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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Tfap2e

Z-value: 0.97

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Transcription factors associated with Tfap2e

Gene Symbol	Gene ID	Gene Info
Tfap2e Ensembl NCBI MGI UniProt	ENSMUSG00000042477.7	transcription factor AP-2, epsilon

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_126707073_126707478	Tfap2e	28965	0.105040	0.45	5.0e-04	Click!
chr4_126741576_126741746	Tfap2e	5421	0.143386	-0.19	1.6e-01	Click!

Activity of the Tfap2e motif across conditions

Conditions sorted by the z-value of the Tfap2e motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_162221037_162221188	3.61	Dnm3os	dynamin 3, opposite strand	1244	0.37
chr7_57138203_57138354	2.48	Gm18642	predicted gene, 18642	112197	0.07
chr9_86762802_86762953	2.45	Prss35	protease, serine 35	19228	0.12
chr10_121873065_121873455	2.43	Gm48804	predicted gene, 48804	41202	0.15
chr4_149914094_149914250	2.42	Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	4356	0.18
chr18_79106086_79106237	2.30	Setbp1	SET binding protein 1	3230	0.37
chr10_3864271_3864422	2.27	Gm16149	predicted gene 16149	5261	0.21
chr15_10952196_10952401	2.22	C1qtnf3	C1q and tumor necrosis factor related protein 3	34	0.97
chr12_27187507_27187842	2.22	Gm9866	predicted gene 9866	27041	0.24
chr3_121577007_121577572	2.18	Slc44a3	solute carrier family 44, member 3	44885	0.11
chr11_11828263_11828605	2.09	Ddc	dopa decarboxylase	5513	0.2
chr14_31125276_31125695	2.01	Smim4	small integral membrane protein 4	3353	0.14
chr13_75541571_75541722	1.98	Gm3926	predicted gene 3926	17298	0.15
chr9_83305077_83305228	1.87	Gm46123	predicted gene, 46123	41007	0.13
chr12_33955975_33956126	1.86	Twist1	twist basic helix-loop-helix transcription factor 1	1621	0.41
chr5_74214849_74215000	1.82	Scfd2	Sec1 family domain containing 2	10560	0.15
chr5_96373518_96374929	1.80	Fras1	Fraser extracellular matrix complex subunit 1	17	0.99
chr6_22202002_22202201	1.78	Gm42573	predicted gene 42573	43833	0.16
chr8_81260178_81260375	1.72	Gm45539	predicted gene 45539	34787	0.16
chr13_32611765_32612081	1.67	AL645799.1	novel transcript	2093	0.39
chr11_35407713_35407933	1.62	Gm12122	predicted gene 12122	57754	0.14
chr9_41918970_41919408	1.60	Gm40513	predicted gene, 40513	28585	0.14
chr14_25044962_25045146	1.59	Gm47907	predicted gene, 47907	13957	0.17
chr5_136702241_136702613	1.59	Myl10	myosin, light chain 10, regulatory	4597	0.24
chr13_18575665_18575816	1.54	Gm48829	predicted gene, 48829	69609	0.12
chr2_21267205_21267356	1.53	Gm13378	predicted gene 13378	23175	0.18
chr6_30169255_30169434	1.49	Mir96	microRNA 96	207	0.68
chr4_117316934_117317085	1.46	Rnf220	ring finger protein 220	16981	0.13
chr8_102983403_102983579	1.45	Gm8730	predicted pseudogene 8730	117693	0.06
chr5_103029055_103029485	1.45	Mapk10	mitogen-activated protein kinase 10	2275	0.37
chr12_118529751_118529986	1.43	D230030E09Rik	Riken cDNA D230030E09 gene	325	0.91
chr4_9981765_9981916	1.42	Gm11835	predicted gene 11835	22486	0.19
chr2_74712059_74712650	1.40	Hoxd3os1	homeobox D3, opposite strand 1	172	0.58
chr13_111845607_111845774	1.39	Gm15325	predicted gene 15325	6932	0.14
chr17_79145323_79145513	1.34	Gm49869	predicted gene, 49869	41674	0.15
chr2_77816275_77817277	1.32	Zfp385b	zinc finger protein 385B	40	0.98
chr16_30397261_30397963	1.31	Atp13a3	ATPase type 13A3	8363	0.21
chr17_49816116_49816498	1.31	Gm16555	predicted gene 16555	5518	0.26
chr10_64641714_64641867	1.28	Gm23854	predicted gene, 23854	337046	0.01
chr17_17408850_17409001	1.28	Gm26873	predicted gene, 26873	3068	0.2
chr13_117235503_117236043	1.27	Emb	embigin	7747	0.21
chr10_52703895_52704096	1.26	Gm47624	predicted gene, 47624	10157	0.19
chr6_147972662_147972813	1.24	Far2	fatty acyl CoA reductase 2	74522	0.09
chr4_147343391_147343923	1.24	Zfp988	zinc finger protein 988	11250	0.13
chr9_62721958_62722126	1.19	Itga11	integrin alpha 11	44182	0.14
chr5_139535356_139536005	1.19	Uncx	UNC homeobox	7814	0.16
chr11_87577737_87577901	1.16	Septin4	septin 4	582	0.66
chr6_36221425_36221576	1.15	Gm43443	predicted gene 43443	32401	0.2
chr2_174760490_174760659	1.15	Edn3	endothelin 3	45	0.98
chr16_87341326_87341477	1.14	N6amt1	N-6 adenine-specific DNA methyltransferase 1 (putative)	12784	0.22
chr13_84515013_84515539	1.13	Gm26927	predicted gene, 26927	175163	0.03
chr3_24630114_24630286	1.13	Gm24704	predicted gene, 24704	68126	0.14
chr18_57981702_57981894	1.13	Fbn2	fibrillin 2	45082	0.17
chr1_83878665_83878827	1.10	4933436I20Rik	RIKEN cDNA 4933436I20 gene	32825	0.18
chr18_77564045_77564233	1.08	Rnf165	ring finger protein 165	470	0.85
chr7_108797287_108797500	1.08	Gm45232	predicted gene 45232	2390	0.19
chr14_55716843_55717094	1.08	Rabggta	Rab geranylgeranyl transferase, a subunit	2178	0.11
chr4_64047197_64047444	1.06	Tnc	tenascin C	305	0.92
chr10_61866052_61866442	1.05	Col13a1	collagen, type XIII, alpha 1	166	0.96
chr9_122285507_122285868	1.05	Ano10	anoctamin 10	8659	0.13
chr7_19118025_19118835	1.05	Gm4969	predicted gene 4969	62	0.92
chr5_115007642_115007807	1.03	Sppl3	signal peptide peptidase 3	3413	0.12
chr5_49880535_49880690	1.03	Gm7988	predicted gene 7988	21690	0.22
chr8_97233084_97233251	1.01	Gm25160	predicted gene, 25160	10633	0.17
chr2_119196480_119196631	0.99	Gm14138	predicted gene 14138	9038	0.09
chr4_114767178_114767329	0.98	Gm12830	predicted gene 12830	54469	0.11
chr6_16317881_16318284	0.98	Gm3148	predicted gene 3148	80455	0.1
chr19_56177181_56177795	0.98	Gm31912	predicted gene, 31912	71178	0.1
chr8_121919864_121920015	0.98	Car5a	carbonic anhydrase 5a, mitochondrial	7535	0.1
chr11_4308611_4309015	0.96	Gm24803	predicted gene, 24803	15442	0.12
chr13_89741226_89741547	0.96	Vcan	versican	858	0.59
chr11_7409190_7409341	0.95	Gm11986	predicted gene 11986	118891	0.06
chr1_21461124_21461330	0.95	Gm36949	predicted gene, 36949	4210	0.2
chr5_53266273_53266449	0.94	Smim20	small integral membrane protein 20	722	0.67
chr7_68919196_68919350	0.94	Gm34664	predicted gene, 34664	3257	0.29
chr17_79715582_79716163	0.93	Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	811	0.6
chr2_64325556_64325707	0.93	Gm13575	predicted gene 13575	68229	0.14
chr3_122518107_122518786	0.93	Bcar3	breast cancer anti-estrogen resistance 3	6200	0.14
chr19_56419505_56419787	0.92	Casp7	caspase 7	6039	0.19
chr12_31295582_31295782	0.91	Lamb1	laminin B1	17507	0.13
chr7_82383261_82383448	0.91	Adamtsl3	ADAMTS-like 3	25120	0.19
chr18_60647827_60648302	0.89	Synpo	synaptopodin	208	0.94
chr3_50678326_50678497	0.88	Gm37461	predicted gene, 37461	4990	0.24
chr9_107735696_107736098	0.88	Rbm5	RNA binding motif protein 5	8337	0.1
chrX_121232473_121232696	0.87	Gm5394	predicted gene 5394	54602	0.14
chr1_12510492_12510833	0.87	Gm2383	predicted gene 2383	54915	0.14
chr9_60940484_60940719	0.87	Gm47923	predicted gene, 47923	21378	0.18
chr3_55587897_55588397	0.87	Gm43549	predicted gene 43549	5417	0.18
chr1_82766615_82767003	0.87	Tm4sf20	transmembrane 4 L six family member 20	1652	0.2
chr18_23877666_23877819	0.86	Gm23207	predicted gene, 23207	60371	0.08
chr16_10192770_10193265	0.85	Atf7ip2	activating transcription factor 7 interacting protein 2	70	0.97
chr11_78168592_78169043	0.85	Nek8	NIMA (never in mitosis gene a)-related expressed kinase 8	784	0.33
chr1_91313342_91313536	0.85	Gm17090	predicted gene 17090	7662	0.11
chr3_99248515_99248723	0.85	Tbx15	T-box 15	5141	0.17
chr3_83570441_83570612	0.84	1700028M03Rik	RIKEN cDNA 1700028M03 gene	3596	0.33
chr1_153096424_153096599	0.84	Nmnat2	nicotinamide nucleotide adenylyltransferase 2	3031	0.24
chr2_27389618_27390214	0.84	Gm24049	predicted gene, 24049	11936	0.16
chr18_74539338_74539489	0.83	1700120E14Rik	RIKEN cDNA 1700120E14 gene	8289	0.25
chr18_77564959_77566098	0.82	Rnf165	ring finger protein 165	367	0.89
chr12_100061936_100062087	0.82	9530050K03Rik	RIKEN cDNA 9530050K03 gene	18806	0.14
chr9_69469113_69469304	0.82	Anxa2	annexin A2	9257	0.12
chr12_10179432_10179754	0.81	Gm48791	predicted gene, 48791	2450	0.31
chr6_108425133_108425318	0.81	Itpr1	inositol 1,4,5-trisphosphate receptor 1	7348	0.23
chr17_25556611_25556991	0.81	Gm50026	predicted gene, 50026	4412	0.09
chr1_118902149_118902552	0.80	Mir6346	microRNA 6346	51870	0.14
chr1_171251904_171252066	0.80	Adamts4	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4	131	0.81
chr9_106464770_106466154	0.79	Gpr62	G protein-coupled receptor 62	476	0.6
chr9_35333366_35333528	0.79	Gm33838	predicted gene, 33838	25848	0.11
chr2_115456492_115456652	0.79	3110099E03Rik	RIKEN cDNA 3110099E03 gene	55629	0.14
chr2_145674795_145675792	0.78	Rin2	Ras and Rab interactor 2	74	0.98
chr1_151890040_151890576	0.78	Gm28610	predicted gene 28610	14889	0.19
chr13_67779600_67780238	0.78	Zfp493	zinc finger protein 493	165	0.9
chr17_29838078_29838269	0.77	Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	1737	0.33
chr1_15892356_15892948	0.77	Sbspon	somatomedin B and thrombospondin, type 1 domain containing	70	0.98
chr11_70200228_70200379	0.76	Slc16a11	solute carrier family 16 (monocarboxylic acid transporters), member 11	12449	0.07
chr4_75855797_75855974	0.76	Gm11256	predicted gene 11256	1367	0.56
chr17_14234882_14235311	0.76	Gm34567	predicted gene, 34567	14755	0.16
chr9_103006515_103006803	0.75	Slco2a1	solute carrier organic anion transporter family, member 2a1	1343	0.37
chr6_22288043_22288221	0.75	Wnt16	wingless-type MMTV integration site family, member 16	95	0.98
chr1_192785556_192785974	0.75	Hhat	hedgehog acyltransferase	14542	0.15
chr7_109010582_109011352	0.75	Tub	tubby bipartite transcription factor	142	0.95
chr1_18416397_18416721	0.75	Defb41	defensin beta 41	151421	0.04
chr5_110486794_110486983	0.75	Gm32996	predicted gene, 32996	4687	0.16
chr4_151139945_151140096	0.75	Camta1	calmodulin binding transcription activator 1	436	0.86
chr7_45682739_45683092	0.75	Ntn5	netrin 5	1107	0.22
chr14_100619435_100619663	0.74	Gm49238	predicted gene, 49238	36212	0.16
chr8_126538413_126539616	0.74	Gm26759	predicted gene, 26759	27956	0.17
chr2_34982877_34983327	0.74	Hc	hemolytic complement	10234	0.12
chr10_39654004_39654276	0.74	Traf3ip2	TRAF3 interacting protein 2	3585	0.15
chr2_80447315_80447774	0.74	Frzb	frizzled-related protein	81	0.97
chr5_47982936_47984535	0.73	Slit2	slit guidance ligand 2	558	0.73
chr6_127708290_127708558	0.73	Gm42739	predicted gene 42739	55324	0.08
chr12_112335212_112335363	0.73	Gm38123	predicted gene, 38123	14780	0.19
chr12_13209008_13209159	0.73	Ddx1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	20296	0.16
chr1_85114233_85115011	0.72	Gm16038	predicted gene 16038	697	0.48
chr16_18683704_18683871	0.72	Rps2-ps7	ribosomal protein S2, pseudogene 7	1571	0.34
chr3_137977052_137977203	0.72	Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	4403	0.15
chr2_172485177_172485328	0.72	Fam209	family with sequence similarity 209	12732	0.13
chr7_89856490_89856666	0.71	Me3	malic enzyme 3, NADP(+)-dependent, mitochondrial	27296	0.13
chr7_139797631_139797782	0.71	Mir6401	microRNA 6401	18688	0.13
chr8_125368418_125368617	0.71	Sipa1l2	signal-induced proliferation-associated 1 like 2	124193	0.05
chr15_77036745_77036969	0.71	Apol6	apolipoprotein L 6	7872	0.11
chr8_87237253_87237404	0.71	Gm27169	predicted gene 27169	34302	0.15
chr8_88451671_88451822	0.71	Gm45497	predicted gene 45497	60625	0.11
chr17_85687855_85689066	0.70	Six2	sine oculis-related homeobox 2	186	0.94
chr2_101592687_101592869	0.70	B230118H07Rik	RIKEN cDNA B230118H07 gene	7844	0.19
chr3_67884413_67884564	0.70	Iqcj	IQ motif containing J	7732	0.23
chr18_90094586_90094765	0.68	Gm6173	predicted gene 6173	75596	0.11
chr1_52293564_52293968	0.68	Gm5975	predicted gene 5975	4671	0.25
chr19_16841485_16841798	0.68	Gm32341	predicted gene, 32341	29451	0.16
chr1_190979223_190979743	0.68	Vash2	vasohibin 2	187	0.9
chr4_154781486_154781696	0.67	Ttc34	tetratricopeptide repeat domain 34	55868	0.1
chr16_44687184_44688343	0.67	Nepro	nucleolus and neural progenitor protein	36538	0.14
chr2_94729855_94730128	0.66	Gm13793	predicted gene 13793	747	0.75
chr5_45278590_45278909	0.66	Gm43303	predicted gene 43303	26820	0.18
chr10_57040297_57040501	0.66	Gm36827	predicted gene, 36827	58167	0.13
chr5_104109154_104109490	0.66	Gm26703	predicted gene, 26703	31	0.96
chr4_142674754_142674905	0.66	Gm37624	predicted gene, 37624	115979	0.06
chr7_31076595_31076776	0.66	Fxyd3	FXYD domain-containing ion transport regulator 3	16	0.95
chr1_118595417_118595792	0.65	Clasp1	CLIP associating protein 1	9123	0.17
chr2_26314271_26314532	0.65	Gpsm1	G-protein signalling modulator 1 (AGS3-like, C. elegans)	1114	0.34
chr11_9191272_9191452	0.65	Abca13	ATP-binding cassette, sub-family A (ABC1), member 13	580	0.8
chr18_20188319_20188643	0.65	Dsg1c	desmoglein 1 gamma	58859	0.12
chr3_133877305_133877715	0.65	Gm30484	predicted gene, 30484	58992	0.13
chr6_134128205_134128356	0.65	Gm43984	predicted gene, 43984	43679	0.12
chr10_5922652_5922867	0.65	Rgs17	regulator of G-protein signaling 17	359	0.92
chrX_133655989_133656226	0.64	Pcdh19	protocadherin 19	28884	0.24
chr10_78594275_78594426	0.64	Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	2386	0.12
chr2_167206316_167206467	0.64	Ptgis	prostaglandin I2 (prostacyclin) synthase	2025	0.23
chr14_52328141_52328337	0.64	Sall2	spalt like transcription factor 2	523	0.59
chr2_132989928_132990079	0.64	Gm14101	predicted gene 14101	8835	0.16
chr16_57383629_57383811	0.64	Filip1l	filamin A interacting protein 1-like	30443	0.15
chrX_143664513_143664895	0.63	Pak3	p21 (RAC1) activated kinase 3	125	0.98
chr3_97312015_97312394	0.63	Bcl9	B cell CLL/lymphoma 9	14287	0.18
chr1_85243802_85244548	0.63	C130026I21Rik	RIKEN cDNA C130026I21 gene	2222	0.19
chr12_13077810_13077961	0.62	Gm48209	predicted gene, 48209	23156	0.14
chr18_80633674_80633825	0.62	Nfatc1	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	24774	0.16
chr4_118037599_118037750	0.62	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	5792	0.2
chr14_102981698_102983184	0.62	Mir5130	microRNA 5130	191	0.49
chr8_23314400_23314551	0.61	Gm24335	predicted gene, 24335	24311	0.15
chrX_169881520_169881671	0.61	Mid1	midline 1	1931	0.42
chr2_25240744_25241709	0.61	Cysrt1	cysteine rich tail 1	1226	0.15
chr9_8133668_8134355	0.61	Cep126	centrosomal protein 126	283	0.9
chr2_75000578_75000751	0.60	n-R5s198	nuclear encoded rRNA 5S 198	65150	0.09
chr19_47328251_47328788	0.60	Sh3pxd2a	SH3 and PX domains 2A	13768	0.18
chr5_35609331_35609878	0.60	Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	495	0.75
chr19_45796139_45796299	0.60	Kcnip2	Kv channel-interacting protein 2	515	0.73
chr14_34936664_34936815	0.60	Mir346	microRNA 346	42130	0.18
chr9_113479906_113480057	0.60	AU023762	expressed sequence AU023762	28374	0.16
chr11_119514915_119515560	0.60	Endov	endonuclease V	13259	0.13
chr5_129430055_129430253	0.60	Gm43001	predicted gene 43001	66034	0.09
chr4_148918903_148919115	0.60	Gm15969	predicted gene 15969	4685	0.18
chr4_95075494_95075799	0.60	Junos	jun proto-oncogene, opposite strand	23	0.96
chr13_15464892_15465326	0.60	Gli3	GLI-Kruppel family member GLI3	1129	0.38
chr12_107750672_107750856	0.59	4930465M20Rik	RIKEN cDNA 4930465M20 gene	15268	0.23
chr9_108988525_108988676	0.59	Ucn2	urocortin 2	2590	0.12
chr8_121468473_121468817	0.59	Gm26784	predicted gene, 26784	33665	0.12
chr4_132469772_132470080	0.59	Med18	mediator complex subunit 18	6005	0.11
chr12_85638862_85639281	0.59	Gm33312	predicted gene, 33312	23371	0.13
chr2_32317120_32318698	0.59	Gm23363	predicted gene, 23363	356	0.45

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2e

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.1	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3	1.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.3	0.8	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2	0.7	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.2	1.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.2	0.7	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.2	0.7	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.2	0.8	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.2	0.6	GO:0002930	trabecular meshwork development(GO:0002930)
0.2	0.4	GO:0072198	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2	0.5	GO:0089700	protein kinase D signaling(GO:0089700)
0.2	0.5	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.2	0.5	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.4	GO:0021558	trochlear nerve development(GO:0021558)
0.1	0.4	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.4	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.9	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	0.5	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.3	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1	0.8	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.1	0.1	GO:0072077	renal vesicle morphogenesis(GO:0072077)
0.1	0.4	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.4	GO:0015888	thiamine transport(GO:0015888)
0.1	1.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.3	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.1	0.5	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.2	GO:0038091	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	1.8	GO:0003338	metanephros morphogenesis(GO:0003338)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.5	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	1.3	GO:0046549	retinal cone cell development(GO:0046549)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670)
0.1	0.3	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1	0.3	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	1.8	GO:0060384	innervation(GO:0060384)
0.1	0.2	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1	0.4	GO:0033762	response to glucagon(GO:0033762)
0.1	0.2	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1	0.4	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.1	0.1	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	0.2	GO:0060921	sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.1	0.2	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1	0.7	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.1	0.1	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.1	0.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	0.4	GO:1904424	regulation of GTP binding(GO:1904424)
0.1	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.1	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.1	0.1	GO:0097503	sialylation(GO:0097503)
0.1	0.4	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.1	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.1	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.2	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.1	0.2	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.1	0.3	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.1	0.2	GO:0045404	positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1	0.4	GO:0035330	regulation of hippo signaling(GO:0035330)
0.1	0.4	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.1	0.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.5	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.2	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.1	0.2	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.3	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.3	GO:0034651	cortisol biosynthetic process(GO:0034651)
0.0	0.1	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.5	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.5	GO:0033700	phospholipid efflux(GO:0033700)
0.0	0.1	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0	0.2	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.2	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.2	GO:0035907	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.1	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.2	GO:0033504	floor plate development(GO:0033504)
0.0	0.9	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0030421	defecation(GO:0030421)
0.0	0.1	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.0	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0072240	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:1902805	positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:0021550	medulla oblongata development(GO:0021550)
0.0	0.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.3	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.1	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0	0.2	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.5	GO:0016082	synaptic vesicle priming(GO:0016082)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.4	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.4	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.3	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0042161	lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.2	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.4	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.1	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.7	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.7	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0086029	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0	0.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.0	0.1	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.4	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.0	GO:0002086	diaphragm contraction(GO:0002086)
0.0	0.1	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:1901628	positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.2	GO:0021756	striatum development(GO:0021756)
0.0	0.2	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.0	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.3	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.2	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.3	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.0	GO:1904180	negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.0	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.1	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.7	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.3	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	0.1	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.1	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.1	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.0	GO:2000668	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.2	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.4	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.2	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0043586	tongue development(GO:0043586)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.6	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.0	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
0.0	0.0	GO:0003166	bundle of His development(GO:0003166)
0.0	0.1	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0	0.0	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0097152	mesenchymal cell apoptotic process(GO:0097152)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.7	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.0	0.2	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.0	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0	0.0	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.0	GO:0002248	wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0072008	glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0	0.0	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.4	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.0	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.0	GO:0070949	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.3	GO:0047496	vesicle transport along microtubule(GO:0047496)
0.0	0.0	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.0	GO:0009158	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.0	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.2	GO:0035094	response to nicotine(GO:0035094)
0.0	0.0	GO:0032730	positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.4	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.3	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.2	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.0	0.0	GO:0033133	positive regulation of glucokinase activity(GO:0033133)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0070552	BRISC complex(GO:0070552)
0.1	0.3	GO:1990812	growth cone filopodium(GO:1990812)
0.1	0.4	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.5	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.3	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	0.5	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	1.3	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0044308	axonal spine(GO:0044308)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.3	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	3.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.5	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.6	GO:0008305	integrin complex(GO:0008305)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.3	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.4	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.3	GO:0005604	basement membrane(GO:0005604)
0.0	3.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	1.5	GO:0043204	perikaryon(GO:0043204)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.2	GO:0097546	ciliary base(GO:0097546)
0.0	0.0	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.0	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	0.7	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.2	0.5	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.1	1.0	GO:0045545	syndecan binding(GO:0045545)
0.1	0.4	GO:0045503	dynein light chain binding(GO:0045503)
0.1	0.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.4	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.6	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.5	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.2	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1	0.4	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.1	0.3	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1	0.2	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.2	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	0.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.2	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.2	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.2	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.4	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.2	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.3	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.5	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.7	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.4	GO:0044548	S100 protein binding(GO:0044548)
0.0	1.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.8	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.3	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.3	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	1.0	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	1.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.8	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.0	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.2	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.0	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0051870	methotrexate binding(GO:0051870)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.3	GO:0016504	peptidase activator activity(GO:0016504)
0.0	0.1	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.0	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0033677	DNA/RNA helicase activity(GO:0033677)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)
0.0	0.2	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.0	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	2.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	1.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	2.3	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.8	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	4.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.8	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.9	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	2.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	2.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.6	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Results for Tfap2e

Z-value: 0.97

Motif logo

Transcription factors associated with Tfap2e

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tfap2e motif across conditions

Conditions sorted by the z-value of the Tfap2e motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2e

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: