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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Esr2

Z-value: 11.51

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Transcription factors associated with Esr2

Gene Symbol	Gene ID	Gene Info
Esr2 Ensembl NCBI MGI UniProt	ENSMUSG00000021055.7	Esr2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Esr2	chr12_76196455_76197032	19484	0.134495	-0.67	2.6e-08	Click!
Esr2	chr12_76164612_76164763	3028	0.222714	-0.53	3.4e-05	Click!
Esr2	chr12_76195934_76196349	18882	0.135894	-0.07	6.1e-01	Click!

Activity of the Esr2 motif across conditions

Conditions sorted by the z-value of the Esr2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_14351950_14353283	370.39	Il3ra	interleukin 3 receptor, alpha chain	2995	0.15
chr14_14354416_14355184	124.90	Il3ra	interleukin 3 receptor, alpha chain	5179	0.12
chr8_84197696_84198961	94.16	Gm26887	predicted gene, 26887	661	0.38
chr5_112001700_112002600	58.87	Gm42488	predicted gene 42488	57915	0.13
chr5_137349031_137350198	57.95	Ephb4	Eph receptor B4	495	0.62
chr19_45016824_45017769	55.86	Lzts2	leucine zipper, putative tumor suppressor 2	799	0.44
chr3_65658208_65659857	52.20	Mir8120	microRNA 8120	256	0.89
chr2_165884402_165885933	51.36	Zmynd8	zinc finger, MYND-type containing 8	293	0.86
chr9_64793074_64793409	49.25	Dennd4a	DENN/MADD domain containing 4A	18099	0.18
chr10_127508848_127510720	48.65	Stac3	SH3 and cysteine rich domain 3	2559	0.15
chr7_17059591_17061170	48.22	4833404L02Rik	RIKEN cDNA 4833404L02 gene	1846	0.19
chr11_5168827_5169640	48.00	Emid1	EMI domain containing 1	16976	0.16
chr1_168287679_168288893	47.33	Gm37524	predicted gene, 37524	49385	0.16
chr7_142574309_142575453	46.82	H19	H19, imprinted maternally expressed transcript	1657	0.21
chr6_125095392_125097556	45.50	Chd4	chromodomain helicase DNA binding protein 4	95	0.84
chr8_70698268_70700333	45.07	Jund	jun D proto-oncogene	351	0.45
chr18_3005171_3005609	43.16	Gm50072	predicted gene, 50072	10518	0.21
chr8_120549369_120550473	42.70	Mir7687	microRNA 7687	11225	0.1
chr2_121036499_121036885	42.50	Epb42	erythrocyte membrane protein band 4.2	11	0.96
chr8_84979246_84980613	41.39	Junb	jun B proto-oncogene	1211	0.19
chr11_116616197_116616677	41.38	Rhbdf2	rhomboid 5 homolog 2	7763	0.1
chr11_120353462_120354038	41.30	0610009L18Rik	RIKEN cDNA 0610009L18 gene	5072	0.09
chr11_32296772_32297209	41.24	Hba-a2	hemoglobin alpha, adult chain 2	362	0.77
chr5_140647773_140649317	40.76	Ttyh3	tweety family member 3	452	0.77
chr2_174347204_174348264	40.61	Gm20721	predicted gene, 20721	1022	0.44
chr1_191641396_191641769	40.50	Gm37349	predicted gene, 37349	43935	0.11
chrX_51204673_51205680	40.45	Mbnl3	muscleblind like splicing factor 3	656	0.65
chr5_115436438_115437458	39.55	4930430O22Rik	RIKEN cDNA 4930430O22 gene	304	0.74
chr5_139796762_139798525	39.29	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	129	0.94
chr11_97435561_97436362	39.23	Arhgap23	Rho GTPase activating protein 23	324	0.87
chr5_137530580_137532081	39.22	Gnb2	guanine nucleotide binding protein (G protein), beta 2	33	0.9
chr2_26139656_26141133	39.14	Tmem250-ps	transmembrane protein 250, pseudogene	127	0.93
chr5_140204146_140204297	38.74	Gm16120	predicted gene 16120	3164	0.23
chr4_132075006_132075723	38.27	Epb41	erythrocyte membrane protein band 4.1	43	0.91
chr7_100500401_100501097	38.05	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	2403	0.14
chr1_86525613_86527056	37.82	Ptma	prothymosin alpha	392	0.81
chr9_61370339_61371660	37.74	Gm10655	predicted gene 10655	628	0.63
chr15_82184037_82184673	37.56	Gm49502	predicted gene, 49502	1161	0.29
chr16_95990397_95991380	37.55	Psmg1	proteasome (prosome, macropain) assembly chaperone 1	2	0.97
chr11_30648868_30649937	37.45	Acyp2	acylphosphatase 2, muscle type	185	0.95
chr6_97204968_97206158	37.35	Uba3	ubiquitin-like modifier activating enzyme 3	2	0.97
chr11_31830043_31830943	37.30	Gm12107	predicted gene 12107	2167	0.31
chr14_8286642_8286923	37.28	Fam107a	family with sequence similarity 107, member A	22995	0.16
chr5_140439026_140439687	37.15	Eif3b	eukaryotic translation initiation factor 3, subunit B	586	0.63
chr2_158305932_158306715	37.03	Lbp	lipopolysaccharide binding protein	170	0.92
chr2_155604522_155604830	36.72	Myh7b	myosin, heavy chain 7B, cardiac muscle, beta	6536	0.08
chr8_90907824_90909226	36.49	Chd9	chromodomain helicase DNA binding protein 9	89	0.52
chr15_88875576_88876323	36.44	Pim3	proviral integration site 3	11029	0.13
chr5_109557850_109558797	36.43	Crlf2	cytokine receptor-like factor 2	613	0.67
chr5_91292941_91293393	36.37	Gm19619	predicted gene, 19619	9746	0.24
chr11_102375203_102375512	36.33	Bloodlinc	Bloodlinc, erythroid developmental long intergenic non-protein coding transcript	1663	0.21
chr8_122329580_122330425	36.14	Zfpm1	zinc finger protein, multitype 1	3696	0.15
chr11_87126714_87127907	35.87	Trim37	tripartite motif-containing 37	5	0.84
chr2_152636359_152637068	35.78	Rem1	rad and gem related GTP binding protein 1	3746	0.1
chr9_103007679_103008651	35.22	Slco2a1	solute carrier organic anion transporter family, member 2a1	11	0.97
chr11_11684707_11686418	35.18	Gm11999	predicted gene 11999	162	0.73
chr11_117204633_117204995	35.11	Septin9	septin 9	5153	0.19
chrX_142680720_142682167	35.10	Tmem164	transmembrane protein 164	25	0.98
chr11_74896307_74898160	34.92	Sgsm2	small G protein signaling modulator 2	173	0.84
chrY_90771840_90772811	34.84	Gm47283	predicted gene, 47283	12413	0.17
chr2_31464551_31464797	34.63	Ass1	argininosuccinate synthetase 1	5533	0.2
chr8_120295274_120295807	34.58	Gse1	genetic suppressor element 1, coiled-coil protein	67084	0.09
chr15_86058286_86059442	34.54	Gramd4	GRAM domain containing 4	8	0.98
chr7_16046417_16047443	34.53	Bicra	BRD4 interacting chromatin remodeling complex associated protein	991	0.44
chr6_124919273_124920636	34.23	Ptms	parathymosin	149	0.88
chr8_68276160_68277629	34.20	Sh2d4a	SH2 domain containing 4A	327	0.89
chr16_11423409_11423900	34.15	Snx29	sorting nexin 29	2946	0.31
chrX_94366585_94367598	34.15	Apoo	apolipoprotein O	26	0.81
chr15_77882572_77883557	33.92	Txn2	thioredoxin 2	32636	0.11
chr11_32283952_32284215	33.37	Hba-a1	hemoglobin alpha, adult chain 1	272	0.83
chr17_25127091_25127504	33.20	Clcn7	chloride channel, voltage-sensitive 7	6094	0.1
chr6_52163698_52164573	33.08	Hoxa2	homeobox A2	696	0.33
chr10_127062800_127064205	32.98	Cdk4	cyclin-dependent kinase 4	32	0.93
chr7_126271797_126273090	32.72	Sbk1	SH3-binding kinase 1	176	0.92
chr1_36539232_36539550	32.68	Gm42417	predicted gene, 42417	33	0.94
chr12_101028530_101029714	32.50	Ccdc88c	coiled-coil domain containing 88C	66	0.95
chr5_146687980_146688258	32.34	4930573C15Rik	RIKEN cDNA 4930573C15 gene	18503	0.16
chr9_63757305_63758776	32.31	Smad3	SMAD family member 3	46	0.98
chr3_103171228_103172264	32.20	Bcas2	breast carcinoma amplified sequence 2	3	0.97
chr9_114752784_114753499	32.02	Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	21968	0.13
chr1_85163919_85164982	31.69	Gm6264	predicted gene 6264	3587	0.13
chr17_47909349_47909983	31.55	Gm15556	predicted gene 15556	12712	0.13
chr13_34344501_34346084	31.48	Slc22a23	solute carrier family 22, member 23	110	0.97
chr11_105125823_105126961	31.46	Mettl2	methyltransferase like 2	33	0.97
chr15_85669900_85671551	31.45	Lncppara	long noncoding RNA near Ppara	17109	0.13
chr11_19924323_19926342	31.42	Spred2	sprouty-related EVH1 domain containing 2	890	0.71
chr7_28179836_28180482	31.33	Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	107	0.93
chr5_119337927_119338125	31.27	n-R5s175	nuclear encoded rRNA 5S 175	40781	0.19
chr15_83375189_83375572	31.19	1700001L05Rik	RIKEN cDNA 1700001L05 gene	8098	0.14
chr11_75443808_75444173	31.15	Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	4399	0.09
chr19_5845343_5846183	30.99	Frmd8os	FERM domain containing 8, opposite strand	140	0.66
chr11_48873308_48874023	30.87	Irgm1	immunity-related GTPase family M member 1	1982	0.19
chr2_173032812_173033942	30.80	Gm14453	predicted gene 14453	1203	0.38
chr18_65025526_65026378	30.74	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	150	0.97
chr12_79557815_79558259	30.72	Rad51b	RAD51 paralog B	230684	0.02
chr11_78074361_78074827	30.47	Mir451b	microRNA 451b	1353	0.16
chr13_37666246_37666836	30.43	AI463229	expressed sequence AI463229	1	0.96
chr10_94931912_94932258	30.41	Plxnc1	plexin C1	9428	0.21
chr2_11425648_11426122	30.27	Gm13296	predicted gene 13296	5661	0.12
chr11_87749523_87749886	30.21	Mir142hg	Mir142 host gene (non-protein coding)	5873	0.09
chr9_121426081_121426568	30.20	Trak1	trafficking protein, kinesin binding 1	10349	0.19
chr15_102017591_102018334	29.94	Krt18	keratin 18	10218	0.11
chr10_62980040_62980767	29.91	Rufy2	RUN and FYVE domain-containing 2	110	0.93
chr9_65826224_65827697	29.86	Zfp609	zinc finger protein 609	604	0.65
chr4_134760766_134761128	29.83	Ldlrap1	low density lipoprotein receptor adaptor protein 1	7077	0.2
chr12_80103423_80104027	29.79	Zfp36l1	zinc finger protein 36, C3H type-like 1	9269	0.12
chr4_133552955_133553552	29.75	Nr0b2	nuclear receptor subfamily 0, group B, member 2	123	0.92
chr6_72097140_72098281	29.70	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	47	0.96
chr3_100488535_100489982	29.70	Tent5c	terminal nucleotidyltransferase 5C	60	0.85
chr5_148740927_148741236	29.64	2210417A02Rik	RIKEN cDNA 2210417A02 gene	759	0.59
chr6_30146983_30147411	29.61	Mir182	microRNA 182	18795	0.12
chr17_70850487_70852089	29.59	Tgif1	TGFB-induced factor homeobox 1	81	0.94
chr11_32256536_32256847	29.52	Nprl3	nitrogen permease regulator-like 3	278	0.84
chr7_141364719_141364989	29.51	B230206H07Rik	RIKEN cDNA B230206H07 gene	228	0.82
chr1_24613351_24614205	29.47	Gm28437	predicted gene 28437	193	0.69
chr4_119028258_119028409	29.47	Gm12862	predicted gene 12862	27848	0.08
chr11_97434692_97435371	29.45	Arhgap23	Rho GTPase activating protein 23	1254	0.42
chrX_160426520_160426808	29.43	Adgrg2	adhesion G protein-coupled receptor G2	628	0.76
chr4_144949407_144950626	29.12	Gm38074	predicted gene, 38074	8832	0.2
chr2_69897352_69898558	29.06	Ubr3	ubiquitin protein ligase E3 component n-recognin 3	652	0.6
chr10_77110050_77110376	29.02	Col18a1	collagen, type XVIII, alpha 1	3492	0.22
chrX_169997850_169998483	28.89	Gm15247	predicted gene 15247	11227	0.14
chr4_133557474_133557769	28.89	Gm23158	predicted gene, 23158	1328	0.26
chr4_63236307_63236627	28.67	Col27a1	collagen, type XXVII, alpha 1	2181	0.28
chr11_74837693_74838808	28.54	Mnt	max binding protein	782	0.52
chr5_125389942_125390330	28.44	Ubc	ubiquitin C	66	0.92
chr5_124439753_124440600	28.38	Kmt5a	lysine methyltransferase 5A	191	0.89
chr16_76319178_76320114	28.24	Nrip1	nuclear receptor interacting protein 1	4012	0.29
chr7_99837519_99837978	28.18	Neu3	neuraminidase 3	9331	0.12
chr9_111057150_111057866	28.08	Ccrl2	chemokine (C-C motif) receptor-like 2	11	0.95
chr5_143731658_143732384	28.06	Usp42	ubiquitin specific peptidase 42	259	0.91
chr11_100938783_100940230	28.02	Stat3	signal transducer and activator of transcription 3	27	0.97
chr3_89390311_89391266	28.01	Gm15417	predicted gene 15417	1062	0.22
chr1_189695352_189695549	28.00	Cenpf	centromere protein F	7364	0.18
chr15_79690079_79691459	27.99	Gtpbp1	GTP binding protein 1	76	0.92
chr11_106324879_106325283	27.90	Cd79b	CD79B antigen	10319	0.11
chr19_7240431_7241403	27.89	Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	117	0.93
chr19_61057665_61057910	27.83	Gm22520	predicted gene, 22520	44242	0.12
chr6_90712861_90713488	27.83	Iqsec1	IQ motif and Sec7 domain 1	3355	0.21
chr4_137480764_137481043	27.75	Hspg2	perlecan (heparan sulfate proteoglycan 2)	12100	0.13
chr11_115898961_115899323	27.64	Smim5	small integral membrane protein 5	824	0.4
chr3_30507827_30509444	27.54	Mecom	MDS1 and EVI1 complex locus	852	0.52
chr12_111353338_111354089	27.48	Cdc42bpb	CDC42 binding protein kinase beta	23906	0.13
chr1_86527639_86529135	27.47	Ptma	prothymosin alpha	1580	0.31
chr8_122317511_122318419	27.41	Zfpm1	zinc finger protein, multitype 1	10645	0.13
chrX_42067696_42069057	27.38	Xiap	X-linked inhibitor of apoptosis	22	0.98
chr2_168154178_168154991	27.36	E130018N17Rik	RIKEN cDNA E130018N17 gene	71	0.93
chr11_45854715_45855015	27.36	Clint1	clathrin interactor 1	2901	0.21
chr19_41482494_41483686	27.28	Lcor	ligand dependent nuclear receptor corepressor	61	0.98
chr11_75462325_75462847	27.11	Tlcd2	TLC domain containing 2	871	0.25
chr4_154122202_154122744	27.08	Trp73	transformation related protein 73	5868	0.12
chr10_121569006_121569830	27.02	Tbk1	TANK-binding kinase 1	937	0.48
chr7_14525378_14525601	26.99	Obox4-ps2	oocyte specific homeobox 4, pseudogene 2	4577	0.13
chr7_103853072_103853426	26.99	Hbb-y	hemoglobin Y, beta-like embryonic chain	33	0.92
chr18_82474598_82476191	26.91	Mbp	myelin basic protein	24	0.98
chr11_98941353_98942362	26.83	Rara	retinoic acid receptor, alpha	2145	0.18
chr3_104674273_104674621	26.79	Gm29560	predicted gene 29560	4437	0.11
chr9_46012271_46012911	26.77	Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	99	0.68
chr6_72391207_72391516	26.75	Vamp8	vesicle-associated membrane protein 8	658	0.53
chr15_76697423_76698657	26.67	Gpt	glutamic pyruvic transaminase, soluble	22	0.93
chr10_80819581_80819742	26.66	Jsrp1	junctional sarcoplasmic reticulum protein 1	6163	0.07
chr11_70092126_70092295	26.61	Asgr2	asialoglycoprotein receptor 2	434	0.69
chr7_4739300_4740219	26.59	Kmt5c	lysine methyltransferase 5C	356	0.63
chr9_50856310_50857724	26.55	Ppp2r1b	protein phosphatase 2, regulatory subunit A, beta	38	0.97
chr18_32543067_32543441	26.55	Gypc	glycophorin C	7836	0.2
chr15_76199374_76200434	26.54	Plec	plectin	69	0.94
chr8_122551277_122551909	26.52	Piezo1	piezo-type mechanosensitive ion channel component 1	264	0.83
chr8_123181510_123181661	26.46	Dpep1	dipeptidase 1	4657	0.08
chr10_81627030_81627544	26.36	Sirt6	sirtuin 6	30	0.93
chr12_111442215_111442766	26.35	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	21	0.96
chr2_155604966_155605247	26.26	Myh7b	myosin, heavy chain 7B, cardiac muscle, beta	6106	0.08
chr2_156296379_156296596	25.90	Phf20	PHD finger protein 20	82	0.94
chr10_80576603_80578409	25.88	Klf16	Kruppel-like factor 16	185	0.86
chr15_98608664_98610204	25.81	Adcy6	adenylate cyclase 6	598	0.55
chr7_132772857_132773208	25.81	Fam53b	family with sequence similarity 53, member B	3884	0.24
chr1_80408527_80409167	25.80	Gm6189	predicted gene 6189	23662	0.13
chr5_113220320_113221537	25.75	2900026A02Rik	RIKEN cDNA 2900026A02 gene	308	0.86
chr11_101063294_101064479	25.56	Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)	6126	0.09
chr11_75925837_75926169	25.52	Rph3al	rabphilin 3A-like (without C2 domains)	112	0.97
chr13_47250640_47250987	25.49	Rnf144b	ring finger protein 144B	56988	0.11
chr8_123980624_123981024	25.48	Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	2298	0.17
chr10_80160842_80161483	25.47	Cirbp	cold inducible RNA binding protein	4823	0.09
chr17_71268038_71268559	25.47	Emilin2	elastin microfibril interfacer 2	299	0.88
chr2_167039436_167039757	25.39	Znfx1	zinc finger, NFX1-type containing 1	3899	0.11
chr7_5060805_5061447	25.38	Gm45133	predicted gene 45133	923	0.22
chr6_57767497_57767835	25.23	Vopp1	vesicular, overexpressed in cancer, prosurvival protein 1	56974	0.07
chr7_145043442_145043822	25.18	Ccnd1	cyclin D1	103707	0.05
chr5_21141044_21141247	25.10	Gm42660	predicted gene 42660	10069	0.13
chr10_80963206_80963454	25.09	Gm3828	predicted gene 3828	8620	0.1
chr14_64158929_64159285	25.08	9630015K15Rik	RIKEN cDNA 9630015K15 gene	42793	0.11
chr5_146691845_146692708	25.06	4930573C15Rik	RIKEN cDNA 4930573C15 gene	14346	0.17
chr14_14353319_14353777	25.03	Il3ra	interleukin 3 receptor, alpha chain	3927	0.13
chr5_139388991_139389572	24.97	Gpr146	G protein-coupled receptor 146	504	0.68
chr16_23057965_23058373	24.97	Kng1	kininogen 1	81	0.92
chr8_126497512_126498658	24.94	Gm6091	predicted pseudogene 6091	21673	0.18
chr11_75651168_75652336	24.93	Myo1c	myosin IC	242	0.88
chr12_80084359_80084746	24.93	Gm36660	predicted gene, 36660	3118	0.18
chr10_127288807_127289691	24.88	Mbd6	methyl-CpG binding domain protein 6	231	0.7
chr7_116286230_116286742	24.87	Gm44867	predicted gene 44867	3601	0.19
chr7_28597227_28598470	24.86	Pak4	p21 (RAC1) activated kinase 4	238	0.53

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Esr2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
32.0	32.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
31.9	95.6	GO:0060375	regulation of mast cell differentiation(GO:0060375)
30.6	91.9	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
28.2	56.3	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
25.9	103.4	GO:0031581	hemidesmosome assembly(GO:0031581)
25.2	100.7	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
22.3	66.9	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
20.6	61.9	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
20.6	61.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
20.0	100.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
19.9	59.8	GO:0002432	granuloma formation(GO:0002432)
19.5	39.0	GO:0006741	NADP biosynthetic process(GO:0006741)
19.5	39.0	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
19.4	77.5	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
18.9	56.8	GO:0048769	sarcomerogenesis(GO:0048769)
18.8	56.3	GO:0036394	amylase secretion(GO:0036394)
18.7	37.4	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
18.3	18.3	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
18.2	54.7	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
18.1	36.2	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
17.8	53.5	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
17.8	53.5	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
17.6	17.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
17.1	51.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
17.1	51.3	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
17.1	51.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
17.0	33.9	GO:0071462	cellular response to water stimulus(GO:0071462)
16.6	49.8	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
16.5	49.6	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
16.2	64.8	GO:0006114	glycerol biosynthetic process(GO:0006114)
16.1	48.4	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
16.0	48.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
15.8	15.8	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
15.8	47.3	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
15.7	47.2	GO:0016554	cytidine to uridine editing(GO:0016554)
15.7	62.7	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
15.6	93.5	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534)
15.6	46.7	GO:0002086	diaphragm contraction(GO:0002086)
15.5	46.5	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
15.3	46.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
15.3	15.3	GO:0070384	Harderian gland development(GO:0070384)
15.2	60.8	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
15.1	45.4	GO:0015793	glycerol transport(GO:0015793)
15.1	75.3	GO:0070836	caveola assembly(GO:0070836)
15.0	75.2	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
15.0	60.1	GO:0070627	ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460)
14.9	74.6	GO:0015722	canalicular bile acid transport(GO:0015722)
14.9	44.8	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
14.8	88.5	GO:0015671	oxygen transport(GO:0015671)
14.6	14.6	GO:0043096	purine nucleobase salvage(GO:0043096)
14.1	56.5	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
14.1	14.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
14.1	42.3	GO:0003166	bundle of His development(GO:0003166)
14.1	42.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
14.0	56.0	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
14.0	41.9	GO:2001225	regulation of chloride transport(GO:2001225)
13.9	41.7	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
13.9	41.6	GO:2000823	regulation of androgen receptor activity(GO:2000823)
13.9	55.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
13.8	41.5	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
13.8	41.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
13.7	54.8	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
13.7	54.7	GO:0023021	termination of signal transduction(GO:0023021)
13.7	27.3	GO:0050904	diapedesis(GO:0050904)
13.5	40.6	GO:0051599	response to hydrostatic pressure(GO:0051599)
13.5	54.1	GO:0008228	opsonization(GO:0008228)
13.5	175.1	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
13.4	67.1	GO:0072675	osteoclast fusion(GO:0072675)
13.4	40.3	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
13.4	13.4	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
13.4	53.6	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
13.3	40.0	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
13.3	39.9	GO:0060931	sinoatrial node cell development(GO:0060931)
13.3	26.5	GO:0009436	glyoxylate catabolic process(GO:0009436)
13.2	53.0	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
13.1	52.6	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
13.1	39.3	GO:0002337	B-1a B cell differentiation(GO:0002337)
13.1	65.4	GO:0075525	viral translational termination-reinitiation(GO:0075525)
13.1	65.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
12.9	51.6	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
12.9	12.9	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
12.8	25.7	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
12.8	38.5	GO:0033668	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
12.8	64.0	GO:0010815	bradykinin catabolic process(GO:0010815)
12.8	38.4	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
12.8	25.6	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
12.8	12.8	GO:0019344	cysteine biosynthetic process(GO:0019344)
12.6	25.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
12.6	37.8	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
12.4	37.2	GO:0034499	late endosome to Golgi transport(GO:0034499)
12.4	37.2	GO:0018992	germ-line sex determination(GO:0018992)
12.4	296.4	GO:0048821	erythrocyte development(GO:0048821)
12.3	49.4	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
12.3	36.9	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
12.3	24.6	GO:0061511	centriole elongation(GO:0061511)
12.2	36.5	GO:0000087	mitotic M phase(GO:0000087)
12.2	24.3	GO:0001543	ovarian follicle rupture(GO:0001543)
12.0	48.2	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
11.9	47.7	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
11.9	59.6	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
11.9	35.6	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
11.9	59.3	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
11.8	59.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
11.8	47.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
11.8	35.3	GO:0042908	xenobiotic transport(GO:0042908)
11.8	70.5	GO:0010992	ubiquitin homeostasis(GO:0010992)
11.7	129.2	GO:0060263	regulation of respiratory burst(GO:0060263)
11.7	11.7	GO:1902930	regulation of alcohol biosynthetic process(GO:1902930)
11.7	11.7	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
11.7	23.4	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
11.7	35.1	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
11.7	46.7	GO:0001887	selenium compound metabolic process(GO:0001887)
11.6	11.6	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
11.5	23.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
11.5	34.5	GO:0032782	bile acid secretion(GO:0032782)
11.5	91.8	GO:0097062	dendritic spine maintenance(GO:0097062)
11.5	22.9	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
11.4	34.2	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
11.4	34.2	GO:0003176	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
11.4	56.9	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
11.4	45.5	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
11.3	34.0	GO:0003032	detection of oxygen(GO:0003032)
11.3	33.8	GO:0006481	C-terminal protein methylation(GO:0006481)
11.3	90.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
11.2	33.7	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
11.2	56.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
11.1	22.3	GO:0001969	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
11.1	33.3	GO:0070889	platelet alpha granule organization(GO:0070889)
11.1	44.4	GO:0097039	protein linear polyubiquitination(GO:0097039)
11.1	11.1	GO:0071824	protein-DNA complex subunit organization(GO:0071824)
11.1	66.5	GO:0006526	arginine biosynthetic process(GO:0006526)
11.0	66.0	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
11.0	11.0	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
11.0	55.0	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
11.0	77.0	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
10.9	10.9	GO:1902302	regulation of potassium ion export(GO:1902302)
10.8	32.5	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
10.8	249.3	GO:0033014	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
10.8	10.8	GO:0007091	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
10.8	43.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
10.6	21.2	GO:0044557	relaxation of smooth muscle(GO:0044557)
10.6	10.6	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
10.5	21.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
10.5	31.6	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
10.5	94.5	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
10.5	41.9	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
10.5	41.8	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
10.4	83.2	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
10.4	20.7	GO:0045900	negative regulation of translational elongation(GO:0045900)
10.3	51.4	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
10.3	20.5	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
10.2	40.9	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
10.2	10.2	GO:2000589	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
10.1	30.4	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
10.1	10.1	GO:0006549	isoleucine metabolic process(GO:0006549)
10.1	30.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
10.1	40.3	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
10.1	30.2	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
10.1	30.2	GO:0048388	endosomal lumen acidification(GO:0048388)
10.0	30.1	GO:0015886	heme transport(GO:0015886)
10.0	40.2	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
10.0	40.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
10.0	30.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
10.0	10.0	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
10.0	19.9	GO:1990705	cholangiocyte proliferation(GO:1990705)
9.9	29.8	GO:0036166	phenotypic switching(GO:0036166)
9.9	39.7	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
9.9	9.9	GO:0071316	cellular response to nicotine(GO:0071316)
9.9	19.8	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
9.9	69.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
9.9	29.6	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
9.8	29.5	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
9.8	49.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
9.8	29.5	GO:0019371	cyclooxygenase pathway(GO:0019371)
9.8	88.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
9.8	19.6	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
9.8	19.6	GO:2000644	regulation of receptor catabolic process(GO:2000644)
9.8	39.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
9.8	107.4	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
9.7	9.7	GO:0048368	lateral mesoderm development(GO:0048368)
9.7	29.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
9.7	19.4	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
9.7	29.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
9.7	38.9	GO:0007296	vitellogenesis(GO:0007296)
9.7	19.4	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
9.7	38.7	GO:0043622	cortical microtubule organization(GO:0043622)
9.7	19.3	GO:1900221	regulation of beta-amyloid clearance(GO:1900221)
9.6	38.2	GO:0006116	NADH oxidation(GO:0006116)
9.6	47.8	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
9.5	56.9	GO:0043173	nucleotide salvage(GO:0043173)
9.5	9.5	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
9.5	85.1	GO:0045332	phospholipid translocation(GO:0045332)
9.4	37.8	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
9.4	9.4	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
9.4	84.9	GO:0006855	drug transmembrane transport(GO:0006855)
9.4	18.9	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
9.4	9.4	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
9.4	37.6	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
9.4	56.3	GO:0008343	adult feeding behavior(GO:0008343)
9.4	46.9	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
9.3	37.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
9.3	83.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
9.3	9.3	GO:0042756	drinking behavior(GO:0042756)
9.3	27.8	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
9.2	27.7	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
9.2	27.7	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
9.2	18.4	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
9.2	27.6	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
9.2	9.2	GO:0071332	cellular response to fructose stimulus(GO:0071332)
9.1	36.5	GO:0061113	pancreas morphogenesis(GO:0061113)
9.1	18.2	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
9.1	27.4	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
9.1	36.4	GO:0036302	atrioventricular canal development(GO:0036302)
9.1	36.4	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
9.1	36.3	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
9.0	63.3	GO:0015825	L-serine transport(GO:0015825)
9.0	27.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
9.0	27.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
9.0	54.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
9.0	9.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
8.9	35.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
8.9	160.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
8.9	53.4	GO:0046874	quinolinate metabolic process(GO:0046874)
8.9	17.8	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
8.9	8.9	GO:0018214	protein carboxylation(GO:0018214)
8.9	97.7	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
8.9	17.7	GO:1901678	iron coordination entity transport(GO:1901678)
8.8	35.2	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
8.8	61.3	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
8.7	26.2	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
8.7	34.8	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
8.7	34.8	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
8.7	78.3	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
8.7	8.7	GO:0010624	regulation of Schwann cell proliferation(GO:0010624)
8.7	52.0	GO:0015871	choline transport(GO:0015871)
8.7	52.0	GO:0046060	dATP metabolic process(GO:0046060)
8.7	26.0	GO:1902075	cellular response to salt(GO:1902075)
8.6	95.1	GO:0042730	fibrinolysis(GO:0042730)
8.6	8.6	GO:0002159	desmosome assembly(GO:0002159)
8.6	25.9	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
8.6	17.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
8.6	17.2	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
8.6	34.4	GO:0048194	Golgi vesicle budding(GO:0048194)
8.6	77.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
8.6	25.7	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
8.5	34.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
8.5	51.1	GO:0006004	fucose metabolic process(GO:0006004)
8.5	212.8	GO:0014823	response to activity(GO:0014823)
8.5	42.5	GO:0002457	T cell antigen processing and presentation(GO:0002457)
8.5	33.9	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
8.5	25.4	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
8.5	8.5	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
8.5	16.9	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
8.4	8.4	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
8.4	16.8	GO:0043379	memory T cell differentiation(GO:0043379)
8.4	8.4	GO:0010958	regulation of amino acid import(GO:0010958)
8.4	50.3	GO:0044351	macropinocytosis(GO:0044351)
8.4	33.5	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
8.4	16.7	GO:1904059	regulation of locomotor rhythm(GO:1904059)
8.4	16.7	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
8.4	33.4	GO:0042866	pyruvate biosynthetic process(GO:0042866)
8.3	25.0	GO:0034729	histone H3-K79 methylation(GO:0034729)
8.3	8.3	GO:1903525	regulation of membrane tubulation(GO:1903525)
8.3	16.7	GO:0035754	B cell chemotaxis(GO:0035754)
8.3	41.6	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
8.3	8.3	GO:0033129	positive regulation of histone phosphorylation(GO:0033129)
8.3	41.5	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
8.3	33.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
8.3	8.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
8.3	33.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
8.2	8.2	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
8.2	32.8	GO:0097581	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
8.2	73.8	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
8.2	24.6	GO:2000574	regulation of microtubule motor activity(GO:2000574)
8.2	81.7	GO:0034063	stress granule assembly(GO:0034063)
8.2	24.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
8.1	8.1	GO:0097167	circadian regulation of translation(GO:0097167)
8.1	32.4	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
8.1	24.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
8.1	24.2	GO:0090230	regulation of centromere complex assembly(GO:0090230)
8.1	16.1	GO:0006098	pentose-phosphate shunt(GO:0006098)
8.1	24.2	GO:0032439	endosome localization(GO:0032439)
8.0	8.0	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
8.0	8.0	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
8.0	56.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
8.0	8.0	GO:0097503	sialylation(GO:0097503)
8.0	39.9	GO:0006907	pinocytosis(GO:0006907)
8.0	23.9	GO:1904690	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
8.0	23.9	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
7.9	7.9	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
7.9	15.9	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
7.9	31.8	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
7.9	15.8	GO:1903429	regulation of cell maturation(GO:1903429)
7.9	23.7	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
7.9	7.9	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
7.9	7.9	GO:1903059	regulation of protein lipidation(GO:1903059)
7.9	31.5	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
7.9	23.6	GO:0051197	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
7.9	47.2	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
7.9	15.7	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
7.8	23.5	GO:0008050	female courtship behavior(GO:0008050)
7.8	54.9	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
7.8	94.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
7.8	78.3	GO:0070828	heterochromatin organization(GO:0070828)
7.8	54.8	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
7.8	15.6	GO:0044793	negative regulation by host of viral process(GO:0044793)
7.8	78.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
7.8	23.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
7.8	38.9	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
7.8	23.3	GO:0060056	mammary gland involution(GO:0060056)
7.7	7.7	GO:0009437	carnitine metabolic process(GO:0009437)
7.7	62.0	GO:0050872	white fat cell differentiation(GO:0050872)
7.7	38.7	GO:0018101	protein citrullination(GO:0018101)
7.7	30.9	GO:1904354	negative regulation of telomere capping(GO:1904354)
7.7	38.5	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
7.7	7.7	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
7.6	22.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
7.6	7.6	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
7.6	7.6	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
7.6	45.6	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
7.6	45.6	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
7.6	15.2	GO:0046185	aldehyde catabolic process(GO:0046185)
7.5	15.1	GO:0010847	regulation of chromatin assembly(GO:0010847)
7.5	75.4	GO:0030212	hyaluronan metabolic process(GO:0030212)
7.5	7.5	GO:0043091	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
7.5	60.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
7.5	67.7	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
7.5	30.0	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.5	45.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
7.5	52.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
7.5	29.9	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
7.4	14.9	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
7.4	81.8	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
7.4	14.8	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
7.4	111.1	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
7.4	7.4	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
7.4	22.1	GO:0015705	iodide transport(GO:0015705)
7.4	73.8	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
7.4	73.8	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
7.4	7.4	GO:0036438	maintenance of lens transparency(GO:0036438)
7.3	22.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
7.3	73.3	GO:0007035	vacuolar acidification(GO:0007035)
7.3	29.3	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
7.3	29.2	GO:0019532	oxalate transport(GO:0019532)
7.3	7.3	GO:1903012	positive regulation of bone development(GO:1903012)
7.3	14.6	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
7.3	21.9	GO:0001712	ectodermal cell fate commitment(GO:0001712)
7.3	43.8	GO:0010889	regulation of sequestering of triglyceride(GO:0010889)
7.3	51.0	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
7.3	87.4	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
7.3	21.8	GO:0006344	maintenance of chromatin silencing(GO:0006344)
7.3	21.8	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
7.3	29.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
7.3	21.8	GO:0046104	thymidine metabolic process(GO:0046104)
7.2	29.0	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
7.2	43.5	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
7.2	21.6	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
7.2	14.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
7.2	21.6	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
7.2	14.4	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
7.2	7.2	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
7.2	100.6	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
7.2	43.1	GO:0030953	astral microtubule organization(GO:0030953)
7.1	57.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
7.1	14.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
7.1	21.4	GO:0046340	diacylglycerol catabolic process(GO:0046340)
7.1	42.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
7.1	7.1	GO:0071288	cellular response to mercury ion(GO:0071288)
7.1	35.5	GO:0071763	nuclear membrane organization(GO:0071763)
7.1	21.3	GO:0018094	protein polyglycylation(GO:0018094)
7.1	7.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
7.1	14.2	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
7.1	63.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
7.1	14.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
7.0	14.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
7.0	7.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
7.0	28.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
7.0	42.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
7.0	7.0	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
7.0	21.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
7.0	28.1	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
7.0	7.0	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
7.0	7.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
7.0	34.8	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
7.0	41.7	GO:0032462	regulation of protein homooligomerization(GO:0032462)
6.9	27.8	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
6.9	6.9	GO:0035995	detection of muscle stretch(GO:0035995)
6.9	20.8	GO:0001866	NK T cell proliferation(GO:0001866)
6.9	13.8	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
6.9	27.6	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
6.9	27.6	GO:0046600	negative regulation of centriole replication(GO:0046600)
6.9	20.6	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
6.9	13.7	GO:0006573	valine metabolic process(GO:0006573)
6.9	6.9	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
6.9	20.6	GO:0048102	autophagic cell death(GO:0048102)
6.8	6.8	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
6.8	20.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
6.8	20.5	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
6.8	13.6	GO:0051088	monocyte activation(GO:0042117) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
6.8	34.1	GO:1901341	positive regulation of store-operated calcium channel activity(GO:1901341)
6.8	88.5	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
6.8	6.8	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
6.8	13.6	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
6.8	20.4	GO:0060480	lung goblet cell differentiation(GO:0060480)
6.8	13.6	GO:0061687	detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
6.8	6.8	GO:0048807	female genitalia morphogenesis(GO:0048807)
6.7	20.2	GO:0046292	formaldehyde metabolic process(GO:0046292)
6.7	20.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
6.7	6.7	GO:0046685	response to arsenic-containing substance(GO:0046685)
6.7	6.7	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
6.7	46.8	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
6.7	60.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
6.7	53.3	GO:0071361	cellular response to ethanol(GO:0071361)
6.7	13.3	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
6.6	26.6	GO:0031584	activation of phospholipase D activity(GO:0031584)
6.6	6.6	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176)
6.6	53.0	GO:0043486	histone exchange(GO:0043486)
6.6	13.2	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
6.6	65.8	GO:0018904	ether metabolic process(GO:0018904)
6.6	13.1	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
6.6	19.7	GO:0006068	ethanol catabolic process(GO:0006068)
6.6	13.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
6.6	19.7	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
6.5	19.6	GO:0030916	otic vesicle formation(GO:0030916)
6.5	39.2	GO:0050779	RNA destabilization(GO:0050779)
6.5	85.0	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
6.5	19.6	GO:0046208	spermine catabolic process(GO:0046208)
6.5	13.1	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
6.5	39.1	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
6.5	6.5	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
6.5	13.0	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
6.5	52.0	GO:0035855	megakaryocyte development(GO:0035855)
6.5	32.5	GO:0016576	histone dephosphorylation(GO:0016576)
6.5	6.5	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
6.5	6.5	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
6.5	19.5	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
6.5	19.5	GO:0006393	termination of mitochondrial transcription(GO:0006393)
6.5	13.0	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
6.5	12.9	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
6.4	25.8	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
6.4	45.1	GO:0046040	IMP metabolic process(GO:0046040)
6.4	19.3	GO:0090085	regulation of protein deubiquitination(GO:0090085)
6.4	38.5	GO:0051639	actin filament network formation(GO:0051639)
6.4	12.8	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
6.4	19.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
6.4	6.4	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
6.4	127.5	GO:0006301	postreplication repair(GO:0006301)
6.4	19.1	GO:0042732	D-xylose metabolic process(GO:0042732)
6.4	6.4	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
6.4	44.6	GO:0030575	nuclear body organization(GO:0030575)
6.3	50.7	GO:0051014	actin filament severing(GO:0051014)
6.3	25.3	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
6.3	12.6	GO:0043627	response to estrogen(GO:0043627)
6.3	12.6	GO:0000255	allantoin metabolic process(GO:0000255)
6.3	18.9	GO:0033227	dsRNA transport(GO:0033227)
6.3	18.9	GO:1903715	regulation of aerobic respiration(GO:1903715)
6.3	31.5	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
6.3	25.1	GO:0042420	dopamine catabolic process(GO:0042420)
6.3	31.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
6.3	25.0	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
6.3	50.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
6.3	12.5	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
6.3	25.0	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
6.2	6.2	GO:0007127	meiosis I(GO:0007127)
6.2	24.9	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
6.2	6.2	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
6.2	31.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
6.2	6.2	GO:0018126	protein hydroxylation(GO:0018126)
6.2	12.4	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
6.2	31.0	GO:0097421	liver regeneration(GO:0097421)
6.2	37.2	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
6.2	18.6	GO:0006545	glycine biosynthetic process(GO:0006545)
6.2	18.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
6.1	6.1	GO:0006680	glucosylceramide catabolic process(GO:0006680)
6.1	18.4	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
6.1	43.0	GO:0035994	response to muscle stretch(GO:0035994)
6.1	6.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
6.1	30.7	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
6.1	61.3	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
6.1	12.3	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
6.1	18.4	GO:0000212	meiotic spindle organization(GO:0000212)
6.1	18.3	GO:0003096	renal sodium ion transport(GO:0003096)
6.1	24.5	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
6.1	6.1	GO:0048148	behavioral response to cocaine(GO:0048148)
6.1	24.4	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
6.1	6.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
6.1	24.3	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
6.0	18.1	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
6.0	12.0	GO:0010668	ectodermal cell differentiation(GO:0010668)
6.0	6.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
6.0	23.9	GO:0035405	histone-threonine phosphorylation(GO:0035405)
6.0	6.0	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
6.0	35.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
6.0	6.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
5.9	17.8	GO:0006499	N-terminal protein myristoylation(GO:0006499)
5.9	11.9	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
5.9	23.8	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
5.9	11.9	GO:0002679	respiratory burst involved in defense response(GO:0002679)
5.9	23.7	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
5.9	11.9	GO:0042304	regulation of fatty acid biosynthetic process(GO:0042304)
5.9	5.9	GO:0001922	B-1 B cell homeostasis(GO:0001922)
5.9	41.5	GO:0015838	amino-acid betaine transport(GO:0015838)
5.9	11.9	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
5.9	5.9	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
5.9	5.9	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
5.9	5.9	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
5.9	11.8	GO:0035928	rRNA import into mitochondrion(GO:0035928)
5.9	11.8	GO:0061073	ciliary body morphogenesis(GO:0061073)
5.9	17.7	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
5.8	93.5	GO:0050873	brown fat cell differentiation(GO:0050873)
5.8	46.8	GO:0006525	arginine metabolic process(GO:0006525)
5.8	17.5	GO:1904424	regulation of GTP binding(GO:1904424)
5.8	23.3	GO:0072553	terminal button organization(GO:0072553)
5.8	17.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
5.8	17.4	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
5.8	23.2	GO:0042448	progesterone metabolic process(GO:0042448)
5.8	52.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
5.8	34.6	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
5.8	11.5	GO:0051451	myoblast migration(GO:0051451)
5.8	23.1	GO:0032482	Rab protein signal transduction(GO:0032482)
5.8	5.8	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
5.8	57.6	GO:0001731	formation of translation preinitiation complex(GO:0001731)
5.7	5.7	GO:0034204	lipid translocation(GO:0034204)
5.7	79.7	GO:0035909	aorta morphogenesis(GO:0035909)
5.7	22.8	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
5.7	17.1	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
5.7	5.7	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
5.7	11.3	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
5.7	5.7	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
5.6	16.9	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
5.6	11.2	GO:0035988	chondrocyte proliferation(GO:0035988)
5.6	16.7	GO:0090435	protein localization to nuclear envelope(GO:0090435)
5.6	5.6	GO:0045918	negative regulation of cytolysis(GO:0045918)
5.6	22.3	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
5.6	11.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
5.6	16.7	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
5.6	11.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
5.6	16.7	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
5.6	11.1	GO:0006543	glutamine catabolic process(GO:0006543)
5.5	11.1	GO:0042119	neutrophil activation(GO:0042119)
5.5	38.7	GO:0032486	Rap protein signal transduction(GO:0032486)
5.5	11.1	GO:0030223	neutrophil differentiation(GO:0030223)
5.5	5.5	GO:0060235	lens induction in camera-type eye(GO:0060235)
5.5	11.0	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
5.5	16.5	GO:0035404	histone-serine phosphorylation(GO:0035404)
5.5	27.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
5.5	38.4	GO:0071318	cellular response to ATP(GO:0071318)
5.5	126.0	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
5.5	10.9	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
5.5	5.5	GO:0010869	regulation of receptor biosynthetic process(GO:0010869)
5.4	21.8	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
5.4	10.9	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
5.4	59.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
5.4	21.7	GO:0060352	cell adhesion molecule production(GO:0060352)
5.4	5.4	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
5.4	5.4	GO:0070254	mucus secretion(GO:0070254)
5.4	16.3	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
5.4	10.8	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
5.4	21.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
5.4	37.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
5.4	32.4	GO:0071398	cellular response to fatty acid(GO:0071398)
5.4	32.4	GO:0050917	sensory perception of umami taste(GO:0050917)
5.4	10.8	GO:0050955	thermoception(GO:0050955)
5.4	21.6	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
5.4	64.6	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
5.4	16.1	GO:1903334	positive regulation of protein folding(GO:1903334)
5.4	16.1	GO:0015744	succinate transport(GO:0015744)
5.4	5.4	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
5.4	32.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
5.4	26.8	GO:0033623	regulation of integrin activation(GO:0033623)
5.4	5.4	GO:0034239	regulation of macrophage fusion(GO:0034239)
5.4	10.7	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
5.3	5.3	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
5.3	5.3	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
5.3	10.7	GO:1901856	negative regulation of cellular respiration(GO:1901856)
5.3	42.7	GO:0043248	proteasome assembly(GO:0043248)
5.3	16.0	GO:0009838	abscission(GO:0009838)
5.3	21.3	GO:0051031	tRNA transport(GO:0051031)
5.3	16.0	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
5.3	10.6	GO:0007290	spermatid nucleus elongation(GO:0007290)
5.3	5.3	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
5.3	37.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
5.3	15.9	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
5.3	21.1	GO:0006057	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
5.3	26.4	GO:0001842	neural fold formation(GO:0001842)
5.3	63.3	GO:0006144	purine nucleobase metabolic process(GO:0006144)
5.3	5.3	GO:0010159	specification of organ position(GO:0010159)
5.3	21.1	GO:0034695	response to prostaglandin E(GO:0034695)
5.3	5.3	GO:0043983	histone H4-K12 acetylation(GO:0043983)
5.3	26.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
5.3	10.5	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
5.2	15.7	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
5.2	15.7	GO:0046112	nucleobase biosynthetic process(GO:0046112)
5.2	5.2	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
5.2	5.2	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
5.2	20.9	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
5.2	15.6	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
5.2	5.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
5.2	15.6	GO:1901679	nucleotide transmembrane transport(GO:1901679)
5.2	10.4	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
5.2	15.6	GO:0018879	biphenyl metabolic process(GO:0018879)
5.2	25.9	GO:0060903	positive regulation of meiosis I(GO:0060903)
5.2	139.7	GO:0043297	apical junction assembly(GO:0043297)
5.2	51.7	GO:0035767	endothelial cell chemotaxis(GO:0035767)
5.2	36.2	GO:0002183	cytoplasmic translational initiation(GO:0002183)
5.2	20.7	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
5.2	51.6	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
5.2	20.6	GO:0032790	ribosome disassembly(GO:0032790)
5.2	5.2	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
5.1	30.9	GO:0016266	O-glycan processing(GO:0016266)
5.1	15.4	GO:0021699	cerebellar cortex maturation(GO:0021699)
5.1	25.7	GO:0032020	ISG15-protein conjugation(GO:0032020)
5.1	25.7	GO:0000237	leptotene(GO:0000237)
5.1	20.5	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
5.1	15.4	GO:0007525	somatic muscle development(GO:0007525)
5.1	30.7	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
5.1	10.2	GO:1901800	positive regulation of proteasomal protein catabolic process(GO:1901800)
5.1	76.6	GO:0030865	cortical cytoskeleton organization(GO:0030865)
5.1	5.1	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
5.1	15.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
5.1	35.6	GO:0035372	protein localization to microtubule(GO:0035372)
5.1	45.8	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
5.1	20.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
5.1	15.2	GO:0019482	beta-alanine metabolic process(GO:0019482)
5.1	25.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
5.1	15.2	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
5.1	5.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
5.1	5.1	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
5.1	5.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715)
5.0	5.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
5.0	60.5	GO:0051601	exocyst localization(GO:0051601)
5.0	45.4	GO:0006750	glutathione biosynthetic process(GO:0006750)
5.0	10.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
5.0	50.3	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
5.0	10.0	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
5.0	5.0	GO:0010165	response to X-ray(GO:0010165)
5.0	35.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
5.0	30.1	GO:0002467	germinal center formation(GO:0002467)
5.0	20.1	GO:0070162	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
5.0	25.0	GO:0002553	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
5.0	5.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
5.0	29.9	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
5.0	5.0	GO:2000272	negative regulation of receptor activity(GO:2000272)
5.0	9.9	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
5.0	5.0	GO:0046174	polyol catabolic process(GO:0046174)
5.0	29.8	GO:0040016	embryonic cleavage(GO:0040016)
4.9	14.8	GO:0006670	sphingosine metabolic process(GO:0006670)
4.9	4.9	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
4.9	39.6	GO:0046697	decidualization(GO:0046697)
4.9	29.7	GO:0032594	protein transport within lipid bilayer(GO:0032594)
4.9	14.8	GO:0031100	organ regeneration(GO:0031100)
4.9	24.6	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
4.9	4.9	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
4.9	24.6	GO:0045017	glycerolipid biosynthetic process(GO:0045017)
4.9	14.7	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
4.9	9.8	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
4.9	14.7	GO:0090148	membrane fission(GO:0090148)
4.9	4.9	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
4.9	39.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
4.9	14.7	GO:0060613	fat pad development(GO:0060613)
4.9	29.3	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
4.9	4.9	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
4.9	43.8	GO:0032801	receptor catabolic process(GO:0032801)
4.9	9.7	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
4.9	14.6	GO:0070257	positive regulation of mucus secretion(GO:0070257)
4.8	19.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
4.8	24.1	GO:0070475	rRNA base methylation(GO:0070475)
4.8	38.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
4.8	9.6	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
4.8	19.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
4.8	14.3	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
4.8	4.8	GO:0080009	mRNA methylation(GO:0080009)
4.8	4.8	GO:1990928	response to amino acid starvation(GO:1990928)
4.8	14.3	GO:0097066	response to thyroid hormone(GO:0097066)
4.8	19.0	GO:0007144	female meiosis I(GO:0007144)
4.7	4.7	GO:0015889	cobalamin transport(GO:0015889)
4.7	38.0	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
4.7	14.2	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
4.7	23.7	GO:0048227	plasma membrane to endosome transport(GO:0048227)
4.7	14.2	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
4.7	4.7	GO:1903393	positive regulation of adherens junction organization(GO:1903393)
4.7	9.4	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628)
4.7	4.7	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
4.7	9.4	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
4.7	56.4	GO:0045116	protein neddylation(GO:0045116)
4.7	14.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
4.7	4.7	GO:0033327	Leydig cell differentiation(GO:0033327)
4.7	32.8	GO:0002115	store-operated calcium entry(GO:0002115)
4.7	9.3	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
4.7	9.3	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
4.7	9.3	GO:0006868	glutamine transport(GO:0006868)
4.7	18.6	GO:0044539	long-chain fatty acid import(GO:0044539)
4.7	14.0	GO:0061635	regulation of protein complex stability(GO:0061635)
4.6	18.5	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
4.6	32.4	GO:0051354	negative regulation of oxidoreductase activity(GO:0051354)
4.6	18.5	GO:0061042	vascular wound healing(GO:0061042)
4.6	13.9	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
4.6	4.6	GO:0001951	intestinal D-glucose absorption(GO:0001951)
4.6	4.6	GO:1901420	negative regulation of response to alcohol(GO:1901420)
4.6	4.6	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
4.6	23.0	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
4.6	18.3	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
4.6	32.1	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
4.6	4.6	GO:2000191	regulation of fatty acid transport(GO:2000191)
4.6	22.8	GO:0006702	androgen biosynthetic process(GO:0006702)
4.6	13.7	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
4.6	4.6	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
4.5	40.9	GO:0060009	Sertoli cell development(GO:0060009)
4.5	31.8	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
4.5	22.7	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
4.5	18.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
4.5	13.6	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
4.5	22.6	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
4.5	18.1	GO:0006083	acetate metabolic process(GO:0006083)
4.5	4.5	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
4.5	4.5	GO:0046782	regulation of viral transcription(GO:0046782)
4.5	36.1	GO:0044146	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
4.5	9.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
4.5	4.5	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
4.5	27.0	GO:0006561	proline biosynthetic process(GO:0006561)
4.5	27.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
4.5	22.4	GO:0046085	adenosine metabolic process(GO:0046085)
4.5	9.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
4.5	4.5	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
4.5	8.9	GO:0045792	negative regulation of cell size(GO:0045792)
4.5	22.3	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
4.4	22.2	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
4.4	4.4	GO:0002863	positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
4.4	8.9	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
4.4	8.9	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
4.4	39.8	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
4.4	4.4	GO:0019676	ammonia assimilation cycle(GO:0019676)
4.4	8.8	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
4.4	13.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
4.4	4.4	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
4.4	26.5	GO:0008063	Toll signaling pathway(GO:0008063)
4.4	8.8	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
4.4	4.4	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
4.4	4.4	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.4	4.4	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
4.4	61.3	GO:0000272	polysaccharide catabolic process(GO:0000272)
4.4	4.4	GO:0008090	retrograde axonal transport(GO:0008090)
4.4	17.5	GO:0080154	regulation of fertilization(GO:0080154)
4.4	61.1	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
4.3	39.1	GO:0002026	regulation of the force of heart contraction(GO:0002026)
4.3	47.8	GO:0045351	type I interferon biosynthetic process(GO:0045351)
4.3	56.4	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
4.3	26.0	GO:0033194	response to hydroperoxide(GO:0033194)
4.3	8.6	GO:0009826	unidimensional cell growth(GO:0009826)
4.3	25.9	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
4.3	8.6	GO:0060046	regulation of acrosome reaction(GO:0060046)
4.3	13.0	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
4.3	12.9	GO:0043504	mitochondrial DNA repair(GO:0043504)
4.3	4.3	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
4.3	4.3	GO:0046349	amino sugar biosynthetic process(GO:0046349)
4.3	4.3	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
4.3	4.3	GO:0035622	intrahepatic bile duct development(GO:0035622)
4.3	4.3	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
4.3	4.3	GO:0006551	leucine metabolic process(GO:0006551)
4.3	17.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
4.3	64.4	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
4.3	12.9	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
4.3	46.9	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
4.3	12.8	GO:0007021	tubulin complex assembly(GO:0007021)
4.3	8.5	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
4.3	8.5	GO:0042148	strand invasion(GO:0042148)
4.3	8.5	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
4.3	12.8	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
4.2	29.7	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
4.2	21.2	GO:0000103	sulfate assimilation(GO:0000103)
4.2	25.4	GO:0046889	positive regulation of lipid biosynthetic process(GO:0046889)
4.2	76.2	GO:0010761	fibroblast migration(GO:0010761)
4.2	4.2	GO:0007000	nucleolus organization(GO:0007000)
4.2	46.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
4.2	12.7	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
4.2	12.6	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
4.2	4.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
4.2	42.1	GO:0000305	response to oxygen radical(GO:0000305)
4.2	8.4	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
4.2	8.4	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
4.2	8.4	GO:0090009	primitive streak formation(GO:0090009)
4.2	8.4	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
4.2	4.2	GO:0032286	central nervous system myelin maintenance(GO:0032286)
4.2	8.3	GO:0018206	peptidyl-methionine modification(GO:0018206)
4.2	62.5	GO:0000060	protein import into nucleus, translocation(GO:0000060)
4.2	74.8	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
4.2	54.0	GO:0006730	one-carbon metabolic process(GO:0006730)
4.1	16.6	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
4.1	8.3	GO:0009404	toxin metabolic process(GO:0009404)
4.1	61.9	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
4.1	20.6	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
4.1	4.1	GO:0060914	heart formation(GO:0060914)
4.1	4.1	GO:0021571	rhombomere 5 development(GO:0021571)
4.1	8.2	GO:0071356	cellular response to tumor necrosis factor(GO:0071356)
4.1	20.5	GO:0034227	tRNA thio-modification(GO:0034227)
4.1	4.1	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
4.1	24.6	GO:0007097	nuclear migration(GO:0007097)
4.1	4.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
4.1	16.4	GO:0000012	single strand break repair(GO:0000012)
4.1	4.1	GO:0007398	ectoderm development(GO:0007398)
4.1	8.2	GO:0031034	myosin filament assembly(GO:0031034)
4.1	8.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
4.1	28.5	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
4.1	12.2	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
4.1	12.2	GO:0009142	nucleoside triphosphate biosynthetic process(GO:0009142)
4.1	12.2	GO:0001921	positive regulation of receptor recycling(GO:0001921)
4.1	12.2	GO:0051775	response to redox state(GO:0051775)
4.1	4.1	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
4.1	36.5	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
4.1	4.1	GO:0010884	positive regulation of lipid storage(GO:0010884)
4.1	8.1	GO:0030888	regulation of B cell proliferation(GO:0030888)
4.0	12.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
4.0	36.4	GO:0036159	inner dynein arm assembly(GO:0036159)
4.0	16.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
4.0	4.0	GO:0032148	activation of protein kinase B activity(GO:0032148)
4.0	4.0	GO:0031033	myosin filament organization(GO:0031033)
4.0	8.1	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
4.0	4.0	GO:0007100	mitotic centrosome separation(GO:0007100)
4.0	24.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
4.0	24.1	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
4.0	12.0	GO:0006449	regulation of translational termination(GO:0006449)
4.0	16.1	GO:0009446	putrescine biosynthetic process(GO:0009446)
4.0	4.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
4.0	12.0	GO:0046329	negative regulation of JNK cascade(GO:0046329)
4.0	8.0	GO:0099558	maintenance of synapse structure(GO:0099558)
4.0	51.9	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
4.0	8.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
4.0	19.9	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
4.0	4.0	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
4.0	15.9	GO:1903332	regulation of protein folding(GO:1903332)
4.0	4.0	GO:0003415	chondrocyte hypertrophy(GO:0003415)
4.0	15.9	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
4.0	11.9	GO:0015697	quaternary ammonium group transport(GO:0015697)
4.0	4.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
4.0	7.9	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
4.0	15.8	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
4.0	19.8	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.9	11.8	GO:0014043	negative regulation of neuron maturation(GO:0014043)
3.9	7.9	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
3.9	43.2	GO:0001945	lymph vessel development(GO:0001945)
3.9	11.8	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
3.9	43.2	GO:0035904	aorta development(GO:0035904)
3.9	11.8	GO:0033131	regulation of glucokinase activity(GO:0033131)
3.9	47.1	GO:0060674	placenta blood vessel development(GO:0060674)
3.9	15.7	GO:0090527	actin filament reorganization(GO:0090527)
3.9	117.5	GO:0010508	positive regulation of autophagy(GO:0010508)
3.9	3.9	GO:0031860	telomeric 3' overhang formation(GO:0031860)
3.9	3.9	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
3.9	3.9	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
3.9	3.9	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
3.9	15.6	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
3.9	7.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
3.9	7.8	GO:0003383	apical constriction(GO:0003383)
3.9	15.5	GO:0001893	maternal placenta development(GO:0001893)
3.9	7.8	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
3.9	38.8	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
3.9	23.2	GO:0008298	intracellular mRNA localization(GO:0008298)
3.9	7.7	GO:0070932	histone H3 deacetylation(GO:0070932)
3.9	65.7	GO:0006308	DNA catabolic process(GO:0006308)
3.9	61.8	GO:0010390	histone monoubiquitination(GO:0010390)
3.9	11.6	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
3.8	26.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
3.8	3.8	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
3.8	11.5	GO:0042737	drug catabolic process(GO:0042737)
3.8	3.8	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
3.8	23.0	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
3.8	11.5	GO:0006285	base-excision repair, AP site formation(GO:0006285)
3.8	3.8	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
3.8	65.0	GO:0006695	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
3.8	3.8	GO:0060481	lobar bronchus epithelium development(GO:0060481)
3.8	61.0	GO:0044380	protein localization to cytoskeleton(GO:0044380)
3.8	15.2	GO:0019695	choline metabolic process(GO:0019695)
3.8	19.0	GO:0032534	regulation of microvillus assembly(GO:0032534)
3.8	3.8	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
3.8	15.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
3.8	11.4	GO:2000303	regulation of ceramide biosynthetic process(GO:2000303)
3.8	11.4	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
3.8	15.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
3.8	34.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
3.8	3.8	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
3.8	18.9	GO:0015931	nucleobase-containing compound transport(GO:0015931)
3.8	3.8	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
3.8	37.6	GO:0007076	mitotic chromosome condensation(GO:0007076)
3.8	26.3	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
3.7	22.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
3.7	26.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
3.7	11.2	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
3.7	3.7	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
3.7	11.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
3.7	7.4	GO:0034720	histone H3-K4 demethylation(GO:0034720)
3.7	3.7	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
3.7	26.0	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
3.7	7.4	GO:0070268	cornification(GO:0070268)
3.7	11.1	GO:0060155	platelet dense granule organization(GO:0060155)
3.7	7.4	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
3.7	44.5	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
3.7	7.4	GO:0009189	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
3.7	7.4	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
3.7	11.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
3.7	51.8	GO:0017144	drug metabolic process(GO:0017144)
3.7	25.9	GO:0042574	retinal metabolic process(GO:0042574)
3.7	3.7	GO:0010893	positive regulation of steroid biosynthetic process(GO:0010893)
3.7	55.3	GO:0031648	protein destabilization(GO:0031648)
3.7	18.4	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
3.7	3.7	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
3.7	14.7	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
3.7	25.7	GO:0070189	kynurenine metabolic process(GO:0070189)
3.7	11.0	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
3.7	22.0	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
3.7	11.0	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.7	7.3	GO:0090400	stress-induced premature senescence(GO:0090400)
3.7	62.3	GO:0042832	defense response to protozoan(GO:0042832)
3.6	14.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
3.6	69.2	GO:0007520	myoblast fusion(GO:0007520)
3.6	7.3	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
3.6	7.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
3.6	25.5	GO:1901984	negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
3.6	3.6	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
3.6	25.3	GO:0051383	kinetochore organization(GO:0051383)
3.6	10.8	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
3.6	3.6	GO:0002071	glandular epithelial cell maturation(GO:0002071)
3.6	18.0	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
3.6	7.2	GO:0030049	muscle filament sliding(GO:0030049)
3.6	36.0	GO:0070166	enamel mineralization(GO:0070166)
3.6	14.4	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
3.6	3.6	GO:0008105	asymmetric protein localization(GO:0008105)
3.6	3.6	GO:0031061	negative regulation of histone methylation(GO:0031061)
3.6	35.9	GO:0002251	organ or tissue specific immune response(GO:0002251)
3.6	17.9	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
3.6	3.6	GO:0060700	regulation of ribonuclease activity(GO:0060700)
3.6	57.3	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
3.6	21.5	GO:0043117	positive regulation of vascular permeability(GO:0043117)
3.6	3.6	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
3.6	28.5	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
3.5	14.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
3.5	17.7	GO:0033344	cholesterol efflux(GO:0033344)
3.5	10.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
3.5	10.6	GO:1903727	positive regulation of phospholipid metabolic process(GO:1903727)
3.5	17.6	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
3.5	17.6	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
3.5	73.9	GO:0008286	insulin receptor signaling pathway(GO:0008286)
3.5	49.2	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
3.5	3.5	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
3.5	7.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.5	7.0	GO:0015819	lysine transport(GO:0015819)
3.5	20.9	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
3.5	10.5	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
3.5	3.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
3.5	10.4	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
3.5	6.9	GO:0016114	terpenoid biosynthetic process(GO:0016114)
3.5	6.9	GO:0033622	integrin activation(GO:0033622)
3.5	6.9	GO:0046487	glyoxylate metabolic process(GO:0046487)
3.5	17.3	GO:0032965	regulation of collagen biosynthetic process(GO:0032965)
3.5	20.7	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
3.4	10.3	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033)
3.4	13.8	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
3.4	10.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
3.4	3.4	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
3.4	6.9	GO:0051310	metaphase plate congression(GO:0051310)
3.4	10.3	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
3.4	6.9	GO:0030242	pexophagy(GO:0030242)
3.4	3.4	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
3.4	3.4	GO:0021570	rhombomere 4 development(GO:0021570)
3.4	3.4	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
3.4	6.8	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
3.4	3.4	GO:0071218	cellular response to misfolded protein(GO:0071218)
3.4	10.2	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
3.4	3.4	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
3.4	40.8	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
3.4	3.4	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
3.4	10.2	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
3.4	27.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
3.4	16.9	GO:0009650	UV protection(GO:0009650)
3.4	23.6	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
3.4	30.4	GO:0061436	establishment of skin barrier(GO:0061436)
3.4	13.5	GO:0060296	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
3.4	10.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
3.4	3.4	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
3.4	40.3	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
3.3	13.4	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
3.3	10.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
3.3	13.3	GO:0006857	oligopeptide transport(GO:0006857)
3.3	10.0	GO:0016264	gap junction assembly(GO:0016264)
3.3	3.3	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
3.3	26.6	GO:0060669	embryonic placenta morphogenesis(GO:0060669)
3.3	19.9	GO:0046686	response to cadmium ion(GO:0046686)
3.3	6.6	GO:0007379	segment specification(GO:0007379)
3.3	26.5	GO:0006013	mannose metabolic process(GO:0006013)
3.3	26.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
3.3	19.9	GO:0016556	mRNA modification(GO:0016556)
3.3	19.9	GO:0032096	negative regulation of response to food(GO:0032096)
3.3	9.9	GO:0071236	cellular response to antibiotic(GO:0071236)
3.3	6.6	GO:0006833	water transport(GO:0006833)
3.3	33.0	GO:0016578	histone deubiquitination(GO:0016578)
3.3	9.9	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
3.3	9.8	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.3	22.9	GO:0051292	nuclear pore complex assembly(GO:0051292)
3.3	9.8	GO:0009992	cellular water homeostasis(GO:0009992)
3.3	42.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
3.3	6.5	GO:0052472	modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
3.2	3.2	GO:0006949	syncytium formation(GO:0006949)
3.2	6.5	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
3.2	9.7	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
3.2	9.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
3.2	3.2	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
3.2	3.2	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
3.2	9.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
3.2	6.4	GO:0035511	oxidative DNA demethylation(GO:0035511)
3.2	6.4	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
3.2	57.5	GO:0030168	platelet activation(GO:0030168)
3.2	9.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
3.2	38.3	GO:0045214	sarcomere organization(GO:0045214)
3.2	38.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
3.2	3.2	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
3.2	25.4	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
3.2	6.3	GO:0010387	COP9 signalosome assembly(GO:0010387)
3.2	15.9	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
3.2	3.2	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
3.2	3.2	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
3.2	9.5	GO:0009299	mRNA transcription(GO:0009299)
3.2	28.5	GO:0040033	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
3.2	6.3	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
3.2	9.5	GO:0051231	spindle elongation(GO:0051231)
3.2	6.3	GO:0001555	oocyte growth(GO:0001555)
3.2	3.2	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
3.1	3.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
3.1	3.1	GO:0003162	atrioventricular node development(GO:0003162)
3.1	15.7	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
3.1	6.3	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
3.1	9.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
3.1	18.8	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
3.1	3.1	GO:0009445	putrescine metabolic process(GO:0009445)
3.1	12.5	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
3.1	9.4	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.1	28.1	GO:0035455	response to interferon-alpha(GO:0035455)
3.1	6.2	GO:0043084	penile erection(GO:0043084)
3.1	3.1	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
3.1	90.5	GO:0043966	histone H3 acetylation(GO:0043966)
3.1	6.2	GO:1903232	melanosome assembly(GO:1903232)
3.1	6.2	GO:0042398	cellular modified amino acid biosynthetic process(GO:0042398)
3.1	3.1	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
3.1	6.2	GO:0044375	regulation of peroxisome size(GO:0044375)
3.1	12.4	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
3.1	3.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
3.1	37.0	GO:0006471	protein ADP-ribosylation(GO:0006471)
3.1	9.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
3.1	3.1	GO:0098869	cellular oxidant detoxification(GO:0098869)
3.1	9.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
3.1	15.4	GO:0060539	diaphragm development(GO:0060539)
3.1	27.7	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
3.1	12.3	GO:0048739	cardiac muscle fiber development(GO:0048739)
3.1	52.0	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
3.1	12.2	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
3.1	12.2	GO:0042168	heme metabolic process(GO:0042168)
3.1	3.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
3.0	15.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
3.0	15.2	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
3.0	18.2	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
3.0	24.3	GO:0032438	melanosome organization(GO:0032438)
3.0	9.1	GO:0034421	post-translational protein acetylation(GO:0034421)
3.0	9.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
3.0	3.0	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
3.0	6.1	GO:0032570	response to progesterone(GO:0032570)
3.0	6.1	GO:2000354	regulation of ovarian follicle development(GO:2000354)
3.0	3.0	GO:0032823	regulation of natural killer cell differentiation(GO:0032823)
3.0	15.1	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
3.0	12.1	GO:0034969	histone arginine methylation(GO:0034969)
3.0	6.0	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
3.0	3.0	GO:1904528	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
3.0	9.0	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
3.0	15.0	GO:0009249	protein lipoylation(GO:0009249)
3.0	15.0	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
3.0	6.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
3.0	29.8	GO:0045047	protein targeting to ER(GO:0045047)
3.0	3.0	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
3.0	3.0	GO:0060591	chondroblast differentiation(GO:0060591)
3.0	3.0	GO:0032642	regulation of chemokine production(GO:0032642)
3.0	8.9	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
3.0	6.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
3.0	3.0	GO:0040009	regulation of growth rate(GO:0040009)
3.0	5.9	GO:0046877	regulation of saliva secretion(GO:0046877)
3.0	109.9	GO:0016125	sterol metabolic process(GO:0016125)
3.0	23.8	GO:0034030	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
3.0	5.9	GO:0002315	marginal zone B cell differentiation(GO:0002315)
3.0	20.8	GO:0015732	prostaglandin transport(GO:0015732)
3.0	8.9	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
3.0	5.9	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
2.9	11.8	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
2.9	87.9	GO:0055088	lipid homeostasis(GO:0055088)
2.9	2.9	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
2.9	8.8	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267)
2.9	5.8	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
2.9	20.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
2.9	26.2	GO:0070208	protein heterotrimerization(GO:0070208)
2.9	2.9	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
2.9	5.8	GO:0070544	histone H3-K36 demethylation(GO:0070544)
2.9	8.7	GO:0048539	bone marrow development(GO:0048539)
2.9	2.9	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
2.9	2.9	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
2.9	2.9	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
2.9	5.8	GO:0045922	negative regulation of fatty acid metabolic process(GO:0045922)
2.9	17.3	GO:0006353	DNA-templated transcription, termination(GO:0006353)
2.9	28.8	GO:0042407	cristae formation(GO:0042407)
2.9	37.4	GO:0003351	epithelial cilium movement(GO:0003351)
2.9	20.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
2.9	2.9	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
2.9	8.6	GO:0019348	dolichol metabolic process(GO:0019348)
2.9	5.7	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
2.9	5.7	GO:0015669	gas transport(GO:0015669)
2.9	14.3	GO:0031053	primary miRNA processing(GO:0031053)
2.9	17.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
2.8	11.4	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
2.8	8.5	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.8	5.7	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
2.8	5.7	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
2.8	19.8	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
2.8	45.2	GO:0006953	acute-phase response(GO:0006953)
2.8	5.6	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
2.8	19.7	GO:0031167	rRNA methylation(GO:0031167)
2.8	5.6	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.8	5.6	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
2.8	2.8	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
2.8	11.2	GO:0045060	negative thymic T cell selection(GO:0045060)
2.8	5.6	GO:0000729	DNA double-strand break processing(GO:0000729)
2.8	5.6	GO:0006801	superoxide metabolic process(GO:0006801)
2.8	2.8	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
2.8	2.8	GO:0007621	negative regulation of female receptivity(GO:0007621)
2.8	5.6	GO:0008209	androgen metabolic process(GO:0008209)
2.8	16.6	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.8	2.8	GO:0035813	renal sodium excretion(GO:0035812) regulation of renal sodium excretion(GO:0035813)
2.8	8.3	GO:0048819	regulation of hair follicle maturation(GO:0048819)
2.8	5.5	GO:0051661	maintenance of centrosome location(GO:0051661)
2.8	13.8	GO:0030449	regulation of complement activation(GO:0030449)
2.8	19.3	GO:0009648	photoperiodism(GO:0009648)
2.7	2.7	GO:0060300	regulation of cytokine activity(GO:0060300)
2.7	8.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
2.7	11.0	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
2.7	5.5	GO:0035461	vitamin transmembrane transport(GO:0035461)
2.7	5.5	GO:2000680	regulation of rubidium ion transport(GO:2000680) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
2.7	62.7	GO:0006289	nucleotide-excision repair(GO:0006289)
2.7	2.7	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
2.7	19.0	GO:0043471	regulation of carbohydrate catabolic process(GO:0043470) regulation of cellular carbohydrate catabolic process(GO:0043471)
2.7	13.6	GO:0060216	definitive hemopoiesis(GO:0060216)
2.7	2.7	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
2.7	16.3	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
2.7	27.2	GO:0061515	myeloid cell development(GO:0061515)
2.7	5.4	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
2.7	8.1	GO:0016574	histone ubiquitination(GO:0016574)
2.7	10.8	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
2.7	8.1	GO:0019079	viral genome replication(GO:0019079)
2.7	21.6	GO:0016601	Rac protein signal transduction(GO:0016601)
2.7	10.8	GO:0048680	positive regulation of axon regeneration(GO:0048680)
2.7	16.2	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
2.7	2.7	GO:0006999	nuclear pore organization(GO:0006999)
2.7	21.5	GO:0030261	chromosome condensation(GO:0030261)
2.7	24.2	GO:0048535	lymph node development(GO:0048535)
2.7	8.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
2.7	5.4	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
2.7	18.8	GO:0007569	cell aging(GO:0007569)
2.7	45.6	GO:0003009	skeletal muscle contraction(GO:0003009)
2.7	26.8	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
2.7	5.4	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
2.7	5.3	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
2.7	5.3	GO:0019042	viral latency(GO:0019042)
2.7	61.3	GO:0051782	negative regulation of cell division(GO:0051782)
2.7	8.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
2.7	61.1	GO:0006505	GPI anchor metabolic process(GO:0006505)
2.7	47.7	GO:0032008	positive regulation of TOR signaling(GO:0032008)
2.7	5.3	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
2.6	18.5	GO:0006896	Golgi to vacuole transport(GO:0006896)
2.6	7.9	GO:0016242	negative regulation of macroautophagy(GO:0016242)
2.6	2.6	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
2.6	18.5	GO:0052697	xenobiotic glucuronidation(GO:0052697)
2.6	13.2	GO:0000154	rRNA modification(GO:0000154)
2.6	5.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
2.6	2.6	GO:0051307	meiotic chromosome separation(GO:0051307)
2.6	20.9	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
2.6	10.5	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785)
2.6	7.8	GO:0001302	replicative cell aging(GO:0001302)
2.6	20.9	GO:0070306	lens fiber cell differentiation(GO:0070306)
2.6	15.6	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
2.6	5.2	GO:0051444	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
2.6	2.6	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
2.6	15.6	GO:0097286	iron ion import(GO:0097286)
2.6	5.2	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
2.6	13.0	GO:0035269	protein O-linked mannosylation(GO:0035269)
2.6	10.4	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
2.6	5.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
2.6	7.8	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
2.6	20.7	GO:0042992	negative regulation of transcription factor import into nucleus(GO:0042992)
2.6	12.9	GO:0051013	microtubule severing(GO:0051013)
2.6	43.8	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
2.6	5.2	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
2.6	18.0	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
2.6	2.6	GO:0014827	intestine smooth muscle contraction(GO:0014827)
2.6	2.6	GO:0006681	galactosylceramide metabolic process(GO:0006681)
2.6	2.6	GO:0016045	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
2.6	15.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
2.6	56.1	GO:0008654	phospholipid biosynthetic process(GO:0008654)
2.6	20.4	GO:0032007	negative regulation of TOR signaling(GO:0032007)
2.5	28.0	GO:0035456	response to interferon-beta(GO:0035456)
2.5	2.5	GO:0006007	glucose catabolic process(GO:0006007)
2.5	81.3	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
2.5	2.5	GO:0014866	skeletal myofibril assembly(GO:0014866)
2.5	96.5	GO:0043330	response to exogenous dsRNA(GO:0043330)
2.5	7.6	GO:2000210	positive regulation of anoikis(GO:2000210)
2.5	10.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
2.5	5.0	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
2.5	27.6	GO:2000785	regulation of autophagosome assembly(GO:2000785)
2.5	17.6	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
2.5	15.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
2.5	2.5	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
2.5	2.5	GO:0046599	regulation of centriole replication(GO:0046599)
2.5	2.5	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
2.5	2.5	GO:0071895	odontoblast differentiation(GO:0071895)
2.5	12.5	GO:1904970	brush border assembly(GO:1904970)
2.5	25.0	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
2.5	2.5	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)
2.5	131.9	GO:0051236	nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
2.5	5.0	GO:0032494	response to peptidoglycan(GO:0032494)
2.5	24.7	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
2.5	39.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
2.5	9.8	GO:0007141	male meiosis I(GO:0007141)
2.5	4.9	GO:0032873	negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
2.5	7.4	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
2.4	66.1	GO:0006611	protein export from nucleus(GO:0006611)
2.4	2.4	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
2.4	12.2	GO:0051026	chiasma assembly(GO:0051026)
2.4	19.5	GO:0008340	determination of adult lifespan(GO:0008340)
2.4	2.4	GO:0070989	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) oxidative demethylation(GO:0070989)
2.4	7.3	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
2.4	2.4	GO:0042348	regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
2.4	2.4	GO:0009112	nucleobase metabolic process(GO:0009112)
2.4	82.3	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
2.4	4.8	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
2.4	4.8	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
2.4	2.4	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
2.4	14.5	GO:0019370	leukotriene biosynthetic process(GO:0019370)
2.4	38.5	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
2.4	134.7	GO:0006650	glycerophospholipid metabolic process(GO:0006650)
2.4	31.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
2.4	9.6	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
2.4	33.5	GO:0016575	histone deacetylation(GO:0016575)
2.4	2.4	GO:0000966	RNA 5'-end processing(GO:0000966)
2.4	4.8	GO:0002215	defense response to nematode(GO:0002215)
2.4	9.5	GO:1901985	positive regulation of protein acetylation(GO:1901985)
2.4	4.7	GO:0040031	snRNA modification(GO:0040031)
2.4	11.8	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
2.4	2.4	GO:0001562	response to protozoan(GO:0001562)
2.4	16.5	GO:0042770	signal transduction in response to DNA damage(GO:0042770)
2.4	7.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
2.3	11.7	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
2.3	18.7	GO:0072678	T cell migration(GO:0072678)
2.3	7.0	GO:1903276	regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
2.3	46.6	GO:0002687	positive regulation of leukocyte migration(GO:0002687)
2.3	32.5	GO:0060325	face morphogenesis(GO:0060325)
2.3	16.2	GO:0031929	TOR signaling(GO:0031929)
2.3	9.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
2.3	6.9	GO:0044773	mitotic DNA damage checkpoint(GO:0044773)
2.3	32.3	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
2.3	60.0	GO:0006749	glutathione metabolic process(GO:0006749)
2.3	4.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
2.3	23.1	GO:0043489	RNA stabilization(GO:0043489)
2.3	9.2	GO:1903318	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
2.3	2.3	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
2.3	11.5	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
2.3	11.5	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
2.3	6.9	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
2.3	38.9	GO:0051865	protein autoubiquitination(GO:0051865)
2.3	2.3	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
2.3	6.8	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
2.3	4.6	GO:0086043	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
2.3	27.3	GO:0016073	snRNA metabolic process(GO:0016073)
2.3	6.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.3	20.3	GO:1903146	regulation of mitophagy(GO:1903146)
2.3	6.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
2.3	27.1	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
2.2	2.2	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
2.2	6.7	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
2.2	13.5	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
2.2	2.2	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
2.2	4.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
2.2	4.5	GO:1902415	regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
2.2	13.4	GO:0070269	pyroptosis(GO:0070269)
2.2	24.4	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
2.2	8.9	GO:0043206	extracellular fibril organization(GO:0043206)
2.2	2.2	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
2.2	8.8	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
2.2	15.3	GO:0051568	histone H3-K4 methylation(GO:0051568)
2.2	2.2	GO:0006533	aspartate catabolic process(GO:0006533)
2.2	2.2	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
2.2	17.4	GO:1901998	toxin transport(GO:1901998)
2.2	69.6	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
2.2	4.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
2.2	4.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
2.2	2.2	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
2.2	4.3	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.2	10.8	GO:0001771	immunological synapse formation(GO:0001771)
2.1	8.5	GO:0072501	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
2.1	2.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.1	2.1	GO:0033046	negative regulation of sister chromatid segregation(GO:0033046) negative regulation of chromosome segregation(GO:0051985)
2.1	19.1	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
2.1	2.1	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
2.1	8.5	GO:0006903	vesicle targeting(GO:0006903)
2.1	4.2	GO:0001777	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
2.1	6.4	GO:0032474	otolith morphogenesis(GO:0032474)
2.1	65.3	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
2.1	6.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
2.1	4.2	GO:0018022	peptidyl-lysine methylation(GO:0018022)
2.1	6.3	GO:0045059	positive thymic T cell selection(GO:0045059)
2.1	6.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
2.1	4.2	GO:0001757	somite specification(GO:0001757)
2.1	25.0	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
2.1	12.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
2.1	10.4	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
2.1	4.1	GO:0070266	necroptotic process(GO:0070266)
2.1	6.2	GO:0034508	centromere complex assembly(GO:0034508)
2.1	6.2	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
2.1	20.6	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
2.1	2.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
2.0	2.0	GO:0051900	regulation of mitochondrial depolarization(GO:0051900)
2.0	16.3	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
2.0	2.0	GO:2001212	regulation of vasculogenesis(GO:2001212)
2.0	85.3	GO:0016579	protein deubiquitination(GO:0016579)
2.0	4.1	GO:0033572	transferrin transport(GO:0033572)
2.0	14.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
2.0	2.0	GO:0090656	t-circle formation(GO:0090656)
2.0	6.0	GO:0015781	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
2.0	8.0	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.0	8.0	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
2.0	13.9	GO:0031468	nuclear envelope reassembly(GO:0031468)
2.0	17.9	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
2.0	4.0	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
2.0	4.0	GO:0048251	elastic fiber assembly(GO:0048251)
2.0	2.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
2.0	27.6	GO:0006829	zinc II ion transport(GO:0006829)
1.9	3.9	GO:0044838	cell quiescence(GO:0044838)
1.9	5.8	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.9	17.4	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
1.9	17.4	GO:0060487	lung epithelial cell differentiation(GO:0060487)
1.9	3.9	GO:0071353	cellular response to interleukin-4(GO:0071353)
1.9	9.6	GO:0009218	pyrimidine ribonucleotide metabolic process(GO:0009218) pyrimidine ribonucleotide biosynthetic process(GO:0009220) pyrimidine ribonucleoside biosynthetic process(GO:0046132)
1.9	5.8	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
1.9	1.9	GO:0015791	polyol transport(GO:0015791)
1.9	34.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
1.9	1.9	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
1.9	3.8	GO:0033275	actin-myosin filament sliding(GO:0033275)
1.9	7.6	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
1.9	9.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
1.9	11.4	GO:1900015	regulation of cytokine production involved in inflammatory response(GO:1900015)
1.9	39.9	GO:1905039	organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039)
1.9	34.2	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
1.9	3.8	GO:0036010	protein localization to endosome(GO:0036010)
1.9	22.7	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
1.9	1.9	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.9	5.6	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.9	3.7	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
1.9	1.9	GO:0048865	stem cell fate commitment(GO:0048865)
1.9	61.5	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
1.9	40.9	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
1.9	13.0	GO:0006182	cGMP biosynthetic process(GO:0006182)
1.8	12.9	GO:0019377	glycolipid catabolic process(GO:0019377)
1.8	5.5	GO:0042755	eating behavior(GO:0042755)
1.8	1.8	GO:2000316	regulation of T-helper 17 type immune response(GO:2000316)
1.8	16.5	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
1.8	1.8	GO:0050926	regulation of positive chemotaxis(GO:0050926)
1.8	1.8	GO:0034501	protein localization to kinetochore(GO:0034501)
1.8	12.8	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
1.8	9.1	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814)
1.8	43.7	GO:0000027	ribosomal large subunit assembly(GO:0000027)
1.8	5.4	GO:0072528	pyrimidine-containing compound biosynthetic process(GO:0072528)
1.8	3.6	GO:0009313	oligosaccharide catabolic process(GO:0009313)
1.8	7.2	GO:1901992	positive regulation of mitotic cell cycle phase transition(GO:1901992)
1.8	5.4	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
1.8	9.0	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
1.8	7.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
1.8	3.6	GO:0070542	response to fatty acid(GO:0070542)
1.8	5.3	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
1.8	5.3	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
1.8	5.3	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
1.8	7.0	GO:0060840	artery development(GO:0060840)
1.8	5.3	GO:0032869	cellular response to insulin stimulus(GO:0032869)
1.8	24.5	GO:0000266	mitochondrial fission(GO:0000266)
1.8	14.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
1.7	5.2	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
1.7	3.5	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.7	1.7	GO:0048247	lymphocyte chemotaxis(GO:0048247)
1.7	5.2	GO:2000505	regulation of energy homeostasis(GO:2000505)
1.7	1.7	GO:0051657	maintenance of organelle location(GO:0051657)
1.7	1.7	GO:0071280	cellular response to copper ion(GO:0071280)
1.7	5.2	GO:0014807	regulation of somitogenesis(GO:0014807)
1.7	13.8	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
1.7	3.4	GO:0007603	phototransduction, visible light(GO:0007603)
1.7	5.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
1.7	3.4	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
1.7	5.1	GO:0006768	biotin metabolic process(GO:0006768)
1.7	8.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
1.7	8.5	GO:0002176	male germ cell proliferation(GO:0002176)
1.7	8.4	GO:0046037	GMP metabolic process(GO:0046037)
1.7	10.1	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
1.7	3.4	GO:0002551	mast cell chemotaxis(GO:0002551)
1.7	33.5	GO:0045103	intermediate filament-based process(GO:0045103)
1.7	1.7	GO:0021943	formation of radial glial scaffolds(GO:0021943)
1.7	1.7	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
1.7	1.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
1.7	1.7	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
1.7	1.7	GO:0044110	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117)
1.7	3.3	GO:0060017	parathyroid gland development(GO:0060017)
1.7	11.6	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
1.6	6.6	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
1.6	14.8	GO:0051168	nuclear export(GO:0051168)
1.6	18.1	GO:0006879	cellular iron ion homeostasis(GO:0006879)
1.6	24.6	GO:0006446	regulation of translational initiation(GO:0006446)
1.6	3.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
1.6	6.5	GO:0050832	defense response to fungus(GO:0050832)
1.6	3.3	GO:1990266	neutrophil migration(GO:1990266)
1.6	1.6	GO:0015747	urate transport(GO:0015747)
1.6	52.0	GO:0007052	mitotic spindle organization(GO:0007052)
1.6	1.6	GO:0043400	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) positive regulation of glucocorticoid secretion(GO:2000851)
1.6	17.8	GO:0015693	magnesium ion transport(GO:0015693)
1.6	3.2	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
1.6	6.4	GO:0048733	sebaceous gland development(GO:0048733)
1.6	1.6	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
1.6	3.2	GO:0035112	genitalia morphogenesis(GO:0035112)
1.6	8.0	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.6	1.6	GO:0005984	disaccharide metabolic process(GO:0005984)
1.6	3.2	GO:0006532	aspartate biosynthetic process(GO:0006532)
1.6	3.2	GO:0070170	regulation of tooth mineralization(GO:0070170)
1.6	1.6	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
1.6	11.1	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.6	1.6	GO:1902969	mitotic DNA replication(GO:1902969)
1.6	34.6	GO:0010501	RNA secondary structure unwinding(GO:0010501)
1.6	1.6	GO:0072718	response to cisplatin(GO:0072718)
1.6	40.5	GO:0045454	cell redox homeostasis(GO:0045454)
1.6	9.3	GO:0034587	piRNA metabolic process(GO:0034587)
1.6	1.6	GO:0072053	renal inner medulla development(GO:0072053)
1.6	9.3	GO:0006284	base-excision repair(GO:0006284)
1.6	6.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
1.6	20.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
1.6	4.7	GO:0009988	cell-cell recognition(GO:0009988)
1.6	1.6	GO:0018065	protein-cofactor linkage(GO:0018065)
1.6	10.9	GO:0051205	protein insertion into membrane(GO:0051205)
1.5	21.7	GO:0042403	thyroid hormone metabolic process(GO:0042403)
1.5	3.1	GO:0061045	negative regulation of wound healing(GO:0061045)
1.5	7.7	GO:1902017	regulation of cilium assembly(GO:1902017)
1.5	34.0	GO:0002181	cytoplasmic translation(GO:0002181)
1.5	17.0	GO:0007588	excretion(GO:0007588)
1.5	3.1	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
1.5	30.8	GO:0018345	protein palmitoylation(GO:0018345)
1.5	1.5	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
1.5	3.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.5	1.5	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
1.5	16.8	GO:0000470	maturation of LSU-rRNA(GO:0000470)
1.5	3.1	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
1.5	1.5	GO:0009994	oocyte differentiation(GO:0009994)
1.5	1.5	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
1.5	1.5	GO:0042537	benzene-containing compound metabolic process(GO:0042537)
1.5	1.5	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
1.5	3.0	GO:1904683	regulation of metalloendopeptidase activity(GO:1904683)
1.5	1.5	GO:0048070	regulation of developmental pigmentation(GO:0048070)
1.5	16.7	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
1.5	7.6	GO:0008053	mitochondrial fusion(GO:0008053)
1.5	3.0	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239)
1.5	15.1	GO:0015909	long-chain fatty acid transport(GO:0015909)
1.5	3.0	GO:0042628	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
1.5	3.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
1.5	1.5	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
1.5	1.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
1.5	3.0	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
1.5	6.0	GO:0006968	cellular defense response(GO:0006968)
1.5	1.5	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
1.5	6.0	GO:0006528	asparagine metabolic process(GO:0006528)
1.5	3.0	GO:0034505	tooth mineralization(GO:0034505)
1.5	4.4	GO:2000253	positive regulation of feeding behavior(GO:2000253)
1.5	4.4	GO:0070197	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.5	2.9	GO:0010039	response to iron ion(GO:0010039)
1.5	7.3	GO:0030104	water homeostasis(GO:0030104)
1.5	22.0	GO:0006491	N-glycan processing(GO:0006491)
1.5	1.5	GO:0030382	sperm mitochondrion organization(GO:0030382)
1.5	2.9	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
1.5	13.1	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.5	29.1	GO:0031424	keratinization(GO:0031424)
1.5	4.4	GO:0042074	cell migration involved in gastrulation(GO:0042074)
1.4	67.8	GO:0032259	methylation(GO:0032259)
1.4	2.9	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
1.4	11.5	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
1.4	1.4	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.4	2.9	GO:0060453	regulation of gastric acid secretion(GO:0060453)
1.4	8.5	GO:0010507	negative regulation of autophagy(GO:0010507)
1.4	2.8	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.4	7.1	GO:0001706	endoderm formation(GO:0001706)
1.4	22.6	GO:0071346	cellular response to interferon-gamma(GO:0071346)
1.4	4.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.4	4.2	GO:0070126	mitochondrial translational termination(GO:0070126)
1.4	1.4	GO:0035162	embryonic hemopoiesis(GO:0035162)
1.4	15.4	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
1.4	1.4	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
1.4	1.4	GO:0000722	telomere maintenance via recombination(GO:0000722)
1.4	23.8	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
1.4	22.4	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
1.4	2.8	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434)
1.4	5.5	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
1.4	33.2	GO:0098840	protein transport along microtubule(GO:0098840)
1.4	17.8	GO:0034101	erythrocyte homeostasis(GO:0034101)
1.4	1.4	GO:0032673	regulation of interleukin-4 production(GO:0032673)
1.4	2.7	GO:0003352	regulation of cilium movement(GO:0003352)
1.4	4.1	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
1.4	20.4	GO:0015914	phospholipid transport(GO:0015914)
1.4	4.1	GO:0007126	meiotic nuclear division(GO:0007126)
1.4	15.0	GO:0019835	cytolysis(GO:0019835)
1.4	20.4	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
1.4	2.7	GO:0006348	chromatin silencing at telomere(GO:0006348)
1.4	1.4	GO:0060676	ureteric bud formation(GO:0060676)
1.4	9.5	GO:0045445	myoblast differentiation(GO:0045445)
1.3	1.3	GO:0010002	cardioblast differentiation(GO:0010002)
1.3	28.3	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
1.3	2.7	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
1.3	5.4	GO:0042255	ribosome assembly(GO:0042255)
1.3	48.1	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
1.3	8.0	GO:0032060	bleb assembly(GO:0032060)
1.3	10.7	GO:0044804	nucleophagy(GO:0044804)
1.3	25.3	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
1.3	120.8	GO:0010466	negative regulation of peptidase activity(GO:0010466)
1.3	4.0	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
1.3	2.7	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
1.3	4.0	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.3	5.3	GO:0098534	centriole assembly(GO:0098534)
1.3	2.6	GO:0006817	phosphate ion transport(GO:0006817)
1.3	2.6	GO:0071168	protein localization to chromatin(GO:0071168)
1.3	2.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.3	3.9	GO:0060717	chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
1.3	27.3	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
1.3	1.3	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
1.3	11.6	GO:0007585	respiratory gaseous exchange(GO:0007585)
1.3	15.5	GO:0016573	histone acetylation(GO:0016573)
1.3	3.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
1.3	6.4	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.3	25.5	GO:0030042	actin filament depolymerization(GO:0030042)
1.3	8.9	GO:0016926	protein desumoylation(GO:0016926)
1.3	38.2	GO:0032543	mitochondrial translation(GO:0032543)
1.3	2.5	GO:2000379	positive regulation of reactive oxygen species metabolic process(GO:2000379)
1.3	1.3	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
1.3	10.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
1.3	2.5	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
1.2	2.5	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
1.2	2.5	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
1.2	7.4	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
1.2	2.5	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
1.2	8.6	GO:0022617	extracellular matrix disassembly(GO:0022617)
1.2	2.5	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.2	3.7	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
1.2	199.9	GO:0008380	RNA splicing(GO:0008380)
1.2	2.4	GO:0043687	post-translational protein modification(GO:0043687)
1.2	2.4	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
1.2	6.0	GO:0042474	middle ear morphogenesis(GO:0042474)
1.2	1.2	GO:0002638	negative regulation of immunoglobulin production(GO:0002638)
1.2	6.0	GO:0032355	response to estradiol(GO:0032355)
1.2	4.8	GO:0036158	outer dynein arm assembly(GO:0036158)
1.2	2.4	GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
1.2	3.6	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
1.2	1.2	GO:0051132	NK T cell activation(GO:0051132)
1.2	1.2	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
1.2	7.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
1.2	30.5	GO:1903749	positive regulation of establishment of protein localization to mitochondrion(GO:1903749)
1.2	1.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
1.2	3.5	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
1.2	7.0	GO:0015893	drug transport(GO:0015893)
1.2	4.7	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
1.2	1.2	GO:0033684	regulation of luteinizing hormone secretion(GO:0033684)
1.2	5.8	GO:0071985	multivesicular body sorting pathway(GO:0071985)
1.2	9.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.2	6.9	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
1.1	1.1	GO:0015884	folic acid transport(GO:0015884)
1.1	1.1	GO:0045651	positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
1.1	4.6	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
1.1	4.5	GO:0007130	synaptonemal complex assembly(GO:0007130)
1.1	16.8	GO:0007051	spindle organization(GO:0007051)
1.1	3.3	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.1	2.2	GO:0006776	vitamin A metabolic process(GO:0006776)
1.1	5.5	GO:0030193	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
1.1	6.6	GO:0002327	immature B cell differentiation(GO:0002327)
1.1	4.4	GO:0018208	peptidyl-proline modification(GO:0018208)
1.1	7.7	GO:0046676	negative regulation of insulin secretion(GO:0046676)
1.1	1.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
1.1	6.6	GO:0051321	meiotic cell cycle(GO:0051321)
1.1	4.4	GO:0070286	axonemal dynein complex assembly(GO:0070286)
1.1	5.5	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
1.1	3.3	GO:0019321	pentose metabolic process(GO:0019321)
1.1	2.2	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
1.1	2.2	GO:0038092	nodal signaling pathway(GO:0038092)
1.1	3.2	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
1.1	2.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
1.1	2.1	GO:2000401	regulation of lymphocyte migration(GO:2000401)
1.1	19.1	GO:0009201	ribonucleoside triphosphate biosynthetic process(GO:0009201)
1.1	19.1	GO:0007596	blood coagulation(GO:0007596)
1.1	1.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.1	3.2	GO:0072189	ureter development(GO:0072189)
1.1	2.1	GO:0006458	'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
1.1	5.3	GO:0051450	myoblast proliferation(GO:0051450)
1.1	5.3	GO:0006997	nucleus organization(GO:0006997)
1.1	2.1	GO:0061085	regulation of histone H3-K27 methylation(GO:0061085)
1.0	3.1	GO:0044458	motile cilium assembly(GO:0044458)
1.0	3.1	GO:0006450	regulation of translational fidelity(GO:0006450)
1.0	1.0	GO:0019372	lipoxygenase pathway(GO:0019372)
1.0	7.3	GO:0001522	pseudouridine synthesis(GO:0001522)
1.0	1.0	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
1.0	2.1	GO:0033280	response to vitamin D(GO:0033280)
1.0	1.0	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
1.0	36.9	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
1.0	3.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.0	30.6	GO:0006633	fatty acid biosynthetic process(GO:0006633)
1.0	80.6	GO:0043547	positive regulation of GTPase activity(GO:0043547)
1.0	3.1	GO:0001759	organ induction(GO:0001759)
1.0	3.0	GO:0046415	urate metabolic process(GO:0046415)
1.0	6.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
1.0	43.4	GO:0035308	negative regulation of protein dephosphorylation(GO:0035308)
1.0	4.0	GO:0006012	galactose metabolic process(GO:0006012)
1.0	7.1	GO:0046364	monosaccharide biosynthetic process(GO:0046364)
1.0	2.0	GO:0006475	internal protein amino acid acetylation(GO:0006475)
1.0	24.0	GO:0006958	complement activation, classical pathway(GO:0006958)
1.0	2.0	GO:0051346	negative regulation of hydrolase activity(GO:0051346)
1.0	1.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
1.0	4.8	GO:0045824	negative regulation of innate immune response(GO:0045824)
1.0	1.0	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.0	2.9	GO:0060438	trachea development(GO:0060438)
1.0	7.7	GO:0090280	positive regulation of calcium ion import(GO:0090280)
1.0	7.7	GO:0048144	fibroblast proliferation(GO:0048144)
1.0	5.8	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
1.0	78.5	GO:0032496	response to lipopolysaccharide(GO:0032496)
1.0	2.9	GO:0046836	glycolipid transport(GO:0046836)
0.9	5.7	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.9	8.5	GO:0007492	endoderm development(GO:0007492)
0.9	0.9	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.9	0.9	GO:0010155	regulation of proton transport(GO:0010155)
0.9	5.6	GO:0035608	protein deglutamylation(GO:0035608)
0.9	0.9	GO:0048069	eye pigmentation(GO:0048069)
0.9	1.8	GO:0030321	transepithelial chloride transport(GO:0030321)
0.9	0.9	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.9	36.6	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.9	2.7	GO:2000641	regulation of early endosome to late endosome transport(GO:2000641)
0.9	9.0	GO:0030574	collagen catabolic process(GO:0030574)
0.9	0.9	GO:0006624	vacuolar protein processing(GO:0006624)
0.9	1.8	GO:1901317	regulation of sperm motility(GO:1901317) positive regulation of sperm motility(GO:1902093)
0.9	0.9	GO:0070459	prolactin secretion(GO:0070459)
0.9	20.6	GO:0006310	DNA recombination(GO:0006310)
0.9	1.8	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.9	150.6	GO:0006412	translation(GO:0006412)
0.9	1.8	GO:0032098	regulation of appetite(GO:0032098)
0.9	2.6	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.9	0.9	GO:0097186	amelogenesis(GO:0097186)
0.9	7.0	GO:0071467	cellular response to pH(GO:0071467)
0.9	2.6	GO:0060037	pharyngeal system development(GO:0060037)
0.9	6.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.8	0.8	GO:0038161	prolactin signaling pathway(GO:0038161)
0.8	1.7	GO:0006265	DNA topological change(GO:0006265)
0.8	10.7	GO:0048240	sperm capacitation(GO:0048240)
0.8	2.5	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.8	2.5	GO:0045123	cellular extravasation(GO:0045123)
0.8	3.2	GO:1902750	negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.8	17.0	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.8	2.4	GO:0001556	oocyte maturation(GO:0001556)
0.8	51.6	GO:0006954	inflammatory response(GO:0006954)
0.8	0.8	GO:0001880	Mullerian duct regression(GO:0001880)
0.8	3.9	GO:0040029	regulation of gene expression, epigenetic(GO:0040029)
0.8	4.7	GO:0097194	execution phase of apoptosis(GO:0097194)
0.8	1.5	GO:0006706	steroid catabolic process(GO:0006706)
0.8	21.5	GO:0007059	chromosome segregation(GO:0007059)
0.8	5.3	GO:0042246	tissue regeneration(GO:0042246)
0.8	6.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.8	5.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.7	4.5	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.7	3.7	GO:0070646	protein modification by small protein removal(GO:0070646)
0.7	2.2	GO:0001659	temperature homeostasis(GO:0001659)
0.7	0.7	GO:0006577	amino-acid betaine metabolic process(GO:0006577)
0.7	0.7	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.7	2.9	GO:0018095	protein polyglutamylation(GO:0018095)
0.7	0.7	GO:0045621	positive regulation of lymphocyte differentiation(GO:0045621)
0.7	23.0	GO:0006631	fatty acid metabolic process(GO:0006631)
0.7	0.7	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.7	0.7	GO:0001692	histamine metabolic process(GO:0001692)
0.7	1.4	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.7	4.1	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.7	0.7	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.7	0.7	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.7	1.3	GO:0051196	regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
0.6	1.9	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.6	2.6	GO:0006302	double-strand break repair(GO:0006302)
0.6	2.6	GO:0034982	mitochondrial protein processing(GO:0034982)
0.6	1.3	GO:0002585	positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
0.6	1.3	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.6	1.3	GO:0033273	response to vitamin(GO:0033273)
0.6	0.6	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.6	0.6	GO:0035973	aggrephagy(GO:0035973)
0.6	3.1	GO:0033013	tetrapyrrole metabolic process(GO:0033013)
0.6	1.9	GO:0001773	myeloid dendritic cell activation(GO:0001773)
0.6	4.3	GO:0009303	rRNA transcription(GO:0009303)
0.6	0.6	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.6	0.6	GO:0046631	alpha-beta T cell activation(GO:0046631)
0.6	1.2	GO:0071548	response to dexamethasone(GO:0071548)
0.6	0.6	GO:0097192	signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.6	1.8	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.6	3.6	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.6	27.8	GO:0016042	lipid catabolic process(GO:0016042)
0.6	0.6	GO:0009620	response to fungus(GO:0009620)
0.6	0.6	GO:0021670	lateral ventricle development(GO:0021670)
0.6	0.6	GO:0015874	norepinephrine transport(GO:0015874)
0.6	2.3	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.6	0.6	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.6	1.7	GO:0050810	regulation of lipid biosynthetic process(GO:0046890) regulation of steroid biosynthetic process(GO:0050810)
0.6	0.6	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.6	0.6	GO:0009624	response to nematode(GO:0009624)
0.6	21.6	GO:0006457	protein folding(GO:0006457)
0.5	16.5	GO:0022613	ribonucleoprotein complex biogenesis(GO:0022613)
0.5	94.5	GO:0007283	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.5	12.0	GO:0006974	cellular response to DNA damage stimulus(GO:0006974)
0.5	1.6	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5	0.5	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.5	3.7	GO:0032204	regulation of telomere maintenance(GO:0032204)
0.5	0.5	GO:0060618	nipple development(GO:0060618)
0.5	0.5	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.5	0.5	GO:0031570	DNA integrity checkpoint(GO:0031570)
0.5	4.1	GO:0006986	response to unfolded protein(GO:0006986)
0.5	0.5	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.5	1.5	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.5	3.5	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.5	30.1	GO:0042742	defense response to bacterium(GO:0042742)
0.5	4.8	GO:0007602	phototransduction(GO:0007602)
0.5	1.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.5	11.1	GO:0008360	regulation of cell shape(GO:0008360)
0.5	0.5	GO:0043589	skin morphogenesis(GO:0043589)
0.5	2.3	GO:0030101	natural killer cell activation(GO:0030101)
0.5	4.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.5	3.6	GO:0008272	sulfate transport(GO:0008272)
0.4	0.9	GO:0033762	response to glucagon(GO:0033762)
0.4	0.4	GO:0010712	regulation of collagen metabolic process(GO:0010712)
0.4	2.6	GO:0030318	melanocyte differentiation(GO:0030318)
0.4	0.4	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.4	17.7	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.4	0.4	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
0.4	0.4	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.4	0.4	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.4	0.4	GO:0060536	cartilage morphogenesis(GO:0060536)
0.4	0.8	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.4	0.4	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.4	0.4	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4	3.5	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.4	14.5	GO:0050909	sensory perception of taste(GO:0050909)
0.4	0.4	GO:0009629	response to gravity(GO:0009629)
0.4	27.1	GO:0007265	Ras protein signal transduction(GO:0007265)
0.4	2.2	GO:0043616	keratinocyte proliferation(GO:0043616)
0.3	3.1	GO:0006721	terpenoid metabolic process(GO:0006721)
0.3	0.3	GO:0045924	regulation of female receptivity(GO:0045924)
0.3	1.0	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.3	1.0	GO:0007584	response to nutrient(GO:0007584)
0.3	0.7	GO:0045793	positive regulation of cell size(GO:0045793)
0.3	1.3	GO:0019724	B cell mediated immunity(GO:0019724)
0.3	8.7	GO:0006281	DNA repair(GO:0006281)
0.3	0.6	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3	0.3	GO:0060416	response to growth hormone(GO:0060416)
0.3	10.7	GO:0045087	innate immune response(GO:0045087)
0.3	0.6	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.3	0.9	GO:0036233	glycine import(GO:0036233)
0.3	0.3	GO:1901616	organic hydroxy compound catabolic process(GO:1901616)
0.3	0.6	GO:0018198	peptidyl-cysteine modification(GO:0018198)
0.3	0.3	GO:0018377	protein myristoylation(GO:0018377)
0.3	0.3	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.3	0.3	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.3	4.4	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.3	0.3	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.3	0.3	GO:0009597	detection of virus(GO:0009597)
0.2	0.2	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.2	0.5	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.2	2.3	GO:0001824	blastocyst development(GO:0001824)
0.2	0.7	GO:0046324	regulation of glucose import(GO:0046324)
0.2	0.7	GO:0031331	positive regulation of cellular catabolic process(GO:0031331)
0.2	0.9	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.2	0.2	GO:0008355	olfactory learning(GO:0008355)
0.2	8.2	GO:0008033	tRNA processing(GO:0008033)
0.2	7.6	GO:0019882	antigen processing and presentation(GO:0019882)
0.2	10.2	GO:0016568	chromatin modification(GO:0016568)
0.2	0.2	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.2	0.9	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2	0.5	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.2	2.1	GO:0015749	monosaccharide transport(GO:0015749)
0.2	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	0.6	GO:0048730	epidermis morphogenesis(GO:0048730)
0.2	15.8	GO:0019236	response to pheromone(GO:0019236)
0.1	0.6	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1	0.3	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	1.5	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	0.4	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	1.7	GO:0006006	glucose metabolic process(GO:0006006)
0.1	115.7	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
0.1	0.1	GO:0044033	multi-organism metabolic process(GO:0044033)
0.1	0.1	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.3	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.1	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	0.1	GO:0048569	post-embryonic organ development(GO:0048569)
0.1	0.3	GO:0007098	centrosome cycle(GO:0007098)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
30.7	153.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
21.0	63.1	GO:0005833	hemoglobin complex(GO:0005833)
21.0	21.0	GO:0031988	membrane-bounded vesicle(GO:0031988)
19.3	96.3	GO:0031094	platelet dense tubular network(GO:0031094)
17.0	84.8	GO:0033093	Weibel-Palade body(GO:0033093)
16.9	84.4	GO:0016461	unconventional myosin complex(GO:0016461)
16.2	64.6	GO:1990130	Iml1 complex(GO:1990130)
15.9	47.7	GO:0097443	sorting endosome(GO:0097443)
15.5	62.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
15.3	61.1	GO:0071141	SMAD protein complex(GO:0071141)
15.0	119.9	GO:0030056	hemidesmosome(GO:0030056)
15.0	74.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
14.8	59.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
14.8	14.8	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
14.7	44.2	GO:0036488	CHOP-C/EBP complex(GO:0036488)
12.6	63.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
12.6	50.4	GO:0030121	AP-1 adaptor complex(GO:0030121)
12.4	49.7	GO:0072487	MSL complex(GO:0072487)
12.2	12.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
12.1	36.4	GO:0097512	cardiac myofibril(GO:0097512)
11.9	35.8	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
11.7	128.5	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
11.7	35.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
11.4	22.8	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
11.4	56.8	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
11.3	22.7	GO:0060053	neurofilament cytoskeleton(GO:0060053)
11.3	34.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
11.3	22.7	GO:0031090	organelle membrane(GO:0031090)
11.3	90.1	GO:0005861	troponin complex(GO:0005861)
11.0	21.9	GO:0031523	Myb complex(GO:0031523)
10.8	32.5	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
10.4	31.1	GO:0046691	intracellular canaliculus(GO:0046691)
10.2	20.4	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
10.2	10.2	GO:0043679	axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
10.1	10.1	GO:0000322	storage vacuole(GO:0000322)
10.0	30.0	GO:0005610	laminin-5 complex(GO:0005610)
9.9	29.6	GO:0005588	collagen type V trimer(GO:0005588)
9.9	69.0	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
9.5	57.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
9.5	47.6	GO:0005638	lamin filament(GO:0005638)
9.2	18.4	GO:0031252	cell leading edge(GO:0031252)
9.2	9.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
9.1	91.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
9.0	9.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
8.6	8.6	GO:0005914	spot adherens junction(GO:0005914)
8.6	43.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
8.5	25.4	GO:0030125	clathrin vesicle coat(GO:0030125)
8.4	16.9	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
8.3	41.6	GO:0005927	muscle tendon junction(GO:0005927)
8.2	57.5	GO:0042382	paraspeckles(GO:0042382)
8.1	187.0	GO:0008305	integrin complex(GO:0008305)
8.1	40.6	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
8.0	24.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
8.0	47.9	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
7.9	31.8	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
7.9	637.7	GO:0030863	cortical cytoskeleton(GO:0030863)
7.8	85.8	GO:0031528	microvillus membrane(GO:0031528)
7.7	23.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
7.5	37.7	GO:0061617	MICOS complex(GO:0061617)
7.4	59.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
7.4	81.0	GO:0002102	podosome(GO:0002102)
7.3	29.4	GO:0030914	STAGA complex(GO:0030914)
7.3	7.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
7.3	51.3	GO:0005577	fibrinogen complex(GO:0005577)
7.3	51.2	GO:0005916	fascia adherens(GO:0005916)
7.3	95.0	GO:0043034	costamere(GO:0043034)
7.3	14.6	GO:0044292	dendrite terminus(GO:0044292)
7.2	7.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
7.2	21.6	GO:0097413	Lewy body(GO:0097413)
7.1	142.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
7.1	64.0	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
7.1	7.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141)
7.1	56.7	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
7.0	49.3	GO:0031931	TORC1 complex(GO:0031931)
7.0	21.1	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
7.0	21.0	GO:0031933	telomeric heterochromatin(GO:0031933)
7.0	307.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
7.0	41.9	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
6.9	20.7	GO:0097149	centralspindlin complex(GO:0097149)
6.7	20.0	GO:0033553	rDNA heterochromatin(GO:0033553)
6.7	13.4	GO:0097418	neurofibrillary tangle(GO:0097418)
6.6	33.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
6.6	13.2	GO:0031088	platelet dense granule membrane(GO:0031088)
6.5	19.5	GO:1990635	proximal dendrite(GO:1990635)
6.5	39.0	GO:0097470	ribbon synapse(GO:0097470)
6.5	6.5	GO:0097452	GAIT complex(GO:0097452)
6.5	45.4	GO:0045179	apical cortex(GO:0045179)
6.5	12.9	GO:0015629	actin cytoskeleton(GO:0015629)
6.4	25.8	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
6.4	57.9	GO:0097208	alveolar lamellar body(GO:0097208)
6.4	89.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
6.4	249.1	GO:0017053	transcriptional repressor complex(GO:0017053)
6.4	6.4	GO:0032133	chromosome passenger complex(GO:0032133)
6.4	50.8	GO:0042641	actomyosin(GO:0042641)
6.3	69.3	GO:0031430	M band(GO:0031430)
6.3	6.3	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
6.3	31.5	GO:0031298	replication fork protection complex(GO:0031298)
6.3	37.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
6.3	25.1	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
6.3	287.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
6.2	6.2	GO:0000815	ESCRT III complex(GO:0000815)
6.2	24.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
6.2	12.4	GO:0005828	kinetochore microtubule(GO:0005828)
6.2	36.9	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
6.1	12.3	GO:0045259	proton-transporting ATP synthase complex(GO:0045259)
6.1	24.3	GO:0097431	mitotic spindle pole(GO:0097431)
6.0	24.1	GO:1990246	uniplex complex(GO:1990246)
6.0	17.9	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
5.9	329.3	GO:0000118	histone deacetylase complex(GO:0000118)
5.8	17.5	GO:1990462	omegasome(GO:1990462)
5.8	173.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
5.8	40.5	GO:0001650	fibrillar center(GO:0001650)
5.8	98.1	GO:0031672	A band(GO:0031672)
5.8	11.5	GO:0030870	Mre11 complex(GO:0030870)
5.8	17.3	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
5.7	126.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
5.7	5.7	GO:0000346	transcription export complex(GO:0000346)
5.7	17.2	GO:0035189	Rb-E2F complex(GO:0035189)
5.6	5.6	GO:0034464	BBSome(GO:0034464)
5.6	61.7	GO:0035102	PRC1 complex(GO:0035102)
5.6	16.8	GO:1990423	RZZ complex(GO:1990423)
5.6	44.8	GO:0031010	ISWI-type complex(GO:0031010)
5.6	16.7	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
5.6	22.2	GO:0097524	sperm plasma membrane(GO:0097524)
5.6	105.6	GO:0000242	pericentriolar material(GO:0000242)
5.5	33.2	GO:0031932	TORC2 complex(GO:0031932)
5.5	11.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
5.5	5.5	GO:0000125	PCAF complex(GO:0000125)
5.5	22.0	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
5.5	16.5	GO:0005726	perichromatin fibrils(GO:0005726)
5.5	60.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
5.5	22.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
5.5	109.6	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
5.5	443.1	GO:0072562	blood microparticle(GO:0072562)
5.4	70.6	GO:0000974	Prp19 complex(GO:0000974)
5.4	21.7	GO:0071439	clathrin complex(GO:0071439)
5.4	5.4	GO:0032432	actin filament bundle(GO:0032432)
5.4	10.8	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
5.4	27.0	GO:0048476	Holliday junction resolvase complex(GO:0048476)
5.4	5.4	GO:0005686	U2 snRNP(GO:0005686)
5.3	26.7	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
5.3	47.8	GO:0035631	CD40 receptor complex(GO:0035631)
5.3	26.5	GO:0044613	nuclear pore central transport channel(GO:0044613)
5.3	21.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
5.3	36.9	GO:1990023	mitotic spindle midzone(GO:1990023)
5.2	109.9	GO:0035145	exon-exon junction complex(GO:0035145)
5.2	15.7	GO:0033596	TSC1-TSC2 complex(GO:0033596)
5.2	15.6	GO:0044316	cone cell pedicle(GO:0044316)
5.2	274.9	GO:0005811	lipid particle(GO:0005811)
5.1	15.4	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
5.1	20.4	GO:0035363	histone locus body(GO:0035363)
5.1	10.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
5.1	10.1	GO:0033263	CORVET complex(GO:0033263)
5.1	15.2	GO:0044194	cytolytic granule(GO:0044194)
5.1	45.5	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
5.0	15.1	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
5.0	35.2	GO:0031595	nuclear proteasome complex(GO:0031595)
5.0	85.4	GO:0045120	pronucleus(GO:0045120)
5.0	40.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
5.0	10.0	GO:0005579	membrane attack complex(GO:0005579)
5.0	69.8	GO:0010369	chromocenter(GO:0010369)
5.0	19.9	GO:0005677	chromatin silencing complex(GO:0005677)
5.0	24.8	GO:0031143	pseudopodium(GO:0031143)
5.0	9.9	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
4.9	39.5	GO:0042587	glycogen granule(GO:0042587)
4.9	24.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
4.9	14.7	GO:0042627	chylomicron(GO:0042627)
4.9	14.7	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
4.9	29.2	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
4.9	19.5	GO:0005775	vacuolar lumen(GO:0005775)
4.9	58.3	GO:0042589	zymogen granule membrane(GO:0042589)
4.8	29.1	GO:0005818	aster(GO:0005818)
4.8	4.8	GO:0044327	dendritic spine head(GO:0044327)
4.8	23.9	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
4.8	28.6	GO:0030915	Smc5-Smc6 complex(GO:0030915)
4.8	4.8	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
4.7	42.7	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
4.7	14.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
4.7	23.5	GO:0005663	DNA replication factor C complex(GO:0005663)
4.7	4.7	GO:0000439	core TFIIH complex(GO:0000439)
4.7	102.7	GO:0012505	endomembrane system(GO:0012505)
4.7	14.0	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
4.7	97.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
4.7	60.5	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
4.6	9.2	GO:1990923	PET complex(GO:1990923)
4.6	13.8	GO:0005642	annulate lamellae(GO:0005642)
4.6	27.5	GO:0016600	flotillin complex(GO:0016600)
4.6	13.8	GO:0070688	MLL5-L complex(GO:0070688)
4.6	22.9	GO:0042824	MHC class I peptide loading complex(GO:0042824)
4.6	251.9	GO:0016363	nuclear matrix(GO:0016363)
4.6	13.7	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
4.6	31.9	GO:0032593	insulin-responsive compartment(GO:0032593)
4.5	13.6	GO:0005879	axonemal microtubule(GO:0005879)
4.5	63.5	GO:1990204	oxidoreductase complex(GO:1990204)
4.5	4.5	GO:0033270	paranode region of axon(GO:0033270)
4.5	45.1	GO:0046581	intercellular canaliculus(GO:0046581)
4.5	13.4	GO:0071953	elastic fiber(GO:0071953)
4.5	13.4	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.5	22.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
4.5	22.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
4.4	26.6	GO:0043219	lateral loop(GO:0043219)
4.4	93.0	GO:0000786	nucleosome(GO:0000786)
4.4	8.8	GO:0043259	laminin-10 complex(GO:0043259)
4.4	70.6	GO:0000145	exocyst(GO:0000145)
4.4	52.8	GO:0071004	U2-type prespliceosome(GO:0071004)
4.4	39.2	GO:0002116	semaphorin receptor complex(GO:0002116)
4.4	26.1	GO:0033061	DNA recombinase mediator complex(GO:0033061)
4.3	1041.8	GO:0030055	cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
4.3	12.9	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
4.3	17.2	GO:0030689	Noc complex(GO:0030689)
4.3	17.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
4.3	80.9	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
4.2	17.0	GO:0005796	Golgi lumen(GO:0005796)
4.2	220.0	GO:0016605	PML body(GO:0016605)
4.2	16.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
4.2	12.6	GO:0070938	contractile ring(GO:0070938)
4.2	37.8	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
4.2	20.9	GO:0090543	Flemming body(GO:0090543)
4.2	12.5	GO:0097543	ciliary inversin compartment(GO:0097543)
4.1	8.3	GO:0016939	kinesin II complex(GO:0016939)
4.1	8.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
4.1	165.2	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
4.1	4.1	GO:0005652	nuclear lamina(GO:0005652)
4.1	53.3	GO:0005682	U5 snRNP(GO:0005682)
4.1	8.2	GO:0070765	gamma-secretase complex(GO:0070765)
4.1	89.6	GO:0030131	clathrin adaptor complex(GO:0030131)
4.1	308.5	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
4.0	40.5	GO:0070852	cell body fiber(GO:0070852)
4.0	137.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
4.0	68.0	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
4.0	59.9	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
3.9	15.8	GO:0035327	transcriptionally active chromatin(GO:0035327)
3.9	27.6	GO:0097539	ciliary transition fiber(GO:0097539)
3.9	71.0	GO:0034451	centriolar satellite(GO:0034451)
3.9	27.4	GO:0090544	BAF-type complex(GO:0090544)
3.9	101.9	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
3.9	31.3	GO:0044440	endosomal part(GO:0044440)
3.9	330.1	GO:0005903	brush border(GO:0005903)
3.9	11.6	GO:0043293	apoptosome(GO:0043293)
3.9	15.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
3.8	11.5	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
3.8	15.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
3.8	11.4	GO:0042612	MHC class I protein complex(GO:0042612)
3.8	3.8	GO:0042788	polysomal ribosome(GO:0042788)
3.8	34.2	GO:0005869	dynactin complex(GO:0005869)
3.8	22.7	GO:0031415	NatA complex(GO:0031415)
3.8	11.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
3.8	11.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
3.8	7.5	GO:0098536	deuterosome(GO:0098536)
3.8	15.1	GO:0032009	early phagosome(GO:0032009)
3.8	30.1	GO:0055037	recycling endosome(GO:0055037)
3.7	15.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
3.7	15.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
3.7	33.6	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
3.7	18.7	GO:0044232	organelle membrane contact site(GO:0044232)
3.7	22.3	GO:0042599	lamellar body(GO:0042599)
3.7	14.8	GO:0000938	GARP complex(GO:0000938)
3.7	7.4	GO:0030137	COPI-coated vesicle(GO:0030137)
3.7	3.7	GO:0070419	nonhomologous end joining complex(GO:0070419)
3.7	25.9	GO:0043020	NADPH oxidase complex(GO:0043020)
3.7	40.3	GO:0097225	sperm midpiece(GO:0097225)
3.7	11.0	GO:0033269	internode region of axon(GO:0033269)
3.6	47.4	GO:0005844	polysome(GO:0005844)
3.6	10.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
3.6	32.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
3.6	28.8	GO:0043196	varicosity(GO:0043196)
3.6	93.3	GO:0016592	mediator complex(GO:0016592)
3.6	50.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
3.6	21.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
3.6	28.6	GO:1990909	Wnt signalosome(GO:1990909)
3.6	28.4	GO:0031080	nuclear pore outer ring(GO:0031080)
3.5	49.7	GO:0031519	PcG protein complex(GO:0031519)
3.5	14.2	GO:0005827	polar microtubule(GO:0005827)
3.5	10.6	GO:0005683	U7 snRNP(GO:0005683)
3.5	77.8	GO:0008023	transcription elongation factor complex(GO:0008023)
3.5	77.8	GO:0035869	ciliary transition zone(GO:0035869)
3.5	31.6	GO:0031616	spindle pole centrosome(GO:0031616)
3.5	10.5	GO:0071817	MMXD complex(GO:0071817)
3.5	121.4	GO:0000123	histone acetyltransferase complex(GO:0000123)
3.5	10.4	GO:0005915	zonula adherens(GO:0005915)
3.5	141.6	GO:0000922	spindle pole(GO:0000922)
3.4	6.9	GO:0030132	clathrin coat of coated pit(GO:0030132)
3.4	10.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
3.4	174.4	GO:0000502	proteasome complex(GO:0000502)
3.4	20.4	GO:0008385	IkappaB kinase complex(GO:0008385)
3.4	27.2	GO:0017119	Golgi transport complex(GO:0017119)
3.4	10.2	GO:0019815	B cell receptor complex(GO:0019815)
3.4	13.5	GO:0005641	nuclear envelope lumen(GO:0005641)
3.4	6.7	GO:0005774	vacuolar membrane(GO:0005774)
3.4	23.5	GO:0042575	DNA polymerase complex(GO:0042575)
3.3	33.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
3.3	132.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
3.3	72.7	GO:0001750	photoreceptor outer segment(GO:0001750)
3.3	161.5	GO:0030496	midbody(GO:0030496)
3.3	3.3	GO:0035061	interchromatin granule(GO:0035061)
3.3	29.5	GO:0030014	CCR4-NOT complex(GO:0030014)
3.3	13.1	GO:0042629	mast cell granule(GO:0042629)
3.3	29.4	GO:0030904	retromer complex(GO:0030904)
3.3	26.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
3.3	32.5	GO:0005719	nuclear euchromatin(GO:0005719)
3.2	58.4	GO:0005876	spindle microtubule(GO:0005876)
3.2	113.1	GO:0005643	nuclear pore(GO:0005643)
3.2	128.7	GO:0016529	sarcoplasmic reticulum(GO:0016529)
3.2	54.6	GO:0001772	immunological synapse(GO:0001772)
3.2	9.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
3.2	6.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
3.2	9.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
3.2	623.3	GO:0005667	transcription factor complex(GO:0005667)
3.2	19.0	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
3.2	9.5	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
3.1	65.9	GO:0005771	multivesicular body(GO:0005771)
3.1	9.4	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
3.1	3.1	GO:1990716	axonemal central apparatus(GO:1990716)
3.1	6.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
3.1	99.0	GO:0016328	lateral plasma membrane(GO:0016328)
3.1	3.1	GO:0071203	WASH complex(GO:0071203)
3.1	3.1	GO:0061574	ASAP complex(GO:0061574)
3.1	9.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
3.0	336.8	GO:0031965	nuclear membrane(GO:0031965)
3.0	27.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
3.0	84.6	GO:0005776	autophagosome(GO:0005776)
3.0	9.0	GO:0042101	T cell receptor complex(GO:0042101)
3.0	51.0	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
3.0	9.0	GO:0046930	pore complex(GO:0046930)
3.0	14.8	GO:0097422	tubular endosome(GO:0097422)
3.0	23.6	GO:0036379	myofilament(GO:0036379)
2.9	5.9	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
2.9	5.9	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.9	5.8	GO:0097542	ciliary tip(GO:0097542)
2.9	11.6	GO:0034709	methylosome(GO:0034709)
2.9	17.4	GO:0042581	specific granule(GO:0042581)
2.9	23.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
2.8	17.0	GO:0030991	intraciliary transport particle A(GO:0030991)
2.8	17.0	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
2.8	19.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
2.8	62.3	GO:0016459	myosin complex(GO:0016459)
2.8	11.3	GO:0031091	platelet alpha granule(GO:0031091)
2.8	87.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
2.8	5.6	GO:0000814	ESCRT II complex(GO:0000814)
2.8	28.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
2.8	16.8	GO:0032591	dendritic spine membrane(GO:0032591)
2.8	289.0	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
2.7	46.7	GO:0045178	basal part of cell(GO:0045178)
2.7	62.9	GO:0030667	secretory granule membrane(GO:0030667)
2.7	24.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
2.7	275.5	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
2.7	48.7	GO:0097228	sperm principal piece(GO:0097228)
2.7	2.7	GO:0001652	granular component(GO:0001652)
2.7	66.7	GO:0045171	intercellular bridge(GO:0045171)
2.7	21.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
2.7	2916.5	GO:0005654	nucleoplasm(GO:0005654)
2.7	5.3	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
2.6	2.6	GO:0042827	platelet dense granule(GO:0042827)
2.6	2.6	GO:0071797	LUBAC complex(GO:0071797)
2.6	144.0	GO:0001726	ruffle(GO:0001726)
2.6	10.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
2.5	2.5	GO:0070545	PeBoW complex(GO:0070545)
2.5	7.6	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
2.5	7.6	GO:0031417	NatC complex(GO:0031417)
2.5	17.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
2.5	5.0	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
2.5	672.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
2.4	4.9	GO:0097255	R2TP complex(GO:0097255)
2.4	22.0	GO:0031083	BLOC-1 complex(GO:0031083)
2.4	78.1	GO:0000776	kinetochore(GO:0000776)
2.4	7.1	GO:0000243	commitment complex(GO:0000243)
2.4	460.1	GO:0005694	chromosome(GO:0005694)
2.4	7.1	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
2.4	4.7	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
2.3	32.6	GO:0030120	vesicle coat(GO:0030120)
2.3	3345.5	GO:0070062	extracellular exosome(GO:0070062)
2.3	2.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
2.3	6.8	GO:0031501	mannosyltransferase complex(GO:0031501)
2.2	33.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
2.2	2.2	GO:0071437	invadopodium(GO:0071437)
2.2	84.0	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
2.2	6.6	GO:0043197	dendritic spine(GO:0043197)
2.1	2.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
2.1	52.9	GO:0043231	intracellular membrane-bounded organelle(GO:0043231)
2.1	2.1	GO:0042405	nuclear inclusion body(GO:0042405)
2.1	6.2	GO:0089701	U2AF(GO:0089701)
2.1	2.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
2.0	2.0	GO:0005913	cell-cell adherens junction(GO:0005913)
2.0	48.4	GO:0005938	cell cortex(GO:0005938)
2.0	2.0	GO:0016342	catenin complex(GO:0016342)
2.0	162.0	GO:0005759	mitochondrial matrix(GO:0005759)
2.0	1120.6	GO:0005829	cytosol(GO:0005829)
1.9	7.8	GO:0070652	HAUS complex(GO:0070652)
1.9	3.9	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
1.9	7.8	GO:0032993	protein-DNA complex(GO:0032993)
1.9	3.9	GO:1990391	DNA repair complex(GO:1990391)
1.9	7.7	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
1.9	3.8	GO:0034457	Mpp10 complex(GO:0034457)
1.9	407.0	GO:0005730	nucleolus(GO:0005730)
1.9	31.9	GO:0005905	clathrin-coated pit(GO:0005905)
1.8	12.6	GO:0005902	microvillus(GO:0005902)
1.8	3.6	GO:0070069	cytochrome complex(GO:0070069)
1.8	8.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
1.8	7.0	GO:0035859	Seh1-associated complex(GO:0035859)
1.8	31.6	GO:0005901	caveola(GO:0005901)
1.7	3.4	GO:0005871	kinesin complex(GO:0005871)
1.7	1.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
1.7	889.3	GO:0005739	mitochondrion(GO:0005739)
1.7	33.7	GO:0005635	nuclear envelope(GO:0005635)
1.7	11.6	GO:0008180	COP9 signalosome(GO:0008180)
1.6	3.3	GO:0032584	growth cone membrane(GO:0032584)
1.6	6.4	GO:0031512	motile primary cilium(GO:0031512)
1.6	1.6	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
1.6	35.0	GO:0005795	Golgi stack(GO:0005795)
1.6	3.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
1.5	75.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
1.5	4.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
1.5	4.5	GO:0072372	primary cilium(GO:0072372)
1.5	29.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
1.5	20.7	GO:0036126	sperm flagellum(GO:0036126)
1.5	4.4	GO:0019898	extrinsic component of membrane(GO:0019898)
1.5	76.6	GO:0005681	spliceosomal complex(GO:0005681)
1.5	1.5	GO:0031975	envelope(GO:0031975)
1.5	27.8	GO:0045095	keratin filament(GO:0045095)
1.4	206.2	GO:0005815	microtubule organizing center(GO:0005815)
1.4	27.1	GO:0030139	endocytic vesicle(GO:0030139)
1.4	34.3	GO:0031514	motile cilium(GO:0031514)
1.4	2.8	GO:0030312	external encapsulating structure(GO:0030312)
1.4	797.2	GO:0005783	endoplasmic reticulum(GO:0005783)
1.4	5.4	GO:0016272	prefoldin complex(GO:0016272)
1.3	10.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.3	2.7	GO:0030008	TRAPP complex(GO:0030008)
1.3	3.9	GO:0005770	late endosome(GO:0005770)
1.3	5.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
1.2	13.3	GO:0005614	interstitial matrix(GO:0005614)
1.2	6.0	GO:0036157	outer dynein arm(GO:0036157)
1.2	7.2	GO:0043218	compact myelin(GO:0043218)
1.2	4.8	GO:0032426	stereocilium tip(GO:0032426)
1.2	7.2	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
1.2	37.5	GO:0098791	Golgi subcompartment(GO:0098791)
1.2	3.5	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
1.2	32.4	GO:0043292	contractile fiber(GO:0043292)
1.1	2.3	GO:0072687	meiotic spindle(GO:0072687)
1.1	153.4	GO:0009897	external side of plasma membrane(GO:0009897)
1.1	5.5	GO:0005798	Golgi-associated vesicle(GO:0005798)
1.1	46.0	GO:0005581	collagen trimer(GO:0005581)
1.1	2.1	GO:0070578	RISC-loading complex(GO:0070578)
1.0	2.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.0	3.0	GO:0030027	lamellipodium(GO:0030027)
1.0	1550.4	GO:0005634	nucleus(GO:0005634)
0.9	13.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.9	38.9	GO:0005769	early endosome(GO:0005769)
0.8	81.0	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.8	16.9	GO:0005882	intermediate filament(GO:0005882)
0.7	29.1	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.7	10.8	GO:0005922	connexon complex(GO:0005922)
0.6	7.0	GO:0009986	cell surface(GO:0009986)
0.6	26.9	GO:0016323	basolateral plasma membrane(GO:0016323)
0.5	10.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.5	243.6	GO:0005615	extracellular space(GO:0005615)
0.4	224.3	GO:0005576	extracellular region(GO:0005576)
0.3	1.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	2.3	GO:0030286	dynein complex(GO:0030286)
0.2	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	0.2	GO:0036128	CatSper complex(GO:0036128)
0.2	0.4	GO:0001533	cornified envelope(GO:0001533)
0.2	0.7	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.1	148.2	GO:0005737	cytoplasm(GO:0005737)
0.1	0.1	GO:0030057	desmosome(GO:0030057)
0.1	130.3	GO:0016021	integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
32.2	128.7	GO:0031720	haptoglobin binding(GO:0031720)
24.3	170.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
21.4	42.8	GO:0031721	hemoglobin alpha binding(GO:0031721)
20.9	62.6	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
20.8	104.2	GO:0051525	NFAT protein binding(GO:0051525)
20.5	82.0	GO:0009374	biotin binding(GO:0009374)
20.0	59.9	GO:0004687	myosin light chain kinase activity(GO:0004687)
19.6	58.8	GO:0070644	vitamin D response element binding(GO:0070644)
18.9	75.4	GO:0070053	thrombospondin receptor activity(GO:0070053)
18.7	56.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
18.3	54.8	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
17.6	52.7	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
17.5	104.8	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
16.7	66.8	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
16.4	65.5	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
16.2	129.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
14.8	59.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
14.7	44.2	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
14.3	57.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
13.8	13.8	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
13.7	41.1	GO:0030172	troponin C binding(GO:0030172)
13.7	13.7	GO:0032794	GTPase activating protein binding(GO:0032794)
13.3	13.3	GO:0042296	ISG15 transferase activity(GO:0042296)
13.1	156.8	GO:0017166	vinculin binding(GO:0017166)
13.1	39.2	GO:0050692	DBD domain binding(GO:0050692)
12.9	51.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
12.5	25.0	GO:0070573	metallodipeptidase activity(GO:0070573)
12.5	37.5	GO:0031711	bradykinin receptor binding(GO:0031711)
12.3	37.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
12.3	49.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
11.9	23.8	GO:0070538	oleic acid binding(GO:0070538)
11.9	35.7	GO:0004771	sterol esterase activity(GO:0004771)
11.8	47.3	GO:0015232	heme transporter activity(GO:0015232)
11.7	35.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
11.6	46.3	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
11.6	11.6	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
11.5	69.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
11.5	57.5	GO:0030274	LIM domain binding(GO:0030274)
11.4	45.7	GO:0005344	oxygen transporter activity(GO:0005344)
11.4	45.5	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
11.3	22.6	GO:0031871	proteinase activated receptor binding(GO:0031871)
11.2	33.6	GO:0005350	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
11.0	33.0	GO:0031014	troponin T binding(GO:0031014)
10.9	152.9	GO:0008307	structural constituent of muscle(GO:0008307)
10.8	32.4	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
10.7	75.0	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
10.7	32.1	GO:0004064	arylesterase activity(GO:0004064)
10.6	42.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
10.6	201.7	GO:0046965	retinoid X receptor binding(GO:0046965)
10.6	31.8	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
10.5	41.9	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
10.4	41.8	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
10.4	31.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
10.4	62.4	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
10.3	41.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
10.3	30.9	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
10.2	82.0	GO:0008430	selenium binding(GO:0008430)
10.2	30.6	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
10.2	50.9	GO:0009378	four-way junction helicase activity(GO:0009378)
10.2	61.0	GO:0001727	lipid kinase activity(GO:0001727)
10.1	40.3	GO:0004046	aminoacylase activity(GO:0004046)
10.1	80.5	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
10.0	20.1	GO:0048408	epidermal growth factor binding(GO:0048408)
10.0	10.0	GO:0034618	arginine binding(GO:0034618)
10.0	109.7	GO:0030898	actin-dependent ATPase activity(GO:0030898)
9.9	29.8	GO:0034186	apolipoprotein A-I binding(GO:0034186)
9.9	19.8	GO:0031013	troponin I binding(GO:0031013)
9.9	19.8	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
9.8	59.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
9.8	29.5	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
9.8	19.5	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
9.8	39.1	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
9.8	29.3	GO:0045134	uridine-diphosphatase activity(GO:0045134)
9.8	9.8	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
9.7	87.0	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
9.7	48.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
9.5	76.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
9.4	47.1	GO:0016841	ammonia-lyase activity(GO:0016841)
9.4	56.2	GO:0008199	ferric iron binding(GO:0008199)
9.3	18.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
9.3	28.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
9.3	27.9	GO:0019871	sodium channel inhibitor activity(GO:0019871)
9.2	27.7	GO:0004832	valine-tRNA ligase activity(GO:0004832)
9.2	73.8	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
9.2	27.5	GO:0004949	cannabinoid receptor activity(GO:0004949)
9.2	109.9	GO:0044548	S100 protein binding(GO:0044548)
9.1	36.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
9.0	45.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
9.0	81.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
9.0	17.9	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
9.0	17.9	GO:0042809	vitamin D receptor binding(GO:0042809)
8.9	62.3	GO:0019966	interleukin-1 binding(GO:0019966)
8.9	26.6	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
8.9	88.7	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
8.8	35.3	GO:0004305	ethanolamine kinase activity(GO:0004305)
8.8	53.0	GO:0031432	titin binding(GO:0031432)
8.8	35.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
8.8	35.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
8.8	123.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
8.7	34.7	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
8.6	77.4	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
8.6	34.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
8.6	34.2	GO:0031493	nucleosomal histone binding(GO:0031493)
8.5	76.8	GO:0015254	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
8.5	8.5	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
8.5	59.2	GO:0018653	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
8.3	33.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
8.3	91.0	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
8.3	16.5	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
8.3	8.3	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
8.2	24.6	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
8.2	32.7	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
8.1	73.0	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
8.0	40.1	GO:0015288	porin activity(GO:0015288)
8.0	24.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
8.0	40.0	GO:0070061	fructose binding(GO:0070061)
8.0	71.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
8.0	95.6	GO:0070300	phosphatidic acid binding(GO:0070300)
7.9	23.8	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
7.9	31.7	GO:0016833	oxo-acid-lyase activity(GO:0016833)
7.9	86.9	GO:0043024	ribosomal small subunit binding(GO:0043024)
7.8	39.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
7.8	47.0	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
7.8	31.1	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
7.8	23.3	GO:0019960	C-X3-C chemokine binding(GO:0019960)
7.8	15.5	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
7.7	61.9	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
7.7	38.7	GO:0004668	protein-arginine deiminase activity(GO:0004668)
7.7	107.7	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
7.7	84.4	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
7.6	7.6	GO:0005138	interleukin-6 receptor binding(GO:0005138)
7.6	45.6	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
7.6	30.3	GO:0015057	thrombin receptor activity(GO:0015057)
7.6	121.0	GO:0008143	poly(A) binding(GO:0008143)
7.5	15.1	GO:0015250	water channel activity(GO:0015250)
7.5	30.1	GO:0005534	galactose binding(GO:0005534)
7.5	97.7	GO:0008432	JUN kinase binding(GO:0008432)
7.5	22.5	GO:0008142	oxysterol binding(GO:0008142)
7.5	30.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
7.4	14.9	GO:0015928	fucosidase activity(GO:0015928)
7.4	29.7	GO:1990715	mRNA CDS binding(GO:1990715)
7.4	22.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
7.3	22.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
7.3	21.9	GO:0019770	IgG receptor activity(GO:0019770)
7.3	21.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
7.3	159.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
7.3	21.8	GO:0019961	interferon binding(GO:0019961)
7.3	14.5	GO:0002094	polyprenyltransferase activity(GO:0002094)
7.2	137.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
7.2	7.2	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
7.2	64.7	GO:0018449	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
7.1	7.1	GO:0019808	polyamine binding(GO:0019808)
7.1	21.4	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
7.1	14.2	GO:0051434	BH3 domain binding(GO:0051434)
7.1	35.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
7.1	56.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
7.1	63.6	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
7.0	63.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
7.0	105.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
7.0	21.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
7.0	28.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
7.0	76.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
7.0	21.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
6.9	27.6	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
6.9	20.6	GO:0030492	hemoglobin binding(GO:0030492)
6.9	20.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
6.9	13.7	GO:0035877	death effector domain binding(GO:0035877)
6.9	13.7	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
6.8	34.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
6.8	40.9	GO:0004311	farnesyltranstransferase activity(GO:0004311)
6.8	102.0	GO:0017049	GTP-Rho binding(GO:0017049)
6.8	20.4	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
6.8	33.9	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
6.7	6.7	GO:0030792	methylarsonite methyltransferase activity(GO:0030792)
6.7	26.7	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
6.7	59.9	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
6.6	33.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
6.6	13.3	GO:0016748	succinyltransferase activity(GO:0016748) N-succinyltransferase activity(GO:0016749)
6.6	13.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
6.6	13.2	GO:0031752	D5 dopamine receptor binding(GO:0031752)
6.6	19.7	GO:0030350	iron-responsive element binding(GO:0030350)
6.6	26.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
6.5	65.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
6.5	32.7	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
6.5	19.6	GO:0035276	alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276)
6.5	19.5	GO:0055100	adiponectin binding(GO:0055100)
6.5	12.9	GO:0019957	C-C chemokine binding(GO:0019957)
6.5	12.9	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
6.5	19.4	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
6.4	19.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
6.4	19.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
6.4	25.6	GO:0004127	cytidylate kinase activity(GO:0004127)
6.4	32.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
6.4	12.8	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
6.4	19.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
6.4	31.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
6.3	57.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
6.3	38.1	GO:0097322	7SK snRNA binding(GO:0097322)
6.3	38.0	GO:0004630	phospholipase D activity(GO:0004630)
6.3	88.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
6.3	25.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
6.3	25.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
6.3	6.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
6.3	25.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
6.3	25.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
6.3	56.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
6.2	6.2	GO:0005372	water transmembrane transporter activity(GO:0005372)
6.2	6.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
6.1	67.2	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
6.1	116.0	GO:0031492	nucleosomal DNA binding(GO:0031492)
6.1	73.0	GO:0005542	folic acid binding(GO:0005542)
6.0	42.3	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
6.0	24.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
6.0	6.0	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
6.0	36.0	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
6.0	12.0	GO:0008172	S-methyltransferase activity(GO:0008172)
6.0	12.0	GO:0043559	insulin binding(GO:0043559)
6.0	12.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
6.0	41.7	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
5.9	29.5	GO:0031749	D2 dopamine receptor binding(GO:0031749)
5.9	5.9	GO:0048030	disaccharide binding(GO:0048030)
5.9	5.9	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
5.9	23.4	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
5.8	29.2	GO:0017081	chloride channel regulator activity(GO:0017081)
5.8	23.3	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
5.8	5.8	GO:0043008	ATP-dependent protein binding(GO:0043008)
5.8	23.1	GO:0043515	kinetochore binding(GO:0043515)
5.8	17.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
5.8	17.3	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
5.7	23.0	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
5.7	17.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
5.7	165.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
5.6	16.9	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
5.6	33.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
5.6	5.6	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
5.6	55.9	GO:0004016	adenylate cyclase activity(GO:0004016)
5.6	11.2	GO:0016208	AMP binding(GO:0016208)
5.6	50.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
5.6	22.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
5.6	22.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
5.5	16.6	GO:0042731	PH domain binding(GO:0042731)
5.5	115.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
5.5	160.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
5.5	16.5	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
5.5	11.0	GO:0030519	snoRNP binding(GO:0030519)
5.5	33.0	GO:0003993	acid phosphatase activity(GO:0003993)
5.5	44.0	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
5.5	16.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
5.5	21.9	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
5.5	21.9	GO:0005047	signal recognition particle binding(GO:0005047)
5.5	43.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
5.4	10.9	GO:0016803	ether hydrolase activity(GO:0016803)
5.4	5.4	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
5.4	21.7	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
5.4	97.3	GO:0019206	nucleoside kinase activity(GO:0019206)
5.4	5.4	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
5.4	10.8	GO:0033142	progesterone receptor binding(GO:0033142)
5.4	10.8	GO:0001069	regulatory region RNA binding(GO:0001069)
5.4	91.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
5.4	21.5	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
5.4	21.5	GO:0034549	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
5.4	16.1	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
5.4	32.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
5.3	26.7	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
5.3	37.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
5.3	21.3	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
5.3	80.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
5.3	5.3	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
5.3	133.1	GO:0043236	laminin binding(GO:0043236)
5.3	26.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
5.3	15.9	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
5.3	26.4	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
5.3	21.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
5.3	26.3	GO:0042974	retinoic acid receptor binding(GO:0042974)
5.3	73.5	GO:0005521	lamin binding(GO:0005521)
5.2	21.0	GO:0042015	interleukin-20 binding(GO:0042015)
5.2	10.5	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
5.2	47.1	GO:0070568	guanylyltransferase activity(GO:0070568)
5.2	130.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
5.2	5.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
5.2	26.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
5.2	88.5	GO:0008483	transaminase activity(GO:0008483)
5.2	5.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
5.2	26.0	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
5.2	5.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
5.2	31.1	GO:0019825	oxygen binding(GO:0019825)
5.2	20.7	GO:0003696	satellite DNA binding(GO:0003696)
5.2	51.6	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
5.1	15.4	GO:0061665	SUMO ligase activity(GO:0061665)
5.1	5.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
5.1	25.5	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
5.1	20.4	GO:0019788	NEDD8 transferase activity(GO:0019788)
5.1	25.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
5.1	15.3	GO:0072542	protein phosphatase activator activity(GO:0072542)
5.1	15.2	GO:0035184	histone threonine kinase activity(GO:0035184)
5.1	45.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
5.1	10.1	GO:0070698	type I activin receptor binding(GO:0070698)
5.1	81.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
5.1	35.4	GO:0046790	virion binding(GO:0046790)
5.1	20.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
5.1	15.2	GO:0034452	dynactin binding(GO:0034452)
5.1	30.3	GO:0008420	CTD phosphatase activity(GO:0008420)
5.1	20.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
5.0	50.5	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
5.0	10.1	GO:0038132	neuregulin binding(GO:0038132)
5.0	45.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
5.0	5.0	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
5.0	25.1	GO:0034046	poly(G) binding(GO:0034046)
5.0	120.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
5.0	29.9	GO:0030983	mismatched DNA binding(GO:0030983)
5.0	19.9	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
5.0	19.8	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
4.9	59.2	GO:0010181	FMN binding(GO:0010181)
4.9	19.7	GO:0030984	kininogen binding(GO:0030984)
4.9	19.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
4.9	39.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
4.9	39.1	GO:0001222	transcription corepressor binding(GO:0001222)
4.9	44.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
4.9	9.8	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
4.9	24.4	GO:1990239	steroid hormone binding(GO:1990239)
4.8	43.6	GO:0005123	death receptor binding(GO:0005123)
4.8	82.0	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
4.8	62.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
4.8	14.4	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
4.8	81.5	GO:0017025	TBP-class protein binding(GO:0017025)
4.8	86.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
4.8	23.9	GO:0005536	glucose binding(GO:0005536)
4.8	14.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
4.8	4.8	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
4.8	19.1	GO:0035325	Toll-like receptor binding(GO:0035325)
4.8	19.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
4.8	42.9	GO:0001055	RNA polymerase II activity(GO:0001055)
4.8	28.6	GO:0030346	protein phosphatase 2B binding(GO:0030346)
4.7	9.5	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
4.7	9.5	GO:0000405	bubble DNA binding(GO:0000405)
4.7	14.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
4.7	23.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
4.7	51.8	GO:0045294	alpha-catenin binding(GO:0045294)
4.7	14.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
4.7	9.4	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
4.7	47.0	GO:0035497	cAMP response element binding(GO:0035497)
4.7	23.5	GO:0097642	calcitonin family receptor activity(GO:0097642)
4.7	37.5	GO:0042299	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
4.7	46.9	GO:0001530	lipopolysaccharide binding(GO:0001530)
4.7	23.4	GO:0046624	sphingolipid transporter activity(GO:0046624)
4.7	51.5	GO:0032183	SUMO binding(GO:0032183)
4.7	9.3	GO:0004126	cytidine deaminase activity(GO:0004126)
4.7	9.3	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
4.7	4.7	GO:0017098	sulfonylurea receptor binding(GO:0017098)
4.7	14.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
4.7	14.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
4.7	32.6	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
4.6	32.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
4.6	18.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
4.6	13.9	GO:0002060	purine nucleobase binding(GO:0002060)
4.6	59.9	GO:0050681	androgen receptor binding(GO:0050681)
4.6	13.8	GO:1990460	leptin receptor binding(GO:1990460)
4.6	13.8	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
4.6	36.8	GO:0017154	semaphorin receptor activity(GO:0017154)
4.6	9.2	GO:0070569	uridylyltransferase activity(GO:0070569)
4.6	27.5	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
4.6	68.6	GO:0015238	drug transmembrane transporter activity(GO:0015238)
4.5	31.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
4.5	4.5	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
4.5	49.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
4.5	13.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
4.5	13.5	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
4.5	22.5	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
4.5	4.5	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
4.5	98.9	GO:0045502	dynein binding(GO:0045502)
4.5	13.5	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
4.5	9.0	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
4.5	49.0	GO:0000400	four-way junction DNA binding(GO:0000400)
4.4	8.9	GO:0031404	chloride ion binding(GO:0031404)
4.4	4.4	GO:0002054	nucleobase binding(GO:0002054)
4.4	13.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
4.4	8.9	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
4.4	26.6	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
4.4	17.7	GO:0070492	oligosaccharide binding(GO:0070492)
4.4	30.9	GO:0018855	acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
4.4	22.0	GO:0005499	vitamin D binding(GO:0005499)
4.4	17.6	GO:0047372	acylglycerol lipase activity(GO:0047372)
4.3	60.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
4.3	13.0	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
4.3	21.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
4.3	8.5	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
4.2	8.5	GO:0043842	Kdo transferase activity(GO:0043842)
4.2	21.2	GO:0008494	translation activator activity(GO:0008494)
4.2	38.2	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
4.2	25.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
4.2	12.7	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
4.2	38.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
4.2	76.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
4.2	12.6	GO:0080084	RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
4.2	8.4	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
4.2	16.9	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
4.2	25.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
4.2	29.5	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
4.2	4.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
4.2	16.8	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
4.2	16.8	GO:0003680	AT DNA binding(GO:0003680)
4.2	29.2	GO:0019789	SUMO transferase activity(GO:0019789)
4.2	37.5	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
4.2	49.9	GO:0001784	phosphotyrosine binding(GO:0001784)
4.1	33.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
4.1	12.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
4.1	37.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
4.1	24.7	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
4.1	37.0	GO:0097602	cullin family protein binding(GO:0097602)
4.1	41.0	GO:0070412	R-SMAD binding(GO:0070412)
4.1	24.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
4.1	16.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
4.1	49.0	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
4.1	32.5	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
4.0	4.0	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
4.0	16.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
4.0	4.0	GO:0070034	telomerase RNA binding(GO:0070034)
4.0	40.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
4.0	16.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
4.0	24.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
4.0	4.0	GO:1904680	oligopeptide transmembrane transporter activity(GO:0035673) peptide transmembrane transporter activity(GO:1904680)
4.0	27.9	GO:0001846	opsonin binding(GO:0001846)
4.0	91.7	GO:0008536	Ran GTPase binding(GO:0008536)
4.0	8.0	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
4.0	55.7	GO:0000993	RNA polymerase II core binding(GO:0000993)
4.0	31.8	GO:0031996	thioesterase binding(GO:0031996)
4.0	11.9	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
4.0	15.9	GO:0031419	cobalamin binding(GO:0031419)
4.0	15.8	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
3.9	15.8	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.9	11.8	GO:0051734	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) ATP-dependent polynucleotide kinase activity(GO:0051734)
3.9	11.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
3.9	23.6	GO:0016004	phospholipase activator activity(GO:0016004)
3.9	46.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
3.9	144.5	GO:0070491	repressing transcription factor binding(GO:0070491)
3.9	15.6	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
3.9	11.7	GO:0005128	erythropoietin receptor binding(GO:0005128)
3.9	120.8	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
3.9	299.5	GO:0002020	protease binding(GO:0002020)
3.9	23.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
3.9	19.4	GO:0008097	5S rRNA binding(GO:0008097)
3.9	50.5	GO:0017091	AU-rich element binding(GO:0017091)
3.9	34.8	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
3.9	23.2	GO:0008131	primary amine oxidase activity(GO:0008131)
3.8	26.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
3.8	11.5	GO:0019862	IgA binding(GO:0019862)
3.8	68.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
3.8	15.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
3.8	11.3	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
3.8	3.8	GO:0004518	nuclease activity(GO:0004518)
3.8	3.8	GO:0004096	catalase activity(GO:0004096)
3.7	33.7	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
3.7	37.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
3.7	89.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
3.7	18.6	GO:0043522	leucine zipper domain binding(GO:0043522)
3.7	63.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
3.7	11.1	GO:0035514	DNA demethylase activity(GO:0035514)
3.7	7.4	GO:1990188	euchromatin binding(GO:1990188)
3.7	44.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
3.7	11.1	GO:0071253	connexin binding(GO:0071253)
3.7	25.8	GO:0051010	microtubule plus-end binding(GO:0051010)
3.7	11.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
3.7	36.8	GO:0070063	RNA polymerase binding(GO:0070063)
3.7	14.7	GO:0031491	nucleosome binding(GO:0031491)
3.7	29.4	GO:0017070	U6 snRNA binding(GO:0017070)
3.7	18.3	GO:0050700	CARD domain binding(GO:0050700)
3.7	153.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
3.7	69.6	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
3.6	7.3	GO:0016413	O-acetyltransferase activity(GO:0016413)
3.6	40.1	GO:0015643	toxic substance binding(GO:0015643)
3.6	116.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
3.6	10.9	GO:0000182	rDNA binding(GO:0000182)
3.6	21.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
3.6	7.3	GO:0051787	misfolded protein binding(GO:0051787)
3.6	72.4	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
3.6	10.9	GO:0004359	glutaminase activity(GO:0004359)
3.6	10.8	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
3.6	169.4	GO:0016836	hydro-lyase activity(GO:0016836)
3.6	326.7	GO:0017137	Rab GTPase binding(GO:0017137)
3.6	7.2	GO:0055102	lipase inhibitor activity(GO:0055102)
3.6	110.8	GO:0051723	protein methylesterase activity(GO:0051723)
3.6	10.7	GO:0071209	U7 snRNA binding(GO:0071209)
3.6	156.7	GO:0035326	enhancer binding(GO:0035326)
3.6	17.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
3.6	60.5	GO:0042826	histone deacetylase binding(GO:0042826)
3.5	74.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
3.5	10.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
3.5	24.7	GO:0050321	tau-protein kinase activity(GO:0050321)
3.5	21.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
3.5	21.1	GO:0017127	cholesterol transporter activity(GO:0017127)
3.5	3.5	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
3.5	129.5	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
3.5	14.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
3.5	24.4	GO:0070402	NADPH binding(GO:0070402)
3.5	59.0	GO:0003746	translation elongation factor activity(GO:0003746)
3.5	55.5	GO:0030544	Hsp70 protein binding(GO:0030544)
3.5	76.0	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
3.4	17.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
3.4	6.9	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
3.4	3.4	GO:0008425	C-methyltransferase activity(GO:0008169) 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity(GO:0008425) quinone cofactor methyltransferase activity(GO:0030580)
3.4	10.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
3.4	6.8	GO:0004645	phosphorylase activity(GO:0004645)
3.4	30.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.4	201.2	GO:0005178	integrin binding(GO:0005178)
3.4	10.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
3.4	10.2	GO:0019002	GMP binding(GO:0019002)
3.4	3.4	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
3.4	13.5	GO:0043274	phospholipase binding(GO:0043274)
3.4	23.7	GO:0001848	complement binding(GO:0001848)
3.4	23.6	GO:0031369	translation initiation factor binding(GO:0031369)
3.4	279.1	GO:0042393	histone binding(GO:0042393)
3.4	50.3	GO:0042162	telomeric DNA binding(GO:0042162)
3.3	6.7	GO:0005131	growth hormone receptor binding(GO:0005131)
3.3	3.3	GO:0043426	MRF binding(GO:0043426)
3.3	13.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
3.3	23.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
3.3	19.8	GO:0050733	RS domain binding(GO:0050733)
3.3	19.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
3.3	36.3	GO:0060590	ATPase activator activity(GO:0001671) ATPase regulator activity(GO:0060590)
3.3	82.2	GO:0008748	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
3.3	6.5	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
3.3	6.5	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
3.3	3.3	GO:0015923	mannosidase activity(GO:0015923)
3.2	25.9	GO:0001618	virus receptor activity(GO:0001618)
3.2	19.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
3.2	3.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
3.2	19.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
3.2	60.7	GO:0031593	polyubiquitin binding(GO:0031593)
3.2	16.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
3.2	9.6	GO:0000171	ribonuclease MRP activity(GO:0000171)
3.2	25.4	GO:0004806	triglyceride lipase activity(GO:0004806)
3.2	3.2	GO:0016428	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
3.2	22.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
3.1	6.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
3.1	18.9	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
3.1	3.1	GO:0019238	cyclohydrolase activity(GO:0019238)
3.1	18.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
3.1	3.1	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
3.1	12.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
3.1	9.4	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.1	18.7	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
3.1	15.6	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
3.1	401.6	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
3.1	6.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
3.1	15.5	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
3.1	3.1	GO:0042054	histone methyltransferase activity(GO:0042054)
3.1	89.7	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
3.1	6.2	GO:0019107	myristoyltransferase activity(GO:0019107)
3.1	6.2	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
3.1	3.1	GO:0070728	leucine binding(GO:0070728)
3.1	92.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
3.1	9.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
3.1	9.2	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
3.1	33.8	GO:0030881	beta-2-microglobulin binding(GO:0030881)
3.1	12.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
3.1	9.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
3.0	91.3	GO:0003684	damaged DNA binding(GO:0003684)
3.0	94.1	GO:0005132	type I interferon receptor binding(GO:0005132)
3.0	9.1	GO:0035671	enone reductase activity(GO:0035671)
3.0	63.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
3.0	69.4	GO:0032182	ubiquitin-like protein binding(GO:0032182)
3.0	11.9	GO:0004407	histone deacetylase activity(GO:0004407)
3.0	59.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
3.0	59.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
3.0	5.9	GO:0019213	deacetylase activity(GO:0019213)
3.0	62.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
3.0	3.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
3.0	204.3	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
3.0	23.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
2.9	26.5	GO:0004568	chitinase activity(GO:0004568)
2.9	11.8	GO:0004966	galanin receptor activity(GO:0004966)
2.9	5.9	GO:1990825	sequence-specific mRNA binding(GO:1990825)
2.9	14.7	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
2.9	26.4	GO:0001221	transcription cofactor binding(GO:0001221)
2.9	102.6	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
2.9	52.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
2.9	2.9	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
2.9	64.4	GO:0048487	beta-tubulin binding(GO:0048487)
2.9	20.5	GO:0070567	cytidylyltransferase activity(GO:0070567)
2.9	5.8	GO:0043495	protein anchor(GO:0043495)
2.9	141.5	GO:0008135	translation factor activity, RNA binding(GO:0008135)
2.9	112.6	GO:0031072	heat shock protein binding(GO:0031072)
2.9	94.9	GO:0003697	single-stranded DNA binding(GO:0003697)
2.9	8.6	GO:0016842	amidine-lyase activity(GO:0016842)
2.9	11.4	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.9	5.7	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
2.8	11.4	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
2.8	2.8	GO:0071987	WD40-repeat domain binding(GO:0071987)
2.8	8.5	GO:0004461	lactose synthase activity(GO:0004461)
2.8	264.8	GO:0016881	acid-amino acid ligase activity(GO:0016881)
2.8	2.8	GO:0036122	BMP binding(GO:0036122)
2.8	19.6	GO:0001054	RNA polymerase I activity(GO:0001054)
2.8	22.3	GO:0015245	fatty acid transporter activity(GO:0015245)
2.8	11.2	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
2.8	25.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.8	72.0	GO:0005507	copper ion binding(GO:0005507)
2.8	2.8	GO:0017108	5'-flap endonuclease activity(GO:0017108)
2.7	11.0	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
2.7	76.9	GO:0016830	carbon-carbon lyase activity(GO:0016830)
2.7	8.2	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
2.7	193.9	GO:0017124	SH3 domain binding(GO:0017124)
2.7	13.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
2.7	16.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
2.7	24.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
2.7	2.7	GO:0008318	protein prenyltransferase activity(GO:0008318)
2.7	18.9	GO:0005523	tropomyosin binding(GO:0005523)
2.7	2.7	GO:0016436	rRNA methyltransferase activity(GO:0008649) rRNA (uridine) methyltransferase activity(GO:0016436)
2.7	67.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
2.7	8.0	GO:1990932	5.8S rRNA binding(GO:1990932)
2.7	37.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
2.7	34.7	GO:0051059	NF-kappaB binding(GO:0051059)
2.7	179.0	GO:0003880	protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
2.7	10.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
2.7	8.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
2.7	13.3	GO:0070628	proteasome binding(GO:0070628)
2.7	31.8	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
2.6	457.6	GO:0008134	transcription factor binding(GO:0008134)
2.6	7.9	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
2.6	13.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.6	86.7	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
2.6	10.5	GO:0043014	alpha-tubulin binding(GO:0043014)
2.6	23.5	GO:0034946	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
2.6	23.4	GO:0015605	nucleotide transmembrane transporter activity(GO:0015215) organophosphate ester transmembrane transporter activity(GO:0015605)
2.6	7.8	GO:0004385	guanylate kinase activity(GO:0004385)
2.6	10.4	GO:0034584	piRNA binding(GO:0034584)
2.6	10.4	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
2.6	7.8	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
2.6	49.1	GO:0043621	protein self-association(GO:0043621)
2.6	25.7	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
2.5	25.4	GO:0003785	actin monomer binding(GO:0003785)
2.5	2.5	GO:0016015	morphogen activity(GO:0016015)
2.5	12.7	GO:0008174	mRNA methyltransferase activity(GO:0008174)
2.5	7.5	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.5	5.0	GO:0010997	anaphase-promoting complex binding(GO:0010997)
2.5	2.5	GO:0038181	bile acid receptor activity(GO:0038181)
2.5	7.5	GO:0038100	nodal binding(GO:0038100)
2.5	12.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.5	7.4	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
2.4	12.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.4	2.4	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
2.4	12.2	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
2.4	28.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
2.4	23.9	GO:0001056	RNA polymerase III activity(GO:0001056)
2.4	9.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.4	128.6	GO:0003713	transcription coactivator activity(GO:0003713)
2.4	7.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
2.3	65.4	GO:0005484	SNAP receptor activity(GO:0005484)
2.3	7.0	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
2.3	4.7	GO:0051185	coenzyme transporter activity(GO:0051185)
2.3	13.8	GO:0071837	HMG box domain binding(GO:0071837)
2.3	4.6	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.3	11.5	GO:1990405	protein antigen binding(GO:1990405)
2.3	11.5	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
2.3	9.2	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
2.3	55.1	GO:0016417	S-acyltransferase activity(GO:0016417)
2.3	6.9	GO:0032036	myosin heavy chain binding(GO:0032036)
2.3	96.1	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
2.3	77.5	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812)
2.3	9.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
2.3	90.6	GO:0017048	Rho GTPase binding(GO:0017048)
2.3	2.3	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
2.3	4.5	GO:2001070	starch binding(GO:2001070)
2.3	2.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
2.2	11.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.2	2.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
2.2	13.2	GO:0001595	angiotensin receptor activity(GO:0001595)
2.2	17.6	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
2.2	269.0	GO:0005096	GTPase activator activity(GO:0005096)
2.2	6.5	GO:0034511	U3 snoRNA binding(GO:0034511)
2.2	6.5	GO:0000146	microfilament motor activity(GO:0000146)
2.2	6.5	GO:0034062	RNA polymerase activity(GO:0034062)
2.1	49.4	GO:0015485	cholesterol binding(GO:0015485)
2.1	25.7	GO:0022829	wide pore channel activity(GO:0022829)
2.1	17.1	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
2.1	2.1	GO:0031433	telethonin binding(GO:0031433)
2.1	124.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
2.1	10.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
2.1	40.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.1	4.2	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
2.1	16.8	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
2.1	8.4	GO:0000104	succinate dehydrogenase activity(GO:0000104)
2.1	195.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
2.1	58.8	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.1	4.2	GO:0000339	RNA cap binding(GO:0000339)
2.1	100.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
2.1	4.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.1	6.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
2.1	6.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
2.1	10.3	GO:0031849	olfactory receptor binding(GO:0031849)
2.0	6.1	GO:0004967	glucagon receptor activity(GO:0004967)
2.0	22.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
2.0	60.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
2.0	16.2	GO:0070700	BMP receptor binding(GO:0070700)
2.0	36.3	GO:0050840	extracellular matrix binding(GO:0050840)
2.0	24.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.0	10.0	GO:0004000	adenosine deaminase activity(GO:0004000)
2.0	21.9	GO:0008408	3'-5' exonuclease activity(GO:0008408)
2.0	6.0	GO:0019976	interleukin-2 binding(GO:0019976)
2.0	6.0	GO:1990226	histone methyltransferase binding(GO:1990226)
2.0	4.0	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
1.9	17.3	GO:0030515	snoRNA binding(GO:0030515)
1.9	3.9	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
1.9	1.9	GO:0015665	alcohol transmembrane transporter activity(GO:0015665)
1.9	5.8	GO:0043422	protein kinase B binding(GO:0043422)
1.9	3.8	GO:0005143	interleukin-12 receptor binding(GO:0005143)
1.9	7.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
1.9	13.3	GO:1990446	U1 snRNP binding(GO:1990446)
1.9	9.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
1.9	13.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.9	255.0	GO:0005125	cytokine activity(GO:0005125)
1.9	16.8	GO:0004623	phospholipase A2 activity(GO:0004623)
1.9	14.9	GO:0042165	neurotransmitter binding(GO:0042165)
1.9	1.9	GO:0010521	telomerase inhibitor activity(GO:0010521)
1.9	316.6	GO:0003735	structural constituent of ribosome(GO:0003735)
1.9	18.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
1.9	40.9	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
1.9	11.1	GO:0043531	ADP binding(GO:0043531)
1.8	16.6	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
1.8	9.2	GO:0016783	sulfurtransferase activity(GO:0016783)
1.8	5.5	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.8	1.8	GO:0004622	lysophospholipase activity(GO:0004622)
1.8	9.1	GO:0015932	nucleobase-containing compound transmembrane transporter activity(GO:0015932)
1.8	9.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.8	1.8	GO:0008061	chitin binding(GO:0008061)
1.8	296.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.8	12.7	GO:0030955	potassium ion binding(GO:0030955)
1.8	421.2	GO:0005198	structural molecule activity(GO:0005198)
1.8	9.0	GO:0005113	patched binding(GO:0005113)
1.8	10.7	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.8	17.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
1.8	5.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
1.8	17.7	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
1.8	3.5	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.8	1.8	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
1.8	8.8	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
1.7	3.5	GO:0015252	hydrogen ion channel activity(GO:0015252)
1.7	13.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.7	19.0	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
1.7	10.3	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
1.7	5.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
1.7	10.2	GO:0016778	diphosphotransferase activity(GO:0016778)
1.7	64.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
1.7	6.7	GO:0017016	Ras GTPase binding(GO:0017016)
1.7	11.7	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
1.7	56.6	GO:0004857	enzyme inhibitor activity(GO:0004857)
1.7	6.6	GO:0004594	pantothenate kinase activity(GO:0004594)
1.7	1.7	GO:0042379	chemokine receptor binding(GO:0042379)
1.6	6.6	GO:0052796	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.6	11.5	GO:0017160	Ral GTPase binding(GO:0017160)
1.6	4.9	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.6	182.1	GO:0003924	GTPase activity(GO:0003924)
1.6	9.7	GO:0008170	N-methyltransferase activity(GO:0008170)
1.6	64.8	GO:0008565	protein transporter activity(GO:0008565)
1.6	824.0	GO:0044822	poly(A) RNA binding(GO:0044822)
1.6	6.4	GO:0039706	co-receptor binding(GO:0039706)
1.6	4.8	GO:0008503	benzodiazepine receptor activity(GO:0008503)
1.6	4.8	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.6	4.8	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
1.6	12.4	GO:0016504	peptidase activator activity(GO:0016504)
1.6	52.8	GO:0019210	kinase inhibitor activity(GO:0019210)
1.5	1.5	GO:0051373	FATZ binding(GO:0051373)
1.5	40.7	GO:0008234	cysteine-type peptidase activity(GO:0008234)
1.5	251.9	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
1.5	3.0	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
1.5	20.6	GO:0005537	mannose binding(GO:0005537)
1.5	2.9	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.5	1.5	GO:0015927	trehalase activity(GO:0015927)
1.4	5.8	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
1.4	8.6	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.4	17.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
1.4	15.7	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
1.4	2.8	GO:0030911	TPR domain binding(GO:0030911)
1.4	9.9	GO:0035586	purinergic receptor activity(GO:0035586)
1.4	7.0	GO:0030742	GTP-dependent protein binding(GO:0030742)
1.4	23.8	GO:0001047	core promoter binding(GO:0001047)
1.4	5.5	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
1.4	1.4	GO:0031750	D3 dopamine receptor binding(GO:0031750)
1.4	10.8	GO:0015377	cation:chloride symporter activity(GO:0015377)
1.4	12.2	GO:0043022	ribosome binding(GO:0043022)
1.4	9.5	GO:0005351	sugar:proton symporter activity(GO:0005351)
1.4	1.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.4	2.7	GO:0035197	siRNA binding(GO:0035197)
1.3	9.4	GO:0003796	lysozyme activity(GO:0003796)
1.3	6.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.3	11.9	GO:0003724	RNA helicase activity(GO:0003724)
1.3	8.0	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.3	1.3	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
1.3	6.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.3	24.6	GO:0051117	ATPase binding(GO:0051117)
1.3	20.7	GO:0005501	retinoid binding(GO:0005501)
1.3	1.3	GO:0070840	dynein complex binding(GO:0070840)
1.3	2.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
1.3	12.6	GO:0005112	Notch binding(GO:0005112)
1.2	22.5	GO:0051087	chaperone binding(GO:0051087)
1.2	6.2	GO:0051400	BH domain binding(GO:0051400)
1.2	19.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.2	1.2	GO:0070052	collagen V binding(GO:0070052)
1.2	2.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.2	49.1	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
1.2	1.2	GO:0019956	chemokine binding(GO:0019956)
1.2	1.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
1.2	3.5	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
1.2	1.2	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
1.2	1.2	GO:0008308	voltage-gated anion channel activity(GO:0008308)
1.2	1.2	GO:0070878	primary miRNA binding(GO:0070878)
1.2	12.8	GO:0008422	beta-glucosidase activity(GO:0008422)
1.1	4.6	GO:0019763	immunoglobulin receptor activity(GO:0019763)
1.1	22.9	GO:0051082	unfolded protein binding(GO:0051082)
1.1	13.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
1.1	5.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
1.1	29.3	GO:0004519	endonuclease activity(GO:0004519)
1.1	4.5	GO:0000989	transcription factor activity, transcription factor binding(GO:0000989)
1.1	6.7	GO:0019865	immunoglobulin binding(GO:0019865)
1.1	27.7	GO:0015464	acetylcholine receptor activity(GO:0015464)
1.1	12.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
1.1	3.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
1.1	16.3	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
1.1	18.3	GO:0061134	peptidase regulator activity(GO:0061134)
1.1	1.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.0	1.0	GO:0019237	centromeric DNA binding(GO:0019237)
1.0	1.0	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
1.0	113.8	GO:0005525	GTP binding(GO:0005525)
1.0	12.3	GO:0030507	spectrin binding(GO:0030507)
1.0	4.9	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
1.0	97.7	GO:0003779	actin binding(GO:0003779)
1.0	7.8	GO:0016790	thiolester hydrolase activity(GO:0016790)
1.0	63.0	GO:0003712	transcription cofactor activity(GO:0003712)
1.0	20.3	GO:0050699	WW domain binding(GO:0050699)
1.0	1.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
1.0	2.9	GO:0017089	glycolipid transporter activity(GO:0017089)
1.0	74.5	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.9	8.4	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9	1.9	GO:0051380	norepinephrine binding(GO:0051380)
0.9	2.8	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.9	45.4	GO:0051015	actin filament binding(GO:0051015)
0.9	10.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.9	27.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.9	1.8	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.9	15.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.9	8.7	GO:0000049	tRNA binding(GO:0000049)
0.8	1.7	GO:0035613	RNA stem-loop binding(GO:0035613)
0.8	9.3	GO:0042805	actinin binding(GO:0042805)
0.8	1.7	GO:0070097	delta-catenin binding(GO:0070097)
0.8	1.7	GO:0015248	sterol transporter activity(GO:0015248)
0.8	4.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.8	0.8	GO:0031893	vasopressin receptor binding(GO:0031893)
0.8	3.3	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.8	7.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.8	2.5	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.8	34.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8	3.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.8	49.1	GO:0019902	phosphatase binding(GO:0019902)
0.8	3.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8	12.4	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.8	6.2	GO:0005222	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.8	0.8	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.8	4.6	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.7	1.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.7	2.2	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7	3.0	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.7	19.9	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.7	2.2	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.7	4.4	GO:0004540	ribonuclease activity(GO:0004540)
0.7	1.5	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.7	574.8	GO:0003677	DNA binding(GO:0003677)
0.7	3.6	GO:0005000	vasopressin receptor activity(GO:0005000)
0.7	3.6	GO:0004994	somatostatin receptor activity(GO:0004994)
0.7	1.4	GO:0019959	interleukin-8 binding(GO:0019959)
0.7	7.7	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.7	12.7	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.7	0.7	GO:0032190	acrosin binding(GO:0032190)
0.6	1.8	GO:0070513	death domain binding(GO:0070513)
0.6	1.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.6	1.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.6	17.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.6	0.6	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.5	5.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.5	2.6	GO:0031386	protein tag(GO:0031386)
0.5	2.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.5	1.4	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.5	3.7	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.5	107.9	GO:0008270	zinc ion binding(GO:0008270)
0.4	16.9	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.4	0.9	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.4	5.7	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.4	0.4	GO:0048019	receptor antagonist activity(GO:0048019)
0.4	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.4	0.8	GO:0031690	adrenergic receptor binding(GO:0031690)
0.4	0.8	GO:0050780	dopamine receptor binding(GO:0050780)
0.4	6.6	GO:0005319	lipid transporter activity(GO:0005319)
0.4	15.2	GO:0008527	taste receptor activity(GO:0008527)
0.4	8.4	GO:0004175	endopeptidase activity(GO:0004175)
0.4	3.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.4	1.1	GO:0042301	phosphate ion binding(GO:0042301)
0.4	6.2	GO:0016503	pheromone receptor activity(GO:0016503)
0.4	0.4	GO:0070697	activin receptor binding(GO:0070697)
0.3	3.1	GO:0051020	GTPase binding(GO:0051020)
0.3	27.9	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(GO:0016818)
0.3	4.9	GO:0001594	trace-amine receptor activity(GO:0001594)
0.3	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.3	6.1	GO:0000287	magnesium ion binding(GO:0000287)
0.3	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	0.9	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.3	1.4	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.3	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.3	0.8	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.3	0.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.2	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.2	1.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	1.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.2	2.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	0.2	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.2	216.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.2	22.6	GO:0003676	nucleic acid binding(GO:0003676)
0.2	17.2	GO:0005550	pheromone binding(GO:0005550)
0.2	16.3	GO:0030246	carbohydrate binding(GO:0030246)
0.2	3.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.1	GO:0015926	glucosidase activity(GO:0015926)
0.1	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.2	GO:0016421	CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
0.1	1.4	GO:0005186	pheromone activity(GO:0005186)
0.1	0.1	GO:0023023	MHC protein complex binding(GO:0023023)
0.1	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.0	2.9	GO:0005179	hormone activity(GO:0005179)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.0	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.0	21.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
11.8	106.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
9.8	244.7	PID IGF1 PATHWAY	IGF1 pathway
9.5	238.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
9.5	133.5	PID IL5 PATHWAY	IL5-mediated signaling events
9.3	353.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
9.3	120.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
9.0	161.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
8.9	499.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
8.7	8.7	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
8.7	130.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
8.6	77.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
8.1	72.7	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
7.9	118.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
7.8	7.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
7.7	92.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
7.6	106.9	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
7.5	15.1	PID IFNG PATHWAY	IFN-gamma pathway
7.4	331.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
7.4	250.2	PID ILK PATHWAY	Integrin-linked kinase signaling
7.3	29.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
7.3	255.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
7.2	101.5	ST P38 MAPK PATHWAY	p38 MAPK Pathway
7.2	86.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
7.2	164.9	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
7.0	14.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
7.0	14.1	PID S1P S1P2 PATHWAY	S1P2 pathway
7.0	139.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
6.9	159.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
6.9	41.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
6.8	101.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
6.7	53.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
6.6	33.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
6.4	70.5	PID EPO PATHWAY	EPO signaling pathway
6.4	293.5	PID P73PATHWAY	p73 transcription factor network
6.2	6.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
6.1	140.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
6.1	18.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
5.9	304.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
5.8	116.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
5.8	145.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
5.7	158.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
5.6	61.8	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
5.4	70.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
5.4	166.7	PID P53 REGULATION PATHWAY	p53 pathway
5.3	73.8	PID RAC1 PATHWAY	RAC1 signaling pathway
5.2	109.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
5.0	75.4	PID AURORA A PATHWAY	Aurora A signaling
5.0	69.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
4.9	24.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
4.7	9.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
4.7	79.1	PID RHOA PATHWAY	RhoA signaling pathway
4.6	18.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
4.6	18.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
4.6	50.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
4.6	18.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
4.5	45.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
4.5	18.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
4.5	117.1	PID AP1 PATHWAY	AP-1 transcription factor network
4.5	58.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
4.4	31.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
4.4	75.6	PID IL1 PATHWAY	IL1-mediated signaling events
4.3	213.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
4.3	8.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
4.2	97.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
4.2	59.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
4.2	50.5	ST GAQ PATHWAY	G alpha q Pathway
4.2	29.4	PID CD40 PATHWAY	CD40/CD40L signaling
4.2	12.6	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
4.1	12.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
4.1	65.6	PID ARF6 PATHWAY	Arf6 signaling events
4.1	4.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
4.1	4.1	PID MYC PATHWAY	C-MYC pathway
4.1	57.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
4.1	109.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
4.0	16.0	PID FOXO PATHWAY	FoxO family signaling
4.0	55.5	PID BCR 5PATHWAY	BCR signaling pathway
3.9	63.1	PID TNF PATHWAY	TNF receptor signaling pathway
3.9	39.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
3.9	96.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
3.7	227.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
3.6	61.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
3.6	90.3	PID MTOR 4PATHWAY	mTOR signaling pathway
3.6	65.0	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
3.6	14.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
3.5	92.1	PID PLK1 PATHWAY	PLK1 signaling events
3.4	10.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
3.3	19.9	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
3.3	19.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
3.3	58.9	PID AURORA B PATHWAY	Aurora B signaling
3.1	112.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
3.1	15.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
3.1	3.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
3.1	55.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
3.0	27.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
3.0	42.0	PID BARD1 PATHWAY	BARD1 signaling events
2.9	14.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
2.9	5.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
2.9	37.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
2.9	20.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
2.8	22.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
2.7	27.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
2.6	13.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
2.6	36.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
2.6	28.4	PID ERBB4 PATHWAY	ErbB4 signaling events
2.6	12.8	PID ATM PATHWAY	ATM pathway
2.5	17.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.5	35.4	PID ATR PATHWAY	ATR signaling pathway
2.5	45.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
2.5	29.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
2.4	21.5	PID ALK1 PATHWAY	ALK1 signaling events
2.3	25.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
2.3	55.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
2.3	20.6	PID ALK2 PATHWAY	ALK2 signaling events
2.3	4.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
2.3	9.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
2.3	435.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.2	2.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
2.2	21.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
2.2	38.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
2.1	2.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
2.1	2.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
2.1	16.7	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
2.0	6.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
2.0	31.8	PID IL12 2PATHWAY	IL12-mediated signaling events
2.0	13.9	PID RAS PATHWAY	Regulation of Ras family activation
1.9	32.8	PID LKB1 PATHWAY	LKB1 signaling events
1.9	19.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
1.9	34.5	PID IL23 PATHWAY	IL23-mediated signaling events
1.9	15.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
1.9	5.7	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
1.9	39.6	PID CONE PATHWAY	Visual signal transduction: Cones
1.8	3.6	SIG CHEMOTAXIS	Genes related to chemotaxis
1.8	19.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
1.7	3.4	PID TRAIL PATHWAY	TRAIL signaling pathway
1.7	54.1	PID CMYB PATHWAY	C-MYB transcription factor network
1.7	5.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
1.7	11.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.6	3.2	PID S1P S1P4 PATHWAY	S1P4 pathway
1.5	15.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
1.5	6.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
1.5	29.8	PID E2F PATHWAY	E2F transcription factor network
1.5	3.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
1.5	41.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
1.5	10.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.4	10.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
1.4	22.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.3	14.0	PID ARF 3PATHWAY	Arf1 pathway
1.3	6.3	ST G ALPHA S PATHWAY	G alpha s Pathway
1.3	15.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.2	166.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.2	4.8	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
1.2	3.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.2	4.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
1.2	21.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.2	9.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.1	3.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.1	9.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
1.1	29.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.1	1.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.1	3.3	ST GA12 PATHWAY	G alpha 12 Pathway
1.1	2.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.1	141.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.1	8.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.0	6.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
1.0	30.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.0	11.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.8	4.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.7	5.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.7	33.5	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.7	10.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.5	0.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.5	2.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.5	6.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.4	0.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.4	2.6	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.4	2.9	PID ENDOTHELIN PATHWAY	Endothelins
0.4	1.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.3	3.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.2	45.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.2	1.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	1.7	PID FGF PATHWAY	FGF signaling pathway
0.1	1.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	1.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.5	216.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
12.7	114.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
11.6	93.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
11.0	121.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
10.7	53.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
10.1	101.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
10.1	171.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
9.9	99.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
9.4	112.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
9.2	18.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
9.2	128.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
9.0	99.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
8.9	98.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
8.9	53.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
8.8	114.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
8.7	78.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
8.7	227.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
8.7	87.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
8.6	25.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
8.4	58.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
8.3	141.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
8.2	123.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
8.1	154.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
8.1	8.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
8.1	209.7	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
8.0	40.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
8.0	112.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
8.0	8.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
7.9	47.6	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
7.9	39.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
7.9	142.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
7.9	31.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
7.8	101.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
7.5	74.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
7.4	178.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
7.2	166.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
7.1	71.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
7.1	170.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
7.0	98.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
7.0	209.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
6.9	27.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
6.9	75.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
6.8	182.8	REACTOME G1 PHASE	Genes involved in G1 Phase
6.7	13.4	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
6.7	53.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
6.6	59.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
6.5	91.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
6.5	78.2	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
6.4	45.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
6.4	6.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
6.4	120.9	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
6.4	38.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
6.3	63.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
6.3	63.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
6.3	68.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
6.2	56.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
6.2	93.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
6.1	61.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
6.1	559.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
6.1	152.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
6.1	91.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
6.1	230.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
6.0	42.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
6.0	137.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
5.9	5.9	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
5.9	11.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
5.7	51.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
5.7	45.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
5.4	54.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
5.4	10.8	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
5.4	96.7	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
5.4	80.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
5.3	10.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
5.3	143.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
5.2	57.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
5.2	129.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
5.1	20.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
5.1	50.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
5.0	70.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
5.0	35.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
5.0	267.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
4.8	53.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
4.8	106.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
4.8	52.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
4.7	4.7	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
4.7	71.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
4.7	61.1	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
4.6	18.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
4.6	36.6	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
4.6	255.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
4.6	41.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
4.5	9.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
4.4	115.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
4.3	112.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
4.3	34.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
4.3	38.8	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
4.3	47.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
4.3	132.1	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
4.2	25.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
4.2	83.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
4.1	12.4	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
4.1	28.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
4.1	65.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
4.1	44.7	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
4.1	133.9	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
4.0	28.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
4.0	75.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
4.0	99.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
4.0	99.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
4.0	15.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
4.0	47.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
4.0	87.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
4.0	19.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
3.9	165.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
3.9	74.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
3.9	11.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
3.9	155.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
3.9	11.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
3.8	11.5	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
3.8	22.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
3.8	19.0	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
3.8	15.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
3.7	66.9	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
3.7	29.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
3.7	29.5	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
3.7	132.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
3.7	18.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
3.6	76.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
3.6	98.0	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
3.6	28.9	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
3.6	10.8	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
3.6	157.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
3.6	50.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
3.5	28.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
3.5	53.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
3.5	155.4	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
3.5	94.7	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
3.5	28.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
3.5	34.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
3.5	31.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
3.4	13.7	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
3.4	13.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
3.3	33.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
3.3	66.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
3.3	180.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
3.3	72.0	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
3.2	38.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
3.2	9.7	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
3.2	57.4	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
3.2	12.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
3.2	9.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
3.1	6.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
3.0	24.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
3.0	29.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
3.0	23.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
2.9	22.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
2.9	323.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
2.9	79.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
2.8	56.4	REACTOME DNA REPLICATION	Genes involved in DNA Replication
2.8	146.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
2.8	14.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
2.8	27.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
2.8	63.7	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
2.8	74.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
2.8	77.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
2.7	60.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
2.7	305.7	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
2.7	13.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
2.6	5.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.6	7.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
2.6	7.8	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
2.6	20.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
2.6	38.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
2.6	12.9	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
2.6	10.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
2.6	20.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
2.5	2.5	REACTOME S PHASE	Genes involved in S Phase
2.5	221.5	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
2.5	17.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
2.5	19.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
2.4	4.9	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
2.4	7.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
2.3	30.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
2.3	15.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
2.2	62.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
2.2	17.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
2.2	4.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
2.2	39.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
2.2	19.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
2.2	47.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
2.1	61.1	REACTOME TRANSLATION	Genes involved in Translation
2.1	22.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
2.1	30.9	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
2.1	180.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
2.1	4.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
2.0	18.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
2.0	22.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.0	46.0	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
2.0	10.0	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
2.0	4.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
2.0	82.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.9	11.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
1.9	1.9	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.9	11.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
1.8	1.8	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
1.8	42.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
1.8	76.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.8	8.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
1.7	32.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
1.7	8.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.7	45.3	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
1.7	1.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.6	4.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.6	19.3	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
1.6	4.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
1.6	1.6	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
1.5	23.2	REACTOME MEIOSIS	Genes involved in Meiosis
1.4	43.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
1.4	11.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.4	16.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.3	11.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3	2.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.1	24.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.1	6.4	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.1	75.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1.0	3.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
1.0	4.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
1.0	1.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
1.0	1.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
1.0	2.9	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
1.0	11.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
1.0	16.5	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.9	15.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.9	23.5	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.9	4.5	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.8	46.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.8	10.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.7	11.0	REACTOME APOPTOSIS	Genes involved in Apoptosis
0.7	2.7	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.7	3.4	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.6	7.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6	4.5	REACTOME OPSINS	Genes involved in Opsins
0.4	10.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	51.4	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2	9.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	2.6	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
0.2	2.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	2.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	0.3	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.1	0.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	3.4	REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	Genes involved in Post-translational protein modification
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.4	REACTOME DEFENSINS	Genes involved in Defensins
0.1	1.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation