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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Arid3a

Z-value: 1.10

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Transcription factors associated with Arid3a

Gene Symbol	Gene ID	Gene Info
Arid3a Ensembl NCBI MGI UniProt	ENSMUSG00000019564.6	Arid3a

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Arid3a	chr10_79937271_79937429	6926	0.061887	0.83	3.9e-02	Click!
Arid3a	chr10_79926721_79927086	140	0.861880	0.80	5.6e-02	Click!
Arid3a	chr10_79932814_79932968	2467	0.094376	0.76	8.1e-02	Click!
Arid3a	chr10_79928248_79928404	985	0.244518	0.74	9.3e-02	Click!
Arid3a	chr10_79928498_79928649	1232	0.186877	0.73	9.7e-02	Click!

Activity of the Arid3a motif across conditions

Conditions sorted by the z-value of the Arid3a motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_36537159_36537318	0.94	Ankrd23	ankyrin repeat domain 23	355	0.71
chr10_31644816_31644968	0.75	Gm8793	predicted gene 8793	5734	0.23
chr10_122384642_122385270	0.73	Gm36041	predicted gene, 36041	1936	0.39
chr7_113223800_113224075	0.70	Arntl	aryl hydrocarbon receptor nuclear translocator-like	10686	0.21
chr15_26353541_26353723	0.69	Marchf11	membrane associated ring-CH-type finger 11	34087	0.23
chrX_11018346_11018497	0.67	Gm14485	predicted gene 14485	2586	0.39
chrX_38473317_38473492	0.60	Gm7598	predicted gene 7598	3057	0.24
chr5_8962552_8962757	0.60	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	4102	0.15
chr18_20931708_20931938	0.57	Rnf125	ring finger protein 125	12802	0.2
chr1_88760195_88760369	0.57	Platr5	pluripotency associated transcript 5	5328	0.21
chr6_128504140_128504367	0.56	Pzp	PZP, alpha-2-macroglobulin like	9030	0.09
chr18_20943771_20943971	0.56	Rnf125	ring finger protein 125	754	0.69
chr14_100324093_100324244	0.53	Gm41231	predicted gene, 41231	38003	0.15
chr6_24296762_24296913	0.49	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	128745	0.05
chr2_154585868_154586214	0.49	E2f1	E2F transcription factor 1	16149	0.09
chr6_128504617_128505108	0.48	Pzp	PZP, alpha-2-macroglobulin like	9639	0.09
chr9_42253031_42253240	0.48	Sc5d	sterol-C5-desaturase	11065	0.17
chr18_20921400_20921643	0.46	Rnf125	ring finger protein 125	23104	0.17
chr5_134170212_134170373	0.45	Rcc1l	reculator of chromosome condensation 1 like	917	0.46
chr5_135741186_135741337	0.45	Tmem120a	transmembrane protein 120A	1138	0.32
chr15_56405270_56405431	0.45	Gm49213	predicted gene, 49213	9663	0.31
chr11_8607022_8607173	0.45	Tns3	tensin 3	17790	0.28
chr7_14430420_14431121	0.44	Sult2a8	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8	5677	0.17
chr7_19866622_19866883	0.44	Gm44659	predicted gene 44659	4686	0.08
chr9_77939601_77939775	0.43	Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	1603	0.32
chr13_10447671_10447864	0.43	Gm47407	predicted gene, 47407	69920	0.1
chr8_124156032_124156199	0.43	Gm3889	predicted gene 3889	3958	0.23
chr2_126549901_126550068	0.42	Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	2423	0.3
chr11_16704048_16704199	0.42	Gm25698	predicted gene, 25698	28588	0.15
chr5_65621209_65621360	0.41	Pds5a	PDS5 cohesin associated factor A	684	0.49
chr2_68873804_68874167	0.40	Cers6	ceramide synthase 6	12399	0.14
chr4_118129721_118129877	0.40	St3gal3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	5083	0.18
chr5_144905134_144905285	0.40	Smurf1	SMAD specific E3 ubiquitin protein ligase 1	7215	0.16
chr16_42880363_42880514	0.40	Zbtb20	zinc finger and BTB domain containing 20	4557	0.21
chr5_23894319_23894470	0.39	AC117663.1	solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), pseudogene	17951	0.11
chr5_150227882_150228033	0.39	Gm36378	predicted gene, 36378	15906	0.19
chr2_85050098_85050267	0.39	Tnks1bp1	tankyrase 1 binding protein 1	278	0.85
chr2_66712021_66712193	0.39	Scn7a	sodium channel, voltage-gated, type VII, alpha	72807	0.1
chr10_68465783_68466111	0.39	Cabcoco1	ciliary associated calcium binding coiled-coil 1	59820	0.13
chr12_109991265_109991416	0.38	Gm34667	predicted gene, 34667	32533	0.1
chr13_93630762_93631092	0.38	Gm15622	predicted gene 15622	5545	0.17
chr17_29056624_29056784	0.37	Gm41556	predicted gene, 41556	156	0.9
chr3_83014473_83014624	0.37	Gm30097	predicted gene, 30097	6060	0.15
chr16_29943850_29944001	0.37	Gm26569	predicted gene, 26569	2591	0.27
chr12_35501929_35502080	0.37	Ahr	aryl-hydrocarbon receptor	24775	0.16
chr3_104677278_104677438	0.37	Gm29560	predicted gene 29560	7348	0.1
chr11_50642967_50643387	0.36	Gm12198	predicted gene 12198	40729	0.12
chr12_62769518_62769809	0.36	Tspyl-ps	testis-specific protein, Y-encoded-like, pseudogene	65387	0.1
chr5_33934831_33935145	0.36	Nelfa	negative elongation factor complex member A, Whsc2	1262	0.31
chr5_76043835_76044206	0.36	Gm32780	predicted gene, 32780	922	0.54
chr4_11613136_11613395	0.34	Gm11832	predicted gene 11832	1742	0.3
chr17_50397611_50397796	0.34	Gm49906	predicted gene, 49906	58451	0.13
chr7_28832592_28832757	0.34	Lgals4	lectin, galactose binding, soluble 4	1180	0.23
chr19_58413245_58413576	0.34	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	41056	0.17
chr11_80430590_80430899	0.34	Psmd11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	857	0.6
chr14_116308331_116308711	0.34	Gm20713	predicted gene 20713	437243	0.01
chr17_93740961_93741187	0.34	Gm50003	predicted gene, 50003	60040	0.14
chr16_28841105_28841256	0.33	Mb21d2	Mab-21 domain containing 2	4813	0.32
chr1_151327603_151327859	0.33	Gm10138	predicted gene 10138	16351	0.14
chr12_21142640_21142894	0.33	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	30813	0.16
chr2_144078197_144078361	0.33	Banf2os	barrier to autointegration factor 2, opposite strand	9473	0.18
chr7_84106850_84107019	0.33	Cemip	cell migration inducing protein, hyaluronan binding	20432	0.16
chr9_110326292_110326443	0.33	Gm42638	predicted gene 42638	4197	0.13
chr1_59425292_59425875	0.33	Gm37737	predicted gene, 37737	23919	0.15
chr13_37667494_37667917	0.32	AI463229	expressed sequence AI463229	29	0.96
chr4_142077888_142078052	0.31	Tmem51os1	Tmem51 opposite strand 1	6002	0.15
chr16_91448666_91448817	0.31	Gm46562	predicted gene, 46562	9680	0.1
chr2_126729966_126730117	0.31	Gm10774	predicted pseudogene 10774	20484	0.13
chr19_46899287_46899584	0.31	Nt5c2	5'-nucleotidase, cytosolic II	10140	0.16
chr11_48771756_48771907	0.31	Gm12183	predicted gene 12183	18117	0.09
chr7_19928412_19928563	0.31	Pvr	poliovirus receptor	7327	0.08
chr1_186827890_186828061	0.30	A430105J06Rik	RIKEN cDNA A430105J06 gene	78579	0.07
chr6_147064387_147064568	0.30	Mrps35	mitochondrial ribosomal protein S35	3226	0.17
chr13_52972702_52972854	0.30	n-R5s54	nuclear encoded rRNA 5S 54	8046	0.18
chr15_31063560_31063731	0.30	4930430F21Rik	RIKEN cDNA 4930430F21 gene	24517	0.19
chr8_128463488_128463809	0.29	Nrp1	neuropilin 1	104251	0.07
chr1_139548791_139549059	0.29	Cfhr1	complement factor H-related 1	4674	0.22
chr17_73839522_73839982	0.29	Gm4948	predicted gene 4948	31598	0.14
chr10_61310200_61310351	0.29	Rpl27a-ps1	ribosomal protein L27A, pseudogene 1	445	0.76
chr10_28556799_28556950	0.28	Ptprk	protein tyrosine phosphatase, receptor type, K	3277	0.37
chr7_123193136_123193287	0.28	Tnrc6a	trinucleotide repeat containing 6a	13290	0.2
chr5_8899522_8899888	0.28	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	5756	0.16
chr16_17727505_17727656	0.28	Gm6048	predicted gene 6048	2204	0.14
chr14_75179701_75179900	0.28	Lcp1	lymphocyte cytosolic protein 1	3592	0.19
chr8_14825690_14825955	0.28	Dlgap2	DLG associated protein 2	48049	0.12
chr12_106479388_106479572	0.28	Gm3191	predicted gene 3191	20330	0.16
chr2_155539663_155540189	0.28	Mipep-ps	mitochondrial intermediate peptidase, pseudogene	2721	0.13
chr10_8089089_8089240	0.28	Gm48614	predicted gene, 48614	67872	0.11
chr16_14177645_14177827	0.28	Nde1	nudE neurodevelopment protein 1	2609	0.22
chr19_56602273_56602424	0.28	Nhlrc2	NHL repeat containing 2	31551	0.15
chr2_157550429_157550705	0.27	Gm14286	predicted gene 14286	5098	0.12
chr8_71405347_71405498	0.27	Ankle1	ankyrin repeat and LEM domain containing 1	588	0.54
chr19_20757249_20757433	0.27	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	29779	0.2
chr14_20319722_20320198	0.26	Nudt13	nudix (nucleoside diphosphate linked moiety X)-type motif 13	8531	0.12
chr19_25405865_25406016	0.26	Kank1	KN motif and ankyrin repeat domains 1	759	0.7
chr4_35013042_35013212	0.26	Gm12364	predicted gene 12364	50907	0.12
chr19_30128744_30128991	0.26	Gldc	glycine decarboxylase	16364	0.18
chr9_70270024_70270175	0.26	Myo1e	myosin IE	62731	0.11
chr7_75467233_75467387	0.26	Akap13	A kinase (PRKA) anchor protein 13	11442	0.16
chr4_19681355_19681795	0.25	Wwp1	WW domain containing E3 ubiquitin protein ligase 1	3127	0.29
chr4_99178772_99179088	0.25	Atg4c	autophagy related 4C, cysteine peptidase	15004	0.16
chr1_139660727_139661253	0.25	Cfhr3	complement factor H-related 3	91	0.97
chrX_12004590_12004741	0.25	Gm14512	predicted gene 14512	20197	0.22
chr2_33444795_33444946	0.25	Gm13536	predicted gene 13536	1932	0.27
chr10_61486909_61487060	0.25	Gm47595	predicted gene, 47595	9306	0.1
chr16_24394028_24394581	0.25	Lpp	LIM domain containing preferred translocation partner in lipoma	566	0.73
chr2_61401897_61402378	0.25	Gm22338	predicted gene, 22338	90629	0.09
chr18_20976494_20976645	0.25	Rnf125	ring finger protein 125	15097	0.19
chr3_21935040_21935222	0.24	Gm43674	predicted gene 43674	63337	0.12
chr1_93693606_93693762	0.24	Bok	BCL2-related ovarian killer	133	0.94
chr15_89210708_89210873	0.24	Ppp6r2	protein phosphatase 6, regulatory subunit 2	763	0.48
chr1_191254917_191255072	0.24	Gm37074	predicted gene, 37074	5570	0.14
chr7_113778913_113779066	0.24	Spon1	spondin 1, (f-spondin) extracellular matrix protein	12815	0.22
chr10_80621807_80621958	0.24	Csnk1g2	casein kinase 1, gamma 2	956	0.3
chr5_32195986_32196216	0.24	Gm9555	predicted gene 9555	10604	0.15
chr19_29268750_29269067	0.24	Jak2	Janus kinase 2	16467	0.17
chr13_64235436_64235605	0.24	Cdc14b	CDC14 cell division cycle 14B	13122	0.1
chr11_17501097_17501506	0.24	Gm12016	predicted gene 12016	137882	0.05
chr1_106177771_106177975	0.24	Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	6121	0.19
chr14_41170829_41171191	0.23	Sftpd	surfactant associated protein D	12125	0.11
chr2_103293475_103293769	0.23	Ehf	ets homologous factor	2685	0.27
chr12_86478264_86478415	0.23	Esrrb	estrogen related receptor, beta	8222	0.26
chr12_34268416_34268623	0.23	Gm18025	predicted gene, 18025	22616	0.27
chr9_36795863_36796248	0.23	Ei24	etoposide induced 2.4 mRNA	965	0.44
chr2_122781620_122782092	0.23	Sqor	sulfide quinone oxidoreductase	143	0.96
chr10_128272971_128273122	0.23	Stat2	signal transducer and activator of transcription 2	2470	0.11
chr3_83012044_83012325	0.23	Gm30097	predicted gene, 30097	3696	0.17
chr1_190204546_190204725	0.23	Prox1	prospero homeobox 1	33921	0.16
chr3_28736802_28736989	0.23	1700112D23Rik	RIKEN cDNA 1700112D23 gene	5345	0.16
chr12_101739231_101739640	0.22	Tc2n	tandem C2 domains, nuclear	20912	0.2
chr2_103625976_103626181	0.22	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	59768	0.1
chr16_37606843_37607024	0.22	Gm46559	predicted gene, 46559	10743	0.15
chr6_116910457_116910623	0.22	Gm43926	predicted gene, 43926	42979	0.16
chr13_114457557_114457872	0.22	Fst	follistatin	872	0.39
chr5_34296898_34297150	0.22	Cfap99	cilia and flagella associated protein 99	8424	0.11
chr2_165921904_165922055	0.22	Gm11461	predicted gene 11461	3862	0.16
chr1_78649448_78649613	0.22	Acsl3	acyl-CoA synthetase long-chain family member 3	8295	0.16
chr2_173047391_173047542	0.22	Gm14453	predicted gene 14453	12886	0.13
chr15_67469080_67469242	0.22	1700012I11Rik	RIKEN cDNA 1700012I11 gene	242392	0.02
chr2_114776001_114776450	0.21	Gm13975	predicted gene 13975	68113	0.11
chr12_8217539_8217881	0.21	Gm33037	predicted gene, 33037	8545	0.19
chr13_37512858_37513176	0.21	Gm29590	predicted gene 29590	3299	0.14
chr19_23024753_23025259	0.21	Gm50136	predicted gene, 50136	36448	0.17
chr10_83324249_83324444	0.21	Slc41a2	solute carrier family 41, member 2	1463	0.37
chr8_48545544_48545713	0.21	Tenm3	teneurin transmembrane protein 3	9685	0.29
chr9_69987908_69988201	0.21	Bnip2	BCL2/adenovirus E1B interacting protein 2	1412	0.32
chr4_132570302_132570458	0.21	Ptafr	platelet-activating factor receptor	6313	0.12
chr13_59771624_59772060	0.21	Etohd2	ethanol decreased 2	1876	0.15
chr12_85818362_85818513	0.21	Erg28	ergosterol biosynthesis 28	3813	0.2
chr10_20616725_20616876	0.21	Gm17230	predicted gene 17230	8835	0.25
chr13_28860566_28860730	0.21	2610307P16Rik	RIKEN cDNA 2610307P16 gene	22808	0.15
chr18_38431542_38431707	0.21	Ndfip1	Nedd4 family interacting protein 1	12640	0.15
chr6_128515921_128516189	0.21	Pzp	PZP, alpha-2-macroglobulin like	10648	0.09
chr19_33099137_33099698	0.20	Gm29946	predicted gene, 29946	23230	0.18
chr1_78650012_78650396	0.20	Acsl3	acyl-CoA synthetase long-chain family member 3	7621	0.17
chr2_60947339_60947519	0.20	Rbms1	RNA binding motif, single stranded interacting protein 1	15763	0.22
chr2_6718585_6718742	0.20	Celf2	CUGBP, Elav-like family member 2	2950	0.38
chr5_87135400_87135653	0.20	Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	4792	0.14
chr17_15341574_15341736	0.20	Gm7423	predicted gene 7423	19773	0.14
chr2_130578101_130578388	0.20	Oxt	oxytocin	2071	0.16
chr5_125405640_125405791	0.20	Dhx37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	10182	0.11
chr2_130961670_130961943	0.20	Atrn	attractin	20979	0.12
chr7_132931708_132932726	0.20	1500002F19Rik	RIKEN cDNA 1500002F19 gene	1020	0.34
chr2_165015545_165015729	0.20	Ncoa5	nuclear receptor coactivator 5	7576	0.14
chr5_18002991_18003251	0.20	Gnat3	guanine nucleotide binding protein, alpha transducing 3	40572	0.21
chr11_86963788_86963969	0.20	Ypel2	yippee like 2	8146	0.19
chr11_110011350_110011662	0.20	Abca8b	ATP-binding cassette, sub-family A (ABC1), member 8b	15661	0.2
chr8_86639656_86639807	0.20	Lonp2	lon peptidase 2, peroxisomal	8334	0.17
chr5_87335535_87335718	0.19	Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	1569	0.26
chr2_115592873_115593046	0.19	BC052040	cDNA sequence BC052040	11158	0.19
chr14_66080264_66080431	0.19	Adam2	a disintegrin and metallopeptidase domain 2	2614	0.24
chr5_140204413_140204753	0.19	Gm16120	predicted gene 16120	2802	0.25
chr19_41829163_41829397	0.19	Frat1	frequently rearranged in advanced T cell lymphomas	690	0.62
chr11_80146295_80146446	0.19	Tefm	transcription elongation factor, mitochondrial	4195	0.16
chr5_135776480_135776870	0.19	Styxl1	serine/threonine/tyrosine interacting-like 1	1563	0.22
chr10_44698108_44698268	0.19	Gm47388	predicted gene, 47388	1008	0.41
chr14_59548598_59548749	0.19	Cdadc1	cytidine and dCMP deaminase domain containing 1	49163	0.11
chr5_41572654_41572805	0.19	Rab28	RAB28, member RAS oncogene family	54773	0.16
chr13_51841406_51841559	0.19	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	5196	0.25
chr17_29381584_29381926	0.19	Fgd2	FYVE, RhoGEF and PH domain containing 2	5254	0.14
chr1_179836199_179836367	0.19	Ahctf1	AT hook containing transcription factor 1	32603	0.16
chr12_106479176_106479338	0.19	Gm3191	predicted gene 3191	20107	0.16
chr2_132654710_132655013	0.19	Rpl23a-ps4	ribosomal protein L23A, pseudogene 4	7381	0.12
chr5_8902050_8902207	0.19	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	8179	0.15
chr1_84877752_84878205	0.19	Fbxo36	F-box protein 36	8827	0.16
chr11_70746635_70746805	0.19	Gm12320	predicted gene 12320	8431	0.08
chr6_91514715_91514905	0.19	Xpc	xeroderma pigmentosum, complementation group C	985	0.32
chr19_33097519_33097677	0.19	Gm29946	predicted gene, 29946	25049	0.18
chr5_126565776_126566015	0.19	Gm24839	predicted gene, 24839	51914	0.14
chr9_55474509_55474664	0.19	Etfa	electron transferring flavoprotein, alpha polypeptide	12927	0.19
chr1_61649997_61650160	0.19	Gm37205	predicted gene, 37205	4345	0.17
chr4_134930449_134930699	0.19	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	324	0.86
chr6_51540654_51541195	0.19	Snx10	sorting nexin 10	3599	0.26
chr7_15086187_15086338	0.19	Gtpbp4-ps4	GTP binding protein 4, pseudogene 4	764	0.45
chr10_25563128_25563279	0.19	Gm29571	predicted gene 29571	26817	0.14
chr17_86458349_86458750	0.18	Prkce	protein kinase C, epsilon	32013	0.19
chr3_108640818_108640982	0.18	Clcc1	chloride channel CLIC-like 1	13013	0.11
chr2_103451907_103452157	0.18	Elf5	E74-like factor 5	3294	0.23
chr6_30563747_30563898	0.18	Cpa4	carboxypeptidase A4	4547	0.14
chr17_84269883_84270034	0.18	Gm24492	predicted gene, 24492	17789	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid3a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.1	0.2	GO:0060137	maternal process involved in parturition(GO:0060137)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.2	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.1	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.1	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.0	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0071503	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0050812	regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.0	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.0	0.0	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.0	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.0	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.0	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.0	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.7	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	0.0	GO:1900193	regulation of oocyte maturation(GO:1900193)
0.0	0.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0071649	regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.2	GO:0005638	lamin filament(GO:0005638)
0.1	GO:0032021	NELF complex(GO:0032021)
0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.2	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.2	GO:0030008	TRAPP complex(GO:0030008)
0.1	GO:0005915	zonula adherens(GO:0005915)
0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	GO:0097443	sorting endosome(GO:0097443)
0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.6	GO:0014704	intercalated disc(GO:0014704)
0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	GO:0000138	Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0031432	titin binding(GO:0031432)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism