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ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Isl1

Z-value: 10.05

Motif logo

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Transcription factors associated with Isl1

Gene Symbol Gene ID Gene Info
ENSMUSG00000042258.7 Isl1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Isl1chr13_116305222_11630537311000.5698570.804.0e-13Click!
Isl1chr13_116297196_11629734760800.2489850.711.5e-09Click!
Isl1chr13_116309234_116309535380.9812950.702.8e-09Click!
Isl1chr13_116304768_11630505814840.4633140.695.5e-09Click!
Isl1chr13_116293962_11629416292890.2369790.582.7e-06Click!

Activity of the Isl1 motif across conditions

Conditions sorted by the z-value of the Isl1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_64595318_64595919 33.85 Mir3078
microRNA 3078
4433
0.18
chr13_39524261_39524439 33.21 Gm47351
predicted gene, 47351
8753
0.2
chr5_149527921_149528686 33.19 Wdr95
WD40 repeat domain 95
376
0.81
chrX_13346707_13347908 29.20 Gm7129
predicted gene 7129
20288
0.14
chr18_81830833_81831208 28.62 Gm30454
predicted gene, 30454
18996
0.19
chr4_65888333_65888871 26.62 Trim32
tripartite motif-containing 32
283353
0.01
chr6_96286333_96286534 25.84 1700123L14Rik
RIKEN cDNA 1700123L14 gene
120190
0.06
chr5_85239463_85240008 25.43 Gm21006
predicted gene, 21006
372890
0.01
chr18_45896851_45897467 25.33 A330093E20Rik
RIKEN cDNA A330093E20 gene
650
0.79
chr2_43978848_43979182 25.13 Arhgap15
Rho GTPase activating protein 15
86026
0.1
chr3_66326110_66326323 25.06 Veph1
ventricular zone expressed PH domain-containing 1
29379
0.18
chr8_61325062_61325301 24.57 1700001D01Rik
RIKEN cDNA 1700001D01 gene
36309
0.13
chr9_15866407_15866579 24.50 Mtnr1b
melatonin receptor 1B
7967
0.23
chr7_109165964_109166186 23.95 Lmo1
LIM domain only 1
4437
0.2
chr11_58400392_58400572 23.95 Gm12252
predicted gene 12252
3967
0.11
chr2_35849935_35850217 23.55 Gm10829
predicted gene 10829
5881
0.2
chr3_40070102_40070729 23.40 Gm42785
predicted gene 42785
246838
0.02
chr2_21060324_21060508 23.09 Gm13376
predicted gene 13376
36683
0.16
chr4_79530917_79531075 22.98 Gm11263
predicted gene 11263
203288
0.03
chr10_92162409_92163019 22.20 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
47
0.98
chr8_45508006_45508255 22.07 Sorbs2
sorbin and SH3 domain containing 2
212
0.94
chr13_83749525_83749738 22.05 C130071C03Rik
RIKEN cDNA C130071C03 gene
10768
0.12
chr4_71484616_71485009 21.71 Rps18-ps1
ribosomal protein S18, pseudogene 1
113616
0.07
chr10_16052455_16052829 21.29 C330004P14Rik
RIKEN cDNA C330004P14 gene
260865
0.02
chr1_192755693_192756022 21.19 Gm22265
predicted gene, 22265
10286
0.17
chr8_33747412_33747586 21.05 Smim18
small integral membrane protein 18
271
0.88
chr17_76111639_76112128 20.94 Gm24126
predicted gene, 24126
37337
0.22
chr5_35454198_35454812 20.89 Gm43377
predicted gene 43377
58407
0.08
chr3_45385015_45385410 20.40 Pcdh10
protocadherin 10
2579
0.24
chr1_51650752_51650944 20.31 Gm28055
predicted gene 28055
47052
0.14
chr3_68824497_68825036 20.28 Gm7270
predicted gene 7270
21313
0.12
chr12_44839950_44840386 20.21 Gm15901
predicted gene 15901
83012
0.1
chr10_37378009_37378297 20.19 Gm26535
predicted gene, 26535
40667
0.19
chr12_17048993_17049526 20.11 Gm48538
predicted gene, 48538
16154
0.17
chr17_9543267_9543689 19.80 Gm49807
predicted gene, 49807
6213
0.28
chr7_92258664_92258972 19.72 Dlg2
discs large MAGUK scaffold protein 2
23691
0.23
chr19_26770137_26770516 19.70 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
165
0.96
chr16_89538151_89538450 19.61 Krtap7-1
keratin associated protein 7-1
29977
0.13
chr10_52742737_52743261 19.54 Gm47624
predicted gene, 47624
49161
0.11
chr2_146724257_146724438 19.50 Gm14111
predicted gene 14111
31358
0.22
chr3_127294086_127294512 19.19 Gm42970
predicted gene 42970
5374
0.15
chr13_72028642_72028801 19.15 Irx1
Iroquois homeobox 1
64998
0.13
chr16_25016242_25016817 19.03 A230028O05Rik
RIKEN cDNA A230028O05 gene
43110
0.19
chr2_63963076_63963322 18.76 Fign
fidgetin
134789
0.06
chr13_83661208_83661451 18.70 Mef2c
myocyte enhancer factor 2C
8441
0.18
chr15_50735926_50736259 18.45 Trps1
transcriptional repressor GATA binding 1
91429
0.09
chr8_61515184_61515647 18.43 Palld
palladin, cytoskeletal associated protein
485
0.84
chr6_49021447_49021653 18.31 Gpnmb
glycoprotein (transmembrane) nmb
14996
0.08
chr9_90693284_90693632 18.31 Gm2497
predicted gene 2497
40066
0.15
chr18_57262231_57262735 18.28 Gm50200
predicted gene, 50200
52657
0.11
chr18_40796377_40796528 18.25 Rps19-ps13
ribosomal protein S19, pseudogene 13
70183
0.11
chr11_47264465_47264671 18.23 Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
114954
0.07
chr8_78556826_78557206 18.20 Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
20735
0.18
chr5_9345097_9345292 18.20 Gm15733
predicted gene 15733
8565
0.2
chr15_37135024_37136161 18.11 Gm9509
predicted gene 9509
36812
0.14
chr7_49699439_49699606 18.00 Htatip2
HIV-1 Tat interactive protein 2
59593
0.11
chr7_88261931_88262082 17.91 Ctsc
cathepsin C
16079
0.22
chr16_63278367_63278696 17.77 Gm33912
predicted gene, 33912
61089
0.15
chr11_82579895_82580440 17.76 Gm24612
predicted gene, 24612
16012
0.2
chr17_66869624_66870037 17.75 Gm49940
predicted gene, 49940
7590
0.18
chrX_101987046_101987197 17.73 Nhsl2
NHS-like 2
17923
0.15
chr13_58971668_58972019 17.72 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
100108
0.06
chr15_36967359_36968246 17.72 Gm34590
predicted gene, 34590
28938
0.13
chr2_10525644_10525960 17.70 Mir669h
microRNA 669h
7647
0.01
chr17_78501306_78501507 17.60 Vit
vitrin
6658
0.17
chr3_102980219_102980386 17.51 Sike1
suppressor of IKBKE 1
15406
0.12
chr4_55929493_55929703 17.43 Gm12519
predicted gene 12519
64141
0.14
chrX_161524009_161524161 17.41 Prkaca-ps1
protein kinase, cAMP dependent, catalytic, alpha pseudogene 1
37600
0.22
chr13_6306939_6307331 17.26 Gm35615
predicted gene, 35615
12421
0.23
chr3_145825482_145825700 17.24 Ddah1
dimethylarginine dimethylaminohydrolase 1
15112
0.2
chr16_39287252_39287499 17.20 Gm36742
predicted gene, 36742
98469
0.08
chr7_131778146_131778326 17.18 Gm44547
predicted gene 44547
8343
0.22
chr13_28295576_28295772 17.14 Gm47172
predicted gene, 47172
10105
0.23
chr9_84253597_84253862 17.10 Gm26146
predicted gene, 26146
65374
0.12
chr8_45507619_45508001 16.90 Sorbs2
sorbin and SH3 domain containing 2
2
0.98
chr16_42339557_42339849 16.89 Gap43
growth associated protein 43
948
0.66
chr6_47228750_47229021 16.73 Cntnap2
contactin associated protein-like 2
15502
0.28
chr2_105674521_105675719 16.64 Pax6
paired box 6
11
0.97
chr18_42704653_42704822 16.51 C030004G16Rik
RIKEN cDNA C030004G16 gene
82278
0.08
chr6_77243554_77244106 16.49 Lrrtm1
leucine rich repeat transmembrane neuronal 1
908
0.69
chr3_104058968_104059448 16.48 Gm42696
predicted gene 42696
1067
0.33
chr2_181766899_181767258 16.43 Myt1
myelin transcription factor 1
36
0.97
chr6_5408845_5409023 16.43 Asb4
ankyrin repeat and SOCS box-containing 4
18507
0.23
chr9_71879542_71879779 16.37 Tcf12
transcription factor 12
5051
0.13
chr12_56458764_56459233 16.33 Sfta3-ps
surfactant associated 3, pseudogene
34326
0.12
chr17_43158272_43158631 16.14 E130008D07Rik
RIKEN cDNA E130008D07 gene
160
0.97
chr4_71485302_71485664 16.10 Rps18-ps1
ribosomal protein S18, pseudogene 1
114287
0.07
chr13_56774410_56774604 16.07 Gm45623
predicted gene 45623
20680
0.21
chr6_8294057_8294761 16.03 Umad1
UMAP1-MVP12 associated (UMA) domain containing 1
23943
0.14
chr18_30197602_30197916 15.91 Gm49980
predicted gene, 49980
69490
0.12
chr13_34129793_34130880 15.86 Tubb2b
tubulin, beta 2B class IIB
18
0.96
chr12_58670274_58670654 15.85 Gm18873
predicted gene, 18873
93442
0.08
chr6_8352593_8352826 15.75 Gm16055
predicted gene 16055
11427
0.18
chr12_77739490_77739672 15.65 4930458K08Rik
RIKEN cDNA 4930458K08 gene
56520
0.12
chr7_73637071_73637452 15.58 Gm44737
predicted gene 44737
6644
0.1
chr3_26835054_26835226 15.53 Gm37659
predicted gene, 37659
177624
0.03
chr6_32373945_32374204 15.51 Plxna4os3
plexin A4, opposite strand 3
70161
0.11
chr2_64706718_64706919 15.47 Gm13576
predicted gene 13576
136178
0.05
chr3_26641406_26641733 15.30 Spata16
spermatogenesis associated 16
3919
0.29
chr14_46077518_46077669 15.30 Ubb-ps
ubiquitin B, pseudogene
6435
0.2
chr15_10421430_10421775 15.29 Dnajc21
DnaJ heat shock protein family (Hsp40) member C21
28390
0.15
chr2_74426718_74427115 15.25 Lnpk
lunapark, ER junction formation factor
106190
0.05
chr4_110209740_110209990 15.22 Elavl4
ELAV like RNA binding protein 4
13283
0.29
chr6_98046634_98046821 15.20 Mitf
melanogenesis associated transcription factor
54806
0.15
chr14_35095601_35095765 15.18 Gm49034
predicted gene, 49034
123755
0.06
chr11_24363754_24364273 15.17 Gm12068
predicted gene 12068
62233
0.12
chr7_19175722_19176163 15.14 Eml2
echinoderm microtubule associated protein like 2
479
0.59
chr10_23016379_23016546 15.01 Gm47787
predicted gene, 47787
59878
0.13
chr3_17616549_17616970 14.94 Gm38154
predicted gene, 38154
53929
0.16
chr6_58837806_58838284 14.94 Herc3
hect domain and RLD 3
4345
0.25
chr15_103519338_103519794 14.88 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
4152
0.16
chr9_124439329_124439899 14.84 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
1254
0.4
chr11_71414747_71415135 14.80 Gm16013
predicted gene 16013
21239
0.21
chr12_5144239_5144620 14.76 Gm9110
predicted gene 9110
76981
0.09
chr13_83984413_83984945 14.72 Gm4241
predicted gene 4241
3312
0.25
chr10_87486341_87486591 14.70 Ascl1
achaete-scute family bHLH transcription factor 1
7194
0.2
chr16_63806861_63807216 14.68 Epha3
Eph receptor A3
56375
0.15
chr19_14777197_14777401 14.64 Gm26026
predicted gene, 26026
58819
0.15
chr5_42068234_42068511 14.59 Gm16223
predicted gene 16223
412
0.91
chr13_76802462_76802613 14.58 Mctp1
multiple C2 domains, transmembrane 1
22670
0.24
chr16_77537354_77537608 14.57 Gm36963
predicted gene, 36963
2401
0.2
chr1_127531215_127531971 14.55 Tmem163
transmembrane protein 163
5837
0.29
chr3_31309752_31310443 14.47 Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
281
0.81
chr8_31091237_31091775 14.46 Dusp26
dual specificity phosphatase 26 (putative)
144
0.96
chr9_52278418_52278613 14.45 Gm25562
predicted gene, 25562
12684
0.22
chr6_22834243_22834395 14.42 Gm43629
predicted gene 43629
28990
0.15
chr2_130352053_130352242 14.40 Gm14044
predicted gene 14044
33182
0.07
chr2_144127511_144127732 14.38 Gm11687
predicted gene 11687
15752
0.16
chr12_33035669_33036432 14.31 Cdhr3
cadherin-related family member 3
16936
0.14
chr7_62046082_62046717 14.28 Mir344f
microRNA Mir344f
151
0.94
chr10_27468497_27468689 14.28 Gm23353
predicted gene, 23353
16304
0.24
chr2_62047014_62047411 14.22 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
567
0.84
chr10_104686774_104686997 14.18 Gm25522
predicted gene, 25522
178423
0.03
chr4_28935550_28935919 14.16 Epha7
Eph receptor A7
63810
0.13
chr9_27298463_27299015 14.13 Igsf9b
immunoglobulin superfamily, member 9B
465
0.82
chr7_112535354_112535706 14.12 Parvaos
parvin, alpha, opposite strand
153
0.96
chr10_39227529_39227710 14.11 Gm31562
predicted gene, 31562
17427
0.16
chr7_51784054_51784235 14.01 Gm29296
predicted gene 29296
11418
0.17
chr13_79430948_79431368 14.01 Gm48470
predicted gene, 48470
10249
0.24
chr5_112481948_112482441 13.98 Sez6l
seizure related 6 homolog like
7067
0.17
chr18_23394845_23395028 13.95 Dtna
dystrobrevin alpha
20199
0.27
chr3_85764601_85764835 13.94 Fam160a1
family with sequence similarity 160, member A1
18452
0.2
chr2_97478952_97479288 13.91 Lrrc4c
leucine rich repeat containing 4C
11031
0.3
chr2_179481364_179481534 13.88 Cdh4
cadherin 4
37216
0.18
chr14_75566269_75566669 13.88 Cby2
chibby family member 2
25480
0.19
chr4_110153152_110153342 13.79 Elavl4
ELAV like RNA binding protein 4
69901
0.13
chr2_146723162_146723336 13.77 Gm14111
predicted gene 14111
32456
0.21
chr1_18191166_18191317 13.75 Defb44-ps
defensin beta 44, pseudogene
32323
0.14
chr11_117454302_117454453 13.75 Gm11732
predicted gene 11732
28199
0.11
chr3_8510380_8510590 13.73 Stmn2
stathmin-like 2
899
0.63
chr5_111220876_111221370 13.72 Ttc28
tetratricopeptide repeat domain 28
4335
0.22
chr3_62454253_62454452 13.71 Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
18235
0.22
chr18_74956461_74956661 13.69 Lipg
lipase, endothelial
4701
0.11
chr13_84571624_84571828 13.67 Gm26913
predicted gene, 26913
119215
0.06
chr4_120332877_120333106 13.65 Foxo6os
forkhead box O6, opposite strand
41641
0.15
chr7_61939801_61940302 13.64 Mir344-2
microRNA 344-2
55
0.95
chr4_110287470_110287673 13.63 Elavl4
ELAV like RNA binding protein 4
44
0.99
chr2_109678555_109678726 13.62 Bdnf
brain derived neurotrophic factor
1608
0.32
chr12_46520967_46521283 13.52 Gm7422
predicted gene 7422
41798
0.18
chr9_94410108_94410502 13.48 Gm5370
predicted gene 5370
2179
0.35
chr2_10293635_10293822 13.48 Sfmbt2
Scm-like with four mbt domains 2
76782
0.03
chr12_120015533_120015684 13.47 Gm27236
predicted gene 27236
15081
0.24
chr11_35203810_35203973 13.46 Gm26070
predicted gene, 26070
10510
0.24
chr14_104298418_104298592 13.45 D130079A08Rik
RIKEN cDNA D130079A08 gene
160811
0.04
chr15_8659976_8660428 13.41 Gm37310
predicted gene, 37310
5129
0.23
chr8_86389721_86389961 13.39 Gm24490
predicted gene, 24490
97340
0.07
chr9_10681606_10682000 13.36 Gm7529
predicted gene 7529
52837
0.17
chr1_51216342_51216995 13.36 Gm29325
predicted gene 29325
21447
0.19
chr15_66239660_66240017 13.33 Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
46213
0.14
chr9_37625246_37625717 13.32 Siae
sialic acid acetylesterase
3827
0.14
chr9_105379897_105380048 13.31 Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
13049
0.16
chrX_110318504_110318684 13.31 Gm7134
predicted gene 7134
54159
0.18
chr8_112268552_112269162 13.30 Gm3635
predicted gene 3635
31891
0.23
chr5_147155070_147155280 13.30 Gsx1
GS homeobox 1
33521
0.11
chr11_16299934_16300272 13.27 Vstm2a
V-set and transmembrane domain containing 2A
36885
0.19
chr6_47239363_47240145 13.18 Cntnap2
contactin associated protein-like 2
4633
0.33
chr6_148615895_148616290 13.18 Gm6313
predicted gene 6313
1783
0.35
chr4_151696178_151696329 13.16 Camta1
calmodulin binding transcription activator 1
165397
0.03
chr10_30327889_30328266 13.15 Gm4780
predicted gene 4780
44841
0.17
chr4_87651182_87651681 13.14 Gm12604
predicted gene 12604
70642
0.13
chr5_103160967_103161542 13.12 Mapk10
mitogen-activated protein kinase 10
44675
0.17
chr4_88211578_88211756 13.11 Gm12645
predicted gene 12645
59971
0.11
chr16_77648330_77648508 13.10 C130023A14Rik
RIKEN cDNA C130023A14 gene
2079
0.17
chr8_67972439_67972650 13.09 Psd3
pleckstrin and Sec7 domain containing 3
2030
0.35
chr16_49193672_49193981 13.07 1700026J12Rik
RIKEN cDNA 1700026J12 gene
61946
0.12
chr11_112869991_112870994 13.06 4933434M16Rik
RIKEN cDNA 4933434M16 gene
45313
0.16
chr15_88360840_88360991 13.04 4930445N06Rik
RIKEN cDNA 4930445N06 gene
45283
0.16
chr10_36534044_36534213 13.02 Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
26721
0.24
chr13_21005724_21006043 13.01 Aoah
acyloxyacyl hydrolase
4750
0.24
chr16_51589915_51590114 12.99 Gm49608
predicted gene, 49608
173066
0.04
chrX_69666420_69666593 12.99 Gm8172
predicted pseudogene 8172
60261
0.15
chr8_74557794_74557991 12.98 Gm11033
predicted gene 11033
276028
0.01
chr10_23449639_23449790 12.97 Eya4
EYA transcriptional coactivator and phosphatase 4
98928
0.07
chr5_111725288_111725497 12.96 Gm26897
predicted gene, 26897
8532
0.19
chr2_60654945_60655277 12.96 Itgb6
integrin beta 6
18582
0.2
chr2_94246412_94247550 12.96 Mir670hg
MIR670 host gene (non-protein coding)
3643
0.17
chr1_31233663_31234000 12.94 Pih1d3
PIH1 domain containing 3
10993
0.12
chr12_51081982_51082133 12.93 Gm22088
predicted gene, 22088
3630
0.28
chr1_57862082_57862411 12.92 Spats2l
spermatogenesis associated, serine-rich 2-like
16675
0.22
chr13_85067648_85067905 12.92 Gm47745
predicted gene, 47745
26559
0.17

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Isl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.5 62.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
9.9 29.8 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
9.1 27.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
8.9 26.6 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
8.7 26.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
8.4 33.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
7.3 51.3 GO:0016198 axon choice point recognition(GO:0016198)
6.8 20.4 GO:0003358 noradrenergic neuron development(GO:0003358)
5.8 17.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
5.6 16.7 GO:0060178 regulation of exocyst localization(GO:0060178)
5.3 21.2 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
4.7 14.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
4.6 13.9 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
4.6 4.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.5 4.5 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107)
4.2 21.2 GO:0021764 amygdala development(GO:0021764)
4.2 16.6 GO:0016576 histone dephosphorylation(GO:0016576)
4.0 12.0 GO:0032289 central nervous system myelin formation(GO:0032289)
4.0 31.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.9 15.6 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
3.9 11.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
3.8 11.5 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
3.8 7.6 GO:0061642 chemoattraction of axon(GO:0061642)
3.8 18.9 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
3.8 15.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
3.7 11.2 GO:0072240 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
3.7 18.6 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
3.7 11.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
3.7 11.0 GO:0007525 somatic muscle development(GO:0007525)
3.6 10.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
3.6 32.2 GO:0021859 pyramidal neuron differentiation(GO:0021859)
3.5 17.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.5 13.9 GO:0007258 JUN phosphorylation(GO:0007258)
3.4 10.3 GO:0030070 insulin processing(GO:0030070)
3.4 20.6 GO:0071625 vocalization behavior(GO:0071625)
3.4 10.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
3.4 10.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
3.3 3.3 GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
3.2 13.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
3.2 9.7 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
3.2 9.6 GO:0098904 regulation of AV node cell action potential(GO:0098904)
3.2 12.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
3.2 12.7 GO:0098598 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
3.2 9.5 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
3.2 15.8 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
3.1 3.1 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
3.1 24.7 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
3.0 3.0 GO:0021861 forebrain radial glial cell differentiation(GO:0021861) auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
3.0 21.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
3.0 9.0 GO:0035106 operant conditioning(GO:0035106)
3.0 18.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
3.0 6.0 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
3.0 3.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
3.0 11.9 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
2.9 2.9 GO:0022038 corpus callosum development(GO:0022038)
2.9 8.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.8 16.8 GO:0098828 modulation of inhibitory postsynaptic potential(GO:0098828)
2.8 8.4 GO:0060594 mammary gland specification(GO:0060594)
2.8 8.4 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.8 13.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
2.7 8.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.7 8.1 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
2.7 18.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
2.6 10.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
2.5 7.4 GO:0099558 maintenance of synapse structure(GO:0099558)
2.4 7.3 GO:0021564 vagus nerve development(GO:0021564)
2.4 7.3 GO:1990034 calcium ion export from cell(GO:1990034)
2.4 16.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
2.4 4.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
2.4 7.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
2.4 7.1 GO:0072092 ureteric bud invasion(GO:0072092)
2.4 2.4 GO:0021631 optic nerve morphogenesis(GO:0021631)
2.3 2.3 GO:0021550 medulla oblongata development(GO:0021550)
2.3 7.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
2.3 9.2 GO:0060513 prostatic bud formation(GO:0060513)
2.3 6.9 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
2.3 4.5 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
2.3 6.8 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
2.2 2.2 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.2 49.2 GO:0035418 protein localization to synapse(GO:0035418)
2.2 20.0 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
2.2 6.6 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
2.2 6.5 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578) gamma-aminobutyric acid receptor clustering(GO:0097112)
2.2 6.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
2.1 2.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
2.1 8.3 GO:0043587 tongue morphogenesis(GO:0043587)
2.1 2.1 GO:1904861 excitatory synapse assembly(GO:1904861)
2.0 12.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
2.0 16.3 GO:0050957 equilibrioception(GO:0050957)
2.0 12.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
2.0 4.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.0 2.0 GO:0097212 lysosomal membrane organization(GO:0097212)
2.0 10.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
2.0 6.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
2.0 7.9 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
2.0 7.9 GO:1903887 motile primary cilium assembly(GO:1903887)
2.0 11.7 GO:0021559 trigeminal nerve development(GO:0021559)
1.9 5.8 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.9 5.8 GO:0001927 exocyst assembly(GO:0001927)
1.9 3.9 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
1.9 11.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.9 5.8 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
1.9 5.7 GO:0030035 microspike assembly(GO:0030035)
1.9 5.7 GO:0072318 clathrin coat disassembly(GO:0072318)
1.9 13.3 GO:0005513 detection of calcium ion(GO:0005513)
1.9 5.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
1.9 31.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
1.9 1.9 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
1.9 1.9 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.8 9.1 GO:0019532 oxalate transport(GO:0019532)
1.8 1.8 GO:1902669 positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
1.8 16.2 GO:0021542 dentate gyrus development(GO:0021542)
1.8 10.6 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
1.8 7.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.8 5.3 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
1.8 5.3 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.7 7.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.7 3.5 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
1.7 5.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
1.7 5.2 GO:2000599 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
1.7 5.1 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
1.7 6.8 GO:0060279 positive regulation of ovulation(GO:0060279)
1.7 11.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.7 18.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
1.7 25.2 GO:0016082 synaptic vesicle priming(GO:0016082)
1.7 5.0 GO:0035262 gonad morphogenesis(GO:0035262)
1.6 6.6 GO:0002051 osteoblast fate commitment(GO:0002051)
1.6 4.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.6 9.8 GO:0086014 atrial cardiac muscle cell action potential(GO:0086014) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
1.6 1.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.6 8.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.6 4.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.6 3.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.6 11.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.6 11.0 GO:0060539 diaphragm development(GO:0060539)
1.6 7.8 GO:1902774 late endosome to lysosome transport(GO:1902774)
1.6 4.7 GO:0007638 mechanosensory behavior(GO:0007638)
1.6 3.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
1.5 4.6 GO:0006597 spermine biosynthetic process(GO:0006597)
1.5 9.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.5 15.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.5 82.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.5 7.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.5 4.5 GO:1900368 regulation of RNA interference(GO:1900368)
1.5 3.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.5 28.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.5 3.0 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
1.5 5.9 GO:0014042 positive regulation of neuron maturation(GO:0014042)
1.4 14.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
1.4 1.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.4 4.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.4 1.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
1.4 7.0 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
1.4 5.6 GO:0048664 neuron fate determination(GO:0048664)
1.4 2.8 GO:0090135 actin filament branching(GO:0090135)
1.4 5.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
1.4 4.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.4 5.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.4 4.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.4 5.5 GO:0006041 glucosamine metabolic process(GO:0006041)
1.4 104.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.4 12.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.4 2.7 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
1.4 2.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.4 4.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.4 6.8 GO:0030432 peristalsis(GO:0030432)
1.3 2.7 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
1.3 5.4 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
1.3 10.7 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.3 2.6 GO:0071435 potassium ion export(GO:0071435)
1.3 6.6 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.3 5.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.3 3.9 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
1.3 2.6 GO:0021553 olfactory nerve development(GO:0021553)
1.3 3.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.3 3.9 GO:0014732 skeletal muscle atrophy(GO:0014732)
1.3 10.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
1.3 5.1 GO:0031642 negative regulation of myelination(GO:0031642)
1.3 3.8 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.3 3.8 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.3 5.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
1.3 3.8 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.3 3.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.2 1.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.2 7.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
1.2 2.5 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
1.2 1.2 GO:1901671 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
1.2 3.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.2 2.4 GO:0060166 olfactory pit development(GO:0060166)
1.2 8.6 GO:0006108 malate metabolic process(GO:0006108)
1.2 2.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.2 3.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.2 4.9 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.2 4.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.2 4.8 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.2 9.5 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
1.2 2.4 GO:0097070 ductus arteriosus closure(GO:0097070)
1.2 2.4 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
1.2 2.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.2 2.4 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.2 5.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.2 8.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.2 14.0 GO:0016486 peptide hormone processing(GO:0016486)
1.2 1.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
1.2 7.0 GO:0070314 G1 to G0 transition(GO:0070314)
1.2 2.3 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
1.2 2.3 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.2 3.5 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.1 2.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
1.1 9.0 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
1.1 3.4 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.1 3.4 GO:0023041 neuronal signal transduction(GO:0023041)
1.1 3.3 GO:0060437 lung growth(GO:0060437)
1.1 2.2 GO:0042940 D-amino acid transport(GO:0042940)
1.1 3.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.1 13.3 GO:0051654 establishment of mitochondrion localization(GO:0051654)
1.1 1.1 GO:0021825 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166) facioacoustic ganglion development(GO:1903375) dorsal root ganglion development(GO:1990791)
1.1 2.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
1.1 4.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.1 3.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1 7.5 GO:0035641 locomotory exploration behavior(GO:0035641)
1.1 6.5 GO:0006642 triglyceride mobilization(GO:0006642)
1.1 18.3 GO:0001964 startle response(GO:0001964)
1.1 5.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
1.1 2.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
1.1 6.4 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
1.1 5.3 GO:0009235 cobalamin metabolic process(GO:0009235)
1.1 2.1 GO:0001757 somite specification(GO:0001757)
1.1 3.2 GO:0051684 maintenance of Golgi location(GO:0051684)
1.1 4.2 GO:0042473 outer ear morphogenesis(GO:0042473)
1.1 6.4 GO:0060179 male mating behavior(GO:0060179)
1.1 10.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
1.0 3.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
1.0 2.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
1.0 2.1 GO:0046098 guanine metabolic process(GO:0046098)
1.0 3.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.0 8.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.0 2.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
1.0 3.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
1.0 7.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
1.0 7.0 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
1.0 1.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.0 1.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
1.0 3.9 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.0 3.0 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.0 5.9 GO:0090527 actin filament reorganization(GO:0090527)
1.0 2.9 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.0 2.0 GO:0035826 rubidium ion transport(GO:0035826)
1.0 6.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
1.0 3.9 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
1.0 3.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.0 2.9 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.0 2.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
1.0 6.7 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
1.0 1.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.9 3.8 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.9 2.8 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.9 2.8 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.9 1.9 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.9 0.9 GO:0061110 dense core granule biogenesis(GO:0061110)
0.9 6.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.9 3.7 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.9 2.7 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.9 5.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.9 2.7 GO:0010046 response to mycotoxin(GO:0010046)
0.9 1.8 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.9 0.9 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) negative regulation of purine nucleotide catabolic process(GO:0033122) regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.9 1.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.9 1.8 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.9 5.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.9 3.6 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.9 22.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.9 74.4 GO:0007612 learning(GO:0007612)
0.9 2.7 GO:0003139 secondary heart field specification(GO:0003139)
0.9 15.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.9 1.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.9 3.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.9 8.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.8 2.5 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.8 1.7 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.8 2.5 GO:0060005 vestibular reflex(GO:0060005)
0.8 2.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8 2.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.8 1.7 GO:0060676 ureteric bud formation(GO:0060676)
0.8 2.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.8 9.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.8 2.5 GO:0061511 centriole elongation(GO:0061511)
0.8 6.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.8 1.6 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.8 5.7 GO:0021544 subpallium development(GO:0021544)
0.8 0.8 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.8 7.2 GO:0001504 neurotransmitter uptake(GO:0001504)
0.8 1.6 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.8 0.8 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.8 0.8 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.8 1.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.8 2.4 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.8 0.8 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.8 1.6 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.8 1.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.8 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.8 1.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.8 5.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.8 7.6 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.8 2.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.8 4.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.7 2.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.7 5.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.7 2.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.7 1.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.7 0.7 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.7 1.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.7 1.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.7 6.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.7 0.7 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.7 2.1 GO:0032808 lacrimal gland development(GO:0032808)
0.7 1.4 GO:0035907 dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.7 3.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.7 2.1 GO:0001834 trophectodermal cell proliferation(GO:0001834)
0.7 2.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.7 2.7 GO:0035428 hexose transmembrane transport(GO:0035428)
0.7 2.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.7 11.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7 3.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.7 1.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.7 1.3 GO:0060463 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.7 4.7 GO:0097237 cellular response to toxic substance(GO:0097237)
0.7 2.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.7 1.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.7 0.7 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.7 2.0 GO:1903975 regulation of glial cell migration(GO:1903975)
0.7 12.4 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.7 3.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.7 13.7 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.6 4.5 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.6 1.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.6 2.6 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.6 3.2 GO:0071397 cellular response to cholesterol(GO:0071397)
0.6 1.3 GO:0070253 somatostatin secretion(GO:0070253)
0.6 3.1 GO:2000617 positive regulation of histone H3-K9 acetylation(GO:2000617)
0.6 1.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.6 6.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 1.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.6 4.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 1.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.6 3.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.6 8.5 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.6 0.6 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.6 0.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.6 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.6 0.6 GO:0021586 pons maturation(GO:0021586)
0.6 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.6 1.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.6 1.2 GO:0021548 pons development(GO:0021548)
0.6 2.9 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.6 3.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.6 1.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.6 6.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 0.6 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.6 2.3 GO:0051013 microtubule severing(GO:0051013)
0.6 1.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.6 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.6 2.2 GO:0006742 NADP catabolic process(GO:0006742)
0.6 3.4 GO:0015074 DNA integration(GO:0015074)
0.6 2.2 GO:0090148 membrane fission(GO:0090148)
0.6 15.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.6 5.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.6 3.3 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.5 1.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.5 3.8 GO:0006983 ER overload response(GO:0006983)
0.5 2.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 2.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.5 1.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.5 1.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 0.5 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.5 0.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.5 0.5 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 0.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.5 1.5 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.5 1.0 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.5 5.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.5 1.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.5 3.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 3.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.5 1.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.5 1.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.5 1.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.5 1.4 GO:0021794 thalamus development(GO:0021794)
0.5 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 1.4 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.5 0.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 15.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.5 1.8 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.5 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.5 0.9 GO:0072173 metanephric tubule morphogenesis(GO:0072173)
0.4 3.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.4 6.2 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.4 1.3 GO:0019086 late viral transcription(GO:0019086)
0.4 0.9 GO:0009106 lipoate metabolic process(GO:0009106)
0.4 0.4 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.4 0.9 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.4 0.9 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4 6.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.4 1.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.4 1.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 1.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.4 1.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.4 3.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 1.7 GO:0030091 protein repair(GO:0030091)
0.4 0.4 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.4 2.5 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4 1.2 GO:0006553 lysine metabolic process(GO:0006553)
0.4 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 2.4 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 0.8 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.4 4.0 GO:0009404 toxin metabolic process(GO:0009404)
0.4 0.8 GO:0014029 neural crest formation(GO:0014029)
0.4 5.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 1.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.4 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.4 2.8 GO:0007135 meiosis II(GO:0007135)
0.4 0.8 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.4 1.2 GO:0030421 defecation(GO:0030421)
0.4 1.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.4 1.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.4 3.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.4 1.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4 2.3 GO:0042474 middle ear morphogenesis(GO:0042474)
0.4 0.4 GO:0060278 regulation of ovulation(GO:0060278)
0.4 1.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 2.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.4 3.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 0.4 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.4 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.4 1.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.4 1.5 GO:0003352 regulation of cilium movement(GO:0003352)
0.4 0.4 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.4 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.4 0.4 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.4 0.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.4 0.7 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 1.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.4 1.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.4 0.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.4 1.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 1.4 GO:0003416 endochondral bone growth(GO:0003416)
0.4 0.4 GO:0021554 optic nerve development(GO:0021554)
0.4 0.4 GO:0040031 snRNA modification(GO:0040031)
0.4 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 5.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 2.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 0.7 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.3 1.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.3 0.7 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.3 0.3 GO:1901858 regulation of mitochondrial DNA metabolic process(GO:1901858)
0.3 0.3 GO:0072205 metanephric collecting duct development(GO:0072205)
0.3 1.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 0.7 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
0.3 1.0 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.3 5.6 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.3 1.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.3 4.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.3 1.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 2.6 GO:0071436 sodium ion export(GO:0071436)
0.3 1.0 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 0.3 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.3 1.3 GO:0002063 chondrocyte development(GO:0002063)
0.3 1.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.3 0.6 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.3 1.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 0.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.9 GO:0060467 negative regulation of fertilization(GO:0060467)
0.3 1.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.3 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 0.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 4.8 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.3 0.6 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.3 0.9 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 0.3 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.3 1.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.3 0.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 0.3 GO:0048143 astrocyte activation(GO:0048143)
0.3 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.3 0.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 0.3 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.3 1.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.3 3.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.3 0.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 2.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 0.3 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.3 2.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 1.6 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.3 1.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 0.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 1.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.3 0.8 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 2.3 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.3 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 0.5 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.3 0.3 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.3 0.8 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.3 0.3 GO:0072044 collecting duct development(GO:0072044)
0.3 0.5 GO:0042851 L-alanine metabolic process(GO:0042851)
0.2 0.7 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.2 1.5 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.7 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.7 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 0.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 0.7 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.2 1.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.7 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 0.9 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.2 1.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 3.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 0.2 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.2 0.5 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.2 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 1.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 2.5 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 0.9 GO:0070528 protein kinase C signaling(GO:0070528)
0.2 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.2 1.1 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.4 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.2 0.4 GO:0009233 menaquinone metabolic process(GO:0009233)
0.2 2.2 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 0.2 GO:1902837 amino acid import into cell(GO:1902837)
0.2 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.4 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.2 0.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 0.8 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.2 1.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.4 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.2 2.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.2 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 0.2 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 0.6 GO:0015755 fructose transport(GO:0015755)
0.2 1.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 0.6 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.2 0.4 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.8 GO:0032596 protein transport into membrane raft(GO:0032596)
0.2 1.1 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.2 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 0.4 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2 0.9 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.5 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 1.9 GO:0008347 glial cell migration(GO:0008347)
0.2 0.2 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.2 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 0.2 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.2 5.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.2 0.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.2 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 0.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.2 2.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 0.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 0.8 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.2 0.5 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.2 0.2 GO:0036301 macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.2 0.3 GO:0048865 stem cell fate commitment(GO:0048865)
0.2 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.2 GO:0060789 hair follicle placode formation(GO:0060789)
0.2 0.3 GO:0002666 positive regulation of T cell tolerance induction(GO:0002666)
0.2 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.2 2.0 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 0.5 GO:0050955 thermoception(GO:0050955)
0.2 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 0.8 GO:0042428 serotonin metabolic process(GO:0042428)
0.2 1.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.6 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.9 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.3 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.6 GO:0001963 synaptic transmission, dopaminergic(GO:0001963)
0.1 4.3 GO:0003407 neural retina development(GO:0003407)
0.1 7.0 GO:0099531 presynaptic process involved in chemical synaptic transmission(GO:0099531)
0.1 1.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.1 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.1 GO:0090493 catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.1 0.1 GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.1 0.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:0035627 ceramide transport(GO:0035627)
0.1 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.7 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.1 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.1 0.4 GO:0032610 interleukin-1 alpha production(GO:0032610)
0.1 0.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.4 GO:1904874 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.1 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.1 GO:0021783 preganglionic parasympathetic fiber development(GO:0021783)
0.1 0.5 GO:0071280 cellular response to copper ion(GO:0071280)
0.1 0.4 GO:2000850 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.3 GO:0043576 regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.1 GO:0071639 regulation of interleukin-18 production(GO:0032661) positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.1 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:1903261 regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.1 1.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
0.1 0.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.8 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.7 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.1 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084)
0.1 0.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.1 0.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 1.0 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 1.9 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.1 GO:0072077 renal vesicle morphogenesis(GO:0072077)
0.1 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.1 GO:0014075 response to amine(GO:0014075)
0.1 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.1 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.1 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.2 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.1 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.1 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.1 0.2 GO:0055119 relaxation of cardiac muscle(GO:0055119)
0.1 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.3 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 0.4 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.0 GO:0002339 B cell selection(GO:0002339)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.1 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0015744 succinate transport(GO:0015744)
0.0 0.0 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0 0.1 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0038001 paracrine signaling(GO:0038001)
0.0 0.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0002254 kinin cascade(GO:0002254)
0.0 0.0 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.0 GO:0032276 regulation of gonadotropin secretion(GO:0032276)
0.0 0.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.0 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 13.2 GO:0097451 glial limiting end-foot(GO:0097451)
6.5 19.6 GO:0072534 perineuronal net(GO:0072534)
6.1 60.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
5.1 20.4 GO:0033010 paranodal junction(GO:0033010)
4.6 13.7 GO:0097441 basilar dendrite(GO:0097441)
4.5 22.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
4.5 35.8 GO:0042788 polysomal ribosome(GO:0042788)
4.0 15.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.2 47.8 GO:0031527 filopodium membrane(GO:0031527)
3.1 21.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
2.9 29.1 GO:0035253 ciliary rootlet(GO:0035253)
2.8 5.6 GO:0031258 lamellipodium membrane(GO:0031258)
2.6 18.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.4 19.6 GO:0043083 synaptic cleft(GO:0043083)
2.4 4.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
2.4 9.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
2.3 6.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
2.3 15.8 GO:0071437 invadopodium(GO:0071437)
2.1 8.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.1 2.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
2.0 4.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.9 5.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.8 47.3 GO:0044295 axonal growth cone(GO:0044295)
1.8 9.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.8 7.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.8 5.4 GO:0070552 BRISC complex(GO:0070552)
1.8 17.9 GO:0043194 axon initial segment(GO:0043194)
1.8 10.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.7 44.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.7 5.0 GO:0097427 microtubule bundle(GO:0097427)
1.6 3.3 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
1.6 9.8 GO:1990075 periciliary membrane compartment(GO:1990075)
1.6 34.8 GO:0048786 presynaptic active zone(GO:0048786)
1.6 18.7 GO:0071564 npBAF complex(GO:0071564)
1.5 4.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.5 4.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.5 22.3 GO:0031045 dense core granule(GO:0031045)
1.4 48.8 GO:0042734 presynaptic membrane(GO:0042734)
1.4 18.0 GO:0060077 inhibitory synapse(GO:0060077)
1.3 7.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.3 5.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.3 5.2 GO:0005593 FACIT collagen trimer(GO:0005593)
1.3 7.7 GO:0032584 growth cone membrane(GO:0032584)
1.3 14.1 GO:0042555 MCM complex(GO:0042555)
1.3 8.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.2 9.7 GO:0030673 axolemma(GO:0030673)
1.1 3.4 GO:0000322 storage vacuole(GO:0000322)
1.1 10.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.1 4.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.1 8.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
1.1 5.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.1 1.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
1.0 164.5 GO:0060076 excitatory synapse(GO:0060076)
1.0 6.2 GO:0016012 sarcoglycan complex(GO:0016012)
1.0 9.9 GO:0030061 mitochondrial crista(GO:0030061)
1.0 3.0 GO:0048179 activin receptor complex(GO:0048179)
0.9 4.5 GO:0097433 dense body(GO:0097433)
0.9 2.7 GO:0071797 LUBAC complex(GO:0071797)
0.9 8.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.8 2.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.8 2.4 GO:0005608 laminin-3 complex(GO:0005608)
0.8 7.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.8 2.4 GO:0043511 inhibin complex(GO:0043511)
0.8 7.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.8 5.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 4.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.7 3.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.7 17.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.7 78.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 5.8 GO:0036157 outer dynein arm(GO:0036157)
0.7 37.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.7 4.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.6 7.8 GO:0031512 motile primary cilium(GO:0031512)
0.6 7.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.6 3.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.6 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.6 6.0 GO:0032426 stereocilium tip(GO:0032426)
0.6 3.0 GO:0071547 piP-body(GO:0071547)
0.6 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 1.7 GO:0070939 Dsl1p complex(GO:0070939)
0.6 2.3 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6 0.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.5 1.6 GO:0036396 MIS complex(GO:0036396)
0.5 3.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 3.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 3.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 6.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.5 4.8 GO:0005687 U4 snRNP(GO:0005687)
0.5 7.0 GO:0043205 fibril(GO:0043205)
0.5 7.2 GO:0005614 interstitial matrix(GO:0005614)
0.5 1.8 GO:0097449 astrocyte projection(GO:0097449)
0.4 1.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.4 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 1.2 GO:0000802 transverse filament(GO:0000802)
0.4 1.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 1.2 GO:1990393 3M complex(GO:1990393)
0.4 0.4 GO:0044299 C-fiber(GO:0044299)
0.4 5.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 8.7 GO:0031941 filamentous actin(GO:0031941)
0.3 4.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 1.0 GO:0030891 VCB complex(GO:0030891)
0.3 5.4 GO:0042101 T cell receptor complex(GO:0042101)
0.3 1.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 4.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 3.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 2.3 GO:0031209 SCAR complex(GO:0031209)
0.3 1.0 GO:0032280 symmetric synapse(GO:0032280)
0.3 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.3 6.8 GO:0034451 centriolar satellite(GO:0034451)
0.3 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 3.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 1.1 GO:0070876 SOSS complex(GO:0070876)
0.3 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 3.6 GO:0036038 MKS complex(GO:0036038)
0.3 0.8 GO:0071942 XPC complex(GO:0071942)
0.3 0.8 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.3 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.2 2.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.2 GO:0001940 male pronucleus(GO:0001940)
0.2 0.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.2 1.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.7 GO:0043293 apoptosome(GO:0043293)
0.2 0.9 GO:0071817 MMXD complex(GO:0071817)
0.2 0.9 GO:1990246 uniplex complex(GO:1990246)
0.2 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.0 GO:0090543 Flemming body(GO:0090543)
0.2 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.2 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.2 4.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 2.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 0.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 4.1 GO:0032420 stereocilium(GO:0032420)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 2.6 GO:0070822 Sin3-type complex(GO:0070822)
0.2 1.0 GO:0044292 dendrite terminus(GO:0044292)
0.2 5.9 GO:0030175 filopodium(GO:0030175)
0.2 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 2.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.4 GO:0097440 apical dendrite(GO:0097440)
0.1 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 3.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 5.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.2 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 4.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 3.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.1 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.0 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
7.1 21.4 GO:0070699 type II activin receptor binding(GO:0070699)
7.1 28.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
6.2 31.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
5.8 23.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
5.5 16.4 GO:0097109 neuroligin family protein binding(GO:0097109)
4.9 24.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
4.7 9.4 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
4.4 13.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
4.4 21.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
4.1 28.7 GO:0003680 AT DNA binding(GO:0003680)
3.9 23.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
3.6 7.1 GO:0045503 dynein light chain binding(GO:0045503)
3.4 13.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
3.2 9.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.9 8.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.7 24.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
2.6 5.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
2.6 7.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.6 7.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
2.5 10.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
2.4 7.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.4 9.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.4 4.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
2.2 6.7 GO:0097016 L27 domain binding(GO:0097016)
2.2 6.5 GO:0004995 tachykinin receptor activity(GO:0004995)
2.1 10.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
2.1 8.3 GO:0070878 primary miRNA binding(GO:0070878)
2.0 6.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.0 2.0 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
2.0 6.0 GO:0050816 phosphothreonine binding(GO:0050816)
2.0 39.5 GO:0017075 syntaxin-1 binding(GO:0017075)
2.0 7.9 GO:0032051 clathrin light chain binding(GO:0032051)
1.9 11.7 GO:0048495 Roundabout binding(GO:0048495)
1.9 7.7 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.8 20.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.8 10.9 GO:0008046 axon guidance receptor activity(GO:0008046)
1.8 19.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
1.8 7.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.8 7.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
1.8 9.0 GO:0004385 guanylate kinase activity(GO:0004385)
1.8 14.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
1.8 3.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
1.7 7.0 GO:0008502 melatonin receptor activity(GO:0008502)
1.7 1.7 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
1.7 5.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.7 38.0 GO:0045499 chemorepellent activity(GO:0045499)
1.6 4.9 GO:0017002 activin-activated receptor activity(GO:0017002)
1.6 3.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.6 4.9 GO:0031708 endothelin B receptor binding(GO:0031708)
1.6 4.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.6 7.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.6 6.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
1.6 18.9 GO:0003905 alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
1.5 6.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.5 7.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.5 4.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.4 2.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
1.4 7.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.4 5.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.4 11.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.4 7.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.4 7.0 GO:0004985 opioid receptor activity(GO:0004985)
1.4 5.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.4 5.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.4 6.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.3 12.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.3 2.6 GO:0043199 sulfate binding(GO:0043199)
1.3 2.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.3 8.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.2 3.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.2 3.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
1.2 28.8 GO:0017091 AU-rich element binding(GO:0017091)
1.2 6.0 GO:0042609 CD4 receptor binding(GO:0042609)
1.2 7.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.2 4.8 GO:0038064 collagen receptor activity(GO:0038064)
1.2 3.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.2 3.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.1 3.4 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
1.1 4.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.1 4.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.1 2.2 GO:0098821 BMP receptor activity(GO:0098821)
1.1 2.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.1 5.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.1 7.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
1.1 5.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.1 4.3 GO:0005042 netrin receptor activity(GO:0005042)
1.1 1.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.1 5.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
1.0 21.0 GO:0071837 HMG box domain binding(GO:0071837)
1.0 5.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
1.0 11.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.0 6.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.0 9.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0 3.0 GO:0004359 glutaminase activity(GO:0004359)
1.0 13.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
1.0 2.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.9 2.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.9 2.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.9 3.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.9 10.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.9 16.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.9 2.7 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.9 4.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.9 2.7 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.9 21.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.9 5.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.8 11.7 GO:0016805 dipeptidase activity(GO:0016805)
0.8 5.0 GO:0035473 lipase binding(GO:0035473)
0.8 2.5 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.8 8.8 GO:0044606 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.8 3.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8 4.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.8 28.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.8 3.0 GO:0034618 arginine binding(GO:0034618)
0.8 3.0 GO:0004969 histamine receptor activity(GO:0004969)
0.7 2.2 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.7 3.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.7 6.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 1.4 GO:0035939 microsatellite binding(GO:0035939)
0.7 4.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.7 2.0 GO:0016917 GABA receptor activity(GO:0016917)
0.7 5.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 4.0 GO:0030274 LIM domain binding(GO:0030274)
0.7 5.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.7 6.6 GO:0015026 coreceptor activity(GO:0015026)
0.7 15.7 GO:0034840 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.7 3.9 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.7 5.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.6 1.9 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.6 1.9 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.6 1.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.6 20.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.6 5.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 7.3 GO:0031402 sodium ion binding(GO:0031402)
0.6 1.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.6 2.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.6 4.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.6 6.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 2.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.6 2.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6 2.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.6 1.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.6 3.5 GO:0031628 opioid receptor binding(GO:0031628)
0.6 9.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.6 6.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.6 2.3 GO:0034711 inhibin binding(GO:0034711)
0.6 5.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.6 10.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 15.1 GO:0052770 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.6 2.2 GO:0034056 estrogen response element binding(GO:0034056)
0.6 1.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 2.7 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.5 13.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5 2.7 GO:0017040 ceramidase activity(GO:0017040)
0.5 2.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 15.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.5 3.2 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.5 1.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.5 13.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 1.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5 1.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 7.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.5 1.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.5 11.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 3.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 11.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 1.5 GO:0032357 oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.5 1.5 GO:0001030 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.5 1.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.5 2.5 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.5 1.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 0.9 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.5 2.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.5 2.7 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.5 0.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.4 5.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 1.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.4 7.9 GO:0042056 chemoattractant activity(GO:0042056)
0.4 2.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 1.7 GO:0032564 dATP binding(GO:0032564)
0.4 2.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 4.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 5.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.4 1.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 1.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 2.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.4 2.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 1.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.4 1.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 1.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.4 11.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 1.5 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 1.2 GO:0016015 morphogen activity(GO:0016015)
0.4 3.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 6.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.4 2.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 0.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.4 0.7 GO:0016595 glutamate binding(GO:0016595)
0.4 1.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 3.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 1.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.3 3.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 1.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.3 2.3 GO:0033691 sialic acid binding(GO:0033691)
0.3 4.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 1.0 GO:0018598 mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.3 2.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.3 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 4.4 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 3.4 GO:0001671 ATPase activator activity(GO:0001671)
0.3 3.4 GO:0031404 chloride ion binding(GO:0031404)
0.3 0.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.3 2.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 0.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 6.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 2.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3 1.7 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.3 1.7 GO:0070097 delta-catenin binding(GO:0070097)
0.3 2.7 GO:0051378 serotonin binding(GO:0051378)
0.3 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.3 1.0 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 9.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 4.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.2 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.2 5.2 GO:0004119 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2 0.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.5 GO:0070990 snRNP binding(GO:0070990)
0.2 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 1.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 0.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 1.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.6 GO:0019862 IgA binding(GO:0019862)
0.2 1.1 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity(GO:0004952)
0.2 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 2.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 0.9 GO:0046790 virion binding(GO:0046790)
0.2 9.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.9 GO:0031420 alkali metal ion binding(GO:0031420)
0.2 14.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.5 GO:0089720 caspase binding(GO:0089720)
0.2 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 4.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.6 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0035870 dITP diphosphatase activity(GO:0035870)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.7 GO:0005109 frizzled binding(GO:0005109)
0.1 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 0.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.3 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 16.9 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004083 bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0 0.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.0 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 27.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.3 24.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
1.0 30.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.8 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.8 10.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.6 19.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.6 6.6 PID ALK2 PATHWAY ALK2 signaling events
0.5 1.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.5 11.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 15.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 4.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 5.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.4 10.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 2.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 5.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 6.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 12.2 PID SHP2 PATHWAY SHP2 signaling
0.3 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.3 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 4.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 2.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 2.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 2.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 6.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 29.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
2.4 26.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
2.3 2.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.8 18.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.7 55.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
1.6 18.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.6 11.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.6 4.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.4 30.4 REACTOME MYOGENESIS Genes involved in Myogenesis
1.4 10.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.3 1.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
1.3 9.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.3 15.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.2 19.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.2 17.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.1 3.3 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
1.1 20.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.0 1.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.9 1.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.9 10.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 11.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.9 15.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.8 6.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.8 8.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.8 7.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 8.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.8 5.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.8 11.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.7 15.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 10.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.7 5.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.7 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.7 9.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 7.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.6 23.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 10.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.5 5.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 11.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 6.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 15.8 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.5 3.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.5 6.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.4 2.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.4 3.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.4 5.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 5.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 9.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 3.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 7.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4 4.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 2.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 3.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 4.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.3 2.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 3.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 4.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 6.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 3.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 1.8 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.3 3.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 3.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 7.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 1.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 0.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 6.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.1 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.1 1.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 4.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 0.4 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.5 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.6 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors