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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Bbx

Z-value: 0.86

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Transcription factors associated with Bbx

Gene Symbol	Gene ID	Gene Info
Bbx Ensembl NCBI MGI UniProt	ENSMUSG00000022641.9	Bbx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Bbx	chr16_50309458_50309740	21394	0.272779	-0.47	3.1e-04	Click!
Bbx	chr16_50309820_50310005	21081	0.273717	-0.37	4.9e-03	Click!
Bbx	chr16_50381432_50381608	48392	0.178932	-0.37	5.1e-03	Click!
Bbx	chr16_50381060_50381246	48759	0.177910	-0.34	1.0e-02	Click!
Bbx	chr16_50221248_50221422	109658	0.068622	-0.28	3.6e-02	Click!

Activity of the Bbx motif across conditions

Conditions sorted by the z-value of the Bbx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_121348775_121349004	2.05	Hs3st2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	42970	0.13
chrX_102418826_102418977	2.01	Hdac8	histone deacetylase 8	85840	0.07
chr7_87371496_87371647	2.00	Tyr	tyrosinase	121821	0.05
chr2_84338187_84338338	1.97	Gm13711	predicted gene 13711	19951	0.19
chr4_49548338_49548489	1.93	Aldob	aldolase B, fructose-bisphosphate	1133	0.41
chrX_9256889_9257156	1.93	Gm14862	predicted gene 14862	123	0.95
chr13_21924698_21924984	1.68	Gm44456	predicted gene, 44456	175	0.85
chr9_102656851_102657023	1.66	Anapc13	anaphase promoting complex subunit 13	28425	0.1
chr19_11724358_11724660	1.66	Gm19224	predicted gene, 19224	20408	0.08
chr17_57796735_57796897	1.65	Cntnap5c	contactin associated protein-like 5C	27246	0.14
chr6_128551311_128551462	1.65	A2ml1	alpha-2-macroglobulin like 1	1892	0.19
chr10_100155713_100155864	1.60	Gm25287	predicted gene, 25287	11534	0.13
chr10_45001413_45001580	1.54	Gm4795	predicted pseudogene 4795	4614	0.19
chr8_128424742_128424907	1.48	Nrp1	neuropilin 1	65427	0.12
chr2_151037749_151037912	1.43	Nanp	N-acetylneuraminic acid phosphatase	1532	0.22
chr1_163477892_163478043	1.42	Gorab	golgin, RAB6-interacting	74298	0.09
chr2_171633456_171634007	1.39	Gm26489	predicted gene, 26489	327300	0.01
chr2_151563537_151563699	1.39	Sdcbp2	syndecan binding protein (syntenin) 2	9004	0.13
chr6_30477529_30477700	1.38	Tmem209	transmembrane protein 209	14565	0.12
chr11_101556560_101556853	1.35	Nbr1	NBR1, autophagy cargo receptor	534	0.6
chr3_80780882_80781033	1.35	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	21622	0.23
chr5_14960858_14961009	1.29	Gm10354	predicted gene 10354	18002	0.18
chr4_145000143_145000472	1.28	Vps13d	vacuolar protein sorting 13D	16346	0.21
chr15_47761459_47761610	1.25	Gm23530	predicted gene, 23530	39139	0.19
chr4_121014564_121014855	1.24	Smap2	small ArfGAP 2	2538	0.19
chr2_167492358_167493413	1.21	Spata2	spermatogenesis associated 2	2	0.76
chr13_91807162_91808007	1.19	Zcchc9	zinc finger, CCHC domain containing 9	77	0.97
chr16_23511404_23511561	1.19	Gm49514	predicted gene, 49514	2788	0.2
chr4_95141587_95141785	1.18	Gm28096	predicted gene 28096	10054	0.16
chr17_63979339_63979498	1.15	Fer	fer (fms/fps related) protein kinase	41446	0.2
chr10_36484838_36485024	1.15	Hs3st5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	21883	0.26
chr9_32005374_32005525	1.15	Gm47465	predicted gene, 47465	11	0.97
chr6_135325338_135325489	1.14	Gm44275	predicted gene, 44275	5852	0.13
chr6_103616019_103616201	1.14	Gm44436	predicted gene, 44436	147	0.95
chr16_4100574_4100725	1.13	Crebbp	CREB binding protein	4523	0.15
chr10_123089632_123089795	1.12	Mon2	MON2 homolog, regulator of endosome to Golgi trafficking	13208	0.19
chr6_139882188_139882339	1.09	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	35720	0.16
chr7_5060805_5061447	1.08	Gm45133	predicted gene 45133	923	0.22
chr14_87566978_87567524	1.07	Tdrd3	tudor domain containing 3	28152	0.2
chr10_61412962_61413255	1.06	Nodal	nodal	4864	0.13
chr5_99099723_99099909	1.05	Prkg2	protein kinase, cGMP-dependent, type II	62465	0.11
chr9_110422694_110422845	1.05	Ngp	neutrophilic granule protein	3022	0.17
chr10_99189347_99189498	1.05	Poc1b	POC1 centriolar protein B	3470	0.16
chr2_174291748_174291899	1.04	Gnasas1	GNAS antisense RNA 1	3566	0.16
chr17_64961925_64962076	1.04	Gm25344	predicted gene, 25344	17148	0.25
chr3_60168628_60168801	1.04	Gm24382	predicted gene, 24382	40967	0.17
chr1_175028715_175029238	1.03	Rgs7	regulator of G protein signaling 7	49969	0.17
chr3_60169438_60169604	1.03	Gm24382	predicted gene, 24382	41774	0.16
chr4_142221224_142221954	1.02	Kazn	kazrin, periplakin interacting protein	11383	0.22
chr10_68444362_68444513	1.02	Cabcoco1	ciliary associated calcium binding coiled-coil 1	81330	0.09
chr5_108451688_108451839	1.02	Mfsd7a	major facilitator superfamily domain containing 7A	2663	0.15
chr4_138938899_138939064	1.00	Otud3	OTU domain containing 3	25036	0.12
chr16_72510448_72511408	0.99	Robo1	roundabout guidance receptor 1	52772	0.18
chr13_21170243_21170544	0.98	Trim27	tripartite motif-containing 27	9052	0.13
chr1_191882872_191883023	0.98	1700034H15Rik	RIKEN cDNA 1700034H15 gene	16182	0.14
chr17_6731741_6732102	0.97	Ezr	ezrin	10900	0.16
chr3_83015499_83015650	0.97	Gm30097	predicted gene, 30097	7086	0.14
chr12_46698300_46698451	0.95	Gm33869	predicted gene, 33869	5841	0.15
chr13_75385061_75385212	0.92	Gm48234	predicted gene, 48234	94251	0.07
chr12_54256573_54256724	0.91	Gm24692	predicted gene, 24692	15748	0.14
chr6_90561220_90561762	0.91	Aldh1l1	aldehyde dehydrogenase 1 family, member L1	6215	0.15
chr13_100409933_100410098	0.90	Rpl31-ps13	ribosomal protein L31, pseudogene 13	5550	0.15
chr9_61370339_61371660	0.89	Gm10655	predicted gene 10655	628	0.63
chr8_46446597_46446889	0.88	Gm45245	predicted gene 45245	5561	0.16
chr3_144201827_144203140	0.88	Lmo4	LIM domain only 4	87	0.97
chr13_7698051_7698203	0.88	Gm48252	predicted gene, 48252	55151	0.14
chr14_14351950_14353283	0.87	Il3ra	interleukin 3 receptor, alpha chain	2995	0.15
chr12_100725043_100725700	0.86	Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	251	0.91
chr2_137880540_137880691	0.85	Gm14062	predicted gene 14062	3784	0.38
chrX_16836560_16836772	0.83	Maob	monoamine oxidase B	19300	0.26
chr6_82052849_82053004	0.83	Gm15864	predicted gene 15864	345	0.67
chr5_91038675_91038962	0.83	Epgn	epithelial mitogen	11354	0.17
chr7_111003851_111004038	0.82	Mrvi1	MRV integration site 1	21483	0.15
chr14_99305409_99305608	0.82	Klf5	Kruppel-like factor 5	6354	0.17
chr18_84857828_84857986	0.82	Gm16146	predicted gene 16146	1640	0.31
chr5_15019515_15019782	0.82	Gm17019	predicted gene 17019	13350	0.22
chr11_44683091_44683242	0.82	Gm12158	predicted gene 12158	20490	0.2
chr14_76805109_76805269	0.82	Gm30246	predicted gene, 30246	24362	0.16
chr16_32563013_32563416	0.81	Gm34680	predicted gene, 34680	11472	0.14
chr11_106274798_106274991	0.80	Tcam1	testicular cell adhesion molecule 1	1778	0.17
chr13_100284737_100284888	0.79	Naip3-ps1	NLR family, apoptosis inhibitory protein 3, pseudogene 1	5995	0.17
chr3_67867676_67867912	0.79	Iqcj	IQ motif containing J	24426	0.19
chr1_85333250_85333459	0.78	Gm2619	predicted gene 2619	6069	0.14
chr2_6285591_6285742	0.78	Gm13383	predicted gene 13383	28400	0.14
chr2_148393301_148393467	0.78	Sstr4	somatostatin receptor 4	1960	0.3
chr12_80112847_80113228	0.77	Zfp36l1	zinc finger protein 36, C3H type-like 1	24	0.96
chr5_15591695_15592053	0.77	Gm30613	predicted gene, 30613	13192	0.14
chr5_137472693_137472990	0.77	Zan	zonadhesin	3754	0.11
chr16_26991829_26992040	0.76	Gmnc	geminin coiled-coil domain containing	282	0.95
chr13_19364615_19364766	0.76	Stard3nl	STARD3 N-terminal like	3265	0.26
chr17_3556298_3556461	0.76	Tfb1m	transcription factor B1, mitochondrial	1355	0.33
chr13_56139567_56139718	0.76	Macroh2a1	macroH2A.1 histone	3281	0.22
chr9_124425359_124425530	0.75	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	1290	0.39
chr7_99582614_99582765	0.75	Arrb1	arrestin, beta 1	9625	0.11
chr12_111353338_111354089	0.74	Cdc42bpb	CDC42 binding protein kinase beta	23906	0.13
chr8_76913114_76913300	0.73	Nr3c2	nuclear receptor subfamily 3, group C, member 2	4935	0.24
chr7_55332148_55332299	0.73	Gm44898	predicted gene 44898	56287	0.13
chr3_113699092_113699243	0.72	Gm17775	predicted gene, 17775	30065	0.19
chr14_14354416_14355184	0.72	Il3ra	interleukin 3 receptor, alpha chain	5179	0.12
chr6_67013417_67013625	0.72	Gm15644	predicted gene 15644	1036	0.38
chr19_4593871_4594048	0.71	Pcx	pyruvate carboxylase	387	0.78
chr7_128003368_128003519	0.71	Trim72	tripartite motif-containing 72	506	0.52
chr18_25097355_25097753	0.71	Fhod3	formin homology 2 domain containing 3	26807	0.22
chr5_147758193_147758351	0.71	Gm43156	predicted gene 43156	12756	0.19
chr13_90502235_90502410	0.70	Gm21726	predicted gene, 21726	81007	0.09
chr4_19970756_19970907	0.70	4930480G23Rik	RIKEN cDNA 4930480G23 gene	27893	0.17
chr13_114793412_114793586	0.70	Mocs2	molybdenum cofactor synthesis 2	24737	0.23
chr4_77310465_77310616	0.69	Gm23159	predicted gene, 23159	352042	0.01
chr3_155777141_155777292	0.69	Gm37324	predicted gene, 37324	1388	0.43
chr15_59520085_59520242	0.69	Gm36677	predicted gene, 36677	98427	0.07
chr16_52333248_52333399	0.69	Alcam	activated leukocyte cell adhesion molecule	36399	0.23
chr2_24720034_24720185	0.69	Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	34241	0.13
chr5_134914340_134914552	0.67	Cldn13	claudin 13	1080	0.29
chr1_168295882_168296042	0.67	Gm37524	predicted gene, 37524	41709	0.18
chr5_50794878_50795077	0.67	Gm43014	predicted gene 43014	43340	0.19
chr18_25655666_25655955	0.67	0710001A04Rik	RIKEN cDNA 0710001A04 gene	57960	0.13
chr4_99249480_99249645	0.66	Gm10305	predicted gene 10305	23109	0.15
chr15_101177114_101177265	0.66	Acvr1b	activin A receptor, type 1B	3122	0.15
chr19_47053280_47053431	0.66	Gm50319	predicted gene, 50319	1893	0.18
chr12_80114135_80114615	0.66	Zfp36l1	zinc finger protein 36, C3H type-like 1	1362	0.27
chr11_56069627_56069962	0.65	Nmur2	neuromedin U receptor 2	28784	0.25
chr5_146021259_146021424	0.65	Gm8454	predicted gene 8454	3500	0.16
chr9_71164075_71164226	0.64	Gm32511	predicted gene, 32511	356	0.75
chr4_89433459_89434002	0.64	Gm12608	predicted gene 12608	10914	0.19
chr15_63709612_63709777	0.63	4930449C09Rik	RIKEN cDNA 4930449C09 gene	8124	0.14
chr8_68613276_68613575	0.63	Gm15654	predicted gene 15654	6713	0.28
chr7_123448677_123449086	0.63	Aqp8	aquaporin 8	13410	0.18
chr3_106495488_106495639	0.63	Dennd2d	DENN/MADD domain containing 2D	2388	0.21
chr10_111073345_111073645	0.63	Gm48851	predicted gene, 48851	29376	0.14
chr12_111246912_111247092	0.62	Traf3	TNF receptor-associated factor 3	1481	0.35
chr8_127514893_127515068	0.62	Gm6921	predicted pseudogene 6921	46455	0.16
chr5_62622956_62623107	0.61	Gm43237	predicted gene 43237	9573	0.2
chr8_8225399_8225550	0.61	A630009H07Rik	RIKEN cDNA A630009H07 gene	109603	0.06
chr11_22055931_22056082	0.61	Otx1	orthodenticle homeobox 1	53109	0.15
chr13_63567343_63568686	0.60	A930032L01Rik	RIKEN cDNA A930032L01 gene	40	0.96
chr10_62530548_62530699	0.60	Srgn	serglycin	3172	0.18
chr4_133552955_133553552	0.60	Nr0b2	nuclear receptor subfamily 0, group B, member 2	123	0.92
chr13_95531340_95531619	0.60	Gm48730	predicted gene, 48730	4111	0.18
chr10_44427597_44427753	0.60	Gm35028	predicted gene, 35028	3351	0.25
chr5_41842836_41842987	0.59	Bod1l	biorientation of chromosomes in cell division 1-like	1381	0.44
chr11_112720530_112720814	0.59	BC006965	cDNA sequence BC006965	9309	0.26
chr19_10277406_10277748	0.59	Gm30042	predicted gene, 30042	13349	0.13
chr10_121604767_121604918	0.59	Xpot	exportin, tRNA (nuclear export receptor for tRNAs)	244	0.9
chr3_14877046_14877264	0.58	Car3	carbonic anhydrase 3	7977	0.19
chr12_57537131_57537289	0.58	Foxa1	forkhead box A1	8911	0.15
chr1_91442484_91442930	0.58	Per2	period circadian clock 2	7158	0.12
chr4_131041413_131041564	0.58	A930031H19Rik	RIKEN cDNA A930031H19 gene	31014	0.18
chr1_139096497_139096648	0.58	Gm37655	predicted gene, 37655	9588	0.13
chr4_7567873_7568075	0.57	8430436N08Rik	RIKEN cDNA 8430436N08 gene	7286	0.32
chr4_141131586_141132124	0.57	Szrd1	SUZ RNA binding domain containing 1	7872	0.11
chr2_133511465_133511774	0.57	Bmp2	bone morphogenetic protein 2	40540	0.14
chr16_44133385_44133536	0.57	Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	5520	0.19
chr4_11762874_11763219	0.57	Cdh17	cadherin 17	4853	0.25
chr17_36894286_36894452	0.57	Trim31	tripartite motif-containing 31	3749	0.1
chr1_13660790_13660970	0.56	Lactb2	lactamase, beta 2	334	0.87
chr11_33203073_33203919	0.56	Tlx3	T cell leukemia, homeobox 3	93	0.88
chr8_22025214_22025365	0.56	Atp7b	ATPase, Cu++ transporting, beta polypeptide	34730	0.09
chr4_97102030_97102181	0.56	Gm27521	predicted gene, 27521	185085	0.03
chr12_12042917_12043068	0.56	Gm4294	predicted gene 4294	19947	0.2
chr2_153218461_153218795	0.56	Tspyl3	TSPY-like 3	6813	0.14
chr8_80055516_80055926	0.56	Hhip	Hedgehog-interacting protein	2285	0.32
chr3_52254073_52254404	0.56	Olfr1398-ps1	olfactory receptor 1398, pseudogene 1	7293	0.13
chr4_135874474_135874625	0.56	Pnrc2	proline-rich nuclear receptor coactivator 2	699	0.52
chr3_80787470_80787641	0.56	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	15024	0.25
chr2_129241136_129241588	0.55	Gm14024	predicted gene 14024	5014	0.11
chr7_72826599_72826750	0.55	Gm7693	predicted gene 7693	113053	0.06
chr1_67186231_67186382	0.55	Gm15668	predicted gene 15668	62894	0.11
chr7_126630054_126630205	0.55	Nupr1	nuclear protein transcription regulator 1	732	0.42
chr3_29732889_29733040	0.54	Gm37557	predicted gene, 37557	38320	0.19
chr13_62888125_62888325	0.54	Fbp1	fructose bisphosphatase 1	57	0.97
chr18_62211148_62211299	0.54	Gm9949	predicted gene 9949	31097	0.17
chr10_68090256_68090550	0.54	Arid5b	AT rich interactive domain 5B (MRF1-like)	46223	0.13
chrX_9222912_9223090	0.54	Lancl3	LanC lantibiotic synthetase component C-like 3 (bacterial)	23099	0.12
chr4_149445330_149446172	0.54	Rbp7	retinol binding protein 7, cellular	7673	0.11
chr11_98968695_98969422	0.53	Rara	retinoic acid receptor, alpha	8646	0.1
chr6_59162029_59162180	0.53	Gm43905	predicted gene, 43905	31149	0.17
chr8_3252706_3253021	0.53	Gm16180	predicted gene 16180	6841	0.21
chr3_20027390_20027663	0.53	Hps3	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1	7754	0.19
chr15_78413114_78413438	0.52	Mpst	mercaptopyruvate sulfurtransferase	3294	0.12
chr7_135581161_135581493	0.52	Ptpre	protein tyrosine phosphatase, receptor type, E	12061	0.17
chr17_94094392_94094543	0.52	Gm50004	predicted gene, 50004	37804	0.23
chr16_44177510_44177675	0.52	Usf3	upstream transcription factor family member 3	4195	0.23
chr19_10166053_10166204	0.52	Gm50359	predicted gene, 50359	10033	0.11
chr7_128289110_128289522	0.51	BC017158	cDNA sequence BC017158	611	0.44
chr1_131310511_131310734	0.51	Srgap2	SLIT-ROBO Rho GTPase activating protein 2	443	0.76
chrX_166627284_166627435	0.51	Gm15226	predicted gene 15226	5817	0.21
chr1_90481315_90481666	0.51	Gm28722	predicted gene 28722	26989	0.19
chr14_121214755_121214906	0.51	B930095G15Rik	RIKEN cDNA B930095G15 gene	33876	0.17
chr4_57954719_57954870	0.51	Txn1	thioredoxin 1	1617	0.4
chr5_97007576_97007868	0.51	Bmp2k	BMP2 inducible kinase	10033	0.14
chr7_84040262_84040413	0.51	Cemip	cell migration inducing protein, hyaluronan binding	46165	0.13
chr1_13655707_13655872	0.50	Lactb2	lactamase, beta 2	4757	0.19
chr13_31531222_31531375	0.50	Foxq1	forkhead box Q1	24836	0.13
chr19_11022451_11022797	0.50	Ms4a18	membrane-spanning 4-domains, subfamily A, member 18	4593	0.12
chr4_69594168_69594334	0.50	Gm11221	predicted gene 11221	97727	0.09
chr4_43964689_43964890	0.50	Glipr2	GLI pathogenesis-related 2	7097	0.14
chr18_13943186_13943337	0.50	Zfp521	zinc finger protein 521	28459	0.21
chr6_17554824_17555153	0.49	Met	met proto-oncogene	8015	0.24
chr18_19524329_19524663	0.49	Gm7720	predicted gene 7720	25897	0.27
chr5_145621725_145621876	0.49	Selenok-ps7	selenoprotein K, pseudogene 7	1567	0.33

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bbx

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.3	0.8	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.4	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.5	GO:0051031	tRNA transport(GO:0051031)
0.1	0.9	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.5	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.6	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.3	GO:0050904	diapedesis(GO:0050904)
0.1	0.4	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1	0.3	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	0.4	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.3	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	1.0	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.1	0.1	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.1	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.1	0.6	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.2	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.1	0.2	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1	0.3	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.1	0.2	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.1	0.2	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156)
0.1	0.3	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.2	GO:0043309	regulation of eosinophil degranulation(GO:0043309)
0.1	0.2	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1	0.1	GO:0038091	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1	0.3	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1	0.2	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.5	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.4	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.2	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.2	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	1.0	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.2	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.4	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.0	0.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.2	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.1	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.2	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0	0.2	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.1	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.2	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.2	GO:0006971	hypotonic response(GO:0006971)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.4	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:1901563	response to camptothecin(GO:1901563)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.3	GO:0031269	pseudopodium assembly(GO:0031269)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.6	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.3	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0070668	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.5	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.2	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.0	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0	0.0	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0002086	diaphragm contraction(GO:0002086)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.0	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	0.1	GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.6	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.1	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.3	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.3	GO:2000194	regulation of female gonad development(GO:2000194)
0.0	0.0	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.0	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0	0.1	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.0	GO:0009757	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.1	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.1	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0061032	visceral serous pericardium development(GO:0061032)
0.0	0.0	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.0	GO:0071608	macrophage inflammatory protein-1 alpha production(GO:0071608)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.7	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.4	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.0	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.1	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	1.0	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	0.0	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.0	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.0	0.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.0	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.0	GO:0045168	cell-cell signaling involved in cell fate commitment(GO:0045168)
0.0	0.2	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0070268	cornification(GO:0070268)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.1	GO:0015677	copper ion import(GO:0015677)
0.0	0.0	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.0	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.0	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.2	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.1	GO:2000637	positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.3	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.0	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.0	0.0	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.2	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.1	GO:0060631	regulation of meiosis I(GO:0060631)
0.0	0.1	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.3	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.1	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
0.0	0.1	GO:0051029	rRNA transport(GO:0051029)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.1	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.2	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.0	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.0	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.2	GO:0097006	regulation of plasma lipoprotein particle levels(GO:0097006)
0.0	0.0	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.0	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.1	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:1902224	ketone body metabolic process(GO:1902224)
0.0	0.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.0	GO:0021780	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0032512	regulation of protein phosphatase type 2B activity(GO:0032512)
0.0	0.0	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.0	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.0	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.0	GO:0006012	galactose metabolic process(GO:0006012)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.2	GO:0097443	sorting endosome(GO:0097443)
0.1	0.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.2	GO:0044393	microspike(GO:0044393)
0.1	0.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.2	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.4	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.4	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.2	GO:0089701	U2AF(GO:0089701)
0.0	0.9	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	0.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.0	0.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.4	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.2	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0000346	transcription export complex(GO:0000346)
0.0	0.0	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	1.0	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.0	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.2	0.8	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.5	GO:0009374	biotin binding(GO:0009374)
0.1	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	0.4	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.3	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.2	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	0.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.2	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.6	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.2	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.3	GO:0009378	four-way junction helicase activity(GO:0009378)
0.1	0.2	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1	0.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.3	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.3	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.5	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.3	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.2	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.0	0.9	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.3	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0019808	polyamine binding(GO:0019808)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.2	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.6	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.8	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.1	GO:0051380	beta-adrenergic receptor activity(GO:0004939) norepinephrine binding(GO:0051380)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004031	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.6	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.5	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.0	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.0	GO:0030351	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.0	GO:0032551	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.0	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.8	GO:0018423	protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
0.0	0.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0015254	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0019767	IgE receptor activity(GO:0019767)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.9	PID ATM PATHWAY	ATM pathway
0.0	1.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID EPO PATHWAY	EPO signaling pathway
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	0.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.6	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.7	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport