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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Lhx4

Z-value: 3.46

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Transcription factors associated with Lhx4

Gene Symbol	Gene ID	Gene Info
Lhx4 Ensembl NCBI MGI UniProt	ENSMUSG00000026468.8	Lhx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Lhx4	chr1_155741976_155742391	156	0.943685	0.73	2.9e-10	Click!
Lhx4	chr1_155742423_155742619	494	0.754902	0.71	9.9e-10	Click!
Lhx4	chr1_155750652_155750824	946	0.488744	0.47	2.6e-04	Click!

Activity of the Lhx4 motif across conditions

Conditions sorted by the z-value of the Lhx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_66869624_66870037	31.24	Gm49940	predicted gene, 49940	7590	0.18
chr3_17789514_17789745	24.55	Mir124-2hg	Mir124-2 host gene (non-protein coding)	292	0.9
chrX_166344291_166344543	24.25	Gpm6b	glycoprotein m6b	275	0.93
chr16_63747767_63748162	22.48	Gm22769	predicted gene, 22769	430	0.91
chr9_122635277_122635496	22.46	Gm47134	predicted gene, 47134	12444	0.13
chr2_53437450_53438022	21.89	Gm13501	predicted gene 13501	39249	0.2
chr19_41164805_41164972	21.21	Tll2	tolloid-like 2	41886	0.16
chr18_45014470_45014883	20.37	Gm31706	predicted gene, 31706	30186	0.16
chr9_9263661_9263812	20.07	Gm16833	predicted gene, 16833	3053	0.29
chr8_31895464_31895660	19.99	Nrg1	neuregulin 1	8976	0.25
chr1_96346717_96347057	19.93	Gm37076	predicted gene, 37076	33645	0.18
chr13_83749857_83750036	19.83	C130071C03Rik	RIKEN cDNA C130071C03 gene	11083	0.12
chr5_20056465_20056826	19.64	Gm23570	predicted gene, 23570	35970	0.2
chr9_101472906_101473083	18.96	Gm5161	predicted pseudogene 5161	23641	0.18
chr2_34106829_34107151	18.67	C230014O12Rik	RIKEN cDNA C230014O12 gene	739	0.69
chr10_84710909_84711119	18.16	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	45048	0.13
chr3_120982893_120983085	17.88	Gm43444	predicted gene 43444	37787	0.16
chr2_106512677_106513062	17.73	Gm14015	predicted gene 14015	10234	0.26
chr3_79475048_79475264	17.20	Fnip2	folliculin interacting protein 2	8951	0.21
chr4_21095762_21096024	17.03	Gm11871	predicted gene 11871	84953	0.1
chr3_78792451_78792970	16.87	Gm18952	predicted gene, 18952	34091	0.19
chr6_61042953_61043250	16.71	Gm43892	predicted gene, 43892	1892	0.33
chr3_16819794_16819956	16.68	Gm26485	predicted gene, 26485	3437	0.4
chr9_66933818_66934187	16.14	Rps27l	ribosomal protein S27-like	12084	0.15
chr2_132427639_132427949	15.92	4921508D12Rik	RIKEN cDNA 4921508D12 gene	3053	0.25
chr8_103314388_103314575	15.57	1600027J07Rik	RIKEN cDNA 1600027J07 gene	33053	0.2
chr13_99444397_99444879	15.44	Map1b	microtubule-associated protein 1B	171	0.95
chr13_99842476_99842627	15.42	Cartpt	CART prepropeptide	58090	0.13
chr9_37114956_37115270	15.23	Gm48716	predicted gene, 48716	3543	0.18
chr15_36966946_36967298	15.01	Gm34590	predicted gene, 34590	28258	0.13
chr2_41498351_41498548	14.98	Lrp1b	low density lipoprotein-related protein 1B	290629	0.01
chr15_85463386_85463550	14.85	7530416G11Rik	RIKEN cDNA 7530416G11 gene	39759	0.14
chr5_4811967_4812118	14.60	Gm44483	predicted gene, 44483	9585	0.12
chr3_3831527_3831694	14.58	Gm2071	predicted gene 2071	2326	0.38
chr6_6603963_6604155	14.53	Sem1	SEM1, 26S proteasome complex subunit	25396	0.18
chr13_78580917_78581111	14.50	Gm48402	predicted gene, 48402	57003	0.14
chr2_151631930_151632148	14.42	Snph	syntaphilin	432	0.78
chr3_18454033_18454237	14.41	Gm30667	predicted gene, 30667	7119	0.22
chr15_95217343_95217494	14.38	1700129L04Rik	RIKEN cDNA 1700129L04 gene	55024	0.17
chr18_37217169_37217576	14.37	Gm10544	predicted gene 10544	38850	0.08
chr13_26657396_26657590	14.35	Gm47883	predicted gene, 47883	23200	0.23
chr17_71976866_71977017	14.18	Gm49924	predicted gene, 49924	49911	0.16
chr1_70442301_70442703	14.13	Gm38272	predicted gene, 38272	129591	0.05
chr11_26806852_26807151	14.09	Gm12070	predicted gene 12070	20368	0.19
chr7_73354299_73354479	14.07	Rgma	repulsive guidance molecule family member A	21120	0.13
chr12_47163286_47163464	13.92	Gm36971	predicted gene, 36971	1667	0.48
chr1_81594178_81594459	13.90	Gm6198	predicted gene 6198	36835	0.2
chr11_111844478_111844667	13.87	Gm11674	predicted gene 11674	43696	0.2
chr18_23036938_23037296	13.82	Nol4	nucleolar protein 4	1539	0.55
chr7_96718538_96719200	13.80	Tenm4	teneurin transmembrane protein 4	59065	0.11
chr7_76789063_76789214	13.78	Gm45210	predicted gene 45210	89421	0.1
chr1_53740102_53740664	13.46	Stk17b	serine/threonine kinase 17b (apoptosis-inducing)	22310	0.18
chr2_57523169_57523407	13.45	Gm13531	predicted gene 13531	97579	0.07
chr2_28797954_28798122	13.38	Gm13385	predicted gene 13385	4469	0.16
chr6_111293807_111293981	13.35	Grm7	glutamate receptor, metabotropic 7	201821	0.03
chr9_92178774_92178925	13.34	Plscr5	phospholipid scramblase family, member 5	14087	0.22
chr1_47163860_47164031	13.33	Gm28826	predicted gene 28826	10484	0.28
chr2_101979368_101979730	13.28	Gm13919	predicted gene 13919	60080	0.11
chr12_50120116_50120285	13.21	Gm40418	predicted gene, 40418	109	0.98
chr7_76393238_76393750	13.18	Agbl1	ATP/GTP binding protein-like 1	17568	0.28
chr10_43106136_43106524	13.17	Gm29245	predicted gene 29245	47886	0.11
chr4_21687885_21688425	13.12	Prdm13	PR domain containing 13	2192	0.29
chr10_26328033_26328184	13.04	L3mbtl3	L3MBTL3 histone methyl-lysine binding protein	11834	0.17
chr2_45356875_45357110	13.02	Gm13479	predicted gene 13479	273	0.94
chr12_51002047_51002408	13.01	Gm40421	predicted gene, 40421	2646	0.28
chr3_34331071_34331263	13.00	Gm38505	predicted gene, 38505	20545	0.21
chr6_54552680_54553127	12.99	Scrn1	secernin 1	1543	0.37
chr2_141955236_141955408	12.96	Fau-ps1	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 1	116533	0.07
chr8_25392912_25393353	12.80	Gm39147	predicted gene, 39147	5888	0.16
chr2_63970238_63970568	12.67	Fign	fidgetin	127585	0.06
chr16_41786838_41787032	12.65	Lsamp	limbic system-associated membrane protein	253516	0.02
chr1_30061154_30061322	12.61	Gm23771	predicted gene, 23771	75304	0.12
chr19_50457584_50457735	12.59	Sorcs1	sortilin-related VPS10 domain containing receptor 1	204981	0.02
chr4_76144419_76144591	12.53	Ptprd	protein tyrosine phosphatase, receptor type, D	10362	0.31
chr2_34107198_34107369	12.50	C230014O12Rik	RIKEN cDNA C230014O12 gene	446	0.84
chr4_111686063_111686242	12.46	Spata6	spermatogenesis associated 6	33832	0.2
chr7_39588456_39589360	12.46	Gm2058	predicted gene 2058	23	0.97
chr5_71976810_71977063	12.45	Gm15617	predicted gene 15617	56552	0.14
chr2_79059440_79059602	12.29	Gm14469	predicted gene 14469	20787	0.2
chr8_29544323_29544526	12.24	Nudc-ps1	nuclear distribution gene C homolog (Aspergillus), pseudogene 1	257443	0.02
chr6_12117902_12118084	12.23	Gm6578	predicted gene 6578	8410	0.23
chr15_37787189_37787357	12.19	Ncald	neurocalcin delta	4727	0.2
chrX_60545622_60545821	12.19	Gm715	predicted gene 715	2298	0.23
chr3_55873681_55873832	12.08	Gm43376	predicted gene 43376	16550	0.19
chr6_112809935_112810331	12.08	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	19326	0.21
chr4_148327377_148327851	12.02	Gm13206	predicted gene 13206	20761	0.14
chr13_83985066_83985623	12.01	Gm4241	predicted gene 4241	2647	0.28
chr14_55052295_55052661	11.99	Zfhx2os	zinc finger homeobox 2, opposite strand	1391	0.2
chr14_35027814_35027992	11.98	Mir346	microRNA 346	133294	0.05
chr5_9703200_9703375	11.96	Grm3	glutamate receptor, metabotropic 3	21883	0.21
chr2_146833312_146833528	11.92	Gm14114	predicted gene 14114	6312	0.24
chr5_111944379_111944557	11.91	Gm42488	predicted gene 42488	233	0.96
chr8_7440241_7440417	11.91	Gm26427	predicted gene, 26427	12001	0.26
chr2_49815790_49816032	11.89	Gm13480	predicted gene 13480	2963	0.3
chr7_96865260_96865776	11.86	Gm25712	predicted gene, 25712	2139	0.28
chr2_51087621_51088075	11.82	Rnd3	Rho family GTPase 3	61246	0.13
chr13_84783651_84783837	11.81	Gm26913	predicted gene, 26913	92803	0.09
chr1_136142237_136142876	11.80	Kif21b	kinesin family member 21B	11102	0.11
chr4_70743499_70743669	11.71	Megf9	multiple EGF-like-domains 9	208589	0.03
chr1_47104196_47104347	11.71	Gm28825	predicted gene 28825	36483	0.19
chr10_29143863_29144732	11.70	Gm9996	predicted gene 9996	103	0.69
chr2_15656666_15656817	11.70	Gm37595	predicted gene, 37595	125628	0.05
chr5_107497898_107498054	11.65	Btbd8	BTB (POZ) domain containing 8	197	0.9
chr5_46201957_46202226	11.64	Gm7931	predicted pseudogene 7931	212253	0.02
chr4_54329031_54329272	11.51	Gm12469	predicted gene 12469	93275	0.09
chr14_55029006_55029605	11.50	Ngdn	neuroguidin, EIF4E binding protein	7883	0.07
chr9_58457758_58457974	11.49	4930461G14Rik	RIKEN cDNA 4930461G14 gene	2744	0.26
chr2_142648071_142648223	11.42	Kif16b	kinesin family member 16B	616	0.81
chr4_41727338_41727565	11.41	Arid3c	AT rich interactive domain 3C (BRIGHT-like)	2835	0.12
chr1_46829988_46830169	11.39	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5821	0.22
chr11_88240584_88240997	11.38	Gm38534	predicted gene, 38534	12578	0.16
chr12_12684520_12684723	11.33	Gm27952	predicted gene, 27952	2003	0.29
chr6_15397521_15397861	11.32	Gm25470	predicted gene, 25470	7290	0.26
chr13_83750227_83750397	11.31	C130071C03Rik	RIKEN cDNA C130071C03 gene	11449	0.12
chr7_51339973_51340169	11.30	Gm45002	predicted gene 45002	54758	0.15
chr8_36195680_36195857	11.28	Gm35520	predicted gene, 35520	7396	0.16
chr12_50191241_50191439	11.27	Gm40418	predicted gene, 40418	71031	0.14
chr13_90136263_90136515	11.26	Gm37727	predicted gene, 37727	20765	0.16
chr12_33225361_33225571	11.22	Atxn7l1os1	ataxin 7-like 1, opposite strand 1	3388	0.28
chr18_27956389_27956743	11.20	Gm33674	predicted gene, 33674	146834	0.05
chr15_30857737_30857940	11.20	9630009A06Rik	RIKEN cDNA 9630009A06 gene	105040	0.07
chr10_70458638_70458831	11.19	Fam13c	family with sequence similarity 13, member C	17808	0.19
chr2_123364591_123364759	11.10	Gm13988	predicted gene 13988	90751	0.1
chr3_79417407_79417581	11.09	Fnip2	folliculin interacting protein 2	48711	0.13
chr6_75253494_75253645	11.05	Gm6210	predicted gene 6210	44490	0.16
chr12_90131976_90132183	11.04	Gm48700	predicted gene, 48700	63980	0.15
chr10_72099225_72099381	11.04	Gm34609	predicted gene, 34609	72321	0.11
chr5_90988282_90988433	11.02	Epgn	epithelial mitogen	39107	0.11
chr12_50190972_50191191	11.01	Gm40418	predicted gene, 40418	70772	0.14
chr5_4651240_4651409	10.98	Fzd1	frizzled class receptor 1	106711	0.06
chr13_52562127_52562509	10.95	Syk	spleen tyrosine kinase	20855	0.22
chr19_28333153_28333358	10.92	Glis3	GLIS family zinc finger 3	7249	0.31
chr18_74956688_74957137	10.86	Lipg	lipase, endothelial	4350	0.11
chr1_61407385_61407544	10.82	9530026F06Rik	RIKEN cDNA 9530026F06 gene	29032	0.14
chr16_79449717_79449914	10.79	Gm37709	predicted gene, 37709	201712	0.03
chr14_64233778_64233929	10.75	9630015K15Rik	RIKEN cDNA 9630015K15 gene	117539	0.05
chr13_59148254_59148405	10.74	Gm34354	predicted gene, 34354	501	0.74
chr2_137939077_137939470	10.72	Gm14062	predicted gene 14062	62442	0.16
chr18_81831298_81831489	10.72	Gm30454	predicted gene, 30454	18623	0.19
chr10_15249538_15249689	10.70	Gm18188	predicted gene, 18188	21565	0.23
chr5_113041463_113042083	10.65	Gm22740	predicted gene, 22740	2371	0.2
chr16_52387159_52387325	10.64	Alcam	activated leukocyte cell adhesion molecule	65223	0.14
chr1_89848298_89848748	10.64	Gm37521	predicted gene, 37521	23042	0.19
chr2_65567228_65567415	10.58	Scn3a	sodium channel, voltage-gated, type III, alpha	171	0.96
chr3_38884380_38884574	10.55	Fat4	FAT atypical cadherin 4	2463	0.32
chrX_42343522_42343895	10.55	Gm14619	predicted gene 14619	3804	0.34
chr13_20609106_20609281	10.52	Gm47721	predicted gene, 47721	36564	0.17
chr1_132921189_132921408	10.50	Gm44300	predicted gene, 44300	2446	0.25
chr10_33624726_33624916	10.49	Clvs2	clavesin 2	52	0.9
chr3_67309812_67309963	10.47	Mlf1	myeloid leukemia factor 1	64210	0.11
chr6_141495522_141495813	10.45	Slco1c1	solute carrier organic anion transporter family, member 1c1	28701	0.2
chr17_11664742_11664947	10.41	Gm10513	predicted gene 10513	67501	0.13
chr3_34504632_34504783	10.40	Gm29135	predicted gene 29135	22500	0.16
chr13_84751597_84751791	10.38	Gm26913	predicted gene, 26913	60753	0.15
chr7_89046968_89047122	10.27	Tmem135	transmembrane protein 135	98452	0.08
chr16_23258903_23259100	10.25	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	10628	0.14
chr3_154817331_154817637	10.22	Gm18589	predicted gene, 18589	22123	0.2
chr1_25180650_25181145	10.22	Adgrb3	adhesion G protein-coupled receptor B3	23826	0.16
chr12_29095750_29095939	10.22	4833405L11Rik	RIKEN cDNA 4833405L11 gene	10893	0.23
chr1_69157499_69157702	10.21	Gm8840	predicted gene 8840	26301	0.2
chr7_123069202_123069353	10.19	Gm45847	predicted gene 45847	37783	0.12
chr2_57916465_57916651	10.17	Gm33594	predicted gene, 33594	69459	0.11
chr9_69844583_69844734	10.15	Gm18745	predicted gene, 18745	51507	0.13
chr13_94376190_94376445	10.15	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	17357	0.17
chr12_33225655_33225815	10.12	Atxn7l1os1	ataxin 7-like 1, opposite strand 1	3119	0.29
chr6_40431416_40431824	10.12	Dennd11	DENN domain containing 11	212	0.91
chr8_102575707_102575858	10.11	Gm45422	predicted gene 45422	41137	0.15
chr3_119949650_119949819	10.11	Gm18384	predicted gene, 18384	18997	0.25
chr4_109762760_109763127	10.05	Gm12808	predicted gene 12808	8126	0.24
chr1_20428787_20428938	10.05	Gm15795	predicted gene 15795	15948	0.17
chr18_25548818_25548982	10.03	Celf4	CUGBP, Elav-like family member 4	47661	0.16
chr3_144318847_144319062	10.03	Gm43447	predicted gene 43447	1260	0.5
chrX_93310384_93310605	10.01	Arx	aristaless related homeobox	23984	0.21
chr6_47175944_47176185	9.98	Cntnap2	contactin associated protein-like 2	68323	0.13
chr4_96968887_96969075	9.97	Gm27521	predicted gene, 27521	51961	0.15
chr5_99062665_99062987	9.95	Prkg2	protein kinase, cGMP-dependent, type II	25475	0.2
chr1_4571274_4571491	9.92	Gm37323	predicted gene, 37323	14870	0.13
chr11_90552646_90552797	9.91	Stxbp4	syntaxin binding protein 4	3811	0.23
chr15_86416205_86416356	9.86	A930001M01Rik	RIKEN cDNA A930001M01 gene	58815	0.14
chr15_10656241_10656392	9.82	Gm10389	predicted gene 10389	55979	0.1
chr2_45225819_45225975	9.78	Gm28643	predicted gene 28643	68972	0.11
chr13_58964694_58965094	9.78	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	93159	0.06
chr3_84221181_84221332	9.77	Trim2	tripartite motif-containing 2	367	0.9
chr2_102337010_102337185	9.77	Gm13868	predicted gene 13868	24890	0.21
chr3_50421873_50422272	9.71	Gm37498	predicted gene, 37498	17789	0.21
chr2_18731674_18731995	9.71	Gm13333	predicted gene 13333	27150	0.12
chr16_62686085_62686411	9.68	Gm9816	predicted pseudogene 9816	30789	0.18
chr12_55536845_55537032	9.66	Aldoart2	aldolase 1 A, retrogene 2	28301	0.14
chr11_93560626_93560915	9.65	Gm11502	predicted gene 11502	89989	0.09
chr17_25561859_25562047	9.60	Gm50026	predicted gene, 50026	740	0.43
chr13_77396463_77396675	9.59	Gm9634	predicted gene 9634	157804	0.04
chr4_54371542_54371700	9.58	Gm12469	predicted gene 12469	135745	0.05
chr10_45009704_45010027	9.57	Gm4795	predicted pseudogene 4795	3755	0.21
chr7_84113348_84113499	9.51	Cemip	cell migration inducing protein, hyaluronan binding	26921	0.14
chr7_96595597_96595770	9.49	Gm15414	predicted gene 15414	33386	0.19
chr2_118995596_118995756	9.49	Gm14089	predicted gene 14089	1392	0.32
chr3_101343856_101344007	9.48	Gm43467	predicted gene 43467	33085	0.11
chr8_54836687_54836851	9.48	n-R5s98	nuclear encoded rRNA 5S 98	29492	0.18
chr3_119948986_119949555	9.47	Gm18384	predicted gene, 18384	19461	0.25
chr7_119363899_119364114	9.46	Gm23321	predicted gene, 23321	57758	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx4

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	23.6	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
4.5	13.5	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
3.5	10.5	GO:0046684	response to pyrethroid(GO:0046684)
2.5	7.6	GO:0032289	central nervous system myelin formation(GO:0032289)
2.2	8.6	GO:0030035	microspike assembly(GO:0030035)
1.9	7.6	GO:0007412	axon target recognition(GO:0007412)
1.9	5.7	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.9	7.5	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.8	5.5	GO:0002121	inter-male aggressive behavior(GO:0002121)
1.7	5.1	GO:2000821	regulation of grooming behavior(GO:2000821)
1.7	5.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
1.7	6.6	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
1.6	4.9	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
1.6	16.3	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.6	4.8	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.6	4.7	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
1.5	4.6	GO:1901529	positive regulation of anion channel activity(GO:1901529)
1.5	4.6	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
1.5	9.1	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
1.4	4.3	GO:1990123	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
1.3	6.6	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
1.3	3.9	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
1.3	3.8	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
1.3	8.8	GO:0042118	endothelial cell activation(GO:0042118)
1.2	9.9	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
1.2	2.5	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.2	3.7	GO:0060178	regulation of exocyst localization(GO:0060178)
1.2	7.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.2	2.3	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.1	3.4	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
1.1	3.2	GO:0031296	B cell costimulation(GO:0031296)
1.1	4.3	GO:1903977	positive regulation of glial cell migration(GO:1903977)
1.0	2.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
1.0	2.9	GO:0099558	maintenance of synapse structure(GO:0099558)
1.0	2.0	GO:0089700	protein kinase D signaling(GO:0089700)
1.0	1.9	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.0	1.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.9	3.7	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.9	6.4	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.9	3.5	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.9	2.6	GO:1990034	calcium ion export from cell(GO:1990034)
0.9	5.2	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.9	5.1	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.8	2.5	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.8	2.5	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.8	3.3	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.8	2.5	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.8	2.5	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.8	2.5	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.8	4.8	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.8	3.9	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.8	2.3	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.8	3.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.8	3.8	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.8	2.3	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.8	3.1	GO:0018343	protein farnesylation(GO:0018343)
0.8	5.4	GO:0016198	axon choice point recognition(GO:0016198)
0.7	3.7	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.7	2.2	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.7	0.7	GO:1901166	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.7	4.3	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.7	1.4	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.7	3.6	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7	4.9	GO:0071625	vocalization behavior(GO:0071625)
0.7	1.4	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.7	3.4	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.7	1.4	GO:0048880	sensory system development(GO:0048880)
0.7	2.0	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.7	1.4	GO:0003358	noradrenergic neuron development(GO:0003358)
0.7	2.7	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.7	1.3	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.7	1.3	GO:0003192	mitral valve formation(GO:0003192)
0.7	2.7	GO:0009957	epidermal cell fate specification(GO:0009957)
0.7	5.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7	5.3	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.6	3.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.6	8.9	GO:0006895	Golgi to endosome transport(GO:0006895)
0.6	0.6	GO:0061642	chemoattraction of axon(GO:0061642)
0.6	9.5	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.6	2.5	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.6	4.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.6	0.6	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.6	3.7	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6	1.8	GO:0072092	ureteric bud invasion(GO:0072092)
0.6	2.4	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.6	3.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.6	3.0	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.6	1.8	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.6	1.8	GO:0006741	NADP biosynthetic process(GO:0006741)
0.6	1.8	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.6	1.8	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.6	0.6	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.6	1.2	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.6	0.6	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.6	2.3	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.6	1.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6	1.7	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.6	1.2	GO:0000101	sulfur amino acid transport(GO:0000101)
0.6	1.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.6	1.1	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.5	1.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5	4.3	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5	1.1	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.5	9.1	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.5	0.5	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.5	2.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5	1.6	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.5	0.5	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.5	5.7	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.5	2.6	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.5	2.0	GO:0014894	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.5	3.9	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.5	1.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.5	1.9	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.5	1.0	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.5	1.4	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.5	1.0	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.5	4.7	GO:0017121	phospholipid scrambling(GO:0017121)
0.5	0.5	GO:0072197	ureter morphogenesis(GO:0072197)
0.5	4.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.5	0.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.5	2.3	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.5	1.4	GO:0097503	sialylation(GO:0097503)
0.5	0.5	GO:0001661	conditioned taste aversion(GO:0001661)
0.5	4.1	GO:0060134	prepulse inhibition(GO:0060134)
0.5	2.3	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.4	3.1	GO:0005513	detection of calcium ion(GO:0005513)
0.4	0.4	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.4	1.3	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.4	2.6	GO:0015884	folic acid transport(GO:0015884)
0.4	2.6	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.4	2.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.4	1.3	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4	1.3	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.4	2.6	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.4	1.3	GO:0001927	exocyst assembly(GO:0001927)
0.4	9.9	GO:0007616	long-term memory(GO:0007616)
0.4	2.6	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.4	0.4	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.4	2.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.4	2.5	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.4	0.8	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.4	3.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.4	1.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.4	1.6	GO:0002051	osteoblast fate commitment(GO:0002051)
0.4	3.6	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.4	2.0	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4	0.8	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.4	1.2	GO:0006562	proline catabolic process(GO:0006562)
0.4	2.4	GO:0099515	actin filament-based transport(GO:0099515)
0.4	2.0	GO:1903887	motile primary cilium assembly(GO:1903887)
0.4	1.9	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.4	2.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.4	3.4	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.4	1.1	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4	1.1	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.4	1.1	GO:0060174	limb bud formation(GO:0060174)
0.4	0.7	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.4	1.1	GO:0015889	cobalamin transport(GO:0015889)
0.4	0.4	GO:0071674	mononuclear cell migration(GO:0071674)
0.4	2.5	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.4	2.9	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.4	1.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.4	1.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.4	1.4	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.4	1.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3	1.0	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.3	0.7	GO:0061743	motor learning(GO:0061743)
0.3	4.4	GO:0003334	keratinocyte development(GO:0003334)
0.3	0.3	GO:0061551	trigeminal ganglion development(GO:0061551)
0.3	1.0	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.3	1.0	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.3	3.0	GO:0006273	lagging strand elongation(GO:0006273)
0.3	1.3	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.3	1.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.3	1.0	GO:0032808	lacrimal gland development(GO:0032808)
0.3	4.9	GO:0016486	peptide hormone processing(GO:0016486)
0.3	1.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3	0.3	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.3	0.6	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.3	1.6	GO:0015808	L-alanine transport(GO:0015808)
0.3	0.3	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.3	4.1	GO:0021871	forebrain regionalization(GO:0021871)
0.3	0.9	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3	1.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.3	1.6	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.3	1.2	GO:0050957	equilibrioception(GO:0050957)
0.3	0.9	GO:0071492	cellular response to UV-A(GO:0071492)
0.3	1.2	GO:0035627	ceramide transport(GO:0035627)
0.3	0.9	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.3	0.9	GO:0071288	cellular response to mercury ion(GO:0071288)
0.3	0.9	GO:0048818	positive regulation of hair follicle maturation(GO:0048818)
0.3	0.9	GO:1903416	response to glycoside(GO:1903416)
0.3	1.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.3	0.6	GO:0021564	vagus nerve development(GO:0021564)
0.3	0.3	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.3	0.3	GO:0043396	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.3	0.6	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	0.8	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.3	4.7	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3	0.6	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3	0.6	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.3	0.8	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	0.5	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.3	0.3	GO:0019086	late viral transcription(GO:0019086)
0.3	0.8	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3	0.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.3	1.3	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.3	2.3	GO:0016082	synaptic vesicle priming(GO:0016082)
0.3	0.5	GO:0003190	atrioventricular valve formation(GO:0003190)
0.3	1.3	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.3	3.8	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.3	0.8	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.3	0.5	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.3	1.8	GO:0006108	malate metabolic process(GO:0006108)
0.2	0.5	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2	0.7	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.2	1.0	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.2	4.0	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	0.9	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2	0.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	1.6	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.2	0.5	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.2	3.0	GO:0010842	retina layer formation(GO:0010842)
0.2	2.7	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2	0.7	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2	2.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	1.8	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2	0.7	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.2	0.5	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2	0.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	1.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	5.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.2	0.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.4	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.2	0.9	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.2	2.0	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.2	0.4	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.2	0.6	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2	0.6	GO:0060618	nipple development(GO:0060618)
0.2	0.2	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2	0.6	GO:0023041	neuronal signal transduction(GO:0023041)
0.2	0.6	GO:0042126	nitrate metabolic process(GO:0042126)
0.2	0.6	GO:1901077	regulation of relaxation of muscle(GO:1901077)
0.2	0.6	GO:0060005	vestibular reflex(GO:0060005)
0.2	2.3	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.2	0.2	GO:0003175	tricuspid valve development(GO:0003175)
0.2	13.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2	0.2	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2	0.6	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	0.4	GO:0072318	clathrin coat disassembly(GO:0072318)
0.2	1.2	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2	1.0	GO:0032196	transposition(GO:0032196)
0.2	1.4	GO:0097066	response to thyroid hormone(GO:0097066)
0.2	0.8	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.2	8.9	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.2	0.4	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.2	0.8	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.2	1.3	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.2	0.2	GO:0097090	presynaptic membrane organization(GO:0097090)
0.2	0.6	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2	0.6	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.2	1.5	GO:0001956	positive regulation of neurotransmitter secretion(GO:0001956)
0.2	0.6	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.2	0.6	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.2	2.0	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.2	0.6	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.5	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.2	0.9	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.2	0.7	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.2	0.4	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2	0.4	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2	0.4	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.2	0.7	GO:0070314	G1 to G0 transition(GO:0070314)
0.2	0.7	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	0.5	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2	0.4	GO:0006624	vacuolar protein processing(GO:0006624)
0.2	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.2	8.0	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2	0.5	GO:0035754	B cell chemotaxis(GO:0035754)
0.2	0.7	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2	0.5	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.2	0.5	GO:0021859	pyramidal neuron differentiation(GO:0021859)
0.2	1.4	GO:0001504	neurotransmitter uptake(GO:0001504)
0.2	2.0	GO:0044458	motile cilium assembly(GO:0044458)
0.2	0.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	0.2	GO:0021586	pons maturation(GO:0021586)
0.2	0.5	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.2	0.5	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.2	0.3	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.2	6.1	GO:0046847	filopodium assembly(GO:0046847)
0.2	0.6	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	1.4	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.2	0.5	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.2	0.5	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.2	0.8	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2	0.3	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2	0.8	GO:0031620	regulation of fever generation(GO:0031620)
0.2	0.6	GO:0033227	dsRNA transport(GO:0033227)
0.2	1.2	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.2	0.2	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.2	0.6	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2	0.8	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.2	0.3	GO:0061055	myotome development(GO:0061055)
0.2	1.4	GO:0071435	potassium ion export(GO:0071435)
0.1	0.4	GO:0021794	thalamus development(GO:0021794)
0.1	0.4	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1	0.1	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	1.3	GO:0035428	hexose transmembrane transport(GO:0035428)
0.1	0.3	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.1	0.1	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.1	0.4	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.1	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.1	0.4	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	0.3	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.6	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1	0.3	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1	1.1	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.3	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1	0.3	GO:0008355	olfactory learning(GO:0008355)
0.1	3.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.4	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.3	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1	0.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	1.9	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.1	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	0.8	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.1	0.3	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.7	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.1	0.5	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.3	GO:0090383	phagosome acidification(GO:0090383)
0.1	3.2	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.1	0.8	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.1	0.3	GO:0090135	actin filament branching(GO:0090135)
0.1	0.3	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	1.0	GO:0097531	mast cell migration(GO:0097531)
0.1	0.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.5	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.4	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.4	GO:0048069	eye pigmentation(GO:0048069)
0.1	0.6	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.9	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.4	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.3	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1	2.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.4	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.5	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1	0.4	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.2	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.4	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.1	0.7	GO:0046697	decidualization(GO:0046697)
0.1	0.6	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1	0.2	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1	0.8	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1	0.4	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.1	0.2	GO:1902896	terminal web assembly(GO:1902896)
0.1	0.2	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.1	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.6	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.1	1.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	1.8	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.8	GO:0003203	endocardial cushion morphogenesis(GO:0003203)
0.1	0.2	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.1	0.2	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1	0.3	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.1	1.3	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.1	0.4	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.1	0.2	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.1	1.9	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.1	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1	2.1	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.1	0.2	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.3	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.1	1.0	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.2	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.8	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.1	0.4	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.1	1.5	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	0.5	GO:0034238	macrophage fusion(GO:0034238)
0.1	0.7	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.2	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.1	0.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.8	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.1	0.4	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.1	0.3	GO:0061042	vascular wound healing(GO:0061042)
0.1	0.3	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.1	0.2	GO:0072683	T cell extravasation(GO:0072683)
0.1	0.5	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.6	GO:0045792	negative regulation of cell size(GO:0045792)
0.1	0.7	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.1	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1	0.1	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.4	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	1.3	GO:0003417	growth plate cartilage development(GO:0003417)
0.1	0.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	0.5	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	1.2	GO:0030497	fatty acid elongation(GO:0030497)
0.1	0.7	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.1	0.7	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	1.0	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.1	0.9	GO:0042220	response to cocaine(GO:0042220)
0.1	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1	0.8	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.4	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.3	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	0.3	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.3	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1	0.5	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.1	0.3	GO:0016095	polyprenol catabolic process(GO:0016095)
0.1	1.9	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	0.3	GO:0071436	sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1	0.5	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.2	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1	0.2	GO:0001555	oocyte growth(GO:0001555)
0.1	0.5	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	0.6	GO:0034650	cortisol metabolic process(GO:0034650)
0.1	0.2	GO:0097195	pilomotor reflex(GO:0097195)
0.1	0.3	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	0.3	GO:0070365	hepatocyte differentiation(GO:0070365)
0.1	0.7	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.3	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.3	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.6	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.1	0.1	GO:0002434	immune complex clearance(GO:0002434)
0.1	0.1	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.8	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.6	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.4	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.1	0.5	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.3	GO:0015074	DNA integration(GO:0015074)
0.1	0.5	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	0.2	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.2	GO:0061511	centriole elongation(GO:0061511)
0.1	0.6	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.1	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.2	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.1	1.3	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	0.5	GO:0015816	glycine transport(GO:0015816)
0.1	0.5	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1	0.2	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.1	0.2	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1	0.1	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.1	0.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.2	GO:0002930	trabecular meshwork development(GO:0002930)
0.1	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	0.5	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.1	GO:0071609	chemokine (C-C motif) ligand 5 production(GO:0071609)
0.1	0.3	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.2	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.1	0.1	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.1	GO:0044359	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205)
0.1	0.2	GO:0071042	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1	0.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.1	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.1	0.5	GO:0001964	startle response(GO:0001964)
0.1	0.3	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.1	0.8	GO:0002063	chondrocyte development(GO:0002063)
0.1	0.4	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	0.2	GO:0060179	male mating behavior(GO:0060179)
0.1	0.1	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.1	GO:1901858	regulation of mitochondrial DNA metabolic process(GO:1901858)
0.1	3.8	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.1	GO:1903358	regulation of Golgi organization(GO:1903358)
0.1	0.4	GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.1	0.1	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.1	0.1	GO:0017085	response to insecticide(GO:0017085)
0.1	0.2	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.7	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.1	0.2	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.1	0.5	GO:0060074	synapse maturation(GO:0060074)
0.1	0.3	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.1	GO:0072198	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	0.2	GO:0046541	saliva secretion(GO:0046541)
0.1	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.1	0.9	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.1	0.1	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
0.1	0.3	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	0.4	GO:0060736	prostate gland growth(GO:0060736)
0.1	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.1	0.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.4	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.2	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.3	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.1	0.1	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.1	0.1	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1	0.1	GO:0071873	response to norepinephrine(GO:0071873)
0.1	0.5	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.2	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.1	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.1	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.1	0.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.1	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1	1.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.2	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	0.2	GO:0008078	mesodermal cell migration(GO:0008078)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.3	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0	0.9	GO:0033198	response to ATP(GO:0033198)
0.0	0.1	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.1	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:0072584	caveolin-mediated endocytosis(GO:0072584)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.2	GO:0060384	innervation(GO:0060384)
0.0	0.3	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.3	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.3	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.3	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.2	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.4	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.4	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.0	0.4	GO:1902572	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0	0.1	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.1	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.0	0.0	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.1	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.1	GO:0044704	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.0	0.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.3	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.3	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.0	0.0	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0034442	regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.0	GO:0090148	membrane fission(GO:0090148)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.0	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.3	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.0	GO:0035826	rubidium ion transport(GO:0035826)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.4	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0003176	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0	0.1	GO:0032607	interferon-alpha production(GO:0032607)
0.0	0.1	GO:0015755	fructose transport(GO:0015755)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.0	GO:0046490	isopentenyl diphosphate metabolic process(GO:0046490)
0.0	0.4	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0	0.4	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:1902563	regulation of neutrophil activation(GO:1902563)
0.0	0.6	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.1	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.0	GO:0035106	operant conditioning(GO:0035106)
0.0	0.0	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.1	GO:0031077	post-embryonic camera-type eye development(GO:0031077)
0.0	0.1	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.0	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0	0.5	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0031652	positive regulation of heat generation(GO:0031652)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.0	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.4	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0	0.1	GO:0042182	ketone catabolic process(GO:0042182)
0.0	0.3	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.2	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.2	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.2	GO:0016045	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0	0.0	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.0	GO:0016115	terpenoid catabolic process(GO:0016115)
0.0	0.1	GO:0097240	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.0	GO:2000969	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.0	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.1	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.3	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.0	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.0	0.0	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093)
0.0	0.0	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.0	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0097242	beta-amyloid clearance(GO:0097242)
0.0	0.0	GO:0042891	antibiotic transport(GO:0042891)
0.0	0.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.0	GO:1900271	regulation of long-term synaptic potentiation(GO:1900271)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.1	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.0	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:0002517	T cell tolerance induction(GO:0002517)
0.0	0.4	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.0	GO:0046959	habituation(GO:0046959)
0.0	0.0	GO:0060437	lung growth(GO:0060437)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
2.0	12.0	GO:0016012	sarcoglycan complex(GO:0016012)
1.6	4.8	GO:0060053	neurofilament cytoskeleton(GO:0060053)
1.6	4.7	GO:0072534	perineuronal net(GO:0072534)
1.1	12.8	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
1.0	8.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
1.0	14.5	GO:0043196	varicosity(GO:0043196)
0.9	6.6	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.9	2.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.8	5.6	GO:0032584	growth cone membrane(GO:0032584)
0.6	4.4	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6	2.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6	5.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6	1.9	GO:0070939	Dsl1p complex(GO:0070939)
0.6	2.3	GO:0019815	B cell receptor complex(GO:0019815)
0.5	4.6	GO:0043194	axon initial segment(GO:0043194)
0.5	3.9	GO:0043083	synaptic cleft(GO:0043083)
0.5	2.4	GO:0097433	dense body(GO:0097433)
0.5	1.4	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4	1.3	GO:0005594	collagen type IX trimer(GO:0005594)
0.4	2.2	GO:0044294	dendritic growth cone(GO:0044294)
0.4	0.8	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.4	22.9	GO:0043198	dendritic shaft(GO:0043198)
0.4	7.1	GO:0060077	inhibitory synapse(GO:0060077)
0.4	1.6	GO:0033010	paranodal junction(GO:0033010)
0.4	3.5	GO:0035253	ciliary rootlet(GO:0035253)
0.4	4.2	GO:0030061	mitochondrial crista(GO:0030061)
0.4	4.6	GO:0030673	axolemma(GO:0030673)
0.4	1.5	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.3	3.4	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.3	1.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3	0.7	GO:0044393	microspike(GO:0044393)
0.3	2.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.3	0.7	GO:0033263	CORVET complex(GO:0033263)
0.3	6.4	GO:0044295	axonal growth cone(GO:0044295)
0.3	0.9	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.3	2.2	GO:0016342	catenin complex(GO:0016342)
0.3	0.9	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.3	13.1	GO:0042734	presynaptic membrane(GO:0042734)
0.3	1.2	GO:1990716	axonemal central apparatus(GO:1990716)
0.3	2.6	GO:0036156	inner dynein arm(GO:0036156)
0.3	1.6	GO:0051286	cell tip(GO:0051286)
0.3	1.6	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.3	0.8	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	1.5	GO:0097449	astrocyte projection(GO:0097449)
0.2	1.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	1.2	GO:0070695	FHF complex(GO:0070695)
0.2	2.1	GO:0005859	muscle myosin complex(GO:0005859)
0.2	1.4	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	7.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	0.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.2	0.7	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2	1.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.2	1.1	GO:0005683	U7 snRNP(GO:0005683)
0.2	2.5	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.2	0.6	GO:0033269	internode region of axon(GO:0033269)
0.2	0.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	1.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	0.8	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2	1.8	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.2	0.2	GO:0031523	Myb complex(GO:0031523)
0.2	1.9	GO:0032433	filopodium tip(GO:0032433)
0.2	0.4	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2	2.6	GO:0000145	exocyst(GO:0000145)
0.2	0.7	GO:0042583	chromaffin granule(GO:0042583)
0.2	0.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	0.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.2	2.8	GO:0042101	T cell receptor complex(GO:0042101)
0.2	2.1	GO:0033655	host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.2	1.5	GO:0000813	ESCRT I complex(GO:0000813)
0.2	0.2	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.2	1.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2	0.3	GO:0097441	basilar dendrite(GO:0097441)
0.2	1.8	GO:0048786	presynaptic active zone(GO:0048786)
0.2	0.5	GO:0042585	germinal vesicle(GO:0042585)
0.2	0.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	2.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	1.7	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	6.3	GO:0005871	kinesin complex(GO:0005871)
0.1	0.3	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	0.9	GO:0005577	fibrinogen complex(GO:0005577)
0.1	1.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.8	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	7.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.4	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.1	GO:0044299	C-fiber(GO:0044299)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.6	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	0.9	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	1.1	GO:0031430	M band(GO:0031430)
0.1	5.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	1.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.8	GO:0001650	fibrillar center(GO:0001650)
0.1	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.9	GO:0097440	apical dendrite(GO:0097440)
0.1	2.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.3	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.6	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	2.6	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.4	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.3	GO:0055087	Ski complex(GO:0055087)
0.1	0.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	1.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	1.5	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	2.0	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.1	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1	0.3	GO:0097470	ribbon synapse(GO:0097470)
0.1	5.5	GO:0043204	perikaryon(GO:0043204)
0.1	0.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	1.0	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.7	GO:0034451	centriolar satellite(GO:0034451)
0.1	2.8	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	0.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.6	GO:0036157	outer dynein arm(GO:0036157)
0.1	1.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	0.1	GO:0030689	Noc complex(GO:0030689)
0.1	0.3	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.2	GO:0043511	inhibin complex(GO:0043511)
0.1	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.3	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.6	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.9	GO:0043205	fibril(GO:0043205)
0.1	0.8	GO:0030914	STAGA complex(GO:0030914)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.5	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.2	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	0.1	GO:1990923	PET complex(GO:1990923)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	4.8	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.6	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.8	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.7	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.9	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	5.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	1.7	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0035363	histone locus body(GO:0035363)
0.0	0.6	GO:0097546	ciliary base(GO:0097546)
0.0	0.9	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.5	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.0	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.3	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.5	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.6	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.5	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.4	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.0	GO:0044308	axonal spine(GO:0044308)
0.0	0.0	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.3	24.9	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
2.5	12.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
2.3	6.8	GO:0070699	type II activin receptor binding(GO:0070699)
2.1	6.3	GO:0030158	protein xylosyltransferase activity(GO:0030158)
1.8	16.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
1.8	5.3	GO:0097109	neuroligin family protein binding(GO:0097109)
1.6	4.9	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
1.6	4.8	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.5	4.4	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
1.4	2.8	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
1.2	8.5	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
1.1	3.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
1.1	4.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.1	4.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.9	2.8	GO:0097108	hedgehog family protein binding(GO:0097108)
0.9	11.8	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9	4.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8	3.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.8	7.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.8	3.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.7	4.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.7	2.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.7	10.0	GO:0031402	sodium ion binding(GO:0031402)
0.7	2.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.6	4.4	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.6	1.9	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.6	7.6	GO:0015172	acidic amino acid transmembrane transporter activity(GO:0015172)
0.6	2.5	GO:0070878	primary miRNA binding(GO:0070878)
0.6	1.2	GO:0045503	dynein light chain binding(GO:0045503)
0.6	3.6	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.6	3.0	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.6	4.8	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6	11.7	GO:0017075	syntaxin-1 binding(GO:0017075)
0.6	5.2	GO:0038191	neuropilin binding(GO:0038191)
0.6	1.7	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.6	1.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.6	1.7	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.6	2.2	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.5	8.7	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.5	3.7	GO:0046790	virion binding(GO:0046790)
0.5	1.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.5	1.6	GO:0016015	morphogen activity(GO:0016015)
0.5	2.5	GO:0030553	cGMP binding(GO:0030553)
0.5	2.4	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5	3.9	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.5	2.9	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.5	1.9	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.5	1.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5	2.3	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5	5.6	GO:0031005	filamin binding(GO:0031005)
0.5	2.8	GO:0048495	Roundabout binding(GO:0048495)
0.4	2.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4	2.6	GO:0032027	myosin light chain binding(GO:0032027)
0.4	2.6	GO:0008517	folic acid transporter activity(GO:0008517)
0.4	3.0	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.4	1.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4	4.8	GO:0030215	semaphorin receptor binding(GO:0030215)
0.4	0.4	GO:0050816	phosphothreonine binding(GO:0050816)
0.4	1.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.4	1.5	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.4	1.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.4	1.5	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.4	4.8	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4	1.8	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.4	1.5	GO:0030911	TPR domain binding(GO:0030911)
0.4	0.7	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.4	7.5	GO:0004120	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.4	8.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.4	1.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.4	1.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4	0.7	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.3	5.1	GO:0016805	dipeptidase activity(GO:0016805)
0.3	2.0	GO:0032184	SUMO polymer binding(GO:0032184)
0.3	1.3	GO:0005042	netrin receptor activity(GO:0005042)
0.3	0.9	GO:0030955	potassium ion binding(GO:0030955)
0.3	4.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.3	1.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.3	5.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3	6.3	GO:0030332	cyclin binding(GO:0030332)
0.3	1.5	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3	0.9	GO:0071209	U7 snRNA binding(GO:0071209)
0.3	4.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.3	2.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.3	0.8	GO:0035514	DNA demethylase activity(GO:0035514)
0.3	1.1	GO:0097001	ceramide binding(GO:0097001)
0.3	2.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.3	0.8	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.3	1.6	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.3	0.8	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.3	0.8	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3	2.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3	0.3	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.3	1.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	0.5	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.2	1.5	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.2	1.7	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2	1.7	GO:0008494	translation activator activity(GO:0008494)
0.2	0.2	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.2	0.7	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.2	0.9	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	0.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.2	1.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.2	2.0	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2	0.9	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	0.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.2	0.9	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.2	0.7	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	0.6	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	1.1	GO:0001515	opioid peptide activity(GO:0001515)
0.2	2.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.2	0.6	GO:0051425	PTB domain binding(GO:0051425)
0.2	2.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.2	1.9	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.2	0.9	GO:0004565	beta-galactosidase activity(GO:0004565)
0.2	2.4	GO:0015026	coreceptor activity(GO:0015026)
0.2	0.5	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.2	1.8	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.2	0.4	GO:0000405	bubble DNA binding(GO:0000405)
0.2	0.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2	0.9	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	0.5	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.2	5.6	GO:0070888	E-box binding(GO:0070888)
0.2	0.5	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2	0.3	GO:0009374	biotin binding(GO:0009374)
0.2	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	0.5	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	1.7	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	1.0	GO:0031419	cobalamin binding(GO:0031419)
0.2	7.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.2	0.3	GO:0030620	U2 snRNA binding(GO:0030620)
0.2	0.6	GO:0031433	telethonin binding(GO:0031433)
0.2	0.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	0.6	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.2	0.3	GO:0031893	vasopressin receptor binding(GO:0031893)
0.2	0.6	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.2	0.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.6	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.6	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.1	1.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.1	1.5	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	0.9	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.6	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.6	GO:0070569	uridylyltransferase activity(GO:0070569)
0.1	0.4	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	1.7	GO:0051018	protein kinase A binding(GO:0051018)
0.1	0.6	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	2.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	3.5	GO:0030507	spectrin binding(GO:0030507)
0.1	3.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.4	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	1.5	GO:0001671	ATPase activator activity(GO:0001671)
0.1	1.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.5	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.8	GO:0035473	lipase binding(GO:0035473)
0.1	1.4	GO:0036218	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.1	0.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.5	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	8.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	0.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	1.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.7	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.9	GO:0003896	DNA primase activity(GO:0003896)
0.1	0.2	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.1	3.1	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.5	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	2.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.7	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.1	1.9	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	2.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.4	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	1.5	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1	0.5	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.1	2.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	4.4	GO:0017022	myosin binding(GO:0017022)
0.1	2.1	GO:0005537	mannose binding(GO:0005537)
0.1	0.5	GO:0035671	enone reductase activity(GO:0035671)
0.1	3.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.2	GO:0019206	nucleoside kinase activity(GO:0019206)
0.1	1.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.1	0.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1	0.7	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.2	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	0.5	GO:0016937	short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.1	0.3	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0019808	polyamine binding(GO:0019808)
0.1	1.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.7	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.1	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.3	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	1.0	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0031493	nucleosomal histone binding(GO:0031493)
0.1	0.2	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.8	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	2.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.2	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.1	0.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	0.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	1.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.3	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1	0.1	GO:0004952	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.1	1.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	0.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.6	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.9	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.1	0.7	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.1	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.1	2.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.3	GO:0099528	G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1	0.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.2	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1	0.6	GO:0042923	neuropeptide binding(GO:0042923)
0.1	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.6	GO:0070636	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	0.3	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.1	0.1	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.1	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.2	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.7	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.5	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0	0.2	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.7	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.7	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0034618	arginine binding(GO:0034618)
0.0	0.0	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.7	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.4	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.9	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.4	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	1.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.5	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.6	GO:0005186	pheromone activity(GO:0005186)
0.0	0.3	GO:0015928	fucosidase activity(GO:0015928)
0.0	0.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.0	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0	0.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0032142	single guanine insertion binding(GO:0032142)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.6	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	1.2	GO:0005267	potassium channel activity(GO:0005267)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.1	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.8	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	2.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	3.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.0	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0022835	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.0	0.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.4	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.3	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	28.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.4	6.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.4	0.8	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	7.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	1.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3	4.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.3	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.3	3.6	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.3	3.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	7.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	3.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	5.8	PID LKB1 PATHWAY	LKB1 signaling events
0.2	2.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	4.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	9.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	3.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	1.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	4.4	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.7	PID INSULIN PATHWAY	Insulin Pathway
0.1	2.0	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	1.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	2.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.3	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	1.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	0.8	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	1.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.4	PID SHP2 PATHWAY	SHP2 signaling
0.1	1.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	0.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	8.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	1.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.7	PID ATR PATHWAY	ATR signaling pathway
0.0	0.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	28.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.9	10.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.8	0.8	REACTOME CELL CELL COMMUNICATION	Genes involved in Cell-Cell communication
0.8	9.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.6	0.6	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.6	0.6	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.5	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	3.7	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.5	1.9	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.4	0.4	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.4	9.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.4	7.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.4	3.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4	8.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.4	4.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	6.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	6.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.3	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.3	2.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.3	4.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3	11.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	13.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	3.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	3.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	4.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	2.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	4.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.2	1.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	3.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	1.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	3.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	2.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	2.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	1.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.2	1.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	2.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2	1.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	0.5	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.2	1.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	4.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	4.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	5.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.7	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	1.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	2.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	0.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	1.6	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.1	0.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	1.9	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	2.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	0.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	4.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.0	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation