Project
ENCODE: ATAC-seq of different tissues during embryonic development
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tbx4

Z-value: 0.51

Motif logo

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Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000094.6 Tbx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
Tbx4chr11_85917179_85917330204890.1633930.454.9e-04Click!
Tbx4chr11_85917416_85917567207260.1629770.331.4e-02Click!
Tbx4chr11_85918029_85918180213390.1618880.302.6e-02Click!
Tbx4chr11_85876616_8587678797210.1531800.293.5e-02Click!
Tbx4chr11_85888793_8588894411950.446321-0.221.0e-01Click!

Activity of the Tbx4 motif across conditions

Conditions sorted by the z-value of the Tbx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_77207847_77208140 3.03 Spink2
serine peptidase inhibitor, Kazal type 2
3212
0.19
chr7_24316125_24316983 2.68 Zfp94
zinc finger protein 94
28
0.92
chr6_55580187_55580359 2.44 Gm44352
predicted gene, 44352
46767
0.15
chr1_6730002_6730187 2.30 St18
suppression of tumorigenicity 18
7
0.99
chr16_33605736_33606716 2.15 Slc12a8
solute carrier family 12 (potassium/chloride transporters), member 8
9599
0.26
chr19_53449312_53449723 2.08 Mirt1
myocardial infarction associated transcript 1
1974
0.25
chr15_66286727_66287219 2.04 Gm27242
predicted gene 27242
56
0.82
chr5_22262595_22262780 2.04 Gm16113
predicted gene 16113
18895
0.17
chr1_85588537_85589247 2.02 Sp110
Sp110 nuclear body protein
299
0.81
chr10_81472309_81472908 2.01 Celf5
CUGBP, Elav-like family member 5
394
0.64
chr9_121606831_121606982 2.00 Lyzl4os
lysozyme-like 4, opposite strand
4062
0.16
chr7_30291145_30292058 1.91 Clip3
CAP-GLY domain containing linker protein 3
127
0.89
chr3_145890165_145890867 1.89 Rpl36a-ps2
ribosomal protein L36A, pseudogene 2
11496
0.18
chr12_3238767_3239202 1.89 Rab10os
RAB10, member RAS oncogene family, opposite strand
2373
0.24
chr13_71690114_71690396 1.88 Gm47812
predicted gene, 47812
65227
0.12
chr3_52784594_52784745 1.85 Gm30292
predicted gene, 30292
13116
0.19
chr4_65838866_65839193 1.84 Trim32
tripartite motif-containing 32
233780
0.02
chr3_89233602_89234072 1.84 Muc1
mucin 1, transmembrane
2366
0.09
chr15_75566838_75567525 1.83 Ly6h
lymphocyte antigen 6 complex, locus H
35
0.96
chr9_58111541_58111738 1.81 Ccdc33
coiled-coil domain containing 33
2721
0.19
chr13_6307436_6307642 1.80 Gm35615
predicted gene, 35615
12825
0.23
chr9_61101873_61102054 1.80 4933433G08Rik
RIKEN cDNA 4933433G08 gene
3422
0.18
chr8_52571597_52571748 1.79 Gm45673
predicted gene 45673
16958
0.29
chr12_109010051_109010202 1.79 Wdr25
WD repeat domain 25
10676
0.14
chr1_153641449_153641897 1.78 Rgs8
regulator of G-protein signaling 8
11352
0.15
chr3_139885937_139886924 1.78 Gm43678
predicted gene 43678
73666
0.11
chr4_136786990_136787145 1.77 Ephb2
Eph receptor B2
48776
0.12
chr13_107542096_107542247 1.76 Gm32004
predicted gene, 32004
23152
0.2
chr18_60925808_60926037 1.73 Camk2a
calcium/calmodulin-dependent protein kinase II alpha
197
0.92
chr5_15850216_15850406 1.72 Gm42453
predicted gene 42453
19936
0.14
chr17_52602043_52602770 1.71 Gm27217
predicted gene 27217
254
0.55
chr6_55920965_55921278 1.71 Itprid1
ITPR interacting domain containing 1
34296
0.21
chr14_79773765_79773944 1.71 Pcdh8
protocadherin 8
2542
0.22
chr9_94610676_94610827 1.71 Gm39404
predicted gene, 39404
18555
0.17
chr17_65961618_65962124 1.71 Ankrd12
ankyrin repeat domain 12
10521
0.14
chr8_71670876_71671939 1.70 Unc13a
unc-13 homolog A
329
0.75
chr7_51662439_51662822 1.70 Gm45072
predicted gene 45072
30905
0.14
chr19_14436131_14436458 1.67 Tle4
transducin-like enhancer of split 4
159245
0.04
chr5_150905805_150906370 1.65 Gm43298
predicted gene 43298
23445
0.17
chr10_17203245_17203406 1.65 Gm25382
predicted gene, 25382
86521
0.09
chr4_25408022_25408173 1.64 Gm11894
predicted gene 11894
11252
0.22
chr3_105530950_105531126 1.63 Gm43847
predicted gene 43847
28131
0.18
chr12_44329338_44330111 1.63 Nrcam
neuronal cell adhesion molecule
474
0.8
chr12_26886622_26886951 1.62 4933409F18Rik
RIKEN cDNA 4933409F18 gene
51913
0.18
chr4_24966254_24966983 1.62 C230012O17Rik
RIKEN cDNA C230012O17 gene
2
0.49
chr11_98284318_98284581 1.60 Gm20644
predicted gene 20644
933
0.39
chr3_80878660_80878837 1.60 Glrb
glycine receptor, beta subunit
21493
0.21
chr1_171342895_171343046 1.59 Nit1
nitrilase 1
1497
0.15
chr13_104914342_104914493 1.59 Gm4938
predicted pseudogene 4938
4363
0.27
chr7_129664007_129664606 1.59 Gm33248
predicted gene, 33248
3099
0.26
chr2_152048577_152049360 1.58 AA387200
expressed sequence AA387200
27840
0.11
chr18_72949026_72949703 1.56 Gm31908
predicted gene, 31908
28274
0.23
chr3_17319141_17319707 1.56 Gm30340
predicted gene, 30340
15001
0.21
chr9_44721587_44722104 1.54 Phldb1
pleckstrin homology like domain, family B, member 1
421
0.66
chr15_10421870_10422041 1.53 Dnajc21
DnaJ heat shock protein family (Hsp40) member C21
28037
0.15
chr17_34398184_34398665 1.53 Gm15320
predicted gene 15320
262
0.58
chr16_91962945_91963627 1.52 Gm27773
predicted gene, 27773
19138
0.1
chr13_93072907_93073474 1.50 Gm4814
predicted gene 4814
114
0.97
chr16_35592451_35593042 1.50 Gm5963
predicted pseudogene 5963
19190
0.18
chr9_117873123_117873274 1.50 Gm26614
predicted gene, 26614
54
0.9
chr8_45110316_45110467 1.50 Gm30504
predicted gene, 30504
90
0.97
chr16_44665571_44665978 1.50 Nepro
nucleolus and neural progenitor protein
58527
0.1
chr9_84032652_84032865 1.49 Bckdhb
branched chain ketoacid dehydrogenase E1, beta polypeptide
3082
0.26
chr18_26847440_26847591 1.49 Gm49976
predicted gene, 49976
70582
0.12
chr13_12503393_12503759 1.49 Edaradd
EDAR (ectodysplasin-A receptor)-associated death domain
16862
0.14
chr12_11455707_11456527 1.49 Rad51ap2
RAD51 associated protein 2
38
0.97
chr10_84415077_84415379 1.48 Nuak1
NUAK family, SNF1-like kinase, 1
22840
0.15
chr17_93201885_93202105 1.48 Adcyap1
adenylate cyclase activating polypeptide 1
81
0.97
chr2_154421692_154421847 1.47 Snta1
syntrophin, acidic 1
13670
0.15
chr13_15741859_15742225 1.47 Gm48408
predicted gene, 48408
28078
0.16
chr11_20988071_20988283 1.45 Gm23681
predicted gene, 23681
50476
0.13
chr10_80145825_80146996 1.45 Midn
midnolin
1862
0.15
chr1_105843089_105843248 1.44 Tnfrsf11a
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
23298
0.17
chr17_80483292_80483614 1.44 Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
3000
0.29
chr13_112165997_112166183 1.44 Gm48802
predicted gene, 48802
5978
0.21
chr13_74010757_74011079 1.43 Tppp
tubulin polymerization promoting protein
1499
0.22
chr14_55115923_55116196 1.43 Jph4
junctophilin 4
507
0.61
chr1_5018013_5019021 1.43 Rgs20
regulator of G-protein signaling 20
218
0.93
chr6_6871537_6871723 1.43 Dlx6os1
distal-less homeobox 6, opposite strand 1
38
0.96
chr3_34659334_34659485 1.43 Sox2ot
SOX2 overlapping transcript (non-protein coding)
3373
0.14
chr1_56920700_56920851 1.42 Satb2
special AT-rich sequence binding protein 2
49065
0.13
chr15_85494388_85494565 1.42 7530416G11Rik
RIKEN cDNA 7530416G11 gene
8751
0.19
chr6_47239363_47240145 1.41 Cntnap2
contactin associated protein-like 2
4633
0.33
chr10_93275246_93275449 1.41 Elk3
ELK3, member of ETS oncogene family
35464
0.13
chr6_146387163_146387325 1.40 Itpr2
inositol 1,4,5-triphosphate receptor 2
9742
0.2
chr13_58544429_58544580 1.40 Gm3131
predicted gene 3131
1524
0.39
chr14_122450411_122450692 1.40 Gm5089
predicted gene 5089
564
0.66
chr1_41605849_41606032 1.39 Gm28634
predicted gene 28634
76397
0.12
chr2_109674717_109674868 1.38 Bdnf
brain derived neurotrophic factor
92
0.95
chr14_45388403_45389548 1.38 Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
14
0.96
chr12_27084297_27084457 1.37 Gm9866
predicted gene 9866
30618
0.25
chr4_154856178_154856666 1.37 Ttc34
tetratricopeptide repeat domain 34
222
0.91
chr5_90588819_90589267 1.37 Gm42109
predicted gene, 42109
14
0.97
chr12_27357279_27357647 1.36 Sox11
SRY (sex determining region Y)-box 11
14889
0.28
chr7_4995595_4996371 1.35 Zfp579
zinc finger protein 579
46
0.92
chr1_85279771_85280739 1.35 Gm16026
predicted pseudogene 16026
5148
0.14
chr1_74542776_74542947 1.35 Plcd4
phospholipase C, delta 4
27
0.95
chr9_121549119_121549291 1.35 Gm47095
predicted gene, 47095
13054
0.14
chr3_38887381_38887941 1.35 C230034O21Rik
RIKEN cDNA C230034O21 gene
598
0.52
chr6_48395472_48395677 1.35 Krba1
KRAB-A domain containing 1
12
0.67
chr14_108709180_108709331 1.35 Rpl27a-ps2
ribosomal protein L27A, pseudogene 2
16612
0.28
chr7_18926314_18927174 1.34 Nova2
NOVA alternative splicing regulator 2
856
0.42
chr15_37786426_37786599 1.34 Ncald
neurocalcin delta
5488
0.19
chr1_157439951_157440671 1.34 Cryzl2
crystallin zeta like 2
18266
0.12
chr8_97476861_97477019 1.33 Gm5913
predicted gene 5913
47830
0.17
chr15_83781833_83781984 1.33 Mpped1
metallophosphoesterase domain containing 1
1885
0.4
chr3_30452791_30452942 1.33 Gm37024
predicted gene, 37024
35560
0.14
chr18_68976284_68976447 1.32 4930546C10Rik
RIKEN cDNA 4930546C10 gene
24837
0.21
chr7_105787328_105788039 1.32 Dchs1
dachsous cadherin related 1
29
0.95
chr12_3891760_3892416 1.32 Dnmt3a
DNA methyltransferase 3A
344
0.86
chr2_19910475_19910626 1.32 Etl4
enhancer trap locus 4
770
0.63
chr7_25003802_25003953 1.31 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
2018
0.19
chr11_82387975_82388126 1.31 Gm38577
predicted gene, 38577
710
0.49
chr19_14240367_14240560 1.31 Gm26993
predicted gene, 26993
222092
0.02
chr17_15248499_15248674 1.31 Gm5091
predicted gene 5091
669
0.71
chr2_26153959_26154346 1.30 Tmem250-ps
transmembrane protein 250, pseudogene
13631
0.11
chr7_63668207_63668417 1.30 Otud7a
OTU domain containing 7A
17497
0.2
chr13_36736583_36736914 1.29 Nrn1
neuritin 1
1617
0.34
chr4_22973852_22974022 1.29 1700025O08Rik
RIKEN cDNA 1700025O08 gene
35502
0.23
chr1_163150570_163150773 1.28 Gm22434
predicted gene, 22434
32444
0.15
chr18_50034876_50035293 1.28 Tnfaip8
tumor necrosis factor, alpha-induced protein 8
4055
0.24
chr11_19554563_19554970 1.28 Gm12027
predicted gene 12027
73295
0.11
chr2_50044863_50045062 1.27 Lypd6
LY6/PLAUR domain containing 6
21467
0.27
chr18_56774889_56775040 1.27 Gm15345
predicted gene 15345
5247
0.22
chr7_141070009_141070863 1.27 B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
161
0.88
chr8_12214132_12214283 1.27 A230072I06Rik
RIKEN cDNA A230072I06 gene
64612
0.1
chr4_140103440_140103668 1.27 Gm13027
predicted gene 13027
28323
0.17
chr1_137378356_137378537 1.26 Gm23534
predicted gene, 23534
11199
0.24
chr1_85600326_85601326 1.26 Sp140
Sp140 nuclear body protein
123
0.9
chr4_117406049_117406200 1.26 Rnf220
ring finger protein 220
30667
0.13
chr10_26827294_26827613 1.26 Arhgap18
Rho GTPase activating protein 18
4851
0.26
chr4_46559322_46559634 1.26 Coro2a
coronin, actin binding protein 2A
6962
0.16
chr4_148327377_148327851 1.24 Gm13206
predicted gene 13206
20761
0.14
chr17_43952334_43952615 1.24 Rcan2
regulator of calcineurin 2
525
0.86
chr8_63530326_63530477 1.24 Gm18645
predicted gene, 18645
7479
0.25
chr2_32175074_32175462 1.23 Gm27805
predicted gene, 27805
2097
0.2
chr18_34089514_34089665 1.23 Gm24432
predicted gene, 24432
3856
0.19
chr3_89660407_89660568 1.23 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
2031
0.3
chr11_86807230_86808078 1.22 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
92
0.98
chr16_67617369_67617586 1.22 Cadm2
cell adhesion molecule 2
3016
0.33
chr10_125388906_125389759 1.21 Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
36
0.95
chr4_30268060_30268211 1.21 Gm11925
predicted gene 11925
74488
0.13
chr8_123514551_123514702 1.21 Dbndd1
dysbindin (dystrobrevin binding protein 1) domain containing 1
764
0.23
chr6_54785459_54785618 1.21 Znrf2
zinc and ring finger 2
31378
0.17
chr6_119341715_119341866 1.21 Cacna2d4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
9228
0.19
chr3_147064283_147064453 1.21 Gm29771
predicted gene, 29771
31816
0.21
chr5_148265155_148265692 1.20 Mtus2
microtubule associated tumor suppressor candidate 2
78
0.98
chr1_172203581_172203997 1.20 Pea15a
phosphoprotein enriched in astrocytes 15A
2908
0.13
chr2_24761902_24762681 1.20 Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
756
0.65
chr17_49966143_49966321 1.20 AC133946.1
oxidoreductase NAD-binding domain containing 1 (OXNAD1) pseudogene
6595
0.22
chr1_85489813_85490173 1.20 AC147806.1
novel protein
4851
0.14
chr12_112507366_112507590 1.20 Tmem179
transmembrane protein 179
3694
0.2
chr13_68997784_68997935 1.19 Gm48593
predicted gene, 48593
160
0.89
chr16_41258452_41258650 1.18 Gm47276
predicted gene, 47276
40774
0.18
chr5_112643537_112643881 1.18 4933415J04Rik
RIKEN cDNA 4933415J04 gene
3374
0.19
chr12_12904775_12904974 1.18 4930519A11Rik
RIKEN cDNA 4930519A11 gene
324
0.83
chr11_40601046_40601211 1.18 Gm12137
predicted gene 12137
11590
0.19
chr9_118476459_118476610 1.18 Eomes
eomesodermin
1678
0.28
chr1_132292340_132292811 1.18 Klhdc8a
kelch domain containing 8A
6051
0.12
chr3_33074496_33074647 1.17 Gm19445
predicted gene, 19445
1785
0.3
chr11_16831942_16832164 1.17 Egfros
epidermal growth factor receptor, opposite strand
1351
0.48
chr1_144151888_144152189 1.17 Rgs13
regulator of G-protein signaling 13
25237
0.22
chr9_89622321_89623673 1.16 Minar1
membrane integral NOTCH2 associated receptor 1
128
0.96
chr19_55424034_55424281 1.16 Vti1a
vesicle transport through interaction with t-SNAREs 1A
43143
0.18
chr4_20460440_20460613 1.16 Gm11873
predicted gene 11873
69430
0.13
chr6_6463850_6464144 1.15 Gm20685
predicted gene 20685
19025
0.19
chr10_81559146_81561402 1.15 Tle5
TLE family member 5, transcriptional modulator
770
0.38
chr3_143947996_143948150 1.14 Gm42707
predicted gene 42707
6325
0.24
chr13_54884713_54885019 1.14 Gm29431
predicted gene 29431
2604
0.21
chr19_23959939_23960407 1.14 Fam189a2
family with sequence similarity 189, member A2
16262
0.16
chr4_98578651_98578802 1.14 Gm22625
predicted gene, 22625
20861
0.18
chr6_107529026_107529193 1.13 Lrrn1
leucine rich repeat protein 1, neuronal
659
0.75
chr17_55971009_55971201 1.13 Shd
src homology 2 domain-containing transforming protein D
329
0.74
chr6_138581835_138581986 1.13 Lmo3
LIM domain only 3
58
0.96
chr1_85162433_85162707 1.12 Gm6264
predicted gene 6264
1707
0.22
chr14_55520440_55521261 1.12 Nrl
neural retina leucine zipper gene
417
0.62
chr10_77146904_77147516 1.12 Gm7775
predicted gene 7775
10110
0.18
chr1_42714883_42715034 1.12 Pantr2
POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2
1504
0.32
chr1_85613380_85613547 1.12 Gm10552
predicted gene 10552
1567
0.22
chr10_30343195_30343371 1.11 Gm4780
predicted gene 4780
29635
0.21
chr1_167119518_167119861 1.11 Gm17868
predicted gene, 17868
21466
0.19
chr8_84814005_84814224 1.11 Dand5
DAN domain family member 5, BMP antagonist
8709
0.08
chr2_49628188_49628339 1.11 Kif5c
kinesin family member 5C
8965
0.25
chr17_56020485_56020811 1.11 Gm16276
predicted gene 16276
6104
0.08
chr4_154855497_154855648 1.10 Ttc34
tetratricopeptide repeat domain 34
628
0.65
chr17_5286909_5287083 1.10 Gm29050
predicted gene 29050
101767
0.07
chr1_106629505_106629752 1.10 Gm37053
predicted gene, 37053
22758
0.19
chr3_101350461_101350612 1.10 Igsf3
immunoglobulin superfamily, member 3
26547
0.12
chr1_176987057_176987208 1.10 Sdccag8
serologically defined colon cancer antigen 8
10877
0.14
chr10_121830468_121830669 1.09 Gm48804
predicted gene, 48804
1490
0.42
chr1_85095587_85095804 1.09 Gm10553
predicted gene 10553
3817
0.11
chr2_76498827_76499126 1.09 Osbpl6
oxysterol binding protein-like 6
121
0.97
chr3_138784741_138784929 1.09 Tspan5
tetraspanin 5
1981
0.36
chr8_105320451_105321442 1.08 Lrrc29
leucine rich repeat containing 29
5313
0.07
chr6_53881319_53881470 1.08 Gm22910
predicted gene, 22910
9246
0.21
chr4_28227956_28228107 1.08 Gm11907
predicted gene 11907
125752
0.05
chr6_135376013_135376170 1.08 Emp1
epithelial membrane protein 1
8598
0.17
chr16_16931024_16931224 1.07 Gm46540
predicted gene, 46540
1737
0.22
chr3_7502758_7503252 1.07 Zc2hc1a
zinc finger, C2HC-type containing 1A
478
0.68
chr5_120195065_120195267 1.07 Rbm19
RNA binding motif protein 19
19441
0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.5 1.4 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.4 1.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.4 1.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.3 1.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 1.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.3 1.3 GO:0007412 axon target recognition(GO:0007412)
0.3 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.2 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.3 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 0.7 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.2 1.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 0.9 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.2 0.6 GO:0052490 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.2 1.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.4 GO:0048320 axial mesoderm formation(GO:0048320)
0.2 1.0 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 0.7 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2 1.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.5 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.2 0.5 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 2.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 0.6 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.8 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.5 GO:0032898 neurotrophin production(GO:0032898)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.7 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.4 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.4 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 0.6 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.8 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.8 GO:0098926 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.1 GO:0060482 lobar bronchus development(GO:0060482)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.5 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.6 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.4 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.1 GO:0061642 chemoattraction of axon(GO:0061642)
0.1 0.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.2 GO:0061205 paramesonephric duct development(GO:0061205)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.8 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.1 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.1 0.3 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.2 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.1 GO:0072221 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.1 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.1 0.2 GO:0042851 L-alanine metabolic process(GO:0042851)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.6 GO:0002176 male germ cell proliferation(GO:0002176)
0.1 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.2 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.5 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.0 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.1 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.0 0.1 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0071242 cellular response to ammonium ion(GO:0071242)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0072173 metanephric tubule morphogenesis(GO:0072173)
0.0 0.9 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:1902074 response to salt(GO:1902074)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.0 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.0 GO:0072051 juxtaglomerular apparatus development(GO:0072051)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0044838 cell quiescence(GO:0044838)
0.0 0.5 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0015819 lysine transport(GO:0015819)
0.0 0.0 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.0 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.0 GO:0060486 Clara cell differentiation(GO:0060486)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:1903276 regulation of sodium ion export(GO:1903273) regulation of sodium ion export from cell(GO:1903276)
0.0 0.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0045713 low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.0 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.7 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0036376 sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0003140 determination of left/right asymmetry in lateral mesoderm(GO:0003140)
0.0 0.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.0 GO:0030421 defecation(GO:0030421)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.0 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.0 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.0 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.0 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0015867 ATP transport(GO:0015867)
0.0 0.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:1903802 amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.0 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.0 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.0 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.0 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:2000520 regulation of immunological synapse formation(GO:2000520)
0.0 0.1 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0043194 axon initial segment(GO:0043194)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.7 GO:0042629 mast cell granule(GO:0042629)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.1 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0097413 Lewy body(GO:0097413)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 3.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.0 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.4 1.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 1.6 GO:0097001 ceramide binding(GO:0097001)
0.4 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 0.9 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 1.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 0.9 GO:0015189 arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.2 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 2.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.4 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1 0.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0003905 alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 1.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0043919 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0 0.0 GO:0004337 geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.0 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 0.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.0 REACTOME DNA REPLICATION Genes involved in DNA Replication
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma