Project

ENCODE: ATAC-seq of different tissues during embryonic development

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Msx3

Z-value: 1.04

Motif logo

Transcription factors associated with Msx3

Gene Symbol	Gene ID	Gene Info
Msx3 Ensembl NCBI MGI UniProt	ENSMUSG00000025469.9	Msx3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Msx3	chr7_140059832_140059983	10818	0.085214	0.28	4.1e-02	Click!
Msx3	chr7_140058551_140058709	9541	0.086931	0.25	6.5e-02	Click!
Msx3	chr7_140063115_140063403	14170	0.081242	0.22	1.0e-01	Click!
Msx3	chr7_140060984_140062227	12516	0.083144	0.21	1.3e-01	Click!
Msx3	chr7_140057542_140057693	8528	0.088509	0.21	1.3e-01	Click!

Activity of the Msx3 motif across conditions

Conditions sorted by the z-value of the Msx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_36014873_36015024	4.13	Rps12-ps24	ribosomal protein S12, pseudogene 24	10805	0.2
chr19_59006658_59006882	3.53	Shtn1	shootin 1	31515	0.15
chr16_63806441_63806811	3.41	Epha3	Eph receptor A3	56787	0.15
chr2_21963760_21964435	3.23	Gm13337	predicted gene 13337	103729	0.08
chr7_79525861_79526321	3.19	Mir9-3hg	Mir9-3 host gene	1759	0.18
chr14_59737148_59737645	3.19	Gm19716	predicted gene, 19716	94848	0.07
chr10_84859400_84859551	3.13	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	21327	0.19
chr7_54565545_54565749	2.95	Gm6290	predicted gene 6290	45551	0.19
chr4_71765058_71765568	2.91	Gm11232	predicted gene 11232	7348	0.29
chr17_69686012_69686193	2.88	Gm49895	predicted gene, 49895	89910	0.08
chr7_66120706_66121000	2.87	Gm23042	predicted gene, 23042	1450	0.29
chr8_69122584_69122815	2.79	Lzts1	leucine zipper, putative tumor suppressor 1	18254	0.14
chr7_29071400_29071669	2.70	Gm26604	predicted gene, 26604	69	0.87
chr7_95926221_95926466	2.69	Gm5037	predicted gene 5037	12957	0.31
chr13_21408295_21409056	2.61	Gm50481	predicted gene, 50481	3376	0.09
chr7_83329916_83330067	2.60	Gm44724	predicted gene 44724	26586	0.17
chr5_26176163_26176336	2.60	Gm10220	predicted gene 10220	54828	0.1
chr18_90094273_90094424	2.48	Gm6173	predicted gene 6173	75269	0.11
chr1_14108426_14108817	2.47	Gm37400	predicted gene, 37400	4198	0.31
chr1_41814005_41814309	2.46	Gm29260	predicted gene 29260	32349	0.25
chrX_166344291_166344543	2.45	Gpm6b	glycoprotein m6b	275	0.93
chr1_144177285_144177501	2.41	Rgs13	regulator of G-protein signaling 13	21	0.98
chr11_47069891_47070050	2.41	Gm12175	predicted gene 12175	195557	0.03
chr7_52702834_52703040	2.40	Gm6181	predicted pseudogene 6181	52528	0.18
chr19_59394106_59394400	2.34	Gm33756	predicted gene, 33756	4469	0.19
chr14_24550971_24551440	2.31	Rps24	ribosomal protein S24	60056	0.09
chr1_41605488_41605642	2.29	Gm28634	predicted gene 28634	76022	0.12
chr13_107767262_107767617	2.24	Zswim6	zinc finger SWIM-type containing 6	19157	0.22
chr14_75236389_75236560	2.22	Cpb2	carboxypeptidase B2 (plasma)	5813	0.15
chr6_28132216_28132367	2.20	Grm8	glutamate receptor, metabotropic 8	838	0.68
chr13_78581171_78581365	2.19	Gm48402	predicted gene, 48402	56749	0.14
chr3_69709128_69709981	2.14	Rpl32-ps	ribosomal protein L32, pseudogene	7839	0.17
chr3_40673604_40673797	2.14	Intu	inturned planar cell polarity protein	1079	0.49
chr13_94376190_94376445	2.11	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	17357	0.17
chr14_86749378_86749725	2.10	Diaph3	diaphanous related formin 3	418	0.89
chr6_58895029_58895188	2.09	Herc3	hect domain and RLD 3	5013	0.2
chr1_139346382_139347077	2.07	Crb1	crumbs family member 1, photoreceptor morphogenesis associated	18461	0.17
chr19_38348438_38348761	2.06	Gm50150	predicted gene, 50150	5985	0.16
chr10_87447181_87447667	2.03	Ascl1	achaete-scute family bHLH transcription factor 1	46236	0.13
chr6_97666786_97667241	2.01	Frmd4b	FERM domain containing 4B	49472	0.13
chr2_18731674_18731995	1.99	Gm13333	predicted gene 13333	27150	0.12
chr16_63278367_63278696	1.99	Gm33912	predicted gene, 33912	61089	0.15
chrX_109969856_109970177	1.97	Gm4991	predicted gene 4991	59795	0.17
chr6_103514048_103514248	1.97	Chl1	cell adhesion molecule L1-like	2818	0.24
chr16_63747767_63748162	1.96	Gm22769	predicted gene, 22769	430	0.91
chr12_108326586_108326737	1.94	4930478K11Rik	RIKEN cDNA 4930478K11 gene	1369	0.37
chr2_134003402_134003565	1.93	Gm25258	predicted gene, 25258	419062	0.01
chr12_17486610_17486815	1.92	Gm36752	predicted gene, 36752	50094	0.1
chr4_48287409_48287793	1.90	Invs	inversin	7775	0.2
chr17_89090010_89090391	1.86	Fshr	follicle stimulating hormone receptor	110475	0.07
chr3_117359075_117359226	1.80	Plppr4	phospholipid phosphatase related 4	1098	0.57
chr4_12620803_12621032	1.79	Gm37985	predicted gene, 37985	23529	0.27
chr18_28901621_28901954	1.79	Gm33948	predicted gene, 33948	29562	0.26
chr19_15340555_15340742	1.78	Gm24319	predicted gene, 24319	339356	0.01
chr6_129558999_129559239	1.78	Gm44251	predicted gene, 44251	6671	0.09
chrX_60545622_60545821	1.78	Gm715	predicted gene 715	2298	0.23
chr2_43989878_43990238	1.78	Arhgap15	Rho GTPase activating protein 15	74983	0.12
chr7_54634148_54634330	1.78	Gm6290	predicted gene 6290	23041	0.27
chr12_112541437_112541606	1.76	Tmem179	transmembrane protein 179	24774	0.13
chr8_31895464_31895660	1.74	Nrg1	neuregulin 1	8976	0.25
chr7_144284592_144285016	1.73	Shank2	SH3 and multiple ankyrin repeat domains 2	259	0.95
chr6_99669465_99669765	1.70	Gm20696	predicted gene 20696	2818	0.18
chr6_85165406_85165600	1.69	Spr-ps1	sepiapterin reductase pseudogene 1	10295	0.09
chr1_71614501_71614825	1.68	Fn1	fibronectin 1	5096	0.22
chr4_15167536_15167687	1.68	Gm11845	predicted gene 11845	13219	0.21
chr11_112811149_112811493	1.68	Gm11681	predicted gene 11681	12313	0.18
chr10_30405975_30406418	1.67	Gm4780	predicted gene 4780	32923	0.18
chr8_30732987_30733174	1.66	4933433F19Rik	RIKEN cDNA 4933433F19 gene	164687	0.04
chr3_115632400_115632573	1.66	S1pr1	sphingosine-1-phosphate receptor 1	82586	0.08
chr5_49329145_49329296	1.66	Kcnip4	Kv channel interacting protein 4	43561	0.13
chr19_12143485_12143636	1.66	Olfr76	olfactory receptor 76	20357	0.08
chr1_64409346_64409511	1.64	Gm25748	predicted gene, 25748	13094	0.22
chr16_43502947_43503194	1.62	Zbtb20	zinc finger and BTB domain containing 20	544	0.83
chr18_47301577_47301755	1.61	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	20471	0.21
chr13_90136263_90136515	1.61	Gm37727	predicted gene, 37727	20765	0.16
chr2_118995596_118995756	1.60	Gm14089	predicted gene 14089	1392	0.32
chr13_36518354_36518571	1.59	Fars2	phenylalanine-tRNA synthetase 2 (mitochondrial)	18635	0.16
chr2_40643950_40644201	1.59	Lrp1b	low density lipoprotein-related protein 1B	13313	0.29
chr12_58619814_58620024	1.59	Gm18873	predicted gene, 18873	143987	0.04
chr8_26999303_26999520	1.59	Gm45370	predicted gene 45370	3161	0.13
chr12_7959672_7959823	1.58	Gm48633	predicted gene, 48633	9686	0.19
chr4_111552770_111553060	1.58	Agbl4	ATP/GTP binding protein-like 4	13780	0.27
chr4_85250379_85250530	1.58	Gm12413	predicted gene 12413	4692	0.28
chr16_51521718_51522044	1.57	Gm49608	predicted gene, 49608	104933	0.08
chr12_83342653_83342865	1.56	Dpf3	D4, zinc and double PHD fingers, family 3	8136	0.27
chr4_10973002_10973483	1.56	Rps11-ps3	ribosomal protein S11, pseudogene 3	26634	0.14
chr15_57340728_57340879	1.55	Gm49229	predicted gene, 49229	6946	0.26
chr2_150735739_150736543	1.54	Gm28450	predicted gene 28450	11520	0.12
chr4_20401022_20401283	1.52	Gm11873	predicted gene 11873	10056	0.28
chr10_29143863_29144732	1.52	Gm9996	predicted gene 9996	103	0.69
chr14_15970896_15971065	1.52	Gm47782	predicted gene, 47782	59665	0.11
chr9_119796913_119797064	1.51	Scn11a	sodium channel, voltage-gated, type XI, alpha	26872	0.17
chr18_42739632_42739846	1.51	C030004G16Rik	RIKEN cDNA C030004G16 gene	117280	0.05
chr11_68145549_68145700	1.50	Gm12304	predicted gene 12304	49660	0.11
chr11_107416646_107416819	1.50	Gm11713	predicted gene 11713	6342	0.14
chr13_71149065_71149223	1.50	Mir466f-4	microRNA 466f-4	42055	0.19
chr3_79475048_79475264	1.49	Fnip2	folliculin interacting protein 2	8951	0.21
chr7_49268654_49268859	1.48	Nav2	neuron navigator 2	21911	0.21
chr6_16316657_16316832	1.48	Gm3148	predicted gene 3148	79117	0.1
chr10_57744148_57744671	1.47	Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	16428	0.18
chr6_75253494_75253645	1.47	Gm6210	predicted gene 6210	44490	0.16
chr10_11875757_11876092	1.46	Gm48697	predicted gene, 48697	33993	0.15
chr5_42509326_42509477	1.45	Gm7181	predicted gene 7181	8987	0.33
chr16_71497335_71497513	1.44	Gm22797	predicted gene, 22797	166364	0.04
chr13_64686859_64687010	1.44	Gm47194	predicted gene, 47194	1659	0.29
chr9_61468387_61468621	1.43	Gm47240	predicted gene, 47240	4482	0.22
chr9_32686274_32686469	1.43	Ets1	E26 avian leukemia oncogene 1, 5' domain	9651	0.18
chr14_74360274_74360440	1.41	4933402J15Rik	RIKEN cDNA 4933402J15 gene	4830	0.27
chr17_9579512_9579944	1.41	Gm49807	predicted gene, 49807	30037	0.21
chr1_104768332_104769548	1.39	Cdh20	cadherin 20	411	0.86
chr1_59535160_59535834	1.38	1700122D07Rik	RIKEN cDNA 1700122D07 gene	1732	0.27
chr11_12742259_12742438	1.37	Gm22789	predicted gene, 22789	49535	0.17
chr10_86457747_86457979	1.36	Syn3	synapsin III	34034	0.11
chr9_94838531_94838931	1.36	Mir7656	microRNA 7656	86902	0.09
chr6_53014892_53015071	1.36	Gm26215	predicted gene, 26215	4449	0.24
chr6_5110493_5110850	1.36	Ppp1r9a	protein phosphatase 1, regulatory subunit 9A	12	0.98
chr4_24429061_24429567	1.35	Gm27243	predicted gene 27243	1576	0.43
chr4_96766476_96766652	1.35	Gm12695	predicted gene 12695	18622	0.25
chr1_143742270_143742532	1.34	Glrx2	glutaredoxin 2 (thioltransferase)	1014	0.46
chr4_32049926_32050109	1.34	Gm11927	predicted gene 11927	1721	0.39
chr16_74191732_74191898	1.33	Gm49658	predicted gene, 49658	684	0.72
chr19_56476541_56476761	1.33	Plekhs1	pleckstrin homology domain containing, family S member 1	2250	0.3
chr18_30424160_30424311	1.33	Gm7926	predicted gene 7926	4175	0.2
chr13_99842476_99842627	1.33	Cartpt	CART prepropeptide	58090	0.13
chr12_117053330_117053504	1.32	Gm10421	predicted gene 10421	97798	0.08
chr7_35456565_35456716	1.31	Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	6804	0.13
chrX_61154776_61154939	1.31	Gm24396	predicted gene, 24396	9495	0.16
chr9_48516941_48517277	1.31	Gm23653	predicted gene, 23653	10049	0.15
chr13_18219036_18219211	1.31	Pou6f2	POU domain, class 6, transcription factor 2	32637	0.19
chr14_48709709_48710071	1.31	Gm49153	predicted gene, 49153	5706	0.11
chr7_101237158_101237309	1.31	Gm47324	predicted gene, 47324	985	0.48
chr16_26662914_26663065	1.31	Il1rap	interleukin 1 receptor accessory protein	38833	0.2
chr4_47112581_47112732	1.31	Gm12424	predicted gene 12424	11624	0.15
chr12_92589210_92589401	1.30	Gm18500	predicted gene, 18500	115344	0.07
chr9_20665776_20666021	1.30	Olfm2	olfactomedin 2	7233	0.12
chr12_80760602_80760815	1.29	Ccdc177	coiled-coil domain containing 177	21	0.96
chr3_34331071_34331263	1.28	Gm38505	predicted gene, 38505	20545	0.21
chr2_51087621_51088075	1.27	Rnd3	Rho family GTPase 3	61246	0.13
chr2_118228767_118229033	1.27	Gm22800	predicted gene, 22800	19882	0.14
chr6_54552680_54553127	1.27	Scrn1	secernin 1	1543	0.37
chr11_80335618_80335993	1.27	Rhbdl3	rhomboid like 3	10598	0.18
chr10_26912258_26912409	1.26	Gm48084	predicted gene, 48084	37407	0.15
chr15_83906550_83906701	1.26	Efcab6	EF-hand calcium binding domain 6	12852	0.23
chr16_79449717_79449914	1.26	Gm37709	predicted gene, 37709	201712	0.03
chr12_24584854_24585005	1.26	Grhl1	grainyhead like transcription factor 1	4180	0.21
chrX_169838405_169838582	1.26	Mid1	midline 1	10334	0.25
chr7_54782042_54782216	1.24	Luzp2	leucine zipper protein 2	53369	0.15
chrX_38313231_38313611	1.23	Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	2763	0.23
chr10_72099529_72099696	1.23	Gm34609	predicted gene, 34609	72630	0.1
chr13_72293149_72293314	1.23	Gm4052	predicted gene 4052	56990	0.14
chr13_71507941_71508418	1.23	1700112M02Rik	RIKEN cDNA 1700112M02 gene	20572	0.26
chr14_24526548_24526718	1.23	Rps24	ribosomal protein S24	35484	0.13
chr3_32961625_32961777	1.22	Gm37459	predicted gene, 37459	12975	0.15
chr12_112403937_112404122	1.22	E330035G20Rik	RIKEN cDNA E330035G20 gene	1765	0.3
chr9_9263661_9263812	1.21	Gm16833	predicted gene, 16833	3053	0.29
chr7_121549476_121550040	1.21	4933432K03Rik	RIKEN cDNA 4933432K03 gene	40076	0.15
chr1_53740102_53740664	1.20	Stk17b	serine/threonine kinase 17b (apoptosis-inducing)	22310	0.18
chr17_85319912_85320063	1.19	Rpl31-ps16	ribosomal protein L31, pseudogene 16	178646	0.03
chr4_94987823_94988053	1.19	Gm12694	predicted gene 12694	8735	0.14
chr16_43603831_43604250	1.19	Mir568	microRNA 568	36615	0.15
chr9_67840491_67840890	1.19	Vps13c	vacuolar protein sorting 13C	278	0.91
chr14_78132773_78132953	1.18	Fam216b	family with sequence similarity 216, member B	43856	0.12
chr5_144645511_144645682	1.18	Gm6272	predicted pseudogene 6272	78201	0.08
chr13_44100199_44100380	1.18	Gm33630	predicted gene, 33630	329	0.89
chr12_3930532_3930741	1.18	Gm9088	predicted gene 9088	1404	0.35
chr8_92167277_92167548	1.18	Gm45335	predicted gene 45335	5175	0.21
chr15_26021931_26022113	1.18	Zfp622	zinc finger protein 622	26986	0.18
chr11_82473377_82473528	1.16	Tmem132e	transmembrane protein 132E	35195	0.17
chr19_15803560_15803774	1.16	Gm50348	predicted gene, 50348	609	0.82
chr8_97397267_97397596	1.15	Gm5913	predicted gene 5913	31679	0.2
chr6_103514348_103514781	1.15	Chl1	cell adhesion molecule L1-like	3234	0.22
chr2_123533001_123533494	1.14	Gm13988	predicted gene 13988	259323	0.02
chr8_102575707_102575858	1.14	Gm45422	predicted gene 45422	41137	0.15
chr13_39877388_39877716	1.14	Gm47316	predicted gene, 47316	6829	0.2
chr7_25461846_25462025	1.14	Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	14769	0.1
chr14_66190409_66190717	1.13	Ptk2b	PTK2 protein tyrosine kinase 2 beta	20281	0.18
chr18_39078823_39079010	1.13	Arhgap26	Rho GTPase activating protein 26	20395	0.24
chr12_35008006_35008205	1.13	Prps1l1	phosphoribosyl pyrophosphate synthetase 1-like 1	23344	0.17
chrX_109845151_109845302	1.13	Gm4991	predicted gene 4991	64995	0.15
chr11_21713646_21713804	1.11	Wdpcp	WD repeat containing planar cell polarity effector	18596	0.2
chr7_77824667_77824826	1.11	Gm23239	predicted gene, 23239	85574	0.11
chr9_74925390_74925925	1.11	Fam214a	family with sequence similarity 214, member A	27227	0.15
chr18_78455374_78455574	1.11	4931439C15Rik	RIKEN cDNA 4931439C15 gene	21404	0.24
chr16_60175693_60175844	1.10	Epha6	Eph receptor A6	170047	0.03
chr17_10357464_10357615	1.10	1700110C19Rik	RIKEN cDNA 1700110C19 gene	32937	0.18
chr5_74994963_74995270	1.10	Gm42577	predicted gene 42577	6050	0.16
chr16_66612736_66612887	1.09	1700010K23Rik	RIKEN cDNA 1700010K23 gene	44307	0.21
chr7_96832704_96833057	1.09	Gm44633	predicted gene 44633	14574	0.14
chr10_130281986_130282471	1.09	Neurod4	neurogenic differentiation 4	1988	0.29
chr8_12087483_12087682	1.09	B020031H02Rik	RIKEN cDNA B020031H02 gene	139243	0.04
chr6_127701185_127701975	1.08	Gm43634	predicted gene 43634	57140	0.08
chr3_146319056_146319398	1.08	Gm43334	predicted gene 43334	5193	0.2
chr2_157340114_157340758	1.07	Ghrh	growth hormone releasing hormone	3010	0.22
chr10_110346679_110346830	1.07	Gm47338	predicted gene, 47338	32754	0.21
chr15_78698186_78698356	1.07	Elfn2	leucine rich repeat and fibronectin type III, extracellular 2	12508	0.14
chr18_21758402_21758612	1.07	Klhl14	kelch-like 14	103789	0.07
chr12_17621432_17622097	1.07	Gm48313	predicted gene, 48313	14533	0.17
chr14_103613671_103614004	1.07	Slain1	SLAIN motif family, member 1	36391	0.16
chr3_26933215_26933366	1.06	Gm37659	predicted gene, 37659	79474	0.09
chr1_20428787_20428938	1.06	Gm15795	predicted gene 15795	15948	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.6	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4	1.5	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3	1.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3	0.9	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.2	0.9	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2	1.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2	0.7	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.2	1.0	GO:1903887	motile primary cilium assembly(GO:1903887)
0.2	1.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.2	0.6	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2	0.6	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.2	0.5	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2	2.1	GO:0071625	vocalization behavior(GO:0071625)
0.2	0.8	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.2	0.5	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	0.4	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.3	GO:0060166	olfactory pit development(GO:0060166)
0.1	0.4	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.6	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.4	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.1	0.4	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.4	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1	0.9	GO:0060013	righting reflex(GO:0060013)
0.1	0.3	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1	0.5	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1	0.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.6	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.1	0.9	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.1	0.3	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1	0.3	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.1	0.4	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.1	0.7	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1	0.4	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1	0.4	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	0.4	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.6	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1	0.4	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.3	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.1	0.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.8	GO:0032026	response to magnesium ion(GO:0032026)
0.1	0.4	GO:0030578	PML body organization(GO:0030578)
0.1	0.2	GO:0033058	directional locomotion(GO:0033058)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.4	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.2	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.4	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.3	GO:0021559	trigeminal nerve development(GO:0021559)
0.1	0.2	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.6	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.2	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	1.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.3	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1	0.3	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.4	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.1	0.2	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.1	0.5	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.1	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.1	0.2	GO:0061743	motor learning(GO:0061743)
0.1	0.2	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1	0.2	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1	0.2	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.1	2.2	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1	0.4	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.2	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.3	GO:0014028	notochord formation(GO:0014028)
0.1	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.1	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.2	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.4	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.4	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0002838	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.2	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.2	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.3	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.5	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.5	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0045963	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.2	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.3	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	1.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.3	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.0	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.1	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.3	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.7	GO:0035640	exploration behavior(GO:0035640)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.2	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.2	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.1	GO:1904304	regulation of gastro-intestinal system smooth muscle contraction(GO:1904304)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.1	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	0.2	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.2	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.2	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.5	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.0	0.1	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.1	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.0	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.2	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442)
0.0	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.0	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.1	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.3	GO:0001504	neurotransmitter uptake(GO:0001504)
0.0	0.1	GO:1904587	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.0	0.0	GO:1904833	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.0	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.4	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.3	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.0	0.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.0	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.1	GO:0019374	galactolipid metabolic process(GO:0019374)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.0	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.1	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.0	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.0	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	1.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.2	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.5	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.0	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.0	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:0071435	potassium ion export(GO:0071435)
0.0	0.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.0	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.2	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.0	GO:0001812	positive regulation of type I hypersensitivity(GO:0001812)
0.0	0.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.0	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.0	0.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.2	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.2	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:1901033	positive regulation of response to reactive oxygen species(GO:1901033) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.1	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.0	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0060179	male mating behavior(GO:0060179)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.0	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.0	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.0	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.0	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.1	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.2	GO:0001964	startle response(GO:0001964)
0.0	0.0	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.1	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.0	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.0	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.0	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.0	GO:1904220	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.0	GO:0042891	antibiotic transport(GO:0042891)
0.0	0.1	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.0	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4	1.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.2	1.8	GO:0005883	neurofilament(GO:0005883)
0.2	0.6	GO:0044299	C-fiber(GO:0044299)
0.2	0.5	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.4	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	0.9	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.7	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	0.4	GO:1990357	terminal web(GO:1990357)
0.1	1.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.4	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.6	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	0.5	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	0.3	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.6	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.1	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.1	0.4	GO:0051286	cell tip(GO:0051286)
0.1	0.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	2.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:1990923	PET complex(GO:1990923)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.2	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0072534	perineuronal net(GO:0072534)
0.0	0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.6	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.0	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0032433	filopodium tip(GO:0032433)
0.0	0.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.4	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.0	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.0	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	1.0	GO:0043204	perikaryon(GO:0043204)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.0	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.3	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.4	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.4	1.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.4	1.5	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.3	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.2	0.7	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	1.0	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	0.4	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.1	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	1.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.4	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.4	GO:0045340	mercury ion binding(GO:0045340)
0.1	0.6	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.5	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	0.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	1.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	0.7	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1	0.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.2	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.3	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.4	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.3	GO:0043495	protein anchor(GO:0043495)
0.0	0.5	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.3	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.3	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.6	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.7	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.3	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	1.0	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.6	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	0.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.4	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.3	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	0.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.6	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.7	GO:0017022	myosin binding(GO:0017022)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.1	GO:0018643	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.0	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.2	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.3	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.0	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0043199	sulfate binding(GO:0043199)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.6	PID REELIN PATHWAY	Reelin signaling pathway
0.1	PID SHP2 PATHWAY	SHP2 signaling
0.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
2.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.7	PID CDC42 PATHWAY	CDC42 signaling events
0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants