catabolic process(GO:0006527)
2.6	13.0	GO:0018344	protein geranylgeranylation(GO:0018344)
2.6	2.6	GO:0006543	glutamine catabolic process(GO:0006543)
2.6	5.2	GO:0002690	positive regulation of leukocyte chemotaxis(GO:0002690)
2.6	7.8	GO:0048266	behavioral response to pain(GO:0048266)
2.6	20.7	GO:0008272	sulfate transport(GO:0008272)
2.6	69.7	GO:0006006	glucose metabolic process(GO:0006006)
2.6	25.8	GO:0060325	face morphogenesis(GO:0060325)
2.6	10.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
2.6	5.1	GO:2000194	regulation of female gonad development(GO:2000194)
2.6	112.4	GO:0070647	protein modification by small protein conjugation or removal(GO:0070647)
2.5	5.1	GO:1903960	negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
2.5	7.6	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
2.5	35.5	GO:0006953	acute-phase response(GO:0006953)
2.5	32.8	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
2.5	7.5	GO:0009649	entrainment of circadian clock(GO:0009649)
2.5	5.0	GO:0042628	mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
2.5	2.5	GO:0035092	sperm chromatin condensation(GO:0035092)
2.5	52.4	GO:0042493	response to drug(GO:0042493)
2.5	2.5	GO:1903998	regulation of eating behavior(GO:1903998)
2.5	2.5	GO:0060235	lens induction in camera-type eye(GO:0060235)
2.5	2.5	GO:0046834	lipid phosphorylation(GO:0046834)
2.5	4.9	GO:2000035	regulation of stem cell division(GO:2000035)
2.5	2.5	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
2.5	2.5	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
2.5	4.9	GO:0071467	cellular response to pH(GO:0071467)
2.5	2.5	GO:0006817	phosphate ion transport(GO:0006817)
2.4	4.9	GO:0018200	peptidyl-glutamic acid modification(GO:0018200)
2.4	2.4	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
2.4	2.4	GO:0045778	positive regulation of ossification(GO:0045778)
2.4	12.2	GO:0006825	copper ion transport(GO:0006825)
2.4	2.4	GO:0051385	response to mineralocorticoid(GO:0051385)
2.4	4.8	GO:0042891	antibiotic transport(GO:0042891)
2.4	4.8	GO:0051657	maintenance of organelle location(GO:0051657)
2.4	2.4	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.4	7.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
2.4	4.8	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
2.4	4.8	GO:0000060	protein import into nucleus, translocation(GO:0000060)
2.4	9.5	GO:0050435	beta-amyloid metabolic process(GO:0050435)
2.4	576.6	GO:0055114	oxidation-reduction process(GO:0055114)
2.4	2.4	GO:0002637	regulation of immunoglobulin production(GO:0002637)
2.4	9.4	GO:0009235	cobalamin metabolic process(GO:0009235)
2.4	14.1	GO:0031279	regulation of cyclase activity(GO:0031279)
2.4	11.8	GO:0061756	leukocyte adhesion to vascular endothelial cell(GO:0061756)
2.3	2.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
2.3	25.7	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
2.3	9.3	GO:0043029	T cell homeostasis(GO:0043029)
2.3	4.7	GO:0030262	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
2.3	9.2	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
2.3	20.7	GO:0070229	negative regulation of lymphocyte apoptotic process(GO:0070229)
2.3	16.1	GO:1902017	regulation of cilium assembly(GO:1902017)
2.3	18.4	GO:0043524	negative regulation of neuron apoptotic process(GO:0043524)
2.3	9.2	GO:0001967	suckling behavior(GO:0001967)
2.3	11.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
2.3	2.3	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.3	4.6	GO:0002121	inter-male aggressive behavior(GO:0002121)
2.3	4.5	GO:2000378	negative regulation of reactive oxygen species metabolic process(GO:2000378)
2.3	4.5	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
2.3	4.5	GO:0090273	regulation of somatostatin secretion(GO:0090273)
2.3	2.3	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
2.3	2.3	GO:2001242	regulation of intrinsic apoptotic signaling pathway(GO:2001242)
2.2	2.2	GO:0046958	nonassociative learning(GO:0046958)
2.2	2.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
2.2	2.2	GO:0007412	axon target recognition(GO:0007412)
2.2	51.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
2.2	2.2	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
2.2	11.1	GO:0007127	meiosis I(GO:0007127)
2.2	2.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
2.2	2.2	GO:0043620	regulation of DNA-templated transcription in response to stress(GO:0043620)
2.2	6.7	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
2.2	2.2	GO:0070633	transepithelial transport(GO:0070633)
2.2	2.2	GO:0048525	negative regulation of viral process(GO:0048525)
2.2	15.4	GO:0061512	protein localization to cilium(GO:0061512)
2.2	2.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
2.2	2.2	GO:0050798	activated T cell proliferation(GO:0050798)
2.2	17.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
2.2	8.6	GO:0042177	negative regulation of protein catabolic process(GO:0042177)
2.1	6.4	GO:0032868	response to insulin(GO:0032868)
2.1	6.4	GO:0010812	negative regulation of cell-substrate adhesion(GO:0010812)
2.1	8.5	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
2.1	6.3	GO:0021984	adenohypophysis development(GO:0021984)
2.1	4.2	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
2.1	2.1	GO:0030252	growth hormone secretion(GO:0030252)
2.1	4.2	GO:0006265	DNA topological change(GO:0006265)
2.1	2.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
2.1	4.2	GO:0060259	regulation of feeding behavior(GO:0060259)
2.1	37.4	GO:0007059	chromosome segregation(GO:0007059)
2.1	2.1	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.1	4.1	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
2.1	180.7	GO:0051346	negative regulation of hydrolase activity(GO:0051346)
2.1	326.5	GO:0048232	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
2.1	112.9	GO:0060271	cilium morphogenesis(GO:0060271)
2.1	18.5	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.0	2.0	GO:0034637	cellular carbohydrate biosynthetic process(GO:0034637)
2.0	18.3	GO:0045103	intermediate filament-based process(GO:0045103)
2.0	10.1	GO:0009615	response to virus(GO:0009615)
2.0	2.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
2.0	6.0	GO:0048733	sebaceous gland development(GO:0048733)
2.0	12.1	GO:0042278	purine nucleoside metabolic process(GO:0042278)
2.0	4.0	GO:0032350	regulation of hormone metabolic process(GO:0032350)
2.0	2.0	GO:0010155	regulation of proton transport(GO:0010155)
2.0	2.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
2.0	9.9	GO:0006884	cell volume homeostasis(GO:0006884)
2.0	2.0	GO:0050906	detection of stimulus involved in sensory perception(GO:0050906)
2.0	5.9	GO:0006465	signal peptide processing(GO:0006465)
2.0	13.8	GO:0007631	feeding behavior(GO:0007631)
2.0	15.7	GO:0014850	response to muscle activity(GO:0014850)
2.0	3.9	GO:0050892	intestinal absorption(GO:0050892)
2.0	3.9	GO:0009404	toxin metabolic process(GO:0009404)
1.9	3.9	GO:0097480	synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
1.9	19.5	GO:0007034	vacuolar transport(GO:0007034)
1.9	1.9	GO:0060856	establishment of blood-brain barrier(GO:0060856)
1.9	1.9	GO:0001951	intestinal D-glucose absorption(GO:0001951)
1.9	3.8	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.9	3.8	GO:0097284	hepatocyte apoptotic process(GO:0097284)
1.9	11.3	GO:0035458	cellular response to interferon-beta(GO:0035458)
1.9	3.7	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
1.9	1.9	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
1.9	1.9	GO:0045924	regulation of female receptivity(GO:0045924)
1.8	1.8	GO:0032411	positive regulation of transporter activity(GO:0032411)
1.8	49.5	GO:0071241	cellular response to inorganic substance(GO:0071241)
1.8	1.8	GO:0001923	B-1 B cell differentiation(GO:0001923)
1.8	1.8	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.8	1.8	GO:0002931	response to ischemia(GO:0002931)
1.8	1.8	GO:0090313	regulation of protein targeting to membrane(GO:0090313)
1.8	1.8	GO:0045932	negative regulation of muscle contraction(GO:0045932)
1.8	5.3	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
1.8	3.5	GO:0044843	cell cycle G1/S phase transition(GO:0044843)
1.8	5.3	GO:0032465	regulation of cytokinesis(GO:0032465)
1.7	73.2	GO:0016042	lipid catabolic process(GO:0016042)
1.7	5.2	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
1.7	1.7	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
1.7	43.0	GO:0006906	vesicle fusion(GO:0006906)
1.7	6.8	GO:0031638	zymogen activation(GO:0031638)
1.7	1.7	GO:0045933	positive regulation of muscle contraction(GO:0045933)
1.7	80.7	GO:0006816	calcium ion transport(GO:0006816)
1.7	31.9	GO:0031424	keratinization(GO:0031424)
1.7	1.7	GO:0001895	retina homeostasis(GO:0001895)
1.7	1.7	GO:0032370	positive regulation of lipid transport(GO:0032370)
1.7	15.0	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
1.7	1.7	GO:0035561	regulation of chromatin binding(GO:0035561)
1.7	3.3	GO:0060711	labyrinthine layer development(GO:0060711)
1.6	1.6	GO:0022613	ribonucleoprotein complex biogenesis(GO:0022613)
1.6	4.9	GO:0050701	interleukin-1 secretion(GO:0050701) interleukin-1 beta secretion(GO:0050702)
1.6	6.5	GO:0050852	T cell receptor signaling pathway(GO:0050852)
1.6	1.6	GO:0035878	nail development(GO:0035878)
1.6	1.6	GO:0022617	extracellular matrix disassembly(GO:0022617)
1.6	21.1	GO:0006974	cellular response to DNA damage stimulus(GO:0006974)
1.6	8.1	GO:0042159	protein depalmitoylation(GO:0002084) lipoprotein catabolic process(GO:0042159) macromolecule depalmitoylation(GO:0098734)
1.6	1.6	GO:0046324	regulation of glucose import(GO:0046324)
1.6	1.6	GO:2000021	regulation of ion homeostasis(GO:2000021)
1.6	1.6	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
1.6	3.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
1.6	3.2	GO:0051014	actin filament severing(GO:0051014)
1.6	7.9	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
1.6	4.7	GO:0050832	defense response to fungus(GO:0050832)
1.6	1.6	GO:0048102	autophagic cell death(GO:0048102)
1.6	73.6	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
1.5	12.2	GO:0016050	vesicle organization(GO:0016050)
1.5	21.3	GO:0048545	response to steroid hormone(GO:0048545)
1.5	14.9	GO:0019835	cytolysis(GO:0019835)
1.5	1.5	GO:0015670	carbon dioxide transport(GO:0015670)
1.5	1.5	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
1.5	7.3	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
1.5	20.4	GO:0006873	cellular ion homeostasis(GO:0006873)
1.5	4.4	GO:0042135	neurotransmitter catabolic process(GO:0042135)
1.4	1.4	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.4	5.8	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
1.4	35.9	GO:0072507	divalent inorganic cation homeostasis(GO:0072507)
1.4	10.0	GO:0009607	response to biotic stimulus(GO:0009607)
1.4	1.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.4	1.4	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
1.4	7.1	GO:0050821	protein stabilization(GO:0050821)
1.4	1.4	GO:0044117	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117)
1.4	92.7	GO:0042742	defense response to bacterium(GO:0042742)
1.4	2.8	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
1.4	1.4	GO:0001573	ganglioside metabolic process(GO:0001573)
1.4	2.8	GO:0045931	positive regulation of mitotic cell cycle(GO:0045931)
1.4	1.4	GO:0055070	copper ion homeostasis(GO:0055070)
1.4	4.1	GO:0031581	hemidesmosome assembly(GO:0031581)
1.3	2.7	GO:0043043	peptide biosynthetic process(GO:0043043)
1.3	2.7	GO:0042481	regulation of odontogenesis(GO:0042481)
1.3	4.0	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
1.3	1.3	GO:0060017	parathyroid gland development(GO:0060017)
1.3	132.6	GO:0019236	response to pheromone(GO:0019236)
1.3	2.5	GO:0045110	intermediate filament bundle assembly(GO:0045110)
1.3	6.3	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
1.2	3.7	GO:0042157	lipoprotein metabolic process(GO:0042157)
1.2	7.4	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
1.2	7.4	GO:1901264	carbohydrate derivative transport(GO:1901264)
1.2	3.7	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
1.2	1.2	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.2	1.2	GO:0005984	disaccharide metabolic process(GO:0005984)
1.2	1.2	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
1.2	1.2	GO:0051132	NK T cell activation(GO:0051132)
1.2	1289.7	GO:0007608	sensory perception of smell(GO:0007608)
1.2	1.2	GO:0002090	regulation of receptor internalization(GO:0002090)
1.1	5.7	GO:0030316	osteoclast differentiation(GO:0030316)
1.1	41.1	GO:0006954	inflammatory response(GO:0006954)
1.1	1.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
1.1	1.1	GO:0003161	cardiac conduction system development(GO:0003161)
1.1	2.3	GO:1904478	regulation of intestinal absorption(GO:1904478)
1.1	1.1	GO:2001020	regulation of response to DNA damage stimulus(GO:2001020)
1.1	1.1	GO:0035113	embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
1.1	6.7	GO:0031214	biomineral tissue development(GO:0031214)
1.1	3.3	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
1.1	1.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.1	1.1	GO:0050957	equilibrioception(GO:0050957)
1.1	48.4	GO:0007601	visual perception(GO:0007601)
1.1	1.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
1.1	1.1	GO:0070231	T cell apoptotic process(GO:0070231)
1.1	1.1	GO:0006171	cAMP biosynthetic process(GO:0006171)
1.1	2.1	GO:0044375	regulation of peroxisome size(GO:0044375)
1.0	1.0	GO:0002699	positive regulation of immune effector process(GO:0002699)
1.0	1.0	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
1.0	36.3	GO:0007605	sensory perception of sound(GO:0007605)
1.0	1.0	GO:0018094	protein polyglycylation(GO:0018094)
1.0	3.1	GO:0043409	negative regulation of MAPK cascade(GO:0043409)
1.0	24.4	GO:0043086	negative regulation of catalytic activity(GO:0043086)
1.0	6.9	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
1.0	2.0	GO:0031647	regulation of protein stability(GO:0031647)
1.0	3.9	GO:0033344	cholesterol efflux(GO:0033344)
1.0	2.9	GO:0010469	regulation of receptor activity(GO:0010469)
1.0	1.0	GO:0032635	interleukin-6 production(GO:0032635)
1.0	1.9	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.9	0.9	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.9	0.9	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.9	1.8	GO:0033059	cellular pigmentation(GO:0033059)
0.9	1.8	GO:0008089	anterograde axonal transport(GO:0008089)
0.9	0.9	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.9	1.8	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
0.9	0.9	GO:0042542	response to hydrogen peroxide(GO:0042542)
0.9	0.9	GO:0060525	prostate glandular acinus development(GO:0060525)
0.9	0.9	GO:0032094	response to food(GO:0032094)
0.9	0.9	GO:0002385	mucosal immune response(GO:0002385)
0.9	0.9	GO:0021782	glial cell development(GO:0021782)
0.9	0.9	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.8	1.7	GO:0002507	tolerance induction(GO:0002507)
0.8	3.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.8	28.9	GO:0006952	defense response(GO:0006952)
0.8	3.3	GO:0007224	smoothened signaling pathway(GO:0007224)
0.8	0.8	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.8	0.8	GO:1901655	cellular response to ketone(GO:1901655)
0.8	3.9	GO:0045930	negative regulation of mitotic cell cycle(GO:0045930)
0.8	0.8	GO:0046683	response to organophosphorus(GO:0046683)
0.8	10.1	GO:0006959	humoral immune response(GO:0006959)
0.8	1.6	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.8	7.7	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.8	1.5	GO:0001757	somite specification(GO:0001757)
0.8	1.5	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.7	2.2	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.7	0.7	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.7	2.2	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.7	0.7	GO:0019321	pentose metabolic process(GO:0019321)
0.7	10.0	GO:0010629	negative regulation of gene expression(GO:0010629)
0.7	0.7	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.7	0.7	GO:0014015	positive regulation of gliogenesis(GO:0014015)
0.7	36.9	GO:0032496	response to lipopolysaccharide(GO:0032496)
0.7	0.7	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.7	658.3	GO:0097659	nucleic acid-templated transcription(GO:0097659)
0.7	0.7	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.7	0.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.7	0.7	GO:2000737	negative regulation of stem cell differentiation(GO:2000737)
0.6	1.9	GO:0072337	modified amino acid transport(GO:0072337)
0.6	34.4	GO:0006897	endocytosis(GO:0006897)
0.6	0.6	GO:0014827	phasic smooth muscle contraction(GO:0014821) intestine smooth muscle contraction(GO:0014827)
0.6	0.6	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.6	0.6	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.6	3.0	GO:0044782	cilium organization(GO:0044782)
0.6	0.6	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
0.6	2.3	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.6	13.9	GO:0008643	carbohydrate transport(GO:0008643)
0.6	0.6	GO:0006091	generation of precursor metabolites and energy(GO:0006091)
0.6	0.6	GO:0042417	dopamine metabolic process(GO:0042417)
0.6	1.1	GO:1903115	regulation of actin filament-based movement(GO:1903115)
0.6	3.3	GO:0051180	vitamin transport(GO:0051180)
0.5	8.5	GO:0070482	response to oxygen levels(GO:0070482)
0.5	1.0	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.5	105.7	GO:0006508	proteolysis(GO:0006508)
0.5	42.0	GO:0005975	carbohydrate metabolic process(GO:0005975)
0.5	0.5	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.5	0.5	GO:0021511	spinal cord patterning(GO:0021511)
0.5	0.5	GO:0007616	long-term memory(GO:0007616)
0.4	4.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.4	61.4	GO:0055085	transmembrane transport(GO:0055085)
0.4	0.4	GO:0085029	extracellular matrix assembly(GO:0085029)
0.3	0.3	GO:0001919	regulation of receptor recycling(GO:0001919)
0.3	0.3	GO:0040029	regulation of gene expression, epigenetic(GO:0040029)
0.3	0.3	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.3	0.3	GO:0060443	mammary gland morphogenesis(GO:0060443)
0.3	3.9	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.3	0.3	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.3	0.3	GO:0008355	olfactory learning(GO:0008355)
0.2	0.2	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.2	0.2	GO:0032528	microvillus organization(GO:0032528)
0.2	0.2	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.2	0.4	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2	0.2	GO:0006576	cellular biogenic amine metabolic process(GO:0006576)
0.1	0.3	GO:0006768	biotin metabolic process(GO:0006768)
0.1	6.9	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
0.1	0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.1	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.1	0.5	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.1	0.9	GO:0048017	inositol lipid-mediated signaling(GO:0048017)
0.1	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0072520	seminiferous tubule development(GO:0072520)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
101.1	505.6	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
92.9	557.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
81.1	81.1	GO:0032587	ruffle membrane(GO:0032587)
71.3	213.8	GO:0046691	intracellular canaliculus(GO:0046691)
56.9	170.7	GO:0005833	hemoglobin complex(GO:0005833)
54.9	219.5	GO:1990130	Iml1 complex(GO:1990130)
45.9	275.5	GO:0000138	Golgi trans cisterna(GO:0000138)
40.4	121.3	GO:0097451	glial limiting end-foot(GO:0097451)
37.6	225.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
37.0	111.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
36.5	109.6	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
35.8	71.7	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
32.4	97.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
31.9	63.9	GO:0032127	dense core granule membrane(GO:0032127)
31.5	126.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
31.5	157.4	GO:0033093	Weibel-Palade body(GO:0033093)
29.7	89.2	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
29.7	118.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
29.5	177.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
29.4	235.5	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
28.7	287.4	GO:0097539	ciliary transition fiber(GO:0097539)
28.7	200.9	GO:0008290	F-actin capping protein complex(GO:0008290)
28.7	315.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
28.2	423.5	GO:0000421	autophagosome membrane(GO:0000421)
28.0	251.7	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
26.5	132.7	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
25.1	75.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
25.0	275.0	GO:0031143	pseudopodium(GO:0031143)
24.4	195.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
24.2	120.9	GO:0005828	kinetochore microtubule(GO:0005828)
23.9	95.6	GO:0033269	internode region of axon(GO:0033269)
23.4	140.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
22.5	67.6	GO:0005745	m-AAA complex(GO:0005745)
22.4	112.1	GO:0044326	dendritic spine neck(GO:0044326)
22.4	291.1	GO:0036038	MKS complex(GO:0036038)
22.4	178.8	GO:0005677	chromatin silencing complex(GO:0005677)
22.3	201.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
22.1	88.5	GO:0070545	PeBoW complex(GO:0070545)
22.0	66.0	GO:0097413	Lewy body(GO:0097413)
21.7	173.4	GO:0043203	axon hillock(GO:0043203)
21.5	64.4	GO:0030125	clathrin vesicle coat(GO:0030125)
21.3	127.9	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
21.2	1529.5	GO:0030863	cortical cytoskeleton(GO:0030863)
21.1	506.5	GO:0097228	sperm principal piece(GO:0097228)
20.4	81.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
20.3	81.4	GO:0031094	platelet dense tubular network(GO:0031094)
19.8	871.4	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
19.7	434.1	GO:0090544	BAF-type complex(GO:0090544)
19.7	78.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
19.5	97.7	GO:0005663	DNA replication factor C complex(GO:0005663)
19.5	78.1	GO:0035339	SPOTS complex(GO:0035339)
19.4	58.1	GO:0000811	GINS complex(GO:0000811)
19.3	58.0	GO:0031298	replication fork protection complex(GO:0031298)
19.3	57.9	GO:0032585	multivesicular body membrane(GO:0032585)
19.2	38.5	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
19.2	172.9	GO:0043020	NADPH oxidase complex(GO:0043020)
19.0	57.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
18.8	18.8	GO:0097422	tubular endosome(GO:0097422)
18.7	168.0	GO:0090533	cation-transporting ATPase complex(GO:0090533)
18.6	464.3	GO:0008305	integrin complex(GO:0008305)
18.5	129.3	GO:0032591	dendritic spine membrane(GO:0032591)
18.2	91.2	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
18.2	401.0	GO:0031941	filamentous actin(GO:0031941)
18.1	54.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
18.1	54.3	GO:0036449	microtubule minus-end(GO:0036449)
17.9	89.5	GO:0044613	nuclear pore central transport channel(GO:0044613)
17.8	106.9	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
17.8	177.8	GO:0031080	nuclear pore outer ring(GO:0031080)
17.7	300.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
17.6	335.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
17.6	52.9	GO:0071437	invadopodium(GO:0071437)
17.5	17.5	GO:0005903	brush border(GO:0005903)
17.4	52.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
16.9	16.9	GO:0034709	methylosome(GO:0034709)
16.8	50.5	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
16.8	50.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
16.8	385.5	GO:0030131	clathrin adaptor complex(GO:0030131)
16.4	65.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
16.4	16.4	GO:1990423	RZZ complex(GO:1990423)
16.3	32.6	GO:0031088	platelet dense granule membrane(GO:0031088)
16.1	145.0	GO:0005869	dynactin complex(GO:0005869)
16.0	256.4	GO:0000145	exocyst(GO:0000145)
15.9	366.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
15.9	79.4	GO:0005827	polar microtubule(GO:0005827)
15.9	79.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
15.7	110.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
15.7	220.1	GO:0097440	apical dendrite(GO:0097440)
15.6	62.5	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
15.5	31.0	GO:0089701	U2AF(GO:0089701)
15.5	123.9	GO:0044666	MLL3/4 complex(GO:0044666)
15.4	138.8	GO:0031010	ISWI-type complex(GO:0031010)
15.2	15.2	GO:0031523	Myb complex(GO:0031523)
15.2	15.2	GO:0097149	centralspindlin complex(GO:0097149)
15.1	136.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
15.1	30.1	GO:0044316	cone cell pedicle(GO:0044316)
15.0	150.1	GO:0008278	cohesin complex(GO:0008278)
15.0	45.0	GO:0005588	collagen type V trimer(GO:0005588)
15.0	59.8	GO:0002079	inner acrosomal membrane(GO:0002079)
15.0	59.8	GO:0016602	CCAAT-binding factor complex(GO:0016602)
14.8	133.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
14.7	14.7	GO:0097450	astrocyte end-foot(GO:0097450)
14.6	102.0	GO:0000788	nuclear nucleosome(GO:0000788)
14.5	43.6	GO:0030915	Smc5-Smc6 complex(GO:0030915)
14.5	58.1	GO:0044530	supraspliceosomal complex(GO:0044530)
14.5	43.4	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
14.4	14.4	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
14.2	71.2	GO:0043198	dendritic shaft(GO:0043198)
14.2	28.5	GO:0070939	Dsl1p complex(GO:0070939)
14.2	42.5	GO:0005899	insulin receptor complex(GO:0005899)
14.1	28.2	GO:0097542	ciliary tip(GO:0097542)
14.0	98.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
14.0	42.0	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
13.8	800.3	GO:0005795	Golgi stack(GO:0005795)
13.7	54.7	GO:0071141	SMAD protein complex(GO:0071141)
13.6	40.8	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
13.6	40.8	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
13.6	40.7	GO:1990923	PET complex(GO:1990923)
13.6	230.6	GO:0001673	male germ cell nucleus(GO:0001673)
13.5	108.3	GO:0030314	junctional membrane complex(GO:0030314)
13.4	53.7	GO:0002142	stereocilia ankle link complex(GO:0002142)
13.4	67.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
13.4	174.5	GO:0034704	calcium channel complex(GO:0034704)
13.4	147.1	GO:0005652	nuclear lamina(GO:0005652)
13.3	53.3	GO:0097524	sperm plasma membrane(GO:0097524)
13.2	79.2	GO:0071986	Ragulator complex(GO:0071986)
13.1	92.0	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
13.1	52.4	GO:0071439	clathrin complex(GO:0071439)
13.1	39.3	GO:1990462	omegasome(GO:1990462)
13.0	52.0	GO:0043073	germ cell nucleus(GO:0043073)
13.0	91.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
12.9	90.6	GO:0031931	TORC1 complex(GO:0031931)
12.8	89.9	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
12.8	64.2	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
12.8	127.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
12.7	12.7	GO:0042827	platelet dense granule(GO:0042827)
12.7	50.9	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
12.7	76.1	GO:0031415	NatA complex(GO:0031415)
12.7	721.2	GO:0000118	histone deacetylase complex(GO:0000118)
12.6	529.7	GO:0017053	transcriptional repressor complex(GO:0017053)
12.5	311.5	GO:0005771	multivesicular body(GO:0005771)
12.3	98.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
12.2	440.3	GO:0005905	clathrin-coated pit(GO:0005905)
12.2	36.7	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
12.2	219.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
12.2	133.8	GO:0031528	microvillus membrane(GO:0031528)
12.1	398.3	GO:0016592	mediator complex(GO:0016592)
12.0	83.9	GO:0042382	paraspeckles(GO:0042382)
12.0	24.0	GO:0044327	dendritic spine head(GO:0044327)
11.9	23.9	GO:0031595	nuclear proteasome complex(GO:0031595)
11.9	143.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
11.9	107.4	GO:0002116	semaphorin receptor complex(GO:0002116)
11.9	35.6	GO:0005914	spot adherens junction(GO:0005914)
11.8	59.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
11.8	129.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
11.7	23.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
11.7	35.0	GO:0016939	kinesin II complex(GO:0016939)
11.7	81.7	GO:0008385	IkappaB kinase complex(GO:0008385)
11.6	93.0	GO:0008180	COP9 signalosome(GO:0008180)
11.6	34.7	GO:0044611	nuclear pore inner ring(GO:0044611)
11.6	57.8	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
11.6	138.7	GO:0042581	specific granule(GO:0042581)
11.5	276.2	GO:0055038	recycling endosome membrane(GO:0055038)
11.5	115.1	GO:0046581	intercellular canaliculus(GO:0046581)
11.5	11.5	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
11.5	22.9	GO:0032133	chromosome passenger complex(GO:0032133)
11.4	125.4	GO:0044292	dendrite terminus(GO:0044292)
11.4	11.4	GO:0097418	neurofibrillary tangle(GO:0097418)
11.4	34.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
11.3	260.4	GO:0005776	autophagosome(GO:0005776)
11.3	45.2	GO:1990909	Wnt signalosome(GO:1990909)
11.3	33.9	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
11.2	11.2	GO:0097208	alveolar lamellar body(GO:0097208)
11.2	22.4	GO:0032584	growth cone membrane(GO:0032584)
11.2	55.9	GO:0035859	Seh1-associated complex(GO:0035859)
11.2	100.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
11.2	11.2	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
11.1	33.4	GO:0019815	B cell receptor complex(GO:0019815)
11.1	475.8	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
11.0	11.0	GO:0045178	basal part of cell(GO:0045178)
11.0	131.9	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
11.0	131.9	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
11.0	109.9	GO:0042405	nuclear inclusion body(GO:0042405)
10.9	10.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
10.9	10.9	GO:0043219	lateral loop(GO:0043219)
10.9	76.1	GO:0033263	CORVET complex(GO:0033263)
10.8	32.5	GO:0001650	fibrillar center(GO:0001650)
10.8	216.2	GO:0005680	anaphase-promoting complex(GO:0005680)
10.8	172.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
10.7	10.7	GO:0030137	COPI-coated vesicle(GO:0030137)
10.7	21.4	GO:0005642	annulate lamellae(GO:0005642)
10.6	10.6	GO:0032444	activin responsive factor complex(GO:0032444)
10.6	42.4	GO:0001651	dense fibrillar component(GO:0001651)
10.6	180.0	GO:0000242	pericentriolar material(GO:0000242)
10.6	105.7	GO:0016235	aggresome(GO:0016235)
10.6	337.8	GO:0008023	transcription elongation factor complex(GO:0008023)
10.4	83.1	GO:0031091	platelet alpha granule(GO:0031091)
10.4	41.5	GO:0030127	COPII vesicle coat(GO:0030127)
10.4	72.5	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
10.3	20.7	GO:1990597	AIP1-IRE1 complex(GO:1990597)
10.3	41.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
10.3	113.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
10.3	185.2	GO:0030904	retromer complex(GO:0030904)
10.3	41.1	GO:0001917	photoreceptor inner segment(GO:0001917)
10.2	71.7	GO:0097431	mitotic spindle pole(GO:0097431)
10.2	10.2	GO:0033270	paranode region of axon(GO:0033270)
10.2	20.3	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
10.1	30.3	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
10.1	241.8	GO:0005689	U12-type spliceosomal complex(GO:0005689)
10.1	20.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
10.1	502.9	GO:0042641	actomyosin(GO:0042641)
10.0	421.2	GO:0016363	nuclear matrix(GO:0016363)
10.0	30.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
9.9	169.0	GO:0034451	centriolar satellite(GO:0034451)
9.9	128.4	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
9.8	39.3	GO:0097452	GAIT complex(GO:0097452)
9.8	88.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
9.8	540.0	GO:0016605	PML body(GO:0016605)
9.8	48.9	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
9.8	303.1	GO:0098791	Golgi subcompartment(GO:0098791)
9.7	58.3	GO:0030894	replisome(GO:0030894)
9.6	77.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
9.6	38.5	GO:0005927	muscle tendon junction(GO:0005927)
9.6	19.2	GO:0000791	euchromatin(GO:0000791)
9.6	9.6	GO:0070761	pre-snoRNP complex(GO:0070761)
9.6	641.5	GO:1990204	oxidoreductase complex(GO:1990204)
9.6	105.2	GO:0002102	podosome(GO:0002102)
9.5	56.8	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
9.4	28.3	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
9.4	75.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
9.4	28.1	GO:0044232	organelle membrane contact site(GO:0044232)
9.3	56.0	GO:0017119	Golgi transport complex(GO:0017119)
9.3	503.6	GO:0000502	proteasome complex(GO:0000502)
9.3	27.9	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
9.3	27.8	GO:0032279	asymmetric synapse(GO:0032279)
9.3	120.6	GO:0010369	chromocenter(GO:0010369)
9.3	27.8	GO:0031430	M band(GO:0031430)
9.3	333.3	GO:0005643	nuclear pore(GO:0005643)
9.2	92.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
9.2	82.9	GO:0000813	ESCRT I complex(GO:0000813)
9.1	200.7	GO:0001772	immunological synapse(GO:0001772)
9.1	27.4	GO:0042583	chromaffin granule(GO:0042583)
9.0	903.9	GO:0000775	chromosome, centromeric region(GO:0000775)
9.0	45.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
9.0	234.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
9.0	45.0	GO:0045098	type III intermediate filament(GO:0045098)
9.0	62.9	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
9.0	44.9	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
9.0	18.0	GO:0030870	Mre11 complex(GO:0030870)
9.0	71.7	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
9.0	26.9	GO:0000346	transcription export complex(GO:0000346)
8.9	26.8	GO:0005955	calcineurin complex(GO:0005955)
8.9	8.9	GO:0036488	CHOP-C/EBP complex(GO:0036488)
8.9	124.1	GO:0043205	fibril(GO:0043205)
8.8	70.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
8.8	79.5	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
8.8	35.1	GO:0000796	condensin complex(GO:0000796)
8.7	96.1	GO:0032039	integrator complex(GO:0032039)
8.7	8.7	GO:0042788	polysomal ribosome(GO:0042788)
8.7	26.0	GO:0097443	sorting endosome(GO:0097443)
8.6	102.7	GO:0005876	spindle microtubule(GO:0005876)
8.5	68.3	GO:0070652	HAUS complex(GO:0070652)
8.5	8.5	GO:0097470	ribbon synapse(GO:0097470)
8.5	25.5	GO:0070938	contractile ring(GO:0070938)
8.5	25.5	GO:0000805	X chromosome(GO:0000805)
8.5	50.9	GO:0034464	BBSome(GO:0034464)
8.5	110.1	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
8.5	25.4	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
8.5	2258.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
8.5	42.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
8.4	405.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
8.4	59.0	GO:0031090	organelle membrane(GO:0031090)
8.4	58.9	GO:0060091	kinocilium(GO:0060091)
8.4	16.8	GO:0097543	ciliary inversin compartment(GO:0097543)
8.4	16.8	GO:0001739	sex chromatin(GO:0001739)
8.3	191.9	GO:0055037	recycling endosome(GO:0055037)
8.3	83.2	GO:0031011	Ino80 complex(GO:0031011)
8.3	66.5	GO:0005697	telomerase holoenzyme complex(GO:0005697)
8.3	74.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
8.3	91.0	GO:0030914	STAGA complex(GO:0030914)
8.2	99.0	GO:0035869	ciliary transition zone(GO:0035869)
8.2	49.4	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
8.2	32.9	GO:0001891	phagocytic cup(GO:0001891)
8.2	1010.4	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
8.2	16.4	GO:0031594	neuromuscular junction(GO:0031594)
8.2	90.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
8.2	146.9	GO:0035145	exon-exon junction complex(GO:0035145)
8.1	16.2	GO:0097512	cardiac myofibril(GO:0097512)
8.1	24.2	GO:0000974	Prp19 complex(GO:0000974)
8.1	16.1	GO:0043218	compact myelin(GO:0043218)
8.0	176.5	GO:0016529	sarcoplasmic reticulum(GO:0016529)
8.0	16.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
8.0	88.0	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
8.0	16.0	GO:0044309	neuron spine(GO:0044309)
7.9	71.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
7.9	23.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
7.9	79.3	GO:0071004	U2-type prespliceosome(GO:0071004)
7.9	8618.4	GO:0005829	cytosol(GO:0005829)
7.9	182.0	GO:0012505	endomembrane system(GO:0012505)
7.8	15.7	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
7.8	195.2	GO:0031201	SNARE complex(GO:0031201)
7.8	62.2	GO:0033391	chromatoid body(GO:0033391)
7.7	15.5	GO:0005687	U4 snRNP(GO:0005687)
7.7	77.3	GO:0044815	DNA packaging complex(GO:0044815)
7.7	15.4	GO:0033268	node of Ranvier(GO:0033268)
7.7	15.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
7.6	7.6	GO:0005686	U2 snRNP(GO:0005686)
7.6	114.5	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
7.6	15.2	GO:0030056	hemidesmosome(GO:0030056)
7.6	30.5	GO:0031932	TORC2 complex(GO:0031932)
7.6	30.4	GO:1990745	EARP complex(GO:1990745)
7.6	22.8	GO:0000781	chromosome, telomeric region(GO:0000781)
7.6	30.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
7.5	52.5	GO:0000124	SAGA complex(GO:0000124)
7.5	67.4	GO:0002080	acrosomal membrane(GO:0002080)
7.5	7.5	GO:0071010	prespliceosome(GO:0071010)
7.4	22.3	GO:0005577	fibrinogen complex(GO:0005577)
7.4	14.8	GO:0071011	precatalytic spliceosome(GO:0071011)
7.4	296.2	GO:0000793	condensed chromosome(GO:0000793)
7.4	96.0	GO:0030014	CCR4-NOT complex(GO:0030014)
7.4	14.7	GO:0097255	R2TP complex(GO:0097255)
7.3	14.7	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
7.3	14.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
7.3	58.0	GO:0045335	phagocytic vesicle(GO:0045335)
7.2	14.5	GO:0051233	spindle midzone(GO:0051233)
7.2	144.3	GO:0031519	PcG protein complex(GO:0031519)
7.1	56.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
7.1	14.2	GO:0070469	respiratory chain(GO:0070469)
7.1	28.4	GO:0016600	flotillin complex(GO:0016600)
7.1	262.3	GO:0016459	myosin complex(GO:0016459)
7.1	77.8	GO:0035861	site of double-strand break(GO:0035861)
7.1	21.2	GO:0071001	U4/U6 snRNP(GO:0071001)
7.1	28.3	GO:0035631	CD40 receptor complex(GO:0035631)
7.0	337.4	GO:0044440	endosomal part(GO:0044440)
7.0	7.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
7.0	13.9	GO:0032389	MutLalpha complex(GO:0032389)
6.9	145.4	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
6.9	7399.9	GO:0005654	nucleoplasm(GO:0005654)
6.9	13.8	GO:0098536	deuterosome(GO:0098536)
6.9	20.7	GO:0031501	mannosyltransferase complex(GO:0031501)
6.9	178.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
6.9	479.8	GO:0072562	blood microparticle(GO:0072562)
6.8	40.9	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
6.8	40.8	GO:0030880	RNA polymerase complex(GO:0030880)
6.8	27.2	GO:0005796	Golgi lumen(GO:0005796)
6.7	13.5	GO:0044224	juxtaparanode region of axon(GO:0044224)
6.7	20.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
6.6	1574.6	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
6.6	39.5	GO:0031616	spindle pole centrosome(GO:0031616)
6.5	418.1	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
6.5	632.1	GO:0005759	mitochondrial matrix(GO:0005759)
6.5	103.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
6.5	45.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
6.4	530.6	GO:0000139	Golgi membrane(GO:0000139)
6.4	370.8	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
6.4	6.4	GO:0043209	myelin sheath(GO:0043209)
6.3	38.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
6.3	12.6	GO:0030689	Noc complex(GO:0030689)
6.3	200.2	GO:0019898	extrinsic component of membrane(GO:0019898)
6.2	3811.5	GO:0005739	mitochondrion(GO:0005739)
6.2	6.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
6.2	24.7	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
6.1	18.4	GO:0042627	chylomicron(GO:0042627)
6.0	281.7	GO:0008021	synaptic vesicle(GO:0008021)
5.9	113.0	GO:0005811	lipid particle(GO:0005811)
5.9	17.8	GO:0031417	NatC complex(GO:0031417)
5.9	29.4	GO:0045120	pronucleus(GO:0045120)
5.9	29.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
5.8	993.6	GO:0005768	endosome(GO:0005768)
5.8	115.1	GO:0030133	transport vesicle(GO:0030133)
5.6	73.0	GO:0030992	intraciliary transport particle B(GO:0030992)
5.6	55.8	GO:0043034	costamere(GO:0043034)
5.5	27.7	GO:0031512	motile primary cilium(GO:0031512)
5.5	11.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
5.5	569.3	GO:0031975	envelope(GO:0031975)
5.5	27.5	GO:0030057	desmosome(GO:0030057)
5.5	5.5	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603) INO80-type complex(GO:0097346)
5.5	32.8	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
5.5	16.4	GO:0005896	interleukin-6 receptor complex(GO:0005896)
5.5	480.5	GO:0016323	basolateral plasma membrane(GO:0016323)
5.5	158.2	GO:0016328	lateral plasma membrane(GO:0016328)
5.4	147.1	GO:0034707	chloride channel complex(GO:0034707)
5.4	140.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
5.4	475.7	GO:1990234	transferase complex(GO:1990234)
5.3	5.3	GO:0031258	lamellipodium membrane(GO:0031258)
5.3	10.5	GO:0001520	outer dense fiber(GO:0001520)
5.2	5.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
5.2	1491.6	GO:0005794	Golgi apparatus(GO:0005794)
5.1	81.8	GO:0005913	cell-cell adherens junction(GO:0005913)
5.1	71.3	GO:0044853	plasma membrane raft(GO:0044853)
5.1	15.3	GO:0042612	MHC class I protein complex(GO:0042612)
5.0	59.9	GO:0001750	photoreceptor outer segment(GO:0001750)
5.0	24.9	GO:0032426	stereocilium tip(GO:0032426)
4.9	819.6	GO:0098552	side of membrane(GO:0098552)
4.9	9.9	GO:0048476	Holliday junction resolvase complex(GO:0048476)
4.9	3058.4	GO:0005783	endoplasmic reticulum(GO:0005783)
4.9	111.7	GO:0042383	sarcolemma(GO:0042383)
4.8	92.0	GO:0005929	cilium(GO:0005929)
4.8	435.3	GO:0005667	transcription factor complex(GO:0005667)
4.8	4.8	GO:0005726	perichromatin fibrils(GO:0005726)
4.8	4.8	GO:0000439	core TFIIH complex(GO:0000439)
4.8	47.6	GO:0043234	protein complex(GO:0043234)
4.8	14.3	GO:0030688	preribosome, small subunit precursor(GO:0030688)
4.7	4.7	GO:0001652	granular component(GO:0001652)
4.6	55.6	GO:0005844	polysome(GO:0005844)
4.6	9.3	GO:0005840	ribosome(GO:0005840)
4.6	4.6	GO:0044299	C-fiber(GO:0044299)
4.6	41.3	GO:0015629	actin cytoskeleton(GO:0015629)
4.5	2531.7	GO:0031982	vesicle(GO:0031982)
4.5	107.6	GO:0000228	nuclear chromosome(GO:0000228)
4.5	53.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
4.5	476.9	GO:0005874	microtubule(GO:0005874)
4.3	4.3	GO:0016528	sarcoplasm(GO:0016528)
4.2	63.6	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
4.2	223.9	GO:0031225	anchored component of membrane(GO:0031225)
4.2	4.2	GO:0032155	cell division site(GO:0032153) cell division site part(GO:0032155)
4.1	4.1	GO:0005875	microtubule associated complex(GO:0005875)
4.1	53.2	GO:0000922	spindle pole(GO:0000922)
4.0	9430.4	GO:0005737	cytoplasm(GO:0005737)
4.0	32.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
3.9	3.9	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
3.7	3.7	GO:0032993	protein-DNA complex(GO:0032993)
3.7	7.4	GO:0097225	sperm midpiece(GO:0097225)
3.6	21.8	GO:0043204	perikaryon(GO:0043204)
3.6	3.6	GO:0044297	cell body(GO:0044297)
3.6	18.0	GO:0097223	sperm part(GO:0097223)
3.4	44.1	GO:0098793	presynapse(GO:0098793)
3.4	10.1	GO:0005684	U2-type spliceosomal complex(GO:0005684)
3.3	9.9	GO:0097526	spliceosomal tri-snRNP complex(GO:0097526)
3.3	6.5	GO:0042555	MCM complex(GO:0042555)
3.3	74.9	GO:0016324	apical plasma membrane(GO:0016324)
3.2	413.3	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
3.2	6.3	GO:1902494	catalytic complex(GO:1902494)
3.2	22.1	GO:1902555	endoribonuclease complex(GO:1902555)
3.1	40.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
3.1	65.0	GO:0005694	chromosome(GO:0005694)
3.0	3208.3	GO:0043231	intracellular membrane-bounded organelle(GO:0043231)
2.9	5.9	GO:0032420	stereocilium(GO:0032420)
2.9	327.3	GO:0009986	cell surface(GO:0009986)
2.9	2255.0	GO:0005576	extracellular region(GO:0005576)
2.8	39.8	GO:0005922	connexon complex(GO:0005922)
2.8	3025.6	GO:0005886	plasma membrane(GO:0005886)
2.6	4098.8	GO:0016020	membrane(GO:0016020)
2.4	259.8	GO:0005622	intracellular(GO:0005622)
1.8	9.2	GO:0097458	neuron part(GO:0097458)
1.8	25.2	GO:0005623	cell(GO:0005623)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
126.0	504.1	GO:0031720	haptoglobin binding(GO:0031720)
94.0	376.2	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
85.3	597.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
81.7	81.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
81.1	243.3	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
80.7	322.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
79.7	318.8	GO:0000293	ferric-chelate reductase activity(GO:0000293)
79.2	237.6	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
65.5	196.5	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
62.5	250.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
61.3	245.2	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
56.0	112.0	GO:0031721	hemoglobin alpha binding(GO:0031721)
55.7	389.7	GO:0019957	C-C chemokine binding(GO:0019957)
54.7	273.6	GO:0019960	C-X3-C chemokine binding(GO:0019960)
53.0	159.1	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
52.5	157.6	GO:0030350	iron-responsive element binding(GO:0030350)
50.8	152.3	GO:0004064	arylesterase activity(GO:0004064)
48.4	145.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
48.2	144.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
47.8	143.4	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
47.2	188.7	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
47.1	188.6	GO:0009374	biotin binding(GO:0009374)
43.0	258.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
42.7	128.2	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
42.0	839.2	GO:0030506	ankyrin binding(GO:0030506)
41.7	125.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
41.3	41.3	GO:0042910	xenobiotic transporter activity(GO:0042910)
40.7	81.3	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
40.6	324.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
40.2	160.8	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
39.3	274.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
38.6	154.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
38.4	38.4	GO:1990459	transferrin receptor binding(GO:1990459)
38.0	190.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
37.7	113.1	GO:0070644	vitamin D response element binding(GO:0070644)
37.2	334.9	GO:0015168	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
36.9	147.5	GO:0004127	cytidylate kinase activity(GO:0004127)
36.6	292.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
35.7	71.4	GO:1901612	cardiolipin binding(GO:1901612)
35.5	71.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
34.6	242.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
34.2	171.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
33.9	33.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
33.6	100.8	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
33.4	100.3	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
33.3	166.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
33.3	199.6	GO:0004311	farnesyltranstransferase activity(GO:0004311)
33.1	99.3	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
33.1	132.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
32.1	192.9	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
32.0	64.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
32.0	159.9	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
31.8	95.3	GO:0001069	regulatory region RNA binding(GO:0001069)
31.6	63.2	GO:0070412	R-SMAD binding(GO:0070412)
31.1	249.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
30.9	92.7	GO:0031711	bradykinin receptor binding(GO:0031711)
30.2	90.7	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
30.0	360.5	GO:0016208	AMP binding(GO:0016208)
29.8	89.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
29.6	177.7	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
28.9	231.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
28.6	28.6	GO:0004713	protein tyrosine kinase activity(GO:0004713)
28.5	56.9	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
28.2	84.7	GO:0019961	interferon binding(GO:0019961)
28.2	56.3	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
28.1	56.3	GO:0061676	importin-alpha family protein binding(GO:0061676)
27.5	109.9	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
27.3	354.8	GO:0070300	phosphatidic acid binding(GO:0070300)
27.1	108.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
26.8	134.2	GO:0005131	growth hormone receptor binding(GO:0005131)
26.8	214.5	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
26.4	26.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
26.2	78.5	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
26.2	340.1	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
26.1	78.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
25.7	51.3	GO:0051920	peroxiredoxin activity(GO:0051920)
25.2	176.2	GO:0016803	ether hydrolase activity(GO:0016803)
25.1	150.4	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
25.0	50.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
24.8	74.5	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
24.6	221.6	GO:0016004	phospholipase activator activity(GO:0016004)
24.6	836.7	GO:0016831	carboxy-lyase activity(GO:0016831)
24.2	24.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
24.2	72.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
24.2	145.0	GO:0045505	dynein intermediate chain binding(GO:0045505)
24.1	120.3	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
24.1	72.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
23.6	70.8	GO:2001070	starch binding(GO:2001070)
23.6	188.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
23.6	70.7	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
23.5	211.9	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
23.5	164.2	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
23.4	23.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
23.3	209.9	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
23.3	93.2	GO:0005047	signal recognition particle binding(GO:0005047)
23.3	93.0	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
23.2	208.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
22.9	45.8	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
22.9	205.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
22.8	68.5	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
22.6	67.7	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
22.3	111.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
22.1	88.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
22.0	44.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
22.0	66.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
22.0	65.9	GO:0051425	PTB domain binding(GO:0051425)
21.7	282.5	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
21.6	64.9	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
21.6	64.8	GO:0019887	protein kinase regulator activity(GO:0019887)
21.6	86.4	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
21.3	21.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
21.2	84.9	GO:0015375	glycine:sodium symporter activity(GO:0015375)
21.1	147.7	GO:0046790	virion binding(GO:0046790)
21.0	63.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
21.0	63.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
20.8	62.3	GO:0045134	uridine-diphosphatase activity(GO:0045134)
20.7	82.8	GO:0004849	uridine kinase activity(GO:0004849)
20.7	82.7	GO:0070051	fibrinogen binding(GO:0070051)
20.5	61.5	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
20.3	61.0	GO:0008422	beta-glucosidase activity(GO:0008422)
20.1	100.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
20.0	80.2	GO:0015057	thrombin receptor activity(GO:0015057)
20.0	99.9	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
19.9	79.7	GO:0004566	beta-glucuronidase activity(GO:0004566)
19.9	297.8	GO:0005521	lamin binding(GO:0005521)
19.8	39.7	GO:0004096	catalase activity(GO:0004096)
19.8	79.2	GO:0043559	insulin binding(GO:0043559)
19.8	39.6	GO:0016419	S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
19.5	78.2	GO:0005344	oxygen transporter activity(GO:0005344)
19.4	19.4	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
19.3	57.8	GO:0034186	apolipoprotein A-I binding(GO:0034186)
19.2	77.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
19.2	172.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
19.0	56.9	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
18.9	56.8	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
18.6	540.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
18.5	203.9	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
18.5	55.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
18.5	73.9	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
18.4	36.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
18.3	36.6	GO:0016842	amidine-lyase activity(GO:0016842)
18.2	54.5	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
18.1	72.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
17.9	322.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
17.9	53.6	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
17.9	428.5	GO:0045502	dynein binding(GO:0045502)
17.8	267.4	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
17.8	53.4	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
17.8	266.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
17.7	53.2	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
17.7	88.7	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
17.7	70.7	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
17.7	35.3	GO:0002060	purine nucleobase binding(GO:0002060)
17.6	176.0	GO:0019206	nucleoside kinase activity(GO:0019206)
17.6	87.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
17.6	70.2	GO:0050693	LBD domain binding(GO:0050693)
17.5	35.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
17.5	87.4	GO:0046624	sphingolipid transporter activity(GO:0046624)
17.4	364.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
17.3	414.3	GO:0030507	spectrin binding(GO:0030507)
17.2	137.8	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
17.1	68.5	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
17.1	51.3	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
17.1	51.2	GO:0004104	cholinesterase activity(GO:0004104)
17.0	119.3	GO:0018638	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
17.0	118.9	GO:0070567	cytidylyltransferase activity(GO:0070567)
16.9	101.7	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
16.9	16.9	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
16.8	67.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
16.8	50.5	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
16.8	50.3	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
16.8	268.4	GO:0070064	proline-rich region binding(GO:0070064)
16.7	50.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
16.4	32.9	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
16.3	456.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
16.3	341.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
16.2	48.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
16.1	128.9	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
16.1	144.5	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
15.9	95.5	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
15.9	15.9	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
15.8	79.0	GO:0070324	thyroid hormone binding(GO:0070324)
15.8	110.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
15.8	63.1	GO:0015232	heme transporter activity(GO:0015232)
15.6	78.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
15.6	46.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
15.6	93.4	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
15.5	15.5	GO:0033142	progesterone receptor binding(GO:0033142)
15.4	46.3	GO:0004771	sterol esterase activity(GO:0004771)
15.4	138.7	GO:0008301	DNA binding, bending(GO:0008301)
15.4	138.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
15.3	91.8	GO:0001727	lipid kinase activity(GO:0001727)
15.3	45.9	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
15.2	121.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
15.2	45.5	GO:0042030	ATPase inhibitor activity(GO:0042030)
15.1	60.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
15.1	136.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
15.1	120.5	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
15.0	45.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
15.0	194.8	GO:0010181	FMN binding(GO:0010181)
15.0	15.0	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
14.9	89.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
14.9	44.6	GO:0042296	ISG15 transferase activity(GO:0042296)
14.8	147.7	GO:0051010	microtubule plus-end binding(GO:0051010)
14.7	58.8	GO:0019788	NEDD8 transferase activity(GO:0019788)
14.7	14.7	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
14.5	58.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
14.5	43.5	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
14.5	159.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
14.5	87.0	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
14.5	57.9	GO:0038100	nodal binding(GO:0038100)
14.4	173.4	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
14.4	43.3	GO:0004832	valine-tRNA ligase activity(GO:0004832)
14.4	100.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
14.2	71.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
14.2	71.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
14.2	42.5	GO:0035174	histone serine kinase activity(GO:0035174)
14.2	14.2	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
14.2	155.7	GO:0004407	histone deacetylase activity(GO:0004407)
14.1	14.1	GO:0032452	histone demethylase activity(GO:0032452)
14.1	254.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
14.1	42.3	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
14.1	155.0	GO:0042162	telomeric DNA binding(GO:0042162)
14.1	42.2	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
14.0	14.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
14.0	42.0	GO:0030984	kininogen binding(GO:0030984)
14.0	265.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
13.9	41.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
13.8	55.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
13.8	69.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
13.8	55.3	GO:1990932	5.8S rRNA binding(GO:1990932)
13.8	55.2	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
13.8	41.4	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
13.8	151.6	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
13.7	68.7	GO:0016151	nickel cation binding(GO:0016151)
13.7	54.9	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
13.7	68.5	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
13.6	422.4	GO:0048487	beta-tubulin binding(GO:0048487)
13.6	245.0	GO:0008483	transaminase activity(GO:0008483)
13.5	54.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
13.5	13.5	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
13.5	54.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
13.5	53.9	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
13.5	53.9	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
13.4	40.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
13.4	66.9	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
13.4	53.4	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
13.2	238.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
13.2	39.6	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
13.1	552.3	GO:0043022	ribosome binding(GO:0043022)
13.1	39.4	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
13.1	183.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
13.1	157.0	GO:0070628	proteasome binding(GO:0070628)
13.0	129.5	GO:0004568	chitinase activity(GO:0004568)
12.9	77.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
12.9	12.9	GO:0051434	BH3 domain binding(GO:0051434)
12.9	25.8	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
12.9	51.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
12.8	64.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
12.8	25.7	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
12.8	102.3	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
12.8	242.8	GO:0003746	translation elongation factor activity(GO:0003746)
12.8	191.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
12.6	341.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
12.6	366.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
12.6	25.2	GO:1990239	steroid hormone binding(GO:1990239)
12.6	62.9	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
12.6	364.7	GO:0050699	WW domain binding(GO:0050699)
12.6	25.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
12.5	125.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
12.5	25.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
12.5	112.5	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
12.4	124.4	GO:0001618	virus receptor activity(GO:0001618)
12.4	272.8	GO:0050681	androgen receptor binding(GO:0050681)
12.4	136.2	GO:0030955	potassium ion binding(GO:0030955)
12.4	49.5	GO:0004594	pantothenate kinase activity(GO:0004594)
12.4	61.8	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
12.3	49.4	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
12.3	37.0	GO:1990460	leptin receptor binding(GO:1990460)
12.3	73.7	GO:0050733	RS domain binding(GO:0050733)
12.3	233.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
12.3	49.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
12.3	24.6	GO:0005128	erythropoietin receptor binding(GO:0005128)
12.3	73.7	GO:0004708	MAP kinase kinase activity(GO:0004708)
12.2	134.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
12.2	219.6	GO:0001056	RNA polymerase III activity(GO:0001056)
12.2	109.7	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
12.1	109.3	GO:0008432	JUN kinase binding(GO:0008432)
12.1	121.1	GO:0050811	GABA receptor binding(GO:0050811)
12.1	156.8	GO:0015928	fucosidase activity(GO:0015928)
12.1	24.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
12.0	204.4	GO:0043531	ADP binding(GO:0043531)
12.0	35.9	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
11.9	238.7	GO:0001221	transcription cofactor binding(GO:0001221)
11.9	71.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
11.9	59.4	GO:0070728	leucine binding(GO:0070728)
11.8	47.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
11.8	106.0	GO:0039706	co-receptor binding(GO:0039706)
11.7	493.0	GO:0019209	kinase activator activity(GO:0019209)
11.7	152.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
11.7	23.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
11.6	69.6	GO:0030274	LIM domain binding(GO:0030274)
11.6	34.7	GO:0000339	RNA cap binding(GO:0000339)
11.6	11.6	GO:0032552	deoxyribonucleotide binding(GO:0032552)
11.5	92.3	GO:0043176	amine binding(GO:0043176)
11.5	11.5	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
11.5	298.5	GO:0070063	RNA polymerase binding(GO:0070063)
11.4	57.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
11.4	159.0	GO:0017049	GTP-Rho binding(GO:0017049)
11.3	34.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
11.3	33.9	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
11.3	33.9	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
11.3	112.7	GO:0045295	gamma-catenin binding(GO:0045295)
11.2	33.7	GO:1990226	histone methyltransferase binding(GO:1990226)
11.2	33.7	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
11.2	550.1	GO:0017048	Rho GTPase binding(GO:0017048)
11.2	179.6	GO:0001848	complement binding(GO:0001848)
11.2	56.1	GO:0017040	ceramidase activity(GO:0017040)
11.2	100.8	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
11.2	22.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
11.2	368.9	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812)
11.2	44.7	GO:0097642	calcitonin family receptor activity(GO:0097642)
11.1	244.6	GO:0004177	aminopeptidase activity(GO:0004177)
11.1	111.0	GO:0004602	glutathione peroxidase activity(GO:0004602)
11.1	33.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
11.1	199.2	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
11.1	11.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
11.0	66.0	GO:0043522	leucine zipper domain binding(GO:0043522)
11.0	109.8	GO:0004016	adenylate cyclase activity(GO:0004016)
11.0	54.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
10.9	32.8	GO:0097322	7SK snRNA binding(GO:0097322)
10.9	568.5	GO:0051087	chaperone binding(GO:0051087)
10.9	43.7	GO:0043237	laminin-1 binding(GO:0043237)
10.9	32.8	GO:0030492	hemoglobin binding(GO:0030492)
10.9	98.2	GO:0030983	mismatched DNA binding(GO:0030983)
10.9	43.6	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
10.9	21.8	GO:0070538	oleic acid binding(GO:0070538)
10.9	32.6	GO:0030911	TPR domain binding(GO:0030911)
10.8	97.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
10.8	53.8	GO:0015288	porin activity(GO:0015288)
10.7	75.2	GO:0034046	poly(G) binding(GO:0034046)
10.7	128.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
10.7	32.1	GO:0003696	satellite DNA binding(GO:0003696)
10.7	64.1	GO:0000150	recombinase activity(GO:0000150)
10.7	21.4	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
10.7	224.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
10.7	128.0	GO:0016830	carbon-carbon lyase activity(GO:0016830)
10.7	32.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
10.7	10.7	GO:0008200	ion channel inhibitor activity(GO:0008200)
10.7	42.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
10.6	159.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
10.6	42.5	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
10.6	159.0	GO:0008327	methyl-CpG binding(GO:0008327)
10.6	127.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
10.5	10.5	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
10.5	263.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
10.5	31.5	GO:0031750	D3 dopamine receptor binding(GO:0031750)
10.5	168.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
10.5	73.5	GO:0001671	ATPase activator activity(GO:0001671)
10.5	21.0	GO:0050816	phosphothreonine binding(GO:0050816)
10.5	73.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
10.5	303.4	GO:0016748	succinyltransferase activity(GO:0016748) N-succinyltransferase activity(GO:0016749)
10.4	41.8	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
10.4	73.1	GO:0008430	selenium binding(GO:0008430)
10.4	31.3	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
10.4	93.5	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
10.4	20.7	GO:0043842	Kdo transferase activity(GO:0043842)
10.3	51.5	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
10.3	10.3	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
10.3	925.0	GO:0017137	Rab GTPase binding(GO:0017137)
10.2	41.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
10.2	40.9	GO:0016778	diphosphotransferase activity(GO:0016778)
10.2	20.5	GO:0035877	death effector domain binding(GO:0035877)
10.2	30.6	GO:0004046	aminoacylase activity(GO:0004046)
10.2	81.3	GO:0005123	death receptor binding(GO:0005123)
10.1	172.5	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
10.1	30.4	GO:0032027	myosin light chain binding(GO:0032027)
10.1	90.8	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
10.1	655.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
10.0	70.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
10.0	40.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
10.0	837.2	GO:0008171	O-methyltransferase activity(GO:0008171)
10.0	29.9	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
10.0	119.5	GO:0070008	serine-type exopeptidase activity(GO:0070008)
9.9	129.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
9.9	49.7	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
9.9	9.9	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
9.9	79.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
9.9	9.9	GO:0016418	S-acetyltransferase activity(GO:0016418)
9.9	9.9	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
9.9	9.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
9.9	39.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
9.9	49.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
9.8	29.5	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
9.8	19.6	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
9.8	392.6	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
9.8	49.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
9.8	78.3	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
9.8	29.3	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
9.7	29.2	GO:0071987	WD40-repeat domain binding(GO:0071987)
9.7	272.1	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
9.7	77.4	GO:0003993	acid phosphatase activity(GO:0003993)
9.7	125.7	GO:0008143	poly(A) binding(GO:0008143)
9.6	57.8	GO:0005113	patched binding(GO:0005113)
9.6	86.5	GO:0043024	ribosomal small subunit binding(GO:0043024)
9.6	9.6	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
9.6	325.4	GO:0070491	repressing transcription factor binding(GO:0070491)
9.5	105.0	GO:0017154	semaphorin receptor activity(GO:0017154)
9.5	28.6	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
9.5	28.5	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
9.5	38.0	GO:0036310	annealing helicase activity(GO:0036310)
9.5	66.4	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
9.5	56.9	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
9.5	56.8	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
9.5	37.9	GO:0004966	galanin receptor activity(GO:0004966)
9.4	113.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
9.4	9.4	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
9.4	56.5	GO:0045545	syndecan binding(GO:0045545)
9.4	206.4	GO:0004118	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
9.4	9.4	GO:0000403	Y-form DNA binding(GO:0000403)
9.3	112.0	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
9.3	74.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
9.3	46.6	GO:0071949	FAD binding(GO:0071949)
9.3	612.4	GO:0008565	protein transporter activity(GO:0008565)
9.3	74.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
9.2	83.0	GO:0034871	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
9.1	9.1	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
9.1	18.2	GO:0004945	angiotensin type II receptor activity(GO:0004945)
9.1	9.1	GO:0070698	type I activin receptor binding(GO:0070698)
9.1	54.6	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
9.1	54.5	GO:0008097	5S rRNA binding(GO:0008097)
9.1	36.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
9.0	18.0	GO:0050897	cobalt ion binding(GO:0050897)
9.0	27.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
9.0	449.9	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
9.0	36.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
9.0	35.9	GO:0016413	O-acetyltransferase activity(GO:0016413)
9.0	26.9	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
9.0	44.8	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
9.0	9.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
8.9	80.5	GO:0055102	lipase inhibitor activity(GO:0055102)
8.9	17.8	GO:0017098	sulfonylurea receptor binding(GO:0017098)
8.9	115.8	GO:0015026	coreceptor activity(GO:0015026)
8.9	79.9	GO:0004697	protein kinase C activity(GO:0004697)
8.8	17.7	GO:0004977	melanocortin receptor activity(GO:0004977)
8.8	35.3	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
8.8	61.6	GO:0070182	DNA polymerase binding(GO:0070182)
8.8	35.0	GO:0097157	pre-mRNA intronic binding(GO:0097157)
8.7	43.7	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
8.7	8.7	GO:0034618	arginine binding(GO:0034618)
8.7	8.7	GO:0008142	oxysterol binding(GO:0008142)
8.7	355.8	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
8.7	104.1	GO:0004527	exonuclease activity(GO:0004527)
8.7	34.7	GO:0034185	apolipoprotein binding(GO:0034185)
8.7	17.3	GO:0042134	rRNA primary transcript binding(GO:0042134)
8.7	17.3	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
8.6	441.0	GO:0003697	single-stranded DNA binding(GO:0003697)
8.6	25.9	GO:0055103	ligase regulator activity(GO:0055103)
8.6	395.5	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
8.6	8.6	GO:0003916	DNA topoisomerase activity(GO:0003916)
8.6	8.6	GO:0004887	thyroid hormone receptor activity(GO:0004887)
8.6	8.6	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
8.6	25.7	GO:0070569	uridylyltransferase activity(GO:0070569)
8.5	102.5	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
8.5	392.1	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
8.5	25.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
8.4	76.0	GO:0002039	p53 binding(GO:0002039)
8.4	16.9	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
8.4	75.8	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
8.4	8.4	GO:0000009	alpha-1,6-mannosyltransferase activity(GO:0000009)
8.4	108.6	GO:0000049	tRNA binding(GO:0000049)
8.3	16.6	GO:1990188	euchromatin binding(GO:1990188)
8.3	199.7	GO:0003684	damaged DNA binding(GO:0003684)
8.3	74.8	GO:0019841	retinol binding(GO:0019841)
8.3	58.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
8.3	66.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
8.2	16.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
8.2	33.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
8.2	90.5	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
8.2	24.6	GO:0004305	ethanolamine kinase activity(GO:0004305)
8.2	8.2	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
8.2	8.2	GO:0003933	GTP cyclohydrolase activity(GO:0003933) cyclohydrolase activity(GO:0019238)
8.1	105.9	GO:0008252	nucleotidase activity(GO:0008252)
8.1	24.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
8.1	16.3	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
8.1	81.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
8.1	40.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
8.1	8.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
8.1	32.2	GO:0042015	interleukin-20 binding(GO:0042015)
8.1	56.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
8.0	40.2	GO:1990405	protein antigen binding(GO:1990405)
8.0	16.0	GO:0015377	cation:chloride symporter activity(GO:0015377)
8.0	96.1	GO:0008198	ferrous iron binding(GO:0008198)
8.0	56.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
8.0	24.0	GO:1990446	U1 snRNP binding(GO:1990446)
8.0	40.0	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
8.0	39.9	GO:0004457	lactate dehydrogenase activity(GO:0004457)
8.0	8.0	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
8.0	477.0	GO:0004540	ribonuclease activity(GO:0004540)
7.9	127.2	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
7.9	7.9	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
7.9	15.8	GO:0070061	fructose binding(GO:0070061)
7.9	39.4	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
7.9	31.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
7.9	196.6	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
7.8	7.8	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
7.8	23.5	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
7.8	23.4	GO:0008174	mRNA methyltransferase activity(GO:0008174)
7.8	62.4	GO:0031996	thioesterase binding(GO:0031996)
7.7	30.9	GO:0001055	RNA polymerase II activity(GO:0001055)
7.7	292.2	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
7.7	23.0	GO:0071209	U7 snRNA binding(GO:0071209)
7.7	53.6	GO:0048406	nerve growth factor binding(GO:0048406)
7.6	137.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
7.6	22.9	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
7.6	76.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
7.6	15.2	GO:0019789	SUMO transferase activity(GO:0019789)
7.6	38.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
7.6	227.9	GO:0031593	polyubiquitin binding(GO:0031593)
7.6	30.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
7.5	128.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
7.5	37.7	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
7.5	180.4	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
7.5	22.5	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
7.5	44.9	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
7.4	81.6	GO:0030145	manganese ion binding(GO:0030145)
7.4	14.8	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
7.4	29.7	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
7.4	22.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
7.4	22.1	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
7.4	51.6	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
7.4	29.4	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
7.3	51.4	GO:0050321	tau-protein kinase activity(GO:0050321)
7.3	29.3	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
7.3	219.8	GO:0004402	histone acetyltransferase activity(GO:0004402)
7.3	65.8	GO:0008536	Ran GTPase binding(GO:0008536)
7.3	349.7	GO:0016836	hydro-lyase activity(GO:0016836)
7.3	51.0	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
7.3	21.8	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
7.3	123.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
7.2	14.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
7.2	14.4	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
7.1	14.3	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
7.1	14.3	GO:0042577	lipid phosphatase activity(GO:0042577)
7.1	299.7	GO:0008168	methyltransferase activity(GO:0008168)
7.1	917.6	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
7.1	14.2	GO:0046848	hydroxyapatite binding(GO:0046848)
7.1	21.3	GO:0019213	deacetylase activity(GO:0019213)
7.1	7.1	GO:0051380	norepinephrine binding(GO:0051380)
7.1	28.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
7.1	642.7	GO:0019902	phosphatase binding(GO:0019902)
7.0	7.0	GO:0036033	mediator complex binding(GO:0036033)
7.0	98.0	GO:0001530	lipopolysaccharide binding(GO:0001530)
7.0	132.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
7.0	76.6	GO:0030552	cAMP binding(GO:0030552)
7.0	34.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
6.9	13.9	GO:1990825	sequence-specific mRNA binding(GO:1990825)
6.9	13.9	GO:0051373	FATZ binding(GO:0051373)
6.9	97.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
6.9	27.6	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
6.9	96.1	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
6.8	27.4	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
6.8	34.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
6.8	81.9	GO:0033613	activating transcription factor binding(GO:0033613)
6.8	13.6	GO:1990715	mRNA CDS binding(GO:1990715)
6.8	183.7	GO:0005484	SNAP receptor activity(GO:0005484)
6.8	61.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
6.8	115.3	GO:0030515	snoRNA binding(GO:0030515)
6.8	6.8	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
6.8	6.8	GO:0017081	chloride channel regulator activity(GO:0017081)
6.7	33.7	GO:0008251	tRNA-specific adenosine deaminase activity(GO:0008251)
6.7	13.5	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
6.7	93.7	GO:0031489	myosin V binding(GO:0031489)
6.7	46.9	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
6.7	133.4	GO:0043130	ubiquitin binding(GO:0043130)
6.7	6.7	GO:0052744	phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
6.6	19.9	GO:0005000	vasopressin receptor activity(GO:0005000)
6.6	6.6	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
6.6	26.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
6.6	13.2	GO:0008147	structural constituent of bone(GO:0008147)
6.6	13.2	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
6.6	164.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
6.6	702.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
6.5	13.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
6.5	26.0	GO:0045294	alpha-catenin binding(GO:0045294)
6.5	19.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
6.5	32.4	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
6.5	32.4	GO:0001054	RNA polymerase I activity(GO:0001054)
6.4	109.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
6.4	442.7	GO:0017124	SH3 domain binding(GO:0017124)
6.4	108.9	GO:0051059	NF-kappaB binding(GO:0051059)
6.4	25.6	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
6.4	38.2	GO:0051011	microtubule minus-end binding(GO:0051011)
6.3	31.6	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
6.3	12.6	GO:0030621	U4 snRNA binding(GO:0030621)
6.3	6.3	GO:0034061	DNA polymerase activity(GO:0034061)
6.3	37.7	GO:0004630	phospholipase D activity(GO:0004630)
6.3	18.8	GO:0043008	ATP-dependent protein binding(GO:0043008)
6.3	6.3	GO:0016866	intramolecular transferase activity(GO:0016866)
6.2	18.7	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
6.2	24.9	GO:0010997	anaphase-promoting complex binding(GO:0010997)
6.2	74.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
6.1	18.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
6.1	6.1	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
6.1	18.3	GO:0004385	guanylate kinase activity(GO:0004385)
6.1	18.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
6.1	6.1	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
6.1	79.0	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
6.1	54.7	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
6.1	24.3	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
6.1	18.2	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
6.0	6.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
6.0	18.1	GO:0004995	tachykinin receptor activity(GO:0004995)
6.0	84.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
6.0	48.1	GO:0051018	protein kinase A binding(GO:0051018)
6.0	12.0	GO:0000182	rDNA binding(GO:0000182)
6.0	53.9	GO:0032182	ubiquitin-like protein binding(GO:0032182)
6.0	53.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
5.9	77.3	GO:0031369	translation initiation factor binding(GO:0031369)
5.9	65.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
5.9	17.8	GO:0048030	disaccharide binding(GO:0048030)
5.9	11.8	GO:0004672	protein kinase activity(GO:0004672)
5.9	65.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
5.9	5.9	GO:0015197	peptide transporter activity(GO:0015197)
5.8	5.8	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
5.8	11.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
5.8	227.0	GO:0008234	cysteine-type peptidase activity(GO:0008234)
5.8	34.8	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
5.8	46.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
5.8	11.5	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
5.7	23.0	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
5.7	51.6	GO:0004383	guanylate cyclase activity(GO:0004383)
5.7	28.7	GO:0050700	CARD domain binding(GO:0050700)
5.7	96.9	GO:0008201	heparin binding(GO:0008201)
5.7	22.8	GO:0019203	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
5.7	11.4	GO:0016853	isomerase activity(GO:0016853)
5.7	22.8	GO:0004370	glycerol kinase activity(GO:0004370)
5.7	11.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
5.7	17.0	GO:0019767	IgE receptor activity(GO:0019767)
5.7	5.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
5.7	33.9	GO:0031386	protein tag(GO:0031386)
5.6	242.1	GO:0008417	fucosyltransferase activity(GO:0008417)
5.6	44.9	GO:0030742	GTP-dependent protein binding(GO:0030742)
5.6	11.2	GO:0032036	myosin heavy chain binding(GO:0032036)
5.6	67.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
5.6	27.9	GO:0005412	glucose:sodium symporter activity(GO:0005412)
5.6	83.8	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(GO:0016818)
5.6	133.5	GO:0015485	cholesterol binding(GO:0015485)
5.5	11.1	GO:0038132	neuregulin binding(GO:0038132)
5.5	27.7	GO:0008420	CTD phosphatase activity(GO:0008420)
5.5	16.6	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
5.5	22.0	GO:0004000	adenosine deaminase activity(GO:0004000)
5.5	16.5	GO:0004645	phosphorylase activity(GO:0004645)
5.5	5.5	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
5.5	16.5	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
5.5	11.0	GO:0019776	Atg8 ligase activity(GO:0019776)
5.5	11.0	GO:0070052	collagen V binding(GO:0070052)
5.5	54.7	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
5.5	120.2	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
5.4	5.4	GO:0035325	Toll-like receptor binding(GO:0035325) Toll-like receptor 4 binding(GO:0035662)
5.4	146.4	GO:0003725	double-stranded RNA binding(GO:0003725)
5.4	48.8	GO:0051879	Hsp90 protein binding(GO:0051879)
5.4	32.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
5.4	436.1	GO:0003714	transcription corepressor activity(GO:0003714)
5.4	16.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
5.4	10.8	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
5.4	32.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
5.4	26.8	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
5.4	10.7	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
5.3	10.7	GO:0043515	kinetochore binding(GO:0043515)
5.3	181.5	GO:0004518	nuclease activity(GO:0004518)
5.3	58.7	GO:0017091	AU-rich element binding(GO:0017091)
5.3	26.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
5.3	26.5	GO:0017025	TBP-class protein binding(GO:0017025)
5.3	37.0	GO:0017166	vinculin binding(GO:0017166)
5.3	5.3	GO:0030545	receptor regulator activity(GO:0030545)
5.3	152.6	GO:0005507	copper ion binding(GO:0005507)
5.3	42.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
5.2	62.8	GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
5.2	31.4	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
5.2	26.0	GO:0005499	vitamin D binding(GO:0005499)
5.2	10.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
5.2	10.4	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
5.1	51.5	GO:0043015	gamma-tubulin binding(GO:0043015)
5.1	15.4	GO:0031014	troponin T binding(GO:0031014)
5.1	5.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
5.1	35.9	GO:0032451	demethylase activity(GO:0032451)
5.1	187.6	GO:0042826	histone deacetylase binding(GO:0042826)
5.1	5.1	GO:0045182	translation regulator activity(GO:0045182)
5.0	1046.8	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
5.0	854.6	GO:0003735	structural constituent of ribosome(GO:0003735)
5.0	50.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
5.0	45.1	GO:0004622	lysophospholipase activity(GO:0004622)
5.0	250.4	GO:0004896	cytokine receptor activity(GO:0004896)
5.0	154.9	GO:0003743	translation initiation factor activity(GO:0003743)
5.0	19.9	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
5.0	224.0	GO:0000149	SNARE binding(GO:0000149)
5.0	64.6	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
5.0	84.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
5.0	9.9	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
5.0	163.4	GO:0042562	hormone binding(GO:0042562)
4.9	44.5	GO:0022821	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
4.9	19.6	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
4.9	98.0	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
4.9	4.9	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
4.9	4.9	GO:0008061	chitin binding(GO:0008061)
4.8	150.2	GO:0015923	mannosidase activity(GO:0015923)
4.8	130.4	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
4.8	24.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
4.8	19.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
4.8	9.6	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
4.8	243.4	GO:0043492	ATPase activity, coupled to movement of substances(GO:0043492)
4.8	142.7	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
4.8	9.5	GO:0016841	ammonia-lyase activity(GO:0016841)
4.7	61.7	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
4.7	56.8	GO:0090484	drug transporter activity(GO:0090484)
4.7	89.6	GO:0043621	protein self-association(GO:0043621)
4.7	47.0	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
4.7	51.6	GO:0004175	endopeptidase activity(GO:0004175)
4.7	46.6	GO:0005523	tropomyosin binding(GO:0005523)
4.7	4.7	GO:0019863	IgE binding(GO:0019863)
4.6	13.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)
4.6	13.9	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
4.6	51.0	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
4.6	92.7	GO:0051082	unfolded protein binding(GO:0051082)
4.6	18.5	GO:0070566	adenylyltransferase activity(GO:0070566)
4.6	4.6	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
4.6	13.8	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
4.6	23.0	GO:0004180	carboxypeptidase activity(GO:0004180)
4.6	18.4	GO:0019966	interleukin-1 binding(GO:0019966)
4.6	4.6	GO:0051213	dioxygenase activity(GO:0051213)
4.6	22.9	GO:0000287	magnesium ion binding(GO:0000287)
4.6	2434.2	GO:0044822	poly(A) RNA binding(GO:0044822)
4.6	18.3	GO:0070513	death domain binding(GO:0070513)
4.6	500.6	GO:0005096	GTPase activator activity(GO:0005096)
4.5	117.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
4.5	121.6	GO:0047485	protein N-terminus binding(GO:0047485)
4.5	18.0	GO:0048038	quinone binding(GO:0048038)
4.5	4.5	GO:0036222	dITP diphosphatase activity(GO:0035870) XTP diphosphatase activity(GO:0036222)
4.4	17.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
4.4	8.9	GO:0005534	galactose binding(GO:0005534)
4.4	35.5	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
4.4	22.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
4.4	13.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
4.4	4.4	GO:0034452	dynactin binding(GO:0034452)
4.4	8.8	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
4.4	17.5	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
4.4	39.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
4.4	13.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
4.3	30.3	GO:0017160	Ral GTPase binding(GO:0017160)
4.3	43.3	GO:0005158	insulin receptor binding(GO:0005158)
4.3	4.3	GO:0019862	IgA binding(GO:0019862)
4.3	8.5	GO:0015250	water channel activity(GO:0015250)
4.3	4.3	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
4.2	42.3	GO:0070888	E-box binding(GO:0070888)
4.2	126.7	GO:0005132	type I interferon receptor binding(GO:0005132)
4.2	46.3	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
4.2	25.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
4.2	4.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
4.2	12.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
4.2	20.9	GO:0031849	olfactory receptor binding(GO:0031849)
4.2	16.7	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
4.2	183.6	GO:0016791	phosphatase activity(GO:0016791)
4.2	4.2	GO:0016783	sulfurtransferase activity(GO:0016783)
4.2	4.2	GO:0016015	morphogen activity(GO:0016015)
4.1	29.0	GO:0031491	nucleosome binding(GO:0031491)
4.1	24.7	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
4.1	102.9	GO:0016887	ATPase activity(GO:0016887)
4.1	834.3	GO:0046982	protein heterodimerization activity(GO:0046982)
4.1	8.2	GO:0009975	cyclase activity(GO:0009975)
4.1	20.5	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
4.1	164.1	GO:0001047	core promoter binding(GO:0001047)
4.1	352.2	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
4.1	16.2	GO:0016421	CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
4.0	60.3	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
4.0	8.0	GO:0051185	coenzyme transporter activity(GO:0051185)
4.0	16.0	GO:0016779	nucleotidyltransferase activity(GO:0016779)
4.0	16.0	GO:0019888	protein phosphatase regulator activity(GO:0019888)
4.0	307.3	GO:0003774	motor activity(GO:0003774)
4.0	79.6	GO:0042605	peptide antigen binding(GO:0042605)
4.0	39.6	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
4.0	110.8	GO:0050840	extracellular matrix binding(GO:0050840)
4.0	19.8	GO:0005319	lipid transporter activity(GO:0005319)
3.9	11.8	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
3.9	11.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
3.9	11.7	GO:0042043	neurexin family protein binding(GO:0042043)
3.9	38.8	GO:0042805	actinin binding(GO:0042805)
3.8	72.4	GO:0005212	structural constituent of eye lens(GO:0005212)
3.8	462.6	GO:0003723	RNA binding(GO:0003723)
3.8	41.6	GO:0004364	glutathione transferase activity(GO:0004364)
3.8	3.8	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
3.8	7.5	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
3.7	223.0	GO:0003712	transcription cofactor activity(GO:0003712)
3.7	25.9	GO:0003796	lysozyme activity(GO:0003796)
3.7	3.7	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
3.7	7.4	GO:0043199	sulfate binding(GO:0043199)
3.7	22.0	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
3.7	43.8	GO:0004386	helicase activity(GO:0004386)
3.6	3.6	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
3.6	36.3	GO:0043566	structure-specific DNA binding(GO:0043566)
3.6	54.1	GO:0004623	phospholipase A2 activity(GO:0004623)
3.6	139.5	GO:0042393	histone binding(GO:0042393)
3.5	24.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
3.5	35.0	GO:0004745	retinol dehydrogenase activity(GO:0004745)
3.5	292.2	GO:0004857	enzyme inhibitor activity(GO:0004857)
3.5	1126.6	GO:0042802	identical protein binding(GO:0042802)
3.5	41.4	GO:0042578	phosphoric ester hydrolase activity(GO:0042578)
3.4	41.3	GO:0005539	glycosaminoglycan binding(GO:0005539)
3.4	153.5	GO:0005262	calcium channel activity(GO:0005262)
3.4	346.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
3.4	6.8	GO:0015643	toxic substance binding(GO:0015643)
3.4	6.8	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
3.3	53.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
3.3	19.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
3.3	23.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
3.3	3.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
3.2	54.9	GO:0030674	protein binding, bridging(GO:0030674)
3.2	19.2	GO:0019865	immunoglobulin binding(GO:0019865)
3.2	389.5	GO:0019900	kinase binding(GO:0019900)
3.2	3.2	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
3.2	28.5	GO:0004955	prostaglandin receptor activity(GO:0004955)
3.2	6.3	GO:0000104	succinate dehydrogenase activity(GO:0000104)
3.1	37.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
3.1	6.2	GO:0001595	angiotensin receptor activity(GO:0001595)
3.1	43.4	GO:0000988	transcription factor activity, protein binding(GO:0000988)
3.1	21.4	GO:0015464	acetylcholine receptor activity(GO:0015464)
3.0	3.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
3.0	130.3	GO:0044389	ubiquitin-like protein ligase binding(GO:0044389)
3.0	287.0	GO:0000987	core promoter proximal region sequence-specific DNA binding(GO:0000987)
2.9	26.5	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
2.9	82.3	GO:0005496	steroid binding(GO:0005496)
2.9	137.2	GO:0046983	protein dimerization activity(GO:0046983)
2.9	5.8	GO:0002046	opsin binding(GO:0002046)
2.9	5.8	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
2.9	5.7	GO:0003987	acetate-CoA ligase activity(GO:0003987)
2.9	14.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.9	80.1	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.8	22.8	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
2.8	5.7	GO:0042301	phosphate ion binding(GO:0042301)
2.8	19.6	GO:0016878	acid-thiol ligase activity(GO:0016878)
2.8	16.6	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
2.8	22.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
2.7	71.1	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
2.7	10.9	GO:0051766	inositol trisphosphate kinase activity(GO:0051766)
2.7	455.9	GO:0005525	GTP binding(GO:0005525)
2.6	31.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
2.6	2.6	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
2.6	7.8	GO:1901677	phosphate transmembrane transporter activity(GO:1901677)
2.6	5.2	GO:0034235	GPI anchor binding(GO:0034235)
2.6	13.0	GO:0042288	MHC class I protein binding(GO:0042288)
2.6	224.9	GO:0019904	protein domain specific binding(GO:0019904)
2.6	10.2	GO:0019200	carbohydrate kinase activity(GO:0019200)
2.5	7.6	GO:0061135	endopeptidase regulator activity(GO:0061135)
2.5	2.5	GO:0019763	immunoglobulin receptor activity(GO:0019763)
2.5	196.3	GO:0003682	chromatin binding(GO:0003682)
2.5	42.7	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.5	7.4	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.4	2.4	GO:0042809	vitamin D receptor binding(GO:0042809)
2.4	2.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
2.4	12.1	GO:0061134	peptidase regulator activity(GO:0061134)
2.4	7.2	GO:0035326	enhancer binding(GO:0035326)
2.4	333.8	GO:0046872	metal ion binding(GO:0046872)
2.4	7.1	GO:0016209	antioxidant activity(GO:0016209)
2.4	283.6	GO:0005509	calcium ion binding(GO:0005509)
2.4	4.7	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
2.3	18.7	GO:0005272	sodium channel activity(GO:0005272)
2.3	9.3	GO:0004985	opioid receptor activity(GO:0004985)
2.3	20.9	GO:0051117	ATPase binding(GO:0051117)
2.3	4.6	GO:0016018	cyclosporin A binding(GO:0016018)
2.3	18.3	GO:0004312	fatty acid synthase activity(GO:0004312)
2.3	1187.9	GO:0003676	nucleic acid binding(GO:0003676)
2.2	4.5	GO:0042056	chemoattractant activity(GO:0042056)
2.2	2.2	GO:0019534	toxin transporter activity(GO:0019534)
2.2	24.1	GO:0005537	mannose binding(GO:0005537)
2.2	21.8	GO:0008080	N-acetyltransferase activity(GO:0008080)
2.2	169.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
2.2	4.3	GO:0016415	octanoyltransferase activity(GO:0016415)
2.1	38.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
2.1	4.2	GO:0004673	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
2.1	2.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
2.0	2.0	GO:0004461	lactose synthase activity(GO:0004461)
2.0	6.1	GO:0019842	vitamin binding(GO:0019842)
2.0	59.6	GO:0020037	heme binding(GO:0020037)
2.0	277.1	GO:0017171	serine hydrolase activity(GO:0017171)
2.0	413.0	GO:0008270	zinc ion binding(GO:0008270)
1.9	1.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
1.9	16.9	GO:0022842	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
1.9	7.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
1.8	133.5	GO:0005524	ATP binding(GO:0005524)
1.8	3.7	GO:0019855	calcium channel inhibitor activity(GO:0019855)
1.8	102.9	GO:0030246	carbohydrate binding(GO:0030246)
1.8	28.8	GO:0008134	transcription factor binding(GO:0008134)
1.8	7.2	GO:0051183	vitamin transporter activity(GO:0051183)
1.8	33.6	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
1.7	48.9	GO:0004872	receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
1.7	1.7	GO:0035257	nuclear hormone receptor binding(GO:0035257)
1.7	5.2	GO:0003823	antigen binding(GO:0003823)
1.7	11.9	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.7	1.7	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.7	151.7	GO:0005550	pheromone binding(GO:0005550)
1.7	2734.2	GO:0005515	protein binding(GO:0005515)
1.6	1.6	GO:0008410	CoA-transferase activity(GO:0008410)
1.6	6.5	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
1.6	25.6	GO:0016790	thiolester hydrolase activity(GO:0016790)
1.6	1.6	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
1.5	15.3	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
1.5	1.5	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.4	31.4	GO:0008514	organic anion transmembrane transporter activity(GO:0008514)
1.4	2.8	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.4	1.4	GO:0005227	calcium activated cation channel activity(GO:0005227)
1.4	10.9	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
1.3	103.3	GO:0008289	lipid binding(GO:0008289)
1.3	5.3	GO:0004974	leukotriene receptor activity(GO:0004974)
1.3	3.9	GO:0016773	phosphotransferase activity, alcohol group as acceptor(GO:0016773)
1.3	28.6	GO:0015103	inorganic anion transmembrane transporter activity(GO:0015103)
1.3	1.3	GO:0038181	bile acid receptor activity(GO:0038181)
1.3	1.3	GO:0004954	prostanoid receptor activity(GO:0004954)
1.2	2.4	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.2	1.2	GO:0015927	trehalase activity(GO:0015927)
1.2	1.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
1.2	1297.9	GO:0004984	olfactory receptor activity(GO:0004984)
1.0	3.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
1.0	24.3	GO:0000166	nucleotide binding(GO:0000166) nucleoside phosphate binding(GO:1901265)
0.9	13.8	GO:0001594	trace-amine receptor activity(GO:0001594)
0.9	0.9	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.8	2.4	GO:0008509	anion transmembrane transporter activity(GO:0008509)
0.8	9.3	GO:0016247	channel regulator activity(GO:0016247)
0.6	116.6	GO:0004871	signal transducer activity(GO:0004871)
0.5	34.7	GO:0005215	transporter activity(GO:0005215)
0.5	2.9	GO:0008932	lytic endotransglycosylase activity(GO:0008932)
0.5	0.9	GO:0008144	drug binding(GO:0008144)
0.4	9.7	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)
0.4	37.8	GO:0005198	structural molecule activity(GO:0005198)
0.4	1.5	GO:0004556	alpha-amylase activity(GO:0004556)
0.1	0.8	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.2	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
34.9	488.9	PID IL5 PATHWAY	IL5-mediated signaling events
27.5	826.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
27.0	296.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
19.4	77.4	ST STAT3 PATHWAY	STAT3 Pathway
18.8	470.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
18.7	615.7	PID ARF6 PATHWAY	Arf6 signaling events
18.5	443.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
17.7	194.5	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
16.6	199.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
16.5	990.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
16.4	82.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
16.2	129.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
16.1	80.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
16.0	415.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
15.5	216.3	PID IGF1 PATHWAY	IGF1 pathway
14.9	133.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
14.8	191.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
14.7	132.4	PID EPO PATHWAY	EPO signaling pathway
14.6	248.9	PID ARF 3PATHWAY	Arf1 pathway
14.6	43.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
14.5	320.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
14.4	158.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
13.9	320.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
13.9	332.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
13.7	425.7	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
13.7	370.1	PID RHOA PATHWAY	RhoA signaling pathway
13.4	13.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
13.4	401.6	PID ATR PATHWAY	ATR signaling pathway
12.8	256.3	PID AURORA A PATHWAY	Aurora A signaling
12.8	589.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
12.7	698.8	PID CMYB PATHWAY	C-MYB transcription factor network
12.6	339.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
12.4	62.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
12.3	24.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
12.1	289.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
12.0	132.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
11.9	417.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
11.9	570.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
11.9	47.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
11.7	23.5	ST GAQ PATHWAY	G alpha q Pathway
11.6	46.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
11.1	78.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
10.7	117.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
10.7	10.7	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
10.5	146.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
10.3	351.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
10.2	50.9	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
10.2	111.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
10.1	80.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
10.0	90.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
10.0	79.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
9.9	248.7	PID PLK1 PATHWAY	PLK1 signaling events
9.9	89.0	PID BARD1 PATHWAY	BARD1 signaling events
9.8	107.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
9.6	133.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
9.5	294.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
9.5	161.2	PID TNF PATHWAY	TNF receptor signaling pathway
9.4	150.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
9.3	102.1	PID IFNG PATHWAY	IFN-gamma pathway
9.2	73.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
9.2	45.9	PID IL3 PATHWAY	IL3-mediated signaling events
9.2	605.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
9.0	171.8	PID FOXO PATHWAY	FoxO family signaling
8.9	26.7	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
8.8	396.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
8.8	26.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
8.6	120.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
8.6	284.1	PID E2F PATHWAY	E2F transcription factor network
8.5	93.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
8.5	136.0	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
8.5	110.4	PID ERBB4 PATHWAY	ErbB4 signaling events
8.4	185.8	PID LKB1 PATHWAY	LKB1 signaling events
8.4	100.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
8.2	57.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
8.1	40.7	PID IL2 1PATHWAY	IL2-mediated signaling events
8.0	56.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
8.0	152.6	PID CONE PATHWAY	Visual signal transduction: Cones
8.0	120.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
8.0	16.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
8.0	183.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
7.9	71.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
7.8	117.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
7.8	38.8	PID ATM PATHWAY	ATM pathway
7.7	84.2	PID CDC42 PATHWAY	CDC42 signaling events
7.7	107.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
7.3	146.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
7.2	108.0	PID P53 REGULATION PATHWAY	p53 pathway
6.9	125.0	PID IL12 2PATHWAY	IL12-mediated signaling events
6.8	13.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
6.7	40.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
6.7	141.0	PID AURORA B PATHWAY	Aurora B signaling
6.6	13.2	SIG CHEMOTAXIS	Genes related to chemotaxis
6.5	98.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
6.5	32.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
6.5	135.8	PID P73PATHWAY	p73 transcription factor network
6.5	64.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
6.4	51.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
6.3	107.4	PID ILK PATHWAY	Integrin-linked kinase signaling
6.2	18.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
6.2	210.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
6.1	128.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
5.9	64.8	PID IL1 PATHWAY	IL1-mediated signaling events
5.8	58.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
5.8	17.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
5.6	50.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
5.6	156.4	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
5.6	5.6	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
5.5	60.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
5.4	37.7	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
5.3	89.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
5.2	103.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
5.1	35.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
5.0	25.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
4.8	62.7	PID RAS PATHWAY	Regulation of Ras family activation
4.8	85.9	PID MTOR 4PATHWAY	mTOR signaling pathway
4.7	23.6	ST G ALPHA S PATHWAY	G alpha s Pathway
4.7	28.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
4.5	4.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
4.3	21.7	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
4.3	64.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
4.3	55.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
4.2	193.2	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
4.2	54.1	PID AP1 PATHWAY	AP-1 transcription factor network
4.1	28.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
4.1	8.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
3.9	34.9	PID IL23 PATHWAY	IL23-mediated signaling events
3.8	34.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
3.8	26.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
3.7	44.6	PID FANCONI PATHWAY	Fanconi anemia pathway
3.6	10.9	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
3.6	678.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
3.6	42.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
3.4	10.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
3.4	27.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.4	41.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
3.4	13.6	PID ALK2 PATHWAY	ALK2 signaling events
3.4	30.4	PID RAC1 PATHWAY	RAC1 signaling pathway
3.3	20.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
3.3	26.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
3.3	6.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
3.3	32.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
3.1	40.8	PID IL4 2PATHWAY	IL4-mediated signaling events
3.1	18.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
2.9	5.8	PID TRAIL PATHWAY	TRAIL signaling pathway
2.7	361.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.6	26.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
2.6	41.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
2.5	5.1	PID CD40 PATHWAY	CD40/CD40L signaling
2.5	24.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
2.3	23.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
2.3	58.0	PID BMP PATHWAY	BMP receptor signaling
2.3	18.6	PID BCR 5PATHWAY	BCR signaling pathway
2.3	29.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
2.3	11.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.3	6.8	PID IL27 PATHWAY	IL27-mediated signaling events
2.1	19.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
1.9	11.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.9	11.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
1.8	3.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.8	1.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.7	3.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.7	6.6	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.6	9.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.6	11.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
1.5	11.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.3	6.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
1.2	9.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
1.2	13.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
1.2	207.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
1.1	2.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
1.1	13.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
1.0	1.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.9	0.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.7	112.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
66.3	927.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
53.0	635.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
48.9	489.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
45.0	449.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
43.5	391.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
34.9	34.9	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
34.2	376.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
33.5	100.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
33.1	562.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
31.9	255.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
30.8	307.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
28.9	434.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
28.8	28.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
28.5	342.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
28.2	225.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
26.7	186.9	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
26.3	263.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
24.3	97.1	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
22.3	513.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
22.3	178.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
22.1	154.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
21.6	86.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
19.8	535.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
19.8	158.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
19.5	175.7	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
18.8	169.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
18.7	393.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
18.5	332.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
18.0	72.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
17.7	673.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
17.5	244.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
17.2	344.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
17.2	257.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
17.1	188.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
17.1	291.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
16.9	67.7	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
16.8	100.9	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
16.2	97.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
15.9	461.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
15.9	111.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
15.7	392.6	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
15.5	200.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
15.4	416.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
15.3	45.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
15.3	45.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
15.2	213.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
15.2	213.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
15.1	166.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
15.0	676.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
15.0	403.7	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
14.9	148.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
14.7	219.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
14.4	114.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
14.2	184.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
14.2	85.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
14.1	127.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
14.1	42.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
14.0	308.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
14.0	153.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
13.6	13.6	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
13.5	406.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
13.5	27.0	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
13.5	94.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
13.5	188.7	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
13.4	120.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
13.4	173.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
13.3	106.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
13.2	290.7	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
13.2	52.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
13.1	196.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
13.0	325.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
12.8	653.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
12.8	369.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
12.6	37.9	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
12.5	374.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
12.3	503.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
12.2	12.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
12.2	972.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
12.1	278.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
12.1	60.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
12.1	144.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
11.9	11.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
11.7	35.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
11.7	58.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
11.6	69.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
11.5	23.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
11.5	92.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
11.4	262.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
11.3	22.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
11.3	11.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
11.3	11.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
11.2	280.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
11.2	55.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
11.1	211.1	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
11.1	122.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
11.0	308.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
10.9	328.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
10.9	119.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
10.8	53.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
10.8	183.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
10.7	21.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
10.7	107.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
10.6	170.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
10.6	190.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
10.5	10.5	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
10.5	231.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
10.5	231.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
10.5	84.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
10.5	104.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
10.2	81.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
10.1	60.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
10.1	10.1	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
10.1	596.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
10.1	181.0	REACTOME G1 PHASE	Genes involved in G1 Phase
10.0	338.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
10.0	109.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
10.0	567.4	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
9.9	138.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
9.8	108.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
9.7	9.7	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
9.6	124.7	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
9.4	9.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
9.3	204.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
9.1	73.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
9.1	72.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
9.1	99.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
9.0	81.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
9.0	45.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
9.0	483.7	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
8.8	52.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
8.8	123.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
8.7	96.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
8.7	445.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
8.5	136.4	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
8.5	271.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
8.5	50.8	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
8.4	226.2	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
8.2	155.9	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
8.1	48.8	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
8.1	161.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
8.1	88.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
8.1	64.4	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
8.0	263.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
7.9	103.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
7.9	23.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
7.9	70.7	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
7.8	46.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
7.7	61.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
7.7	38.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
7.7	199.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
7.6	38.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
7.5	900.8	REACTOME TRANSLATION	Genes involved in Translation
7.5	29.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
7.4	73.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
7.4	51.6	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
7.2	7.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
7.2	72.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
7.2	36.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
7.2	7.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
7.2	71.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
7.2	271.8	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
7.1	77.9	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
7.1	7.1	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
7.0	77.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
7.0	530.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
6.9	27.7	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
6.9	110.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
6.9	179.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
6.9	68.6	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
6.8	191.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
6.7	777.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
6.7	53.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
6.6	106.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
6.6	604.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
6.5	71.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
6.5	51.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
6.4	6.4	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
6.2	43.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
6.1	61.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
6.1	36.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
6.0	144.2	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
5.9	41.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
5.9	17.6	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
5.6	16.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
5.6	61.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
5.6	33.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
5.6	111.5	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
5.6	61.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
5.5	60.4	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
5.5	93.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
5.4	43.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
5.4	135.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
5.4	48.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
5.4	225.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
5.3	42.8	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
5.3	73.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
5.2	26.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
5.2	327.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
5.1	15.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
5.1	127.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
5.1	71.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
5.1	35.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
5.0	55.5	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
5.0	34.7	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
4.9	14.8	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.8	58.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
4.7	52.0	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
4.7	9.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
4.6	13.8	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
4.5	184.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
4.4	8.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
4.4	175.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
4.1	66.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
4.1	49.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
4.0	67.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
3.9	74.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
3.8	3.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
3.8	57.0	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
3.8	26.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
3.8	71.9	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
3.8	33.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
3.7	138.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
3.7	11.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
3.6	21.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
3.6	39.6	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
3.6	49.9	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
3.5	20.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
3.4	13.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
3.4	13.7	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
3.4	44.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
3.4	71.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
3.4	23.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
3.3	3.3	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
3.3	16.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
3.2	9.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
3.2	35.3	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
3.2	19.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
3.1	44.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
3.1	37.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
3.1	6.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
3.1	3.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
3.0	304.5	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
2.9	23.5	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
2.9	17.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
2.8	13.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
2.8	16.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
2.7	13.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
2.7	38.4	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
2.7	21.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
2.6	150.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
2.5	25.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
2.4	2.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
2.4	33.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
2.4	30.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
2.3	6.9	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
2.3	2.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
2.2	8.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.9	14.8	REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR	Genes involved in Downstream signaling of activated FGFR
1.8	26.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
1.8	1.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.8	67.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
1.6	8.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
1.5	52.3	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
1.4	28.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
1.4	6.8	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.3	2.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.3	1.3	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
1.1	1.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.1	17.6	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
1.1	2.2	REACTOME CELL CYCLE MITOTIC	Genes involved in Cell Cycle, Mitotic
1.0	12.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.0	3.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
1.0	2.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.0	1.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.9	0.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.8	9.9	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.8	3.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.8	0.8	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.8	1.6	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.8	3.1	REACTOME DEFENSINS	Genes involved in Defensins
0.7	0.7	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.7	10.6	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.7	7.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.6	21.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.5	12.3	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.5	1.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	5.2	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.3	2.4	REACTOME METABOLISM OF PROTEINS	Genes involved in Metabolism of proteins
0.3	4.2	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.3	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.3	3.0	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.1	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.5	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	1.8	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events

Results for Tal1

Z-value: 43.90

Motif logo

Transcription factors associated with Tal1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tal1 motif across conditions

Conditions sorted by the z-value of the Tal1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tal1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: