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ENCODE: ATAC-seq of different tissues during embryonic development

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tbx3

Z-value: 0.98

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Transcription factors associated with Tbx3

Gene Symbol	Gene ID	Gene Info
Tbx3 Ensembl NCBI MGI UniProt	ENSMUSG00000018604.12	Tbx3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Tbx3	chr5_119670248_119671090	0	0.930045	-0.40	2.4e-03	Click!
Tbx3	chr5_119667698_119667879	2881	0.188694	-0.33	1.4e-02	Click!
Tbx3	chr5_119670018_119670217	552	0.618637	-0.24	8.1e-02	Click!
Tbx3	chr5_119667520_119667683	3068	0.182985	-0.24	8.1e-02	Click!
Tbx3	chr5_119680417_119680568	243	0.901478	-0.19	1.6e-01	Click!

Activity of the Tbx3 motif across conditions

Conditions sorted by the z-value of the Tbx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_104841712_104841954	2.22	Matr3-ps2	matrin 3, pseudogene 2	4540	0.11
chr16_81223847_81224195	1.82	Ncam2	neural cell adhesion molecule 2	23264	0.21
chr10_88046526_88046677	1.70	Gm48307	predicted gene, 48307	8376	0.16
chr1_128805866_128806034	1.61	Gm26686	predicted gene, 26686	31529	0.19
chr8_14992197_14993325	1.57	Arhgef10	Rho guanine nucleotide exchange factor (GEF) 10	2402	0.19
chr17_37002377_37003267	1.51	Zfp57	zinc finger protein 57	152	0.89
chr15_16311782_16311933	1.50	Gm6479	predicted gene 6479	103904	0.08
chr4_128715231_128715603	1.45	Phc2	polyhomeotic 2	5253	0.21
chr2_74711743_74712019	1.44	Hoxd3	homeobox D3	46	0.39
chr1_161689166_161689317	1.42	Gm37638	predicted gene, 37638	24464	0.16
chr9_16437769_16438174	1.41	Gm48726	predicted gene, 48726	2576	0.4
chr11_11113745_11113896	1.41	Vwc2	von Willebrand factor C domain containing 2	403	0.89
chr14_68981312_68981674	1.38	Stc1	stanniocalcin 1	47745	0.13
chr13_110115255_110115618	1.36	Rab3c	RAB3C, member RAS oncogene family	164714	0.04
chr5_140580109_140580299	1.32	Grifin	galectin-related inter-fiber protein	15133	0.11
chr8_26385143_26385305	1.28	Gm31898	predicted gene, 31898	50489	0.1
chr7_84403485_84403681	1.26	Arnt2	aryl hydrocarbon receptor nuclear translocator 2	6300	0.18
chr13_84344679_84345030	1.24	Gm26927	predicted gene, 26927	4741	0.26
chr4_58501073_58501357	1.24	Lpar1	lysophosphatidic acid receptor 1	1812	0.36
chr3_80878660_80878837	1.24	Glrb	glycine receptor, beta subunit	21493	0.21
chr4_22835459_22835658	1.22	Gm24078	predicted gene, 24078	88427	0.09
chr19_18888764_18889099	1.22	Trpm6	transient receptor potential cation channel, subfamily M, member 6	48294	0.16
chr11_18746571_18746722	1.21	Gm23093	predicted gene, 23093	7951	0.18
chr2_107344929_107345116	1.21	Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	53627	0.17
chr10_36555670_36555833	1.18	Hs3st5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	48344	0.16
chr13_10394442_10394746	1.17	Chrm3	cholinergic receptor, muscarinic 3, cardiac	33747	0.18
chr17_40731448_40731599	1.16	Esp1	exocrine gland secreted peptide 1	4403	0.19
chr2_141013562_141013766	1.16	Macrod2	mono-ADP ribosylhydrolase 2	10398	0.27
chr7_98354277_98354937	1.16	Tsku	tsukushi, small leucine rich proteoglycan	5472	0.19
chr7_89941710_89941882	1.15	Hikeshi	heat shock protein nuclear import factor	592	0.67
chr13_24656992_24657522	1.13	Ripor2	RHO family interacting cell polarization regulator 2	15682	0.19
chr9_75609468_75609796	1.12	Tmod2	tropomodulin 2	1443	0.33
chr2_15526355_15526523	1.12	Malrd1	MAM and LDL receptor class A domain containing 1	40	0.98
chr19_15827405_15827866	1.09	Gm50348	predicted gene, 50348	24577	0.22
chr18_88785266_88785620	1.09	Socs6	suppressor of cytokine signaling 6	26952	0.17
chr1_9578986_9579226	1.09	Gm6161	predicted gene 6161	4558	0.15
chr14_110047924_110048075	1.08	Gm24369	predicted gene, 24369	96600	0.08
chr14_101353078_101353291	1.07	Hspd1-ps5	heat shock protein 1 (chaperonin), pseudogene 5	9640	0.26
chr14_105861018_105861197	1.06	Gm48970	predicted gene, 48970	1394	0.47
chr18_60065037_60065286	1.04	Gm23576	predicted gene, 23576	109156	0.06
chr9_88712726_88712877	1.04	Mthfsl	5, 10-methenyltetrahydrofolate synthetase-like	3259	0.13
chr3_142711501_142711652	1.03	Kyat3	kynurenine aminotransferase 3	10482	0.13
chr7_107567693_107568007	1.02	Olfml1	olfactomedin-like 1	84	0.97
chr7_109082988_109083506	1.00	Ric3	RIC3 acetylcholine receptor chaperone	58	0.97
chr5_146289523_146289857	1.00	Cdk8	cyclin-dependent kinase 8	3514	0.21
chr9_102964862_102965013	0.99	Slco2a1	solute carrier organic anion transporter family, member 2a1	23775	0.15
chr15_57340524_57340684	0.99	Gm49229	predicted gene, 49229	7145	0.26
chr1_41605098_41605443	0.98	Gm28634	predicted gene 28634	75727	0.12
chr13_12565275_12566471	0.97	Ero1lb	ERO1-like beta (S. cerevisiae)	1	0.97
chr4_54944853_54945484	0.97	Zfp462	zinc finger protein 462	120	0.98
chr2_168677406_168677667	0.96	Atp9a	ATPase, class II, type 9A	7190	0.21
chr9_22049819_22050263	0.95	Elavl3	ELAV like RNA binding protein 3	1969	0.15
chr9_108949194_108950203	0.95	Gm37284	predicted gene, 37284	843	0.34
chr5_106926127_106926590	0.95	Hfm1	HFM1, ATP-dependent DNA helicase homolog	37	0.97
chrY_90738856_90739007	0.95	Mid1-ps1	midline 1, pseudogene 1	14126	0.18
chr1_130508576_130508872	0.94	Gm37283	predicted gene, 37283	34981	0.1
chr15_8865676_8865862	0.93	Gm5043	predicted gene 5043	48715	0.14
chr17_91657643_91657830	0.92	Gm15403	predicted gene 15403	9343	0.23
chr12_14089126_14089342	0.92	Gm48482	predicted gene, 48482	41414	0.15
chr12_13706665_13706816	0.92	Gm35890	predicted gene, 35890	37887	0.13
chr10_25253123_25253288	0.91	Gm7791	predicted gene 7791	1705	0.33
chr3_121700295_121700994	0.91	Gm43608	predicted gene 43608	9602	0.11
chr5_99129238_99129568	0.91	Gm43251	predicted gene 43251	42018	0.17
chr18_46922656_46922911	0.90	Arl14epl	ADP-ribosylation factor-like 14 effector protein-like	968	0.42
chr13_83985066_83985623	0.90	Gm4241	predicted gene 4241	2647	0.28
chr1_118776552_118777195	0.88	Gm28467	predicted gene 28467	33263	0.18
chr10_94622408_94622559	0.88	Gm48657	predicted gene, 48657	1943	0.25
chr3_38568713_38568864	0.88	Gm7824	predicted gene 7824	10120	0.18
chr11_99071812_99072098	0.87	Tns4	tensin 4	1909	0.25
chr2_61711466_61712232	0.86	Psmd14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	58	0.97
chr1_167547345_167547544	0.86	Rxrg	retinoid X receptor gamma	50940	0.14
chr4_14274144_14274295	0.86	Gm24908	predicted gene, 24908	34601	0.18
chr4_8850481_8851398	0.86	Chd7	chromodomain helicase DNA binding protein 7	4292	0.33
chr10_10557089_10557511	0.86	Rab32	RAB32, member RAS oncogene family	881	0.63
chr2_136051128_136051415	0.85	Lamp5	lysosomal-associated membrane protein family, member 5	968	0.6
chr13_73604216_73604826	0.85	Clptm1l	CLPTM1-like	515	0.77
chr1_130486360_130486516	0.85	Gm37283	predicted gene, 37283	12695	0.12
chr1_36071309_36071789	0.85	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	3149	0.19
chr10_22460817_22461194	0.85	Gm26585	predicted gene, 26585	7485	0.2
chr5_65130380_65130533	0.83	Klhl5	kelch-like 5	619	0.69
chr16_72088914_72089089	0.83	8030451O07Rik	RIKEN cDNA 8030451O07 gene	145301	0.04
chr11_88356603_88356961	0.82	Gm15893	predicted gene 15893	491	0.76
chr3_149184118_149184269	0.82	Gm42647	predicted gene 42647	26078	0.19
chr4_32860595_32860784	0.82	Ankrd6	ankyrin repeat domain 6	6	0.98
chr1_163313005_163313156	0.81	Prrx1	paired related homeobox 1	588	0.73
chr2_25628698_25629047	0.81	Fcna	ficolin A	842	0.28
chr6_6216492_6217324	0.81	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	210	0.95
chrX_111462568_111463018	0.81	Rps6ka6	ribosomal protein S6 kinase polypeptide 6	154	0.98
chr10_90494847_90495201	0.81	Gm22602	predicted gene, 22602	44114	0.18
chr3_56698198_56698780	0.81	Gm2622	predicted gene 2622	130298	0.06
chr12_85104881_85105032	0.81	Prox2	prospero homeobox 2	1475	0.25
chr12_4715736_4715911	0.81	Itsn2	intersectin 2	3474	0.14
chr14_14349604_14349813	0.81	Il3ra	interleukin 3 receptor, alpha chain	87	0.94
chr1_54850208_54850359	0.79	Ankrd44	ankyrin repeat domain 44	34428	0.16
chr5_27205920_27206071	0.79	Gm43776	predicted gene 43776	10040	0.22
chr18_52767530_52767965	0.79	Sncaip	synuclein, alpha interacting protein (synphilin)	37	0.98
chr7_29000909_29001719	0.78	Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	228	0.87
chr10_14977358_14977509	0.78	Gm23892	predicted gene, 23892	7237	0.25
chr1_133362506_133362657	0.78	Etnk2	ethanolamine kinase 2	991	0.44
chr3_154700810_154700968	0.78	Erich3	glutamate rich 3	10219	0.19
chr11_12857943_12858094	0.77	Gm12003	predicted gene 12003	79920	0.11
chr1_172203581_172203997	0.77	Pea15a	phosphoprotein enriched in astrocytes 15A	2908	0.13
chr8_94322161_94322312	0.77	C78859	expressed sequence C78859	78	0.94
chr17_21449784_21450734	0.76	Gm49691	predicted gene, 49691	8	0.6
chr6_114846251_114846445	0.76	Atg7	autophagy related 7	9803	0.19
chr6_48440397_48440548	0.75	Zfp467	zinc finger protein 467	3564	0.13
chr6_125082869_125083152	0.75	2010008C14Rik	RIKEN cDNA 2010008C14 gene	427	0.62
chr8_33115373_33115544	0.74	Gm45587	predicted gene 45587	59367	0.14
chr7_55910995_55911146	0.73	Cyfip1	cytoplasmic FMR1 interacting protein 1	2698	0.18
chr3_129554328_129554790	0.73	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	2179	0.27
chr6_64743195_64743391	0.73	Atoh1	atonal bHLH transcription factor 1	14168	0.26
chr17_87352856_87353104	0.72	0610012D04Rik	RIKEN cDNA 0610012D04 gene	11482	0.14
chr11_24126288_24126478	0.72	Gm12064	predicted gene 12064	10978	0.15
chr10_93521222_93521373	0.72	Amdhd1	amidohydrolase domain containing 1	18736	0.12
chr15_37597710_37597861	0.72	Gm24833	predicted gene, 24833	5749	0.21
chr9_102181344_102181531	0.71	Gm37945	predicted gene, 37945	8699	0.19
chr9_77419937_77420114	0.71	5730403I07Rik	RIKEN cDNA 5730403I07 gene	20607	0.16
chr10_39109575_39109751	0.71	Lama4	laminin, alpha 4	3882	0.19
chr9_34488623_34489109	0.70	Kirrel3	kirre like nephrin family adhesion molecule 3	38	0.98
chr10_21449143_21449294	0.70	Gm48386	predicted gene, 48386	3582	0.19
chr2_32547496_32547647	0.70	Fam102a	family with sequence similarity 102, member A	7381	0.09
chr13_83729640_83730023	0.70	Gm26803	predicted gene, 26803	249	0.86
chr4_84157986_84158137	0.69	Gm12414	predicted gene 12414	27772	0.21
chr6_6463850_6464144	0.69	Gm20685	predicted gene 20685	19025	0.19
chr2_157458372_157458814	0.68	Src	Rous sarcoma oncogene	1508	0.38
chr3_57424511_57424662	0.68	Tm4sf4	transmembrane 4 superfamily member 4	728	0.72
chr3_132539917_132540068	0.67	Gm25307	predicted gene, 25307	2327	0.37
chr3_30445595_30445780	0.67	Gm37024	predicted gene, 37024	42739	0.13
chr9_107430531_107430726	0.67	Gm17141	predicted gene 17141	61	0.95
chr12_3364588_3366025	0.66	Kif3c	kinesin family member 3C	116	0.94
chr17_47877482_47878031	0.66	Foxp4	forkhead box P4	1197	0.37
chr12_117158949_117159233	0.65	Gm10421	predicted gene 10421	7440	0.3
chr2_58361366_58361644	0.65	Acvr1c	activin A receptor, type IC	3610	0.26
chr16_55435552_55435703	0.65	Mir5118	microRNA 5118	59104	0.15
chr3_79818299_79818691	0.65	Gm26420	predicted gene, 26420	16438	0.17
chr1_71634479_71634636	0.65	Fn1	fibronectin 1	6731	0.2
chr10_52742516_52742678	0.65	Gm47624	predicted gene, 47624	48759	0.11
chr13_12650037_12651101	0.65	Gpr137b-ps	G protein-coupled receptor 137B, pseudogene	181	0.91
chr17_57086976_57087480	0.64	Tubb4a	tubulin, beta 4A class IVA	554	0.53
chr1_144004773_144004978	0.64	Rgs2	regulator of G-protein signaling 2	714	0.79
chrX_23364636_23365493	0.64	Gm14523	predicted gene 14523	1	0.5
chr19_41850602_41851080	0.64	Frat2	frequently rearranged in advanced T cell lymphomas 2	2709	0.19
chr7_45773527_45773678	0.63	Lmtk3	lemur tyrosine kinase 3	10136	0.07
chr18_54171516_54171708	0.63	Gm8594	predicted gene 8594	140304	0.05
chr6_5725548_5725949	0.63	Dync1i1	dynein cytoplasmic 1 intermediate chain 1	15	0.99
chr10_92242897_92243148	0.63	Gm47124	predicted gene, 47124	15568	0.19
chr3_101350461_101350612	0.63	Igsf3	immunoglobulin superfamily, member 3	26547	0.12
chr8_123409990_123410480	0.62	Tubb3	tubulin, beta 3 class III	1189	0.21
chr10_76810009_76810204	0.62	Pcbp3	poly(rC) binding protein 3	6600	0.23
chr14_12337514_12337689	0.62	Gm24578	predicted gene, 24578	3697	0.15
chr10_121309797_121309948	0.62	Tbc1d30	TBC1 domain family, member 30	1317	0.38
chr10_81464661_81465630	0.61	Gm16105	predicted gene 16105	3986	0.08
chr17_42905070_42905221	0.61	Cd2ap	CD2-associated protein	28480	0.23
chr14_39471742_39471933	0.60	Nrg3	neuregulin 3	829	0.77
chr12_33014141_33014292	0.59	Gm24922	predicted gene, 24922	14206	0.14
chr9_74861539_74862008	0.59	Onecut1	one cut domain, family member 1	148	0.94
chr11_87591342_87592719	0.59	Mtmr4	myotubularin related protein 4	132	0.94
chr7_46422213_46422380	0.59	Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	384	0.84
chr4_147084216_147084367	0.59	Gm13160	predicted gene 13160	2693	0.16
chr3_99253152_99253469	0.59	Tbx15	T-box 15	450	0.79
chr3_109496606_109496769	0.59	Vav3	vav 3 oncogene	1903	0.49
chr9_69760785_69760967	0.59	Foxb1	forkhead box B1	64	0.77
chr11_70023587_70023764	0.59	Dlg4	discs large MAGUK scaffold protein 4	245	0.79
chr2_104864646_104864797	0.58	Ccdc73	coiled-coil domain containing 73	3084	0.19
chr6_126646041_126646221	0.58	Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	253	0.93
chr7_4921936_4922215	0.58	Nat14	N-acetyltransferase 14	47	0.93
chr2_137087714_137088012	0.58	Jag1	jagged 1	1914	0.46
chr7_107690580_107690754	0.58	Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	25356	0.14
chr7_45361179_45361983	0.58	Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	241	0.77
chr13_18338162_18338313	0.58	Pou6f2	POU domain, class 6, transcription factor 2	43802	0.19
chr4_9245561_9245857	0.58	Clvs1	clavesin 1	23584	0.19
chr13_13393240_13394314	0.58	Gpr137b	G protein-coupled receptor 137B	153	0.93
chr9_56841988_56842139	0.58	Odf3l1	outer dense fiber of sperm tails 3-like 1	9900	0.14
chr12_104746683_104746834	0.57	Dicer1	dicer 1, ribonuclease type III	5194	0.24
chr2_59158254_59158419	0.57	Ccdc148	coiled-coil domain containing 148	2198	0.27
chr14_121749717_121749868	0.57	Dock9	dedicator of cytokinesis 9	10931	0.24
chr9_103211367_103211518	0.57	Trf	transferrin	564	0.73
chr1_118873427_118873578	0.57	Gm28467	predicted gene 28467	63366	0.11
chr3_66166936_66167158	0.57	Gm37330	predicted gene, 37330	24198	0.13
chr2_75988830_75989059	0.57	Ttc30a1	tetratricopeptide repeat domain 30A1	6977	0.17
chr13_114462648_114462799	0.56	Fst	follistatin	3772	0.18
chr19_59470019_59470513	0.56	Emx2	empty spiracles homeobox 2	7464	0.17
chr19_29641108_29641414	0.56	Ermp1	endoplasmic reticulum metallopeptidase 1	1698	0.39
chr12_60652331_60652482	0.56	Gm23059	predicted gene, 23059	83092	0.1
chr1_57862082_57862411	0.56	Spats2l	spermatogenesis associated, serine-rich 2-like	16675	0.22
chr13_86602141_86602292	0.56	Gm25700	predicted gene, 25700	123716	0.06
chr3_146333404_146333566	0.56	Gm43334	predicted gene 43334	9065	0.17
chr5_100572149_100572573	0.56	Plac8	placenta-specific 8	116	0.95
chr7_25132999_25133993	0.56	Pou2f2	POU domain, class 2, transcription factor 2	984	0.41
chr10_123678311_123678758	0.55	Gm19169	predicted gene, 19169	94946	0.09
chr10_26373351_26373502	0.55	L3mbtl3	L3MBTL3 histone methyl-lysine binding protein	530	0.74
chr7_83813950_83814479	0.55	Gm39043	predicted gene, 39043	493	0.69
chr3_61315135_61315286	0.55	Gm19901	predicted gene, 19901	13983	0.17
chr3_132129979_132130143	0.55	Dkk2	dickkopf WNT signaling pathway inhibitor 2	44769	0.17
chr19_35152377_35152646	0.54	Gm50140	predicted gene, 50140	22983	0.19
chr1_104425392_104425677	0.54	Gm29140	predicted gene 29140	45882	0.17
chrX_118596164_118596357	0.54	Gm7485	predicted gene 7485	102643	0.08
chr8_4588392_4588579	0.54	Zfp958	zinc finger protein 958	24682	0.12
chr8_49313570_49313729	0.54	4930555F03Rik	RIKEN cDNA 4930555F03 gene	57237	0.14
chr4_28784019_28784205	0.54	Epha7	Eph receptor A7	29019	0.19

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0030070	insulin processing(GO:0030070)
0.3	0.8	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	1.0	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.2	0.7	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.2	0.6	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.2	0.5	GO:1903232	melanosome assembly(GO:1903232)
0.2	0.7	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.2	1.2	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1	0.6	GO:0007412	axon target recognition(GO:0007412)
0.1	0.4	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1	0.4	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.1	0.6	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.7	GO:0046618	drug export(GO:0046618)
0.1	0.4	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1	0.3	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.5	GO:0097460	ferrous iron import into cell(GO:0097460)
0.1	0.6	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	1.0	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.5	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	0.4	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.8	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.4	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.4	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.8	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.1	0.5	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.3	GO:0072069	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.1	0.3	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.5	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.1	0.3	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1	0.3	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	0.2	GO:0002930	trabecular meshwork development(GO:0002930)
0.1	0.3	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.2	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.1	0.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.9	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.4	GO:1902837	amino acid import into cell(GO:1902837)
0.1	0.1	GO:0010535	positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.1	0.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.2	GO:0060178	regulation of exocyst localization(GO:0060178)
0.1	0.5	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	0.1	GO:2000981	negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1	0.4	GO:0021764	amygdala development(GO:0021764)
0.1	0.2	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.2	GO:0035262	gonad morphogenesis(GO:0035262)
0.1	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.1	0.3	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	0.2	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.2	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.1	0.2	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.3	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.3	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.5	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1	0.4	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.1	GO:2001025	positive regulation of response to drug(GO:2001025)
0.1	0.4	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1	0.2	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.1	0.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.3	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.1	GO:0051593	response to folic acid(GO:0051593)
0.1	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.4	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.4	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.0	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.3	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.4	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.2	GO:0046959	habituation(GO:0046959)
0.0	0.2	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.2	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.2	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.2	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.2	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.3	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0035993	deltoid tuberosity development(GO:0035993)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.3	GO:0035989	tendon development(GO:0035989)
0.0	0.7	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0	0.4	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.8	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.5	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.3	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0	0.2	GO:0044849	estrous cycle(GO:0044849)
0.0	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.5	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.4	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0070268	cornification(GO:0070268)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.3	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.6	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.0	GO:2000978	negative regulation of forebrain neuron differentiation(GO:2000978)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.3	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.3	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	1.0	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.4	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.3	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.1	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.9	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.6	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.0	0.3	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.2	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.2	GO:0060536	cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.2	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.0	0.0	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.8	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.2	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.8	GO:0072384	organelle transport along microtubule(GO:0072384)
0.0	0.0	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.3	GO:0016082	synaptic vesicle priming(GO:0016082)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.7	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.3	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0051204	protein insertion into mitochondrial membrane(GO:0051204)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.1	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.2	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.0	GO:0033024	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) negative regulation of mast cell apoptotic process(GO:0033026)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.2	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0	0.1	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.0	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.0	0.1	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0046909	intermembrane transport(GO:0046909)
0.0	0.2	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:1904393	positive regulation of postsynaptic membrane organization(GO:1901628) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.0	GO:1904192	skeletal muscle hypertrophy(GO:0014734) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.0	GO:0100012	cardiac cell fate determination(GO:0060913) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.3	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.0	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.0	0.1	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0060066	oviduct development(GO:0060066)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.3	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.0	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.0	0.1	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.3	GO:1901381	positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0	0.0	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.0	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.0	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0	0.0	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.0	GO:0035822	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.0	0.0	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.0	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.2	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.0	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0	0.0	GO:0061055	myotome development(GO:0061055)
0.0	0.0	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.0	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.0	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0060279	positive regulation of ovulation(GO:0060279)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.3	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.0	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.0	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.0	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0043031	negative regulation of macrophage activation(GO:0043031)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.7	GO:0097433	dense body(GO:0097433)
0.1	1.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.6	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.1	0.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	0.6	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.3	GO:0033269	internode region of axon(GO:0033269)
0.1	0.5	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.1	1.0	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0044308	axonal spine(GO:0044308)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.2	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1	0.5	GO:0036156	inner dynein arm(GO:0036156)
0.1	1.7	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.6	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.5	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.4	GO:0032797	SMN complex(GO:0032797)
0.0	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.7	GO:0030057	desmosome(GO:0030057)
0.0	0.3	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.8	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.3	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.9	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0097386	glial cell projection(GO:0097386)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	1.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.0	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.0	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.3	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0045503	dynein light chain binding(GO:0045503)
0.2	0.8	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	0.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.2	0.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.2	0.5	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.2	1.0	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.2	0.5	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.8	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	0.4	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.4	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.4	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1	1.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.4	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.4	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.3	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.1	0.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.4	GO:0042731	PH domain binding(GO:0042731)
0.1	0.4	GO:0071253	connexin binding(GO:0071253)
0.1	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	0.4	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.2	GO:0045340	mercury ion binding(GO:0045340)
0.1	0.3	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.2	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.2	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.3	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.3	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	1.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0038100	nodal binding(GO:0038100)
0.0	0.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	1.0	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.4	GO:0016594	glycine binding(GO:0016594)
0.0	0.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.3	GO:0070694	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.9	GO:0019894	kinesin binding(GO:0019894)
0.0	0.5	GO:0004119	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.8	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.3	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.0	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.3	GO:0005186	pheromone activity(GO:0005186)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.0	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.2	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.2	GO:0019825	oxygen binding(GO:0019825)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.0	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.2	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.0	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.0	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.0	GO:0003905	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.1	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	1.7	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.8	ST GA12 PATHWAY	G alpha 12 Pathway
0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.4	PID REELIN PATHWAY	Reelin signaling pathway
0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.7	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.9	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.4	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle