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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr0b1

Z-value: 0.96

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Transcription factors associated with Nr0b1

Gene Symbol	Gene ID	Gene Info
Nr0b1 Ensembl NCBI MGI UniProt	ENSMUSG00000025056.4	Nr0b1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nr0b1	chrX_86191880_86192031	191	0.953071	0.19	1.6e-01	Click!
Nr0b1	chrX_86192180_86192413	532	0.804936	0.14	3.1e-01	Click!

Activity of the Nr0b1 motif across conditions

Conditions sorted by the z-value of the Nr0b1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_160507758_160508228	1.58	Gm14222	predicted gene 14222	75364	0.09
chr1_158193106_158193497	1.02	Brinp2	bone morphogenic protein/retinoic acid inducible neural-specific 2	103163	0.07
chr8_89659306_89659471	1.00	Gm24212	predicted gene, 24212	7916	0.3
chr9_77461750_77461912	0.96	Lrrc1	leucine rich repeat containing 1	19340	0.18
chr2_24413807_24414039	0.87	Psd4	pleckstrin and Sec7 domain containing 4	8294	0.14
chr5_150772538_150772689	0.86	Pds5b	PDS5 cohesin associated factor B	13249	0.15
chr11_96285319_96285686	0.83	Hoxb7	homeobox B7	1121	0.23
chr4_114843260_114843721	0.82	Gm23230	predicted gene, 23230	1627	0.35
chr14_99641991_99642142	0.80	Gm9298	predicted gene 9298	11400	0.21
chr5_139568114_139568282	0.77	Uncx	UNC homeobox	24300	0.16
chr15_101941988_101942139	0.75	Krt79	keratin 79	1739	0.21
chr3_121588840_121589464	0.75	A730020M07Rik	RIKEN cDNA A730020M07 gene	54215	0.09
chr10_72383409_72383643	0.71	Gm9923	predicted pseudogene 9923	74205	0.12
chr12_44836242_44836433	0.70	Gm15901	predicted gene 15901	86843	0.09
chr16_15253127_15253318	0.69	Gm5404	predicted gene 5404	34378	0.16
chr14_67969837_67970001	0.69	Dock5	dedicator of cytokinesis 5	36477	0.17
chr16_90421246_90421497	0.68	Hunk	hormonally upregulated Neu-associated kinase	20827	0.17
chr19_53437277_53437844	0.68	Mirt1	myocardial infarction associated transcript 1	13931	0.13
chrX_161723359_161723510	0.67	Rai2	retinoic acid induced 2	5807	0.31
chr19_24242240_24242409	0.66	Tjp2	tight junction protein 2	17294	0.17
chr6_22000174_22000336	0.65	Cped1	cadherin-like and PC-esterase domain containing 1	13363	0.24
chr10_55546796_55546947	0.65	Gm46190	predicted gene, 46190	422509	0.01
chr16_27523889_27524083	0.65	Ccdc50	coiled-coil domain containing 50	134018	0.05
chr5_125264626_125264993	0.65	Gm32585	predicted gene, 32585	8006	0.18
chr19_44312061_44312212	0.64	Gm50334	predicted gene, 50334	1636	0.25
chr11_31555146_31555358	0.63	Bod1	biorientation of chromosomes in cell division 1	116475	0.06
chr2_115860910_115861061	0.62	Meis2	Meis homeobox 2	7882	0.31
chr4_55015191_55015349	0.61	Zfp462	zinc finger protein 462	3790	0.31
chr11_88588635_88589214	0.61	Msi2	musashi RNA-binding protein 2	1223	0.57
chr12_69437182_69437482	0.61	5830428M24Rik	RIKEN cDNA 5830428M24 gene	30060	0.12
chr1_13787016_13787370	0.61	Gm5523	predicted pseudogene 5523	314	0.9
chr1_52388259_52388410	0.60	Gm23460	predicted gene, 23460	56210	0.11
chr8_126919247_126919416	0.60	Gm31718	predicted gene, 31718	11116	0.16
chr4_142267317_142267565	0.59	Kazn	kazrin, periplakin interacting protein	28040	0.2
chr6_30460451_30461539	0.59	1700012C14Rik	RIKEN cDNA 1700012C14 gene	10	0.97
chr7_117472179_117472382	0.58	Xylt1	xylosyltransferase 1	3212	0.37
chr1_135788781_135788943	0.58	Tnni1	troponin I, skeletal, slow 1	5797	0.15
chr6_52165009_52165376	0.57	Hoxa2	homeobox A2	361	0.46
chr15_100706437_100706588	0.57	Galnt6os	polypeptide N-acetylgalactosaminyltransferase 6, opposite strand	10732	0.1
chr10_22813643_22813922	0.56	Gm10824	predicted gene 10824	1967	0.28
chr11_60036621_60036772	0.56	Pemt	phosphatidylethanolamine N-methyltransferase	210	0.93
chr2_74749875_74750381	0.56	Haglr	Hoxd antisense growth associated long non-coding RNA	378	0.64
chr17_72022399_72022550	0.55	Gm49924	predicted gene, 49924	95444	0.08
chr9_37460487_37460965	0.55	Gm47945	predicted gene, 47945	17917	0.1
chr19_44677410_44677566	0.53	Gm26644	predicted gene, 26644	17787	0.16
chr5_112565224_112565379	0.53	Sez6l	seizure related 6 homolog like	11567	0.15
chr1_135793419_135794215	0.52	Tnni1	troponin I, skeletal, slow 1	5585	0.15
chr2_74681594_74681905	0.52	Hoxd11	homeobox D11	574	0.41
chr14_100462395_100462546	0.52	6330576A10Rik	RIKEN cDNA 6330576A10 gene	3047	0.27
chr10_80627738_80628084	0.51	Csnk1g2	casein kinase 1, gamma 2	1745	0.16
chr17_85737512_85737677	0.51	CJ186046Rik	Riken cDNA CJ186046 gene	43965	0.14
chr9_21852119_21853097	0.51	Dock6	dedicator of cytokinesis 6	8	0.96
chr14_14803913_14804489	0.50	Nek10	NIMA (never in mitosis gene a)- related kinase 10	786	0.69
chr12_110381177_110381629	0.50	Gm47195	predicted gene, 47195	56018	0.08
chr11_36873121_36873272	0.50	Tenm2	teneurin transmembrane protein 2	70970	0.14
chr2_69585992_69586445	0.49	Lrp2	low density lipoprotein receptor-related protein 2	153	0.96
chr2_145787427_145787839	0.49	Rin2	Ras and Rab interactor 2	1471	0.48
chr4_144941168_144941355	0.48	Gm38074	predicted gene, 38074	17587	0.18
chr4_151367052_151367207	0.48	4930589P08Rik	RIKEN cDNA 4930589P08 gene	9341	0.3
chr13_37966733_37966984	0.48	Rreb1	ras responsive element binding protein 1	19842	0.16
chr18_11239663_11239862	0.48	Gata6	GATA binding protein 6	180715	0.03
chr13_38290533_38290684	0.48	Gm47978	predicted gene, 47978	19999	0.15
chr3_9173889_9174631	0.47	Zbtb10	zinc finger and BTB domain containing 10	76342	0.09
chr5_66000675_66000934	0.47	9130230L23Rik	RIKEN cDNA 9130230L23 gene	529	0.67
chr14_74359714_74359865	0.47	4933402J15Rik	RIKEN cDNA 4933402J15 gene	4262	0.28
chr18_53692268_53692425	0.47	Gm19466	predicted gene, 19466	44195	0.17
chr4_137277102_137277596	0.46	Wnt4	wingless-type MMTV integration site family, member 4	140	0.95
chr2_94273064_94274137	0.46	Mir670hg	MIR670 host gene (non-protein coding)	8682	0.15
chr5_50033873_50034024	0.46	Adgra3	adhesion G protein-coupled receptor A3	19431	0.2
chr8_48843323_48843872	0.45	Gm19744	predicted gene, 19744	68	0.83
chr5_64623783_64623974	0.45	Gm42565	predicted gene 42565	11962	0.12
chr18_35930397_35930931	0.45	Gm50405	predicted gene, 50405	7369	0.12
chr7_24499836_24500017	0.45	Cadm4	cell adhesion molecule 4	35	0.94
chr16_4641918_4642720	0.44	Dnaja3	DnaJ heat shock protein family (Hsp40) member A3	2330	0.17
chr15_61770939_61771188	0.44	D030024E09Rik	RIKEN cDNA D030024E09 gene	3388	0.34
chr6_63257322_63257806	0.44	9330118I20Rik	RIKEN cDNA 9330118I20 gene	61	0.93
chr19_36789834_36790425	0.44	Gm50112	predicted gene, 50112	28519	0.16
chr2_33605150_33605418	0.44	Gm38011	predicted gene, 38011	9114	0.17
chrX_99172415_99172601	0.44	Efnb1	ephrin B1	34377	0.2
chr12_102722552_102722730	0.44	Gm21971	predicted gene 21971	4681	0.1
chr18_77564959_77566098	0.44	Rnf165	ring finger protein 165	367	0.89
chr11_118534751_118534902	0.43	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	27473	0.15
chr18_61653267_61653989	0.43	Mir143	microRNA 143	4370	0.12
chr11_96333479_96333781	0.43	Hoxb3	homeobox B3	5568	0.08
chr3_9347475_9347898	0.42	C030034L19Rik	RIKEN cDNA C030034L19 gene	55378	0.14
chr2_168440902_168441073	0.42	Gm14234	predicted gene 14234	22413	0.2
chr16_91056426_91056805	0.41	4931406G06Rik	RIKEN cDNA 4931406G06 gene	11959	0.1
chr4_139967588_139967819	0.41	Mir2139	microRNA 2139	83	0.79
chr10_77165545_77165750	0.41	Col18a1	collagen, type XVIII, alpha 1	901	0.59
chr3_63899936_63900620	0.40	Plch1	phospholipase C, eta 1	806	0.55
chr17_65642831_65642982	0.40	Txndc2	thioredoxin domain containing 2 (spermatozoa)	738	0.63
chr11_121510660_121510811	0.40	Zfp750	zinc finger protein 750	8598	0.17
chr16_26049836_26049987	0.40	AU015336	expressed sequence AU015336	8643	0.25
chr18_59062665_59063371	0.40	Minar2	membrane integral NOTCH2 associated receptor 2	507	0.87
chr4_22393242_22393393	0.40	Gm24607	predicted gene, 24607	3253	0.24
chr11_98709033_98709497	0.40	Med24	mediator complex subunit 24	1262	0.24
chrX_48193816_48193967	0.40	Zdhhc9	zinc finger, DHHC domain containing 9	14437	0.16
chr3_90537217_90537409	0.40	S100a16	S100 calcium binding protein A16	2	0.94
chr5_141380812_141381047	0.40	Gm16035	predicted gene 16035	3	0.98
chr15_99096778_99097375	0.40	Dnajc22	DnaJ heat shock protein family (Hsp40) member C22	2336	0.14
chr8_34392545_34392896	0.39	Gm33831	predicted gene, 33831	6892	0.17
chr14_65266098_65266731	0.39	Fbxo16	F-box protein 16	204	0.93
chr5_36945032_36945744	0.39	Ppp2r2c	protein phosphatase 2, regulatory subunit B, gamma	5958	0.18
chr4_6222763_6222917	0.39	Ubxn2b	UBX domain protein 2B	31742	0.16
chr18_77487881_77488049	0.39	Rnf165	ring finger protein 165	17153	0.19
chr5_74315928_74316086	0.39	Gm15981	predicted gene 15981	1027	0.5
chr14_60913290_60913441	0.39	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	62520	0.12
chr1_185969251_185969582	0.39	Gm9722	predicted gene 9722	90531	0.08
chr2_137098401_137098624	0.38	Jag1	jagged 1	12563	0.27
chr14_28058554_28058730	0.38	Erc2	ELKS/RAB6-interacting/CAST family member 2	12214	0.3
chr4_28298862_28299161	0.38	Gm11907	predicted gene 11907	54772	0.15
chr12_105512184_105512567	0.38	AU015791	expressed sequence AU015791	1105	0.48
chr17_15993469_15994300	0.38	Eif3s6-ps3	eukaryotic translation initiation factor 3, subunit 6, pseudogene 3	148604	0.04
chr8_54780454_54780686	0.38	Wdr17	WD repeat domain 17	56066	0.12
chr2_83739879_83740030	0.37	Dnmt3l-ps1	DNA methyltransferase 3-like, pseudogene 1	5782	0.16
chr7_144762962_144763113	0.37	Gm10152	predicted gene 10152	102	0.94
chr5_64298395_64298660	0.37	Tbc1d1	TBC1 domain family, member 1	3	0.97
chr16_24282164_24282718	0.37	AC169509.1	BMP2 inducible kinase (Bmp2k) pseudogene	7395	0.21
chr16_40891355_40891873	0.37	Gm26381	predicted gene, 26381	326131	0.01
chr4_123239382_123240167	0.37	Heyl	hairy/enhancer-of-split related with YRPW motif-like	17	0.96
chr9_31688233_31688384	0.37	Gm47436	predicted gene, 47436	10282	0.21
chr1_128471971_128472514	0.36	Gm23902	predicted gene, 23902	17798	0.13
chr5_136467645_136467981	0.36	Gm38082	predicted gene, 38082	68664	0.09
chr14_54577785_54578159	0.36	Ajuba	ajuba LIM protein	414	0.66
chr1_85934173_85934375	0.36	Gm28884	predicted gene 28884	3058	0.16
chr7_70331281_70331985	0.36	Gm29683	predicted gene, 29683	6189	0.14
chr19_37026547_37026698	0.36	Btaf1	B-TFIID TATA-box binding protein associated factor 1	65307	0.1
chr3_104352851_104353013	0.36	Gm5546	predicted gene 5546	13681	0.16
chr10_78787742_78788305	0.36	Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	7321	0.14
chr2_18031988_18032457	0.36	Gm13330	predicted gene 13330	311	0.81
chr4_134098701_134098852	0.35	Cd52	CD52 antigen	3694	0.12
chr7_68264707_68264858	0.35	Pgpep1l	pyroglutamyl-peptidase I-like	549	0.7
chr2_4717789_4718511	0.35	Bend7	BEN domain containing 7	5	0.98
chr1_12692125_12692347	0.35	Sulf1	sulfatase 1	41	0.98
chr9_96786211_96786362	0.35	C430002N11Rik	RIKEN cDNA C430002N11 gene	20685	0.13
chr10_117625499_117625695	0.35	Cpm	carboxypeptidase M	3903	0.16
chr11_59012500_59012651	0.35	Gm10435	predicted gene 10435	9665	0.09
chr4_133084081_133084901	0.35	Ahdc1	AT hook, DNA binding motif, containing 1	18242	0.17
chr6_87937321_87937742	0.35	Hmces	5-hydroxymethylcytosine (hmC) binding, ES cell specific	4538	0.1
chr6_90661294_90661504	0.35	Iqsec1	IQ motif and Sec7 domain 1	889	0.52
chr3_123690346_123691118	0.35	Ndst3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3	121	0.96
chr5_52975553_52975747	0.34	Gm30301	predicted gene, 30301	6387	0.16
chr2_178610359_178610510	0.34	Cdh26	cadherin-like 26	149804	0.04
chr7_70330793_70331031	0.34	Gm29683	predicted gene, 29683	6910	0.14
chr3_88563593_88563744	0.34	Ubqln4	ubiquilin 4	239	0.81
chr5_135488643_135489936	0.34	Hip1	huntingtin interacting protein 1	31	0.97
chr13_73263734_73263998	0.34	Irx4	Iroquois homeobox 4	3369	0.2
chr6_117552214_117552390	0.34	Gm9946	predicted gene 9946	7395	0.22
chr8_105461526_105461678	0.34	Tppp3	tubulin polymerization-promoting protein family member 3	7060	0.1
chr8_22475514_22475708	0.34	Slc20a2	solute carrier family 20, member 2	1177	0.29
chr3_108225914_108226065	0.33	Sypl2	synaptophysin-like 2	654	0.36
chr7_142542689_142542861	0.33	Mrpl23	mitochondrial ribosomal protein L23	6671	0.11
chr11_101269713_101269991	0.33	Gm11615	predicted gene 11615	3549	0.08
chr17_25374164_25374315	0.33	Tpsg1	tryptase gamma 1	1230	0.27
chr3_65857996_65858503	0.33	Gm37131	predicted gene, 37131	6580	0.17
chr15_4079762_4080117	0.33	Gm15632	predicted gene 15632	7907	0.19
chr1_34011806_34012218	0.33	Dst	dystonin	187	0.93
chr8_88604116_88604818	0.33	Nkd1	naked cuticle 1	21662	0.15
chr3_93597159_93597878	0.33	Gm5541	predicted gene 5541	32234	0.09
chr4_110351157_110352032	0.33	Elavl4	ELAV like RNA binding protein 4	315	0.93
chr6_71149597_71149803	0.32	Thnsl2	threonine synthase-like 2 (bacterial)	5261	0.14
chr14_105483037_105483250	0.32	4930449E01Rik	RIKEN cDNA 4930449E01 gene	15645	0.19
chr7_30291145_30292058	0.32	Clip3	CAP-GLY domain containing linker protein 3	127	0.89
chrX_142698232_142698408	0.32	Tmem164	transmembrane protein 164	15432	0.19
chr2_105127208_105127384	0.32	Wt1	Wilms tumor 1 homolog	86	0.93
chr8_122430799_122430950	0.32	Cyba	cytochrome b-245, alpha polypeptide	2031	0.15
chr7_39655676_39656025	0.32	Gm2021	predicted gene 2021	7159	0.17
chr15_79741326_79742933	0.32	Sun2	Sad1 and UNC84 domain containing 2	14	0.89
chr4_149813946_149814101	0.32	Gm13064	predicted gene 13064	1199	0.3
chr10_103367406_103367811	0.32	Slc6a15	solute carrier family 6 (neurotransmitter transporter), member 15	175	0.96
chr18_65739933_65740110	0.31	Oacyl	O-acyltransferase like	8993	0.15
chr19_11818404_11818833	0.31	Stx3	syntaxin 3	103	0.94
chr2_33919949_33920348	0.31	Gm13403	predicted gene 13403	21965	0.18
chrX_169997358_169997792	0.31	Gm15247	predicted gene 15247	10636	0.15
chr2_50694913_50695121	0.31	Gm13484	predicted gene 13484	36950	0.21
chr11_103355388_103355579	0.31	Arhgap27os2	Rho GTPase activating protein 27, opposite strand 2	218	0.83
chr11_100395108_100395582	0.31	Jup	junction plakoglobin	2404	0.12
chr6_108448067_108448376	0.31	Itpr1	inositol 1,4,5-trisphosphate receptor 1	10482	0.19
chr19_52647066_52647670	0.30	AA387883	expressed sequence AA387883	275813	0.01
chr15_25940377_25941010	0.30	Retreg1	reticulophagy regulator 1	9	0.98
chr9_69712806_69712957	0.30	B230323A14Rik	RIKEN cDNA B230323A14 gene	45859	0.14
chr4_101585127_101585353	0.30	Dnajc6	DnaJ heat shock protein family (Hsp40) member C6	34646	0.17
chr7_70361365_70362023	0.30	Nr2f2	nuclear receptor subfamily 2, group F, member 2	1101	0.37
chr16_90619588_90619750	0.30	Gm23406	predicted gene, 23406	17173	0.14
chr16_93615032_93615511	0.30	Cbr1	carbonyl reductase 1	7382	0.12
chr3_132084022_132084369	0.30	Dkk2	dickkopf WNT signaling pathway inhibitor 2	1097	0.5
chr16_43800505_43800843	0.30	Gm25996	predicted gene, 25996	3257	0.21
chr14_47766475_47766644	0.30	4930538L07Rik	RIKEN cDNA 4930538L07 gene	9061	0.15
chr18_46311791_46312285	0.30	Ccdc112	coiled-coil domain containing 112	110	0.96
chr16_44559074_44559234	0.30	Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	257	0.86
chr2_35508565_35508933	0.30	Gm35202	predicted gene, 35202	5218	0.15
chr5_63649286_63649509	0.30	Nwd2	NACHT and WD repeat domain containing 2	64	0.95
chr17_45805881_45806117	0.30	Gm35692	predicted gene, 35692	16324	0.15
chr6_52191848_52192469	0.30	Hoxa4	homeobox A4	405	0.56
chr5_122950982_122952145	0.29	Kdm2b	lysine (K)-specific demethylase 2B	427	0.77
chr14_75540763_75541352	0.29	Cby2	chibby family member 2	50892	0.13
chr2_153436314_153437355	0.29	Nol4l	nucleolar protein 4-like	7645	0.17
chr4_154480275_154480463	0.29	Prdm16	PR domain containing 16	48396	0.13
chr14_76533528_76533831	0.29	E130202H07Rik	RIKEN cDNA E130202H07 gene	7063	0.2
chr16_13357793_13358521	0.29	Mrtfb	myocardin related transcription factor B	264	0.93

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr0b1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	GO:0072039	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.2	0.5	GO:0072162	metanephric mesenchymal cell differentiation(GO:0072162)
0.2	0.7	GO:1900211	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.1	0.4	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.5	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.5	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.1	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.3	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.3	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.1	0.3	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.1	0.3	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.3	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.3	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.2	GO:0002930	trabecular meshwork development(GO:0002930)
0.1	0.2	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.2	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	0.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.2	GO:0000101	sulfur amino acid transport(GO:0000101)
0.1	0.1	GO:1903059	regulation of protein lipidation(GO:1903059)
0.1	0.2	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.3	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.2	GO:0048382	mesendoderm development(GO:0048382)
0.1	0.3	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1	0.1	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
0.1	0.2	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.1	0.3	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1	0.1	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.1	0.2	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.3	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.1	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.1	0.2	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1	0.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.2	GO:0034436	glycoprotein transport(GO:0034436)
0.1	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1	0.2	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.1	0.2	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.1	0.2	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.2	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.0	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.2	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.2	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.2	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.1	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.6	GO:0043586	tongue development(GO:0043586)
0.0	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.2	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.5	GO:0045056	transcytosis(GO:0045056)
0.0	0.2	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.0	0.2	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.0	0.1	GO:0061642	chemoattraction of axon(GO:0061642)
0.0	0.1	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	1.0	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0050975	sensory perception of touch(GO:0050975)
0.0	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0060066	oviduct development(GO:0060066)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.5	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.6	GO:1902668	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.1	GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038)
0.0	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.3	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.2	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.4	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.1	GO:0043308	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0021586	pons maturation(GO:0021586)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.1	GO:0071679	commissural neuron axon guidance(GO:0071679)
0.0	0.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	1.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:2000589	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) regulation of metanephric mesenchymal cell migration(GO:2000589)
0.0	0.1	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.1	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.3	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.2	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.0	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.0	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.0	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.2	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.0	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0	0.0	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	0.0	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.2	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.1	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0061205	paramesonephric duct development(GO:0061205)
0.0	0.0	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.0	0.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.3	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0	0.0	GO:0009946	proximal/distal axis specification(GO:0009946)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0097503	sialylation(GO:0097503)
0.0	0.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.2	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.1	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.3	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.0	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.0	GO:1903984	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.0	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.2	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.2	GO:0042711	maternal behavior(GO:0042711)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.0	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.0	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.1	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.0	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.3	GO:1903861	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.0	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.0	GO:0010182	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0	0.0	GO:0021747	cochlear nucleus development(GO:0021747)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.2	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.0	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.3	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.0	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:1904752	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670)
0.0	0.3	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.2	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.0	0.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.2	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0	0.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.0	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.1	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.0	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.2	GO:0097513	myosin II filament(GO:0097513)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.4	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:1990357	terminal web(GO:1990357)
0.0	0.5	GO:0043194	axon initial segment(GO:0043194)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.3	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0072534	perineuronal net(GO:0072534)
0.0	0.4	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0060091	kinocilium(GO:0060091)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	1.0	GO:0031526	brush border membrane(GO:0031526)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0008305	integrin complex(GO:0008305)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.4	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.0	GO:1990462	omegasome(GO:1990462)
0.0	0.5	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.3	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.3	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	0.3	GO:0097001	ceramide binding(GO:0097001)
0.1	0.5	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.5	GO:0039706	co-receptor binding(GO:0039706)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.2	GO:0030172	troponin C binding(GO:0030172)
0.1	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.3	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	0.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.5	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.5	GO:0030553	cGMP binding(GO:0030553)
0.0	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.0	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.6	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.0	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0022841	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:0052713	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.0	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.5	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	PID AURORA A PATHWAY	Aurora A signaling
0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions