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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Hlx

Z-value: 0.82

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Transcription factors associated with Hlx

Gene Symbol	Gene ID	Gene Info
Hlx Ensembl NCBI MGI UniProt	ENSMUSG00000039377.6	Hlx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Hlx	chr1_184727788_184727992	3708	0.171022	-0.24	7.7e-02	Click!
Hlx	chr1_184731813_184732486	470	0.749555	-0.15	2.9e-01	Click!
Hlx	chr1_184727523_184727685	3994	0.166076	-0.14	3.0e-01	Click!
Hlx	chr1_184732596_184733212	285	0.870881	0.09	5.0e-01	Click!
Hlx	chr1_184733319_184733470	775	0.552845	-0.03	8.5e-01	Click!

Activity of the Hlx motif across conditions

Conditions sorted by the z-value of the Hlx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_117897075_117897226	3.87	4933411E08Rik	RIKEN cDNA 4933411E08 gene	28309	0.12
chr2_119566179_119566455	3.76	Chp1	calcineurin-like EF hand protein 1	288	0.85
chr1_177475904_177476057	3.63	Gm37306	predicted gene, 37306	8602	0.17
chrX_93831605_93832731	3.58	Pdk3	pyruvate dehydrogenase kinase, isoenzyme 3	33	0.98
chr19_43767999_43768210	3.53	Cutc	cutC copper transporter	3231	0.18
chr4_117136303_117136464	3.49	Plk3	polo like kinase 3	2420	0.1
chr16_78040391_78040542	2.74	Gm25025	predicted gene, 25025	10251	0.23
chr10_69253249_69253618	2.40	Rhobtb1	Rho-related BTB domain containing 1	12204	0.19
chr13_62952253_62952404	2.40	Gm48812	predicted gene, 48812	2886	0.22
chr4_49451596_49451772	2.39	Acnat1	acyl-coenzyme A amino acid N-acyltransferase 1	547	0.69
chr13_47111196_47111529	2.37	1700026N04Rik	RIKEN cDNA 1700026N04 gene	4943	0.13
chr13_93234781_93234932	2.25	Tent2	terminal nucleotidyltransferase 2	42471	0.12
chr4_14273616_14273932	2.15	Gm24908	predicted gene, 24908	34156	0.18
chr3_108771125_108771338	2.14	Aknad1	AKNA domain containing 1	11017	0.15
chr11_4095576_4095728	2.11	Mtfp1	mitochondrial fission process 1	207	0.87
chr3_34504199_34504577	2.10	Gm29135	predicted gene 29135	22181	0.16
chr15_98608664_98610204	2.09	Adcy6	adenylate cyclase 6	598	0.55
chr7_45103031_45103408	2.04	Fcgrt	Fc receptor, IgG, alpha chain transporter	133	0.83
chr10_125785483_125786054	2.02	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	180400	0.03
chr5_136739184_136739335	1.86	Col26a1	collagen, type XXVI, alpha 1	5290	0.23
chrX_10877865_10878215	1.71	Gm14473	predicted gene 14473	12407	0.26
chr13_36202916_36203067	1.63	Gm48765	predicted gene, 48765	13268	0.16
chr1_59212186_59212347	1.59	Als2	alsin Rho guanine nucleotide exchange factor	6860	0.17
chr10_120387024_120387466	1.57	9230105E05Rik	RIKEN cDNA 9230105E05 gene	2278	0.28
chr16_44672098_44672717	1.57	Nepro	nucleolus and neural progenitor protein	51894	0.11
chr8_125782363_125782518	1.54	Pcnx2	pecanex homolog 2	8312	0.24
chr13_101427845_101427996	1.52	Gm36994	predicted gene, 36994	15331	0.2
chr1_162020499_162020732	1.49	2810442N19Rik	RIKEN cDNA 2810442N19 gene	15443	0.14
chr7_75761095_75761254	1.43	Gm23251	predicted gene, 23251	3806	0.19
chr9_113833592_113833892	1.42	Clasp2	CLIP associating protein 2	21142	0.2
chr4_132072343_132072494	1.39	Epb41	erythrocyte membrane protein band 4.1	321	0.8
chr11_78401648_78401948	1.39	Slc13a2os	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, opposite strand	7313	0.1
chr2_170091681_170092036	1.37	Zfp217	zinc finger protein 217	39362	0.2
chr13_63039019_63039172	1.36	Aopep	aminopeptidase O	23602	0.15
chr4_154359614_154359823	1.33	Prdm16	PR domain containing 16	11261	0.18
chr1_36670453_36670635	1.32	Gm24133	predicted gene, 24133	6579	0.12
chr14_7896790_7896982	1.30	Flnb	filamin, beta	12145	0.19
chr17_56036249_56036917	1.26	Sh3gl1	SH3-domain GRB2-like 1	7	0.94
chr14_21462396_21462784	1.25	Gm30363	predicted gene, 30363	8831	0.19
chr2_60142673_60142824	1.25	Ldha-ps	lactate dehydrogenase A, pseudogene	8693	0.16
chr19_24534375_24534662	1.22	Pip5k1b	phosphatidylinositol-4-phosphate 5-kinase, type 1 beta	21271	0.17
chr14_122909784_122909949	1.22	4930594M22Rik	RIKEN cDNA 4930594M22 gene	3164	0.2
chr9_32545148_32545570	1.21	Fli1	Friend leukemia integration 1	2498	0.19
chr13_14040175_14040467	1.21	Tbce	tubulin-specific chaperone E	683	0.47
chr6_71130459_71130610	1.20	Thnsl2	threonine synthase-like 2 (bacterial)	1438	0.31
chr8_110022869_110023026	1.20	Gm45888	predicted gene 45888	8623	0.12
chr7_75863314_75863477	1.20	Klhl25	kelch-like 25	14954	0.22
chr10_53101557_53101708	1.19	Gm47622	predicted gene, 47622	911	0.65
chr2_85172390_85172701	1.17	Gm13713	predicted gene 13713	11767	0.11
chr13_43480925_43481874	1.17	Ranbp9	RAN binding protein 9	117	0.95
chr11_3170338_3170795	1.13	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	138	0.93
chr4_97601207_97601387	1.13	E130114P18Rik	RIKEN cDNA E130114P18 gene	16661	0.23
chr14_19707913_19708072	1.13	Gm49341	predicted gene, 49341	10783	0.13
chr5_21264473_21264673	1.10	Gsap	gamma-secretase activating protein	13414	0.16
chr18_56871340_56871513	1.10	Gm18087	predicted gene, 18087	44662	0.14
chr4_137481273_137481486	1.09	Hspg2	perlecan (heparan sulfate proteoglycan 2)	12576	0.13
chr10_71338295_71338446	1.08	Cisd1	CDGSH iron sulfur domain 1	6584	0.14
chr13_62888714_62888865	1.06	Fbp1	fructose bisphosphatase 1	507	0.73
chr5_103753230_103754272	1.06	Aff1	AF4/FMR2 family, member 1	411	0.87
chr12_47466088_47466239	1.05	Gm48578	predicted gene, 48578	66094	0.15
chr15_102753205_102753442	1.02	Calcoco1	calcium binding and coiled coil domain 1	31145	0.11
chr2_167713774_167713925	1.02	A530013C23Rik	RIKEN cDNA A530013C23 gene	22668	0.1
chr16_45924188_45924367	1.01	Gm15640	predicted gene 15640	12046	0.17
chr15_7625219_7625370	1.01	Gm37743	predicted gene, 37743	45046	0.15
chr11_69418367_69419708	0.99	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	5362	0.09
chr1_84993310_84993634	0.99	Gm29284	predicted gene 29284	440	0.72
chr2_151976038_151976372	0.98	Fam110a	family with sequence similarity 110, member A	2239	0.21
chr6_143142224_143142402	0.98	Gm44306	predicted gene, 44306	7226	0.14
chr2_155894841_155894992	0.98	Uqcc1	ubiquinol-cytochrome c reductase complex assembly factor 1	15688	0.12
chr8_94898997_94899206	0.97	Ccdc102a	coiled-coil domain containing 102A	18420	0.1
chr4_137858517_137858672	0.96	Ece1	endothelin converting enzyme 1	3643	0.24
chr16_25293836_25294037	0.96	Tprg	transformation related protein 63 regulated	7115	0.32
chr6_140147796_140147947	0.95	Gm44159	predicted gene, 44159	15804	0.17
chr15_75863041_75863192	0.93	Gsdmd	gasdermin D	737	0.46
chr2_109995179_109995348	0.92	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	5265	0.22
chr4_142049656_142049814	0.91	Gm13053	predicted gene 13053	1157	0.39
chr1_85615441_85615607	0.90	Gm10552	predicted gene 10552	3628	0.12
chr6_25664249_25664412	0.90	Gpr37	G protein-coupled receptor 37	25462	0.25
chr1_66922212_66922363	0.90	Myl1	myosin, light polypeptide 1	12411	0.12
chr2_171734745_171734896	0.86	1700028P15Rik	RIKEN cDNA 1700028P15 gene	227311	0.02
chr1_88491666_88491830	0.86	Glrp1	glutamine repeat protein 1	18318	0.14
chr9_63201505_63201702	0.84	Skor1	SKI family transcriptional corepressor 1	52642	0.12
chr2_18586936_18587492	0.84	Gm13353	predicted gene 13353	19088	0.18
chr14_16962435_16962707	0.82	Gm18078	predicted gene, 18078	8965	0.24
chr11_62605415_62606716	0.82	Lrrc75aos2	leucine rich repeat containing 75A, opposite strand 2	298	0.72
chr1_80408527_80409167	0.82	Gm6189	predicted gene 6189	23662	0.13
chr7_100559420_100559571	0.81	Mrpl48	mitochondrial ribosomal protein L48	11875	0.09
chr1_45767537_45767744	0.81	Gm8307	predicted gene 8307	697	0.6
chr7_6781231_6781382	0.81	Mir3099	microRNA 3099	22281	0.09
chr7_137306238_137306389	0.80	Ebf3	early B cell factor 3	7603	0.2
chr17_25127767_25127933	0.79	Clcn7	chloride channel, voltage-sensitive 7	5541	0.1
chr9_50501327_50501514	0.79	Plet1os	placenta expressed transcript 1, opposite strand	3385	0.16
chr1_176995106_176995337	0.78	Sdccag8	serologically defined colon cancer antigen 8	2788	0.21
chr1_85032083_85032289	0.77	AC167036.2	novel protein	3342	0.13
chr5_151046930_151047128	0.77	Gm8675	predicted gene 8675	37728	0.16
chrX_38473528_38474265	0.77	Gm7598	predicted gene 7598	2565	0.27
chr14_17786377_17786528	0.77	Gm48320	predicted gene, 48320	15330	0.28
chr2_172261099_172261318	0.75	Mc3r	melanocortin 3 receptor	12716	0.17
chr3_28060860_28061033	0.75	Pld1	phospholipase D1	8568	0.28
chr2_170158021_170158172	0.74	Zfp217	zinc finger protein 217	9993	0.28
chr1_98147453_98147604	0.74	1810006J02Rik	RIKEN cDNA 1810006J02 gene	16061	0.18
chr7_101837492_101838185	0.73	Inppl1	inositol polyphosphate phosphatase-like 1	35	0.49
chr1_130732805_130732969	0.73	AA986860	expressed sequence AA986860	777	0.43
chr10_128336232_128336487	0.72	Cs	citrate synthase	1375	0.18
chr10_20046153_20046446	0.72	Map3k5	mitogen-activated protein kinase kinase kinase 5	53226	0.13
chr3_115660838_115661123	0.72	S1pr1	sphingosine-1-phosphate receptor 1	54092	0.13
chr4_106909039_106909761	0.71	Ssbp3	single-stranded DNA binding protein 3	1301	0.48
chr14_117674551_117674852	0.70	Mir6239	microRNA 6239	279146	0.01
chr1_166002288_166003185	0.69	Pou2f1	POU domain, class 2, transcription factor 1	58	0.72
chr12_75826912_75827184	0.69	Syne2	spectrin repeat containing, nuclear envelope 2	8698	0.25
chr11_4553637_4553951	0.68	Mtmr3	myotubularin related protein 3	7526	0.17
chr1_192823078_192823550	0.66	Gm38360	predicted gene, 38360	2187	0.22
chr12_103969871_103970197	0.65	Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	11059	0.1
chr6_134147989_134148473	0.64	Gm17088	predicted gene 17088	23776	0.18
chr7_65803210_65803361	0.64	1810008I18Rik	RIKEN cDNA 1810008I18 gene	174	0.95
chr1_64087943_64089121	0.63	Gm13748	predicted gene 13748	9878	0.19
chr17_47914586_47915244	0.63	Gm15556	predicted gene 15556	7463	0.14
chr10_18370345_18371012	0.63	Nhsl1	NHS-like 1	19644	0.19
chr3_60500259_60500437	0.62	Mbnl1	muscleblind like splicing factor 1	587	0.8
chr2_93008105_93008300	0.62	Prdm11	PR domain containing 11	5708	0.22
chr11_105549454_105549608	0.62	Tanc2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	40455	0.15
chr7_19119292_19119545	0.61	Fbxo46	F-box protein 46	441	0.56
chr13_22020931_22021318	0.61	Gm11290	predicted gene 11290	3618	0.06
chr12_109552974_109553125	0.61	Meg3	maternally expressed 3	3794	0.05
chr6_89291609_89291772	0.61	4930512J16Rik	RIKEN cDNA 4930512J16 gene	5965	0.14
chr2_34825635_34825786	0.60	Fbxw2	F-box and WD-40 domain protein 2	312	0.82
chr17_78327187_78327654	0.60	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	23469	0.16
chr19_9924707_9924858	0.59	Gm36913	predicted gene, 36913	3752	0.1
chr17_78273911_78274066	0.59	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	6195	0.2
chr12_52671451_52671886	0.58	Akap6	A kinase (PRKA) anchor protein 6	27715	0.15
chr12_37142164_37142324	0.58	Meox2	mesenchyme homeobox 2	33704	0.16
chr8_104365772_104365923	0.58	Gm45877	predicted gene 45877	2179	0.16
chr2_178610675_178610841	0.57	Cdh26	cadherin-like 26	150128	0.04
chr11_53818750_53818901	0.57	Gm12216	predicted gene 12216	22950	0.11
chr18_23748563_23748754	0.57	Gm15972	predicted gene 15972	3647	0.2
chr3_95517252_95517598	0.56	Ctss	cathepsin S	9361	0.1
chr11_98925326_98925710	0.56	Rara	retinoic acid receptor, alpha	2300	0.17
chr12_54985296_54986516	0.56	Baz1a	bromodomain adjacent to zinc finger domain 1A	30	0.91
chr18_5002577_5002904	0.55	Svil	supervillin	7804	0.3
chr3_129296851_129297002	0.55	Gm42628	predicted gene 42628	11657	0.16
chr14_65737090_65737241	0.55	Scara5	scavenger receptor class A, member 5	60688	0.1
chr11_29547325_29547986	0.54	Rps27a	ribosomal protein S27A	205	0.59
chr4_132874359_132874577	0.54	Stx12	syntaxin 12	10041	0.12
chr17_30611617_30611888	0.54	Glo1	glyoxalase 1	817	0.45
chr18_78350420_78350571	0.54	Gm6133	predicted gene 6133	741	0.78
chr12_112333322_112333806	0.53	Gm38123	predicted gene, 38123	16503	0.18
chr13_95777279_95777613	0.53	Iqgap2	IQ motif containing GTPase activating protein 2	13049	0.19
chr12_105757874_105758401	0.53	Ak7	adenylate kinase 7	12862	0.17
chrX_96134190_96134604	0.53	Gm24718	predicted gene, 24718	16575	0.18
chr1_180179935_180180086	0.53	Coq8a	coenzyme Q8A	1088	0.44
chr10_115263315_115263511	0.53	Gm8942	predicted gene 8942	6565	0.17
chr1_136911165_136911329	0.53	Nr5a2	nuclear receptor subfamily 5, group A, member 2	29336	0.18
chr4_43598778_43598951	0.52	Gm12472	predicted gene 12472	10792	0.07
chr13_37859595_37859751	0.52	Rreb1	ras responsive element binding protein 1	1739	0.39
chr2_174291748_174291899	0.52	Gnasas1	GNAS antisense RNA 1	3566	0.16
chr11_47188652_47188809	0.52	Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	190792	0.03
chr17_86301671_86301829	0.51	2010106C02Rik	RIKEN cDNA 2010106C02 gene	14572	0.27
chr12_79532095_79532284	0.51	Rad51b	RAD51 paralog B	204836	0.02
chr2_167902375_167902526	0.51	Ptpn1	protein tyrosine phosphatase, non-receptor type 1	29607	0.14
chr10_127355403_127355866	0.50	Inhbe	inhibin beta-E	1223	0.25
chr18_74854672_74855018	0.50	Gm24559	predicted gene, 24559	51589	0.08
chr16_95924762_95924926	0.50	1600002D24Rik	RIKEN cDNA 1600002D24 gene	4233	0.21
chr13_42342256_42342434	0.50	Gm47118	predicted gene, 47118	37354	0.17
chr12_117250438_117250838	0.49	Mir153	microRNA 153	179	0.97
chr2_131254315_131254509	0.49	Pank2	pantothenate kinase 2	8083	0.11
chr6_144902234_144902547	0.49	Gm22792	predicted gene, 22792	98758	0.06
chr5_25064693_25064847	0.49	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	35872	0.13
chr1_151580285_151580566	0.48	Fam129a	family with sequence similarity 129, member A	8929	0.17
chr17_56688104_56688477	0.48	Ranbp3	RAN binding protein 3	8445	0.11
chr2_134350455_134350845	0.48	Hao1	hydroxyacid oxidase 1, liver	203657	0.03
chr15_64026966_64027117	0.48	Gm25628	predicted gene, 25628	1093	0.51
chr5_15487606_15487855	0.48	Gm21149	predicted gene, 21149	11207	0.16
chr7_35116059_35116210	0.48	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	3159	0.12
chr3_55075221_55075624	0.48	Gm43555	predicted gene 43555	17766	0.13
chr11_22348041_22348563	0.47	Ehbp1	EH domain binding protein 1	6010	0.25
chr9_104071426_104071577	0.47	Acad11	acyl-Coenzyme A dehydrogenase family, member 11	7768	0.1
chr9_69291313_69291464	0.47	Rora	RAR-related orphan receptor alpha	1706	0.45
chr1_17655681_17656007	0.47	Gm28154	predicted gene 28154	14763	0.2
chr17_84777000_84777216	0.46	Lrpprc	leucine-rich PPR-motif containing	435	0.81
chr11_105125823_105126961	0.46	Mettl2	methyltransferase like 2	33	0.97
chr8_109567958_109568109	0.46	Txnl4b	thioredoxin-like 4B	855	0.48
chr9_79869537_79869690	0.46	Gm20477	predicted gene 20477	31226	0.13
chr16_36707794_36708006	0.46	Ildr1	immunoglobulin-like domain containing receptor 1	7638	0.14
chr8_64746788_64747015	0.45	Klhl2	kelch-like 2, Mayven	8070	0.16
chr8_25772876_25773027	0.45	Bag4	BCL2-associated athanogene 4	4631	0.11
chr10_102895997_102896156	0.45	Gm5175	predicted gene 5175	76705	0.1
chr4_141734704_141734869	0.45	Ddi2	DNA-damage inducible protein 2	11367	0.12
chr19_14596815_14596966	0.44	Tle4	transducin-like enhancer of split 4	1161	0.62
chr1_54913082_54913233	0.44	A130048G24Rik	RIKEN cDNA A130048G24 gene	3437	0.24
chr14_41115323_41115474	0.44	Mat1a	methionine adenosyltransferase I, alpha	10017	0.12
chr15_58796543_58796694	0.44	Gm20712	predicted gene 20712	14667	0.14
chr4_74401736_74401893	0.43	Kdm4c	lysine (K)-specific demethylase 4C	139004	0.04
chr16_52446109_52446270	0.43	Alcam	activated leukocyte cell adhesion molecule	6276	0.33
chr13_80623585_80623746	0.43	Gm46388	predicted gene, 46388	130656	0.05
chr9_122074963_122075114	0.43	Gm39465	predicted gene, 39465	23575	0.1
chr19_55110604_55110837	0.42	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	7629	0.21
chr4_146482529_146482708	0.41	Gm13245	predicted gene 13245	1951	0.25
chr1_136228974_136229345	0.41	Inava	innate immunity activator	860	0.42
chr2_167799405_167799696	0.40	9230111E07Rik	RIKEN cDNA 9230111E07 gene	17497	0.14
chr9_115243693_115243977	0.40	Stmn1-rs1	stathmin 1, related sequence 1	38146	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.5	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.8	3.2	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2	1.0	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.2	0.6	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.2	1.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	0.2	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.4	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.4	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.5	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	2.1	GO:0000266	mitochondrial fission(GO:0000266)
0.1	0.4	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.4	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.2	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1	0.2	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1	0.3	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1	0.3	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.2	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.2	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.4	GO:0070269	pyroptosis(GO:0070269)
0.0	0.3	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.2	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.6	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.2	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	1.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.4	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.5	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.1	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	1.9	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.1	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.2	GO:0022615	protein to membrane docking(GO:0022615)
0.0	0.2	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.1	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.2	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.2	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.3	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.2	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	1.2	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.3	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.0	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.1	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.3	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.1	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0042891	antibiotic transport(GO:0042891)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.0	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.0	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	1.6	GO:0019882	antigen processing and presentation(GO:0019882)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.3	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.2	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.0	GO:0048208	trophectodermal cellular morphogenesis(GO:0001831) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.0	GO:0043366	beta selection(GO:0043366)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0071651	regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.0	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.0	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.0	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0061325	cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0	0.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.0	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.0	GO:0015677	copper ion import(GO:0015677) ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.0	GO:0006680	glucosylceramide catabolic process(GO:0006680)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.3	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0032346	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	1.2	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.2	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.1	0.5	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.2	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.3	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	1.0	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.4	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:1990923	PET complex(GO:1990923)
0.0	0.3	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.4	GO:1990752	microtubule end(GO:1990752)
0.0	0.0	GO:0044326	dendritic spine neck(GO:0044326)
0.0	1.3	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	3.5	GO:0000139	Golgi membrane(GO:0000139)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	1.9	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.6	GO:0005795	Golgi stack(GO:0005795)
0.0	0.1	GO:0070187	telosome(GO:0070187)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.5	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6	1.7	GO:0019770	IgG receptor activity(GO:0019770)
0.2	1.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2	0.5	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.4	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1	0.4	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	1.1	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.1	1.1	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	1.8	GO:0018031	dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.1	0.2	GO:0005119	smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	0.3	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	3.1	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	1.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.3	GO:0008758	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.3	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	2.4	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.0	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.0	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:1990188	euchromatin binding(GO:1990188)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	1.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.3	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling