Project
ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Sox5_Sry

Z-value: 0.95

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Transcription factors associated with Sox5_Sry

Gene Symbol Gene ID Gene Info
ENSMUSG00000041540.10 Sox5
ENSMUSG00000069036.3 Sry

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Sox5chr6_143941281_14394174755740.279825-0.711.3e-09Click!
Sox5chr6_144251334_144251522418600.208507-0.671.8e-08Click!
Sox5chr6_144209964_1442106607440.796140-0.656.9e-08Click!
Sox5chr6_144251546_144251744420770.207798-0.658.4e-08Click!
Sox5chr6_144251849_144252061423870.206787-0.641.4e-07Click!

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_178471923_178472101 2.26 Cdh26
cadherin-like 26
11382
0.22
chr10_60351822_60352131 2.26 Vsir
V-set immunoregulatory receptor
2653
0.28
chr11_69062573_69063351 1.84 9330160F10Rik
RIKEN cDNA 9330160F10 gene
2479
0.1
chr4_130715764_130715925 1.74 Snord85
small nucleolar RNA, C/D box 85
33790
0.11
chr2_28598572_28599148 1.67 Gm22675
predicted gene, 22675
3733
0.13
chr4_150890043_150890216 1.66 Park7
Parkinson disease (autosomal recessive, early onset) 7
11706
0.14
chr1_193156667_193156839 1.63 Irf6
interferon regulatory factor 6
84
0.95
chr5_130200680_130200989 1.59 Rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
6219
0.1
chr12_112585016_112585203 1.55 Inf2
inverted formin, FH2 and WH2 domain containing
3675
0.18
chr7_35350340_35350583 1.52 Rhpn2
rhophilin, Rho GTPase binding protein 2
16131
0.13
chr17_86313458_86313775 1.48 2010106C02Rik
RIKEN cDNA 2010106C02 gene
26438
0.23
chr2_22587496_22588353 1.47 Gm13341
predicted gene 13341
38
0.95
chr3_94783418_94783615 1.47 Cgn
cingulin
2935
0.17
chr12_76558245_76558525 1.46 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
3853
0.17
chr15_96455910_96456125 1.44 Scaf11
SR-related CTD-associated factor 11
4783
0.23
chr7_16792307_16792658 1.43 Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
545
0.64
chr1_179854274_179854595 1.35 Ahctf1
AT hook containing transcription factor 1
50754
0.12
chr3_121346684_121346842 1.34 Gm5711
predicted gene 5711
33916
0.12
chr3_136610301_136610480 1.33 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
59734
0.13
chr16_32563013_32563416 1.32 Gm34680
predicted gene, 34680
11472
0.14
chr4_115514141_115514292 1.31 Cyp4a10
cytochrome P450, family 4, subfamily a, polypeptide 10
4048
0.14
chr1_167802317_167803268 1.30 Lmx1a
LIM homeobox transcription factor 1 alpha
113235
0.07
chr7_123430155_123430354 1.29 Lcmt1
leucine carboxyl methyltransferase 1
2394
0.29
chr4_59292306_59292644 1.29 Susd1
sushi domain containing 1
23491
0.17
chr2_171633456_171634007 1.28 Gm26489
predicted gene, 26489
327300
0.01
chr5_144317459_144317816 1.26 Baiap2l1
BAI1-associated protein 2-like 1
28730
0.12
chr2_103466992_103467253 1.26 Cat
catalase
18003
0.16
chr11_57998862_57999212 1.24 Larp1
La ribonucleoprotein domain family, member 1
10027
0.15
chr10_80435784_80436272 1.23 Tcf3
transcription factor 3
2381
0.14
chr1_24615430_24615609 1.22 Gm28661
predicted gene 28661
46
0.86
chr6_14185920_14186504 1.20 Gm23760
predicted gene, 23760
72896
0.11
chr2_132846257_132847404 1.20 Crls1
cardiolipin synthase 1
142
0.79
chr4_141131586_141132124 1.19 Szrd1
SUZ RNA binding domain containing 1
7872
0.11
chr1_88044901_88045120 1.19 AC087801.1
UDP glycosyltransferase 1 family (Ytg1) pseudogene
7410
0.08
chr13_41403888_41404241 1.19 Gm48570
predicted gene, 48570
1773
0.3
chr3_148422779_148423056 1.18 Gm43576
predicted gene 43576
32024
0.22
chr18_64182836_64182987 1.18 St8sia3os
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand
14107
0.15
chr8_33987076_33987405 1.16 Gm45817
predicted gene 45817
40
0.96
chr2_163586914_163587109 1.16 Ttpal
tocopherol (alpha) transfer protein-like
15303
0.13
chr12_84084567_84084718 1.15 Gm8385
predicted gene 8385
2999
0.12
chr10_123048822_123048979 1.14 Mon2
MON2 homolog, regulator of endosome to Golgi trafficking
15769
0.19
chr14_31433815_31434149 1.14 Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
2083
0.25
chr5_32132959_32134082 1.13 Gm10463
predicted gene 10463
349
0.83
chr2_14176921_14177097 1.13 Tmem236
transmembrane protein 236
2486
0.22
chr10_26828769_26829098 1.13 Arhgap18
Rho GTPase activating protein 18
6331
0.25
chr7_100590312_100590463 1.12 Mrpl48
mitochondrial ribosomal protein L48
1039
0.35
chr16_95926674_95926827 1.12 1600002D24Rik
RIKEN cDNA 1600002D24 gene
2327
0.28
chr5_73313719_73313877 1.09 Gm42732
predicted gene 42732
2434
0.16
chr11_94365445_94365605 1.09 Abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
2398
0.24
chr12_91849475_91849887 1.07 Sel1l
sel-1 suppressor of lin-12-like (C. elegans)
524
0.73
chr4_128805691_128806359 1.05 Zfp362
zinc finger protein 362
20
0.97
chr3_89998220_89998476 1.05 Hax1
HCLS1 associated X-1
14
0.85
chr19_58050434_58050717 1.04 Mir5623
microRNA 5623
592
0.82
chr11_58021710_58021982 1.04 Larp1
La ribonucleoprotein domain family, member 1
12782
0.15
chr1_172903375_172903674 1.04 Apcs
serum amyloid P-component
8483
0.16
chr1_155030934_155031254 1.04 Gm29441
predicted gene 29441
645
0.72
chr10_93143358_93143676 1.03 Cdk17
cyclin-dependent kinase 17
17358
0.17
chr11_54804054_54804205 1.03 Lyrm7os
LYR motif containing 7, opposite strand
15790
0.12
chr1_72255145_72255783 1.02 Gm25939
predicted gene, 25939
456
0.72
chr7_123420015_123420410 1.01 Lcmt1
leucine carboxyl methyltransferase 1
2069
0.31
chr8_122742393_122743116 1.01 C230057M02Rik
RIKEN cDNA C230057M02 gene
4243
0.12
chr3_103801587_103801856 1.00 Gm15471
predicted gene 15471
1408
0.2
chr7_45097569_45097720 0.99 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
5423
0.05
chr5_109844725_109844919 0.98 Gm10416
predicted pseudogene 10416
10677
0.17
chr5_22348847_22349031 0.98 Reln
reelin
4237
0.17
chr19_29066936_29067376 0.98 Gm9895
predicted gene 9895
191
0.91
chr7_134690071_134690222 0.98 Dock1
dedicator of cytokinesis 1
19024
0.22
chr3_148420483_148420859 0.97 Gm43576
predicted gene 43576
34270
0.21
chr17_34118027_34118475 0.97 Brd2
bromodomain containing 2
238
0.72
chr16_45644024_45644312 0.96 Gm49585
predicted gene, 49585
1811
0.28
chr14_64689914_64690065 0.96 Kif13b
kinesin family member 13B
37387
0.15
chr7_132308529_132308892 0.95 Gm44891
predicted gene 44891
5368
0.15
chr10_96235024_96235388 0.95 4930459C07Rik
RIKEN cDNA 4930459C07 gene
8999
0.2
chr2_68934625_68935021 0.94 Cers6
ceramide synthase 6
12437
0.14
chr3_137941200_137941383 0.94 Dapp1
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
13422
0.1
chr4_150493335_150493527 0.94 Rere
arginine glutamic acid dipeptide (RE) repeats
5038
0.27
chr4_132863078_132863284 0.94 Stx12
syntaxin 12
79
0.95
chr6_13052400_13052710 0.93 Gm5300
predicted gene 5300
4042
0.25
chr19_3995581_3995732 0.93 Tbx10
T-box 10
2904
0.08
chr17_59012796_59013456 0.92 Nudt12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
142
0.96
chr6_134678296_134678471 0.92 Gm44017
predicted gene, 44017
11476
0.14
chr5_125406078_125406690 0.92 Dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
9513
0.11
chr1_74027469_74027800 0.92 Tns1
tensin 1
9499
0.23
chr12_84963175_84963419 0.92 Arel1
apoptosis resistant E3 ubiquitin protein ligase 1
2733
0.18
chr11_79229715_79229866 0.91 Wsb1
WD repeat and SOCS box-containing 1
13159
0.16
chr19_46532071_46532499 0.91 Arl3
ADP-ribosylation factor-like 3
10528
0.14
chr19_58043550_58043869 0.91 Mir5623
microRNA 5623
7458
0.28
chr17_43504311_43504617 0.90 Mep1a
meprin 1 alpha
1652
0.36
chr12_84202046_84202444 0.90 Gm31513
predicted gene, 31513
6276
0.11
chr16_47171563_47171714 0.90 Gm18169
predicted gene, 18169
40732
0.21
chr4_138065957_138066120 0.90 Eif4g3
eukaryotic translation initiation factor 4 gamma, 3
61286
0.1
chr6_5156932_5157313 0.90 Pon1
paraoxonase 1
36641
0.14
chr2_91537896_91538139 0.89 Ckap5
cytoskeleton associated protein 5
8303
0.15
chr1_67116639_67117125 0.89 Cps1
carbamoyl-phosphate synthetase 1
6144
0.25
chr15_79323845_79324092 0.89 Pla2g6
phospholipase A2, group VI
402
0.74
chr11_75948882_75949196 0.89 Rph3al
rabphilin 3A-like (without C2 domains)
10610
0.2
chr7_128460110_128460271 0.89 Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
1019
0.35
chr16_32008367_32008518 0.88 Senp5
SUMO/sentrin specific peptidase 5
5155
0.1
chr7_81739113_81739266 0.87 Gm18806
predicted gene, 18806
3156
0.16
chr17_24848922_24849092 0.87 Fahd1
fumarylacetoacetate hydrolase domain containing 1
1357
0.2
chr5_66073877_66074050 0.87 Gm43775
predicted gene 43775
1068
0.4
chr14_79451589_79452546 0.87 Kbtbd6
kelch repeat and BTB (POZ) domain containing 6
232
0.9
chr9_99098900_99099051 0.86 Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
40950
0.12
chr13_90799208_90799500 0.86 Gm47521
predicted gene, 47521
21271
0.19
chr6_143154565_143154716 0.86 Gm31108
predicted gene, 31108
709
0.61
chr9_108338578_108339700 0.86 Gpx1
glutathione peroxidase 1
85
0.89
chr11_69967024_69967389 0.86 Cldn7
claudin 7
288
0.7
chr5_67572619_67572866 0.86 1700025A08Rik
RIKEN cDNA 1700025A08 gene
35084
0.11
chr8_120543978_120544129 0.85 Mir7687
microRNA 7687
5357
0.12
chr1_88049227_88049378 0.85 Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
6086
0.08
chr3_122814605_122814890 0.84 4930447N08Rik
RIKEN cDNA 4930447N08 gene
12699
0.14
chr18_8644320_8645204 0.84 Gm35232
predicted gene, 35232
34289
0.18
chr5_139384476_139384627 0.84 Gpr146
G protein-coupled receptor 146
3970
0.13
chr7_70515380_70515786 0.83 Gm44811
predicted gene 44811
15639
0.13
chr19_17328336_17328491 0.83 Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
7023
0.23
chr3_10136204_10136355 0.82 Gm37308
predicted gene, 37308
46324
0.08
chr9_70848458_70848648 0.82 Gm3436
predicted pseudogene 3436
4023
0.25
chr5_147894219_147894411 0.82 Slc46a3
solute carrier family 46, member 3
500
0.77
chr16_87366227_87366378 0.82 N6amt1
N-6 adenine-specific DNA methyltransferase 1 (putative)
12057
0.19
chr4_117682587_117682738 0.81 Dmap1
DNA methyltransferase 1-associated protein 1
389
0.81
chr7_97790389_97790572 0.81 Pak1
p21 (RAC1) activated kinase 1
1939
0.34
chr7_143500903_143501124 0.81 Phlda2
pleckstrin homology like domain, family A, member 2
1528
0.26
chr5_86173166_86173471 0.81 Uba6
ubiquitin-like modifier activating enzyme 6
515
0.78
chr10_21612801_21612952 0.80 1700020N01Rik
RIKEN cDNA 1700020N01 gene
3444
0.3
chr11_12036502_12038049 0.80 Grb10
growth factor receptor bound protein 10
126
0.97
chr16_58519486_58519656 0.80 St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
3773
0.22
chr10_51453996_51454265 0.80 Gm46189
predicted gene, 46189
1850
0.26
chr3_60094748_60095038 0.80 Sucnr1
succinate receptor 1
12991
0.19
chr11_113223856_113224035 0.80 4732490B19Rik
RIKEN cDNA 4732490B19 gene
14276
0.24
chr1_170479226_170479433 0.80 Nos1ap
nitric oxide synthase 1 (neuronal) adaptor protein
24415
0.21
chr5_148789072_148789662 0.79 4930505K14Rik
RIKEN cDNA 4930505K14 gene
11404
0.15
chr7_4806720_4807013 0.79 Ube2s
ubiquitin-conjugating enzyme E2S
4253
0.09
chr13_93192635_93192963 0.79 Tent2
terminal nucleotidyltransferase 2
414
0.86
chr18_23815450_23815627 0.79 Gm23207
predicted gene, 23207
1833
0.32
chr4_137772776_137772971 0.78 Alpl
alkaline phosphatase, liver/bone/kidney
3053
0.26
chr5_114551218_114551384 0.78 Gm13790
predicted gene 13790
12
0.97
chr13_112833681_112833853 0.78 Plpp1
phospholipid phosphatase 1
32904
0.12
chr10_41205379_41205541 0.78 Gm25526
predicted gene, 25526
10585
0.2
chr11_69073513_69073915 0.78 Snord118
small nucleolar RNA, C/D box 118
287
0.63
chr15_103479382_103479548 0.78 Nckap1l
NCK associated protein 1 like
317
0.85
chr17_31079187_31079338 0.77 Gm25447
predicted gene, 25447
19658
0.12
chr6_72396903_72397079 0.77 Vamp8
vesicle-associated membrane protein 8
6288
0.1
chr10_39907400_39907573 0.77 Gm8911
predicted gene 8911
3663
0.13
chr5_151165148_151165337 0.77 Stard13
StAR-related lipid transfer (START) domain containing 13
24908
0.21
chr1_167354724_167354875 0.77 Aldh9a1
aldehyde dehydrogenase 9, subfamily A1
4487
0.14
chr5_4019546_4019718 0.77 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
3783
0.23
chr14_98084865_98085016 0.77 Gm16331
predicted gene 16331
33569
0.21
chr16_77027071_77027249 0.77 Usp25
ubiquitin specific peptidase 25
13373
0.21
chr2_133455802_133456121 0.77 Gm14100
predicted gene 14100
7157
0.23
chr8_66363123_66363725 0.77 Marchf1
membrane associated ring-CH-type finger 1
22870
0.19
chr3_117873618_117873778 0.76 Snx7
sorting nexin 7
4762
0.22
chr15_77882572_77883557 0.76 Txn2
thioredoxin 2
32636
0.11
chr2_103749241_103749406 0.76 Nat10
N-acetyltransferase 10
5966
0.14
chr4_132484893_132485044 0.76 Med18
mediator complex subunit 18
21047
0.08
chr9_31851792_31852171 0.75 Gm31497
predicted gene, 31497
54012
0.11
chr13_77548432_77549057 0.75 Gm9634
predicted gene 9634
5629
0.31
chr17_46735053_46735204 0.75 Cnpy3
canopy FGF signaling regulator 3
2499
0.14
chr12_55054945_55055220 0.74 2700097O09Rik
RIKEN cDNA 2700097O09 gene
981
0.4
chr17_31474444_31474595 0.74 Pde9a
phosphodiesterase 9A
3467
0.12
chr9_61120633_61120784 0.74 Gm33914
predicted gene, 33914
6323
0.15
chr11_50292225_50292589 0.74 Maml1
mastermind like transcriptional coactivator 1
96
0.95
chr4_98318734_98319169 0.73 0610025J13Rik
RIKEN cDNA 0610025J13 gene
2447
0.26
chr5_123014528_123014681 0.73 Orai1
ORAI calcium release-activated calcium modulator 1
470
0.39
chr6_129212899_129213056 0.73 2310001H17Rik
RIKEN cDNA 2310001H17 gene
20997
0.1
chr1_128608127_128608278 0.73 Cxcr4
chemokine (C-X-C motif) receptor 4
15909
0.21
chr6_31148348_31148689 0.73 Gm37728
predicted gene, 37728
1099
0.4
chr10_18371017_18371277 0.73 Nhsl1
NHS-like 1
19175
0.19
chr12_39885382_39885668 0.73 Gm4263
predicted gene 4263
10075
0.21
chr15_99130441_99130592 0.72 Gm25183
predicted gene, 25183
2656
0.15
chr17_64609838_64610010 0.72 Man2a1
mannosidase 2, alpha 1
9188
0.26
chr11_29514525_29514826 0.72 Prorsd1
prolyl-tRNA synthetase domain containing 1
356
0.49
chr19_47461497_47461648 0.72 Sh3pxd2a
SH3 and PX domains 2A
2675
0.27
chr8_107109103_107109254 0.71 C630050I24Rik
RIKEN cDNA C630050I24 gene
9932
0.11
chr11_96397203_96397354 0.71 Gm11531
predicted gene 11531
5166
0.12
chr7_132772857_132773208 0.71 Fam53b
family with sequence similarity 53, member B
3884
0.24
chr19_36793588_36793739 0.71 Gm50112
predicted gene, 50112
24985
0.17
chr11_108309813_108310102 0.71 Apoh
apolipoprotein H
33397
0.16
chr17_47428847_47429237 0.71 Gm50461
predicted gene, 50461
7162
0.11
chr6_40635278_40635429 0.71 Mgam
maltase-glucoamylase
6522
0.16
chr12_108857921_108858072 0.71 Gm22079
predicted gene, 22079
4673
0.11
chr18_79781586_79781737 0.71 Gm19062
predicted gene, 19062
80238
0.07
chr5_139101902_139102053 0.71 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
10667
0.18
chr7_29180085_29180886 0.71 Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
4
0.94
chr16_91292688_91293239 0.71 Olig1
oligodendrocyte transcription factor 1
23191
0.11
chr7_108933988_108934499 0.71 Eif3f
eukaryotic translation initiation factor 3, subunit F
174
0.91
chr5_52782674_52783192 0.71 Zcchc4
zinc finger, CCHC domain containing 4
121
0.97
chr5_100368601_100368752 0.71 Sec31a
Sec31 homolog A (S. cerevisiae)
4406
0.19
chr6_29267024_29267197 0.71 Hilpda
hypoxia inducible lipid droplet associated
5378
0.13
chr13_43525454_43525719 0.71 Gm32939
predicted gene, 32939
4634
0.16
chr6_129513372_129513692 0.70 Tmem52b
transmembrane protein 52B
919
0.35
chr11_53424916_53425067 0.70 Leap2
liver-expressed antimicrobial peptide 2
1821
0.16
chr4_144895166_144895503 0.70 Dhrs3
dehydrogenase/reductase (SDR family) member 3
2115
0.35
chr13_43236620_43236988 0.70 Tbc1d7
TBC1 domain family, member 7
65303
0.1
chr4_151044619_151045451 0.70 Per3
period circadian clock 3
370
0.84
chr2_6129008_6129159 0.70 Proser2
proline and serine rich 2
1056
0.45
chr15_58743876_58744227 0.70 Gm20712
predicted gene 20712
37900
0.14
chr6_145761297_145761448 0.69 Rassf8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
10801
0.2
chr6_125342392_125342543 0.69 Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
6895
0.12
chr11_97241392_97241543 0.69 Npepps
aminopeptidase puromycin sensitive
399
0.8
chr2_173026305_173026589 0.69 Rbm38
RNA binding motif protein 38
3397
0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Sox5_Sry

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0006742 NADP catabolic process(GO:0006742)
0.3 1.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 0.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 0.7 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 0.9 GO:0021764 amygdala development(GO:0021764)
0.2 1.2 GO:0015825 L-serine transport(GO:0015825)
0.2 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2 0.7 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.4 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.5 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.5 GO:0051031 tRNA transport(GO:0051031)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.3 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.6 GO:0048539 bone marrow development(GO:0048539)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.3 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.1 0.3 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.1 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.2 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.3 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.6 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.2 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.1 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.1 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.1 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.1 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.6 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.2 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.0 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0060509 Type I pneumocyte differentiation(GO:0060509)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0036492 regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.0 0.2 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0043328 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.2 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 1.4 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 1.3 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0072040 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.2 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1903659 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.0 0.1 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0034137 positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0010963 regulation of L-arginine import(GO:0010963)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.2 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0061623 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.3 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.0 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0000237 leptotene(GO:0000237)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.0 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.2 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0 0.0 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:1903818 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:1903393 positive regulation of adherens junction organization(GO:1903393)
0.0 0.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.0 0.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0018904 ether metabolic process(GO:0018904)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.2 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.5 GO:0000578 embryonic axis specification(GO:0000578)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.0 GO:0006868 glutamine transport(GO:0006868)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.0 GO:2000409 regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
0.0 0.1 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.0 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.3 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.0 GO:0061450 trophoblast cell migration(GO:0061450)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.0 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370)
0.0 0.0 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.0 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0033136 serine phosphorylation of STAT3 protein(GO:0033136)
0.0 0.2 GO:0070873 regulation of glycogen metabolic process(GO:0070873)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.0 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.0 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.0 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.0 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.0 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.0 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.0 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.0 GO:1901201 regulation of extracellular matrix assembly(GO:1901201)
0.0 0.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097413 Lewy body(GO:0097413)
0.2 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.4 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.2 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.0 GO:0005818 aster(GO:0005818)
0.0 0.2 GO:0031970 nuclear envelope lumen(GO:0005641) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.0 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.0 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.0 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.0 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.9 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.2 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.3 GO:0042731 PH domain binding(GO:0042731)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.4 GO:0070251 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0043842 Kdo transferase activity(GO:0043842)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0018585 fluorene oxygenase activity(GO:0018585)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0016749 N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.4 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity(GO:0018423)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.5 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.0 GO:0036403 2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.9 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 1.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.0 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0034843 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 1.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.0 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.0 GO:0002046 opsin binding(GO:0002046)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.8 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.0 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis