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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Arid5a

Z-value: 1.11

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Transcription factors associated with Arid5a

Gene Symbol	Gene ID	Gene Info
Arid5a Ensembl NCBI MGI UniProt	ENSMUSG00000037447.10	Arid5a

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Arid5a	chr1_36304948_36305131	2694	0.196892	-0.48	2.2e-04	Click!
Arid5a	chr1_36304680_36304831	2978	0.185889	-0.36	6.3e-03	Click!
Arid5a	chr1_36323394_36323545	6442	0.132451	-0.30	2.5e-02	Click!
Arid5a	chr1_36303331_36303632	4252	0.159341	-0.30	2.6e-02	Click!
Arid5a	chr1_36324171_36324330	7223	0.129114	-0.29	3.3e-02	Click!

Activity of the Arid5a motif across conditions

Conditions sorted by the z-value of the Arid5a motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_67221620_67221771	2.42	Gm15668	predicted gene 15668	27505	0.19
chr10_78753316_78753475	2.31	Ccdc105	coiled-coil domain containing 105	330	0.82
chr8_55034088_55034270	1.92	Gm45264	predicted gene 45264	5778	0.14
chr7_105600032_105600389	1.69	Hpx	hemopexin	73	0.94
chr7_44603776_44603927	1.66	Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	7758	0.08
chr2_58755284_58755435	1.65	Upp2	uridine phosphorylase 2	147	0.96
chr16_84920068_84920254	1.60	Gm49568	predicted gene, 49568	26329	0.14
chr3_4796668_4797120	1.60	1110015O18Rik	RIKEN cDNA 1110015O18 gene	664	0.77
chr8_71602133_71603459	1.59	Fam129c	family with sequence similarity 129, member C	445	0.63
chr12_49951906_49952207	1.53	Gm7481	predicted gene 7481	110305	0.07
chr18_22343488_22344114	1.53	Asxl3	additional sex combs like 3, transcriptional regulator	445	0.91
chr14_36969226_36969443	1.43	Ccser2	coiled-coil serine rich 2	557	0.79
chr12_84198469_84198620	1.43	Gm31513	predicted gene, 31513	2575	0.16
chr10_32301324_32301530	1.40	C030006N10Rik	RIKEN cDNA C030006N10 gene	21734	0.2
chr10_22479940_22480092	1.38	Gm26585	predicted gene, 26585	26496	0.17
chr13_69263758_69264115	1.36	Gm4812	predicted gene 4812	81719	0.09
chr3_84034408_84034678	1.35	Tmem131l	transmembrane 131 like	5585	0.25
chr13_104595017_104595179	1.33	2610204G07Rik	RIKEN cDNA 2610204G07 gene	89833	0.09
chr4_49572335_49572486	1.28	Tmem246	transmembrane protein 246	21480	0.13
chr8_84927654_84927805	1.26	Mast1	microtubule associated serine/threonine kinase 1	1046	0.24
chr8_90669516_90669667	1.25	Gm45639	predicted gene 45639	5367	0.21
chr11_35280959_35281110	1.24	Gm12123	predicted gene 12123	42636	0.16
chr7_107693030_107693181	1.22	Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	27794	0.13
chr3_57386534_57386685	1.22	Gm5276	predicted gene 5276	24221	0.18
chr1_124652334_124652530	1.21	Gm28299	predicted gene 28299	36836	0.22
chr1_19211898_19212189	1.19	Tfap2b	transcription factor AP-2 beta	11	0.98
chr13_100026063_100026214	1.19	Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	10499	0.19
chr12_14056141_14056292	1.17	Gm48480	predicted gene, 48480	25864	0.19
chr11_88356603_88356961	1.13	Gm15893	predicted gene 15893	491	0.76
chr9_10230307_10230458	1.12	Gm24496	predicted gene, 24496	60205	0.14
chr7_38184556_38184765	1.10	1600014C10Rik	RIKEN cDNA 1600014C10 gene	762	0.52
chr7_96555432_96555583	1.09	Tenm4	teneurin transmembrane protein 4	33109	0.2
chr4_68595404_68595555	1.07	Brinp1	bone morphogenic protein/retinoic acid inducible neural specific 1	233879	0.02
chr7_64741665_64742004	1.07	Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	2005	0.39
chr8_64790589_64790740	1.05	Klhl2	kelch-like 2, Mayven	9000	0.16
chr8_114592030_114592212	1.03	Gm16116	predicted gene 16116	2779	0.29
chr3_53207177_53207328	1.03	Lhfp	lipoma HMGIC fusion partner	22073	0.18
chr13_81329913_81330086	1.03	Adgrv1	adhesion G protein-coupled receptor V1	12837	0.26
chr8_17537632_17537783	1.01	Csmd1	CUB and Sushi multiple domains 1	2121	0.49
chr10_87032765_87033054	0.99	Stab2	stabilin 2	24884	0.14
chr10_20286388_20286827	0.98	Gm48249	predicted gene, 48249	19	0.96
chr3_136677756_136677907	0.96	Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	7061	0.23
chr8_98065388_98065708	0.96	Gm17997	predicted gene, 17997	131967	0.05
chr10_63410259_63410415	0.95	Gm7530	predicted gene 7530	2662	0.19
chr13_114460147_114460556	0.94	Fst	follistatin	1400	0.31
chr8_123813265_123813430	0.93	Rab4a	RAB4A, member RAS oncogene family	7279	0.1
chr5_101524000_101524342	0.90	Gm43103	predicted gene 43103	17842	0.24
chr8_9934851_9935294	0.88	Gm10067	predicted gene 10067	15609	0.16
chr13_75992746_75992897	0.87	Spata9	spermatogenesis associated 9	25074	0.1
chr3_138263607_138263758	0.87	Adh1	alcohol dehydrogenase 1 (class I)	2691	0.18
chr17_75876974_75877125	0.87	Gm4710	predicted gene 4710	16026	0.25
chr18_69834677_69834850	0.87	Gm50215	predicted gene, 50215	75961	0.1
chr3_79818299_79818691	0.86	Gm26420	predicted gene, 26420	16438	0.17
chr14_122607548_122607718	0.85	Gm49259	predicted gene, 49259	2480	0.27
chr4_111553060_111553213	0.84	Agbl4	ATP/GTP binding protein-like 4	13559	0.27
chr3_127626187_127626399	0.84	Neurog2	neurogenin 2	6842	0.13
chr6_148338244_148338395	0.84	Rps4l	ribosomal protein S4-like	16337	0.15
chr6_145918369_145918520	0.84	Sspn	sarcospan	13197	0.16
chr11_64188058_64188518	0.84	Gm12290	predicted gene 12290	23715	0.24
chr5_20583062_20583213	0.83	Gm3544	predicted gene 3544	5459	0.25
chr5_111602149_111602572	0.82	Gm42489	predicted gene 42489	8744	0.21
chr17_62784634_62784785	0.82	Efna5	ephrin A5	96435	0.09
chr3_77831850_77832047	0.82	Gm37576	predicted gene, 37576	41205	0.19
chr2_27981631_27981939	0.82	Col5a1	collagen, type V, alpha 1	35656	0.15
chr9_102975978_102976271	0.81	Slco2a1	solute carrier organic anion transporter family, member 2a1	12588	0.17
chr6_5198692_5198843	0.81	Pon1	paraoxonase 1	4821	0.21
chr16_67061894_67062045	0.81	Cadm2	cell adhesion molecule 2	108635	0.07
chr4_114780370_114780653	0.81	Gm12830	predicted gene 12830	41211	0.14
chr7_3684248_3684455	0.78	Mboat7	membrane bound O-acyltransferase domain containing 7	177	0.85
chr2_157801820_157801971	0.78	Ctnnbl1	catenin, beta like 1	12031	0.21
chr13_81343337_81343488	0.77	Adgrv1	adhesion G protein-coupled receptor V1	97	0.98
chr7_119251734_119252076	0.76	Gm4083	predicted gene 4083	49802	0.12
chr5_90690248_90690399	0.75	Rassf6	Ras association (RalGDS/AF-6) domain family member 6	49666	0.09
chr8_40869481_40869728	0.75	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	5344	0.17
chr10_30000963_30001114	0.74	Gm48215	predicted gene, 48215	394	0.88
chr6_129333639_129333791	0.73	Clec2m	C-type lectin domain family 2, member m	1919	0.23
chr3_123690157_123690344	0.73	Ndst3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	30	0.97
chr1_25107573_25107724	0.73	Gm29414	predicted gene 29414	80416	0.07
chrX_57712548_57712699	0.72	Gm8107	predicted gene 8107	25932	0.14
chr12_112221644_112222111	0.72	Gm20368	predicted gene, 20368	16724	0.17
chr9_96924055_96924211	0.72	Gm8524	predicted gene 8524	18626	0.14
chr1_91708999_91709150	0.72	Twist2	twist basic helix-loop-helix transcription factor 2	92387	0.06
chr17_93409383_93409594	0.71	Gm50001	predicted gene, 50001	17790	0.24
chr1_68047124_68047492	0.71	Gm15671	predicted gene 15671	23065	0.22
chr1_23282966_23283129	0.71	Gm27028	predicted gene, 27028	8490	0.12
chr10_22579573_22579724	0.71	Slc2a12	solute carrier family 2 (facilitated glucose transporter), member 12	65363	0.1
chr15_51941440_51941591	0.71	Gm48923	predicted gene, 48923	44428	0.11
chr1_20132404_20132557	0.70	Gm37315	predicted gene, 37315	66932	0.14
chr6_101904608_101904759	0.70	Gm44177	predicted gene, 44177	8590	0.26
chr13_18868291_18868517	0.70	Vps41	VPS41 HOPS complex subunit	23541	0.19
chr2_60863248_60863595	0.70	Rbms1	RNA binding motif, single stranded interacting protein 1	18017	0.26
chr4_76144837_76144988	0.69	Ptprd	protein tyrosine phosphatase, receptor type, D	10769	0.31
chr10_130469983_130470134	0.69	Gm18755	predicted gene, 18755	551	0.68
chr1_179104589_179104740	0.69	Smyd3	SET and MYND domain containing 3	115319	0.07
chr6_63964350_63964529	0.69	Gm44072	predicted gene, 44072	77118	0.11
chr14_19977737_19977924	0.69	Gng2	guanine nucleotide binding protein (G protein), gamma 2	203	0.95
chr8_73920568_73920719	0.68	Gm7948	predicted gene 7948	48950	0.19
chr7_107699967_107700118	0.68	Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	34731	0.11
chr12_13984177_13984402	0.68	Gm48479	predicted gene, 48479	28795	0.19
chr6_15839943_15840094	0.66	Gm43990	predicted gene, 43990	3929	0.29
chr8_70618980_70619268	0.65	Lrrc25	leucine rich repeat containing 25	2280	0.14
chr3_34322517_34323142	0.65	Gm38505	predicted gene, 38505	28883	0.19
chr3_126505619_126505770	0.65	Gm20568	predicted gene, 20568	57951	0.09
chr10_46718374_46718662	0.65	Gm19994	predicted gene, 19994	48374	0.16
chr5_89450856_89451007	0.64	Gc	vitamin D binding protein	6967	0.25
chr12_29096469_29096838	0.63	4833405L11Rik	RIKEN cDNA 4833405L11 gene	10084	0.23
chr13_81639716_81639899	0.63	Adgrv1	adhesion G protein-coupled receptor V1	6653	0.19
chr17_22866359_22866541	0.63	Zfp945	zinc finger protein 945	655	0.63
chr4_53120135_53120286	0.63	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	39685	0.15
chr5_51868161_51868312	0.63	Gm43606	predicted gene 43606	9461	0.17
chr7_29179376_29179536	0.62	Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	435	0.62
chr5_74242721_74242993	0.62	Gm42599	predicted gene 42599	6759	0.17
chr9_10529630_10529781	0.62	Gm46103	predicted gene, 46103	53770	0.16
chr9_63651656_63651889	0.62	Aagab	alpha- and gamma-adaptin binding protein	13119	0.19
chr8_34456648_34456799	0.61	Gm45349	predicted gene 45349	16272	0.17
chr1_174637558_174637709	0.60	Fmn2	formin 2	25084	0.24
chr15_10202683_10202834	0.60	Prlr	prolactin receptor	10707	0.28
chr3_86779786_86779937	0.60	Gm37876	predicted gene, 37876	1208	0.49
chr14_22708470_22708671	0.60	Gm7473	predicted gene 7473	66674	0.13
chr13_28552152_28552303	0.59	2610307P16Rik	RIKEN cDNA 2610307P16 gene	31119	0.19
chr12_55983531_55983948	0.59	Gm5183	predicted gene 5183	66794	0.09
chr1_20905491_20905707	0.59	Gm24171	predicted gene, 24171	9941	0.12
chr13_107075011_107075174	0.59	Gm31452	predicted gene, 31452	11397	0.17
chr2_35103638_35103965	0.59	AI182371	expressed sequence AI182371	2258	0.25
chrX_10841412_10841563	0.59	Gm14473	predicted gene 14473	24146	0.22
chr7_98935304_98935457	0.59	Gm23479	predicted gene, 23479	514	0.74
chr2_65845289_65845528	0.59	Csrnp3	cysteine-serine-rich nuclear protein 3	359	0.89
chr2_172934901_172935069	0.58	Bmp7	bone morphogenetic protein 7	5107	0.21
chr5_145881304_145881464	0.58	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	1420	0.38
chr4_129206921_129207085	0.58	Yars	tyrosyl-tRNA synthetase	2535	0.19
chr9_74862086_74862680	0.58	Onecut1	one cut domain, family member 1	462	0.77
chr3_127367544_127367695	0.58	Gm42969	predicted gene 42969	26087	0.13
chr15_91180038_91180189	0.58	Abcd2	ATP-binding cassette, sub-family D (ALD), member 2	7928	0.21
chr5_40294986_40295137	0.57	Gm2810	predicted pseudogene 2810	33377	0.24
chr18_64182442_64182593	0.57	St8sia3os	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand	13713	0.15
chr5_108674685_108675069	0.57	Slc26a1	solute carrier family 26 (sulfate transporter), member 1	92	0.94
chrX_77473650_77473824	0.57	Gm5937	predicted gene 5937	17151	0.21
chr17_84422138_84422289	0.57	Thada	thyroid adenoma associated	13475	0.2
chr7_99170033_99170322	0.57	Dgat2	diacylglycerol O-acyltransferase 2	71	0.96
chr6_137100379_137100530	0.57	Rerg	RAS-like, estrogen-regulated, growth-inhibitor	39609	0.15
chr5_88699513_88699664	0.56	Mob1b	MOB kinase activator 1B	21267	0.13
chr6_17377488_17377690	0.56	Gm15581	predicted gene 15581	8015	0.19
chr5_76528839_76528990	0.56	Exoc1	exocyst complex component 1	397	0.85
chr8_102027364_102027515	0.56	Gm22223	predicted gene, 22223	487731	0.01
chr5_39856661_39857212	0.56	Gm7816	predicted pseudogene 7816	58722	0.14
chr1_166429081_166429243	0.56	Gm16418	predicted pseudogene 16418	2713	0.21
chr5_105826866_105827017	0.56	Lrrc8d	leucine rich repeat containing 8D	2430	0.21
chr12_27083107_27083496	0.56	Gm9866	predicted gene 9866	31694	0.24
chr11_68274100_68274260	0.55	Gm12305	predicted gene 12305	3301	0.28
chr8_45264500_45264652	0.55	F11	coagulation factor XI	2545	0.25
chr10_119721989_119722201	0.55	Grip1	glutamate receptor interacting protein 1	30041	0.16
chr19_21409302_21409461	0.55	Gda	guanine deaminase	31478	0.2
chr5_67539883_67540078	0.54	1700025A08Rik	RIKEN cDNA 1700025A08 gene	67846	0.07
chr5_39126248_39126431	0.54	Gm42857	predicted gene 42857	123308	0.05
chr15_54768397_54768584	0.54	Gm7577	predicted gene 7577	2977	0.3
chr1_59174641_59174801	0.53	Mpp4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	11332	0.13
chr8_48731254_48731405	0.53	Tenm3	teneurin transmembrane protein 3	56639	0.15
chr14_104567727_104567899	0.53	Gm22021	predicted gene, 22021	23281	0.16
chr15_74175414_74175565	0.53	Gm15387	predicted gene 15387	81156	0.09
chr2_4587704_4588084	0.53	Gm13179	predicted gene 13179	607	0.75
chr16_78238212_78238715	0.53	Gm25916	predicted gene, 25916	1795	0.31
chr15_22046957_22047266	0.52	Gm49187	predicted gene, 49187	88679	0.1
chr11_113308657_113308808	0.52	4732490B19Rik	RIKEN cDNA 4732490B19 gene	99063	0.07
chr2_162662555_162662859	0.52	9430021M05Rik	RIKEN cDNA 9430021M05 gene	1544	0.3
chr1_50647049_50647200	0.52	Gm20118	predicted gene, 20118	114094	0.07
chr16_72639633_72639784	0.52	Robo1	roundabout guidance receptor 1	23441	0.28
chr8_104023095_104023520	0.51	Gm8748	predicted gene 8748	47842	0.12
chr6_23272869_23273356	0.50	C130093G08Rik	RIKEN cDNA C130093G08 gene	21979	0.16
chr17_11990784_11990935	0.50	Prkn	parkin RBR E3 ubiquitin protein ligase	39057	0.2
chr7_108797287_108797500	0.50	Gm45232	predicted gene 45232	2390	0.19
chr4_108074585_108074736	0.50	Scp2	sterol carrier protein 2, liver	3241	0.18
chr15_18190282_18190433	0.49	Gm8318	predicted gene 8318	26476	0.22
chr4_141755113_141755264	0.49	Agmat	agmatine ureohydrolase (agmatinase)	8516	0.12
chr4_150426480_150426643	0.49	Rere	arginine glutamic acid dipeptide (RE) repeats	20167	0.22
chr8_20423824_20423975	0.49	2610005L07Rik	RIKEN cDNA 2610005L07 gene	915	0.61
chr17_47981564_47981928	0.49	Gm14871	predicted gene 14871	21826	0.12
chr4_84432234_84432385	0.49	Gm12421	predicted gene 12421	3185	0.36
chr14_59883614_59883765	0.48	Gm9013	predicted gene 9013	156802	0.03
chr2_63669522_63669680	0.48	Gm23503	predicted gene, 23503	237407	0.02
chr10_21444559_21444841	0.48	Gm48386	predicted gene, 48386	936	0.49
chr8_48322987_48323138	0.47	Tenm3	teneurin transmembrane protein 3	22963	0.23
chr19_38356392_38356694	0.47	Gm50150	predicted gene, 50150	13929	0.14
chr10_20954548_20954710	0.47	Ahi1	Abelson helper integration site 1	2004	0.38
chrX_7322411_7322562	0.47	Clcn5	chloride channel, voltage-sensitive 5	3128	0.2
chr12_101958652_101958891	0.46	Atxn3	ataxin 3	525	0.72
chr13_69700758_69700909	0.46	Gm48819	predicted gene, 48819	3022	0.14
chr14_98833753_98833964	0.45	Gm49018	predicted gene, 49018	87087	0.08
chr3_158560332_158560585	0.45	Lrrc7	leucine rich repeat containing 7	878	0.73
chr5_49329145_49329296	0.45	Kcnip4	Kv channel interacting protein 4	43561	0.13
chr17_63979339_63979498	0.45	Fer	fer (fms/fps related) protein kinase	41446	0.2
chr13_96985086_96985237	0.45	Gm48609	predicted gene, 48609	30138	0.12
chr3_37917343_37917494	0.45	Gm20755	predicted gene, 20755	18605	0.15
chr6_103431040_103431244	0.44	Chl1	cell adhesion molecule L1-like	79444	0.09
chr1_23335200_23335354	0.44	Gm20954	predicted gene, 20954	11322	0.15
chr2_118451199_118451350	0.44	Eif2ak4	eukaryotic translation initiation factor 2 alpha kinase 4	5886	0.17
chr15_36914867_36915038	0.44	Gm41300	predicted gene, 41300	16734	0.15
chr5_109466914_109467109	0.44	Gm18555	predicted gene, 18555	6385	0.19
chr2_66171763_66171914	0.43	Gm13618	predicted gene 13618	15998	0.16
chr2_5590130_5590305	0.43	Gm13216	predicted gene 13216	13354	0.26
chr16_93874975_93875126	0.43	Chaf1b	chromatin assembly factor 1, subunit B (p60)	8851	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5a

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2	1.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	1.2	GO:0097070	ductus arteriosus closure(GO:0097070)
0.1	0.3	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	0.5	GO:0019532	oxalate transport(GO:0019532)
0.1	0.5	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1	0.3	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1	0.3	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.1	0.2	GO:0071873	response to norepinephrine(GO:0071873)
0.1	0.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	0.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.5	GO:0051601	exocyst localization(GO:0051601)
0.0	0.2	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.6	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.2	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:2000832	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.4	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.4	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.3	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.2	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.3	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.0	0.1	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.0	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.1	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.0	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.0	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	1.6	GO:0009166	nucleotide catabolic process(GO:0009166)
0.0	0.1	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.0	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.1	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.6	GO:0001964	startle response(GO:0001964)
0.0	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.2	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.2	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.0	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	1.0	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0060618	nipple development(GO:0060618)
0.0	0.0	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.3	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.2	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.0	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.6	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0000237	leptotene(GO:0000237)
0.0	0.0	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.1	GO:0043129	surfactant homeostasis(GO:0043129)
0.0	0.1	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.0	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.0	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.0	GO:1901660	calcium ion export(GO:1901660)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.0	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.7	GO:0045098	type III intermediate filament(GO:0045098)
0.3	1.2	GO:1990696	USH2 complex(GO:1990696)
0.1	0.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	0.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.2	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.4	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.5	GO:0000145	exocyst(GO:0000145)
0.0	0.4	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.0	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	1.6	GO:0072562	blood microparticle(GO:0072562)
0.0	0.0	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0015232	heme transporter activity(GO:0015232)
0.2	0.5	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.2	0.7	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	1.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.3	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.4	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	0.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	0.7	GO:0071617	lysophospholipid acyltransferase activity(GO:0071617)
0.1	0.7	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.3	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.0	0.0	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0	1.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0036042	phosphatidylcholine transporter activity(GO:0008525) long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	1.0	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0043919	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0044606	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	PID ALK2 PATHWAY	ALK2 signaling events
1.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters