Project
ENCODE: ATAC-seq of different tissues during embryonic development
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Results for Tfap2b

Z-value: 1.26

Motif logo

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Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
Tfap2b
ENSMUSG00000025927.7 transcription factor AP-2 beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_19226762_19226913Tfap2b129580.1865240.104.6e-01Click!
chr1_19217099_19217250Tfap2b32950.253303-0.047.7e-01Click!
chr1_19209073_19209255Tfap2b2040.944914-0.038.3e-01Click!
chr1_19217371_19217862Tfap2b37370.240551-0.028.8e-01Click!
chr1_19205838_19205989Tfap2b30010.265345-0.019.3e-01Click!

Activity of the Tfap2b motif across conditions

Conditions sorted by the z-value of the Tfap2b motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_3117365_3118622 18.50 Vmn1r238
 vomeronasal 1 receptor, 238
 5419
 0.17
chr18_3116815_3117174 9.28 Vmn1r238
 vomeronasal 1 receptor, 238
 6418
 0.16
chr18_20621651_20622570 7.89 Gm16090
 predicted gene 16090
 43150
 0.11
chr7_12010381_12010846 6.83 Vmn1r-ps60
 vomeronasal 1 receptor, pseudogene 60
 5547
 0.07
chr18_3116148_3116568 6.68 Vmn1r238
 vomeronasal 1 receptor, 238
 7054
 0.16
chr18_20616739_20617639 6.31 Gm16090
 predicted gene 16090
 48071
 0.1
chr18_3118971_3119257 6.29 Vmn1r238
 vomeronasal 1 receptor, 238
 4298
 0.18
chr7_12012707_12013031 5.88 Vmn1r-ps60
 vomeronasal 1 receptor, pseudogene 60
 7803
 0.06
chr18_3119520_3119704 5.57 Vmn1r238
 vomeronasal 1 receptor, 238
 3800
 0.19
chr7_12012353_12012504 4.80 Vmn1r-ps60
 vomeronasal 1 receptor, pseudogene 60
 7362
 0.06
chr18_20625060_20625736 4.03 Gm16090
 predicted gene 16090
 39862
 0.12
chr18_3115836_3115987 3.31 Vmn1r238
 vomeronasal 1 receptor, 238
 7501
 0.16
chr4_3165180_3165331 3.26 Vmn1r2
 vomeronasal 1 receptor 2
 2065
 0.29
chr7_12011626_12011813 3.18 Vmn1r-ps60
 vomeronasal 1 receptor, pseudogene 60
 6653
 0.07
chr18_3115468_3115789 2.86 Vmn1r238
 vomeronasal 1 receptor, 238
 7784
 0.16
chr18_20615543_20616002 2.47 Gm16090
 predicted gene 16090
 49488
 0.1
chr18_3118775_3118949 2.44 Vmn1r238
 vomeronasal 1 receptor, 238
 4550
 0.18
chr4_3176842_3177034 2.30 Vmn1r2
 vomeronasal 1 receptor 2
 4855
 0.19
chr18_80287426_80288075 1.50 Gm37015
 predicted gene, 37015
 15930
 0.11
chr13_72833435_72833586 1.47 D730050B12Rik
 RIKEN cDNA D730050B12 gene
 16747
 0.24
chr18_20627927_20628180 1.37 Gm16090
 predicted gene 16090
 37207
 0.12
chr5_15672583_15672734 1.22 Speer4cos
 spermatogenesis associated glutamate (E)-rich protein 4C, opposite strand transcript
 8052
 0.16
chr7_102025253_102025404 1.06 Rnf121
 ring finger protein 121
 859
 0.42
chr18_20629240_20629391 1.05 Gm16090
 predicted gene 16090
 35945
 0.13
chr5_15043056_15043231 1.04 Gm17019
 predicted gene 17019
 10145
 0.25
chr7_74687595_74687746 1.01 Gm7726
 predicted gene 7726
 12186
 0.26
chr5_14949256_14949587 1.00 Speer4e
 spermatogenesis associated glutamate (E)-rich protein 4e
 10992
 0.19
chr3_53984780_53984955 0.98 Gm8109
 predicted gene 8109
 36297
 0.15
chr18_20624320_20624587 0.96 Gm16090
 predicted gene 16090
 40807
 0.12
chr5_15551399_15551801 0.94 Gm21190
 predicted gene, 21190
 22378
 0.13
chr6_120539180_120540180 0.93 Hdhd5
 haloacid dehalogenase like hydrolase domain containing 5
 8361
 0.12
chr18_20620820_20620971 0.91 Gm16090
 predicted gene 16090
 44365
 0.11
chr4_136865069_136865433 0.90 C1qb
 complement component 1, q subcomponent, beta polypeptide
 20936
 0.14
chr10_60692133_60692313 0.87 Cdh23
 cadherin 23 (otocadherin)
 4267
 0.26
chr1_57218512_57218908 0.86 BC055402
 cDNA sequence BC055402
 3717
 0.29
chr5_15608945_15609307 0.86 Gm30613
 predicted gene, 30613
 4060
 0.18
chr17_61302066_61302300 0.86 Obox6-ps1
 oocyte specific homeobox 6, pseudogene 1
 58390
 0.15
chr18_46484000_46484192 0.84 Gm24076
 predicted gene, 24076
 10072
 0.13
chr18_20623022_20623191 0.82 Gm16090
 predicted gene 16090
 42154
 0.12
chr13_54693536_54694669 0.81 Rnf44
 ring finger protein 44
 195
 0.91
chr2_109693106_109694421 0.81 Bdnf
 brain derived neurotrophic factor
 200
 0.94
chr1_194354828_194354979 0.81 4930503O07Rik
 RIKEN cDNA 4930503O07 gene
 132144
 0.05
chr18_20626775_20626931 0.80 Gm16090
 predicted gene 16090
 38407
 0.12
chr18_20626425_20626742 0.79 Gm16090
 predicted gene 16090
 38677
 0.12
chr5_14988977_14989543 0.78 Gm10354
 predicted gene 10354
 10325
 0.21
chr6_107713625_107713778 0.77 4933431M02Rik
 RIKEN cDNA 4933431M02 gene
 85927
 0.09
chr6_75281622_75281787 0.76 Gm6210
 predicted gene 6210
 16355
 0.25
chr18_20622786_20622961 0.73 Gm16090
 predicted gene 16090
 42387
 0.11
chr9_10269175_10269351 0.73 Gm24496
 predicted gene, 24496
 21324
 0.22
chr17_79605921_79606072 0.72 Rmdn2
 regulator of microtubule dynamics 2
 5867
 0.28
chr2_156666341_156666675 0.71 Gm14172
 predicted gene 14172
 33040
 0.1
chr2_74682809_74683583 0.71 Gm28309
 predicted gene 28309
 250
 0.69
chr1_21960934_21962001 0.70 Kcnq5
 potassium voltage-gated channel, subfamily Q, member 5
 114
 0.98
chr1_138837789_138838010 0.70 Lhx9
 LIM homeobox protein 9
 4240
 0.17
chr2_59562684_59563070 0.69 Gm13552
 predicted gene 13552
 1807
 0.42
chr7_67372280_67373557 0.68 Mef2a
 myocyte enhancer factor 2A
 60
 0.97
chr18_20618066_20618220 0.67 Gm16090
 predicted gene 16090
 47117
 0.11
chr19_43616167_43616368 0.66 Nkx2-3
 NK2 homeobox 3
 3942
 0.13
chr2_126555283_126555434 0.65 Slc27a2
 solute carrier family 27 (fatty acid transporter), member 2
 770
 0.66
chr9_8900765_8902148 0.64 Pgr
 progesterone receptor
 988
 0.68
chr17_25609260_25609765 0.63 Lmf1
 lipase maturation factor 1
 30192
 0.07
chr14_122474708_122475243 0.63 2610035F20Rik
 RIKEN cDNA 2610035F20 gene
 224
 0.69
chr15_27814807_27814975 0.62 Trio
 triple functional domain (PTPRF interacting)
 8892
 0.22
chr2_32317120_32318698 0.62 Gm23363
 predicted gene, 23363
 356
 0.45
chr2_106692893_106694599 0.61 Mpped2
 metallophosphoesterase domain containing 2
 477
 0.85
chr7_68311669_68311820 0.61 4930405G09Rik
 RIKEN cDNA 4930405G09 gene
 5288
 0.14
chr18_20620535_20620686 0.61 Gm16090
 predicted gene 16090
 44650
 0.11
chr1_82634564_82634787 0.60 n-R5s213
 nuclear encoded rRNA 5S 213
 338
 0.87
chr18_20626992_20627160 0.60 Gm16090
 predicted gene 16090
 38184
 0.12
chr7_49560224_49560375 0.59 Nav2
 neuron navigator 2
 6407
 0.28
chr10_121475538_121476618 0.58 Rassf3
 Ras association (RalGDS/AF-6) domain family member 3
 269
 0.86
chr17_35425252_35425979 0.57 H2-Q6
 histocompatibility 2, Q region locus 6
 738
 0.41
chr4_147349805_147350010 0.57 Zfp978
 zinc finger protein 978
 11396
 0.13
chr10_126978694_126979699 0.57 Ctdsp2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
 167
 0.89
chr5_122092798_122093169 0.57 Myl2
 myosin, light polypeptide 2, regulatory, cardiac, slow
 7968
 0.14
chr17_47878037_47879117 0.56 Foxp4
 forkhead box P4
 376
 0.81
chr3_132949340_132950694 0.56 Npnt
 nephronectin
 26
 0.97
chr8_66486037_66486995 0.56 Tma16
 translation machinery associated 16
 3
 0.97
chr12_112125881_112126258 0.55 Mir203
 microRNA 203
 4811
 0.13
chr10_96460717_96460875 0.55 Gm8601
 predicted gene 8601
 15683
 0.19
chr3_122729485_122730960 0.55 Pde5a
 phosphodiesterase 5A, cGMP-specific
 0
 0.98
chr8_97633073_97633363 0.54 Gm7191
 predicted gene 7191
 66626
 0.14
chr2_44920846_44920997 0.54 Gtdc1
 glycosyltransferase-like domain containing 1
 6228
 0.29
chr8_122610722_122612153 0.54 Galns
 galactosamine (N-acetyl)-6-sulfate sulfatase
 26
 0.7
chr8_15027100_15028701 0.53 Gm37844
 predicted gene, 37844
 522
 0.44
chr9_23487032_23487234 0.53 Bmper
 BMP-binding endothelial regulator
 113201
 0.07
chr18_20627726_20627877 0.53 Gm16090
 predicted gene 16090
 37459
 0.12
chr9_91378183_91378872 0.53 Zic4
 zinc finger protein of the cerebellum 4
 115
 0.94
chr17_28553454_28553746 0.53 Clpsl2
 colipase-like 2
 4189
 0.09
chr3_130839108_130839269 0.53 Gm5982
 predicted gene 5982
 7785
 0.12
chr6_125157136_125157596 0.52 Iffo1
 intermediate filament family orphan 1
 4018
 0.08
chr9_59539422_59540161 0.51 Tmem202
 transmembrane protein 202
 56
 0.75
chr10_107271547_107272835 0.50 Lin7a
 lin-7 homolog A (C. elegans)
 203
 0.96
chr11_21997009_21997356 0.50 Otx1
 orthodenticle homeobox 1
 4433
 0.28
chr19_26977887_26978038 0.49 Gm50121
 predicted gene, 50121
 48019
 0.16
chr12_29871996_29872873 0.49 Myt1l
 myelin transcription factor 1-like
 20886
 0.24
chr5_125389083_125389845 0.49 Gm10382
 predicted gene 10382
 142
 0.67
chr2_179292721_179292959 0.49 Gm14293
 predicted gene 14293
 52350
 0.14
chr17_85628600_85628757 0.49 Six3
 sine oculis-related homeobox 3
 7647
 0.15
chr5_43032065_43032228 0.48 Gm43700
 predicted gene 43700
 6090
 0.19
chr15_76133386_76133744 0.47 BC024139
 cDNA sequence BC024139
 6969
 0.09
chr15_102257553_102258012 0.47 Rarg
 retinoic acid receptor, gamma
 265
 0.82
chr8_46740254_46741749 0.47 Irf2
 interferon regulatory factor 2
 735
 0.53
chr1_189343290_189344052 0.47 Kcnk2
 potassium channel, subfamily K, member 2
 36
 0.76
chr6_114968557_114970098 0.47 Vgll4
 vestigial like family member 4
 147
 0.97
chr6_52245954_52246438 0.46 Hoxa11os
 homeobox A11, opposite strand
 25
 0.82
chr16_90533266_90533417 0.46 Gm36001
 predicted gene, 36001
 17268
 0.15
chr12_108906675_108906826 0.46 Wdr25
 WD repeat domain 25
 5982
 0.13
chr16_17497025_17497176 0.46 Aifm3
 apoptosis-inducing factor, mitochondrion-associated 3
 2599
 0.15
chr13_110230204_110230355 0.45 Rab3c
 RAB3C, member RAS oncogene family
 49871
 0.16
chr7_57508956_57510254 0.45 Gabra5
 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
 234
 0.95
chr5_36100815_36100966 0.45 Psapl1
 prosaposin-like 1
 103131
 0.07
chr10_107437084_107437235 0.45 Gm38117
 predicted gene, 38117
 200
 0.95
chr17_17827653_17828872 0.45 Spaca6
 sperm acrosome associated 6
 938
 0.31
chr5_123027620_123027774 0.44 Gm43412
 predicted gene 43412
 8303
 0.09
chr14_14345884_14346978 0.44 Il3ra
 interleukin 3 receptor, alpha chain
 1
 0.93
chr13_105256983_105257274 0.44 Rnf180
 ring finger protein 180
 13911
 0.24
chr11_5835203_5835354 0.44 Polm
 polymerase (DNA directed), mu
 1207
 0.32
chr4_10883845_10884023 0.43 2610301B20Rik
 RIKEN cDNA 2610301B20 gene
 4395
 0.16
chr16_73096919_73097070 0.43 4930500H12Rik
 RIKEN cDNA 4930500H12 gene
 1913
 0.49
chr13_41705506_41705657 0.43 Gm5082
 predicted gene 5082
 49884
 0.12
chr1_63273306_63273901 0.43 Gm24513
 predicted gene, 24513
 240
 0.49
chr4_120170416_120170874 0.43 Edn2
 endothelin 2
 9439
 0.24
chr1_18463225_18463376 0.43 Defb41
 defensin beta 41
 198162
 0.02
chr18_68711266_68711468 0.42 Mir6356
 microRNA 6356
 28033
 0.21
chr16_74182688_74182857 0.42 Gm49659
 predicted gene, 49659
 3938
 0.24
chr10_122985267_122986641 0.42 D630033A02Rik
 RIKEN cDNA D630033A02 gene
 123
 0.65
chr5_14914343_14915097 0.42 Gm9758
 predicted gene 9758
 133
 0.97
chr5_136711274_136711425 0.42 Myl10
 myosin, light chain 10, regulatory
 13519
 0.2
chr19_42764540_42764691 0.41 Hps1
 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
 739
 0.61
chr9_22767838_22767989 0.41 Gm27639
 predicted gene, 27639
 4922
 0.27
chr6_87898144_87898295 0.41 Copg1
 coatomer protein complex, subunit gamma 1
 416
 0.7
chr3_40185875_40186026 0.41 1700017G19Rik
 RIKEN cDNA 1700017G19 gene
 323824
 0.01
chr5_90988282_90988433 0.40 Epgn
 epithelial mitogen
 39107
 0.11
chr4_154709923_154710074 0.40 Actrt2
 actin-related protein T2
 42131
 0.11
chr14_36646374_36646525 0.40 Gm17940
 predicted gene, 17940
 27171
 0.2
chr6_55335921_55336550 0.39 Aqp1
 aquaporin 1
 197
 0.93
chr2_32390923_32391074 0.39 Lcn2
 lipocalin 2
 2746
 0.12
chr2_31508651_31508802 0.39 Ass1
 argininosuccinate synthetase 1
 8000
 0.18
chr10_87586828_87586979 0.38 Pah
 phenylalanine hydroxylase
 40230
 0.16
chr5_15577027_15578025 0.38 Gm21083
 predicted gene, 21083
 193
 0.93
chr13_56769978_56770289 0.38 Gm45623
 predicted gene 45623
 16306
 0.21
chr3_116969934_116970085 0.38 Palmd
 palmdelphin
 1022
 0.4
chr16_40652871_40653153 0.37 Gm27887
 predicted gene, 27887
 285075
 0.01
chr19_3392510_3392690 0.37 Tesmin
 testis expressed metallothionein like
 3221
 0.18
chr15_103334189_103334404 0.36 Zfp385a
 zinc finger protein 385A
 31
 0.95
chr1_129272928_129273957 0.36 Thsd7b
 thrombospondin, type I, domain containing 7B
 21
 0.98
chr5_114743003_114743280 0.36 Git2
 GIT ArfGAP 2
 727
 0.5
chr11_95247117_95247412 0.36 Tac4
 tachykinin 4
 14265
 0.13
chr6_118593411_118594059 0.36 Cacna1c
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 1691
 0.37
chr1_172019892_172020043 0.35 Vangl2
 VANGL planar cell polarity 2
 6744
 0.14
chr5_52604627_52604846 0.35 8030423F21Rik
 RIKEN cDNA 8030423F21 gene
 14276
 0.14
chr10_29534276_29534889 0.35 Gm48159
 predicted gene, 48159
 135
 0.94
chr3_30108418_30108578 0.35 Mecom
 MDS1 and EVI1 complex locus
 31925
 0.17
chr8_80057499_80058156 0.34 Hhip
 Hedgehog-interacting protein
 179
 0.95
chr7_62420605_62420845 0.34 Mkrn3
 makorin, ring finger protein, 3
 586
 0.68
chr5_15032326_15032654 0.34 Gm17019
 predicted gene 17019
 508
 0.84
chr12_8063506_8063657 0.33 Apob
 apolipoprotein B
 51222
 0.14
chr6_119479409_119481030 0.33 Fbxl14
 F-box and leucine-rich repeat protein 14
 551
 0.78
chr10_32889642_32890523 0.33 Nkain2
 Na+/K+ transporting ATPase interacting 2
 234
 0.95
chr2_105126173_105126893 0.33 Wt1
 Wilms tumor 1 homolog
 4
 0.5
chr16_90283526_90284553 0.33 Scaf4
 SR-related CTD-associated factor 4
 269
 0.9
chr1_194769289_194769440 0.33 Plxna2
 plexin A2
 4797
 0.2
chr11_116436453_116437309 0.33 Ubald2
 UBA-like domain containing 2
 2372
 0.17
chr1_134182287_134182438 0.33 Chil1
 chitinase-like 1
 42
 0.97
chr13_89371778_89371957 0.33 Hapln1
 hyaluronan and proteoglycan link protein 1
 167929
 0.04
chr6_99520900_99522395 0.33 Foxp1
 forkhead box P1
 485
 0.83
chr13_69261120_69261271 0.33 Gm4812
 predicted gene 4812
 84460
 0.08
chr11_115889200_115889351 0.32 Myo15b
 myosin XVB
 964
 0.35
chr5_13470497_13470849 0.32 Gm43130
 predicted gene 43130
 10355
 0.22
chr5_113492671_113492876 0.32 Wscd2
 WSC domain containing 2
 2021
 0.38
chr2_28566649_28566800 0.32 Cel
 carboxyl ester lipase
 3321
 0.12
chr14_120389109_120389704 0.32 Gm26679
 predicted gene, 26679
 421
 0.87
chr11_84879754_84880861 0.32 Myo19
 myosin XIX
 3
 0.5
chr13_119741850_119742224 0.32 Nim1k
 NIM1 serine/threonine protein kinase
 3643
 0.15
chr5_119743739_119744135 0.31 Tbx3os2
 T-box 3, opposite strand 2
 52719
 0.1
chr11_74896307_74898160 0.31 Sgsm2
 small G protein signaling modulator 2
 173
 0.84
chr9_61549545_61549892 0.31 Gm34424
 predicted gene, 34424
 16303
 0.23
chr12_32995168_32995399 0.31 Gm24922
 predicted gene, 24922
 4727
 0.16
chr3_135581620_135581778 0.31 Nfkb1
 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
 12742
 0.16
chr8_105604817_105605984 0.31 Ripor1
 RHO family interacting cell polarization regulator 1
 145
 0.9
chr4_110152119_110152431 0.31 Elavl4
 ELAV like RNA binding protein 4
 70873
 0.12
chr2_131040943_131041967 0.31 Gfra4
 glial cell line derived neurotrophic factor family receptor alpha 4
 2
 0.94
chr7_25729452_25729603 0.31 Ccdc97
 coiled-coil domain containing 97
 10439
 0.09
chr15_96474728_96474879 0.31 Scaf11
 SR-related CTD-associated factor 11
 13960
 0.19
chr1_135771295_135771469 0.31 Phlda3
 pleckstrin homology like domain, family A, member 3
 4248
 0.17
chr1_190042210_190042373 0.30 Smyd2
 SET and MYND domain containing 2
 119928
 0.05
chr9_56657298_56657483 0.30 Lingo1
 leucine rich repeat and Ig domain containing 1
 9730
 0.21
chr10_94943541_94945198 0.30 Plxnc1
 plexin C1
 466
 0.84
chr4_147397309_147397460 0.30 Gm8178
 predicted gene 8178
 18455
 0.13
chr8_84945228_84946066 0.30 Rtbdn
 retbindin
 1344
 0.18
chr5_14978282_14978636 0.29 Gm10354
 predicted gene 10354
 476
 0.83
chr1_141137215_141137503 0.29 Gm4845
 predicted gene 4845
 119798
 0.06
chr5_137580251_137580513 0.29 Tfr2
 transferrin receptor 2
 1489
 0.17
chr11_115831581_115831861 0.29 Llgl2
 LLGL2 scribble cell polarity complex component
 247
 0.85
chr4_136144287_136145200 0.29 Id3
 inhibitor of DNA binding 3
 231
 0.9
chr15_69107943_69108094 0.29 4930573C08Rik
 RIKEN cDNA 4930573C08 gene
 126981
 0.05
chr8_69121372_69122097 0.29 Atp6v1b2
 ATPase, H+ transporting, lysosomal V1 subunit B2
 18606
 0.14
chr5_137510563_137511218 0.29 Gm8066
 predicted gene 8066
 637
 0.45
chr6_114131157_114131308 0.29 Slc6a11
 solute carrier family 6 (neurotransmitter transporter, GABA), member 11
 9
 0.98

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 2.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412)
0.2 0.5 GO:0097195 pilomotor reflex(GO:0097195)
0.2 0.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 0.5 GO:0071288 cellular response to mercury ion(GO:0071288)
0.2 0.5 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.4 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.2 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.1 0.3 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.2 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.2 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.1 0.2 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.5 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.0 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.4 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 1.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0043096 purine nucleobase salvage(GO:0043096)
0.0 0.0 GO:0046514 ceramide catabolic process(GO:0046514)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.0 GO:0046103 inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.0 GO:0072034 renal vesicle induction(GO:0072034) metanephric nephron tubule formation(GO:0072289)
0.0 0.1 GO:0097466 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0051136 regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.0 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0098597 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597) learned vocalization behavior or vocal learning(GO:0098598)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.0 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.1 GO:0070627 ferrous iron import(GO:0070627)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.0 GO:1903935 response to sodium arsenite(GO:1903935)
0.0 0.1 GO:0045990 carbon catabolite regulation of transcription(GO:0045990)
0.0 0.1 GO:0003163 sinoatrial node development(GO:0003163)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.0 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.1 GO:1903887 motile primary cilium assembly(GO:1903887)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.1 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0036065 fucosylation(GO:0036065)
0.0 0.0 GO:1902805 positive regulation of synaptic vesicle transport(GO:1902805)
0.0 0.1 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.4 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.0 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0010224 response to UV-B(GO:0010224)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.1 GO:1901160 serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0 0.0 GO:1902988 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0044860 protein localization to plasma membrane raft(GO:0044860)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005914 spot adherens junction(GO:0005914)
0.2 3.3 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.9 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:0097452 GAIT complex(GO:0097452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.9 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.6 GO:0030553 cGMP binding(GO:0030553)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0046977 TAP binding(GO:0046977)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:1990190 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 2.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.0 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0034547 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0005550 pheromone binding(GO:0005550)
0.0 0.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 ST ADRENERGIC Adrenergic Pathway
0.0 0.1 PID ATM PATHWAY ATM pathway
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.0 REACTOME G1 S TRANSITION Genes involved in G1/S Transition
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins