Project
ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Klf13

Z-value: 0.96

Motif logo

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Transcription factors associated with Klf13

Gene Symbol Gene ID Gene Info
ENSMUSG00000052040.9 Klf13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Klf13chr7_63937176_6393780611590.384575-0.615.9e-07Click!
Klf13chr7_63938917_639393362110.908055-0.584.2e-06Click!
Klf13chr7_63939410_639399407600.551739-0.584.2e-06Click!
Klf13chr7_63937825_639380189940.442186-0.551.4e-05Click!
Klf13chr7_63941140_6394132323160.209409-0.542.1e-05Click!

Activity of the Klf13 motif across conditions

Conditions sorted by the z-value of the Klf13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_124439906_124440949 11.92 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
441
0.79
chrY_90739614_90740540 11.85 Mid1-ps1
midline 1, pseudogene 1
12980
0.18
chr8_70476397_70477967 5.86 Klhl26
kelch-like 26
214
0.86
chr13_112440041_112440301 4.57 Gm48879
predicted gene, 48879
3575
0.18
chr10_81106448_81106795 4.21 Map2k2
mitogen-activated protein kinase kinase 2
276
0.75
chr9_18473066_18474201 3.53 Zfp558
zinc finger protein 558
74
0.95
chr5_9726061_9726270 3.48 Grm3
glutamate receptor, metabotropic 3
995
0.6
chr10_22191194_22191366 3.45 Raet1e
retinoic acid early transcript 1E
17361
0.1
chr14_120388810_120389107 3.43 Gm26679
predicted gene, 26679
27
0.98
chr12_3236518_3237725 3.42 Rab10os
RAB10, member RAS oncogene family, opposite strand
510
0.74
chr11_42314956_42315148 3.41 Gabra6
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
5997
0.32
chr17_56626470_56627486 3.37 Lonp1
lon peptidase 1, mitochondrial
91
0.92
chr10_22381380_22381531 3.33 Raet1d
retinoic acid early transcript delta
19561
0.12
chr2_57102640_57102858 3.27 Nr4a2
nuclear receptor subfamily 4, group A, member 2
10323
0.2
chr12_108333504_108334768 3.12 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
245
0.91
chr13_60737684_60738259 2.96 Dapk1
death associated protein kinase 1
16025
0.15
chr15_82293240_82293859 2.94 Wbp2nl
WBP2 N-terminal like
5405
0.09
chr17_56664334_56664784 2.91 Ranbp3
RAN binding protein 3
8735
0.11
chr12_102468744_102469733 2.87 Golga5
golgi autoantigen, golgin subfamily a, 5
46
0.97
chr9_119119523_119119674 2.85 Dlec1
deleted in lung and esophageal cancer 1
56
0.96
chr1_5588268_5588565 2.84 Oprk1
opioid receptor, kappa 1
50
0.98
chr4_128884076_128884722 2.84 Trim62
tripartite motif-containing 62
811
0.57
chr8_84990346_84991110 2.83 Hook2
hook microtubule tethering protein 2
86
0.9
chr5_109552541_109552889 2.80 Gm8493
predicted gene 8493
1441
0.33
chr14_14347096_14348750 2.79 Gm48860
predicted gene, 48860
659
0.44
chr4_152886919_152887080 2.72 Gm25779
predicted gene, 25779
126585
0.05
chr5_146384860_146385320 2.68 Wasf3
WAS protein family, member 3
105
0.97
chr5_73599424_73599575 2.58 Lrrc66
leucine rich repeat containing 66
30813
0.13
chr13_95994774_95995004 2.57 Sv2c
synaptic vesicle glycoprotein 2c
4663
0.25
chr1_157798948_157799099 2.34 Gm38256
predicted gene, 38256
141362
0.04
chr7_49496969_49497490 2.26 Gm38059
predicted gene, 38059
27517
0.2
chr8_120509117_120509877 2.24 Gm26971
predicted gene, 26971
11118
0.13
chr7_5019965_5020617 2.22 Zfp865
zinc finger protein 865
85
0.7
chr10_80741710_80742767 2.20 Ap3d1
adaptor-related protein complex 3, delta 1 subunit
26
0.95
chr8_69832079_69833191 2.15 Pbx4
pre B cell leukemia homeobox 4
2
0.96
chr18_35965723_35965937 2.15 Psd2
pleckstrin and Sec7 domain containing 2
725
0.59
chr11_44617130_44617322 2.14 Ebf1
early B cell factor 1
91
0.67
chr6_56568728_56569302 2.12 Pde1c
phosphodiesterase 1C
88
0.97
chr8_70905797_70906132 2.11 Map1s
microtubule-associated protein 1S
18
0.94
chr7_29210966_29212124 2.09 Catsperg1
cation channel sperm associated auxiliary subunit gamma 1
50
0.94
chr7_135863781_135863970 2.08 Gm45241
predicted gene 45241
9427
0.16
chr6_85068662_85069731 2.08 Exoc6b
exocyst complex component 6B
261
0.84
chr3_132855591_132855776 2.07 Gm9403
predicted gene 9403
13287
0.14
chr19_5447521_5447969 2.06 Fosl1
fos-like antigen 1
40
0.9
chr15_37792454_37792630 2.04 Ncald
neurocalcin delta
28
0.98
chr9_114528016_114528485 2.02 C130032M10Rik
RIKEN cDNA C130032M10 gene
12553
0.16
chr2_145674795_145675792 2.00 Rin2
Ras and Rab interactor 2
74
0.98
chr4_154948181_154948553 2.00 Hes5
hes family bHLH transcription factor 5
12556
0.11
chr2_32875948_32876955 1.95 Fam129b
family with sequence similarity 129, member B
337
0.54
chr2_72242138_72242289 1.95 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
81
0.97
chr5_38560766_38562198 1.94 Wdr1
WD repeat domain 1
61
0.97
chr2_26444885_26445708 1.92 Sec16a
SEC16 homolog A, endoplasmic reticulum export factor
80
0.82
chr17_13668639_13669018 1.91 2700054A10Rik
RIKEN cDNA 2700054A10 gene
63
0.97
chr4_120854573_120855281 1.89 Rims3
regulating synaptic membrane exocytosis 3
108
0.95
chr11_67081283_67081678 1.89 Myh3
myosin, heavy polypeptide 3, skeletal muscle, embryonic
3180
0.17
chrX_6778341_6778533 1.88 Dgkk
diacylglycerol kinase kappa
869
0.74
chr16_90400411_90400594 1.84 Hunk
hormonally upregulated Neu-associated kinase
42
0.97
chr7_19118025_19118835 1.83 Gm4969
predicted gene 4969
62
0.92
chr1_172617765_172617949 1.82 Dusp23
dual specificity phosphatase 23
15105
0.12
chr8_46470414_46471778 1.81 Acsl1
acyl-CoA synthetase long-chain family member 1
24
0.97
chr11_70026722_70027238 1.80 Dlg4
discs large MAGUK scaffold protein 4
19
0.93
chr7_64569803_64569954 1.78 Gm44721
predicted gene 44721
40453
0.15
chr8_71727942_71728505 1.74 Fcho1
FCH domain only 1
2507
0.15
chr7_18950998_18951210 1.69 Nova2
NOVA alternative splicing regulator 2
25216
0.07
chr4_119733256_119734302 1.64 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
5
0.98
chr5_41764546_41764740 1.64 Nkx3-2
NK3 homeobox 2
142
0.97
chr5_144357735_144358915 1.64 Dmrt1i
Dmrt1 interacting ncRNA
200
0.51
chr17_11664742_11664947 1.62 Gm10513
predicted gene 10513
67501
0.13
chr8_71628994_71630252 1.60 Mir6769b
microRNA 6769b
1483
0.21
chr8_12873206_12874084 1.59 Mcf2l
mcf.2 transforming sequence-like
161
0.92
chr14_61172444_61173564 1.59 Sacs
sacsin
14
0.98
chr9_91228155_91228326 1.56 Gm29602
predicted gene 29602
12225
0.18
chr14_67308172_67308323 1.55 Gm6878
predicted gene 6878
6464
0.18
chr5_101665294_101665572 1.55 Nkx6-1
NK6 homeobox 1
437
0.83
chr7_78990295_78990597 1.54 Gm26633
predicted gene, 26633
62877
0.08
chr18_84685090_84685924 1.48 Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
120
0.94
chr11_47377484_47377672 1.48 Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
1944
0.5
chr3_88536213_88537501 1.46 Mir1905
microRNA 1905
475
0.58
chr8_112569720_112569921 1.46 Cntnap4
contactin associated protein-like 4
223
0.52
chr2_33543695_33544688 1.45 Gm13530
predicted gene 13530
54409
0.1
chr13_55012325_55012476 1.44 Hk3
hexokinase 3
8504
0.15
chr5_43289896_43290047 1.42 6030400A10Rik
RIKEN cDNA 6030400A10 gene
24814
0.14
chr16_22919964_22920479 1.41 Fetub
fetuin beta
16
0.96
chr3_34642307_34643037 1.39 Gm42692
predicted gene 42692
592
0.6
chr10_93833649_93834340 1.38 Usp44
ubiquitin specific peptidase 44
176
0.93
chr5_139790880_139791640 1.38 Mafk
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
253
0.87
chr19_29325028_29325544 1.36 Insl6
insulin-like 6
70
0.96
chr14_54958021_54958172 1.35 Myh6
myosin, heavy polypeptide 6, cardiac muscle, alpha
189
0.82
chr3_39220025_39220213 1.33 Gm43008
predicted gene 43008
2273
0.42
chr5_142701305_142702538 1.32 Slc29a4
solute carrier family 29 (nucleoside transporters), member 4
180
0.95
chrX_141725754_141725924 1.32 Irs4
insulin receptor substrate 4
576
0.59
chr19_36409278_36410322 1.32 Pcgf5
polycomb group ring finger 5
52
0.97
chr6_91409483_91409682 1.31 Wnt7a
wingless-type MMTV integration site family, member 7A
1781
0.2
chr2_173658978_173659962 1.30 Ppp4r1l-ps
protein phosphatase 4, regulatory subunit 1-like, pseudogene
34
0.8
chr11_120349471_120350657 1.30 0610009L18Rik
RIKEN cDNA 0610009L18 gene
1386
0.18
chr11_117425997_117426148 1.29 Gm11732
predicted gene 11732
106
0.95
chr7_16129395_16130325 1.25 Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
34
0.96
chr7_18963587_18963738 1.24 Nanos2
nanos C2HC-type zinc finger 2
23738
0.07
chr6_22874878_22875647 1.24 Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
240
0.94
chr5_117125754_117126245 1.23 Taok3
TAO kinase 3
302
0.86
chr14_70443361_70444026 1.22 Mir320
microRNA 320
183
0.56
chr8_64946989_64947925 1.22 Tmem192
transmembrane protein 192
203
0.55
chr12_117447218_117447625 1.22 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
69058
0.12
chr16_34004064_34004278 1.22 Gm49594
predicted gene, 49594
3286
0.22
chr3_103102012_103103284 1.18 Dennd2c
DENN/MADD domain containing 2C
12
0.96
chr13_13783865_13785053 1.18 Gng4
guanine nucleotide binding protein (G protein), gamma 4
130
0.96
chr8_71374903_71376449 1.18 Nr2f6
nuclear receptor subfamily 2, group F, member 6
114
0.92
chr13_55474642_55474940 1.16 Mir6944
microRNA 6944
2985
0.11
chr12_108004757_108004945 1.15 Bcl11b
B cell leukemia/lymphoma 11B
1249
0.59
chr8_4677704_4678740 1.15 Gm7461
predicted gene 7461
143
0.62
chr16_77645068_77645328 1.15 Mir125b-2
microRNA 125b-2
1075
0.28
chr15_98951811_98951974 1.14 Gm49450
predicted gene, 49450
1659
0.16
chr4_86748363_86749478 1.14 Dennd4c
DENN/MADD domain containing 4C
365
0.89
chr11_33512825_33513920 1.14 Ranbp17
RAN binding protein 17
258
0.93
chr2_135536302_135536795 1.12 9630028H03Rik
RIKEN cDNA 9630028H03 gene
46748
0.17
chr7_37820786_37820956 1.11 Gm22302
predicted gene, 22302
3476
0.3
chr7_27178071_27179218 1.10 Rab4b
RAB4B, member RAS oncogene family
166
0.84
chr2_152707269_152707927 1.10 H13
histocompatibility 13
15759
0.09
chr13_99444919_99445223 1.09 Map1b
microtubule-associated protein 1B
604
0.74
chr11_35838430_35838735 1.09 Rars
arginyl-tRNA synthetase
4076
0.2
chr1_132559167_132559406 1.09 Cntn2
contactin 2
16030
0.16
chr6_116673486_116674013 1.09 Rassf4
Ras association (RalGDS/AF-6) domain family member 4
22
0.96
chr13_12317316_12317467 1.08 Actn2
actinin alpha 2
23333
0.15
chr14_99045440_99046902 1.07 Mzt1
mitotic spindle organizing protein 1
37
0.51
chr2_73590227_73590410 1.06 Chrna1os
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), opposite strand
5458
0.15
chr13_39001535_39001686 1.06 Slc35b3
solute carrier family 35, member B3
40735
0.15
chr8_71686115_71686959 1.06 Insl3
insulin-like 3
2677
0.12
chr2_135324013_135324227 1.05 Plcb1
phospholipase C, beta 1
74947
0.12
chr6_108828087_108829378 1.05 Edem1
ER degradation enhancer, mannosidase alpha-like 1
58
0.98
chr14_122104619_122105909 1.05 A330035P11Rik
RIKEN cDNA A330035P11 gene
1689
0.23
chr9_7763414_7764605 1.02 Tmem123
transmembrane protein 123
32
0.97
chrX_53643664_53643984 1.02 Rtl8a
retrotransposon Gag like 8A
142
0.92
chr7_27310306_27310823 1.01 Ltbp4
latent transforming growth factor beta binding protein 4
95
0.94
chr7_15954917_15955481 1.01 Nop53
NOP53 ribosome biogenesis factor
9125
0.1
chrX_136957917_136958236 1.00 Tmsb15b2
thymosin beta 15b2
51
0.94
chr9_21797681_21798988 1.00 Kank2
KN motif and ankyrin repeat domains 2
169
0.91
chr17_56424982_56425554 1.00 Ptprs
protein tyrosine phosphatase, receptor type, S
135
0.95
chr16_90220138_90221417 0.97 Sod1
superoxide dismutase 1, soluble
23
0.97
chr4_133055540_133056727 0.97 Ahdc1
AT hook, DNA binding motif, containing 1
10116
0.19
chr6_88841841_88842983 0.97 Abtb1
ankyrin repeat and BTB (POZ) domain containing 1
428
0.42
chr4_63216287_63217000 0.97 Col27a1
collagen, type XXVII, alpha 1
1208
0.45
chr10_87057937_87058923 0.96 1700113H08Rik
RIKEN cDNA 1700113H08 gene
384
0.87
chr9_107714405_107714990 0.96 Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
4222
0.11
chr6_88942621_88943289 0.96 4933427D06Rik
RIKEN cDNA 4933427D06 gene
7728
0.14
chr13_107372004_107372155 0.95 Gm2736
predicted gene 2736
23875
0.19
chr10_81383963_81384933 0.94 Dohh
deoxyhypusine hydroxylase/monooxygenase
11
0.48
chr15_99771905_99772913 0.94 Cers5
ceramide synthase 5
53
0.94
chr2_33130296_33131698 0.93 Garnl3
GTPase activating RANGAP domain-like 3
389
0.84
chr7_27256966_27257266 0.93 Gm15567
predicted gene 15567
816
0.33
chr5_142551306_142551542 0.92 Radil
Ras association and DIL domains
326
0.85
chr4_45018456_45019009 0.92 Polr1e
polymerase (RNA) I polypeptide E
35
0.96
chr17_51790725_51791001 0.91 5830444F18Rik
RIKEN cDNA 5830444F18 gene
2598
0.16
chr13_98354125_98354312 0.90 Foxd1
forkhead box D1
24
0.97
chr7_100932502_100932992 0.89 Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
640
0.64
chr8_83667823_83669013 0.89 Ptger1
prostaglandin E receptor 1 (subtype EP1)
1276
0.29
chr12_102554281_102554622 0.89 Chga
chromogranin A
518
0.75
chr9_107526565_107527044 0.89 Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
147
0.87
chr2_158794072_158795253 0.88 Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
145
0.96
chr5_4623720_4623923 0.88 Fzd1
frizzled class receptor 1
134214
0.04
chr15_76538707_76539267 0.87 Slc52a2
solute carrier protein 52, member 2
23
0.74
chr18_46597470_46598409 0.87 Eif1a
eukaryotic translation initiation factor 1A
75
0.84
chr5_37241363_37242150 0.86 Crmp1
collapsin response mediator protein 1
184
0.95
chr2_160730613_160731328 0.86 Plcg1
phospholipase C, gamma 1
330
0.87
chr7_19010518_19010930 0.86 Irf2bp1
interferon regulatory factor 2 binding protein 1
6680
0.07
chr5_35757643_35758570 0.84 Ablim2
actin-binding LIM protein 2
55
0.97
chr8_3515797_3516665 0.84 Pnpla6
patatin-like phospholipase domain containing 6
430
0.7
chr9_121403105_121403296 0.84 Trak1
trafficking protein, kinesin binding 1
278
0.91
chr9_22050523_22050944 0.84 Elavl3
ELAV like RNA binding protein 3
1277
0.23
chr12_108554100_108554849 0.84 Evl
Ena-vasodilator stimulated phosphoprotein
246
0.85
chr1_21161877_21162028 0.83 Gm2693
predicted gene 2693
17036
0.15
chr10_81167633_81168074 0.82 Pias4
protein inhibitor of activated STAT 4
70
0.92
chr17_56757443_56758083 0.82 Nrtn
neurturin
233
0.86
chr3_20366868_20367395 0.81 Agtr1b
angiotensin II receptor, type 1b
7
0.98
chr16_42339557_42339849 0.81 Gap43
growth associated protein 43
948
0.66
chr15_76987616_76987801 0.80 Gm35933
predicted gene, 35933
316
0.82
chr8_70315603_70316677 0.80 Cers1
ceramide synthase 1
353
0.75
chr13_28946898_28947096 0.80 Sox4
SRY (sex determining region Y)-box 4
6716
0.22
chr16_13818843_13819686 0.80 Ntan1
N-terminal Asn amidase
13
0.5
chr18_49979102_49979704 0.80 Tnfaip8
tumor necrosis factor, alpha-induced protein 8
24
0.98
chr4_9843986_9844421 0.79 Gdf6
growth differentiation factor 6
169
0.96
chr3_104794518_104794903 0.79 Rhoc
ras homolog family member C
2727
0.13
chr10_81464661_81465630 0.79 Gm16105
predicted gene 16105
3986
0.08
chr7_107594304_107595463 0.78 Ppfibp2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
324
0.83
chr4_129440796_129440989 0.78 Zbtb8b
zinc finger and BTB domain containing 8b
39
0.96
chr13_92530160_92531475 0.77 Zfyve16
zinc finger, FYVE domain containing 16
51
0.98
chr10_42477881_42479089 0.77 Afg1l
AFG1 like ATPase
70
0.97
chr1_125560780_125561505 0.77 Slc35f5
solute carrier family 35, member F5
126
0.98
chr8_69822383_69823195 0.76 Lpar2
lysophosphatidic acid receptor 2
205
0.88
chr13_98009130_98009281 0.75 Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
7212
0.28
chr17_56078902_56079299 0.75 Hdgfl2
HDGF like 2
534
0.58
chr4_32656940_32657186 0.74 Mdn1
midasin AAA ATPase 1
56
0.94
chr3_90509125_90509750 0.74 Chtop
chromatin target of PRMT1
13
0.93
chr15_101221336_101221785 0.74 AU021063
expressed sequence AU021063
313
0.78
chr5_138279873_138280191 0.74 Gpc2
glypican 2 (cerebroglycan)
27
0.44
chr16_18686655_18686806 0.74 Rps2-ps7
ribosomal protein S2, pseudogene 7
4514
0.18
chr5_32785233_32785830 0.74 Pisd
phosphatidylserine decarboxylase
50
0.96
chr7_132896569_132896720 0.73 1500002F19Rik
RIKEN cDNA 1500002F19 gene
7957
0.14
chr15_11995897_11996209 0.71 Sub1
SUB1 homolog, transcriptional regulator
5
0.98
chr2_148732332_148732639 0.71 Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
18
0.97
chr15_31338807_31338958 0.71 Ankrd33b
ankyrin repeat domain 33B
13633
0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Klf13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.9 2.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 2.6 GO:2000821 regulation of grooming behavior(GO:2000821)
0.5 2.0 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.5 1.8 GO:0007296 vitellogenesis(GO:0007296)
0.4 1.3 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.4 1.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 0.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 1.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 0.7 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 0.9 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 3.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 1.2 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.3 0.9 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.3 1.8 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 1.3 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.8 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.7 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.2 1.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.2 3.1 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 0.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 1.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.8 GO:0030035 microspike assembly(GO:0030035)
0.2 0.6 GO:0010046 response to mycotoxin(GO:0010046)
0.2 9.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 2.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 0.5 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.2 0.6 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 1.9 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 2.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.4 GO:0070672 response to interleukin-15(GO:0070672)
0.1 1.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.2 GO:0045632 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 3.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 1.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.8 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 0.3 GO:0060066 oviduct development(GO:0060066)
0.1 0.2 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.3 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.3 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
0.1 0.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 1.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.7 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.2 GO:0044838 cell quiescence(GO:0044838)
0.1 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.3 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.1 0.4 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 0.4 GO:0001842 neural fold formation(GO:0001842)
0.1 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.2 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1 0.3 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.1 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 2.0 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.2 GO:1904751 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.0 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.5 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.2 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.1 0.5 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.1 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.1 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.0 0.2 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.4 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0002254 kinin cascade(GO:0002254)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0060068 vagina development(GO:0060068)
0.0 0.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.5 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.2 GO:0051198 negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.0 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.2 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.7 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:2000018 regulation of male gonad development(GO:2000018)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 2.0 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 1.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.3 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.0 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0010878 cholesterol storage(GO:0010878)
0.0 0.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 1.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.0 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988) regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.3 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0035640 exploration behavior(GO:0035640)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.0 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.0 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 0.0 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.7 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.0 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.0 GO:0052200 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.0 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.6 GO:0015844 monoamine transport(GO:0015844)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.0 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.0 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0070695 FHF complex(GO:0070695)
0.5 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.4 1.3 GO:0072534 perineuronal net(GO:0072534)
0.4 2.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 2.3 GO:0036128 CatSper complex(GO:0036128)
0.3 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 0.7 GO:0044393 microspike(GO:0044393)
0.2 1.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 0.6 GO:1990393 3M complex(GO:1990393)
0.2 1.9 GO:0097449 astrocyte projection(GO:0097449)
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 0.6 GO:0071203 WASH complex(GO:0071203)
0.2 0.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.8 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0071547 piP-body(GO:0071547)
0.1 1.9 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 4.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 5.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 2.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 3.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:0032021 NELF complex(GO:0032021)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.6 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0045098 type III intermediate filament(GO:0045098)
0.1 2.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0000802 transverse filament(GO:0000802)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 2.4 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.0 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.2 GO:0044298 cell body membrane(GO:0044298)
0.0 0.2 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 5.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.0 GO:0009279 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.7 2.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.7 3.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.6 1.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) neuroligin family protein binding(GO:0097109)
0.6 2.8 GO:0004985 opioid receptor activity(GO:0004985)
0.4 1.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.4 1.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.4 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 2.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.3 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 3.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.8 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 2.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.1 1.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.8 GO:0031005 filamin binding(GO:0031005)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.3 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.5 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0043829 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 5.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.0 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0031559 oxidosqualene cyclase activity(GO:0031559)
0.0 0.2 GO:0034882 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 3.4 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0019838 growth factor binding(GO:0019838)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0016936 galactoside binding(GO:0016936)
0.0 0.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 2.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 2.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters