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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Ascl2

Z-value: 0.53

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Transcription factors associated with Ascl2

Gene Symbol Gene ID Gene Info
Ascl2
ENSMUSG00000009248.5 achaete-scute family bHLH transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_142967530_142967799Ascl210530.436286-0.266.2e-01Click!

Activity of the Ascl2 motif across conditions

Conditions sorted by the z-value of the Ascl2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_67263308_67263719 0.38 Mlf1
 myeloid leukemia factor 1
 110584
 0.06
chr16_17208938_17209184 0.25 Rimbp3
 RIMS binding protein 3
 458
 0.65
chr2_173158061_173158212 0.23 Pck1
 phosphoenolpyruvate carboxykinase 1, cytosolic
 5054
 0.19
chr10_63410268_63410432 0.22 Gm7530
 predicted gene 7530
 2649
 0.19
chr14_19751408_19751584 0.22 Nid2
 nidogen 2
 212
 0.93
chr12_100199636_100199926 0.20 Calm1
 calmodulin 1
 252
 0.89
chr9_65296934_65297096 0.19 Gm16218
 predicted gene 16218
 904
 0.39
chr1_160692286_160692437 0.18 Gm37328
 predicted gene, 37328
 34320
 0.09
chr15_31058451_31058629 0.17 4930430F21Rik
 RIKEN cDNA 4930430F21 gene
 19412
 0.2
chr2_173159829_173160580 0.16 Pck1
 phosphoenolpyruvate carboxykinase 1, cytosolic
 7122
 0.18
chr2_25262755_25263227 0.16 Tprn
 taperin
 373
 0.59
chr11_102399997_102400189 0.15 Rundc3a
 RUN domain containing 3A
 235
 0.85
chr1_184873376_184873577 0.15 C130074G19Rik
 RIKEN cDNA C130074G19 gene
 9742
 0.16
chr8_94173317_94173477 0.15 Gm45774
 predicted gene 45774
 15
 0.89
chr8_10937238_10937412 0.14 Gm45042
 predicted gene 45042
 7438
 0.11
chr10_69208384_69208535 0.14 Rhobtb1
 Rho-related BTB domain containing 1
 93
 0.97
chr2_31519156_31519420 0.14 Ass1
 argininosuccinate synthetase 1
 798
 0.61
chr5_114561036_114561196 0.14 Fam222a
 family with sequence similarity 222, member A
 6900
 0.17
chr5_124225128_124225319 0.14 Pitpnm2os1
 phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1
 4502
 0.13
chr14_65740190_65740357 0.13 Scara5
 scavenger receptor class A, member 5
 63796
 0.1
chr12_28910370_28910535 0.13 Gm31508
 predicted gene, 31508
 223
 0.94
chr1_93137985_93138369 0.13 Agxt
 alanine-glyoxylate aminotransferase
 1702
 0.26
chr11_120013435_120013644 0.13 Aatk
 apoptosis-associated tyrosine kinase
 1131
 0.23
chr5_24976790_24976954 0.13 1500035N22Rik
 RIKEN cDNA 1500035N22 gene
 8970
 0.18
chr19_46141233_46141384 0.13 Pitx3
 paired-like homeodomain transcription factor 3
 325
 0.82
chr1_59157472_59157626 0.13 Mpp4
 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
 1112
 0.34
chr7_114325255_114325465 0.12 Psma1
 proteasome subunit alpha 1
 49242
 0.13
chr3_116329378_116329892 0.12 Gm29151
 predicted gene 29151
 20468
 0.17
chr1_36149451_36149602 0.12 Uggt1
 UDP-glucose glycoprotein glucosyltransferase 1
 998
 0.45
chr12_84187018_84187182 0.12 Gm19327
 predicted gene, 19327
 706
 0.52
chr12_28800275_28800436 0.12 Gm48905
 predicted gene, 48905
 9783
 0.16
chr19_3893794_3894051 0.12 Chka
 choline kinase alpha
 2191
 0.13
chr9_47324524_47324675 0.12 Gm31816
 predicted gene, 31816
 38151
 0.19
chr4_117040674_117041081 0.12 Eif2b3
 eukaryotic translation initiation factor 2B, subunit 3
 3599
 0.12
chr3_108788010_108788161 0.12 Stxbp3
 syntaxin binding protein 3
 9699
 0.15
chr19_32648548_32648744 0.12 Papss2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
 28641
 0.18
chr2_25472167_25472318 0.12 Ptgds
 prostaglandin D2 synthase (brain)
 2196
 0.12
chr4_82415983_82416134 0.11 n-R5s188
 nuclear encoded rRNA 5S 188
 23352
 0.23
chr19_45749067_45749428 0.11 Gm15491
 predicted gene 15491
 261
 0.52
chr10_75783826_75784124 0.11 Gstt3
 glutathione S-transferase, theta 3
 2561
 0.13
chr13_74209069_74209298 0.11 Exoc3
 exocyst complex component 3
 451
 0.81
chr19_46628011_46628401 0.11 Wbp1l
 WW domain binding protein 1 like
 4805
 0.15
chrX_63961215_63961366 0.11 Gm8260
 predicted gene 8260
 86616
 0.1
chr7_30051105_30051256 0.11 Zfp14
 zinc finger protein 14
 193
 0.88
chr13_93628549_93628834 0.11 Gm15622
 predicted gene 15622
 3309
 0.2
chr17_31306868_31307019 0.11 Slc37a1
 solute carrier family 37 (glycerol-3-phosphate transporter), member 1
 522
 0.71
chr17_56108904_56109250 0.11 Plin4
 perilipin 4
 725
 0.45
chr2_27212850_27213071 0.11 Sardh
 sarcosine dehydrogenase
 2672
 0.2
chrX_169904110_169904261 0.11 Mid1
 midline 1
 22766
 0.2
chr11_35458160_35458335 0.11 Slit3
 slit guidance ligand 3
 86438
 0.09
chr6_149138694_149138910 0.11 Etfbkmt
 electron transfer flavoprotein beta subunit lysine methyltransferase
 1047
 0.41
chr14_12103232_12103447 0.11 Ptprg
 protein tyrosine phosphatase, receptor type, G
 12179
 0.23
chr17_49440803_49440954 0.11 Mocs1
 molybdenum cofactor synthesis 1
 7682
 0.22
chr12_112597485_112597658 0.11 Inf2
 inverted formin, FH2 and WH2 domain containing
 7086
 0.14
chr4_141663419_141663714 0.11 Plekhm2
 pleckstrin homology domain containing, family M (with RUN domain) member 2
 552
 0.67
chr6_72120521_72121047 0.11 4933431G14Rik
 RIKEN cDNA 4933431G14 gene
 2156
 0.2
chr10_24915615_24916009 0.10 Arg1
 arginase, liver
 595
 0.65
chr7_112276934_112277125 0.10 Mical2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 5730
 0.31
chr5_122060223_122060392 0.10 Cux2
 cut-like homeobox 2
 10205
 0.14
chr8_104909005_104909158 0.10 Gm8798
 predicted gene 8798
 16335
 0.09
chr10_80444503_80444654 0.10 Tcf3
 transcription factor 3
 10931
 0.09
chr9_107738378_107738568 0.10 Rbm5
 RNA binding motif protein 5
 5761
 0.11
chr9_52056529_52056697 0.10 Rdx
 radixin
 8342
 0.19
chr8_104443177_104443346 0.10 Dync1li2
 dynein, cytoplasmic 1 light intermediate chain 2
 214
 0.83
chr2_31513768_31514291 0.10 Ass1
 argininosuccinate synthetase 1
 4461
 0.2
chr6_145606729_145606899 0.10 Lmntd1
 lamin tail domain containing 1
 7155
 0.21
chr17_25068673_25068863 0.10 Tmem204
 transmembrane protein 204
 9456
 0.11
chr2_180788221_180788717 0.10 Bhlhe23
 basic helix-loop-helix family, member e23
 11569
 0.11
chrX_108664177_108664328 0.10 Gm379
 predicted gene 379
 203
 0.97
chr8_68277116_68277418 0.10 Sh2d4a
 SH2 domain containing 4A
 700
 0.69
chr17_34733622_34734232 0.10 C4b
 complement component 4B (Chido blood group)
 2172
 0.12
chr2_31491761_31492352 0.10 Ass1
 argininosuccinate synthetase 1
 5716
 0.2
chr2_167148083_167148259 0.10 1110018N20Rik
 RIKEN cDNA 1110018N20 gene
 40531
 0.08
chr8_93270889_93271065 0.10 Ces1f
 carboxylesterase 1F
 3572
 0.18
chr5_121761085_121761315 0.10 Atxn2
 ataxin 2
 12004
 0.12
chr7_30943687_30943953 0.10 Hamp
 hepcidin antimicrobial peptide
 212
 0.82
chr11_69122450_69122661 0.10 9130213A22Rik
 RIKEN cDNA 9130213A22 gene
 34
 0.93
chr8_124273757_124274124 0.10 Galnt2
 polypeptide N-acetylgalactosaminyltransferase 2
 21163
 0.15
chr14_120534643_120535027 0.10 Rap2a
 RAS related protein 2a
 56391
 0.14
chr5_8988023_8988336 0.10 Crot
 carnitine O-octanoyltransferase
 6035
 0.13
chr15_75996647_75996807 0.10 Mapk15
 mitogen-activated protein kinase 15
 14
 0.94
chr14_8251423_8251762 0.10 Acox2
 acyl-Coenzyme A oxidase 2, branched chain
 1930
 0.34
chr2_167877367_167877523 0.10 Gm14319
 predicted gene 14319
 18860
 0.16
chr16_11034212_11034466 0.10 Gm10832
 predicted gene 10832
 2383
 0.16
chr17_28279922_28280073 0.09 Ppard
 peroxisome proliferator activator receptor delta
 7878
 0.11
chr7_28732426_28732636 0.09 Fbxo17
 F-box protein 17
 31
 0.95
chr6_117178128_117178348 0.09 Cxcl12
 chemokine (C-X-C motif) ligand 12
 9661
 0.18
chr9_77964186_77964368 0.09 Elovl5
 ELOVL family member 5, elongation of long chain fatty acids (yeast)
 22986
 0.11
chr6_29539642_29539820 0.09 Irf5
 interferon regulatory factor 5
 1415
 0.29
chr1_190164468_190164683 0.09 Gm28172
 predicted gene 28172
 4095
 0.21
chr13_96661137_96661370 0.09 Hmgcr
 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
 4586
 0.17
chr11_109616366_109616667 0.09 Gm11685
 predicted gene 11685
 196
 0.93
chr8_126498607_126498804 0.09 Gm6091
 predicted pseudogene 6091
 22293
 0.18
chr2_180756949_180757112 0.09 Gm14343
 predicted gene 14343
 18373
 0.1
chr2_48411517_48411668 0.09 Gm13472
 predicted gene 13472
 23555
 0.19
chr16_23974024_23974210 0.09 Bcl6
 B cell leukemia/lymphoma 6
 1737
 0.33
chr13_37761078_37761249 0.09 Gm31600
 predicted gene, 31600
 585
 0.68
chr12_108292499_108292690 0.09 Hhipl1
 hedgehog interacting protein-like 1
 13676
 0.15
chr16_67621078_67621243 0.09 Cadm2
 cell adhesion molecule 2
 252
 0.95
chr11_119969786_119969965 0.09 Baiap2
 brain-specific angiogenesis inhibitor 1-associated protein 2
 9854
 0.11
chr11_7136281_7136476 0.09 Adcy1
 adenylate cyclase 1
 23504
 0.18
chr2_173161537_173161720 0.09 Pck1
 phosphoenolpyruvate carboxykinase 1, cytosolic
 8546
 0.17
chr11_120012134_120012364 0.09 Aatk
 apoptosis-associated tyrosine kinase
 159
 0.9
chr5_8962841_8962998 0.09 Abcb4
 ATP-binding cassette, sub-family B (MDR/TAP), member 4
 4367
 0.15
chr6_22037034_22037204 0.09 Cped1
 cadherin-like and PC-esterase domain containing 1
 11176
 0.27
chr11_97449921_97450124 0.09 Arhgap23
 Rho GTPase activating protein 23
 138
 0.95
chr1_39070328_39070509 0.09 Gm37821
 predicted gene, 37821
 12781
 0.17
chr4_44994891_44995176 0.09 Grhpr
 glyoxylate reductase/hydroxypyruvate reductase
 13533
 0.1
chr9_67842866_67843237 0.09 Vps13c
 vacuolar protein sorting 13C
 2639
 0.27
chr18_46651026_46651177 0.09 Gm3734
 predicted gene 3734
 20294
 0.14
chr19_56652542_56652727 0.09 Gm32441
 predicted gene, 32441
 11977
 0.17
chr1_67195779_67195930 0.09 Gm15668
 predicted gene 15668
 53346
 0.13
chr3_152478706_152478877 0.09 Ak5
 adenylate kinase 5
 276
 0.91
chr19_3451534_3452133 0.09 Ppp6r3
 protein phosphatase 6, regulatory subunit 3
 19172
 0.12
chr4_137795816_137796289 0.09 Alpl
 alkaline phosphatase, liver/bone/kidney
 178
 0.96
chr7_141335382_141335533 0.09 Tmem80
 transmembrane protein 80
 1799
 0.16
chr4_63494908_63495098 0.09 Whrn
 whirlin
 244
 0.91
chr19_37509643_37509826 0.09 Exoc6
 exocyst complex component 6
 11145
 0.17
chr9_83834067_83834712 0.09 Ttk
 Ttk protein kinase
 300
 0.91
chr8_90834012_90834186 0.09 Chd9
 chromodomain helicase DNA binding protein 9
 5243
 0.14
chr9_110985950_110986443 0.09 1700061E17Rik
 RIKEN cDNA 1700061E17 gene
 5
 0.94
chr6_72360494_72360859 0.09 Rnf181
 ring finger protein 181
 391
 0.72
chr2_26593869_26594069 0.09 Egfl7
 EGF-like domain 7
 1822
 0.16
chr2_103472788_103473367 0.09 Cat
 catalase
 12048
 0.18
chr15_79002341_79002492 0.09 Mir6956
 microRNA 6956
 193
 0.52
chr19_42602482_42602861 0.09 Loxl4
 lysyl oxidase-like 4
 650
 0.71
chr11_117964790_117965236 0.09 Socs3
 suppressor of cytokine signaling 3
 4173
 0.16
chr10_122454632_122454783 0.09 Gm48878
 predicted gene, 48878
 575
 0.76
chr5_140389137_140389453 0.09 Snx8
 sorting nexin 8
 33
 0.97
chr2_32414031_32414217 0.09 Slc25a25
 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
 2447
 0.14
chr8_106606041_106606388 0.09 Cdh1
 cadherin 1
 2071
 0.29
chr5_120483296_120483855 0.09 Gm15690
 predicted gene 15690
 2672
 0.15
chr3_75950402_75950574 0.09 Gm37685
 predicted gene, 37685
 1636
 0.35
chr12_112675159_112675325 0.09 Akt1
 thymoma viral proto-oncogene 1
 358
 0.75
chr3_86002499_86002650 0.09 Prss48
 protease, serine 48
 83
 0.96
chr8_123653291_123653442 0.09 Rhou
 ras homolog family member U
 563
 0.38
chr2_93477672_93477838 0.09 Gm10804
 predicted gene 10804
 9316
 0.19
chr5_87080846_87081015 0.09 Ugt2b36
 UDP glucuronosyltransferase 2 family, polypeptide B36
 10227
 0.11
chr2_122775480_122775660 0.08 Sqor
 sulfide quinone oxidoreductase
 3852
 0.22
chr11_102214881_102215057 0.08 Hdac5
 histone deacetylase 5
 3959
 0.11
chr8_46512530_46512928 0.08 Acsl1
 acyl-CoA synthetase long-chain family member 1
 14057
 0.15
chr14_34675574_34675754 0.08 Wapl
 WAPL cohesin release factor
 1491
 0.26
chr6_72233008_72233332 0.08 Atoh8
 atonal bHLH transcription factor 8
 1367
 0.39
chr3_69403326_69403495 0.08 Gm17213
 predicted gene 17213
 28958
 0.17
chr11_85846806_85847022 0.08 Gm11444
 predicted gene 11444
 3419
 0.17
chr3_84639824_84639982 0.08 Tmem154
 transmembrane protein 154
 26289
 0.17
chr11_78157696_78157847 0.08 Traf4
 TNF receptor associated factor 4
 7745
 0.07
chr13_96749686_96749877 0.08 Ankrd31
 ankyrin repeat domain 31
 1249
 0.45
chr17_56207962_56208313 0.08 Dpp9
 dipeptidylpeptidase 9
 1071
 0.32
chr3_67262698_67262957 0.08 Mlf1
 myeloid leukemia factor 1
 111270
 0.06
chr5_33901574_33901762 0.08 Mir7024
 microRNA 7024
 2697
 0.18
chr12_84221379_84221549 0.08 Elmsan1
 ELM2 and Myb/SANT-like domain containing 1
 2583
 0.16
chr7_121907300_121907714 0.08 Scnn1b
 sodium channel, nonvoltage-gated 1 beta
 8279
 0.18
chr16_18069271_18069422 0.08 Dgcr6
 DiGeorge syndrome critical region gene 6
 134
 0.94
chr13_7414710_7414870 0.08 Gm36074
 predicted gene, 36074
 31719
 0.23
chr5_93250297_93250457 0.08 Ccng2
 cyclin G2
 16880
 0.14
chr5_115575131_115575282 0.08 Mir7029
 microRNA 7029
 5743
 0.11
chr2_163551700_163552131 0.08 Hnf4a
 hepatic nuclear factor 4, alpha
 1832
 0.25
chr5_123977607_123977811 0.08 Hip1r
 huntingtin interacting protein 1 related
 2545
 0.16
chr8_14257136_14257302 0.08 Gm26184
 predicted gene, 26184
 16092
 0.22
chr1_134955632_134955799 0.08 Ppp1r12b
 protein phosphatase 1, regulatory subunit 12B
 136
 0.96
chr1_36512638_36512794 0.08 Cnnm3
 cyclin M3
 381
 0.72
chr2_32678870_32679034 0.08 Gm26236
 predicted gene, 26236
 3843
 0.08
chr5_114606575_114606726 0.08 Trpv4
 transient receptor potential cation channel, subfamily V, member 4
 23988
 0.13
chr2_110007906_110008057 0.08 Lgr4
 leucine-rich repeat-containing G protein-coupled receptor 4
 7453
 0.19
chr18_46718177_46718358 0.08 Cdo1
 cysteine dioxygenase 1, cytosolic
 9762
 0.13
chr15_4727530_4727980 0.08 C6
 complement component 6
 539
 0.84
chr8_40187640_40187799 0.08 Fgf20
 fibroblast growth factor 20
 99234
 0.07
chr8_121573324_121573508 0.08 Fbxo31
 F-box protein 31
 5331
 0.12
chr19_45036974_45037129 0.08 Pdzd7
 PDZ domain containing 7
 7036
 0.1
chr11_101070404_101070591 0.08 Naglu
 alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
 485
 0.62
chr18_4970911_4971104 0.08 Svil
 supervillin
 22806
 0.26
chr1_74047431_74047619 0.08 Tns1
 tensin 1
 10368
 0.21
chr3_129970893_129971067 0.08 Mcub
 mitochondrial calcium uniporter dominant negative beta subunit
 774
 0.62
chr11_115608626_115608777 0.08 Mif4gd
 MIF4G domain containing
 3425
 0.11
chr17_12418655_12418810 0.08 Plg
 plasminogen
 40073
 0.12
chr15_102006414_102006639 0.08 Krt8
 keratin 8
 2044
 0.19
chr6_133105397_133105578 0.08 Smim10l1
 small integral membrane protein 10 like 1
 5
 0.95
chr10_19525625_19525776 0.08 Gm48563
 predicted gene, 48563
 3050
 0.27
chr8_70182055_70182225 0.08 Tmem161a
 transmembrane protein 161A
 1601
 0.22
chr3_84647383_84647687 0.08 Tmem154
 transmembrane protein 154
 18657
 0.2
chr2_32727754_32727916 0.08 Sh2d3c
 SH2 domain containing 3C
 129
 0.89
chr15_67116763_67117052 0.08 St3gal1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2915
 0.34
chr14_30922623_30922783 0.08 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 846
 0.45
chr10_94055869_94056059 0.08 Fgd6
 FYVE, RhoGEF and PH domain containing 6
 16578
 0.11
chr1_182609269_182609652 0.08 Capn8
 calpain 8
 44422
 0.12
chr7_78782525_78782681 0.08 Mrpl46
 mitochondrial ribosomal protein L46
 486
 0.44
chr8_111745534_111745719 0.08 Bcar1
 breast cancer anti-estrogen resistance 1
 1817
 0.34
chr6_72117206_72117587 0.08 St3gal5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 2164
 0.2
chr2_158768137_158768288 0.07 Fam83d
 family with sequence similarity 83, member D
 119
 0.96
chr15_75981322_75981497 0.07 Ccdc166
 coiled-coil domain containing 166
 1033
 0.28
chr13_37778325_37778511 0.07 Rreb1
 ras responsive element binding protein 1
 18
 0.97
chr18_75818786_75819091 0.07 Zbtb7c
 zinc finger and BTB domain containing 7C
 1240
 0.52
chr9_113127551_113127725 0.07 Gm36251
 predicted gene, 36251
 4609
 0.31
chr12_8000122_8000489 0.07 Apob
 apolipoprotein B
 12054
 0.22
chr17_31908788_31908992 0.07 2310015A16Rik
 RIKEN cDNA 2310015A16 gene
 139
 0.94
chr10_94514734_94514917 0.07 Tmcc3
 transmembrane and coiled coil domains 3
 32
 0.98
chr1_164210089_164210240 0.07 Slc19a2
 solute carrier family 19 (thiamine transporter), member 2
 38882
 0.1
chr4_48125260_48125479 0.07 Stx17
 syntaxin 17
 434
 0.87
chrX_74023375_74023542 0.07 Irak1
 interleukin-1 receptor-associated kinase 1
 50
 0.58

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0010963 regulation of L-arginine import(GO:0010963)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:2000392 regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0006563 L-serine metabolic process(GO:0006563)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.0 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.0 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0060066 oviduct development(GO:0060066)
0.0 0.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.0 0.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.1 GO:0097466 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.0 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:1902988 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.0 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.0 GO:1901656 glycoside transport(GO:1901656)
0.0 0.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.0 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.0 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.0 GO:1990696 USH2 complex(GO:1990696)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.0 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol