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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Trp63

Z-value: 0.99

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Transcription factors associated with Trp63

Gene Symbol	Gene ID	Gene Info
Trp63 Ensembl NCBI MGI UniProt	ENSMUSG00000022510.8	transformation related protein 63

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_25660958_25661109	Trp63	22730	0.211081	-0.49	1.7e-04	Click!
chr16_25615359_25615510	Trp63	68329	0.118399	-0.42	1.2e-03	Click!
chr16_25792750_25792908	Trp63	9087	0.263565	-0.30	2.6e-02	Click!
chr16_25805040_25805198	Trp63	3203	0.341319	0.29	3.2e-02	Click!
chr16_25860881_25861032	Trp63	59040	0.134392	0.23	8.8e-02	Click!

Activity of the Trp63 motif across conditions

Conditions sorted by the z-value of the Trp63 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_90727394_90727734	4.45	Tom1l1	target of myb1-like 1 (chicken)	39198	0.15
chr4_153670248_153670406	4.23	Ajap1	adherens junction associated protein 1	187516	0.03
chr7_111179367_111179913	3.60	1700012D14Rik	RIKEN cDNA 1700012D14 gene	56956	0.11
chr1_130744378_130744557	2.83	Gm28857	predicted gene 28857	3140	0.12
chr11_102365077_102365683	2.83	Slc4a1	solute carrier family 4 (anion exchanger), member 1	100	0.94
chr16_90738693_90738854	2.72	Mrap	melanocortin 2 receptor accessory protein	449	0.78
chr15_102395443_102395620	2.51	Sp1	trans-acting transcription factor 1	10612	0.09
chr14_30921060_30921211	2.48	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	2414	0.17
chr15_98602185_98602446	2.44	Adcy6	adenylate cyclase 6	2416	0.14
chr8_128112942_128113479	2.36	Mir21c	microRNA 21c	165015	0.04
chr5_119811420_119811765	2.25	1700021F13Rik	RIKEN cDNA 1700021F13 gene	3723	0.21
chr2_26593817_26594312	2.24	Egfl7	EGF-like domain 7	1917	0.15
chr3_153689820_153690029	2.20	Gm22206	predicted gene, 22206	18987	0.16
chr5_123655134_123655301	2.16	Clip1	CAP-GLY domain containing linker protein 1	691	0.56
chr18_35848127_35849279	2.12	Cxxc5	CXXC finger 5	5984	0.11
chr6_17737672_17737964	2.10	St7	suppression of tumorigenicity 7	5774	0.15
chrX_96025485_96025664	2.10	Las1l	LAS1-like (S. cerevisiae)	68612	0.1
chr11_32250666_32250873	2.04	Nprl3	nitrogen permease regulator-like 3	491	0.67
chr16_90761075_90761248	2.02	Urb1	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)	11630	0.14
chr1_184644844_184645028	2.00	Gm37800	predicted gene, 37800	15463	0.15
chr7_16706509_16706668	1.99	Gm8209	predicted gene 8209	12219	0.09
chr1_165104970_165105154	1.96	4930568G15Rik	RIKEN cDNA 4930568G15 gene	13134	0.17
chr3_104385623_104385970	1.95	Gm5546	predicted gene 5546	19183	0.13
chr13_75729670_75729828	1.93	Gm48302	predicted gene, 48302	2470	0.2
chr5_36722522_36722955	1.91	Gm43701	predicted gene 43701	25880	0.11
chr6_119196404_119196860	1.91	Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	214	0.94
chr15_77754939_77755223	1.83	Apol8	apolipoprotein L 8	158	0.91
chr2_145226076_145226374	1.83	Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	16386	0.27
chr8_13057142_13057324	1.78	Proz	protein Z, vitamin K-dependent plasma glycoprotein	3681	0.12
chr6_31613580_31613892	1.78	Gm43154	predicted gene 43154	8447	0.19
chr11_85846574_85846740	1.76	Gm11444	predicted gene 11444	3676	0.16
chr2_72269737_72269928	1.76	Map3k20	mitogen-activated protein kinase kinase kinase 20	15805	0.16
chr6_17743796_17743961	1.76	St7	suppression of tumorigenicity 7	286	0.87
chr9_46257688_46257839	1.75	Apoa5	apolipoprotein A-V	10870	0.08
chr2_163353818_163354318	1.73	Tox2	TOX high mobility group box family member 2	33690	0.12
chr8_122720852_122721185	1.73	C230057M02Rik	RIKEN cDNA C230057M02 gene	17493	0.09
chr9_32314102_32314486	1.70	Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	29943	0.14
chr15_98827029_98827236	1.70	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	1004	0.31
chr7_68010289_68010477	1.68	Igf1r	insulin-like growth factor I receptor	57556	0.13
chr8_105304651_105305257	1.68	Elmo3	engulfment and cell motility 3	647	0.33
chr5_115520920_115521071	1.67	Pxn	paxillin	690	0.48
chr1_133969397_133969709	1.67	Gm1627	predicted gene 1627	7391	0.16
chr12_85532591_85532965	1.65	Gm32296	predicted gene, 32296	3180	0.23
chr3_137940725_137941098	1.63	Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	13802	0.09
chr7_48992020_48992183	1.62	Nav2	neuron navigator 2	33004	0.14
chr14_33687535_33688054	1.62	Gm26228	predicted gene, 26228	43299	0.14
chr9_66483569_66483720	1.62	Herc1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	12911	0.16
chr5_137598572_137598723	1.61	Mospd3	motile sperm domain containing 3	2044	0.11
chrX_101290140_101290457	1.61	Med12	mediator complex subunit 12	2836	0.13
chr14_46539581_46539745	1.61	E130120K24Rik	RIKEN cDNA E130120K24 gene	16640	0.12
chr9_107312801_107313233	1.60	Gm17041	predicted gene 17041	11179	0.09
chr7_80786870_80787021	1.58	Iqgap1	IQ motif containing GTPase activating protein 1	16318	0.16
chr4_115094117_115094298	1.55	Pdzk1ip1	PDZK1 interacting protein 1	3275	0.19
chr11_59885300_59885570	1.52	Gm12714	predicted gene 12714	12939	0.11
chr10_42051090_42051241	1.51	Tdg-ps2	thymine DNA glycosylase, pseudogene 2	4141	0.24
chr10_13874715_13874984	1.51	Gm32172	predicted gene, 32172	3569	0.16
chr2_26139656_26141133	1.51	Tmem250-ps	transmembrane protein 250, pseudogene	127	0.93
chr12_80791693_80791844	1.50	Susd6	sushi domain containing 6	1209	0.31
chr4_153670421_153670572	1.50	Ajap1	adherens junction associated protein 1	187685	0.03
chr14_55824498_55825973	1.50	Nfatc4	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4	198	0.87
chr5_146703309_146703463	1.49	4930573C15Rik	RIKEN cDNA 4930573C15 gene	3236	0.24
chr17_5691251_5691421	1.49	3300005D01Rik	RIKEN cDNA 3300005D01 gene	107321	0.06
chr11_119392977_119393557	1.49	Rnf213	ring finger protein 213	167	0.93
chr1_90289010_90289204	1.49	Gm28723	predicted gene 28723	8649	0.18
chr8_120876111_120876276	1.48	Gm26878	predicted gene, 26878	4013	0.27
chr16_91433682_91433861	1.44	Gm46562	predicted gene, 46562	24650	0.08
chr11_60941469_60941717	1.44	Map2k3	mitogen-activated protein kinase kinase 3	287	0.87
chr9_71663389_71664022	1.43	Cgnl1	cingulin-like 1	15355	0.21
chr8_111312693_111312982	1.41	Mlkl	mixed lineage kinase domain-like	3282	0.18
chr7_125475659_125476258	1.41	Nsmce1	NSE1 homolog, SMC5-SMC6 complex component	2601	0.26
chr1_66157704_66157855	1.40	Map2	microtubule-associated protein 2	17494	0.24
chr11_101627503_101628296	1.40	Rdm1	RAD52 motif 1	43	0.87
chr13_58035550_58035720	1.39	Mir874	microRNA 874	12435	0.2
chr2_163658166_163658878	1.39	Pkig	protein kinase inhibitor, gamma	42	0.96
chr4_107217948_107218252	1.39	Ldlrad1	low density lipoprotein receptor class A domain containing 1	8920	0.12
chr17_26512176_26512347	1.37	Dusp1	dual specificity phosphatase 1	3742	0.13
chr12_9847846_9848083	1.37	Gm22845	predicted gene, 22845	17486	0.26
chr12_86833665_86834028	1.36	Gm10095	predicted gene 10095	12621	0.19
chr8_86707705_86707856	1.36	Gm22305	predicted gene, 22305	36437	0.11
chr13_111895198_111895356	1.35	Gm9025	predicted gene 9025	11100	0.15
chr15_79323420_79323773	1.34	Pla2g6	phospholipase A2, group VI	30	0.96
chr1_171425171_171425322	1.34	Tstd1	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1	5527	0.09
chr11_94134428_94134811	1.33	B230206L02Rik	RIKEN cDNA B230206L02 gene	1041	0.55
chr13_3750985_3751146	1.32	Gm47695	predicted gene, 47695	8760	0.15
chr2_167833383_167834006	1.31	1200007C13Rik	RIKEN cDNA 1200007C13 gene	48	0.97
chr3_101551427_101551788	1.30	Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	25953	0.16
chr6_34874530_34874844	1.30	Tmem140	transmembrane protein 140	1973	0.2
chr5_137745528_137745823	1.29	Tsc22d4	TSC22 domain family, member 4	55	0.94
chr10_100525128_100525286	1.27	Cep290	centrosomal protein 290	15247	0.14
chr7_84201425_84201608	1.27	Gm44826	predicted gene 44826	8998	0.15
chr19_24527207_24527463	1.26	Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase, type 1 beta	28454	0.16
chr11_70562053_70562579	1.26	Mink1	misshapen-like kinase 1 (zebrafish)	565	0.5
chr7_90016594_90016745	1.25	E230029C05Rik	RIKEN cDNA E230029C05 gene	12490	0.12
chr4_97690447_97690768	1.25	E130114P18Rik	RIKEN cDNA E130114P18 gene	129	0.98
chr9_65542070_65542221	1.25	Gm17749	predicted gene, 17749	12339	0.13
chr10_58497215_58497661	1.24	Ccdc138	coiled-coil domain containing 138	510	0.81
chr7_16673786_16674087	1.24	Ceacam15	carcinoembryonic antigen-related cell adhesion molecule 15	1769	0.19
chr4_43492744_43493113	1.23	Ccdc107	coiled-coil domain containing 107	28	0.6
chr16_3846598_3847298	1.23	Zfp174	zinc finger protein 174	320	0.79
chr18_68702867_68703101	1.22	Mir6356	microRNA 6356	36416	0.19
chr9_48745121_48745413	1.21	Zbtb16	zinc finger and BTB domain containing 16	90678	0.08
chr4_48750155_48750306	1.20	Gm12438	predicted gene 12438	4380	0.22
chr13_14018557_14018708	1.19	Tbce	tubulin-specific chaperone E	8788	0.12
chr11_77762866_77763395	1.19	Myo18a	myosin XVIIIA	116	0.95
chr11_115841930_115842217	1.18	Llgl2	LLGL2 scribble cell polarity complex component	7750	0.1
chr7_15948299_15949012	1.18	Nop53	NOP53 ribosome biogenesis factor	2581	0.15
chr10_80433030_80433838	1.18	Tcf3	transcription factor 3	187	0.88
chr5_114783873_114784063	1.18	Ankrd13a	ankyrin repeat domain 13a	2077	0.17
chr4_154269535_154270026	1.17	Megf6	multiple EGF-like-domains 6	6	0.97
chr6_34160067_34160249	1.17	Slc35b4	solute carrier family 35, member B4	3324	0.22
chr1_51289041_51289589	1.17	Cavin2	caveolae associated 2	189	0.95
chr5_121833479_121834291	1.17	1700008B11Rik	RIKEN cDNA 1700008B11 gene	1310	0.26
chr7_141363743_141364047	1.14	B230206H07Rik	RIKEN cDNA B230206H07 gene	1187	0.23
chr2_70920987_70921150	1.14	Gm13632	predicted gene 13632	43239	0.14
chr7_124946519_124946675	1.14	Gm45092	predicted gene 45092	38988	0.2
chr16_87716307_87716519	1.13	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	17409	0.2
chr12_111813927_111814649	1.13	Zfyve21	zinc finger, FYVE domain containing 21	47	0.85
chr4_98090122_98090275	1.12	Gm12691	predicted gene 12691	56401	0.15
chr3_57544095_57544246	1.11	Gm16016	predicted gene 16016	15938	0.16
chr9_112993623_112993789	1.10	Gm36251	predicted gene, 36251	129323	0.06
chr9_118885542_118885899	1.10	Itga9	integrin alpha 9	13651	0.16
chr1_74082945_74083347	1.10	Tns1	tensin 1	8205	0.19
chr11_94929298_94929460	1.09	Col1a1	collagen, type I, alpha 1	6845	0.12
chr9_122028487_122028684	1.09	Gm47117	predicted gene, 47117	16445	0.1
chr10_77237904_77238055	1.09	Pofut2	protein O-fucosyltransferase 2	21239	0.16
chr10_119063132_119063295	1.09	Gm33677	predicted gene, 33677	12714	0.14
chr10_37194222_37194441	1.08	5930403N24Rik	RIKEN cDNA 5930403N24 gene	53242	0.12
chr6_113373617_113373789	1.07	Tada3	transcriptional adaptor 3	2561	0.11
chr1_177475904_177476057	1.07	Gm37306	predicted gene, 37306	8602	0.17
chr2_170175772_170175948	1.07	Zfp217	zinc finger protein 217	27757	0.23
chr6_83598147_83598298	1.07	Gm7424	predicted gene 7424	3486	0.15
chr14_65833206_65833566	1.07	Esco2	establishment of sister chromatid cohesion N-acetyltransferase 2	522	0.76
chr8_80497425_80497601	1.07	Gypa	glycophorin A	3732	0.28
chr8_33993568_33993719	1.06	Gm45817	predicted gene 45817	6443	0.16
chr19_41906400_41906712	1.06	Gm46644	predicted gene, 46644	3667	0.13
chr1_58029842_58030056	1.06	Aox1	aldehyde oxidase 1	15	0.97
chr4_88032518_88033581	1.06	Mllt3	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3	232	0.71
chr1_78568303_78568542	1.06	Mogat1	monoacylglycerol O-acyltransferase 1	30794	0.13
chr6_118478826_118479369	1.05	Zfp9	zinc finger protein 9	223	0.91
chr3_84350340_84350697	1.05	4930565D16Rik	RIKEN cDNA 4930565D16 gene	29403	0.19
chr18_84772004_84772338	1.05	Gm38576	predicted gene, 38576	28104	0.11
chr2_120153745_120155075	1.04	Ehd4	EH-domain containing 4	52	0.97
chr7_24373511_24373960	1.04	Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	3397	0.11
chr4_132234845_132234996	1.03	Gmeb1	glucocorticoid modulatory element binding protein 1	14	0.94
chr13_102594195_102594486	1.02	Gm29927	predicted gene, 29927	4055	0.26
chr16_93418190_93418554	1.02	1700029J03Rik	RIKEN cDNA 1700029J03 gene	7538	0.19
chr8_123722278_123722436	1.01	6030466F02Rik	RIKEN cDNA 6030466F02 gene	11601	0.07
chr7_71603248_71603430	1.00	Gm44689	predicted gene 44689	85108	0.08
chr3_53044365_53044539	1.00	Gm42901	predicted gene 42901	2697	0.17
chr12_76319061_76319360	1.00	Akap5	A kinase (PRKA) anchor protein 5	5681	0.11
chr2_152792549_152792712	1.00	Gm23802	predicted gene, 23802	19741	0.11
chr17_26513012_26513293	0.99	Dusp1	dual specificity phosphatase 1	4633	0.12
chr18_60523320_60523681	0.99	Dctn4	dynactin 4	2685	0.23
chr14_79521380_79521761	0.98	Elf1	E74-like factor 1	5872	0.18
chr3_144689266_144689717	0.97	Sh3glb1	SH3-domain GRB2-like B1 (endophilin)	7976	0.16
chr15_11906080_11906455	0.97	Gm5144	predicted gene 5144	252	0.76
chr6_41104175_41104333	0.96	Trbv11	T cell receptor beta variable 11	2790	0.11
chr11_85310634_85310850	0.95	Ppm1d	protein phosphatase 1D magnesium-dependent, delta isoform	502	0.81
chr4_109116592_109116768	0.95	Osbpl9	oxysterol binding protein-like 9	1018	0.58
chr4_123305820_123305997	0.94	AL606917.1	keratin associated protein 10 like (KRTAP10) pseudogene	1309	0.27
chr8_121451825_121451976	0.94	Gm26784	predicted gene, 26784	16920	0.16
chr4_115497538_115497709	0.93	Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	1481	0.28
chr8_46492287_46492438	0.93	Acsl1	acyl-CoA synthetase long-chain family member 1	470	0.78
chr1_85259970_85261058	0.92	C130026I21Rik	RIKEN cDNA C130026I21 gene	1556	0.27
chr8_117199368_117199533	0.92	Gan	giant axonal neuropathy	41313	0.14
chr7_80534267_80534427	0.92	Blm	Bloom syndrome, RecQ like helicase	651	0.67
chr7_134524567_134524718	0.92	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	23482	0.25
chr5_97987046_97987205	0.92	Antxr2	anthrax toxin receptor 2	8970	0.19
chr6_6697724_6697891	0.91	Gm20618	predicted gene 20618	6286	0.21
chr17_25129751_25130048	0.91	Clcn7	chloride channel, voltage-sensitive 7	3492	0.12
chr11_90106259_90106410	0.91	Gm11494	predicted gene 11494	37290	0.15
chr3_69005511_69006175	0.91	Smc4	structural maintenance of chromosomes 4	828	0.39
chr5_104062794_104062959	0.91	Gm43333	predicted gene 43333	9449	0.1
chr2_71499426_71499577	0.90	Gm23253	predicted gene, 23253	4230	0.16
chr3_121867514_121867696	0.90	Gm42593	predicted gene 42593	4763	0.19
chr6_136555386_136555906	0.90	Atf7ip	activating transcription factor 7 interacting protein	1624	0.33
chr9_56505570_56506267	0.89	Gm47175	predicted gene, 47175	743	0.63
chr12_8357354_8358033	0.88	Gm48071	predicted gene, 48071	20976	0.14
chr15_53370344_53370653	0.88	Gm27926	predicted gene, 27926	13421	0.24
chr11_106677873_106678051	0.88	Pecam1	platelet/endothelial cell adhesion molecule 1	13385	0.16
chr2_127363383_127363699	0.88	Adra2b	adrenergic receptor, alpha 2b	255	0.89
chr7_99202007_99202158	0.88	Gm45012	predicted gene 45012	284	0.86
chr1_155810043_155810460	0.88	Qsox1	quiescin Q6 sulfhydryl oxidase 1	2569	0.18
chr7_100474794_100474973	0.87	Gm10603	predicted gene 10603	37	0.94
chr1_86527639_86529135	0.86	Ptma	prothymosin alpha	1580	0.31
chr9_21328071_21328222	0.85	Slc44a2	solute carrier family 44, member 2	7398	0.09
chr11_115832413_115832610	0.85	Llgl2	LLGL2 scribble cell polarity complex component	543	0.61
chr6_39059004_39059155	0.85	1700025N23Rik	RIKEN cDNA 1700025N23 gene	8519	0.16
chrY_90739048_90739573	0.85	Mid1-ps1	midline 1, pseudogene 1	13747	0.18
chr8_45658574_45658780	0.84	Sorbs2	sorbin and SH3 domain containing 2	1	0.98
chr5_36069536_36069852	0.84	Afap1	actin filament associated protein 1	82689	0.09
chr9_44487568_44487956	0.84	Bcl9l	B cell CLL/lymphoma 9-like	515	0.52
chr11_120229974_120230220	0.84	2900052L18Rik	RIKEN cDNA 2900052L18 gene	1488	0.23
chr2_167563411_167563937	0.84	Gm11476	predicted gene 11476	10360	0.12
chr11_117881806_117882185	0.83	Tha1	threonine aldolase 1	8514	0.1
chr7_104465078_104465376	0.82	Trim30a	tripartite motif-containing 30A	34	0.95
chr7_119785037_119785206	0.82	Eri2	exoribonuclease 2	2831	0.15
chr10_77130088_77130939	0.82	Gm7775	predicted gene 7775	6587	0.19
chr4_33923766_33925291	0.82	Cnr1	cannabinoid receptor 1 (brain)	65	0.98
chr2_125907989_125908146	0.81	Galk2	galactokinase 2	41799	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp63

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.8	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.4	1.3	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4	1.3	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.4	1.2	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.3	0.8	GO:0034421	post-translational protein acetylation(GO:0034421)
0.3	0.8	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2	1.6	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2	0.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	0.7	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2	1.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	1.0	GO:0009115	xanthine catabolic process(GO:0009115)
0.2	0.8	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2	0.9	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.2	0.7	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2	1.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2	1.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	1.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.5	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	2.2	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.1	0.4	GO:0003166	bundle of His development(GO:0003166)
0.1	0.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	0.6	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1	0.4	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.1	0.7	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.5	GO:0060374	mast cell differentiation(GO:0060374)
0.1	0.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.2	GO:1904192	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.3	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.3	GO:0097195	pilomotor reflex(GO:0097195)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.1	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.1	0.4	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.3	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.5	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.3	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.3	GO:0015888	thiamine transport(GO:0015888)
0.1	0.5	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.3	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.3	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.5	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.3	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.3	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.2	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.1	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.1	0.8	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	1.8	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.1	0.2	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.1	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	1.3	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
0.1	0.2	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	2.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.5	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.4	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	1.1	GO:0006907	pinocytosis(GO:0006907)
0.1	0.3	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.2	GO:1903416	response to glycoside(GO:1903416)
0.1	0.3	GO:0015671	oxygen transport(GO:0015671)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.2	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	0.2	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	0.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.2	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.2	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1	0.8	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	0.2	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.2	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.7	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.6	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.1	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.2	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.2	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.3	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.1	0.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.2	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	0.3	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.2	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	0.3	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.2	GO:0033131	regulation of glucokinase activity(GO:0033131)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.6	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.9	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.0	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	1.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.5	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.0	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0	0.2	GO:0033504	floor plate development(GO:0033504)
0.0	0.5	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.3	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.1	GO:0061184	dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0	0.3	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0052041	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.0	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.2	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.5	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0	0.1	GO:0001555	oocyte growth(GO:0001555)
0.0	0.5	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.0	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.2	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.4	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.1	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	0.4	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0	0.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.0	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.1	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.1	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.6	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.4	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.3	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.0	0.0	GO:0072679	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.2	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.1	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.2	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.1	GO:1900113	regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	1.2	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.2	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.3	GO:0042711	maternal behavior(GO:0042711)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0070627	ferrous iron import(GO:0070627)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.2	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.3	GO:0060669	embryonic placenta morphogenesis(GO:0060669)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0	0.1	GO:1901970	positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.1	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0042033	chemokine biosynthetic process(GO:0042033) regulation of chemokine biosynthetic process(GO:0045073)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.2	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0	0.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.4	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.0	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.0	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.0	0.6	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.0	0.1	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.0	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.4	GO:0006301	postreplication repair(GO:0006301)
0.0	0.0	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.0	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.0	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.0	1.3	GO:0000187	activation of MAPK activity(GO:0000187)
0.0	0.2	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0	0.0	GO:0021558	trochlear nerve development(GO:0021558)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0070649	polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.4	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.1	GO:0010388	cullin deneddylation(GO:0010388)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.2	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.0	0.1	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.5	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.2	GO:0034508	centromere complex assembly(GO:0034508)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.3	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.0	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.0	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.0	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.0	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.3	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.0	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.1	GO:0007614	short-term memory(GO:0007614)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.0	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.0	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.1	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.0	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.0	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	0.0	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.0	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.3	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0	0.2	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.0	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.2	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.3	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0003383	apical constriction(GO:0003383)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.0	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:1990130	Iml1 complex(GO:1990130)
0.3	2.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.3	1.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	0.8	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	0.6	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.1	1.0	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	0.5	GO:0072487	MSL complex(GO:0072487)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.2	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.2	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.3	GO:0000796	condensin complex(GO:0000796)
0.1	0.3	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.3	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.1	3.3	GO:0014704	intercalated disc(GO:0014704)
0.1	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.4	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.5	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.7	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.5	GO:0042627	chylomicron(GO:0042627)
0.0	0.3	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.6	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.6	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0097542	ciliary tip(GO:0097542)
0.0	1.1	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	1.0	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	1.4	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0005818	aster(GO:0005818)
0.0	0.0	GO:0005914	spot adherens junction(GO:0005914)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.6	1.8	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.4	1.3	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3	1.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.3	1.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.3	0.8	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.3	0.8	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.3	1.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.2	2.6	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.2	0.7	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	1.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2	0.8	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2	0.5	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.7	GO:0009378	four-way junction helicase activity(GO:0009378)
0.1	0.8	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.1	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.6	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.4	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.3	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.1	0.3	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.8	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.3	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	1.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	0.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.1	0.2	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	1.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.9	GO:0051400	BH domain binding(GO:0051400)
0.1	0.4	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.1	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.1	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.2	GO:0019961	interferon binding(GO:0019961)
0.1	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.3	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.2	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.2	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.3	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.2	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.0	0.2	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.4	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.8	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	1.1	GO:0043531	ADP binding(GO:0043531)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.3	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0043918	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.5	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.5	GO:0005112	Notch binding(GO:0005112)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.6	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0032357	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	1.0	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.2	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	1.3	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.7	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.6	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	3.1	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.0	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	1.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.4	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.4	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0018856	acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.3	GO:0043236	laminin binding(GO:0043236)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.0	GO:0015375	glycine:sodium symporter activity(GO:0015375)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.0	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	0.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	1.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	1.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.6	PID E2F PATHWAY	E2F transcription factor network
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	1.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.3	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.1	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.8	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	3.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.7	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway

Results for Trp63

Z-value: 0.99

Motif logo

Transcription factors associated with Trp63

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Trp63 motif across conditions

Conditions sorted by the z-value of the Trp63 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp63

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: