Project
ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Insm1

Z-value: 0.81

Motif logo

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Transcription factors associated with Insm1

Gene Symbol Gene ID Gene Info
ENSMUSG00000068154.4 Insm1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Insm1chr2_146223031_14622343113100.4262880.501.2e-04Click!
Insm1chr2_146222366_1462226936080.7209590.482.2e-04Click!
Insm1chr2_146221292_1462218643430.8727280.472.5e-04Click!
Insm1chr2_146221890_1462222791630.9504960.431.2e-03Click!
Insm1chr2_146220859_1462211779030.5688060.393.5e-03Click!

Activity of the Insm1 motif across conditions

Conditions sorted by the z-value of the Insm1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_86492150_86492313 2.38 Syn3
synapsin III
334
0.82
chr2_17730264_17731671 2.21 Nebl
nebulette
76
0.98
chr16_49408354_49408582 2.03 Gm4802
predicted gene 4802
4162
0.24
chr5_30718313_30718464 1.86 Dpysl5
dihydropyrimidinase-like 5
6487
0.15
chr8_81341841_81342969 1.63 Inpp4b
inositol polyphosphate-4-phosphatase, type II
151
0.97
chr3_31212846_31213313 1.59 Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
45315
0.14
chr9_114026283_114026988 1.54 Fbxl2
F-box and leucine-rich repeat protein 2
91
0.97
chr1_81593373_81593581 1.47 Gm6198
predicted gene 6198
35994
0.2
chr9_91378183_91378872 1.44 Zic4
zinc finger protein of the cerebellum 4
115
0.94
chr9_106148558_106149196 1.40 D030055H07Rik
RIKEN cDNA D030055H07 gene
190
0.87
chr5_114270076_114270227 1.38 Foxn4
forkhead box N4
3551
0.18
chr8_27009040_27009239 1.34 Gm32389
predicted gene, 32389
672
0.51
chr1_44584898_44585072 1.28 Gm37626
predicted gene, 37626
24100
0.18
chr6_91409483_91409682 1.27 Wnt7a
wingless-type MMTV integration site family, member 7A
1781
0.2
chr13_68608086_68608307 1.26 1700001L19Rik
RIKEN cDNA 1700001L19 gene
10757
0.16
chr1_59520334_59520490 1.19 Gm973
predicted gene 973
3882
0.16
chr14_67383769_67383938 1.18 4930438E09Rik
RIKEN cDNA 4930438E09 gene
13889
0.18
chrX_12839424_12839748 1.17 Gm25063
predicted gene, 25063
30776
0.16
chr9_124441790_124442379 1.13 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
662
0.65
chr1_18058368_18058994 1.10 Gm28756
predicted gene 28756
109
0.82
chr14_25401486_25402359 1.10 Gm26660
predicted gene, 26660
22313
0.15
chr10_22659128_22659399 1.10 Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
10255
0.19
chr14_63605938_63606158 1.09 Xkr6
X-linked Kx blood group related 6
455
0.74
chr6_124915577_124916697 1.07 Ptms
parathymosin
608
0.37
chr1_169917270_169917421 1.07 Ccdc190
coiled-coil domain containing 190
11303
0.16
chr18_25678986_25679896 1.07 0710001A04Rik
RIKEN cDNA 0710001A04 gene
34329
0.19
chr14_57407503_57407692 1.06 Cryl1
crystallin, lambda 1
9068
0.14
chr17_43158272_43158631 1.05 E130008D07Rik
RIKEN cDNA E130008D07 gene
160
0.97
chr2_24428384_24428703 1.05 Pax8
paired box 8
5461
0.15
chr14_14345884_14346978 1.05 Il3ra
interleukin 3 receptor, alpha chain
1
0.93
chr4_124881310_124881874 1.04 Epha10
Eph receptor A10
693
0.52
chr5_106577659_106577832 1.04 Gm29464
predicted gene 29464
2870
0.18
chr17_45548642_45549512 1.04 Tmem151b
transmembrane protein 151B
600
0.55
chr15_54745374_54746077 1.02 Ccn3
cellular communication network factor 3
23
0.98
chr13_63554685_63554897 0.99 Ptch1
patched 1
9024
0.14
chr9_96837880_96838077 0.99 Pxylp1
2-phosphoxylose phosphatase 1
16946
0.13
chr3_118500359_118500534 0.99 Gm37773
predicted gene, 37773
25705
0.13
chr14_76254562_76255004 0.98 2900040C04Rik
RIKEN cDNA 2900040C04 gene
3326
0.28
chr7_64522170_64522321 0.98 Gm45082
predicted gene 45082
6934
0.18
chr7_107594304_107595463 0.97 Ppfibp2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
324
0.83
chr19_53852370_53852680 0.97 Rbm20
RNA binding motif protein 20
9315
0.15
chr7_4690491_4690723 0.97 Brsk1
BR serine/threonine kinase 1
3
0.94
chr16_37685228_37685599 0.96 Gm4600
predicted gene 4600
11927
0.18
chr19_59196387_59196556 0.95 Gm50429
predicted gene, 50429
15816
0.14
chr8_123892085_123892528 0.94 Acta1
actin, alpha 1, skeletal muscle
2445
0.15
chr14_66494473_66494955 0.94 Gm23899
predicted gene, 23899
96981
0.07
chr2_33628909_33629095 0.93 Lmx1b
LIM homeobox transcription factor 1 beta
3281
0.2
chr1_79697057_79697222 0.92 Ap1s3
adaptor-related protein complex AP-1, sigma 3
25167
0.16
chr5_9724986_9725244 0.91 Grm3
glutamate receptor, metabotropic 3
55
0.98
chr6_112516670_112516821 0.91 Gm27944
predicted gene, 27944
3298
0.22
chr11_32063745_32064107 0.90 Gm12108
predicted gene 12108
37302
0.15
chr1_156303318_156303677 0.89 4930518J20Rik
RIKEN cDNA 4930518J20 gene
8
0.59
chr9_21204509_21205302 0.88 Pde4a
phosphodiesterase 4A, cAMP specific
8200
0.1
chr11_61485173_61485597 0.87 Mfap4
microfibrillar-associated protein 4
46
0.96
chr9_46350452_46350942 0.87 Gm31374
predicted gene, 31374
7922
0.12
chr12_56301797_56302273 0.87 Mbip
MAP3K12 binding inhibitory protein 1
43786
0.11
chr13_93855099_93855270 0.87 Mir5624
microRNA 5624
64407
0.08
chr3_83127910_83128196 0.86 Dchs2
dachsous cadherin related 2
105
0.95
chr9_87015281_87015918 0.86 Ripply2
ripply transcriptional repressor 2
37
0.97
chr4_22480159_22480349 0.86 Pou3f2
POU domain, class 3, transcription factor 2
8112
0.17
chr6_83794439_83795940 0.86 Nagk
N-acetylglucosamine kinase
19
0.94
chr4_152273539_152274471 0.85 Gpr153
G protein-coupled receptor 153
227
0.89
chr6_53819165_53819382 0.85 Gm16499
predicted gene 16499
530
0.71
chrX_56456388_56456780 0.84 Ints6l
integrator complex subunit 6 like
1699
0.29
chrX_53126124_53126420 0.82 Plac1
placental specific protein 1
11742
0.14
chr4_57294874_57295186 0.82 Gm12536
predicted gene 12536
5066
0.2
chr6_137433943_137434130 0.81 Gm44258
predicted gene, 44258
2731
0.31
chr10_84437783_84437955 0.80 Nuak1
NUAK family, SNF1-like kinase, 1
2728
0.21
chr3_105538840_105539458 0.80 Gm43847
predicted gene 43847
36242
0.16
chr7_19118025_19118835 0.80 Gm4969
predicted gene 4969
62
0.92
chr2_127521161_127522051 0.79 Kcnip3
Kv channel interacting protein 3, calsenilin
236
0.88
chr7_36708063_36708370 0.78 Gm37452
predicted gene, 37452
1958
0.24
chr3_62455854_62456272 0.78 Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
16524
0.23
chr13_60058075_60058281 0.78 Gm48396
predicted gene, 48396
553
0.74
chr3_19060318_19060537 0.78 Gm37979
predicted gene, 37979
83472
0.09
chr7_49120218_49120415 0.78 9130015G15Rik
RIKEN cDNA 9130015G15 gene
13960
0.19
chr4_89294460_89294953 0.77 Cdkn2a
cyclin dependent kinase inhibitor 2A
53
0.97
chr15_11904397_11905392 0.77 Npr3
natriuretic peptide receptor 3
745
0.59
chr17_72604337_72604548 0.76 Alk
anaplastic lymphoma kinase
135
0.97
chr1_125911939_125912615 0.76 Lypd1
Ly6/Plaur domain containing 1
63
0.98
chr14_62465099_62465250 0.76 Gucy1b2
guanylate cyclase 1, soluble, beta 2
8885
0.16
chr15_63371497_63371648 0.75 Gm41335
predicted gene, 41335
14553
0.25
chr3_88002587_88003022 0.75 Bcan
brevican
2574
0.14
chr6_72217464_72217648 0.75 Atoh8
atonal bHLH transcription factor 8
16981
0.15
chr8_119992214_119992576 0.75 Crispld2
cysteine-rich secretory protein LCCL domain containing 2
43
0.97
chr16_45724098_45724715 0.74 Tagln3
transgelin 3
202
0.92
chr11_35856666_35857239 0.74 Wwc1
WW, C2 and coiled-coil domain containing 1
3398
0.24
chr12_12680715_12680959 0.73 Gm27952
predicted gene, 27952
1781
0.32
chr5_111944661_111945068 0.73 Gm42488
predicted gene 42488
629
0.81
chr5_128684363_128684514 0.72 Piwil1
piwi-like RNA-mediated gene silencing 1
18086
0.17
chr12_79675895_79676199 0.72 9430078K24Rik
RIKEN cDNA 9430078K24 gene
248686
0.02
chr2_124244658_124244814 0.72 4930583P06Rik
RIKEN cDNA 4930583P06 gene
22405
0.26
chr3_156561488_156561966 0.72 4930570G19Rik
RIKEN cDNA 4930570G19 gene
19
0.54
chr16_35540764_35541226 0.71 Sema5b
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
150
0.95
chr5_113453534_113453685 0.71 Wscd2
WSC domain containing 2
36724
0.15
chr5_4486005_4486395 0.71 Fzd1
frizzled class receptor 1
271835
0.01
chr2_59742780_59743109 0.71 Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
142
0.98
chr1_119052750_119052942 0.70 Gli2
GLI-Kruppel family member GLI2
493
0.82
chrX_151169253_151169662 0.70 Gm15138
predicted gene 15138
243
0.89
chr1_194739874_194740294 0.70 2900035J10Rik
RIKEN cDNA 2900035J10 gene
7377
0.18
chr17_34024183_34024553 0.69 Ring1
ring finger protein 1
284
0.47
chr9_40192430_40193052 0.69 Zfp202
zinc finger protein 202
412
0.77
chr2_179571113_179571264 0.69 Gm14300
predicted gene 14300
42379
0.19
chr5_111419401_111419552 0.69 Mn1
meningioma 1
2034
0.28
chr11_96319651_96319839 0.68 Hoxb4
homeobox B4
1478
0.16
chr16_63031020_63031202 0.68 Gm18870
predicted gene, 18870
27673
0.22
chr18_7708092_7708391 0.68 Gm18763
predicted gene, 18763
15515
0.23
chr3_49592802_49593003 0.67 Gm38261
predicted gene, 38261
10659
0.16
chr1_169928593_169928926 0.67 Ccdc190
coiled-coil domain containing 190
111
0.96
chr8_47851923_47852217 0.67 Cldn22
claudin 22
27588
0.12
chr18_54452393_54453295 0.67 Gm50361
predicted gene, 50361
23921
0.19
chr3_107517941_107518419 0.67 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
162
0.95
chr15_59040434_59041094 0.66 Mtss1
MTSS I-BAR domain containing 1
167
0.96
chr4_110050502_110051534 0.66 Dmrta2
doublesex and mab-3 related transcription factor like family A2
72965
0.11
chr9_13297880_13298594 0.66 Maml2
mastermind like transcriptional coactivator 2
280
0.89
chr13_104517962_104518622 0.65 2610204G07Rik
RIKEN cDNA 2610204G07 gene
166639
0.03
chr15_80173034_80173185 0.65 Mgat3
mannoside acetylglucosaminyltransferase 3
612
0.62
chr9_68654694_68654845 0.64 Rora
RAR-related orphan receptor alpha
534
0.86
chr15_98033367_98033658 0.64 Senp1
SUMO1/sentrin specific peptidase 1
15463
0.13
chr8_126876416_126877251 0.64 Gm31718
predicted gene, 31718
395
0.86
chr4_155409110_155409311 0.64 Cfap74
cilia and flagella associated protein 74
20
0.96
chr2_79456556_79457006 0.63 Cerkl
ceramide kinase-like
4
0.51
chr6_56476694_56476845 0.63 Pde1c
phosphodiesterase 1C
92334
0.08
chr14_19808924_19809109 0.63 Nid2
nidogen 2
3780
0.19
chr17_79145323_79145513 0.62 Gm49869
predicted gene, 49869
41674
0.15
chr16_28564320_28565026 0.62 Fgf12
fibroblast growth factor 12
278
0.94
chr2_73500986_73501149 0.62 Wipf1
WAS/WASL interacting protein family, member 1
14598
0.16
chr2_12213205_12213373 0.62 Itga8
integrin alpha 8
19977
0.21
chr11_85848963_85849114 0.61 Gm11444
predicted gene 11444
1295
0.35
chr13_56260393_56260544 0.61 Neurog1
neurogenin 1
8305
0.14
chr7_18950998_18951210 0.61 Nova2
NOVA alternative splicing regulator 2
25216
0.07
chr3_97972289_97972585 0.61 Notch2
notch 2
41090
0.11
chr8_95320832_95321071 0.61 Tepp
testis, prostate and placenta expressed
455
0.73
chr12_100278057_100278346 0.61 Gm10432
predicted gene 10432
1592
0.35
chr6_32587572_32587938 0.61 Plxna4
plexin A4
437
0.86
chr3_98089829_98089980 0.61 Gm42820
predicted gene 42820
31684
0.14
chr1_31233663_31234000 0.61 Pih1d3
PIH1 domain containing 3
10993
0.12
chr1_155212206_155212458 0.60 BC034090
cDNA sequence BC034090
1649
0.31
chr19_5071354_5072731 0.60 Tmem151a
transmembrane protein 151A
90
0.61
chr2_152705710_152705861 0.60 H13
histocompatibility 13
13946
0.1
chr12_40215369_40215520 0.60 Ifrd1
interferon-related developmental regulator 1
2069
0.18
chr15_75642034_75642246 0.60 2810039B14Rik
RIKEN cDNA 2810039B14 gene
11
0.96
chr7_79607267_79607466 0.60 Rhcg
Rhesus blood group-associated C glycoprotein
507
0.65
chr7_44606194_44606370 0.59 Myh14
myosin, heavy polypeptide 14
7843
0.08
chr7_87246354_87246961 0.59 Nox4
NADPH oxidase 4
8
0.98
chr12_83044975_83045325 0.59 Rgs6
regulator of G-protein signaling 6
1840
0.38
chr2_32319526_32319750 0.59 Dnm1
dynamin 1
943
0.26
chr16_23314790_23315242 0.59 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
24546
0.16
chr19_41118445_41118596 0.59 Opalin
oligodendrocytic myelin paranodal and inner loop protein
41407
0.16
chr6_126767988_126768197 0.59 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
27418
0.13
chr13_101428003_101428155 0.59 Gm36994
predicted gene, 36994
15172
0.2
chr9_46388912_46389063 0.58 Gm47141
predicted gene, 47141
8375
0.16
chr9_72924923_72926161 0.58 Pygo1
pygopus 1
103
0.93
chrX_73659104_73659286 0.58 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
238
0.89
chrX_166585589_166585740 0.58 Egfl6
EGF-like-domain, multiple 6
56
0.98
chr1_38440241_38440470 0.57 Gm34727
predicted gene, 34727
47164
0.15
chr9_102545454_102545807 0.57 Gm25669
predicted gene, 25669
2136
0.18
chr8_54724365_54724594 0.57 Wdr17
WD repeat domain 17
5
0.98
chr5_127323908_127324249 0.57 9430087B13Rik
RIKEN cDNA 9430087B13 gene
15061
0.22
chr4_148287581_148287935 0.57 Disp3
dispatched RND transporter family member 3
207
0.93
chr14_25208311_25208849 0.57 4930572O13Rik
RIKEN cDNA 4930572O13 gene
65339
0.1
chr19_55185755_55185947 0.57 Tectb
tectorin beta
3727
0.21
chr12_110278889_110279209 0.57 Dio3
deiodinase, iodothyronine type III
19
0.91
chr7_79578778_79578997 0.57 Gm45168
predicted gene 45168
181
0.9
chr5_53258032_53258758 0.56 Smim20
small integral membrane protein 20
8688
0.19
chr5_72558899_72559546 0.56 Nfxl1
nuclear transcription factor, X-box binding-like 1
190
0.9
chr8_36155388_36156182 0.56 Gm38414
predicted gene, 38414
225
0.92
chrX_20291712_20292083 0.56 Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
90
0.97
chr7_132248145_132248298 0.55 Chst15
carbohydrate sulfotransferase 15
30404
0.15
chr11_102623865_102624274 0.55 2810433D01Rik
RIKEN cDNA 2810433D01 gene
297
0.81
chr5_71095688_71096242 0.55 Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
116
0.98
chr18_38067840_38068871 0.55 Gm30093
predicted gene, 30093
44826
0.09
chr8_103361900_103362069 0.55 1600027J07Rik
RIKEN cDNA 1600027J07 gene
14450
0.27
chr5_109552272_109552460 0.55 Gm8493
predicted gene 8493
1790
0.28
chr6_42709318_42710223 0.55 Tcaf1
TRPM8 channel-associated factor 1
301
0.81
chr4_85514095_85514441 0.55 Adamtsl1
ADAMTS-like 1
59
0.99
chr18_36069348_36069579 0.55 Nrg2
neuregulin 2
838
0.62
chr7_130264941_130265334 0.54 Fgfr2
fibroblast growth factor receptor 2
1054
0.64
chr15_75703791_75704286 0.54 Rhpn1
rhophilin, Rho GTPase binding protein 1
242
0.88
chr12_8099252_8099403 0.54 Apob
apolipoprotein B
86968
0.08
chr17_67764573_67764743 0.54 Lama1
laminin, alpha 1
47748
0.16
chr8_40669513_40669664 0.54 Adam24
a disintegrin and metallopeptidase domain 24 (testase 1)
5489
0.15
chr10_127620769_127621196 0.54 Lrp1
low density lipoprotein receptor-related protein 1
12
0.95
chr6_4902653_4902831 0.54 Ppp1r9a
protein phosphatase 1, regulatory subunit 9A
175
0.94
chr12_74284405_74285030 0.53 1700086L19Rik
RIKEN cDNA 1700086L19 gene
428
0.8
chr5_149258070_149258239 0.53 Alox5ap
arachidonate 5-lipoxygenase activating protein
6613
0.1
chr3_107460175_107460519 0.53 Kcnc4
potassium voltage gated channel, Shaw-related subfamily, member 4
795
0.62
chr1_132317450_132317859 0.53 Nuak2
NUAK family, SNF1-like kinase, 2
1489
0.28
chr19_44797376_44797743 0.53 Mir6405
microRNA 6405
10847
0.13
chrX_99141010_99141407 0.53 Efnb1
ephrin B1
3077
0.32
chr3_82903946_82904168 0.53 Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
84
0.85
chr1_167914946_167915259 0.53 Gm20711
predicted gene 20711
89037
0.1
chr4_133055540_133056727 0.53 Ahdc1
AT hook, DNA binding motif, containing 1
10116
0.19
chr15_30172351_30173308 0.53 Ctnnd2
catenin (cadherin associated protein), delta 2
138
0.98
chr6_35354569_35354998 0.52 1700065J11Rik
RIKEN cDNA 1700065J11 gene
23937
0.16
chr5_31201973_31202166 0.52 Zfp513
zinc finger protein 513
27
0.93
chr1_87187048_87187300 0.52 Chrnd
cholinergic receptor, nicotinic, delta polypeptide
3433
0.12
chr6_112865033_112865475 0.52 Srgap3
SLIT-ROBO Rho GTPase activating protein 3
35795
0.15
chr9_48737317_48737483 0.52 Zbtb16
zinc finger and BTB domain containing 16
98545
0.07
chr9_14614006_14614169 0.51 Amotl1
angiomotin-like 1
499
0.7

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Insm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0021564 vagus nerve development(GO:0021564)
0.2 0.7 GO:0033505 floor plate morphogenesis(GO:0033505)
0.2 0.7 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.2 0.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 0.6 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.2 0.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 0.5 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.3 GO:0072197 ureter morphogenesis(GO:0072197)
0.1 0.6 GO:0007412 axon target recognition(GO:0007412)
0.1 0.6 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.4 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0042851 L-alanine metabolic process(GO:0042851)
0.1 0.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 1.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.2 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282) metanephric nephron tubule formation(GO:0072289)
0.1 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.4 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.3 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.4 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.2 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0032776 DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.1 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.1 0.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.9 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.2 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.1 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.1 0.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.6 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.2 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 0.2 GO:0071926 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1 0.2 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.2 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
0.0 0.1 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.0 0.2 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.0 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.2 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:0060073 micturition(GO:0060073)
0.0 0.2 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.7 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:1901631 postsynaptic membrane assembly(GO:0097104) positive regulation of presynaptic membrane organization(GO:1901631)
0.0 0.8 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 4.0 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0071866 regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0 0.2 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 1.1 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.3 GO:0071435 potassium ion export(GO:0071435)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0 0.1 GO:0060453 regulation of gastric acid secretion(GO:0060453) negative regulation of gastric acid secretion(GO:0060455)
0.0 0.6 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:0072050 S-shaped body morphogenesis(GO:0072050)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0051589 negative regulation of neurotransmitter transport(GO:0051589)
0.0 0.5 GO:2001258 negative regulation of cation channel activity(GO:2001258)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.2 GO:0048265 response to pain(GO:0048265)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.7 GO:0097061 dendritic spine organization(GO:0097061)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0015810 aspartate transport(GO:0015810)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.0 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0042044 fluid transport(GO:0042044)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:1903802 L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.2 GO:1903392 negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0010388 protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.0 0.0 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.0 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0098764 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.0 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:2001260 regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.0 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 1.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.0 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.0 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:1900113 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:0033058 directional locomotion(GO:0033058)
0.0 0.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.0 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.3 GO:0070873 regulation of glycogen metabolic process(GO:0070873)
0.0 0.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.0 GO:0014044 Schwann cell development(GO:0014044)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.0 GO:0097490 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.1 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.2 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.0 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.0 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) vitamin D3 metabolic process(GO:0070640)
0.0 0.0 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.0 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.0 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.0 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.0 GO:0060278 regulation of ovulation(GO:0060278)
0.0 0.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.8 GO:0097542 ciliary tip(GO:0097542)
0.1 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.7 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.2 GO:0097433 dense body(GO:0097433)
0.1 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0071546 pi-body(GO:0071546)
0.1 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 4.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.0 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.7 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.0 1.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0038064 collagen receptor activity(GO:0038064)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0080014 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0019198 transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0015172 acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.0 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins