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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Barhl2

Z-value: 1.88

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Transcription factors associated with Barhl2

Gene Symbol	Gene ID	Gene Info
Barhl2 Ensembl NCBI MGI UniProt	ENSMUSG00000034384.10	Barhl2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Barhl2	chr5_106462010_106462184	3931	0.202322	0.97	1.1e-03	Click!
Barhl2	chr5_106416670_106416832	41415	0.100209	-0.90	1.4e-02	Click!

Activity of the Barhl2 motif across conditions

Conditions sorted by the z-value of the Barhl2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_51255928_51256079	1.32	Elf2	E74-like factor 2	4238	0.15
chr2_177467353_177467504	1.19	Zfp970	zinc finger protein 970	2582	0.22
chr7_99985802_99985987	1.09	Rnf169	ring finger protein 169	5446	0.14
chr6_72155996_72156358	1.02	Gm38832	predicted gene, 38832	6672	0.15
chr15_36578902_36579081	0.92	Gm44310	predicted gene, 44310	4553	0.16
chr5_66421556_66421781	0.91	Gm43792	predicted gene 43792	10458	0.16
chr13_37756552_37756712	0.89	Gm31600	predicted gene, 31600	5116	0.16
chr7_24928137_24928288	0.88	Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	4849	0.1
chr12_24706013_24706174	0.79	Rrm2	ribonucleotide reductase M2	2148	0.23
chr4_49340688_49340844	0.77	Gm12453	predicted gene 12453	1482	0.35
chr12_16536781_16536932	0.77	Lpin1	lipin 1	25182	0.22
chr12_30922518_30922679	0.73	Sh3yl1	Sh3 domain YSC-like 1	10411	0.17
chr7_99119169_99119320	0.73	Gm44975	predicted gene 44975	4215	0.16
chr18_75039451_75039635	0.73	Dym	dymeclin	7781	0.11
chr11_4101980_4102159	0.72	Gm11955	predicted gene 11955	5686	0.09
chr2_126872795_126872950	0.72	Trpm7	transient receptor potential cation channel, subfamily M, member 7	3245	0.2
chr1_151144420_151144571	0.72	C730036E19Rik	RIKEN cDNA C730036E19 gene	6461	0.13
chr2_163301297_163301733	0.71	Tox2	TOX high mobility group box family member 2	18863	0.19
chr14_63171725_63171990	0.69	Fdft1	farnesyl diphosphate farnesyl transferase 1	5936	0.15
chr9_74959539_74959918	0.68	Fam214a	family with sequence similarity 214, member A	6656	0.21
chr1_74245666_74245817	0.67	Arpc2	actin related protein 2/3 complex, subunit 2	9191	0.09
chr8_93195399_93195725	0.67	Ces1d	carboxylesterase 1D	2215	0.21
chr8_35217053_35217251	0.66	Gm34474	predicted gene, 34474	1486	0.33
chr8_24398458_24398628	0.65	Gm30692	predicted gene, 30692	13636	0.15
chr10_111203502_111203653	0.64	Gm17849	predicted gene, 17849	23625	0.14
chr15_84987122_84987708	0.64	5031439G07Rik	RIKEN cDNA 5031439G07 gene	556	0.65
chr2_18048052_18048234	0.63	Skida1	SKI/DACH domain containing 1	306	0.82
chr9_47348407_47348558	0.63	Gm31816	predicted gene, 31816	14268	0.26
chr12_30200282_30200708	0.63	Sntg2	syntrophin, gamma 2	840	0.72
chr4_71609659_71609810	0.62	Gm11231	predicted gene 11231	68279	0.13
chr7_141518007_141518371	0.61	Gm45416	predicted gene 45416	414	0.69
chr6_72117206_72117587	0.61	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	2164	0.2
chr6_29847724_29848011	0.60	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	5893	0.2
chr16_24059680_24059889	0.60	Gm49518	predicted gene, 49518	19878	0.15
chr16_78574210_78574428	0.60	D16Ertd472e	DNA segment, Chr 16, ERATO Doi 472, expressed	2315	0.29
chr11_79753440_79753625	0.60	Mir365-2	microRNA 365-2	27132	0.12
chr8_114129813_114130087	0.59	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	3607	0.35
chr17_35837067_35837599	0.58	Tubb5	tubulin, beta 5 class I	273	0.75
chr6_24610042_24610446	0.58	Lmod2	leiomodin 2 (cardiac)	12482	0.14
chr6_50587768_50588064	0.58	4921507P07Rik	RIKEN cDNA 4921507P07 gene	8716	0.09
chr2_103808262_103808413	0.58	4930547E08Rik	RIKEN cDNA 4930547E08 gene	2285	0.15
chr1_133527477_133527628	0.58	Gm8596	predicted gene 8596	1927	0.35
chr9_30820894_30821215	0.57	Gm31013	predicted gene, 31013	39575	0.16
chr13_115653702_115653853	0.57	Gm47892	predicted gene, 47892	65722	0.13
chr7_119965208_119965675	0.57	Dnah3	dynein, axonemal, heavy chain 3	2401	0.24
chr12_81173777_81173928	0.56	Mir3067	microRNA 3067	7701	0.23
chr10_89722029_89722190	0.56	Actr6	ARP6 actin-related protein 6	9949	0.17
chr16_58629623_58629774	0.56	Ftdc2	ferritin domain containing 2	9041	0.14
chr8_91376537_91376735	0.56	Fto	fat mass and obesity associated	13919	0.15
chr12_33343907_33344327	0.55	Atxn7l1	ataxin 7-like 1	1188	0.48
chr4_122961124_122961316	0.55	Mfsd2a	major facilitator superfamily domain containing 2A	32	0.55
chr11_55022576_55022727	0.55	Anxa6	annexin A6	10764	0.16
chr19_4596445_4596623	0.55	Pcx	pyruvate carboxylase	2126	0.2
chr10_43487752_43488061	0.54	Bend3	BEN domain containing 3	2672	0.19
chr14_7827742_7828144	0.54	Flnb	filamin, beta	9986	0.16
chr2_30174548_30174718	0.53	Spout1	SPOUT domain containing methyltransferase 1	2872	0.13
chr18_33386505_33386656	0.53	Gm5503	predicted gene 5503	1625	0.48
chr19_40223143_40223322	0.53	Pdlim1	PDZ and LIM domain 1 (elfin)	124	0.95
chr2_6083786_6083961	0.52	Upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	33446	0.13
chr19_46089989_46090140	0.51	Nolc1	nucleolar and coiled-body phosphoprotein 1	14010	0.11
chr9_65289767_65289960	0.51	Clpx	caseinolytic mitochondrial matrix peptidase chaperone subunit	4397	0.12
chr7_67696401_67696754	0.51	Gm44669	predicted gene 44669	15274	0.13
chr3_129505079_129505267	0.51	Gm35986	predicted gene, 35986	26936	0.13
chr9_79790411_79790586	0.51	Tmem30a	transmembrane protein 30A	2932	0.19
chr18_39237141_39237343	0.51	Arhgap26	Rho GTPase activating protein 26	9874	0.26
chr4_101341143_101341295	0.51	Gm12793	predicted gene 12793	138	0.92
chr2_165019440_165019637	0.50	Ncoa5	nuclear receptor coactivator 5	3675	0.17
chr17_83178597_83178785	0.50	Pkdcc	protein kinase domain containing, cytoplasmic	36601	0.16
chr9_63555594_63556179	0.50	Gm16759	predicted gene, 16759	24534	0.17
chr14_21143338_21143517	0.50	Adk	adenosine kinase	67275	0.11
chr2_64094972_64095229	0.50	Fign	fidgetin	2888	0.42
chr7_140707331_140707529	0.50	Olfr541	olfactory receptor 541	3265	0.12
chr14_75851007_75851170	0.49	Snora31	small nucleolar RNA, H/ACA box 31	3183	0.17
chr10_71375716_71375880	0.49	Ipmk	inositol polyphosphate multikinase	5951	0.17
chr11_120677666_120677817	0.49	Aspscr1	alveolar soft part sarcoma chromosome region, candidate 1 (human)	402	0.61
chr8_93183570_93183871	0.49	Gm45909	predicted gene 45909	7638	0.14
chr1_151341714_151342067	0.48	Gm10138	predicted gene 10138	2192	0.22
chr11_79792604_79792780	0.48	9130204K15Rik	RIKEN cDNA 9130204K15 gene	9805	0.18
chr15_85673568_85673951	0.48	Lncppara	long noncoding RNA near Ppara	20143	0.13
chr13_19394098_19394409	0.48	Gm42683	predicted gene 42683	1200	0.38
chr11_101707734_101707885	0.48	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	25110	0.1
chr10_67100073_67100416	0.48	Reep3	receptor accessory protein 3	3299	0.24
chr8_45731419_45731570	0.48	Sorbs2	sorbin and SH3 domain containing 2	11687	0.2
chr3_15201102_15201265	0.48	Gm33819	predicted gene, 33819	29741	0.23
chr14_21177906_21178057	0.48	Adk	adenosine kinase	101829	0.07
chr11_101452213_101452392	0.47	Ifi35	interferon-induced protein 35	3732	0.08
chr3_34080161_34080466	0.47	Dnajc19	DnaJ heat shock protein family (Hsp40) member C19	133	0.94
chr2_48404312_48404494	0.47	Gm13472	predicted gene 13472	16366	0.2
chr13_47693489_47693893	0.47	4930471G24Rik	RIKEN cDNA 4930471G24 gene	26141	0.25
chr17_80775981_80776132	0.47	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	47571	0.14
chr12_80181689_80181850	0.47	Actn1	actinin, alpha 1	3079	0.19
chr5_24824691_24824842	0.46	Rheb	Ras homolog enriched in brain	10807	0.16
chr15_9334693_9335268	0.46	Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	570	0.78
chr3_158035265_158035416	0.46	Gm43362	predicted gene 43362	1069	0.28
chr15_22791062_22791223	0.46	Hnrnpa1l2-ps2	heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene 2	76312	0.12
chr13_96981889_96982402	0.46	Gm48597	predicted gene, 48597	31231	0.12
chr1_8843106_8843274	0.46	Gm6152	predicted gene 6152	13077	0.14
chr13_48966249_48966400	0.46	Fam120a	family with sequence similarity 120, member A	1693	0.44
chr14_31604102_31604253	0.46	Hacl1	2-hydroxyacyl-CoA lyase 1	6157	0.16
chr7_113214865_113215031	0.46	Arntl	aryl hydrocarbon receptor nuclear translocator-like	7391	0.23
chr3_149180418_149180610	0.45	Gm42647	predicted gene 42647	29757	0.19
chr17_35590917_35591091	0.45	Sfta2	surfactant associated 2	10545	0.08
chr2_170511584_170512109	0.45	Gm16796	predicted gene, 16796	81	0.76
chr17_28693502_28693661	0.45	Mapk14	mitogen-activated protein kinase 14	1013	0.41
chr3_18210346_18210497	0.45	Gm23686	predicted gene, 23686	32796	0.17
chr8_35206583_35206734	0.44	Gm34474	predicted gene, 34474	11980	0.14
chr13_95609612_95609763	0.44	F2r	coagulation factor II (thrombin) receptor	8800	0.16
chr13_115653330_115653690	0.44	Gm47892	predicted gene, 47892	65989	0.13
chr1_191720413_191720955	0.44	Lpgat1	lysophosphatidylglycerol acyltransferase 1	2163	0.28
chr13_75730593_75731025	0.44	Gm48302	predicted gene, 48302	3530	0.17
chr7_59244646_59244797	0.44	Ube3a	ubiquitin protein ligase E3A	1813	0.12
chr14_13957752_13957916	0.44	Thoc7	THO complex 7	203	0.93
chr2_27212850_27213071	0.44	Sardh	sarcosine dehydrogenase	2672	0.2
chr1_192712059_192712228	0.43	Hhat	hedgehog acyltransferase	14065	0.2
chr8_90930923_90931074	0.43	Chd9	chromodomain helicase DNA binding protein 9	1346	0.38
chr8_105129563_105129714	0.43	Ces4a	carboxylesterase 4A	2162	0.17
chr3_122860199_122860420	0.43	Gm9364	predicted gene 9364	1604	0.31
chr3_57448360_57448527	0.42	Tm4sf4	transmembrane 4 superfamily member 4	23129	0.19
chr6_99301780_99301979	0.42	Foxp1	forkhead box P1	35347	0.2
chr5_123978551_123978730	0.41	Hip1r	huntingtin interacting protein 1 related	1614	0.23
chr8_122697244_122697412	0.41	Gm10612	predicted gene 10612	532	0.59
chr18_46714296_46714492	0.41	Cdo1	cysteine dioxygenase 1, cytosolic	13635	0.13
chr3_52473197_52473354	0.41	Gm30173	predicted gene, 30173	43689	0.14
chr4_44192916_44193352	0.41	Rnf38	ring finger protein 38	24795	0.15
chr13_16761081_16761364	0.41	Gm7537	predicted gene 7537	121732	0.06
chr4_53831209_53831360	0.41	Tmem38b	transmembrane protein 38B	5227	0.18
chr16_93333790_93334136	0.41	1810053B23Rik	RIKEN cDNA 1810053B23 gene	19226	0.18
chr1_51771568_51771719	0.41	Myo1b	myosin IB	764	0.68
chr5_23851090_23851367	0.40	2700038G22Rik	RIKEN cDNA 2700038G22 gene	627	0.43
chr6_35891100_35891251	0.40	Gm43442	predicted gene 43442	35536	0.21
chr18_67396316_67396476	0.40	Tubb6	tubulin, beta 6 class V	4129	0.18
chr9_31032168_31032351	0.40	Gm29724	predicted gene, 29724	1054	0.42
chr1_107837922_107838109	0.40	Gm22438	predicted gene, 22438	54959	0.12
chr14_68304879_68305239	0.40	Gm47212	predicted gene, 47212	86806	0.08
chr16_4903733_4903884	0.40	Mgrn1	mahogunin, ring finger 1	9403	0.11
chr6_37509729_37509916	0.40	Akr1d1	aldo-keto reductase family 1, member D1	20351	0.21
chr10_53597848_53598018	0.40	Asf1a	anti-silencing function 1A histone chaperone	176	0.62
chr14_20942653_20942823	0.40	Vcl	vinculin	13340	0.21
chr5_66094198_66094378	0.39	Rbm47	RNA binding motif protein 47	3903	0.15
chr14_25566105_25566292	0.39	Mir3075	microRNA 3075	31759	0.14
chr10_89471287_89471467	0.39	Gas2l3	growth arrest-specific 2 like 3	27410	0.18
chr16_77028820_77029067	0.39	Usp25	ubiquitin specific peptidase 25	15156	0.21
chr1_67132947_67133268	0.39	Cps1	carbamoyl-phosphate synthetase 1	10081	0.24
chr5_96304478_96304629	0.39	Fras1	Fraser extracellular matrix complex subunit 1	69402	0.11
chr5_103756319_103756825	0.39	Aff1	AF4/FMR2 family, member 1	1999	0.36
chr5_122302844_122303082	0.39	Gm15842	predicted gene 15842	541	0.64
chr10_13985883_13986077	0.39	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	18956	0.19
chr13_75343113_75343287	0.39	Gm48234	predicted gene, 48234	136187	0.04
chr12_115253047_115253223	0.39	Ighv8-7	immunoglobulin heavy variable V8-7	5297	0.13
chr2_155384637_155384803	0.38	Trp53inp2	transformation related protein 53 inducible nuclear protein 2	2518	0.2
chr12_105010534_105010685	0.38	Syne3	spectrin repeat containing, nuclear envelope family member 3	800	0.47
chr1_67192772_67192960	0.38	Gm15668	predicted gene 15668	56334	0.12
chr1_85165585_85165793	0.38	Gm6264	predicted gene 6264	4826	0.12
chr7_134177162_134177350	0.38	Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	4312	0.28
chr1_67197806_67198015	0.38	Gm15668	predicted gene 15668	51290	0.13
chr5_63785642_63785801	0.38	Nwd2	NACHT and WD repeat domain containing 2	14741	0.2
chr14_47294893_47295081	0.38	Mapk1ip1l	mitogen-activated protein kinase 1 interacting protein 1-like	3279	0.11
chr1_40236870_40237279	0.38	Gm38070	predicted gene, 38070	946	0.59
chr1_30941324_30941475	0.38	Ptp4a1	protein tyrosine phosphatase 4a1	2905	0.22
chr1_90406755_90406922	0.38	Gm28722	predicted gene 28722	47663	0.14
chr19_31898515_31898680	0.37	Gm19241	predicted gene, 19241	15047	0.2
chr3_94937153_94937304	0.37	Selenbp1	selenium binding protein 1	4069	0.11
chr4_120465821_120465983	0.37	Scmh1	sex comb on midleg homolog 1	3822	0.27
chr15_10692675_10692891	0.37	Rai14	retinoic acid induced 14	20757	0.18
chr12_33322666_33322818	0.37	Atxn7l1	ataxin 7-like 1	7337	0.21
chr4_148590620_148590972	0.37	Srm	spermidine synthase	707	0.49
chr8_105256075_105256226	0.37	B3gnt9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	997	0.26
chr14_103345623_103346410	0.37	Mycbp2	MYC binding protein 2, E3 ubiquitin protein ligase	402	0.87
chr5_92363350_92363571	0.37	Cxcl11	chemokine (C-X-C motif) ligand 11	183	0.73
chr3_51185131_51185304	0.37	Noct	nocturnin	39230	0.12
chr3_89907720_89908002	0.37	Gm42809	predicted gene 42809	5055	0.12
chr4_82387767_82387965	0.37	n-R5s188	nuclear encoded rRNA 5S 188	51544	0.16
chr6_3979529_3979680	0.37	Tfpi2	tissue factor pathway inhibitor 2	9254	0.17
chr14_120256809_120256970	0.37	Mbnl2	muscleblind like splicing factor 2	18780	0.23
chr9_61309836_61310197	0.37	B930092H01Rik	RIKEN cDNA B930092H01 gene	16207	0.2
chr14_51289465_51289616	0.36	Gm49245	predicted gene, 49245	11938	0.1
chr10_80329677_80330103	0.36	Reep6	receptor accessory protein 6	63	0.81
chr8_95713972_95714123	0.36	Setd6	SET domain containing 6	1834	0.18
chr7_101341850_101342021	0.36	Stard10	START domain containing 10	567	0.58
chr13_50595486_50595664	0.36	Mir683-2	microRNA 683-2	5505	0.18
chr1_132321734_132321885	0.36	Nuak2	NUAK family, SNF1-like kinase, 2	5644	0.13
chr4_156101260_156101624	0.36	9430015G10Rik	RIKEN cDNA 9430015G10 gene	8540	0.09
chr17_86782105_86782256	0.36	Gm50008	predicted gene, 50008	8910	0.19
chr10_67193123_67193531	0.36	Jmjd1c	jumonji domain containing 1C	7574	0.21
chr13_20512020_20512224	0.36	Gm47657	predicted gene, 47657	7327	0.18
chr10_59778191_59778342	0.36	Micu1	mitochondrial calcium uptake 1	15853	0.14
chr6_116980697_116980886	0.35	Gm43929	predicted gene, 43929	1228	0.53
chr11_50386714_50386865	0.35	Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	1826	0.26
chr9_45294208_45294524	0.35	Gm47964	predicted gene, 47964	7596	0.11
chr18_75661611_75661825	0.35	Ctif	CBP80/20-dependent translation initiation factor	24445	0.23
chr4_109867828_109867979	0.35	Faf1	Fas-associated factor 1	27118	0.21
chr11_6050885_6051066	0.35	Camk2b	calcium/calmodulin-dependent protein kinase II, beta	14563	0.17
chr12_41246808_41247005	0.35	Gm47376	predicted gene, 47376	101184	0.07
chr2_80638968_80639507	0.35	Nup35	nucleoporin 35	27	0.96
chr11_5096900_5097277	0.35	Rhbdd3	rhomboid domain containing 3	1838	0.21
chr12_104109060_104109241	0.35	Gm23289	predicted gene, 23289	133	0.92
chr5_114606575_114606726	0.35	Trpv4	transient receptor potential cation channel, subfamily V, member 4	23988	0.13
chr17_59337097_59337380	0.35	Gm23769	predicted gene, 23769	111395	0.07
chr4_106569653_106569964	0.35	Dhcr24	24-dehydrocholesterol reductase	8770	0.11
chr2_6388723_6389074	0.35	Usp6nl	USP6 N-terminal like	32024	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Barhl2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.3	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.3	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.4	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.1	0.3	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1	0.4	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.2	GO:0002339	B cell selection(GO:0002339)
0.1	0.2	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.3	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	0.2	GO:0030070	insulin processing(GO:0030070)
0.1	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.2	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.4	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.2	GO:0006549	isoleucine metabolic process(GO:0006549)
0.1	0.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.2	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.3	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.2	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.1	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.2	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.5	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.3	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.0	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.3	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.3	GO:0002666	positive regulation of T cell tolerance induction(GO:0002666)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.3	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0	0.2	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.2	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.2	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.2	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.1	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.3	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.0	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.1	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.3	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0036476	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.2	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.3	GO:0042407	cristae formation(GO:0042407)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.0	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.0	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.1	GO:0097503	sialylation(GO:0097503)
0.0	0.3	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.0	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.3	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.2	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.0	GO:0010958	regulation of amino acid import(GO:0010958)
0.0	0.0	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.0	0.1	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.0	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.0	GO:0040038	polar body extrusion after meiotic divisions(GO:0040038)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.2	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.3	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.2	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887) negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.0	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.1	GO:0045714	low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.0	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0051136	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.2	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.0	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.1	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.0	0.1	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.1	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.0	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.0	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
0.0	0.0	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.2	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.0	GO:0043091	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0	0.0	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.0	GO:0003195	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.0	0.0	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.1	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.0	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.1	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.2	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.0	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.0	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.1	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.0	GO:1901671	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.0	GO:2001182	regulation of interleukin-12 secretion(GO:2001182)
0.0	0.1	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.0	GO:2000589	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.0	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.0	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.1	GO:0048242	epinephrine secretion(GO:0048242)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.2	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.0	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.0	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.0	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.0	0.0	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.1	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.0	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.1	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.2	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.0	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.1	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0045298	tubulin complex(GO:0045298)
0.1	0.5	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.1	0.3	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.1	0.4	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.2	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.2	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.4	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:1990696	USH2 complex(GO:1990696)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.3	GO:0071565	nBAF complex(GO:0071565)
0.0	0.3	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.0	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	2.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.0	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.0	GO:0098536	deuterosome(GO:0098536)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0005720	nuclear heterochromatin(GO:0005720)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.2	GO:0038181	bile acid receptor activity(GO:0038181)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.2	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.3	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.3	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.2	GO:0032564	dATP binding(GO:0032564)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.2	GO:0070191	methionine-R-sulfoxide reductase activity(GO:0070191)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.2	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0034806	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.2	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.0	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.3	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.2	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.0	GO:0016419	S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0016649	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.0	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.4	GO:0016749	N-succinyltransferase activity(GO:0016749)
0.0	0.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.0	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.0	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.0	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.3	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.5	PID AURORA A PATHWAY	Aurora A signaling
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	PID ARF 3PATHWAY	Arf1 pathway
0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.9	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	REACTOME KINESINS	Genes involved in Kinesins
0.5	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly