Project
ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tal1

Z-value: 43.90

Motif logo

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Transcription factors associated with Tal1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028717.6 Tal1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Tal1chr4_115048309_11504847580340.1559660.953.7e-28Click!
Tal1chr4_115059412_11505962180.9721500.922.6e-23Click!
Tal1chr4_115056446_1150568612270.9153480.928.8e-23Click!
Tal1chr4_115047820_11504805684880.1546970.921.3e-22Click!
Tal1chr4_115057189_115057563620.9677780.898.4e-20Click!

Activity of the Tal1 motif across conditions

Conditions sorted by the z-value of the Tal1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_29815389_29815572 284.38 Eml6
echinoderm microtubule associated protein like 6
6182
0.16
chr11_32245695_32246028 256.32 Nprl3
nitrogen permease regulator-like 3
4317
0.12
chr7_80208686_80209443 251.95 Gm45206
predicted gene 45206
330
0.78
chr12_88984393_88984775 242.12 Nrxn3
neurexin III
31185
0.23
chr14_46539820_46540205 234.50 E130120K24Rik
RIKEN cDNA E130120K24 gene
16291
0.12
chr5_23922914_23923135 230.92 Fam126a
family with sequence similarity 126, member A
120
0.95
chr11_31831386_31831912 225.58 Gm12107
predicted gene 12107
1011
0.55
chr6_67161663_67162061 224.57 A430010J10Rik
RIKEN cDNA A430010J10 gene
3062
0.22
chr3_30765691_30766002 222.91 Samd7
sterile alpha motif domain containing 7
9624
0.14
chr8_105820906_105821324 222.88 Ranbp10
RAN binding protein 10
6090
0.09
chr12_110974333_110974713 219.76 Ankrd9
ankyrin repeat domain 9
3732
0.14
chr16_56071732_56071993 217.92 Gm24047
predicted gene, 24047
1299
0.31
chr6_70727412_70727666 217.52 Igkj5
immunoglobulin kappa joining 5
3653
0.15
chrX_162679005_162679180 215.81 Gm15203
predicted gene 15203
85
0.96
chr15_93372828_93373012 215.48 Zcrb1
zinc finger CCHC-type and RNA binding motif 1
15224
0.16
chr15_103251687_103251873 214.16 Nfe2
nuclear factor, erythroid derived 2
93
0.94
chr5_52712758_52713046 212.97 Pi4k2b
phosphatidylinositol 4-kinase type 2 beta
28672
0.15
chr12_76673740_76674235 212.30 Sptb
spectrin beta, erythrocytic
36036
0.15
chr4_134981994_134982157 209.96 Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
51065
0.11
chr15_97379586_97379766 209.25 Pced1b
PC-esterase domain containing 1B
18459
0.24
chr13_101611824_101612000 208.50 Gm29341
predicted gene 29341
5679
0.22
chr11_102365077_102365683 206.30 Slc4a1
solute carrier family 4 (anion exchanger), member 1
100
0.94
chr8_23054025_23054342 205.66 Ank1
ankyrin 1, erythroid
4076
0.2
chr6_58642386_58642566 204.93 Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
1894
0.39
chr1_33630885_33631502 204.42 Prim2
DNA primase, p58 subunit
7869
0.14
chr15_5658919_5659100 204.30 Gm18715
predicted gene, 18715
55025
0.14
chr1_127756612_127756781 204.29 Acmsd
amino carboxymuconate semialdehyde decarboxylase
61
0.97
chr13_95679618_95679929 204.09 Iqgap2
IQ motif containing GTPase activating protein 2
2551
0.2
chr5_22348437_22348700 203.29 Reln
reelin
3866
0.17
chr14_32146198_32146521 202.80 Msmb
beta-microseminoprotein
1228
0.33
chr18_32542304_32542816 201.13 Gypc
glycophorin C
7142
0.21
chr1_55946905_55947229 200.96 Gm36986
predicted gene, 36986
13689
0.22
chr11_4553637_4553951 199.96 Mtmr3
myotubularin related protein 3
7526
0.17
chr13_83344551_83344924 198.52 Gm48156
predicted gene, 48156
155028
0.04
chr10_11323594_11323775 197.08 Gm48666
predicted gene, 48666
6731
0.15
chr12_111517954_111518283 196.45 Gm40578
predicted gene, 40578
17278
0.1
chrX_140953732_140953903 196.24 Psmd10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
2872
0.24
chr19_60386923_60387224 195.56 Prlhr
prolactin releasing hormone receptor
81231
0.09
chr15_80910888_80911184 193.87 Tnrc6b
trinucleotide repeat containing 6b
4880
0.17
chr14_60654080_60654264 193.53 Spata13
spermatogenesis associated 13
19417
0.21
chr16_48252848_48253236 193.38 Gm49770
predicted gene, 49770
8772
0.18
chr7_99594452_99594625 192.73 Arrb1
arrestin, beta 1
55
0.96
chr13_20150160_20150481 191.86 Elmo1
engulfment and cell motility 1
34887
0.21
chr5_96951661_96952003 190.58 Gm43144
predicted gene 43144
11535
0.1
chr15_93372582_93372767 189.69 Zcrb1
zinc finger CCHC-type and RNA binding motif 1
15470
0.16
chr7_115830920_115831237 189.44 Sox6
SRY (sex determining region Y)-box 6
6368
0.31
chr15_34983305_34983512 189.19 Stk3
serine/threonine kinase 3
16514
0.26
chr12_76670569_76670894 189.05 Sptb
spectrin beta, erythrocytic
39292
0.14
chr5_151418628_151418887 188.04 Gm42906
predicted gene 42906
9406
0.16
chr7_75830381_75830681 186.53 Klhl25
kelch-like 25
17779
0.18
chr6_148603565_148603734 184.94 Gm6313
predicted gene 6313
6084
0.21
chr14_63062234_63062642 183.78 Defb42
defensin beta 42
7365
0.12
chr8_128688649_128689204 182.55 Itgb1
integrin beta 1 (fibronectin receptor beta)
3056
0.24
chr11_117797537_117797802 182.43 6030468B19Rik
RIKEN cDNA 6030468B19 gene
9
0.94
chr2_181419480_181419646 182.11 Zbtb46
zinc finger and BTB domain containing 46
4825
0.11
chr2_164760159_164760320 181.81 Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
6100
0.08
chr3_116859439_116859612 181.19 Frrs1
ferric-chelate reductase 1
42
0.96
chr10_95569556_95569732 179.81 Nudt4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
5498
0.14
chr2_121037044_121037214 179.77 Epb42
erythrocyte membrane protein band 4.2
57
0.95
chr2_28602260_28602441 179.06 Gm22824
predicted gene, 22824
5845
0.11
chr18_77704753_77705042 179.06 8030462N17Rik
RIKEN cDNA 8030462N17 gene
9036
0.14
chr13_95671451_95671789 178.93 Iqgap2
IQ motif containing GTPase activating protein 2
101
0.96
chr2_158141871_158142558 178.42 Tgm2
transglutaminase 2, C polypeptide
2478
0.23
chr1_157695278_157695646 178.32 Gm38213
predicted gene, 38213
73326
0.09
chrX_101287598_101287912 178.25 Med12
mediator complex subunit 12
1731
0.2
chr7_123462053_123462460 176.40 Aqp8
aquaporin 8
35
0.98
chr7_128854662_128855004 176.38 Gm25778
predicted gene, 25778
28486
0.15
chr5_96989015_96989192 175.81 Gm9484
predicted gene 9484
8261
0.13
chr9_58657759_58658148 175.36 Rec114
REC114 meiotic recombination protein
1339
0.42
chr7_133698079_133698264 175.05 Uros
uroporphyrinogen III synthase
91
0.95
chr4_93481257_93481600 174.65 Gm23443
predicted gene, 23443
63849
0.13
chr8_120371766_120372131 174.44 Gm22715
predicted gene, 22715
71601
0.09
chr7_120875272_120875461 174.35 Gm15774
predicted gene 15774
68
0.93
chr8_122286979_122287274 174.26 Zfpm1
zinc finger protein, multitype 1
4985
0.17
chr4_151960522_151960830 174.18 Dnajc11
DnaJ heat shock protein family (Hsp40) member C11
3533
0.16
chr13_59814367_59814542 173.37 Tut7
terminal uridylyl transferase 7
4948
0.12
chr19_32476101_32476290 173.33 Minpp1
multiple inositol polyphosphate histidine phosphatase 1
9574
0.14
chr5_115267246_115267406 172.20 Gm13831
predicted gene 13831
4233
0.09
chr17_83651316_83651614 171.87 Kcng3
potassium voltage-gated channel, subfamily G, member 3
19570
0.22
chr11_105366062_105366358 171.87 Gm11638
predicted gene 11638
2958
0.23
chr11_102363647_102363997 171.79 Slc4a1
solute carrier family 4 (anion exchanger), member 1
118
0.93
chr15_62159095_62159287 171.42 Pvt1
Pvt1 oncogene
18984
0.25
chr11_31861192_31861524 171.30 Cpeb4
cytoplasmic polyadenylation element binding protein 4
10853
0.19
chr6_38341755_38341991 171.20 Zc3hav1
zinc finger CCCH type, antiviral 1
12400
0.13
chr4_46854042_46854371 171.13 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
5696
0.29
chr7_100844413_100844706 170.99 Relt
RELT tumor necrosis factor receptor
10870
0.14
chr14_69318389_69318982 170.57 Gm16677
predicted gene, 16677
18397
0.08
chr10_62342649_62342920 170.53 Hk1
hexokinase 1
62
0.96
chr3_19650569_19650855 170.32 Trim55
tripartite motif-containing 55
6204
0.16
chr17_48272064_48272554 170.19 Treml4
triggering receptor expressed on myeloid cells-like 4
130
0.94
chr5_149649169_149649529 169.99 Gm20005
predicted gene, 20005
7739
0.14
chr8_33734991_33735310 169.84 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
1707
0.27
chr15_56623570_56623885 169.81 Has2os
hyaluronan synthase 2, opposite strand
66217
0.12
chr16_12697258_12697682 169.47 Gm38619
predicted gene, 38619
6898
0.28
chr17_25089285_25089469 169.42 Ift140
intraflagellar transport 140
1294
0.29
chr15_78922683_78922995 169.07 Lgals1
lectin, galactose binding, soluble 1
3886
0.09
chr10_63272949_63273252 169.03 Gm47615
predicted gene, 47615
3010
0.16
chr18_61960597_61960886 168.76 Sh3tc2
SH3 domain and tetratricopeptide repeats 2
7657
0.21
chr13_99108120_99108286 168.72 Gm807
predicted gene 807
7442
0.18
chr19_6132479_6132770 168.47 Snx15
sorting nexin 15
4320
0.07
chr16_36062065_36062536 168.35 Fam162a
family with sequence similarity 162, member A
9069
0.11
chr3_84772122_84772299 168.13 Fbxw7
F-box and WD-40 domain protein 7
43058
0.17
chr2_119605466_119605626 168.05 Oip5os1
Opa interacting protein 5, opposite strand 1
11243
0.1
chr6_86077923_86078088 167.91 Add2
adducin 2 (beta)
52
0.96
chr9_124138054_124138419 167.58 Ccr5
chemokine (C-C motif) receptor 5
9488
0.21
chr1_43414347_43414515 167.47 Gm29041
predicted gene 29041
4847
0.23
chr10_17590195_17590550 167.15 Gm47770
predicted gene, 47770
63458
0.1
chr3_103196500_103196848 166.97 2410024N13Rik
RIKEN cDNA 2410024N13 gene
2301
0.22
chr5_147441974_147442285 166.42 Gm42883
predicted gene 42883
2739
0.14
chr5_105565875_105566288 166.08 Lrrc8c
leucine rich repeat containing 8 family, member C
7223
0.2
chr10_41209082_41209401 165.81 Gm25526
predicted gene, 25526
6804
0.21
chr8_123988622_123988985 165.08 Abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
5681
0.11
chr11_4543369_4543542 165.07 Mtmr3
myotubularin related protein 3
2813
0.24
chr14_69304834_69305018 164.55 Synb
syncytin b
10627
0.09
chr14_69523086_69523268 164.54 Gm27179
predicted gene 27179
10628
0.1
chr8_68606713_68606995 163.86 Gm15654
predicted gene 15654
13284
0.25
chr4_93583749_93583913 163.70 Gm12640
predicted gene 12640
15355
0.19
chr9_64044981_64045602 163.42 Gm25606
predicted gene, 25606
3205
0.17
chr18_21283772_21283949 163.34 Garem1
GRB2 associated regulator of MAPK1 subtype 1
16263
0.17
chr19_17323425_17323682 162.97 Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
11883
0.21
chr14_47522434_47522734 162.78 Fbxo34
F-box protein 34
3495
0.15
chr2_28598073_28598473 162.75 Gm22675
predicted gene, 22675
3146
0.14
chr1_161894692_161894863 162.44 Gm31925
predicted gene, 31925
2630
0.23
chr10_93143358_93143676 162.38 Cdk17
cyclin-dependent kinase 17
17358
0.17
chr17_84776723_84776893 162.10 Lrpprc
leucine-rich PPR-motif containing
735
0.64
chr15_73212141_73212465 161.92 Ptk2
PTK2 protein tyrosine kinase 2
2812
0.25
chr3_108096711_108096990 161.70 Gnat2
guanine nucleotide binding protein, alpha transducing 2
393
0.71
chr4_109445455_109445982 161.34 Ttc39a
tetratricopeptide repeat domain 39A
24776
0.14
chr5_120136253_120136600 161.06 Gm10390
predicted gene 10390
2835
0.27
chr16_34031697_34031893 160.93 Kalrn
kalirin, RhoGEF kinase
15301
0.19
chr1_191855569_191855746 160.69 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
28509
0.11
chr2_103893863_103894037 160.47 Gm13876
predicted gene 13876
5626
0.13
chr3_144670267_144670456 159.90 Sh3glb1
SH3-domain GRB2-like B1 (endophilin)
27106
0.13
chr3_127889681_127889845 159.83 Fam241a
family with sequence similarity 241, member A
6525
0.13
chr7_103877202_103877483 159.50 Olfr66
olfactory receptor 66
4899
0.07
chr16_90988770_90988947 159.44 Gm15965
predicted gene 15965
4951
0.12
chr5_75460472_75460800 159.32 Gm42800
predicted gene 42800
61264
0.11
chr18_15345573_15345724 159.23 A830021F12Rik
RIKEN cDNA A830021F12 gene
6286
0.21
chr15_36321999_36322330 158.60 Rpl7a-ps3
ribosomal protein L7A, pseudogene 3
13220
0.12
chr15_83423666_83423948 158.49 Pacsin2
protein kinase C and casein kinase substrate in neurons 2
17
0.97
chr14_45653782_45654098 158.30 Ddhd1
DDHD domain containing 1
3420
0.14
chr18_34516209_34516494 158.25 n-R5s24
nuclear encoded rRNA 5S 24
6614
0.15
chr9_22453602_22453960 158.19 Gm17545
predicted gene, 17545
509
0.68
chr4_24644850_24645009 157.88 Klhl32
kelch-like 32
30498
0.21
chr2_167043430_167043751 157.72 Znfx1
zinc finger, NFX1-type containing 1
95
0.93
chr14_47321701_47321992 157.38 Gm49190
predicted gene, 49190
790
0.44
chr4_116193969_116194265 157.24 Llph-ps1
LLP homolog, pseudogene 1
6835
0.1
chr9_43234311_43234858 156.87 Oaf
out at first homolog
5327
0.16
chr6_5291230_5291963 156.62 Pon2
paraoxonase 2
2528
0.26
chr18_25097087_25097280 156.45 Fhod3
formin homology 2 domain containing 3
27178
0.22
chr6_70730875_70731236 156.03 Igkj5
immunoglobulin kappa joining 5
7169
0.13
chr13_99019946_99020104 155.89 A930014D07Rik
RIKEN cDNA A930014D07 gene
12926
0.12
chr1_58954126_58954299 155.62 Trak2
trafficking protein, kinesin binding 2
7875
0.16
chr16_97006668_97006833 155.46 Gm32432
predicted gene, 32432
87993
0.09
chr1_154033942_154034127 155.22 Gm28286
predicted gene 28286
267
0.91
chr9_14369323_14369628 155.16 Endod1
endonuclease domain containing 1
11508
0.12
chr2_33843200_33843519 155.00 Nron
non-protein coding RNA, repressor of NFAT
37500
0.15
chr11_121239715_121240038 154.72 Narf
nuclear prelamin A recognition factor
2623
0.17
chr17_33713331_33713621 153.97 Marchf2
membrane associated ring-CH-type finger 2
95
0.94
chr12_55051961_55052112 153.90 2700097O09Rik
RIKEN cDNA 2700097O09 gene
2065
0.2
chr16_31598355_31598677 153.85 Gm34256
predicted gene, 34256
5296
0.18
chr4_148204076_148204384 153.78 Fbxo2
F-box protein 2
43609
0.08
chr3_131728746_131728905 153.07 Gm29865
predicted gene, 29865
30980
0.22
chr16_91441869_91442151 153.01 Gm46562
predicted gene, 46562
16411
0.09
chr9_67024874_67025223 152.87 Tpm1
tropomyosin 1, alpha
7777
0.18
chr4_109411064_109411374 152.72 Ttc39a
tetratricopeptide repeat domain 39A
3557
0.19
chr15_82184037_82184673 152.56 Gm49502
predicted gene, 49502
1161
0.29
chr10_100574875_100575154 152.52 Gm47956
predicted gene, 47956
2412
0.2
chr10_42265100_42265393 152.38 Foxo3
forkhead box O3
6880
0.27
chr11_85339500_85339819 152.33 Bcas3
breast carcinoma amplified sequence 3
13508
0.19
chr4_59533305_59533500 152.30 Gm12529
predicted gene 12529
655
0.67
chr4_42867543_42867734 152.09 Fam205c
family with sequence similarity 205, member C
6083
0.14
chr1_73072668_73072833 151.88 1700027A15Rik
RIKEN cDNA 1700027A15 gene
48181
0.15
chr12_80778227_80778545 151.56 Gm47941
predicted gene, 47941
11957
0.12
chr12_111443494_111443821 151.29 Tnfaip2
tumor necrosis factor, alpha-induced protein 2
667
0.58
chr7_127767294_127767484 151.15 Orai3
ORAI calcium release-activated calcium modulator 3
2426
0.11
chrX_164164755_164165040 151.01 Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
2719
0.26
chr11_95011990_95012348 150.97 Samd14
sterile alpha motif domain containing 14
1888
0.21
chr11_16503276_16503437 150.96 Sec61g
SEC61, gamma subunit
1688
0.39
chr19_8603137_8603306 150.96 Slc22a8
solute carrier family 22 (organic anion transporter), member 8
11932
0.1
chrX_85614770_85615135 150.75 Gm44378
predicted gene, 44378
25975
0.18
chr8_121899242_121899545 150.60 Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
2891
0.15
chr8_122309305_122309664 150.47 Zfpm1
zinc finger protein, multitype 1
2164
0.24
chr16_58454803_58455144 150.45 Dcbld2
discoidin, CUB and LCCL domain containing 2
218
0.94
chr9_64590624_64590805 150.36 Megf11
multiple EGF-like-domains 11
43815
0.17
chr14_69321815_69322332 150.09 Gm16677
predicted gene, 16677
15009
0.09
chr14_69540059_69540582 150.04 Gm27174
predicted gene 27174
15012
0.09
chr19_37238054_37238331 149.96 Gm25268
predicted gene, 25268
4708
0.16
chr16_21996984_21997165 149.13 Liph
lipase, member H
1411
0.37
chr8_119918152_119918328 149.13 Usp10
ubiquitin specific peptidase 10
7383
0.17
chr13_75733796_75734110 149.04 Gm48302
predicted gene, 48302
6674
0.14
chr16_49800061_49800448 148.98 Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
279
0.89
chr14_20599676_20599956 148.96 Usp54
ubiquitin specific peptidase 54
5514
0.13
chr3_102165876_102166166 148.90 Vangl1
VANGL planar cell polarity 1
81
0.96
chr6_29701091_29701386 148.81 Tspan33
tetraspanin 33
6790
0.18
chr13_44663056_44663676 148.76 Gm47805
predicted gene, 47805
41184
0.16
chr3_105808565_105808856 148.53 Gm5547
predicted gene 5547
6830
0.11
chr3_142884736_142884993 148.37 9530052C20Rik
RIKEN cDNA 9530052C20 gene
2369
0.19
chr7_100466963_100467472 148.33 Gm10603
predicted gene 10603
27
0.95
chr14_69536637_69537045 148.24 Gm27174
predicted gene 27174
18491
0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
103.0 411.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
99.4 497.0 GO:0015722 canalicular bile acid transport(GO:0015722)
96.0 384.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
93.0 278.9 GO:0060375 regulation of mast cell differentiation(GO:0060375)
84.0 251.9 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
83.7 251.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
80.3 80.3 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
71.5 286.2 GO:0008228 opsonization(GO:0008228)
66.9 133.8 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
65.2 260.9 GO:0070836 caveola assembly(GO:0070836)
64.7 194.2 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
63.7 127.4 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
62.9 314.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
62.7 313.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
61.0 305.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
60.8 364.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
59.6 238.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
55.4 1164.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
55.4 277.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
54.7 218.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
54.0 161.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
53.3 266.4 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
53.2 159.6 GO:0046149 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
52.8 211.1 GO:0050904 diapedesis(GO:0050904)
52.6 262.8 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
51.5 463.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
50.9 458.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
50.6 101.2 GO:0018992 germ-line sex determination(GO:0018992)
49.8 199.4 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
48.2 96.5 GO:0048388 endosomal lumen acidification(GO:0048388)
46.7 186.8 GO:0023021 termination of signal transduction(GO:0023021)
46.0 138.0 GO:0018343 protein farnesylation(GO:0018343)
46.0 229.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
45.5 182.0 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
45.3 45.3 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
45.3 90.7 GO:0048194 Golgi vesicle budding(GO:0048194)
45.2 135.7 GO:0035973 aggrephagy(GO:0035973)
44.4 133.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
43.4 217.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
43.1 43.1 GO:0012502 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
42.9 128.6 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
42.6 170.5 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
42.6 170.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
42.5 42.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
42.3 169.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
41.4 41.4 GO:0031047 gene silencing by RNA(GO:0031047)
41.2 123.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
41.0 163.8 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
40.5 202.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
40.2 321.3 GO:0060352 cell adhesion molecule production(GO:0060352)
39.9 79.8 GO:1990705 cholangiocyte proliferation(GO:1990705)
39.9 159.5 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649)
39.1 117.4 GO:0070627 ferrous iron import(GO:0070627)
39.0 117.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
38.6 38.6 GO:0046349 amino sugar biosynthetic process(GO:0046349)
38.6 38.6 GO:0032808 lacrimal gland development(GO:0032808)
38.3 38.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
38.2 114.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
38.1 152.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
38.0 228.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
38.0 38.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
37.9 75.7 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
37.8 113.5 GO:0006741 NADP biosynthetic process(GO:0006741)
37.8 75.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
37.8 37.8 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
37.7 75.5 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
37.7 188.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
37.5 225.2 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
37.4 149.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
37.4 224.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
37.2 148.9 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
37.0 592.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
36.9 147.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
36.8 110.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
36.5 36.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
36.3 218.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
36.3 761.6 GO:0048821 erythrocyte development(GO:0048821)
36.0 647.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
35.9 179.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
35.8 35.8 GO:0007431 salivary gland development(GO:0007431)
35.4 176.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
35.4 106.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
35.1 105.2 GO:0021553 olfactory nerve development(GO:0021553)
35.0 70.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
34.5 137.9 GO:0032264 IMP salvage(GO:0032264)
33.8 169.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
33.5 100.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
33.2 33.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
33.0 66.0 GO:0001543 ovarian follicle rupture(GO:0001543)
33.0 131.9 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
32.8 65.7 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
32.6 130.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
32.6 65.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
32.5 97.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
32.4 97.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
31.9 223.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
31.7 126.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
31.7 95.2 GO:1903416 response to glycoside(GO:1903416)
31.7 95.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
31.7 95.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
31.7 158.4 GO:0015879 carnitine transport(GO:0015879)
31.7 221.6 GO:0043320 natural killer cell degranulation(GO:0043320)
31.6 189.5 GO:0010815 bradykinin catabolic process(GO:0010815)
31.3 125.4 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
31.2 125.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
31.0 93.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
30.8 123.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
30.4 91.2 GO:0001555 oocyte growth(GO:0001555)
30.2 120.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
29.8 89.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
29.7 89.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
29.6 118.3 GO:0071918 urea transmembrane transport(GO:0071918)
29.4 29.4 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
29.3 117.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
29.1 58.2 GO:0046618 drug export(GO:0046618)
28.8 86.4 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
28.8 86.3 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
28.7 286.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
28.6 57.1 GO:0032898 neurotrophin production(GO:0032898)
28.5 85.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
28.4 85.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
28.3 84.8 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
28.2 140.9 GO:0046485 ether lipid metabolic process(GO:0046485)
27.8 111.4 GO:0061113 pancreas morphogenesis(GO:0061113)
27.7 110.9 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
27.4 109.7 GO:0070669 response to interleukin-2(GO:0070669)
27.3 136.7 GO:0009642 response to light intensity(GO:0009642)
27.2 190.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
27.2 81.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
27.2 108.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
27.1 135.4 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
26.9 134.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
26.9 268.8 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
26.8 214.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
26.6 133.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
26.3 131.5 GO:0015671 oxygen transport(GO:0015671)
26.1 52.1 GO:0008050 female courtship behavior(GO:0008050)
26.0 78.1 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
25.9 51.8 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
25.9 103.4 GO:0030916 otic vesicle formation(GO:0030916)
25.5 25.5 GO:0044004 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
25.4 25.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
25.3 151.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
25.2 100.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
25.1 50.2 GO:0032782 bile acid secretion(GO:0032782)
25.1 75.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
25.1 225.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
25.0 224.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
24.9 99.7 GO:0072675 osteoclast fusion(GO:0072675)
24.8 99.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
24.8 49.5 GO:0043173 nucleotide salvage(GO:0043173)
24.7 74.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
24.7 49.4 GO:0043379 memory T cell differentiation(GO:0043379)
24.7 24.7 GO:0003091 renal water homeostasis(GO:0003091)
24.6 49.3 GO:0052055 modulation by symbiont of host molecular function(GO:0052055)
24.4 97.8 GO:0015781 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
24.4 73.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
24.4 73.2 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
24.2 48.4 GO:0042908 xenobiotic transport(GO:0042908)
24.2 169.2 GO:0045332 phospholipid translocation(GO:0045332)
24.0 24.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
24.0 383.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
23.9 95.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
23.7 47.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
23.7 71.0 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
23.6 94.3 GO:0021943 formation of radial glial scaffolds(GO:0021943)
23.5 70.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
23.3 419.2 GO:0006144 purine nucleobase metabolic process(GO:0006144)
23.3 69.8 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
23.2 139.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
23.1 46.3 GO:0070827 chromatin maintenance(GO:0070827)
23.0 69.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
23.0 344.7 GO:0006828 manganese ion transport(GO:0006828)
22.9 45.8 GO:0007386 compartment pattern specification(GO:0007386)
22.9 22.9 GO:0044532 modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) modulation by symbiont of host programmed cell death(GO:0052040) modulation by symbiont of host apoptotic process(GO:0052150) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433)
22.5 67.4 GO:0061511 centriole elongation(GO:0061511)
22.5 67.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
22.4 44.9 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
22.4 89.5 GO:0015705 iodide transport(GO:0015705)
22.3 111.7 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
22.1 88.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
22.1 66.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
22.0 263.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
22.0 22.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
21.9 65.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
21.9 87.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
21.9 87.6 GO:0090527 actin filament reorganization(GO:0090527)
21.9 65.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
21.9 43.8 GO:2000978 regulation of forebrain neuron differentiation(GO:2000977) negative regulation of forebrain neuron differentiation(GO:2000978)
21.8 65.5 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
21.8 109.2 GO:0045908 negative regulation of vasodilation(GO:0045908)
21.8 43.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
21.7 65.2 GO:0060931 sinoatrial node cell development(GO:0060931)
21.7 21.7 GO:0006114 glycerol biosynthetic process(GO:0006114)
21.7 43.4 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
21.6 64.8 GO:0036394 amylase secretion(GO:0036394)
21.5 21.5 GO:0061515 myeloid cell development(GO:0061515)
21.5 21.5 GO:0010544 negative regulation of platelet activation(GO:0010544)
21.4 42.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
21.4 64.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
21.2 63.7 GO:0006481 C-terminal protein methylation(GO:0006481)
21.1 42.3 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
21.1 42.3 GO:0036258 multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
21.0 42.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309)
20.9 41.8 GO:0051293 establishment of spindle localization(GO:0051293)
20.9 41.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
20.8 186.8 GO:0031507 heterochromatin assembly(GO:0031507)
20.7 145.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
20.7 62.0 GO:1902065 response to L-glutamate(GO:1902065)
20.6 103.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
20.6 61.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
20.4 142.8 GO:0046085 adenosine metabolic process(GO:0046085)
20.4 61.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
20.3 121.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
20.3 40.5 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
20.2 121.5 GO:0060263 regulation of respiratory burst(GO:0060263)
20.2 80.7 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
20.1 40.3 GO:1901563 response to camptothecin(GO:1901563)
20.0 40.0 GO:0046874 quinolinate metabolic process(GO:0046874)
20.0 139.8 GO:0071318 cellular response to ATP(GO:0071318)
20.0 79.9 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
19.8 59.5 GO:0006624 vacuolar protein processing(GO:0006624)
19.8 59.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
19.7 39.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
19.7 78.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
19.5 39.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
19.4 77.8 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
19.4 58.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
19.4 38.8 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
19.3 58.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
19.3 115.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
19.3 19.3 GO:0032006 regulation of TOR signaling(GO:0032006)
19.2 38.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
19.2 76.7 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
19.2 38.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
19.0 38.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
19.0 95.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
19.0 38.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
19.0 57.0 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
19.0 94.9 GO:0016266 O-glycan processing(GO:0016266)
18.9 75.8 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
18.6 37.3 GO:0070487 monocyte aggregation(GO:0070487)
18.5 55.5 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
18.5 18.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
18.4 184.3 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
18.4 128.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
18.4 55.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
18.3 73.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
18.2 36.4 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
18.2 54.5 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069) glandular epithelial cell maturation(GO:0002071)
18.1 36.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
18.1 108.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
18.1 72.4 GO:0051697 protein delipidation(GO:0051697)
18.1 18.1 GO:0045914 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
18.1 36.2 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
18.0 90.0 GO:0040016 embryonic cleavage(GO:0040016)
17.9 179.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
17.9 161.0 GO:0071361 cellular response to ethanol(GO:0071361)
17.9 17.9 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
17.8 71.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
17.8 71.3 GO:0006004 fucose metabolic process(GO:0006004)
17.8 53.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
17.8 35.5 GO:0072718 response to cisplatin(GO:0072718)
17.8 17.8 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
17.7 124.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
17.7 88.5 GO:0006572 tyrosine catabolic process(GO:0006572)
17.7 159.2 GO:0008343 adult feeding behavior(GO:0008343)
17.7 53.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
17.7 35.3 GO:0043101 purine-containing compound salvage(GO:0043101)
17.7 17.7 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
17.6 35.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
17.6 123.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
17.6 333.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
17.5 17.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
17.5 105.1 GO:0007220 Notch receptor processing(GO:0007220)
17.5 87.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
17.4 86.9 GO:0036233 glycine import(GO:0036233)
17.3 69.3 GO:0003383 apical constriction(GO:0003383)
17.2 17.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
17.2 51.6 GO:0002572 pro-T cell differentiation(GO:0002572)
17.2 86.0 GO:0015816 glycine transport(GO:0015816)
17.1 85.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
17.1 34.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
17.1 188.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
17.1 34.2 GO:0061687 detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to copper ion(GO:1990169)
17.1 51.3 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
17.0 51.0 GO:0000087 mitotic M phase(GO:0000087)
16.9 33.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
16.9 33.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
16.9 67.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
16.9 50.7 GO:0040031 snRNA modification(GO:0040031)
16.9 67.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
16.9 168.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
16.9 67.4 GO:0001887 selenium compound metabolic process(GO:0001887)
16.9 50.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
16.8 134.8 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
16.8 50.5 GO:0034214 protein hexamerization(GO:0034214)
16.8 50.5 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
16.8 83.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
16.7 33.4 GO:0009080 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
16.6 16.6 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
16.6 49.8 GO:1900368 regulation of RNA interference(GO:1900368)
16.6 82.8 GO:1903376 neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
16.6 198.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
16.5 66.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
16.5 115.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
16.5 49.6 GO:0009946 proximal/distal axis specification(GO:0009946)
16.5 16.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
16.5 115.2 GO:0021860 pyramidal neuron development(GO:0021860)
16.4 115.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
16.4 49.3 GO:0021564 vagus nerve development(GO:0021564)
16.4 49.2 GO:0031049 programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
16.4 81.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
16.3 48.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
16.3 81.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
16.2 113.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
16.2 32.4 GO:0042126 nitrate metabolic process(GO:0042126)
16.2 48.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
16.1 80.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
16.1 64.5 GO:0018101 protein citrullination(GO:0018101)
16.1 112.9 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
16.0 96.2 GO:0006561 proline biosynthetic process(GO:0006561)
16.0 31.9 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
15.9 47.7 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
15.9 127.2 GO:0009437 carnitine metabolic process(GO:0009437)
15.9 349.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
15.9 190.5 GO:0032310 prostaglandin secretion(GO:0032310)
15.8 47.5 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
15.8 31.6 GO:0034137 positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
15.8 78.9 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
15.8 31.5 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
15.7 15.7 GO:0030279 negative regulation of ossification(GO:0030279)
15.7 31.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
15.7 31.3 GO:0051660 establishment of centrosome localization(GO:0051660)
15.7 31.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
15.6 31.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
15.6 46.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
15.6 109.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
15.6 31.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
15.6 311.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
15.4 46.3 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
15.3 92.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
15.3 45.8 GO:0046208 spermine catabolic process(GO:0046208)
15.3 15.3 GO:0035330 regulation of hippo signaling(GO:0035330)
15.2 60.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
15.2 45.7 GO:1904431 positive regulation of t-circle formation(GO:1904431)
15.1 60.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
15.1 15.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
15.1 60.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
15.1 30.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
15.1 30.1 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
15.1 105.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
15.0 150.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
14.9 29.9 GO:1902075 cellular response to salt(GO:1902075)
14.9 119.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
14.9 44.7 GO:0019532 oxalate transport(GO:0019532)
14.9 44.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
14.8 59.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
14.8 14.8 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
14.7 147.2 GO:0090330 regulation of platelet aggregation(GO:0090330)
14.7 102.9 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
14.7 44.0 GO:0036438 maintenance of lens transparency(GO:0036438)
14.7 308.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
14.7 29.3 GO:0090168 Golgi reassembly(GO:0090168)
14.6 117.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
14.6 219.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
14.6 160.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
14.6 174.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
14.5 421.9 GO:0070527 platelet aggregation(GO:0070527)
14.5 14.5 GO:0042505 tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
14.5 101.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
14.5 29.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
14.5 43.5 GO:0034627 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
14.5 14.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
14.5 43.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
14.5 14.5 GO:0070889 platelet alpha granule organization(GO:0070889)
14.4 14.4 GO:0090231 regulation of spindle checkpoint(GO:0090231)
14.4 43.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
14.4 86.3 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
14.4 14.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
14.4 129.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
14.4 43.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
14.3 14.3 GO:0050923 regulation of negative chemotaxis(GO:0050923)
14.2 42.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
14.2 28.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
14.2 170.5 GO:0051601 exocyst localization(GO:0051601)
14.2 14.2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
14.2 42.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
14.1 198.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
14.1 42.4 GO:0001692 histamine metabolic process(GO:0001692)
14.1 70.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
14.1 14.1 GO:0034204 lipid translocation(GO:0034204)
14.1 70.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
14.0 14.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
14.0 98.2 GO:0006778 porphyrin-containing compound metabolic process(GO:0006778)
14.0 14.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
14.0 98.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
14.0 28.0 GO:0006068 ethanol catabolic process(GO:0006068)
14.0 28.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
14.0 14.0 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
14.0 223.5 GO:0016075 rRNA catabolic process(GO:0016075)
14.0 41.9 GO:0015886 heme transport(GO:0015886)
14.0 335.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
14.0 69.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
14.0 41.9 GO:1904683 regulation of metalloendopeptidase activity(GO:1904683)
13.9 111.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
13.9 41.7 GO:0032202 telomere assembly(GO:0032202)
13.9 83.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
13.9 41.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
13.8 540.0 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
13.8 41.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
13.7 13.7 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
13.7 137.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
13.7 54.8 GO:0006007 glucose catabolic process(GO:0006007)
13.7 82.2 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
13.6 27.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
13.6 13.6 GO:0032466 negative regulation of cytokinesis(GO:0032466)
13.5 27.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
13.5 27.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
13.4 13.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
13.4 13.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
13.4 120.6 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
13.4 160.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
13.4 53.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
13.3 66.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
13.3 26.6 GO:0070266 necroptotic process(GO:0070266)
13.3 291.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
13.3 66.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
13.2 39.6 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
13.2 39.5 GO:0006545 glycine biosynthetic process(GO:0006545)
13.2 26.3 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
13.1 13.1 GO:0002125 maternal aggressive behavior(GO:0002125)
13.1 26.3 GO:0006551 leucine metabolic process(GO:0006551)
13.1 13.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
13.0 156.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
13.0 26.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
13.0 39.1 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
13.0 234.4 GO:0018345 protein palmitoylation(GO:0018345)
13.0 26.0 GO:0032289 central nervous system myelin formation(GO:0032289)
13.0 51.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
13.0 51.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
13.0 77.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
13.0 129.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
12.9 12.9 GO:0060700 regulation of ribonuclease activity(GO:0060700)
12.9 25.8 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
12.8 141.1 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
12.8 64.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
12.8 25.6 GO:0070459 prolactin secretion(GO:0070459)
12.8 38.4 GO:0007525 somatic muscle development(GO:0007525)
12.8 140.7 GO:0035455 response to interferon-alpha(GO:0035455)
12.7 140.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
12.7 229.0 GO:0006491 N-glycan processing(GO:0006491)
12.7 12.7 GO:0070350 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
12.7 12.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
12.7 25.3 GO:0002215 defense response to nematode(GO:0002215)
12.6 37.9 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
12.6 101.0 GO:0070307 lens fiber cell development(GO:0070307)
12.6 25.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
12.6 37.8 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
12.6 37.8 GO:0000966 RNA 5'-end processing(GO:0000966)
12.6 62.9 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
12.5 37.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
12.5 37.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
12.5 12.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
12.5 24.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
12.5 137.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
12.5 99.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
12.5 149.6 GO:0045070 positive regulation of viral genome replication(GO:0045070)
12.5 74.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
12.4 37.3 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
12.4 49.8 GO:0070475 rRNA base methylation(GO:0070475)
12.4 62.1 GO:1902969 mitotic DNA replication(GO:1902969)
12.4 24.8 GO:0051409 response to nitrosative stress(GO:0051409)
12.4 24.8 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
12.4 49.6 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
12.4 12.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
12.4 24.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
12.3 148.1 GO:0000305 response to oxygen radical(GO:0000305)
12.3 61.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
12.3 12.3 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
12.3 135.6 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
12.3 37.0 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
12.3 110.8 GO:0090207 regulation of triglyceride metabolic process(GO:0090207)
12.3 24.6 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
12.2 36.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
12.2 122.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
12.2 280.4 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
12.2 73.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
12.2 36.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
12.2 12.2 GO:0032439 endosome localization(GO:0032439)
12.2 60.8 GO:0061635 regulation of protein complex stability(GO:0061635)
12.1 12.1 GO:0055094 response to lipoprotein particle(GO:0055094)
12.1 12.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
12.1 48.3 GO:0050917 sensory perception of umami taste(GO:0050917)
12.0 12.0 GO:0030259 lipid glycosylation(GO:0030259)
12.0 35.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
12.0 35.9 GO:0046112 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleobase biosynthetic process(GO:0046112)
12.0 35.9 GO:0007296 vitellogenesis(GO:0007296)
11.9 191.0 GO:0030488 tRNA methylation(GO:0030488)
11.9 23.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
11.9 23.8 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
11.9 83.1 GO:0030575 nuclear body organization(GO:0030575)
11.8 23.7 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
11.8 35.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
11.8 23.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
11.8 59.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
11.8 129.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
11.8 105.9 GO:0032801 receptor catabolic process(GO:0032801)
11.8 141.0 GO:0010842 retina layer formation(GO:0010842)
11.7 47.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
11.7 199.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
11.7 117.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
11.7 70.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
11.7 23.4 GO:0043691 reverse cholesterol transport(GO:0043691)
11.7 23.4 GO:0072611 interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) regulation of interleukin-13 secretion(GO:2000665)
11.7 11.7 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
11.7 23.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
11.7 81.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
11.6 58.2 GO:0018904 ether metabolic process(GO:0018904)
11.6 11.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
11.6 465.0 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
11.6 23.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
11.6 46.4 GO:0051138 regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
11.6 57.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
11.6 23.1 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
11.6 11.6 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
11.5 138.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
11.5 23.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
11.5 34.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990)
11.5 80.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
11.5 34.4 GO:0015889 cobalamin transport(GO:0015889)
11.5 45.8 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
11.5 11.5 GO:0006522 alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078)
11.4 22.9 GO:0019042 viral latency(GO:0019042)
11.4 22.8 GO:1901421 positive regulation of response to alcohol(GO:1901421)
11.4 11.4 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
11.3 11.3 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
11.3 33.8 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
11.2 56.2 GO:0019695 choline metabolic process(GO:0019695)
11.2 56.2 GO:0001842 neural fold formation(GO:0001842)
11.2 11.2 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
11.2 33.7 GO:0016554 cytidine to uridine editing(GO:0016554)
11.2 22.5 GO:0032570 response to progesterone(GO:0032570)
11.2 44.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
11.2 22.4 GO:0034587 piRNA metabolic process(GO:0034587)
11.2 22.4 GO:0071839 apoptotic process in bone marrow(GO:0071839) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
11.2 33.6 GO:0090045 positive regulation of deacetylase activity(GO:0090045) regulation of histone deacetylase activity(GO:1901725)
11.2 11.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
11.2 44.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
11.2 67.0 GO:0044351 macropinocytosis(GO:0044351)
11.1 33.4 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
11.1 55.5 GO:0015807 L-amino acid transport(GO:0015807)
11.1 122.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
11.1 22.2 GO:2000909 sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909)
11.1 33.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
11.1 132.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
11.1 11.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
11.0 154.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
11.0 11.0 GO:0042359 vitamin D metabolic process(GO:0042359)
11.0 11.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
10.9 87.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
10.9 21.8 GO:0046292 formaldehyde metabolic process(GO:0046292)
10.9 76.1 GO:0006670 sphingosine metabolic process(GO:0006670)
10.9 21.7 GO:0071462 cellular response to water stimulus(GO:0071462)
10.9 54.3 GO:0048268 clathrin coat assembly(GO:0048268)
10.8 65.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
10.8 10.8 GO:0021516 dorsal spinal cord development(GO:0021516)
10.8 356.9 GO:0043039 tRNA aminoacylation(GO:0043039)
10.8 108.1 GO:0030149 sphingolipid catabolic process(GO:0030149)
10.8 43.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
10.8 75.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
10.8 140.4 GO:0015858 nucleoside transport(GO:0015858)
10.8 54.0 GO:0042023 DNA endoreduplication(GO:0042023)
10.8 10.8 GO:1902188 positive regulation of viral release from host cell(GO:1902188)
10.8 21.6 GO:1902473 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
10.8 21.5 GO:0051099 positive regulation of binding(GO:0051099)
10.7 139.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
10.7 64.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
10.7 32.1 GO:0044838 cell quiescence(GO:0044838)
10.6 31.9 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
10.6 31.8 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044)
10.6 63.6 GO:0007097 nuclear migration(GO:0007097)
10.6 42.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
10.6 10.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
10.6 21.1 GO:2001225 regulation of chloride transport(GO:2001225)
10.5 73.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
10.5 105.3 GO:0001675 acrosome assembly(GO:0001675)
10.5 10.5 GO:0043462 regulation of ATPase activity(GO:0043462)
10.5 42.1 GO:0090009 primitive streak formation(GO:0090009)
10.5 209.9 GO:0006301 postreplication repair(GO:0006301)
10.5 21.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
10.5 41.9 GO:1904181 positive regulation of membrane depolarization(GO:1904181)
10.4 41.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
10.4 83.5 GO:0046686 response to cadmium ion(GO:0046686)
10.4 31.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
10.4 72.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
10.4 20.8 GO:0006824 cobalt ion transport(GO:0006824)
10.4 93.4 GO:0008340 determination of adult lifespan(GO:0008340)
10.4 51.9 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
10.4 31.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
10.4 31.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
10.3 496.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
10.3 31.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
10.3 31.0 GO:0070126 mitochondrial translational termination(GO:0070126)
10.3 10.3 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
10.3 390.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
10.3 10.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
10.3 51.3 GO:0006528 asparagine metabolic process(GO:0006528)
10.3 10.3 GO:1904177 regulation of adipose tissue development(GO:1904177)
10.3 61.5 GO:0031167 rRNA methylation(GO:0031167)
10.3 82.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
10.2 10.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
10.2 20.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
10.2 20.4 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
10.2 30.6 GO:1903671 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
10.2 30.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
10.2 10.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
10.2 122.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
10.2 81.2 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
10.1 40.6 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
10.1 10.1 GO:0010447 response to acidic pH(GO:0010447)
10.1 91.0 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
10.1 50.5 GO:0060056 mammary gland involution(GO:0060056)
10.1 30.3 GO:2000210 positive regulation of anoikis(GO:2000210)
10.1 50.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
10.1 20.2 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
10.1 10.1 GO:0009124 nucleoside monophosphate biosynthetic process(GO:0009124)
10.1 30.2 GO:0072126 positive regulation of glomerular mesangial cell proliferation(GO:0072126)
10.0 60.3 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
10.0 10.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
10.0 19.9 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
10.0 49.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
10.0 39.8 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
9.9 29.8 GO:0031577 spindle checkpoint(GO:0031577)
9.9 19.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
9.9 49.6 GO:0009650 UV protection(GO:0009650)
9.9 238.2 GO:0006730 one-carbon metabolic process(GO:0006730)
9.9 39.6 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
9.9 19.8 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
9.9 49.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
9.8 9.8 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
9.8 19.7 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
9.8 58.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
9.8 49.0 GO:1903392 negative regulation of adherens junction organization(GO:1903392)
9.8 29.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
9.8 19.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
9.7 29.2 GO:0016126 sterol biosynthetic process(GO:0016126)
9.7 29.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
9.7 9.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
9.7 96.6 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
9.7 38.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
9.6 86.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
9.6 9.6 GO:0060982 coronary artery morphogenesis(GO:0060982)
9.6 38.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
9.6 9.6 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
9.6 9.6 GO:0048254 snoRNA localization(GO:0048254)
9.6 38.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
9.6 86.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
9.6 57.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
9.6 47.9 GO:0046218 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
9.6 38.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
9.6 9.6 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
9.5 19.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
9.5 66.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
9.5 19.0 GO:0001865 NK T cell differentiation(GO:0001865)
9.5 37.9 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
9.5 9.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
9.4 75.6 GO:0001771 immunological synapse formation(GO:0001771)
9.4 9.4 GO:2000468 regulation of peroxidase activity(GO:2000468)
9.4 28.3 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
9.4 226.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
9.4 9.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
9.4 9.4 GO:0051974 negative regulation of telomerase activity(GO:0051974)
9.4 9.4 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
9.4 9.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
9.4 337.0 GO:0006611 protein export from nucleus(GO:0006611)
9.3 56.0 GO:1903441 protein localization to ciliary membrane(GO:1903441)
9.3 177.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
9.3 37.3 GO:0099515 actin filament-based transport(GO:0099515)
9.3 28.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
9.3 9.3 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
9.3 18.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
9.3 37.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
9.3 18.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
9.3 27.9 GO:0015825 L-serine transport(GO:0015825)
9.3 9.3 GO:1902992 negative regulation of amyloid precursor protein catabolic process(GO:1902992)
9.3 9.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
9.3 18.6 GO:0016584 nucleosome positioning(GO:0016584)
9.3 18.6 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
9.3 18.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
9.3 18.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
9.3 9.3 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
9.3 18.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
9.3 46.3 GO:0051013 microtubule severing(GO:0051013)
9.2 46.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
9.2 55.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
9.2 18.5 GO:0045055 regulated exocytosis(GO:0045055)
9.2 92.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
9.2 18.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
9.2 18.4 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674)
9.2 46.1 GO:0046697 decidualization(GO:0046697)
9.2 36.8 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
9.2 18.4 GO:1904705 regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874)
9.2 9.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
9.2 36.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
9.2 18.3 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
9.2 54.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
9.1 200.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
9.1 27.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
9.1 36.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
9.1 36.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
9.1 27.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
9.1 54.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
9.1 9.1 GO:0010948 negative regulation of cell cycle process(GO:0010948)
9.1 9.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
9.1 136.0 GO:0010737 protein kinase A signaling(GO:0010737)
9.0 18.1 GO:0046959 habituation(GO:0046959)
9.0 36.2 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
9.0 162.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
9.0 9.0 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
9.0 18.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
9.0 9.0 GO:0015838 amino-acid betaine transport(GO:0015838)
9.0 9.0 GO:0035898 parathyroid hormone secretion(GO:0035898)
9.0 36.0 GO:0048680 positive regulation of axon regeneration(GO:0048680)
9.0 9.0 GO:0016115 terpenoid catabolic process(GO:0016115)
8.9 17.9 GO:1904528 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
8.9 35.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
8.9 17.9 GO:0031642 negative regulation of myelination(GO:0031642)
8.9 17.9 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
8.9 8.9 GO:0035510 DNA dealkylation(GO:0035510) demethylation(GO:0070988)
8.9 62.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
8.9 133.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
8.9 8.9 GO:0003156 regulation of organ formation(GO:0003156)
8.9 8.9 GO:0015817 histidine transport(GO:0015817)
8.9 8.9 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
8.8 17.7 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
8.8 70.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
8.8 61.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
8.8 17.6 GO:0009445 putrescine metabolic process(GO:0009445)
8.8 61.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
8.8 122.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
8.8 26.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
8.7 8.7 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
8.7 61.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
8.7 96.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
8.7 8.7 GO:0002432 granuloma formation(GO:0002432)
8.7 17.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
8.7 8.7 GO:0006536 glutamate metabolic process(GO:0006536)
8.7 26.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
8.7 86.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
8.7 43.3 GO:0031643 positive regulation of myelination(GO:0031643)
8.6 17.3 GO:0051683 establishment of Golgi localization(GO:0051683)
8.6 8.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
8.6 60.5 GO:0010039 response to iron ion(GO:0010039)
8.6 17.3 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
8.6 77.6 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
8.6 51.7 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072)
8.6 17.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
8.6 8.6 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
8.6 180.6 GO:0032456 endocytic recycling(GO:0032456)
8.6 25.7 GO:0030421 defecation(GO:0030421)
8.6 34.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
8.6 25.7 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
8.6 8.6 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
8.6 25.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
8.5 93.9 GO:0009299 mRNA transcription(GO:0009299)
8.5 76.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
8.5 25.6 GO:0002551 mast cell chemotaxis(GO:0002551)
8.5 42.6 GO:0000154 rRNA modification(GO:0000154)
8.5 8.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
8.5 17.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
8.5 76.4 GO:0014044 Schwann cell development(GO:0014044)
8.5 33.9 GO:0051799 negative regulation of hair follicle development(GO:0051799)
8.5 67.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
8.5 42.3 GO:0050915 sensory perception of sour taste(GO:0050915)
8.5 50.7 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
8.4 16.9 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
8.4 25.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
8.4 50.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
8.4 33.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
8.4 16.8 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
8.4 25.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
8.4 16.8 GO:0006971 hypotonic response(GO:0006971) cellular hypotonic response(GO:0071476)
8.4 8.4 GO:0048478 replication fork protection(GO:0048478)
8.4 42.0 GO:0015074 DNA integration(GO:0015074)
8.4 50.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
8.3 33.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
8.3 25.0 GO:0060023 soft palate development(GO:0060023)
8.3 16.7 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
8.3 33.2 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
8.3 224.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
8.3 41.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
8.3 124.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
8.3 16.5 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
8.3 24.8 GO:1905208 negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
8.3 41.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
8.3 57.8 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
8.2 16.5 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
8.2 123.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
8.2 16.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
8.2 41.1 GO:0046415 urate metabolic process(GO:0046415)
8.2 8.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
8.2 8.2 GO:1902548 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
8.2 24.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
8.2 24.5 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
8.2 16.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
8.2 8.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
8.2 203.8 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
8.1 56.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
8.1 8.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
8.1 8.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
8.1 8.1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
8.1 40.4 GO:0032096 negative regulation of response to food(GO:0032096)
8.1 24.2 GO:0045060 negative thymic T cell selection(GO:0045060)
8.1 56.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
8.1 88.8 GO:0034508 centromere complex assembly(GO:0034508)
8.0 16.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
8.0 16.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
8.0 8.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
8.0 8.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
8.0 40.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
8.0 64.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
8.0 8.0 GO:0006942 regulation of striated muscle contraction(GO:0006942)
8.0 16.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
8.0 8.0 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
8.0 159.6 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
8.0 15.9 GO:0009070 serine family amino acid biosynthetic process(GO:0009070)
8.0 15.9 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
8.0 23.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
8.0 39.8 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
8.0 47.7 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
7.9 7.9 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
7.9 7.9 GO:0006983 ER overload response(GO:0006983)
7.9 23.8 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
7.9 23.8 GO:0071545 inositol phosphate catabolic process(GO:0071545)
7.9 245.5 GO:0043966 histone H3 acetylation(GO:0043966)
7.9 7.9 GO:0070189 kynurenine metabolic process(GO:0070189)
7.9 39.5 GO:0015871 choline transport(GO:0015871)
7.9 23.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
7.9 47.4 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
7.9 39.4 GO:0009249 protein lipoylation(GO:0009249)
7.8 23.5 GO:0052547 regulation of peptidase activity(GO:0052547)
7.8 7.8 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
7.8 23.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
7.8 7.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
7.8 54.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
7.7 7.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
7.7 15.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
7.7 15.4 GO:0060081 membrane hyperpolarization(GO:0060081)
7.7 7.7 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
7.7 15.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
7.7 15.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
7.7 7.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
7.7 23.0 GO:0090042 tubulin deacetylation(GO:0090042)
7.7 15.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
7.7 260.6 GO:0006446 regulation of translational initiation(GO:0006446)
7.6 22.8 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
7.6 91.0 GO:0030168 platelet activation(GO:0030168)
7.6 7.6 GO:0016095 polyprenol catabolic process(GO:0016095)
7.6 15.1 GO:0009247 glycolipid biosynthetic process(GO:0009247)
7.6 22.7 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of RIG-I signaling pathway(GO:0039536)
7.6 15.1 GO:0051307 meiotic chromosome separation(GO:0051307)
7.6 7.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
7.5 150.9 GO:0000266 mitochondrial fission(GO:0000266)
7.5 15.1 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
7.5 37.6 GO:0042448 progesterone metabolic process(GO:0042448)
7.5 15.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
7.5 97.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
7.5 22.5 GO:0098535 de novo centriole assembly(GO:0098535)
7.5 15.0 GO:0060613 fat pad development(GO:0060613)
7.5 52.4 GO:1904851 regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
7.5 7.5 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
7.5 22.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
7.5 52.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
7.5 7.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
7.5 37.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
7.5 44.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
7.5 52.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
7.4 14.9 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
7.4 59.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
7.4 7.4 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
7.4 52.0 GO:0043248 proteasome assembly(GO:0043248)
7.4 44.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
7.4 7.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
7.4 14.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
7.4 7.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.4 44.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
7.4 14.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
7.4 7.4 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
7.3 7.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
7.3 14.7 GO:0060018 astrocyte fate commitment(GO:0060018)
7.3 7.3 GO:0045764 positive regulation of cellular amino acid metabolic process(GO:0045764)
7.3 14.7 GO:0006304 DNA modification(GO:0006304)
7.3 73.3 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
7.3 14.6 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
7.3 29.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
7.3 21.9 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
7.3 21.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
7.3 21.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
7.3 29.1 GO:0030321 transepithelial chloride transport(GO:0030321)
7.3 72.7 GO:0001659 temperature homeostasis(GO:0001659)
7.3 79.9 GO:0007035 vacuolar acidification(GO:0007035)
7.3 29.1 GO:0006776 vitamin A metabolic process(GO:0006776)
7.3 7.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
7.3 29.0 GO:0016925 protein sumoylation(GO:0016925)
7.2 21.7 GO:0022417 protein maturation by protein folding(GO:0022417)
7.2 57.8 GO:1902806 regulation of cell cycle G1/S phase transition(GO:1902806)
7.2 86.6 GO:0061436 establishment of skin barrier(GO:0061436)
7.2 7.2 GO:0046060 dATP metabolic process(GO:0046060)
7.2 72.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
7.2 21.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
7.2 43.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
7.2 43.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
7.2 416.0 GO:0006633 fatty acid biosynthetic process(GO:0006633)
7.2 7.2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
7.2 186.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
7.2 200.5 GO:0045454 cell redox homeostasis(GO:0045454)
7.2 35.8 GO:0060484 lung-associated mesenchyme development(GO:0060484)
7.1 71.5 GO:0002115 store-operated calcium entry(GO:0002115)
7.1 28.6 GO:0071569 protein ufmylation(GO:0071569)
7.1 7.1 GO:0060631 regulation of meiosis I(GO:0060631)
7.1 42.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
7.1 255.1 GO:0008654 phospholipid biosynthetic process(GO:0008654)
7.1 14.1 GO:0021540 corpus callosum morphogenesis(GO:0021540)
7.1 77.7 GO:0060972 left/right pattern formation(GO:0060972)
7.1 49.4 GO:0030261 chromosome condensation(GO:0030261)
7.1 21.2 GO:0006013 mannose metabolic process(GO:0006013)
7.0 21.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
7.0 49.3 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
7.0 63.3 GO:0031648 protein destabilization(GO:0031648)
7.0 49.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
7.0 14.0 GO:0046849 bone remodeling(GO:0046849)
7.0 35.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
7.0 21.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
7.0 7.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
7.0 146.6 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
7.0 27.9 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
7.0 62.6 GO:0072528 pyrimidine-containing compound biosynthetic process(GO:0072528)
6.9 34.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
6.9 6.9 GO:0001556 oocyte maturation(GO:0001556)
6.9 13.9 GO:0070314 G1 to G0 transition(GO:0070314)
6.9 13.8 GO:0072205 metanephric collecting duct development(GO:0072205)
6.9 82.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
6.9 6.9 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
6.9 27.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
6.9 171.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
6.9 48.1 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
6.9 6.9 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
6.8 6.8 GO:0030818 negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
6.8 109.5 GO:0006308 DNA catabolic process(GO:0006308)
6.8 102.6 GO:0065002 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
6.8 34.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
6.8 20.5 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
6.8 20.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
6.8 34.0 GO:0006477 protein sulfation(GO:0006477)
6.8 34.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
6.8 20.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
6.8 176.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
6.8 27.1 GO:0006116 NADH oxidation(GO:0006116)
6.8 47.4 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
6.8 13.5 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
6.8 6.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
6.8 6.8 GO:0016574 histone ubiquitination(GO:0016574)
6.7 20.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
6.7 256.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
6.7 13.5 GO:1903578 regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
6.7 6.7 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
6.7 26.9 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
6.7 20.2 GO:0007256 activation of JNKK activity(GO:0007256)
6.7 20.2 GO:0015697 quaternary ammonium group transport(GO:0015697)
6.7 13.4 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
6.7 26.8 GO:0006020 inositol metabolic process(GO:0006020)
6.7 6.7 GO:0071218 cellular response to misfolded protein(GO:0071218)
6.7 26.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
6.7 20.0 GO:0010459 negative regulation of heart rate(GO:0010459)
6.7 40.1 GO:0070875 positive regulation of glycogen metabolic process(GO:0070875)
6.7 6.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
6.7 60.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
6.7 20.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
6.7 33.3 GO:0030033 microvillus assembly(GO:0030033)
6.6 13.3 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.6 46.4 GO:0042574 retinal metabolic process(GO:0042574)
6.6 13.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
6.6 13.2 GO:0034033 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
6.6 52.5 GO:0051450 myoblast proliferation(GO:0051450)
6.6 13.1 GO:0097484 dendrite extension(GO:0097484)
6.5 26.1 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
6.5 71.8 GO:0003351 epithelial cilium movement(GO:0003351)
6.5 430.7 GO:0050691 regulation of defense response to virus by host(GO:0050691)
6.5 39.1 GO:0046549 retinal cone cell development(GO:0046549)
6.5 19.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
6.5 52.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
6.5 19.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
6.5 6.5 GO:0018377 protein myristoylation(GO:0018377)
6.5 25.8 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
6.5 38.7 GO:0014041 regulation of neuron maturation(GO:0014041)
6.4 19.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
6.4 25.8 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958)
6.4 6.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
6.4 32.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
6.4 6.4 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
6.4 102.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
6.4 25.6 GO:0061036 positive regulation of cartilage development(GO:0061036)
6.4 12.8 GO:0001826 inner cell mass cell differentiation(GO:0001826)
6.4 6.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
6.4 12.8 GO:0015884 folic acid transport(GO:0015884)
6.4 25.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
6.4 19.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
6.4 25.5 GO:0006167 AMP biosynthetic process(GO:0006167)
6.4 31.9 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
6.4 57.4 GO:0009595 detection of biotic stimulus(GO:0009595)
6.4 6.4 GO:0033046 negative regulation of sister chromatid segregation(GO:0033046)
6.4 19.1 GO:0046039 GTP metabolic process(GO:0046039)
6.4 6.4 GO:0043038 amino acid activation(GO:0043038)
6.4 38.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
6.3 6.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
6.3 6.3 GO:1901859 negative regulation of mitochondrial DNA metabolic process(GO:1901859)
6.3 25.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
6.3 12.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
6.3 31.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
6.3 44.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
6.3 176.5 GO:0002181 cytoplasmic translation(GO:0002181)
6.3 12.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
6.3 12.6 GO:0044778 meiotic cell cycle checkpoint(GO:0033313) meiotic DNA integrity checkpoint(GO:0044778)
6.3 31.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
6.3 18.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
6.3 6.3 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
6.3 6.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
6.3 50.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
6.3 12.6 GO:0051305 meiotic chromosome movement towards spindle pole(GO:0016344) meiotic cytokinesis(GO:0033206) chromosome movement towards spindle pole(GO:0051305)
6.3 12.5 GO:0001880 Mullerian duct regression(GO:0001880)
6.2 99.9 GO:0017144 drug metabolic process(GO:0017144)
6.2 12.5 GO:0036297 interstrand cross-link repair(GO:0036297)
6.2 49.8 GO:0030500 regulation of bone mineralization(GO:0030500)
6.2 49.5 GO:0051289 protein homotetramerization(GO:0051289)
6.2 24.7 GO:0010165 response to X-ray(GO:0010165)
6.2 74.2 GO:0090630 activation of GTPase activity(GO:0090630)
6.2 6.2 GO:0033131 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
6.2 12.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
6.2 104.9 GO:0051168 nuclear export(GO:0051168)
6.2 67.8 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
6.2 24.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
6.1 12.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
6.1 12.3 GO:0018065 protein-cofactor linkage(GO:0018065)
6.1 6.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
6.1 12.2 GO:0048771 tissue remodeling(GO:0048771)
6.1 18.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
6.1 18.3 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
6.1 6.1 GO:0007028 cytoplasm organization(GO:0007028)
6.1 6.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
6.1 12.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
6.1 12.1 GO:0009063 cellular amino acid catabolic process(GO:0009063)
6.1 6.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
6.1 24.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
6.1 12.1 GO:0032530 regulation of microvillus organization(GO:0032530)
6.1 6.1 GO:0009451 RNA modification(GO:0009451)
6.0 127.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
6.0 30.2 GO:0045141 meiotic telomere clustering(GO:0045141)
6.0 350.1 GO:0016579 protein deubiquitination(GO:0016579)
6.0 6.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
6.0 6.0 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
6.0 36.2 GO:0046326 positive regulation of glucose import(GO:0046326)
6.0 18.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
6.0 522.9 GO:0006310 DNA recombination(GO:0006310)
6.0 120.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
6.0 6.0 GO:0006534 cysteine metabolic process(GO:0006534) homocysteine metabolic process(GO:0050667)
6.0 12.0 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
6.0 29.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
6.0 18.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
6.0 17.9 GO:0035810 positive regulation of urine volume(GO:0035810)
6.0 6.0 GO:0070828 heterochromatin organization(GO:0070828)
6.0 6.0 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
6.0 11.9 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
6.0 6.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
6.0 11.9 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
5.9 5.9 GO:0007599 hemostasis(GO:0007599)
5.9 11.9 GO:0097062 dendritic spine maintenance(GO:0097062)
5.9 17.8 GO:0071407 cellular response to organic cyclic compound(GO:0071407)
5.9 47.4 GO:0042572 retinol metabolic process(GO:0042572)
5.9 5.9 GO:0048148 behavioral response to cocaine(GO:0048148)
5.9 47.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
5.9 11.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
5.9 11.8 GO:0072643 interferon-gamma secretion(GO:0072643)
5.9 5.9 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
5.9 17.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
5.8 5.8 GO:0031268 pseudopodium organization(GO:0031268)
5.8 58.2 GO:0002021 response to dietary excess(GO:0002021)
5.8 5.8 GO:0060591 chondroblast differentiation(GO:0060591)
5.8 11.6 GO:0055088 lipid homeostasis(GO:0055088)
5.8 17.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
5.8 11.5 GO:0016556 mRNA modification(GO:0016556)
5.8 5.8 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
5.8 11.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
5.7 5.7 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
5.7 22.9 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
5.7 5.7 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
5.7 79.8 GO:0044839 cell cycle G2/M phase transition(GO:0044839)
5.7 56.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
5.7 11.4 GO:0032482 Rab protein signal transduction(GO:0032482)
5.7 11.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
5.7 158.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
5.7 11.3 GO:0009093 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
5.6 11.3 GO:0032352 positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
5.6 16.9 GO:0040019 positive regulation of embryonic development(GO:0040019)
5.6 11.3 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
5.6 124.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
5.6 16.9 GO:0046599 regulation of centriole replication(GO:0046599)
5.6 95.8 GO:0046850 regulation of bone remodeling(GO:0046850)
5.6 5.6 GO:0007343 egg activation(GO:0007343)
5.6 28.1 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
5.6 106.6 GO:0007052 mitotic spindle organization(GO:0007052)
5.6 55.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
5.6 66.9 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
5.6 16.7 GO:0045351 type I interferon biosynthetic process(GO:0045351)
5.6 16.7 GO:0007000 nucleolus organization(GO:0007000)
5.6 105.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
5.6 11.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278)
5.6 33.3 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
5.5 44.4 GO:0015693 magnesium ion transport(GO:0015693)
5.5 22.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
5.5 5.5 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
5.5 5.5 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
5.5 5.5 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
5.5 11.0 GO:2000773 negative regulation of cellular senescence(GO:2000773)
5.5 11.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
5.5 16.5 GO:0060405 regulation of penile erection(GO:0060405)
5.5 33.0 GO:0034453 microtubule anchoring(GO:0034453)
5.5 5.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
5.5 16.4 GO:0033273 response to vitamin(GO:0033273)
5.5 27.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
5.5 27.4 GO:0061462 protein localization to lysosome(GO:0061462)
5.4 27.2 GO:0016125 sterol metabolic process(GO:0016125)
5.4 114.1 GO:0032092 positive regulation of protein binding(GO:0032092)
5.4 16.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
5.4 21.7 GO:0006040 amino sugar metabolic process(GO:0006040)
5.4 10.8 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
5.4 5.4 GO:0042503 tyrosine phosphorylation of Stat3 protein(GO:0042503)
5.4 5.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
5.4 16.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
5.4 5.4 GO:0003162 atrioventricular node development(GO:0003162)
5.4 26.9 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
5.4 102.2 GO:0051028 mRNA transport(GO:0051028)
5.4 16.1 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
5.4 21.5 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
5.4 42.9 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
5.4 53.6 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
5.3 42.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
5.3 16.0 GO:0050994 regulation of lipid catabolic process(GO:0050994)
5.3 90.3 GO:0030042 actin filament depolymerization(GO:0030042)
5.3 15.9 GO:0061450 trophoblast cell migration(GO:0061450)
5.3 5.3 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
5.3 105.9 GO:0006829 zinc II ion transport(GO:0006829)
5.3 15.9 GO:0002159 desmosome assembly(GO:0002159)
5.3 5.3 GO:0032026 response to magnesium ion(GO:0032026)
5.3 15.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
5.3 10.6 GO:0009826 unidimensional cell growth(GO:0009826)
5.3 10.6 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
5.3 5.3 GO:0006450 regulation of translational fidelity(GO:0006450)
5.2 26.2 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
5.2 10.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
5.2 162.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
5.2 57.6 GO:0016180 snRNA processing(GO:0016180)
5.2 5.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
5.2 31.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
5.2 125.4 GO:0045576 mast cell activation(GO:0045576)
5.2 10.4 GO:0060068 vagina development(GO:0060068)
5.2 26.1 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
5.2 15.6 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
5.2 5.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
5.2 20.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
5.2 20.8 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
5.2 31.1 GO:0015809 arginine transport(GO:0015809)
5.2 31.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
5.2 72.6 GO:0015804 neutral amino acid transport(GO:0015804)
5.2 5.2 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
5.2 5.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
5.2 77.6 GO:0050873 brown fat cell differentiation(GO:0050873)
5.2 15.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
5.2 20.7 GO:0060177 regulation of angiotensin metabolic process(GO:0060177)
5.2 10.3 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
5.2 5.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
5.2 5.2 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
5.2 5.2 GO:0055119 relaxation of cardiac muscle(GO:0055119)
5.1 113.1 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
5.1 5.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
5.1 25.7 GO:0034063 stress granule assembly(GO:0034063)
5.1 10.3 GO:0090071 regulation of ribosome biogenesis(GO:0090069) negative regulation of ribosome biogenesis(GO:0090071)
5.1 20.5 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
5.1 10.3 GO:0002200 somatic diversification of immune receptors(GO:0002200)
5.1 41.0 GO:0019915 lipid storage(GO:0019915)
5.1 61.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
5.1 5.1 GO:0042045 epithelial fluid transport(GO:0042045)
5.1 5.1 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
5.1 5.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
5.1 40.6 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
5.1 10.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
5.1 10.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
5.1 15.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
5.0 5.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
5.0 75.4 GO:0000075 cell cycle checkpoint(GO:0000075)
5.0 5.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
5.0 15.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
5.0 40.2 GO:0044804 nucleophagy(GO:0044804)
5.0 5.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603) positive regulation of catecholamine secretion(GO:0033605)
5.0 10.0 GO:0051029 rRNA transport(GO:0051029)
5.0 20.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
5.0 5.0 GO:1900015 regulation of cytokine production involved in inflammatory response(GO:1900015)
5.0 24.8 GO:0006694 steroid biosynthetic process(GO:0006694)
5.0 5.0 GO:0019674 NAD metabolic process(GO:0019674)
5.0 59.5 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
5.0 29.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
4.9 19.8 GO:0035855 megakaryocyte development(GO:0035855)
4.9 39.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
4.9 9.9 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
4.9 14.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
4.9 19.8 GO:0033233 regulation of protein sumoylation(GO:0033233)
4.9 19.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
4.9 4.9 GO:0045346 MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346)
4.9 4.9 GO:0000963 mitochondrial RNA processing(GO:0000963)
4.9 9.8 GO:0010755 regulation of plasminogen activation(GO:0010755)
4.9 49.1 GO:0000186 activation of MAPKK activity(GO:0000186)
4.9 9.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
4.9 29.4 GO:0032060 bleb assembly(GO:0032060)
4.9 245.0 GO:0051607 defense response to virus(GO:0051607)
4.9 9.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
4.9 4.9 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
4.9 53.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
4.9 4.9 GO:0034502 protein localization to chromosome(GO:0034502)
4.9 999.2 GO:0008380 RNA splicing(GO:0008380)
4.9 4.9 GO:0090110 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
4.9 209.4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
4.9 403.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
4.8 9.7 GO:0033762 response to glucagon(GO:0033762)
4.8 67.7 GO:0009206 ATP biosynthetic process(GO:0006754) purine nucleoside triphosphate biosynthetic process(GO:0009145) ribonucleoside triphosphate biosynthetic process(GO:0009201) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
4.8 9.7 GO:0031639 plasminogen activation(GO:0031639)
4.8 14.5 GO:0006641 triglyceride metabolic process(GO:0006641)
4.8 19.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
4.8 120.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
4.8 19.3 GO:0032204 regulation of telomere maintenance(GO:0032204)
4.8 4.8 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
4.8 14.5 GO:0070265 necrotic cell death(GO:0070265)
4.8 9.6 GO:0038066 p38MAPK cascade(GO:0038066)
4.8 4.8 GO:0002097 tRNA wobble base modification(GO:0002097)
4.8 4.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
4.8 4.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
4.8 9.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
4.8 14.4 GO:0042732 D-xylose metabolic process(GO:0042732)
4.8 52.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
4.8 19.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
4.8 9.6 GO:0030242 pexophagy(GO:0030242)
4.8 33.4 GO:0008209 androgen metabolic process(GO:0008209)
4.8 47.7 GO:0010508 positive regulation of autophagy(GO:0010508)
4.8 9.5 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
4.8 19.0 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
4.7 4.7 GO:0006102 isocitrate metabolic process(GO:0006102)
4.7 147.0 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
4.7 33.2 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
4.7 23.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
4.7 9.4 GO:0019079 viral genome replication(GO:0019079)
4.7 37.7 GO:0045116 protein neddylation(GO:0045116)
4.7 33.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
4.7 33.0 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
4.7 14.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
4.7 4.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
4.7 9.4 GO:0034421 post-translational protein acetylation(GO:0034421)
4.7 98.6 GO:0031333 negative regulation of protein complex assembly(GO:0031333)
4.7 51.6 GO:0060674 placenta blood vessel development(GO:0060674)
4.7 9.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
4.7 126.5 GO:0051297 centrosome organization(GO:0051297)
4.7 18.7 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
4.7 46.8 GO:0072676 lymphocyte migration(GO:0072676)
4.7 18.7 GO:0006650 glycerophospholipid metabolic process(GO:0006650)
4.7 4.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
4.7 4.7 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
4.6 152.9 GO:0010942 positive regulation of cell death(GO:0010942)
4.6 9.3 GO:0010587 miRNA catabolic process(GO:0010587)
4.6 9.2 GO:0007020 microtubule nucleation(GO:0007020)
4.6 4.6 GO:0045622 regulation of T-helper cell differentiation(GO:0045622)
4.6 18.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
4.6 9.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
4.6 41.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
4.6 9.1 GO:0097264 self proteolysis(GO:0097264)
4.6 13.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
4.5 4.5 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
4.5 9.1 GO:0071397 cellular response to cholesterol(GO:0071397)
4.5 4.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
4.5 9.1 GO:0035729 response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
4.5 18.1 GO:0030225 macrophage differentiation(GO:0030225)
4.5 9.1 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
4.5 9.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
4.5 9.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
4.5 85.6 GO:0035966 response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966)
4.5 18.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
4.5 4.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.5 40.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
4.5 13.4 GO:0042573 retinoic acid metabolic process(GO:0042573)
4.5 13.4 GO:0033136 serine phosphorylation of STAT3 protein(GO:0033136)
4.4 4.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
4.4 8.9 GO:0007144 female meiosis I(GO:0007144)
4.4 8.9 GO:0006903 vesicle targeting(GO:0006903)
4.4 26.6 GO:0030539 male genitalia development(GO:0030539)
4.4 13.3 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
4.4 22.1 GO:0001773 myeloid dendritic cell activation(GO:0001773)
4.4 66.3 GO:0030218 erythrocyte differentiation(GO:0030218)
4.4 8.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
4.4 4.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
4.4 4.4 GO:0030322 stabilization of membrane potential(GO:0030322)
4.4 4.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
4.4 30.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
4.4 30.7 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
4.4 192.3 GO:0008033 tRNA processing(GO:0008033)
4.4 8.7 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
4.3 8.7 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
4.3 21.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
4.3 8.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.3 8.7 GO:0016322 neuron remodeling(GO:0016322)
4.3 21.6 GO:0006835 dicarboxylic acid transport(GO:0006835)
4.3 43.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
4.3 266.4 GO:0016072 rRNA metabolic process(GO:0016072)
4.3 4.3 GO:0061154 endothelial tube morphogenesis(GO:0061154)
4.3 4.3 GO:0070243 regulation of thymocyte apoptotic process(GO:0070243)
4.3 111.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
4.3 29.8 GO:0060412 ventricular septum morphogenesis(GO:0060412)
4.2 25.5 GO:0040014 regulation of multicellular organism growth(GO:0040014)
4.2 8.5 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
4.2 29.7 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
4.2 8.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
4.2 25.4 GO:0010390 histone monoubiquitination(GO:0010390)
4.2 21.1 GO:0030224 monocyte differentiation(GO:0030224)
4.2 21.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
4.2 4.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
4.2 12.6 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
4.2 58.7 GO:0007569 cell aging(GO:0007569)
4.2 50.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
4.2 16.6 GO:0098840 protein transport along microtubule(GO:0098840)
4.2 419.9 GO:0032259 methylation(GO:0032259)
4.2 8.3 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
4.2 74.7 GO:0060976 coronary vasculature development(GO:0060976)
4.1 16.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
4.1 4.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
4.1 4.1 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
4.1 16.6 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
4.1 4.1 GO:0050777 negative regulation of immune response(GO:0050777)
4.1 24.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
4.1 16.5 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
4.1 20.5 GO:0048535 lymph node development(GO:0048535)
4.1 4.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
4.1 8.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
4.1 8.2 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
4.1 4.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
4.1 24.6 GO:0010596 negative regulation of endothelial cell migration(GO:0010596)
4.1 4.1 GO:0040009 regulation of growth rate(GO:0040009)
4.1 4.1 GO:0010259 multicellular organism aging(GO:0010259)
4.1 4.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
4.1 8.1 GO:0070305 response to cGMP(GO:0070305)
4.1 85.2 GO:0009988 cell-cell recognition(GO:0009988)
4.1 16.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
4.0 16.2 GO:0016572 histone phosphorylation(GO:0016572)
4.0 4.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
4.0 8.1 GO:0048311 mitochondrion distribution(GO:0048311)
4.0 84.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
4.0 32.2 GO:0042991 transcription factor import into nucleus(GO:0042991)
4.0 60.3 GO:0016575 histone deacetylation(GO:0016575)
4.0 12.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
4.0 16.0 GO:0043030 regulation of macrophage activation(GO:0043030)
4.0 4.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
4.0 15.9 GO:0043276 anoikis(GO:0043276)
4.0 43.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
4.0 4.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
3.9 3.9 GO:0046386 deoxyribose phosphate catabolic process(GO:0046386)
3.9 7.9 GO:0046909 intermembrane transport(GO:0046909)
3.9 7.8 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
3.9 78.3 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
3.9 7.8 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.9 23.4 GO:0006289 nucleotide-excision repair(GO:0006289)
3.9 7.8 GO:0042832 defense response to protozoan(GO:0042832)
3.9 27.2 GO:0000338 protein deneddylation(GO:0000338)
3.9 7.8 GO:0010829 negative regulation of glucose transport(GO:0010829)
3.9 7.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
3.9 27.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
3.9 30.9 GO:0043297 apical junction assembly(GO:0043297)
3.9 81.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
3.9 15.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
3.8 3.8 GO:0043482 endosome to melanosome transport(GO:0035646) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
3.8 11.5 GO:0006071 glycerol metabolic process(GO:0006071)
3.8 69.0 GO:0050982 detection of mechanical stimulus(GO:0050982)
3.8 49.7 GO:0008333 endosome to lysosome transport(GO:0008333)
3.8 38.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
3.8 7.6 GO:0042092 type 2 immune response(GO:0042092)
3.8 7.6 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
3.8 22.9 GO:0008053 mitochondrial fusion(GO:0008053)
3.8 11.4 GO:0060618 nipple development(GO:0060618)
3.8 15.2 GO:0001553 luteinization(GO:0001553)
3.8 41.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
3.8 15.2 GO:1904385 cellular response to angiotensin(GO:1904385) response to angiotensin(GO:1990776)
3.8 3.8 GO:1903887 motile primary cilium assembly(GO:1903887)
3.8 15.2 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
3.8 3.8 GO:0021764 amygdala development(GO:0021764)
3.8 71.7 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
3.8 165.8 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
3.8 7.5 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
3.7 3.7 GO:0014002 astrocyte development(GO:0014002)
3.7 11.2 GO:0016540 protein autoprocessing(GO:0016540)
3.7 7.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
3.7 22.4 GO:0014904 myotube cell development(GO:0014904)
3.7 52.1 GO:0006821 chloride transport(GO:0006821)
3.7 3.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
3.7 36.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
3.7 11.0 GO:0097320 membrane tubulation(GO:0097320)
3.6 7.3 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
3.6 3.6 GO:0070417 cellular response to cold(GO:0070417)
3.6 10.9 GO:0030325 adrenal gland development(GO:0030325)
3.6 21.8 GO:0035988 chondrocyte proliferation(GO:0035988)
3.6 14.5 GO:0007492 endoderm development(GO:0007492)
3.6 7.2 GO:0061157 mRNA destabilization(GO:0061157)
3.6 3.6 GO:0016064 immunoglobulin mediated immune response(GO:0016064)
3.6 195.2 GO:0006396 RNA processing(GO:0006396)
3.6 3.6 GO:0009584 detection of visible light(GO:0009584)
3.6 39.7 GO:0045727 positive regulation of translation(GO:0045727)
3.6 39.5 GO:0034505 tooth mineralization(GO:0034505)
3.6 7.2 GO:0048599 oocyte development(GO:0048599)
3.6 3.6 GO:0060416 response to growth hormone(GO:0060416)
3.6 7.2 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661)
3.6 3.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
3.6 14.2 GO:0051602 response to electrical stimulus(GO:0051602)
3.5 28.3 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
3.5 10.6 GO:0048659 smooth muscle cell proliferation(GO:0048659)
3.5 7.1 GO:0071773 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
3.5 10.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
3.5 3.5 GO:0015698 inorganic anion transport(GO:0015698)
3.5 28.2 GO:0048144 fibroblast proliferation(GO:0048144)
3.5 10.5 GO:0045760 positive regulation of action potential(GO:0045760)
3.5 28.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
3.5 14.0 GO:0045453 bone resorption(GO:0045453)
3.5 62.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
3.5 7.0 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
3.5 10.4 GO:0010470 regulation of gastrulation(GO:0010470)
3.5 27.8 GO:0001706 endoderm formation(GO:0001706)
3.5 27.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
3.5 3.5 GO:0046070 dGTP metabolic process(GO:0046070)
3.5 162.3 GO:0045444 fat cell differentiation(GO:0045444)
3.4 3.4 GO:0051591 response to cAMP(GO:0051591)
3.4 44.6 GO:0051865 protein autoubiquitination(GO:0051865)
3.4 3.4 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
3.4 82.4 GO:0006958 complement activation, classical pathway(GO:0006958)
3.4 13.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
3.4 13.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
3.4 27.2 GO:0007368 determination of left/right symmetry(GO:0007368)
3.4 10.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
3.4 13.6 GO:1901660 calcium ion export(GO:1901660)
3.4 6.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
3.4 16.9 GO:0000002 mitochondrial genome maintenance(GO:0000002)
3.4 30.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
3.4 134.7 GO:0006281 DNA repair(GO:0006281)
3.4 10.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.4 6.7 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
3.4 3.4 GO:0002092 positive regulation of receptor internalization(GO:0002092)
3.3 16.7 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
3.3 3.3 GO:0030431 sleep(GO:0030431)
3.3 16.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
3.3 23.4 GO:1990403 embryonic brain development(GO:1990403)
3.3 16.7 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
3.3 3.3 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
3.3 3.3 GO:0070384 Harderian gland development(GO:0070384)
3.3 3.3 GO:0042312 regulation of vasodilation(GO:0042312)
3.3 72.7 GO:0009408 response to heat(GO:0009408)
3.3 78.9 GO:0032543 mitochondrial translation(GO:0032543)
3.3 36.1 GO:0009411 response to UV(GO:0009411)
3.3 9.8 GO:1903232 melanosome assembly(GO:1903232)
3.3 3.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
3.3 6.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
3.3 3.3 GO:0046185 aldehyde catabolic process(GO:0046185)
3.3 29.3 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
3.3 19.5 GO:0070670 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
3.2 6.5 GO:0048255 mRNA stabilization(GO:0048255)
3.2 355.9 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
3.2 54.9 GO:0009060 aerobic respiration(GO:0009060)
3.2 9.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
3.2 12.9 GO:0007032 endosome organization(GO:0007032)
3.2 35.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
3.2 38.6 GO:0043627 response to estrogen(GO:0043627)
3.2 3.2 GO:1990001 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
3.2 3.2 GO:0050755 chemokine metabolic process(GO:0050755)
3.2 54.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
3.2 9.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
3.2 6.4 GO:0018210 peptidyl-threonine modification(GO:0018210)
3.2 9.5 GO:0060005 vestibular reflex(GO:0060005)
3.2 3.2 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028)
3.1 9.4 GO:0044458 motile cilium assembly(GO:0044458)
3.1 6.3 GO:0070831 basement membrane assembly(GO:0070831)
3.1 6.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
3.1 28.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
3.1 9.3 GO:0097435 fibril organization(GO:0097435)
3.1 34.2 GO:0044243 multicellular organism catabolic process(GO:0044243)
3.1 6.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
3.1 3.1 GO:0006553 lysine metabolic process(GO:0006553)
3.1 6.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
3.1 48.9 GO:0034728 nucleosome organization(GO:0034728)
3.1 3.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
3.0 3.0 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
3.0 12.1 GO:0015893 drug transport(GO:0015893)
3.0 9.1 GO:0048485 sympathetic nervous system development(GO:0048485)
3.0 9.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
3.0 12.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
3.0 48.2 GO:0007030 Golgi organization(GO:0007030)
3.0 21.1 GO:0016926 protein desumoylation(GO:0016926)
3.0 3.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
3.0 12.0 GO:0036159 inner dynein arm assembly(GO:0036159)
3.0 6.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
3.0 6.0 GO:0006399 tRNA metabolic process(GO:0006399)
3.0 116.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
3.0 3.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
3.0 11.9 GO:0006638 neutral lipid metabolic process(GO:0006638)
3.0 14.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
3.0 3.0 GO:0033687 osteoblast proliferation(GO:0033687)
3.0 3.0 GO:0043383 negative T cell selection(GO:0043383)
2.9 2.9 GO:0032098 regulation of appetite(GO:0032098)
2.9 2.9 GO:0097286 iron ion import(GO:0097286)
2.9 79.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
2.9 14.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
2.9 104.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
2.9 180.4 GO:0042060 wound healing(GO:0042060)
2.9 37.7 GO:0006749 glutathione metabolic process(GO:0006749)
2.9 8.7 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
2.9 210.4 GO:0006470 protein dephosphorylation(GO:0006470)
2.9 5.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
2.9 2.9 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
2.9 8.6 GO:0051642 centrosome localization(GO:0051642)
2.8 2.8 GO:0046148 pigment biosynthetic process(GO:0046148)
2.8 14.2 GO:0043968 histone H2A acetylation(GO:0043968)
2.8 2.8 GO:0042637 catagen(GO:0042637)
2.8 14.2 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
2.8 14.2 GO:0032620 interleukin-17 production(GO:0032620)
2.8 11.3 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
2.8 2.8 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
2.8 11.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
2.8 8.4 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
2.8 106.2 GO:0042254 ribosome biogenesis(GO:0042254)
2.8 2.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
2.8 8.4 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
2.8 30.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
2.8 8.3 GO:1901068 guanosine-containing compound metabolic process(GO:1901068)
2.8 5.5 GO:0060536 cartilage morphogenesis(GO:0060536)
2.8 5.5 GO:0006414 translational elongation(GO:0006414)
2.8 2.8 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
2.8 5.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
2.8 2.8 GO:0006591 ornithine metabolic process(GO:0006591)
2.8 5.5 GO:0003170 heart valve development(GO:0003170)
2.7 129.0 GO:0006457 protein folding(GO:0006457)
2.7 2.7 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
2.7 2.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
2.7 81.0 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
2.7 32.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
2.7 5.4 GO:0048251 elastic fiber assembly(GO:0048251)
2.7 2.7 GO:0015695 organic cation transport(GO:0015695)
2.7 79.7 GO:0019439 aromatic compound catabolic process(GO:0019439)
2.6 60.9 GO:0007519 skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
2.6 329.4 GO:0006412 translation(GO:0006412)
2.6 2.6 GO:0042402 cellular biogenic amine catabolic process(GO:0042402)
2.6 5.2 GO:0036514 dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
2.6 15.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
2.6 2.6 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
2.6 13.0 GO:0046548 retinal rod cell development(GO:0046548)
2.6 5.2 GO:0006527 arginine catabolic process(GO:0006527)
2.6 13.0 GO:0018344 protein geranylgeranylation(GO:0018344)
2.6 2.6 GO:0006543 glutamine catabolic process(GO:0006543)
2.6 5.2 GO:0002690 positive regulation of leukocyte chemotaxis(GO:0002690)
2.6 7.8 GO:0048266 behavioral response to pain(GO:0048266)
2.6 20.7 GO:0008272 sulfate transport(GO:0008272)
2.6 69.7 GO:0006006 glucose metabolic process(GO:0006006)
2.6 25.8 GO:0060325 face morphogenesis(GO:0060325)
2.6 10.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
2.6 5.1 GO:2000194 regulation of female gonad development(GO:2000194)
2.6 112.4 GO:0070647 protein modification by small protein conjugation or removal(GO:0070647)
2.5 5.1 GO:1903960 negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
2.5 7.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
2.5 35.5 GO:0006953 acute-phase response(GO:0006953)
2.5 32.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
2.5 7.5 GO:0009649 entrainment of circadian clock(GO:0009649)
2.5 5.0 GO:0042628 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
2.5 2.5 GO:0035092 sperm chromatin condensation(GO:0035092)
2.5 52.4 GO:0042493 response to drug(GO:0042493)
2.5 2.5 GO:1903998 regulation of eating behavior(GO:1903998)
2.5 2.5 GO:0060235 lens induction in camera-type eye(GO:0060235)
2.5 2.5 GO:0046834 lipid phosphorylation(GO:0046834)
2.5 4.9 GO:2000035 regulation of stem cell division(GO:2000035)
2.5 2.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
2.5 2.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
2.5 4.9 GO:0071467 cellular response to pH(GO:0071467)
2.5 2.5 GO:0006817 phosphate ion transport(GO:0006817)
2.4 4.9 GO:0018200 peptidyl-glutamic acid modification(GO:0018200)
2.4 2.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
2.4 2.4 GO:0045778 positive regulation of ossification(GO:0045778)
2.4 12.2 GO:0006825 copper ion transport(GO:0006825)
2.4 2.4 GO:0051385 response to mineralocorticoid(GO:0051385)
2.4 4.8 GO:0042891 antibiotic transport(GO:0042891)
2.4 4.8 GO:0051657 maintenance of organelle location(GO:0051657)
2.4 2.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.4 7.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
2.4 4.8 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
2.4 4.8 GO:0000060 protein import into nucleus, translocation(GO:0000060)
2.4 9.5 GO:0050435 beta-amyloid metabolic process(GO:0050435)
2.4 576.6 GO:0055114 oxidation-reduction process(GO:0055114)
2.4 2.4 GO:0002637 regulation of immunoglobulin production(GO:0002637)
2.4 9.4 GO:0009235 cobalamin metabolic process(GO:0009235)
2.4 14.1 GO:0031279 regulation of cyclase activity(GO:0031279)
2.4 11.8 GO:0061756 leukocyte adhesion to vascular endothelial cell(GO:0061756)
2.3 2.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
2.3 25.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
2.3 9.3 GO:0043029 T cell homeostasis(GO:0043029)
2.3 4.7 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
2.3 9.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
2.3 20.7 GO:0070229 negative regulation of lymphocyte apoptotic process(GO:0070229)
2.3 16.1 GO:1902017 regulation of cilium assembly(GO:1902017)
2.3 18.4 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
2.3 9.2 GO:0001967 suckling behavior(GO:0001967)
2.3 11.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
2.3 2.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.3 4.6 GO:0002121 inter-male aggressive behavior(GO:0002121)
2.3 4.5 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
2.3 4.5 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
2.3 4.5 GO:0090273 regulation of somatostatin secretion(GO:0090273)
2.3 2.3 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
2.3 2.3 GO:2001242 regulation of intrinsic apoptotic signaling pathway(GO:2001242)
2.2 2.2 GO:0046958 nonassociative learning(GO:0046958)
2.2 2.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
2.2 2.2 GO:0007412 axon target recognition(GO:0007412)
2.2 51.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
2.2 2.2 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
2.2 11.1 GO:0007127 meiosis I(GO:0007127)
2.2 2.2 GO:0002238 response to molecule of fungal origin(GO:0002238)
2.2 2.2 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
2.2 6.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
2.2 2.2 GO:0070633 transepithelial transport(GO:0070633)
2.2 2.2 GO:0048525 negative regulation of viral process(GO:0048525)
2.2 15.4 GO:0061512 protein localization to cilium(GO:0061512)
2.2 2.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
2.2 2.2 GO:0050798 activated T cell proliferation(GO:0050798)
2.2 17.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
2.2 8.6 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
2.1 6.4 GO:0032868 response to insulin(GO:0032868)
2.1 6.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
2.1 8.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
2.1 6.3 GO:0021984 adenohypophysis development(GO:0021984)
2.1 4.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
2.1 2.1 GO:0030252 growth hormone secretion(GO:0030252)
2.1 4.2 GO:0006265 DNA topological change(GO:0006265)
2.1 2.1 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
2.1 4.2 GO:0060259 regulation of feeding behavior(GO:0060259)
2.1 37.4 GO:0007059 chromosome segregation(GO:0007059)
2.1 2.1 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.1 4.1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
2.1 180.7 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
2.1 326.5 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
2.1 112.9 GO:0060271 cilium morphogenesis(GO:0060271)
2.1 18.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.0 2.0 GO:0034637 cellular carbohydrate biosynthetic process(GO:0034637)
2.0 18.3 GO:0045103 intermediate filament-based process(GO:0045103)
2.0 10.1 GO:0009615 response to virus(GO:0009615)
2.0 2.0 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
2.0 6.0 GO:0048733 sebaceous gland development(GO:0048733)
2.0 12.1 GO:0042278 purine nucleoside metabolic process(GO:0042278)
2.0 4.0 GO:0032350 regulation of hormone metabolic process(GO:0032350)
2.0 2.0 GO:0010155 regulation of proton transport(GO:0010155)
2.0 2.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
2.0 9.9 GO:0006884 cell volume homeostasis(GO:0006884)
2.0 2.0 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
2.0 5.9 GO:0006465 signal peptide processing(GO:0006465)
2.0 13.8 GO:0007631 feeding behavior(GO:0007631)
2.0 15.7 GO:0014850 response to muscle activity(GO:0014850)
2.0 3.9 GO:0050892 intestinal absorption(GO:0050892)
2.0 3.9 GO:0009404 toxin metabolic process(GO:0009404)
1.9 3.9 GO:0097480 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
1.9 19.5 GO:0007034 vacuolar transport(GO:0007034)
1.9 1.9 GO:0060856 establishment of blood-brain barrier(GO:0060856)
1.9 1.9 GO:0001951 intestinal D-glucose absorption(GO:0001951)
1.9 3.8 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.9 3.8 GO:0097284 hepatocyte apoptotic process(GO:0097284)
1.9 11.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
1.9 3.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
1.9 1.9 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
1.9 1.9 GO:0045924 regulation of female receptivity(GO:0045924)
1.8 1.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
1.8 49.5 GO:0071241 cellular response to inorganic substance(GO:0071241)
1.8 1.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
1.8 1.8 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.8 1.8 GO:0002931 response to ischemia(GO:0002931)
1.8 1.8 GO:0090313 regulation of protein targeting to membrane(GO:0090313)
1.8 1.8 GO:0045932 negative regulation of muscle contraction(GO:0045932)
1.8 5.3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
1.8 3.5 GO:0044843 cell cycle G1/S phase transition(GO:0044843)
1.8 5.3 GO:0032465 regulation of cytokinesis(GO:0032465)
1.7 73.2 GO:0016042 lipid catabolic process(GO:0016042)
1.7 5.2 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
1.7 1.7 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
1.7 43.0 GO:0006906 vesicle fusion(GO:0006906)
1.7 6.8 GO:0031638 zymogen activation(GO:0031638)
1.7 1.7 GO:0045933 positive regulation of muscle contraction(GO:0045933)
1.7 80.7 GO:0006816 calcium ion transport(GO:0006816)
1.7 31.9 GO:0031424 keratinization(GO:0031424)
1.7 1.7 GO:0001895 retina homeostasis(GO:0001895)
1.7 1.7 GO:0032370 positive regulation of lipid transport(GO:0032370)
1.7 15.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
1.7 1.7 GO:0035561 regulation of chromatin binding(GO:0035561)
1.7 3.3 GO:0060711 labyrinthine layer development(GO:0060711)
1.6 1.6 GO:0022613 ribonucleoprotein complex biogenesis(GO:0022613)
1.6 4.9 GO:0050701 interleukin-1 secretion(GO:0050701) interleukin-1 beta secretion(GO:0050702)
1.6 6.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
1.6 1.6 GO:0035878 nail development(GO:0035878)
1.6 1.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
1.6 21.1 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)
1.6 8.1 GO:0042159 protein depalmitoylation(GO:0002084) lipoprotein catabolic process(GO:0042159) macromolecule depalmitoylation(GO:0098734)
1.6 1.6 GO:0046324 regulation of glucose import(GO:0046324)
1.6 1.6 GO:2000021 regulation of ion homeostasis(GO:2000021)
1.6 1.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.6 3.2 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
1.6 3.2 GO:0051014 actin filament severing(GO:0051014)
1.6 7.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
1.6 4.7 GO:0050832 defense response to fungus(GO:0050832)
1.6 1.6 GO:0048102 autophagic cell death(GO:0048102)
1.6 73.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
1.5 12.2 GO:0016050 vesicle organization(GO:0016050)
1.5 21.3 GO:0048545 response to steroid hormone(GO:0048545)
1.5 14.9 GO:0019835 cytolysis(GO:0019835)
1.5 1.5 GO:0015670 carbon dioxide transport(GO:0015670)
1.5 1.5 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
1.5 7.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
1.5 20.4 GO:0006873 cellular ion homeostasis(GO:0006873)
1.5 4.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
1.4 1.4 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.4 5.8 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
1.4 35.9 GO:0072507 divalent inorganic cation homeostasis(GO:0072507)
1.4 10.0 GO:0009607 response to biotic stimulus(GO:0009607)
1.4 1.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.4 1.4 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.4 7.1 GO:0050821 protein stabilization(GO:0050821)
1.4 1.4 GO:0044117 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117)
1.4 92.7 GO:0042742 defense response to bacterium(GO:0042742)
1.4 2.8 GO:0097035 regulation of membrane lipid distribution(GO:0097035)
1.4 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
1.4 2.8 GO:0045931 positive regulation of mitotic cell cycle(GO:0045931)
1.4 1.4 GO:0055070 copper ion homeostasis(GO:0055070)
1.4 4.1 GO:0031581 hemidesmosome assembly(GO:0031581)
1.3 2.7 GO:0043043 peptide biosynthetic process(GO:0043043)
1.3 2.7 GO:0042481 regulation of odontogenesis(GO:0042481)
1.3 4.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
1.3 1.3 GO:0060017 parathyroid gland development(GO:0060017)
1.3 132.6 GO:0019236 response to pheromone(GO:0019236)
1.3 2.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.3 6.3 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
1.2 3.7 GO:0042157 lipoprotein metabolic process(GO:0042157)
1.2 7.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
1.2 7.4 GO:1901264 carbohydrate derivative transport(GO:1901264)
1.2 3.7 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin(GO:0003081)
1.2 1.2 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.2 1.2 GO:0005984 disaccharide metabolic process(GO:0005984)
1.2 1.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
1.2 1.2 GO:0051132 NK T cell activation(GO:0051132)
1.2 1289.7 GO:0007608 sensory perception of smell(GO:0007608)
1.2 1.2 GO:0002090 regulation of receptor internalization(GO:0002090)
1.1 5.7 GO:0030316 osteoclast differentiation(GO:0030316)
1.1 41.1 GO:0006954 inflammatory response(GO:0006954)
1.1 1.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
1.1 1.1 GO:0003161 cardiac conduction system development(GO:0003161)
1.1 2.3 GO:1904478 regulation of intestinal absorption(GO:1904478)
1.1 1.1 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
1.1 1.1 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
1.1 6.7 GO:0031214 biomineral tissue development(GO:0031214)
1.1 3.3 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
1.1 1.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.1 1.1 GO:0050957 equilibrioception(GO:0050957)
1.1 48.4 GO:0007601 visual perception(GO:0007601)
1.1 1.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
1.1 1.1 GO:0070231 T cell apoptotic process(GO:0070231)
1.1 1.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
1.1 2.1 GO:0044375 regulation of peroxisome size(GO:0044375)
1.0 1.0 GO:0002699 positive regulation of immune effector process(GO:0002699)
1.0 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
1.0 36.3 GO:0007605 sensory perception of sound(GO:0007605)
1.0 1.0 GO:0018094 protein polyglycylation(GO:0018094)
1.0 3.1 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
1.0 24.4 GO:0043086 negative regulation of catalytic activity(GO:0043086)
1.0 6.9 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
1.0 2.0 GO:0031647 regulation of protein stability(GO:0031647)
1.0 3.9 GO:0033344 cholesterol efflux(GO:0033344)
1.0 2.9 GO:0010469 regulation of receptor activity(GO:0010469)
1.0 1.0 GO:0032635 interleukin-6 production(GO:0032635)
1.0 1.9 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.9 0.9 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.9 0.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.9 1.8 GO:0033059 cellular pigmentation(GO:0033059)
0.9 1.8 GO:0008089 anterograde axonal transport(GO:0008089)
0.9 0.9 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.9 1.8 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.9 0.9 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.9 0.9 GO:0060525 prostate glandular acinus development(GO:0060525)
0.9 0.9 GO:0032094 response to food(GO:0032094)
0.9 0.9 GO:0002385 mucosal immune response(GO:0002385)
0.9 0.9 GO:0021782 glial cell development(GO:0021782)
0.9 0.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.8 1.7 GO:0002507 tolerance induction(GO:0002507)
0.8 3.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.8 28.9 GO:0006952 defense response(GO:0006952)
0.8 3.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.8 0.8 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.8 0.8 GO:1901655 cellular response to ketone(GO:1901655)
0.8 3.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.8 0.8 GO:0046683 response to organophosphorus(GO:0046683)
0.8 10.1 GO:0006959 humoral immune response(GO:0006959)
0.8 1.6 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.8 7.7 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.8 1.5 GO:0001757 somite specification(GO:0001757)
0.8 1.5 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.7 2.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.7 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.7 2.2 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.7 0.7 GO:0019321 pentose metabolic process(GO:0019321)
0.7 10.0 GO:0010629 negative regulation of gene expression(GO:0010629)
0.7 0.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.7 0.7 GO:0014015 positive regulation of gliogenesis(GO:0014015)
0.7 36.9 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.7 0.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.7 658.3 GO:0097659 nucleic acid-templated transcription(GO:0097659)
0.7 0.7 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.7 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.7 0.7 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.6 1.9 GO:0072337 modified amino acid transport(GO:0072337)
0.6 34.4 GO:0006897 endocytosis(GO:0006897)
0.6 0.6 GO:0014827 phasic smooth muscle contraction(GO:0014821) intestine smooth muscle contraction(GO:0014827)
0.6 0.6 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.6 0.6 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.6 3.0 GO:0044782 cilium organization(GO:0044782)
0.6 0.6 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.6 2.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.6 13.9 GO:0008643 carbohydrate transport(GO:0008643)
0.6 0.6 GO:0006091 generation of precursor metabolites and energy(GO:0006091)
0.6 0.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.6 1.1 GO:1903115 regulation of actin filament-based movement(GO:1903115)
0.6 3.3 GO:0051180 vitamin transport(GO:0051180)
0.5 8.5 GO:0070482 response to oxygen levels(GO:0070482)
0.5 1.0 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.5 105.7 GO:0006508 proteolysis(GO:0006508)
0.5 42.0 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.5 0.5 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.5 0.5 GO:0021511 spinal cord patterning(GO:0021511)
0.5 0.5 GO:0007616 long-term memory(GO:0007616)
0.4 4.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 61.4 GO:0055085 transmembrane transport(GO:0055085)
0.4 0.4 GO:0085029 extracellular matrix assembly(GO:0085029)
0.3 0.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 0.3 GO:0040029 regulation of gene expression, epigenetic(GO:0040029)
0.3 0.3 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.3 0.3 GO:0060443 mammary gland morphogenesis(GO:0060443)
0.3 3.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.3 0.3 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.3 0.3 GO:0008355 olfactory learning(GO:0008355)
0.2 0.2 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.2 0.2 GO:0032528 microvillus organization(GO:0032528)
0.2 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.2 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 0.2 GO:0006576 cellular biogenic amine metabolic process(GO:0006576)
0.1 0.3 GO:0006768 biotin metabolic process(GO:0006768)
0.1 6.9 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 0.9 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.1 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0072520 seminiferous tubule development(GO:0072520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
101.1 505.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
92.9 557.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
81.1 81.1 GO:0032587 ruffle membrane(GO:0032587)
71.3 213.8 GO:0046691 intracellular canaliculus(GO:0046691)
56.9 170.7 GO:0005833 hemoglobin complex(GO:0005833)
54.9 219.5 GO:1990130 Iml1 complex(GO:1990130)
45.9 275.5 GO:0000138 Golgi trans cisterna(GO:0000138)
40.4 121.3 GO:0097451 glial limiting end-foot(GO:0097451)
37.6 225.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
37.0 111.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
36.5 109.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
35.8 71.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
32.4 97.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
31.9 63.9 GO:0032127 dense core granule membrane(GO:0032127)
31.5 126.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
31.5 157.4 GO:0033093 Weibel-Palade body(GO:0033093)
29.7 89.2 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
29.7 118.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
29.5 177.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
29.4 235.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
28.7 287.4 GO:0097539 ciliary transition fiber(GO:0097539)
28.7 200.9 GO:0008290 F-actin capping protein complex(GO:0008290)
28.7 315.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
28.2 423.5 GO:0000421 autophagosome membrane(GO:0000421)
28.0 251.7 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
26.5 132.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
25.1 75.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
25.0 275.0 GO:0031143 pseudopodium(GO:0031143)
24.4 195.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
24.2 120.9 GO:0005828 kinetochore microtubule(GO:0005828)
23.9 95.6 GO:0033269 internode region of axon(GO:0033269)
23.4 140.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
22.5 67.6 GO:0005745 m-AAA complex(GO:0005745)
22.4 112.1 GO:0044326 dendritic spine neck(GO:0044326)
22.4 291.1 GO:0036038 MKS complex(GO:0036038)
22.4 178.8 GO:0005677 chromatin silencing complex(GO:0005677)
22.3 201.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
22.1 88.5 GO:0070545 PeBoW complex(GO:0070545)
22.0 66.0 GO:0097413 Lewy body(GO:0097413)
21.7 173.4 GO:0043203 axon hillock(GO:0043203)
21.5 64.4 GO:0030125 clathrin vesicle coat(GO:0030125)
21.3 127.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
21.2 1529.5 GO:0030863 cortical cytoskeleton(GO:0030863)
21.1 506.5 GO:0097228 sperm principal piece(GO:0097228)
20.4 81.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
20.3 81.4 GO:0031094 platelet dense tubular network(GO:0031094)
19.8 871.4 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
19.7 434.1 GO:0090544 BAF-type complex(GO:0090544)
19.7 78.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
19.5 97.7 GO:0005663 DNA replication factor C complex(GO:0005663)
19.5 78.1 GO:0035339 SPOTS complex(GO:0035339)
19.4 58.1 GO:0000811 GINS complex(GO:0000811)
19.3 58.0 GO:0031298 replication fork protection complex(GO:0031298)
19.3 57.9 GO:0032585 multivesicular body membrane(GO:0032585)
19.2 38.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
19.2 172.9 GO:0043020 NADPH oxidase complex(GO:0043020)
19.0 57.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
18.8 18.8 GO:0097422 tubular endosome(GO:0097422)
18.7 168.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)
18.6 464.3 GO:0008305 integrin complex(GO:0008305)
18.5 129.3 GO:0032591 dendritic spine membrane(GO:0032591)
18.2 91.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
18.2 401.0 GO:0031941 filamentous actin(GO:0031941)
18.1 54.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
18.1 54.3 GO:0036449 microtubule minus-end(GO:0036449)
17.9 89.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
17.8 106.9 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
17.8 177.8 GO:0031080 nuclear pore outer ring(GO:0031080)
17.7 300.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
17.6 335.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
17.6 52.9 GO:0071437 invadopodium(GO:0071437)
17.5 17.5 GO:0005903 brush border(GO:0005903)
17.4 52.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
16.9 16.9 GO:0034709 methylosome(GO:0034709)
16.8 50.5 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
16.8 50.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
16.8 385.5 GO:0030131 clathrin adaptor complex(GO:0030131)
16.4 65.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
16.4 16.4 GO:1990423 RZZ complex(GO:1990423)
16.3 32.6 GO:0031088 platelet dense granule membrane(GO:0031088)
16.1 145.0 GO:0005869 dynactin complex(GO:0005869)
16.0 256.4 GO:0000145 exocyst(GO:0000145)
15.9 366.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
15.9 79.4 GO:0005827 polar microtubule(GO:0005827)
15.9 79.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
15.7 110.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
15.7 220.1 GO:0097440 apical dendrite(GO:0097440)
15.6 62.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
15.5 31.0 GO:0089701 U2AF(GO:0089701)
15.5 123.9 GO:0044666 MLL3/4 complex(GO:0044666)
15.4 138.8 GO:0031010 ISWI-type complex(GO:0031010)
15.2 15.2 GO:0031523 Myb complex(GO:0031523)
15.2 15.2 GO:0097149 centralspindlin complex(GO:0097149)
15.1 136.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
15.1 30.1 GO:0044316 cone cell pedicle(GO:0044316)
15.0 150.1 GO:0008278 cohesin complex(GO:0008278)
15.0 45.0 GO:0005588 collagen type V trimer(GO:0005588)
15.0 59.8 GO:0002079 inner acrosomal membrane(GO:0002079)
15.0 59.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
14.8 133.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
14.7 14.7 GO:0097450 astrocyte end-foot(GO:0097450)
14.6 102.0 GO:0000788 nuclear nucleosome(GO:0000788)
14.5 43.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
14.5 58.1 GO:0044530 supraspliceosomal complex(GO:0044530)
14.5 43.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
14.4 14.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
14.2 71.2 GO:0043198 dendritic shaft(GO:0043198)
14.2 28.5 GO:0070939 Dsl1p complex(GO:0070939)
14.2 42.5 GO:0005899 insulin receptor complex(GO:0005899)
14.1 28.2 GO:0097542 ciliary tip(GO:0097542)
14.0 98.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
14.0 42.0 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
13.8 800.3 GO:0005795 Golgi stack(GO:0005795)
13.7 54.7 GO:0071141 SMAD protein complex(GO:0071141)
13.6 40.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
13.6 40.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
13.6 40.7 GO:1990923 PET complex(GO:1990923)
13.6 230.6 GO:0001673 male germ cell nucleus(GO:0001673)
13.5 108.3 GO:0030314 junctional membrane complex(GO:0030314)
13.4 53.7 GO:0002142 stereocilia ankle link complex(GO:0002142)
13.4 67.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
13.4 174.5 GO:0034704 calcium channel complex(GO:0034704)
13.4 147.1 GO:0005652 nuclear lamina(GO:0005652)
13.3 53.3 GO:0097524 sperm plasma membrane(GO:0097524)
13.2 79.2 GO:0071986 Ragulator complex(GO:0071986)
13.1 92.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
13.1 52.4 GO:0071439 clathrin complex(GO:0071439)
13.1 39.3 GO:1990462 omegasome(GO:1990462)
13.0 52.0 GO:0043073 germ cell nucleus(GO:0043073)
13.0 91.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
12.9 90.6 GO:0031931 TORC1 complex(GO:0031931)
12.8 89.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
12.8 64.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
12.8 127.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
12.7 12.7 GO:0042827 platelet dense granule(GO:0042827)
12.7 50.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
12.7 76.1 GO:0031415 NatA complex(GO:0031415)
12.7 721.2 GO:0000118 histone deacetylase complex(GO:0000118)
12.6 529.7 GO:0017053 transcriptional repressor complex(GO:0017053)
12.5 311.5 GO:0005771 multivesicular body(GO:0005771)
12.3 98.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
12.2 440.3 GO:0005905 clathrin-coated pit(GO:0005905)
12.2 36.7 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
12.2 219.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
12.2 133.8 GO:0031528 microvillus membrane(GO:0031528)
12.1 398.3 GO:0016592 mediator complex(GO:0016592)
12.0 83.9 GO:0042382 paraspeckles(GO:0042382)
12.0 24.0 GO:0044327 dendritic spine head(GO:0044327)
11.9 23.9 GO:0031595 nuclear proteasome complex(GO:0031595)
11.9 143.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
11.9 107.4 GO:0002116 semaphorin receptor complex(GO:0002116)
11.9 35.6 GO:0005914 spot adherens junction(GO:0005914)
11.8 59.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
11.8 129.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
11.7 23.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
11.7 35.0 GO:0016939 kinesin II complex(GO:0016939)
11.7 81.7 GO:0008385 IkappaB kinase complex(GO:0008385)
11.6 93.0 GO:0008180 COP9 signalosome(GO:0008180)
11.6 34.7 GO:0044611 nuclear pore inner ring(GO:0044611)
11.6 57.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
11.6 138.7 GO:0042581 specific granule(GO:0042581)
11.5 276.2 GO:0055038 recycling endosome membrane(GO:0055038)
11.5 115.1 GO:0046581 intercellular canaliculus(GO:0046581)
11.5 11.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
11.5 22.9 GO:0032133 chromosome passenger complex(GO:0032133)
11.4 125.4 GO:0044292 dendrite terminus(GO:0044292)
11.4 11.4 GO:0097418 neurofibrillary tangle(GO:0097418)
11.4 34.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
11.3 260.4 GO:0005776 autophagosome(GO:0005776)
11.3 45.2 GO:1990909 Wnt signalosome(GO:1990909)
11.3 33.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
11.2 11.2 GO:0097208 alveolar lamellar body(GO:0097208)
11.2 22.4 GO:0032584 growth cone membrane(GO:0032584)
11.2 55.9 GO:0035859 Seh1-associated complex(GO:0035859)
11.2 100.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
11.2 11.2 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
11.1 33.4 GO:0019815 B cell receptor complex(GO:0019815)
11.1 475.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
11.0 11.0 GO:0045178 basal part of cell(GO:0045178)
11.0 131.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
11.0 131.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
11.0 109.9 GO:0042405 nuclear inclusion body(GO:0042405)
10.9 10.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
10.9 10.9 GO:0043219 lateral loop(GO:0043219)
10.9 76.1 GO:0033263 CORVET complex(GO:0033263)
10.8 32.5 GO:0001650 fibrillar center(GO:0001650)
10.8 216.2 GO:0005680 anaphase-promoting complex(GO:0005680)
10.8 172.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
10.7 10.7 GO:0030137 COPI-coated vesicle(GO:0030137)
10.7 21.4 GO:0005642 annulate lamellae(GO:0005642)
10.6 10.6 GO:0032444 activin responsive factor complex(GO:0032444)
10.6 42.4 GO:0001651 dense fibrillar component(GO:0001651)
10.6 180.0 GO:0000242 pericentriolar material(GO:0000242)
10.6 105.7 GO:0016235 aggresome(GO:0016235)
10.6 337.8 GO:0008023 transcription elongation factor complex(GO:0008023)
10.4 83.1 GO:0031091 platelet alpha granule(GO:0031091)
10.4 41.5 GO:0030127 COPII vesicle coat(GO:0030127)
10.4 72.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
10.3 20.7 GO:1990597 AIP1-IRE1 complex(GO:1990597)
10.3 41.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
10.3 113.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
10.3 185.2 GO:0030904 retromer complex(GO:0030904)
10.3 41.1 GO:0001917 photoreceptor inner segment(GO:0001917)
10.2 71.7 GO:0097431 mitotic spindle pole(GO:0097431)
10.2 10.2 GO:0033270 paranode region of axon(GO:0033270)
10.2 20.3 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
10.1 30.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
10.1 241.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
10.1 20.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
10.1 502.9 GO:0042641 actomyosin(GO:0042641)
10.0 421.2 GO:0016363 nuclear matrix(GO:0016363)
10.0 30.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
9.9 169.0 GO:0034451 centriolar satellite(GO:0034451)
9.9 128.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
9.8 39.3 GO:0097452 GAIT complex(GO:0097452)
9.8 88.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
9.8 540.0 GO:0016605 PML body(GO:0016605)
9.8 48.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
9.8 303.1 GO:0098791 Golgi subcompartment(GO:0098791)
9.7 58.3 GO:0030894 replisome(GO:0030894)
9.6 77.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
9.6 38.5 GO:0005927 muscle tendon junction(GO:0005927)
9.6 19.2 GO:0000791 euchromatin(GO:0000791)
9.6 9.6 GO:0070761 pre-snoRNP complex(GO:0070761)
9.6 641.5 GO:1990204 oxidoreductase complex(GO:1990204)
9.6 105.2 GO:0002102 podosome(GO:0002102)
9.5 56.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
9.4 28.3 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
9.4 75.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
9.4 28.1 GO:0044232 organelle membrane contact site(GO:0044232)
9.3 56.0 GO:0017119 Golgi transport complex(GO:0017119)
9.3 503.6 GO:0000502 proteasome complex(GO:0000502)
9.3 27.9 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
9.3 27.8 GO:0032279 asymmetric synapse(GO:0032279)
9.3 120.6 GO:0010369 chromocenter(GO:0010369)
9.3 27.8 GO:0031430 M band(GO:0031430)
9.3 333.3 GO:0005643 nuclear pore(GO:0005643)
9.2 92.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
9.2 82.9 GO:0000813 ESCRT I complex(GO:0000813)
9.1 200.7 GO:0001772 immunological synapse(GO:0001772)
9.1 27.4 GO:0042583 chromaffin granule(GO:0042583)
9.0 903.9 GO:0000775 chromosome, centromeric region(GO:0000775)
9.0 45.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
9.0 234.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
9.0 45.0 GO:0045098 type III intermediate filament(GO:0045098)
9.0 62.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
9.0 44.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
9.0 18.0 GO:0030870 Mre11 complex(GO:0030870)
9.0 71.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
9.0 26.9 GO:0000346 transcription export complex(GO:0000346)
8.9 26.8 GO:0005955 calcineurin complex(GO:0005955)
8.9 8.9 GO:0036488 CHOP-C/EBP complex(GO:0036488)
8.9 124.1 GO:0043205 fibril(GO:0043205)
8.8 70.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
8.8 79.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
8.8 35.1 GO:0000796 condensin complex(GO:0000796)
8.7 96.1 GO:0032039 integrator complex(GO:0032039)
8.7 8.7 GO:0042788 polysomal ribosome(GO:0042788)
8.7 26.0 GO:0097443 sorting endosome(GO:0097443)
8.6 102.7 GO:0005876 spindle microtubule(GO:0005876)
8.5 68.3 GO:0070652 HAUS complex(GO:0070652)
8.5 8.5 GO:0097470 ribbon synapse(GO:0097470)
8.5 25.5 GO:0070938 contractile ring(GO:0070938)
8.5 25.5 GO:0000805 X chromosome(GO:0000805)
8.5 50.9 GO:0034464 BBSome(GO:0034464)
8.5 110.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
8.5 25.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
8.5 2258.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
8.5 42.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
8.4 405.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
8.4 59.0 GO:0031090 organelle membrane(GO:0031090)
8.4 58.9 GO:0060091 kinocilium(GO:0060091)
8.4 16.8 GO:0097543 ciliary inversin compartment(GO:0097543)
8.4 16.8 GO:0001739 sex chromatin(GO:0001739)
8.3 191.9 GO:0055037 recycling endosome(GO:0055037)
8.3 83.2 GO:0031011 Ino80 complex(GO:0031011)
8.3 66.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
8.3 74.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
8.3 91.0 GO:0030914 STAGA complex(GO:0030914)
8.2 99.0 GO:0035869 ciliary transition zone(GO:0035869)
8.2 49.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
8.2 32.9 GO:0001891 phagocytic cup(GO:0001891)
8.2 1010.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
8.2 16.4 GO:0031594 neuromuscular junction(GO:0031594)
8.2 90.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
8.2 146.9 GO:0035145 exon-exon junction complex(GO:0035145)
8.1 16.2 GO:0097512 cardiac myofibril(GO:0097512)
8.1 24.2 GO:0000974 Prp19 complex(GO:0000974)
8.1 16.1 GO:0043218 compact myelin(GO:0043218)
8.0 176.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
8.0 16.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
8.0 88.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
8.0 16.0 GO:0044309 neuron spine(GO:0044309)
7.9 71.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
7.9 23.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
7.9 79.3 GO:0071004 U2-type prespliceosome(GO:0071004)
7.9 8618.4 GO:0005829 cytosol(GO:0005829)
7.9 182.0 GO:0012505 endomembrane system(GO:0012505)
7.8 15.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
7.8 195.2 GO:0031201 SNARE complex(GO:0031201)
7.8 62.2 GO:0033391 chromatoid body(GO:0033391)
7.7 15.5 GO:0005687 U4 snRNP(GO:0005687)
7.7 77.3 GO:0044815 DNA packaging complex(GO:0044815)
7.7 15.4 GO:0033268 node of Ranvier(GO:0033268)
7.7 15.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
7.6 7.6 GO:0005686 U2 snRNP(GO:0005686)
7.6 114.5 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
7.6 15.2 GO:0030056 hemidesmosome(GO:0030056)
7.6 30.5 GO:0031932 TORC2 complex(GO:0031932)
7.6 30.4 GO:1990745 EARP complex(GO:1990745)
7.6 22.8 GO:0000781 chromosome, telomeric region(GO:0000781)
7.6 30.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
7.5 52.5 GO:0000124 SAGA complex(GO:0000124)
7.5 67.4 GO:0002080 acrosomal membrane(GO:0002080)
7.5 7.5 GO:0071010 prespliceosome(GO:0071010)
7.4 22.3 GO:0005577 fibrinogen complex(GO:0005577)
7.4 14.8 GO:0071011 precatalytic spliceosome(GO:0071011)
7.4 296.2 GO:0000793 condensed chromosome(GO:0000793)
7.4 96.0 GO:0030014 CCR4-NOT complex(GO:0030014)
7.4 14.7 GO:0097255 R2TP complex(GO:0097255)
7.3 14.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
7.3 14.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
7.3 58.0 GO:0045335 phagocytic vesicle(GO:0045335)
7.2 14.5 GO:0051233 spindle midzone(GO:0051233)
7.2 144.3 GO:0031519 PcG protein complex(GO:0031519)
7.1 56.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
7.1 14.2 GO:0070469 respiratory chain(GO:0070469)
7.1 28.4 GO:0016600 flotillin complex(GO:0016600)
7.1 262.3 GO:0016459 myosin complex(GO:0016459)
7.1 77.8 GO:0035861 site of double-strand break(GO:0035861)
7.1 21.2 GO:0071001 U4/U6 snRNP(GO:0071001)
7.1 28.3 GO:0035631 CD40 receptor complex(GO:0035631)
7.0 337.4 GO:0044440 endosomal part(GO:0044440)
7.0 7.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
7.0 13.9 GO:0032389 MutLalpha complex(GO:0032389)
6.9 145.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
6.9 7399.9 GO:0005654 nucleoplasm(GO:0005654)
6.9 13.8 GO:0098536 deuterosome(GO:0098536)
6.9 20.7 GO:0031501 mannosyltransferase complex(GO:0031501)
6.9 178.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
6.9 479.8 GO:0072562 blood microparticle(GO:0072562)
6.8 40.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
6.8 40.8 GO:0030880 RNA polymerase complex(GO:0030880)
6.8 27.2 GO:0005796 Golgi lumen(GO:0005796)
6.7 13.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
6.7 20.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
6.6 1574.6 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
6.6 39.5 GO:0031616 spindle pole centrosome(GO:0031616)
6.5 418.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
6.5 632.1 GO:0005759 mitochondrial matrix(GO:0005759)
6.5 103.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
6.5 45.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
6.4 530.6 GO:0000139 Golgi membrane(GO:0000139)
6.4 370.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
6.4 6.4 GO:0043209 myelin sheath(GO:0043209)
6.3 38.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
6.3 12.6 GO:0030689 Noc complex(GO:0030689)
6.3 200.2 GO:0019898 extrinsic component of membrane(GO:0019898)
6.2 3811.5 GO:0005739 mitochondrion(GO:0005739)
6.2 6.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
6.2 24.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
6.1 18.4 GO:0042627 chylomicron(GO:0042627)
6.0 281.7 GO:0008021 synaptic vesicle(GO:0008021)
5.9 113.0 GO:0005811 lipid particle(GO:0005811)
5.9 17.8 GO:0031417 NatC complex(GO:0031417)
5.9 29.4 GO:0045120 pronucleus(GO:0045120)
5.9 29.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
5.8 993.6 GO:0005768 endosome(GO:0005768)
5.8 115.1 GO:0030133 transport vesicle(GO:0030133)
5.6 73.0 GO:0030992 intraciliary transport particle B(GO:0030992)
5.6 55.8 GO:0043034 costamere(GO:0043034)
5.5 27.7 GO:0031512 motile primary cilium(GO:0031512)
5.5 11.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
5.5 569.3 GO:0031975 envelope(GO:0031975)
5.5 27.5 GO:0030057 desmosome(GO:0030057)
5.5 5.5 GO:0070603 SWI/SNF superfamily-type complex(GO:0070603) INO80-type complex(GO:0097346)
5.5 32.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
5.5 16.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
5.5 480.5 GO:0016323 basolateral plasma membrane(GO:0016323)
5.5 158.2 GO:0016328 lateral plasma membrane(GO:0016328)
5.4 147.1 GO:0034707 chloride channel complex(GO:0034707)
5.4 140.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
5.4 475.7 GO:1990234 transferase complex(GO:1990234)
5.3 5.3 GO:0031258 lamellipodium membrane(GO:0031258)
5.3 10.5 GO:0001520 outer dense fiber(GO:0001520)
5.2 5.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
5.2 1491.6 GO:0005794 Golgi apparatus(GO:0005794)
5.1 81.8 GO:0005913 cell-cell adherens junction(GO:0005913)
5.1 71.3 GO:0044853 plasma membrane raft(GO:0044853)
5.1 15.3 GO:0042612 MHC class I protein complex(GO:0042612)
5.0 59.9 GO:0001750 photoreceptor outer segment(GO:0001750)
5.0 24.9 GO:0032426 stereocilium tip(GO:0032426)
4.9 819.6 GO:0098552 side of membrane(GO:0098552)
4.9 9.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
4.9 3058.4 GO:0005783 endoplasmic reticulum(GO:0005783)
4.9 111.7 GO:0042383 sarcolemma(GO:0042383)
4.8 92.0 GO:0005929 cilium(GO:0005929)
4.8 435.3 GO:0005667 transcription factor complex(GO:0005667)
4.8 4.8 GO:0005726 perichromatin fibrils(GO:0005726)
4.8 4.8 GO:0000439 core TFIIH complex(GO:0000439)
4.8 47.6 GO:0043234 protein complex(GO:0043234)
4.8 14.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
4.7 4.7 GO:0001652 granular component(GO:0001652)
4.6 55.6 GO:0005844 polysome(GO:0005844)
4.6 9.3 GO:0005840 ribosome(GO:0005840)
4.6 4.6 GO:0044299 C-fiber(GO:0044299)
4.6 41.3 GO:0015629 actin cytoskeleton(GO:0015629)
4.5 2531.7 GO:0031982 vesicle(GO:0031982)
4.5 107.6 GO:0000228 nuclear chromosome(GO:0000228)
4.5 53.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
4.5 476.9 GO:0005874 microtubule(GO:0005874)
4.3 4.3 GO:0016528 sarcoplasm(GO:0016528)
4.2 63.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
4.2 223.9 GO:0031225 anchored component of membrane(GO:0031225)
4.2 4.2 GO:0032155 cell division site(GO:0032153) cell division site part(GO:0032155)
4.1 4.1 GO:0005875 microtubule associated complex(GO:0005875)
4.1 53.2 GO:0000922 spindle pole(GO:0000922)
4.0 9430.4 GO:0005737 cytoplasm(GO:0005737)
4.0 32.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
3.9 3.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
3.7 3.7 GO:0032993 protein-DNA complex(GO:0032993)
3.7 7.4 GO:0097225 sperm midpiece(GO:0097225)
3.6 21.8 GO:0043204 perikaryon(GO:0043204)
3.6 3.6 GO:0044297 cell body(GO:0044297)
3.6 18.0 GO:0097223 sperm part(GO:0097223)
3.4 44.1 GO:0098793 presynapse(GO:0098793)
3.4 10.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
3.3 9.9 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
3.3 6.5 GO:0042555 MCM complex(GO:0042555)
3.3 74.9 GO:0016324 apical plasma membrane(GO:0016324)
3.2 413.3 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
3.2 6.3 GO:1902494 catalytic complex(GO:1902494)
3.2 22.1 GO:1902555 endoribonuclease complex(GO:1902555)
3.1 40.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
3.1 65.0 GO:0005694 chromosome(GO:0005694)
3.0 3208.3 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
2.9 5.9 GO:0032420 stereocilium(GO:0032420)
2.9 327.3 GO:0009986 cell surface(GO:0009986)
2.9 2255.0 GO:0005576 extracellular region(GO:0005576)
2.8 39.8 GO:0005922 connexon complex(GO:0005922)
2.8 3025.6 GO:0005886 plasma membrane(GO:0005886)
2.6 4098.8 GO:0016020 membrane(GO:0016020)
2.4 259.8 GO:0005622 intracellular(GO:0005622)
1.8 9.2 GO:0097458 neuron part(GO:0097458)
1.8 25.2 GO:0005623 cell(GO:0005623)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
126.0 504.1 GO:0031720 haptoglobin binding(GO:0031720)
94.0 376.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
85.3 597.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
81.7 81.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
81.1 243.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
80.7 322.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
79.7 318.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
79.2 237.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
65.5 196.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
62.5 250.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
61.3 245.2 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
56.0 112.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
55.7 389.7 GO:0019957 C-C chemokine binding(GO:0019957)
54.7 273.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
53.0 159.1 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
52.5 157.6 GO:0030350 iron-responsive element binding(GO:0030350)
50.8 152.3 GO:0004064 arylesterase activity(GO:0004064)
48.4 145.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
48.2 144.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
47.8 143.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
47.2 188.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
47.1 188.6 GO:0009374 biotin binding(GO:0009374)
43.0 258.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
42.7 128.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
42.0 839.2 GO:0030506 ankyrin binding(GO:0030506)
41.7 125.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
41.3 41.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
40.7 81.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
40.6 324.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
40.2 160.8 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
39.3 274.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
38.6 154.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
38.4 38.4 GO:1990459 transferrin receptor binding(GO:1990459)
38.0 190.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
37.7 113.1 GO:0070644 vitamin D response element binding(GO:0070644)
37.2 334.9 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
36.9 147.5 GO:0004127 cytidylate kinase activity(GO:0004127)
36.6 292.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
35.7 71.4 GO:1901612 cardiolipin binding(GO:1901612)
35.5 71.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
34.6 242.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
34.2 171.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
33.9 33.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
33.6 100.8 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
33.4 100.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
33.3 166.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
33.3 199.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
33.1 99.3 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
33.1 132.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
32.1 192.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
32.0 64.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
32.0 159.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
31.8 95.3 GO:0001069 regulatory region RNA binding(GO:0001069)
31.6 63.2 GO:0070412 R-SMAD binding(GO:0070412)
31.1 249.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
30.9 92.7 GO:0031711 bradykinin receptor binding(GO:0031711)
30.2 90.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
30.0 360.5 GO:0016208 AMP binding(GO:0016208)
29.8 89.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
29.6 177.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
28.9 231.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
28.6 28.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
28.5 56.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
28.2 84.7 GO:0019961 interferon binding(GO:0019961)
28.2 56.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
28.1 56.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
27.5 109.9 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
27.3 354.8 GO:0070300 phosphatidic acid binding(GO:0070300)
27.1 108.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
26.8 134.2 GO:0005131 growth hormone receptor binding(GO:0005131)
26.8 214.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
26.4 26.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
26.2 78.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
26.2 340.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
26.1 78.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
25.7 51.3 GO:0051920 peroxiredoxin activity(GO:0051920)
25.2 176.2 GO:0016803 ether hydrolase activity(GO:0016803)
25.1 150.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
25.0 50.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
24.8 74.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
24.6 221.6 GO:0016004 phospholipase activator activity(GO:0016004)
24.6 836.7 GO:0016831 carboxy-lyase activity(GO:0016831)
24.2 24.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
24.2 72.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
24.2 145.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
24.1 120.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
24.1 72.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
23.6 70.8 GO:2001070 starch binding(GO:2001070)
23.6 188.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
23.6 70.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
23.5 211.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
23.5 164.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
23.4 23.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
23.3 209.9 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
23.3 93.2 GO:0005047 signal recognition particle binding(GO:0005047)
23.3 93.0 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
23.2 208.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
22.9 45.8 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
22.9 205.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
22.8 68.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
22.6 67.7 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
22.3 111.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
22.1 88.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
22.0 44.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
22.0 66.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
22.0 65.9 GO:0051425 PTB domain binding(GO:0051425)
21.7 282.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
21.6 64.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
21.6 64.8 GO:0019887 protein kinase regulator activity(GO:0019887)
21.6 86.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
21.3 21.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
21.2 84.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
21.1 147.7 GO:0046790 virion binding(GO:0046790)
21.0 63.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
21.0 63.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
20.8 62.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
20.7 82.8 GO:0004849 uridine kinase activity(GO:0004849)
20.7 82.7 GO:0070051 fibrinogen binding(GO:0070051)
20.5 61.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
20.3 61.0 GO:0008422 beta-glucosidase activity(GO:0008422)
20.1 100.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
20.0 80.2 GO:0015057 thrombin receptor activity(GO:0015057)
20.0 99.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
19.9 79.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
19.9 297.8 GO:0005521 lamin binding(GO:0005521)
19.8 39.7 GO:0004096 catalase activity(GO:0004096)
19.8 79.2 GO:0043559 insulin binding(GO:0043559)
19.8 39.6 GO:0016419 S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
19.5 78.2 GO:0005344 oxygen transporter activity(GO:0005344)
19.4 19.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
19.3 57.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
19.2 77.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
19.2 172.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
19.0 56.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
18.9 56.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
18.6 540.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
18.5 203.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
18.5 55.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
18.5 73.9 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
18.4 36.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
18.3 36.6 GO:0016842 amidine-lyase activity(GO:0016842)
18.2 54.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
18.1 72.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
17.9 322.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
17.9 53.6 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
17.9 428.5 GO:0045502 dynein binding(GO:0045502)
17.8 267.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
17.8 53.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
17.8 266.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
17.7 53.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
17.7 88.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
17.7 70.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
17.7 35.3 GO:0002060 purine nucleobase binding(GO:0002060)
17.6 176.0 GO:0019206 nucleoside kinase activity(GO:0019206)
17.6 87.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
17.6 70.2 GO:0050693 LBD domain binding(GO:0050693)
17.5 35.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
17.5 87.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
17.4 364.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
17.3 414.3 GO:0030507 spectrin binding(GO:0030507)
17.2 137.8 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
17.1 68.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
17.1 51.3 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
17.1 51.2 GO:0004104 cholinesterase activity(GO:0004104)
17.0 119.3 GO:0018638 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
17.0 118.9 GO:0070567 cytidylyltransferase activity(GO:0070567)
16.9 101.7 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
16.9 16.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
16.8 67.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
16.8 50.5 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
16.8 50.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
16.8 268.4 GO:0070064 proline-rich region binding(GO:0070064)
16.7 50.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
16.4 32.9 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
16.3 456.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
16.3 341.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
16.2 48.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
16.1 128.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
16.1 144.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
15.9 95.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
15.9 15.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
15.8 79.0 GO:0070324 thyroid hormone binding(GO:0070324)
15.8 110.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
15.8 63.1 GO:0015232 heme transporter activity(GO:0015232)
15.6 78.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
15.6 46.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
15.6 93.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
15.5 15.5 GO:0033142 progesterone receptor binding(GO:0033142)
15.4 46.3 GO:0004771 sterol esterase activity(GO:0004771)
15.4 138.7 GO:0008301 DNA binding, bending(GO:0008301)
15.4 138.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
15.3 91.8 GO:0001727 lipid kinase activity(GO:0001727)
15.3 45.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
15.2 121.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
15.2 45.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
15.1 60.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
15.1 136.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
15.1 120.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
15.0 45.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
15.0 194.8 GO:0010181 FMN binding(GO:0010181)
15.0 15.0 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
14.9 89.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
14.9 44.6 GO:0042296 ISG15 transferase activity(GO:0042296)
14.8 147.7 GO:0051010 microtubule plus-end binding(GO:0051010)
14.7 58.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
14.7 14.7 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
14.5 58.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
14.5 43.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
14.5 159.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
14.5 87.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
14.5 57.9 GO:0038100 nodal binding(GO:0038100)
14.4 173.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
14.4 43.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
14.4 100.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
14.2 71.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
14.2 71.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
14.2 42.5 GO:0035174 histone serine kinase activity(GO:0035174)
14.2 14.2 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
14.2 155.7 GO:0004407 histone deacetylase activity(GO:0004407)
14.1 14.1 GO:0032452 histone demethylase activity(GO:0032452)
14.1 254.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
14.1 42.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
14.1 155.0 GO:0042162 telomeric DNA binding(GO:0042162)
14.1 42.2 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
14.0 14.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
14.0 42.0 GO:0030984 kininogen binding(GO:0030984)
14.0 265.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
13.9 41.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
13.8 55.3 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
13.8 69.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
13.8 55.3 GO:1990932 5.8S rRNA binding(GO:1990932)
13.8 55.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
13.8 41.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
13.8 151.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
13.7 68.7 GO:0016151 nickel cation binding(GO:0016151)
13.7 54.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
13.7 68.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
13.6 422.4 GO:0048487 beta-tubulin binding(GO:0048487)
13.6 245.0 GO:0008483 transaminase activity(GO:0008483)
13.5 54.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
13.5 13.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
13.5 54.0 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
13.5 53.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
13.5 53.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
13.4 40.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
13.4 66.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
13.4 53.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
13.2 238.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
13.2 39.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
13.1 552.3 GO:0043022 ribosome binding(GO:0043022)
13.1 39.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
13.1 183.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
13.1 157.0 GO:0070628 proteasome binding(GO:0070628)
13.0 129.5 GO:0004568 chitinase activity(GO:0004568)
12.9 77.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
12.9 12.9 GO:0051434 BH3 domain binding(GO:0051434)
12.9 25.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
12.9 51.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
12.8 64.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
12.8 25.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
12.8 102.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
12.8 242.8 GO:0003746 translation elongation factor activity(GO:0003746)
12.8 191.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
12.6 341.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
12.6 366.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
12.6 25.2 GO:1990239 steroid hormone binding(GO:1990239)
12.6 62.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
12.6 364.7 GO:0050699 WW domain binding(GO:0050699)
12.6 25.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
12.5 125.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
12.5 25.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
12.5 112.5 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
12.4 124.4 GO:0001618 virus receptor activity(GO:0001618)
12.4 272.8 GO:0050681 androgen receptor binding(GO:0050681)
12.4 136.2 GO:0030955 potassium ion binding(GO:0030955)
12.4 49.5 GO:0004594 pantothenate kinase activity(GO:0004594)
12.4 61.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
12.3 49.4 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
12.3 37.0 GO:1990460 leptin receptor binding(GO:1990460)
12.3 73.7 GO:0050733 RS domain binding(GO:0050733)
12.3 233.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
12.3 49.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
12.3 24.6 GO:0005128 erythropoietin receptor binding(GO:0005128)
12.3 73.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
12.2 134.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
12.2 219.6 GO:0001056 RNA polymerase III activity(GO:0001056)
12.2 109.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
12.1 109.3 GO:0008432 JUN kinase binding(GO:0008432)
12.1 121.1 GO:0050811 GABA receptor binding(GO:0050811)
12.1 156.8 GO:0015928 fucosidase activity(GO:0015928)
12.1 24.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
12.0 204.4 GO:0043531 ADP binding(GO:0043531)
12.0 35.9 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
11.9 238.7 GO:0001221 transcription cofactor binding(GO:0001221)
11.9 71.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
11.9 59.4 GO:0070728 leucine binding(GO:0070728)
11.8 47.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
11.8 106.0 GO:0039706 co-receptor binding(GO:0039706)
11.7 493.0 GO:0019209 kinase activator activity(GO:0019209)
11.7 152.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
11.7 23.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
11.6 69.6 GO:0030274 LIM domain binding(GO:0030274)
11.6 34.7 GO:0000339 RNA cap binding(GO:0000339)
11.6 11.6 GO:0032552 deoxyribonucleotide binding(GO:0032552)
11.5 92.3 GO:0043176 amine binding(GO:0043176)
11.5 11.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
11.5 298.5 GO:0070063 RNA polymerase binding(GO:0070063)
11.4 57.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
11.4 159.0 GO:0017049 GTP-Rho binding(GO:0017049)
11.3 34.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
11.3 33.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
11.3 33.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
11.3 112.7 GO:0045295 gamma-catenin binding(GO:0045295)
11.2 33.7 GO:1990226 histone methyltransferase binding(GO:1990226)
11.2 33.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
11.2 550.1 GO:0017048 Rho GTPase binding(GO:0017048)
11.2 179.6 GO:0001848 complement binding(GO:0001848)
11.2 56.1 GO:0017040 ceramidase activity(GO:0017040)
11.2 100.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
11.2 22.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
11.2 368.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
11.2 44.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
11.1 244.6 GO:0004177 aminopeptidase activity(GO:0004177)
11.1 111.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
11.1 33.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
11.1 199.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
11.1 11.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
11.0 66.0 GO:0043522 leucine zipper domain binding(GO:0043522)
11.0 109.8 GO:0004016 adenylate cyclase activity(GO:0004016)
11.0 54.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
10.9 32.8 GO:0097322 7SK snRNA binding(GO:0097322)
10.9 568.5 GO:0051087 chaperone binding(GO:0051087)
10.9 43.7 GO:0043237 laminin-1 binding(GO:0043237)
10.9 32.8 GO:0030492 hemoglobin binding(GO:0030492)
10.9 98.2 GO:0030983 mismatched DNA binding(GO:0030983)
10.9 43.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
10.9 21.8 GO:0070538 oleic acid binding(GO:0070538)
10.9 32.6 GO:0030911 TPR domain binding(GO:0030911)
10.8 97.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
10.8 53.8 GO:0015288 porin activity(GO:0015288)
10.7 75.2 GO:0034046 poly(G) binding(GO:0034046)
10.7 128.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
10.7 32.1 GO:0003696 satellite DNA binding(GO:0003696)
10.7 64.1 GO:0000150 recombinase activity(GO:0000150)
10.7 21.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
10.7 224.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
10.7 128.0 GO:0016830 carbon-carbon lyase activity(GO:0016830)
10.7 32.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
10.7 10.7 GO:0008200 ion channel inhibitor activity(GO:0008200)
10.7 42.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
10.6 159.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
10.6 42.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
10.6 159.0 GO:0008327 methyl-CpG binding(GO:0008327)
10.6 127.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
10.5 10.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
10.5 263.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
10.5 31.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
10.5 168.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
10.5 73.5 GO:0001671 ATPase activator activity(GO:0001671)
10.5 21.0 GO:0050816 phosphothreonine binding(GO:0050816)
10.5 73.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
10.5 303.4 GO:0016748 succinyltransferase activity(GO:0016748) N-succinyltransferase activity(GO:0016749)
10.4 41.8 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
10.4 73.1 GO:0008430 selenium binding(GO:0008430)
10.4 31.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
10.4 93.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
10.4 20.7 GO:0043842 Kdo transferase activity(GO:0043842)
10.3 51.5 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
10.3 10.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
10.3 925.0 GO:0017137 Rab GTPase binding(GO:0017137)
10.2 41.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
10.2 40.9 GO:0016778 diphosphotransferase activity(GO:0016778)
10.2 20.5 GO:0035877 death effector domain binding(GO:0035877)
10.2 30.6 GO:0004046 aminoacylase activity(GO:0004046)
10.2 81.3 GO:0005123 death receptor binding(GO:0005123)
10.1 172.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
10.1 30.4 GO:0032027 myosin light chain binding(GO:0032027)
10.1 90.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
10.1 655.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
10.0 70.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
10.0 40.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
10.0 837.2 GO:0008171 O-methyltransferase activity(GO:0008171)
10.0 29.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
10.0 119.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
9.9 129.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
9.9 49.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
9.9 9.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
9.9 79.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
9.9 9.9 GO:0016418 S-acetyltransferase activity(GO:0016418)
9.9 9.9 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
9.9 9.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
9.9 39.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
9.9 49.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
9.8 29.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
9.8 19.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
9.8 392.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
9.8 49.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
9.8 78.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
9.8 29.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
9.7 29.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
9.7 272.1 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
9.7 77.4 GO:0003993 acid phosphatase activity(GO:0003993)
9.7 125.7 GO:0008143 poly(A) binding(GO:0008143)
9.6 57.8 GO:0005113 patched binding(GO:0005113)
9.6 86.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
9.6 9.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
9.6 325.4 GO:0070491 repressing transcription factor binding(GO:0070491)
9.5 105.0 GO:0017154 semaphorin receptor activity(GO:0017154)
9.5 28.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
9.5 28.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
9.5 38.0 GO:0036310 annealing helicase activity(GO:0036310)
9.5 66.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
9.5 56.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
9.5 56.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
9.5 37.9 GO:0004966 galanin receptor activity(GO:0004966)
9.4 113.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
9.4 9.4 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
9.4 56.5 GO:0045545 syndecan binding(GO:0045545)
9.4 206.4 GO:0004118 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
9.4 9.4 GO:0000403 Y-form DNA binding(GO:0000403)
9.3 112.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
9.3 74.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
9.3 46.6 GO:0071949 FAD binding(GO:0071949)
9.3 612.4 GO:0008565 protein transporter activity(GO:0008565)
9.3 74.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
9.2 83.0 GO:0034871 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
9.1 9.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
9.1 18.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
9.1 9.1 GO:0070698 type I activin receptor binding(GO:0070698)
9.1 54.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
9.1 54.5 GO:0008097 5S rRNA binding(GO:0008097)
9.1 36.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
9.0 18.0 GO:0050897 cobalt ion binding(GO:0050897)
9.0 27.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
9.0 449.9 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
9.0 36.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
9.0 35.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
9.0 26.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
9.0 44.8 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
9.0 9.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
8.9 80.5 GO:0055102 lipase inhibitor activity(GO:0055102)
8.9 17.8 GO:0017098 sulfonylurea receptor binding(GO:0017098)
8.9 115.8 GO:0015026 coreceptor activity(GO:0015026)
8.9 79.9 GO:0004697 protein kinase C activity(GO:0004697)
8.8 17.7 GO:0004977 melanocortin receptor activity(GO:0004977)
8.8 35.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
8.8 61.6 GO:0070182 DNA polymerase binding(GO:0070182)
8.8 35.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
8.7 43.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
8.7 8.7 GO:0034618 arginine binding(GO:0034618)
8.7 8.7 GO:0008142 oxysterol binding(GO:0008142)
8.7 355.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
8.7 104.1 GO:0004527 exonuclease activity(GO:0004527)
8.7 34.7 GO:0034185 apolipoprotein binding(GO:0034185)
8.7 17.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
8.7 17.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
8.6 441.0 GO:0003697 single-stranded DNA binding(GO:0003697)
8.6 25.9 GO:0055103 ligase regulator activity(GO:0055103)
8.6 395.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
8.6 8.6 GO:0003916 DNA topoisomerase activity(GO:0003916)
8.6 8.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
8.6 8.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
8.6 25.7 GO:0070569 uridylyltransferase activity(GO:0070569)
8.5 102.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
8.5 392.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
8.5 25.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
8.4 76.0 GO:0002039 p53 binding(GO:0002039)
8.4 16.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
8.4 75.8 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
8.4 8.4 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
8.4 108.6 GO:0000049 tRNA binding(GO:0000049)
8.3 16.6 GO:1990188 euchromatin binding(GO:1990188)
8.3 199.7 GO:0003684 damaged DNA binding(GO:0003684)
8.3 74.8 GO:0019841 retinol binding(GO:0019841)
8.3 58.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
8.3 66.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
8.2 16.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
8.2 33.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
8.2 90.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
8.2 24.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
8.2 8.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
8.2 8.2 GO:0003933 GTP cyclohydrolase activity(GO:0003933) cyclohydrolase activity(GO:0019238)
8.1 105.9 GO:0008252 nucleotidase activity(GO:0008252)
8.1 24.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
8.1 16.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
8.1 81.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
8.1 40.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
8.1 8.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
8.1 32.2 GO:0042015 interleukin-20 binding(GO:0042015)
8.1 56.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
8.0 40.2 GO:1990405 protein antigen binding(GO:1990405)
8.0 16.0 GO:0015377 cation:chloride symporter activity(GO:0015377)
8.0 96.1 GO:0008198 ferrous iron binding(GO:0008198)
8.0 56.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
8.0 24.0 GO:1990446 U1 snRNP binding(GO:1990446)
8.0 40.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
8.0 39.9 GO:0004457 lactate dehydrogenase activity(GO:0004457)
8.0 8.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
8.0 477.0 GO:0004540 ribonuclease activity(GO:0004540)
7.9 127.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
7.9 7.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
7.9 15.8 GO:0070061 fructose binding(GO:0070061)
7.9 39.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
7.9 31.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
7.9 196.6 GO:0052770 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
7.8 7.8 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
7.8 23.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
7.8 23.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
7.8 62.4 GO:0031996 thioesterase binding(GO:0031996)
7.7 30.9 GO:0001055 RNA polymerase II activity(GO:0001055)
7.7 292.2 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
7.7 23.0 GO:0071209 U7 snRNA binding(GO:0071209)
7.7 53.6 GO:0048406 nerve growth factor binding(GO:0048406)
7.6 137.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
7.6 22.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
7.6 76.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
7.6 15.2 GO:0019789 SUMO transferase activity(GO:0019789)
7.6 38.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
7.6 227.9 GO:0031593 polyubiquitin binding(GO:0031593)
7.6 30.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
7.5 128.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
7.5 37.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
7.5 180.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
7.5 22.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
7.5 44.9 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
7.4 81.6 GO:0030145 manganese ion binding(GO:0030145)
7.4 14.8 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
7.4 29.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
7.4 22.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
7.4 22.1 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
7.4 51.6 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
7.4 29.4 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
7.3 51.4 GO:0050321 tau-protein kinase activity(GO:0050321)
7.3 29.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
7.3 219.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
7.3 65.8 GO:0008536 Ran GTPase binding(GO:0008536)
7.3 349.7 GO:0016836 hydro-lyase activity(GO:0016836)
7.3 51.0 GO:0070325 lipoprotein particle receptor binding(GO:0070325)
7.3 21.8 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
7.3 123.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
7.2 14.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
7.2 14.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
7.1 14.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
7.1 14.3 GO:0042577 lipid phosphatase activity(GO:0042577)
7.1 299.7 GO:0008168 methyltransferase activity(GO:0008168)
7.1 917.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
7.1 14.2 GO:0046848 hydroxyapatite binding(GO:0046848)
7.1 21.3 GO:0019213 deacetylase activity(GO:0019213)
7.1 7.1 GO:0051380 norepinephrine binding(GO:0051380)
7.1 28.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
7.1 642.7 GO:0019902 phosphatase binding(GO:0019902)
7.0 7.0 GO:0036033 mediator complex binding(GO:0036033)
7.0 98.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
7.0 132.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
7.0 76.6 GO:0030552 cAMP binding(GO:0030552)
7.0 34.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
6.9 13.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
6.9 13.9 GO:0051373 FATZ binding(GO:0051373)
6.9 97.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
6.9 27.6 GO:0003905 alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
6.9 96.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
6.8 27.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
6.8 34.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
6.8 81.9 GO:0033613 activating transcription factor binding(GO:0033613)
6.8 13.6 GO:1990715 mRNA CDS binding(GO:1990715)
6.8 183.7 GO:0005484 SNAP receptor activity(GO:0005484)
6.8 61.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
6.8 115.3 GO:0030515 snoRNA binding(GO:0030515)
6.8 6.8 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
6.8 6.8 GO:0017081 chloride channel regulator activity(GO:0017081)
6.7 33.7 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
6.7 13.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
6.7 93.7 GO:0031489 myosin V binding(GO:0031489)
6.7 46.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
6.7 133.4 GO:0043130 ubiquitin binding(GO:0043130)
6.7 6.7 GO:0052744 phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
6.6 19.9 GO:0005000 vasopressin receptor activity(GO:0005000)
6.6 6.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
6.6 26.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
6.6 13.2 GO:0008147 structural constituent of bone(GO:0008147)
6.6 13.2 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
6.6 164.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
6.6 702.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
6.5 13.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
6.5 26.0 GO:0045294 alpha-catenin binding(GO:0045294)
6.5 19.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
6.5 32.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
6.5 32.4 GO:0001054 RNA polymerase I activity(GO:0001054)
6.4 109.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
6.4 442.7 GO:0017124 SH3 domain binding(GO:0017124)
6.4 108.9 GO:0051059 NF-kappaB binding(GO:0051059)
6.4 25.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
6.4 38.2 GO:0051011 microtubule minus-end binding(GO:0051011)
6.3 31.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
6.3 12.6 GO:0030621 U4 snRNA binding(GO:0030621)
6.3 6.3 GO:0034061 DNA polymerase activity(GO:0034061)
6.3 37.7 GO:0004630 phospholipase D activity(GO:0004630)
6.3 18.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
6.3 6.3 GO:0016866 intramolecular transferase activity(GO:0016866)
6.2 18.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
6.2 24.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
6.2 74.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
6.1 18.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
6.1 6.1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
6.1 18.3 GO:0004385 guanylate kinase activity(GO:0004385)
6.1 18.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
6.1 6.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
6.1 79.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
6.1 54.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
6.1 24.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
6.1 18.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
6.0 6.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
6.0 18.1 GO:0004995 tachykinin receptor activity(GO:0004995)
6.0 84.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
6.0 48.1 GO:0051018 protein kinase A binding(GO:0051018)
6.0 12.0 GO:0000182 rDNA binding(GO:0000182)
6.0 53.9 GO:0032182 ubiquitin-like protein binding(GO:0032182)
6.0 53.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
5.9 77.3 GO:0031369 translation initiation factor binding(GO:0031369)
5.9 65.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
5.9 17.8 GO:0048030 disaccharide binding(GO:0048030)
5.9 11.8 GO:0004672 protein kinase activity(GO:0004672)
5.9 65.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
5.9 5.9 GO:0015197 peptide transporter activity(GO:0015197)
5.8 5.8 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
5.8 11.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
5.8 227.0 GO:0008234 cysteine-type peptidase activity(GO:0008234)
5.8 34.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
5.8 46.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
5.8 11.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
5.7 23.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
5.7 51.6 GO:0004383 guanylate cyclase activity(GO:0004383)
5.7 28.7 GO:0050700 CARD domain binding(GO:0050700)
5.7 96.9 GO:0008201 heparin binding(GO:0008201)
5.7 22.8 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
5.7 11.4 GO:0016853 isomerase activity(GO:0016853)
5.7 22.8 GO:0004370 glycerol kinase activity(GO:0004370)
5.7 11.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
5.7 17.0 GO:0019767 IgE receptor activity(GO:0019767)
5.7 5.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
5.7 33.9 GO:0031386 protein tag(GO:0031386)
5.6 242.1 GO:0008417 fucosyltransferase activity(GO:0008417)
5.6 44.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
5.6 11.2 GO:0032036 myosin heavy chain binding(GO:0032036)
5.6 67.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
5.6 27.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
5.6 83.8 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(GO:0016818)
5.6 133.5 GO:0015485 cholesterol binding(GO:0015485)
5.5 11.1 GO:0038132 neuregulin binding(GO:0038132)
5.5 27.7 GO:0008420 CTD phosphatase activity(GO:0008420)
5.5 16.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
5.5 22.0 GO:0004000 adenosine deaminase activity(GO:0004000)
5.5 16.5 GO:0004645 phosphorylase activity(GO:0004645)
5.5 5.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
5.5 16.5 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
5.5 11.0 GO:0019776 Atg8 ligase activity(GO:0019776)
5.5 11.0 GO:0070052 collagen V binding(GO:0070052)
5.5 54.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
5.5 120.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
5.4 5.4 GO:0035325 Toll-like receptor binding(GO:0035325) Toll-like receptor 4 binding(GO:0035662)
5.4 146.4 GO:0003725 double-stranded RNA binding(GO:0003725)
5.4 48.8 GO:0051879 Hsp90 protein binding(GO:0051879)
5.4 32.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
5.4 436.1 GO:0003714 transcription corepressor activity(GO:0003714)
5.4 16.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
5.4 10.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
5.4 32.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
5.4 26.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
5.4 10.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
5.3 10.7 GO:0043515 kinetochore binding(GO:0043515)
5.3 181.5 GO:0004518 nuclease activity(GO:0004518)
5.3 58.7 GO:0017091 AU-rich element binding(GO:0017091)
5.3 26.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
5.3 26.5 GO:0017025 TBP-class protein binding(GO:0017025)
5.3 37.0 GO:0017166 vinculin binding(GO:0017166)
5.3 5.3 GO:0030545 receptor regulator activity(GO:0030545)
5.3 152.6 GO:0005507 copper ion binding(GO:0005507)
5.3 42.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
5.2 62.8 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
5.2 31.4 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
5.2 26.0 GO:0005499 vitamin D binding(GO:0005499)
5.2 10.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
5.2 10.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
5.1 51.5 GO:0043015 gamma-tubulin binding(GO:0043015)
5.1 15.4 GO:0031014 troponin T binding(GO:0031014)
5.1 5.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
5.1 35.9 GO:0032451 demethylase activity(GO:0032451)
5.1 187.6 GO:0042826 histone deacetylase binding(GO:0042826)
5.1 5.1 GO:0045182 translation regulator activity(GO:0045182)
5.0 1046.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
5.0 854.6 GO:0003735 structural constituent of ribosome(GO:0003735)
5.0 50.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
5.0 45.1 GO:0004622 lysophospholipase activity(GO:0004622)
5.0 250.4 GO:0004896 cytokine receptor activity(GO:0004896)
5.0 154.9 GO:0003743 translation initiation factor activity(GO:0003743)
5.0 19.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
5.0 224.0 GO:0000149 SNARE binding(GO:0000149)
5.0 64.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
5.0 84.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
5.0 9.9 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
5.0 163.4 GO:0042562 hormone binding(GO:0042562)
4.9 44.5 GO:0022821 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
4.9 19.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
4.9 98.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
4.9 4.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
4.9 4.9 GO:0008061 chitin binding(GO:0008061)
4.8 150.2 GO:0015923 mannosidase activity(GO:0015923)
4.8 130.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
4.8 24.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
4.8 19.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
4.8 9.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
4.8 243.4 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
4.8 142.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
4.8 9.5 GO:0016841 ammonia-lyase activity(GO:0016841)
4.7 61.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
4.7 56.8 GO:0090484 drug transporter activity(GO:0090484)
4.7 89.6 GO:0043621 protein self-association(GO:0043621)
4.7 47.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
4.7 51.6 GO:0004175 endopeptidase activity(GO:0004175)
4.7 46.6 GO:0005523 tropomyosin binding(GO:0005523)
4.7 4.7 GO:0019863 IgE binding(GO:0019863)
4.6 13.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
4.6 13.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
4.6 51.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
4.6 92.7 GO:0051082 unfolded protein binding(GO:0051082)
4.6 18.5 GO:0070566 adenylyltransferase activity(GO:0070566)
4.6 4.6 GO:0008905 mannose-phosphate guanylyltransferase activity(GO:0008905)
4.6 13.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
4.6 23.0 GO:0004180 carboxypeptidase activity(GO:0004180)
4.6 18.4 GO:0019966 interleukin-1 binding(GO:0019966)
4.6 4.6 GO:0051213 dioxygenase activity(GO:0051213)
4.6 22.9 GO:0000287 magnesium ion binding(GO:0000287)
4.6 2434.2 GO:0044822 poly(A) RNA binding(GO:0044822)
4.6 18.3 GO:0070513 death domain binding(GO:0070513)
4.6 500.6 GO:0005096 GTPase activator activity(GO:0005096)
4.5 117.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
4.5 121.6 GO:0047485 protein N-terminus binding(GO:0047485)
4.5 18.0 GO:0048038 quinone binding(GO:0048038)
4.5 4.5 GO:0036222 dITP diphosphatase activity(GO:0035870) XTP diphosphatase activity(GO:0036222)
4.4 17.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
4.4 8.9 GO:0005534 galactose binding(GO:0005534)
4.4 35.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
4.4 22.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
4.4 13.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
4.4 4.4 GO:0034452 dynactin binding(GO:0034452)
4.4 8.8 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
4.4 17.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
4.4 39.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
4.4 13.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
4.3 30.3 GO:0017160 Ral GTPase binding(GO:0017160)
4.3 43.3 GO:0005158 insulin receptor binding(GO:0005158)
4.3 4.3 GO:0019862 IgA binding(GO:0019862)
4.3 8.5 GO:0015250 water channel activity(GO:0015250)
4.3 4.3 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
4.2 42.3 GO:0070888 E-box binding(GO:0070888)
4.2 126.7 GO:0005132 type I interferon receptor binding(GO:0005132)
4.2 46.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
4.2 25.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
4.2 4.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
4.2 12.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
4.2 20.9 GO:0031849 olfactory receptor binding(GO:0031849)
4.2 16.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
4.2 183.6 GO:0016791 phosphatase activity(GO:0016791)
4.2 4.2 GO:0016783 sulfurtransferase activity(GO:0016783)
4.2 4.2 GO:0016015 morphogen activity(GO:0016015)
4.1 29.0 GO:0031491 nucleosome binding(GO:0031491)
4.1 24.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
4.1 102.9 GO:0016887 ATPase activity(GO:0016887)
4.1 834.3 GO:0046982 protein heterodimerization activity(GO:0046982)
4.1 8.2 GO:0009975 cyclase activity(GO:0009975)
4.1 20.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
4.1 164.1 GO:0001047 core promoter binding(GO:0001047)
4.1 352.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
4.1 16.2 GO:0016421 CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
4.0 60.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
4.0 8.0 GO:0051185 coenzyme transporter activity(GO:0051185)
4.0 16.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
4.0 16.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
4.0 307.3 GO:0003774 motor activity(GO:0003774)
4.0 79.6 GO:0042605 peptide antigen binding(GO:0042605)
4.0 39.6 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
4.0 110.8 GO:0050840 extracellular matrix binding(GO:0050840)
4.0 19.8 GO:0005319 lipid transporter activity(GO:0005319)
3.9 11.8 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
3.9 11.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
3.9 11.7 GO:0042043 neurexin family protein binding(GO:0042043)
3.9 38.8 GO:0042805 actinin binding(GO:0042805)
3.8 72.4 GO:0005212 structural constituent of eye lens(GO:0005212)
3.8 462.6 GO:0003723 RNA binding(GO:0003723)
3.8 41.6 GO:0004364 glutathione transferase activity(GO:0004364)
3.8 3.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
3.8 7.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
3.7 223.0 GO:0003712 transcription cofactor activity(GO:0003712)
3.7 25.9 GO:0003796 lysozyme activity(GO:0003796)
3.7 3.7 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
3.7 7.4 GO:0043199 sulfate binding(GO:0043199)
3.7 22.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
3.7 43.8 GO:0004386 helicase activity(GO:0004386)
3.6 3.6 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
3.6 36.3 GO:0043566 structure-specific DNA binding(GO:0043566)
3.6 54.1 GO:0004623 phospholipase A2 activity(GO:0004623)
3.6 139.5 GO:0042393 histone binding(GO:0042393)
3.5 24.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
3.5 35.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
3.5 292.2 GO:0004857 enzyme inhibitor activity(GO:0004857)
3.5 1126.6 GO:0042802 identical protein binding(GO:0042802)
3.5 41.4 GO:0042578 phosphoric ester hydrolase activity(GO:0042578)
3.4 41.3 GO:0005539 glycosaminoglycan binding(GO:0005539)
3.4 153.5 GO:0005262 calcium channel activity(GO:0005262)
3.4 346.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
3.4 6.8 GO:0015643 toxic substance binding(GO:0015643)
3.4 6.8 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
3.3 53.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
3.3 19.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
3.3 23.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
3.3 3.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
3.2 54.9 GO:0030674 protein binding, bridging(GO:0030674)
3.2 19.2 GO:0019865 immunoglobulin binding(GO:0019865)
3.2 389.5 GO:0019900 kinase binding(GO:0019900)
3.2 3.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
3.2 28.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
3.2 6.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
3.1 37.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
3.1 6.2 GO:0001595 angiotensin receptor activity(GO:0001595)
3.1 43.4 GO:0000988 transcription factor activity, protein binding(GO:0000988)
3.1 21.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
3.0 3.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
3.0 130.3 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
3.0 287.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
2.9 26.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
2.9 82.3 GO:0005496 steroid binding(GO:0005496)
2.9 137.2 GO:0046983 protein dimerization activity(GO:0046983)
2.9 5.8 GO:0002046 opsin binding(GO:0002046)
2.9 5.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
2.9 5.7 GO:0003987 acetate-CoA ligase activity(GO:0003987)
2.9 14.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.9 80.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.8 22.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
2.8 5.7 GO:0042301 phosphate ion binding(GO:0042301)
2.8 19.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
2.8 16.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
2.8 22.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
2.7 71.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
2.7 10.9 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
2.7 455.9 GO:0005525 GTP binding(GO:0005525)
2.6 31.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
2.6 2.6 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
2.6 7.8 GO:1901677 phosphate transmembrane transporter activity(GO:1901677)
2.6 5.2 GO:0034235 GPI anchor binding(GO:0034235)
2.6 13.0 GO:0042288 MHC class I protein binding(GO:0042288)
2.6 224.9 GO:0019904 protein domain specific binding(GO:0019904)
2.6 10.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
2.5 7.6 GO:0061135 endopeptidase regulator activity(GO:0061135)
2.5 2.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.5 196.3 GO:0003682 chromatin binding(GO:0003682)
2.5 42.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.5 7.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.4 2.4 GO:0042809 vitamin D receptor binding(GO:0042809)
2.4 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
2.4 12.1 GO:0061134 peptidase regulator activity(GO:0061134)
2.4 7.2 GO:0035326 enhancer binding(GO:0035326)
2.4 333.8 GO:0046872 metal ion binding(GO:0046872)
2.4 7.1 GO:0016209 antioxidant activity(GO:0016209)
2.4 283.6 GO:0005509 calcium ion binding(GO:0005509)
2.4 4.7 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
2.3 18.7 GO:0005272 sodium channel activity(GO:0005272)
2.3 9.3 GO:0004985 opioid receptor activity(GO:0004985)
2.3 20.9 GO:0051117 ATPase binding(GO:0051117)
2.3 4.6 GO:0016018 cyclosporin A binding(GO:0016018)
2.3 18.3 GO:0004312 fatty acid synthase activity(GO:0004312)
2.3 1187.9 GO:0003676 nucleic acid binding(GO:0003676)
2.2 4.5 GO:0042056 chemoattractant activity(GO:0042056)
2.2 2.2 GO:0019534 toxin transporter activity(GO:0019534)
2.2 24.1 GO:0005537 mannose binding(GO:0005537)
2.2 21.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
2.2 169.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
2.2 4.3 GO:0016415 octanoyltransferase activity(GO:0016415)
2.1 38.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.1 4.2 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
2.1 2.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
2.0 2.0 GO:0004461 lactose synthase activity(GO:0004461)
2.0 6.1 GO:0019842 vitamin binding(GO:0019842)
2.0 59.6 GO:0020037 heme binding(GO:0020037)
2.0 277.1 GO:0017171 serine hydrolase activity(GO:0017171)
2.0 413.0 GO:0008270 zinc ion binding(GO:0008270)
1.9 1.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.9 16.9 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
1.9 7.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
1.8 133.5 GO:0005524 ATP binding(GO:0005524)
1.8 3.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.8 102.9 GO:0030246 carbohydrate binding(GO:0030246)
1.8 28.8 GO:0008134 transcription factor binding(GO:0008134)
1.8 7.2 GO:0051183 vitamin transporter activity(GO:0051183)
1.8 33.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
1.7 48.9 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
1.7 1.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
1.7 5.2 GO:0003823 antigen binding(GO:0003823)
1.7 11.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.7 1.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.7 151.7 GO:0005550 pheromone binding(GO:0005550)
1.7 2734.2 GO:0005515 protein binding(GO:0005515)
1.6 1.6 GO:0008410 CoA-transferase activity(GO:0008410)
1.6 6.5 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
1.6 25.6 GO:0016790 thiolester hydrolase activity(GO:0016790)
1.6 1.6 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.5 15.3 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
1.5 1.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.4 31.4 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
1.4 2.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.4 1.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
1.4 10.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
1.3 103.3 GO:0008289 lipid binding(GO:0008289)
1.3 5.3 GO:0004974 leukotriene receptor activity(GO:0004974)
1.3 3.9 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
1.3 28.6 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)
1.3 1.3 GO:0038181 bile acid receptor activity(GO:0038181)
1.3 1.3 GO:0004954 prostanoid receptor activity(GO:0004954)
1.2 2.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.2 1.2 GO:0015927 trehalase activity(GO:0015927)
1.2 1.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
1.2 1297.9 GO:0004984 olfactory receptor activity(GO:0004984)
1.0 3.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
1.0 24.3 GO:0000166 nucleotide binding(GO:0000166) nucleoside phosphate binding(GO:1901265)
0.9 13.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.9 0.9 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.8 2.4 GO:0008509 anion transmembrane transporter activity(GO:0008509)
0.8 9.3 GO:0016247 channel regulator activity(GO:0016247)
0.6 116.6 GO:0004871 signal transducer activity(GO:0004871)
0.5 34.7 GO:0005215 transporter activity(GO:0005215)
0.5 2.9 GO:0008932 lytic endotransglycosylase activity(GO:0008932)
0.5 0.9 GO:0008144 drug binding(GO:0008144)
0.4 9.7 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)
0.4 37.8 GO:0005198 structural molecule activity(GO:0005198)
0.4 1.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.8 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
34.9 488.9 PID IL5 PATHWAY IL5-mediated signaling events
27.5 826.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
27.0 296.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
19.4 77.4 ST STAT3 PATHWAY STAT3 Pathway
18.8 470.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
18.7 615.7 PID ARF6 PATHWAY Arf6 signaling events
18.5 443.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
17.7 194.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
16.6 199.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
16.5 990.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
16.4 82.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
16.2 129.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
16.1 80.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
16.0 415.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
15.5 216.3 PID IGF1 PATHWAY IGF1 pathway
14.9 133.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
14.8 191.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
14.7 132.4 PID EPO PATHWAY EPO signaling pathway
14.6 248.9 PID ARF 3PATHWAY Arf1 pathway
14.6 43.8 PID FAS PATHWAY FAS (CD95) signaling pathway
14.5 320.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
14.4 158.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
13.9 320.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
13.9 332.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
13.7 425.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
13.7 370.1 PID RHOA PATHWAY RhoA signaling pathway
13.4 13.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
13.4 401.6 PID ATR PATHWAY ATR signaling pathway
12.8 256.3 PID AURORA A PATHWAY Aurora A signaling
12.8 589.5 PID TELOMERASE PATHWAY Regulation of Telomerase
12.7 698.8 PID CMYB PATHWAY C-MYB transcription factor network
12.6 339.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
12.4 62.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
12.3 24.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
12.1 289.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
12.0 132.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
11.9 417.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
11.9 570.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
11.9 47.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
11.7 23.5 ST GAQ PATHWAY G alpha q Pathway
11.6 46.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
11.1 78.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
10.7 117.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
10.7 10.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
10.5 146.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
10.3 351.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
10.2 50.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
10.2 111.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
10.1 80.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
10.0 90.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
10.0 79.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
9.9 248.7 PID PLK1 PATHWAY PLK1 signaling events
9.9 89.0 PID BARD1 PATHWAY BARD1 signaling events
9.8 107.9 PID IL6 7 PATHWAY IL6-mediated signaling events
9.6 133.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
9.5 294.5 PID AR PATHWAY Coregulation of Androgen receptor activity
9.5 161.2 PID TNF PATHWAY TNF receptor signaling pathway
9.4 150.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
9.3 102.1 PID IFNG PATHWAY IFN-gamma pathway
9.2 73.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
9.2 45.9 PID IL3 PATHWAY IL3-mediated signaling events
9.2 605.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
9.0 171.8 PID FOXO PATHWAY FoxO family signaling
8.9 26.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
8.8 396.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
8.8 26.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
8.6 120.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
8.6 284.1 PID E2F PATHWAY E2F transcription factor network
8.5 93.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
8.5 136.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
8.5 110.4 PID ERBB4 PATHWAY ErbB4 signaling events
8.4 185.8 PID LKB1 PATHWAY LKB1 signaling events
8.4 100.7 PID LPA4 PATHWAY LPA4-mediated signaling events
8.2 57.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
8.1 40.7 PID IL2 1PATHWAY IL2-mediated signaling events
8.0 56.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
8.0 152.6 PID CONE PATHWAY Visual signal transduction: Cones
8.0 120.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
8.0 16.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
8.0 183.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
7.9 71.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
7.8 117.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
7.8 38.8 PID ATM PATHWAY ATM pathway
7.7 84.2 PID CDC42 PATHWAY CDC42 signaling events
7.7 107.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
7.3 146.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
7.2 108.0 PID P53 REGULATION PATHWAY p53 pathway
6.9 125.0 PID IL12 2PATHWAY IL12-mediated signaling events
6.8 13.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
6.7 40.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
6.7 141.0 PID AURORA B PATHWAY Aurora B signaling
6.6 13.2 SIG CHEMOTAXIS Genes related to chemotaxis
6.5 98.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
6.5 32.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
6.5 135.8 PID P73PATHWAY p73 transcription factor network
6.5 64.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
6.4 51.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
6.3 107.4 PID ILK PATHWAY Integrin-linked kinase signaling
6.2 18.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
6.2 210.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
6.1 128.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
5.9 64.8 PID IL1 PATHWAY IL1-mediated signaling events
5.8 58.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
5.8 17.4 PID GLYPICAN 1PATHWAY Glypican 1 network
5.6 50.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
5.6 156.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
5.6 5.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
5.5 60.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
5.4 37.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
5.3 89.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
5.2 103.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
5.1 35.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
5.0 25.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
4.8 62.7 PID RAS PATHWAY Regulation of Ras family activation
4.8 85.9 PID MTOR 4PATHWAY mTOR signaling pathway
4.7 23.6 ST G ALPHA S PATHWAY G alpha s Pathway
4.7 28.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
4.5 4.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
4.3 21.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
4.3 64.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
4.3 55.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
4.2 193.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
4.2 54.1 PID AP1 PATHWAY AP-1 transcription factor network
4.1 28.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
4.1 8.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
3.9 34.9 PID IL23 PATHWAY IL23-mediated signaling events
3.8 34.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
3.8 26.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
3.7 44.6 PID FANCONI PATHWAY Fanconi anemia pathway
3.6 10.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
3.6 678.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
3.6 42.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
3.4 10.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
3.4 27.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
3.4 41.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
3.4 13.6 PID ALK2 PATHWAY ALK2 signaling events
3.4 30.4 PID RAC1 PATHWAY RAC1 signaling pathway
3.3 20.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
3.3 26.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
3.3 6.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
3.3 32.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
3.1 40.8 PID IL4 2PATHWAY IL4-mediated signaling events
3.1 18.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
2.9 5.8 PID TRAIL PATHWAY TRAIL signaling pathway
2.7 361.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.6 26.2 PID TGFBR PATHWAY TGF-beta receptor signaling
2.6 41.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
2.5 5.1 PID CD40 PATHWAY CD40/CD40L signaling
2.5 24.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
2.3 23.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
2.3 58.0 PID BMP PATHWAY BMP receptor signaling
2.3 18.6 PID BCR 5PATHWAY BCR signaling pathway
2.3 29.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
2.3 11.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.3 6.8 PID IL27 PATHWAY IL27-mediated signaling events
2.1 19.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.9 11.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.9 11.5 PID ATF2 PATHWAY ATF-2 transcription factor network
1.8 3.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.8 1.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.7 3.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.7 6.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
1.6 9.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.6 11.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
1.5 11.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.3 6.3 PID PI3KCI PATHWAY Class I PI3K signaling events
1.2 9.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.2 13.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
1.2 207.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
1.1 2.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
1.1 13.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
1.0 1.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.9 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.7 112.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
66.3 927.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
53.0 635.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
48.9 489.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
45.0 449.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
43.5 391.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
34.9 34.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
34.2 376.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
33.5 100.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
33.1 562.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
31.9 255.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
30.8 307.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
28.9 434.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
28.8 28.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
28.5 342.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
28.2 225.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
26.7 186.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
26.3 263.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
24.3 97.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
22.3 513.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
22.3 178.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
22.1 154.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
21.6 86.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
19.8 535.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
19.8 158.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
19.5 175.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
18.8 169.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
18.7 393.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
18.5 332.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
18.0 72.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
17.7 673.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
17.5 244.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
17.2 344.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
17.2 257.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
17.1 188.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
17.1 291.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
16.9 67.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
16.8 100.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
16.2 97.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
15.9 461.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
15.9 111.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
15.7 392.6 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
15.5 200.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
15.4 416.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
15.3 45.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
15.3 45.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
15.2 213.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
15.2 213.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
15.1 166.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
15.0 676.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
15.0 403.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
14.9 148.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
14.7 219.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
14.4 114.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
14.2 184.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
14.2 85.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
14.1 127.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
14.1 42.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
14.0 308.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
14.0 153.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
13.6 13.6 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
13.5 406.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
13.5 27.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
13.5 94.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
13.5 188.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
13.4 120.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
13.4 173.6 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
13.3 106.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
13.2 290.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
13.2 52.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
13.1 196.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
13.0 325.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
12.8 653.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
12.8 369.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
12.6 37.9 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
12.5 374.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
12.3 503.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
12.2 12.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
12.2 972.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
12.1 278.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
12.1 60.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
12.1 144.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
11.9 11.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
11.7 35.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
11.7 58.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
11.6 69.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
11.5 23.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
11.5 92.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
11.4 262.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
11.3 22.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
11.3 11.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
11.3 11.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
11.2 280.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
11.2 55.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
11.1 211.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
11.1 122.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
11.0 308.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
10.9 328.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
10.9 119.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
10.8 53.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
10.8 183.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
10.7 21.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
10.7 107.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
10.6 170.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
10.6 190.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
10.5 10.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
10.5 231.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
10.5 231.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
10.5 84.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
10.5 104.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
10.2 81.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
10.1 60.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
10.1 10.1 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
10.1 596.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
10.1 181.0 REACTOME G1 PHASE Genes involved in G1 Phase
10.0 338.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
10.0 109.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
10.0 567.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
9.9 138.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
9.8 108.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
9.7 9.7 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
9.6 124.7 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
9.4 9.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
9.3 204.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
9.1 73.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
9.1 72.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
9.1 99.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
9.0 81.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
9.0 45.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
9.0 483.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
8.8 52.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
8.8 123.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
8.7 96.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
8.7 445.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
8.5 136.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
8.5 271.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
8.5 50.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
8.4 226.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
8.2 155.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
8.1 48.8 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
8.1 161.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
8.1 88.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
8.1 64.4 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
8.0 263.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
7.9 103.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
7.9 23.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
7.9 70.7 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
7.8 46.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
7.7 61.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
7.7 38.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
7.7 199.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
7.6 38.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
7.5 900.8 REACTOME TRANSLATION Genes involved in Translation
7.5 29.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
7.4 73.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
7.4 51.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
7.2 7.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
7.2 72.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
7.2 36.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
7.2 7.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
7.2 71.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
7.2 271.8 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
7.1 77.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
7.1 7.1 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
7.0 77.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
7.0 530.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
6.9 27.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
6.9 110.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
6.9 179.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
6.9 68.6 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
6.8 191.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
6.7 777.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
6.7 53.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
6.6 106.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
6.6 604.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
6.5 71.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
6.5 51.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
6.4 6.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
6.2 43.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
6.1 61.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
6.1 36.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
6.0 144.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
5.9 41.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
5.9 17.6 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
5.6 16.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
5.6 61.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
5.6 33.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
5.6 111.5 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
5.6 61.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
5.5 60.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
5.5 93.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
5.4 43.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
5.4 135.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
5.4 48.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
5.4 225.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
5.3 42.8 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
5.3 73.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
5.2 26.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
5.2 327.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
5.1 15.4 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
5.1 127.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
5.1 71.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
5.1 35.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
5.0 55.5 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
5.0 34.7 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
4.9 14.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.8 58.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
4.7 52.0 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
4.7 9.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
4.6 13.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
4.5 184.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
4.4 8.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
4.4 175.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
4.1 66.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
4.1 49.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
4.0 67.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
3.9 74.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
3.8 3.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
3.8 57.0 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
3.8 26.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
3.8 71.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
3.8 33.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
3.7 138.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
3.7 11.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
3.6 21.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
3.6 39.6 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
3.6 49.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
3.5 20.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
3.4 13.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
3.4 13.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
3.4 44.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
3.4 71.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
3.4 23.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
3.3 3.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
3.3 16.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
3.2 9.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
3.2 35.3 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
3.2 19.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
3.1 44.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
3.1 37.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
3.1 6.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
3.1 3.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.0 304.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
2.9 23.5 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
2.9 17.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
2.8 13.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
2.8 16.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
2.7 13.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
2.7 38.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
2.7 21.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.6 150.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
2.5 25.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
2.4 2.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
2.4 33.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
2.4 30.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
2.3 6.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
2.3 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
2.2 8.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.9 14.8 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
1.8 26.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.8 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.8 67.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.6 8.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
1.5 52.3 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
1.4 28.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
1.4 6.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.3 2.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.3 1.3 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
1.1 1.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
1.1 17.6 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport
1.1 2.2 REACTOME CELL CYCLE MITOTIC Genes involved in Cell Cycle, Mitotic
1.0 12.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.0 3.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
1.0 2.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
1.0 1.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.9 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.8 9.9 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.8 3.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.8 0.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.8 1.6 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.8 3.1 REACTOME DEFENSINS Genes involved in Defensins
0.7 0.7 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.7 10.6 REACTOME PLATELET HOMEOSTASIS Genes involved in Platelet homeostasis
0.7 7.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 21.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 12.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.5 1.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.4 5.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.3 2.4 REACTOME METABOLISM OF PROTEINS Genes involved in Metabolism of proteins
0.3 4.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.3 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.3 3.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.1 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.1 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events