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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Batf3

Z-value: 0.69

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Transcription factors associated with Batf3

Gene Symbol	Gene ID	Gene Info
Batf3 Ensembl NCBI MGI UniProt	ENSMUSG00000026630.4	Batf3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Batf3	chr1_191092186_191092358	5575	0.118448	0.60	2.0e-01	Click!

Activity of the Batf3 motif across conditions

Conditions sorted by the z-value of the Batf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_19933617_19933791	0.80	Igsf23	immunoglobulin superfamily, member 23	11194	0.07
chr11_7201515_7201726	0.70	Igfbp1	insulin-like growth factor binding protein 1	3838	0.2
chr13_113168399_113168569	0.66	Gzmk	granzyme K	12413	0.12
chr11_109733399_109733703	0.66	Fam20a	family with sequence similarity 20, member A	11272	0.17
chr10_94882831_94882985	0.65	Gm48718	predicted gene, 48718	884	0.59
chr9_43708878_43709035	0.58	Gm30015	predicted gene, 30015	12041	0.15
chr12_82225847_82226035	0.55	Sipa1l1	signal-induced proliferation-associated 1 like 1	30644	0.19
chr7_71872986_71873347	0.52	4930441H08Rik	RIKEN cDNA 4930441H08 gene	36527	0.18
chr15_91103922_91104096	0.51	Gm7167	predicted gene 7167	25888	0.16
chr15_66911047_66911248	0.50	Ccn4	cellular communication network factor 4	1836	0.32
chr4_150512381_150512639	0.49	Rere	arginine glutamic acid dipeptide (RE) repeats	24117	0.2
chr6_54117349_54117506	0.48	Chn2	chimerin 2	19707	0.18
chr16_28881932_28882083	0.47	Mb21d2	Mab-21 domain containing 2	45640	0.17
chr12_109988471_109988667	0.46	Gm34667	predicted gene, 34667	35304	0.09
chrX_162902296_162902497	0.45	Ctps2	cytidine 5'-triphosphate synthase 2	225	0.89
chr9_124424931_124425085	0.43	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	854	0.55
chr3_130696475_130696626	0.42	Ostc	oligosaccharyltransferase complex subunit (non-catalytic)	72	0.96
chr6_120807534_120807700	0.41	Atp6v1e1	ATPase, H+ transporting, lysosomal V1 subunit E1	5195	0.15
chr5_142960238_142960403	0.39	Fscn1	fascin actin-bundling protein 1	23	0.97
chr2_4919371_4919703	0.37	Phyh	phytanoyl-CoA hydroxylase	457	0.76
chr10_108333685_108334010	0.37	Pawr	PRKC, apoptosis, WT1, regulator	1030	0.57
chr1_180422529_180422728	0.37	Stum	mechanosensory transduction mediator	39984	0.1
chr2_32167931_32168112	0.37	Gm27805	predicted gene, 27805	5150	0.13
chr17_35251426_35251588	0.35	Mir8094	microRNA 8094	218	0.76
chr6_86669367_86669537	0.35	Mxd1	MAX dimerization protein 1	291	0.82
chr2_125470672_125470852	0.33	Gm9913	predicted gene 9913	34327	0.17
chr15_69041867_69042024	0.32	Gm49422	predicted gene, 49422	82414	0.1
chr9_79213145_79213400	0.31	Gm47499	predicted gene, 47499	11265	0.17
chr5_65955908_65956072	0.31	4930480C01Rik	RIKEN cDNA 4930480C01 gene	4685	0.12
chr6_86472269_86472431	0.31	C87436	expressed sequence C87436	8310	0.08
chr18_12786708_12786879	0.29	Osbpl1a	oxysterol binding protein-like 1A	19656	0.15
chr5_122636983_122637314	0.29	P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	6763	0.14
chr5_32195986_32196216	0.28	Gm9555	predicted gene 9555	10604	0.15
chr2_71327268_71327425	0.28	Slc25a12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	1494	0.38
chr17_84119689_84119859	0.28	Gm19696	predicted gene, 19696	16186	0.15
chr1_155050256_155050434	0.27	Gm29282	predicted gene 29282	6834	0.17
chr5_123854435_123854768	0.27	Hcar2	hydroxycarboxylic acid receptor 2	10898	0.13
chr17_26538205_26538356	0.27	Gm50275	predicted gene, 50275	53	0.95
chr16_13354001_13354171	0.27	Mrtfb	myocardin related transcription factor B	4335	0.25
chr12_71045001_71045164	0.27	Arid4a	AT rich interactive domain 4A (RBP1-like)	3259	0.22
chr12_75307960_75308125	0.26	Rhoj	ras homolog family member J	280	0.95
chr2_29828898_29829065	0.26	Urm1	ubiquitin related modifier 1	1586	0.22
chr15_78450182_78450345	0.26	Tmprss6	transmembrane serine protease 6	5884	0.11
chr3_127553258_127553423	0.26	Larp7	La ribonucleoprotein domain family, member 7	7	0.64
chr15_62169758_62169909	0.26	Pvt1	Pvt1 oncogene	8342	0.27
chr15_76579147_76579305	0.26	Gm49413	predicted gene, 49413	1401	0.18
chr10_3573083_3573240	0.25	Iyd	iodotyrosine deiodinase	32873	0.22
chr15_66932473_66932630	0.25	Ndrg1	N-myc downstream regulated gene 1	1918	0.28
chr11_19924205_19924473	0.25	Spred2	sprouty-related EVH1 domain containing 2	36	0.99
chrX_13070891_13071062	0.24	Usp9x	ubiquitin specific peptidase 9, X chromosome	522	0.79
chr11_60133979_60134158	0.24	Rai1	retinoic acid induced 1	6014	0.16
chr10_63122682_63122839	0.23	Mypn	myopalladin	76	0.96
chr5_134555490_134555833	0.23	Gm42884	predicted gene 42884	876	0.4
chr14_26217468_26217634	0.23	Gm19015	predicted gene, 19015	2359	0.19
chr11_98785850_98786019	0.23	Msl1	male specific lethal 1	9582	0.09
chr14_25938104_25938268	0.23	Cphx1	cytoplasmic polyadenylated homeobox 1	118	0.94
chr14_26077857_26078021	0.23	Gm19014	predicted gene, 19014	2357	0.16
chr9_102718313_102718471	0.22	Amotl2	angiomotin-like 2	37	0.96
chr4_141301124_141301279	0.22	Epha2	Eph receptor A2	39	0.96
chr17_33760685_33760872	0.22	Rab11b	RAB11B, member RAS oncogene family	248	0.75
chr6_120932679_120932852	0.22	Mical3	microtubule associated monooxygenase, calponin and LIM domain containing 3	2770	0.17
chr11_94044111_94044443	0.22	Spag9	sperm associated antigen 9	9	0.98
chr13_56461581_56461925	0.22	Il9	interleukin 9	20493	0.14
chr13_51871249_51871406	0.22	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	24583	0.2
chr12_84279002_84279173	0.21	Ptgr2	prostaglandin reductase 2	6145	0.12
chr10_19948695_19948879	0.21	Map3k5	mitogen-activated protein kinase kinase kinase 5	2268	0.33
chr1_75168548_75168709	0.21	Zfand2b	zinc finger, AN1 type domain 2B	18	0.93
chr4_133928748_133928902	0.21	Hmgn2	high mobility group nucleosomal binding domain 2	38418	0.08
chr9_103234188_103234350	0.21	Trf	transferrin	3825	0.2
chr13_22043005_22043165	0.21	H2bc11	H2B clustered histone 11	129	0.45
chr14_25346096_25346426	0.21	Gm26660	predicted gene, 26660	32374	0.17
chr16_52034396_52034559	0.20	Cblb	Casitas B-lineage lymphoma b	2260	0.37
chr16_10976237_10976411	0.20	Litaf	LPS-induced TN factor	745	0.51
chr9_43545212_43545661	0.20	Gm36855	predicted gene, 36855	24432	0.17
chr17_28013343_28013511	0.20	Anks1	ankyrin repeat and SAM domain containing 1	6082	0.13
chr6_124811055_124811230	0.19	Tpi1	triosephosphate isomerase 1	744	0.35
chr5_139484483_139484643	0.19	Zfand2a	zinc finger, AN1-type domain 2A	14	0.97
chr16_38940739_38940891	0.19	Gm22500	predicted gene, 22500	13606	0.21
chr8_108743266_108743566	0.18	Gm38042	predicted gene, 38042	5823	0.26
chr18_74120787_74120938	0.18	Mapk4	mitogen-activated protein kinase 4	55503	0.1
chr15_36960415_36960763	0.18	Gm34590	predicted gene, 34590	21725	0.14
chr5_73168897_73169054	0.18	Fryl	FRY like transcription coactivator	535	0.7
chr9_55333127_55333288	0.18	Tmem266	transmembrane protein 266	6	0.98
chr17_56476460_56476653	0.18	Ptprs	protein tyrosine phosphatase, receptor type, S	73	0.96
chr7_45526245_45526410	0.18	Plekha4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	3	0.51
chr8_88633569_88633732	0.17	Snx20	sorting nexin 20	2451	0.26
chr9_118674269_118674608	0.17	Itga9	integrin alpha 9	11397	0.23
chr15_3268359_3268542	0.17	Selenop	selenoprotein P	97	0.97
chr7_138846212_138846376	0.17	Mapk1ip1	mitogen-activated protein kinase 1 interacting protein 1	21	0.53
chr2_103846113_103846314	0.17	Gm13879	predicted gene 13879	2557	0.13
chr11_115462203_115462381	0.17	Slc16a5	solute carrier family 16 (monocarboxylic acid transporters), member 5	182	0.83
chr1_184852008_184852353	0.16	Mtarc2	mitochondrial amidoxime reducing component 2	5729	0.17
chr10_82354496_82354666	0.16	Gm4924	predicted gene 4924	265	0.91
chr3_13783011_13783180	0.16	Ralyl	RALY RNA binding protein-like	6247	0.24
chr12_54459633_54459834	0.16	Gm7557	predicted gene 7557	29335	0.13
chr17_29599607_29599789	0.16	Tbc1d22bos	TBC1 domain family, member 22B, opposite strand	3393	0.11
chr6_128799347_128799643	0.16	Klrb1c	killer cell lectin-like receptor subfamily B member 1C	10280	0.1
chr3_129536318_129536484	0.15	Gm43072	predicted gene 43072	1740	0.29
chr4_155235347_155235531	0.15	Ski	ski sarcoma viral oncogene homolog (avian)	12847	0.15
chr8_69192982_69193338	0.15	Lzts1	leucine zipper, putative tumor suppressor 1	8935	0.15
chr19_43898660_43898822	0.15	Dnmbp	dynamin binding protein	8050	0.14
chr14_77034577_77034753	0.15	Lacc1	laccase domain containing 1	1416	0.39
chr5_130081319_130081518	0.15	Tpst1	protein-tyrosine sulfotransferase 1	2048	0.24
chr10_75121130_75121291	0.15	Bcr	BCR activator of RhoGEF and GTPase	39150	0.15
chr16_30732879_30733030	0.15	Gm49754	predicted gene, 49754	60301	0.1
chr2_58794623_58794807	0.15	Upp2	uridine phosphorylase 2	29390	0.17
chr15_66996996_66997162	0.15	Ndrg1	N-myc downstream regulated gene 1	27439	0.15
chr14_68048482_68048633	0.15	Gm31107	predicted gene, 31107	2773	0.28
chr17_73881220_73881413	0.14	Xdh	xanthine dehydrogenase	5434	0.2
chr2_133550506_133550686	0.14	Bmp2	bone morphogenetic protein 2	1563	0.4
chr13_23530925_23531217	0.14	H4c8	H4 clustered histone 8	21	0.59
chr5_123980690_123981011	0.14	Hip1r	huntingtin interacting protein 1 related	596	0.59
chr4_40703144_40703305	0.14	Aptx	aprataxin	30	0.96
chr1_155063987_155064316	0.14	Gm29282	predicted gene 29282	6972	0.17
chr9_106170725_106171009	0.14	Wdr82	WD repeat domain containing 82	61	0.94
chr11_112821671_112821851	0.13	4933434M16Rik	RIKEN cDNA 4933434M16 gene	3393	0.25
chr15_81190841_81191005	0.13	4930483J18Rik	RIKEN cDNA 4930483J18 gene	70	0.63
chr2_125123073_125123271	0.13	Myef2	myelin basic protein expression factor 2, repressor	242	0.89
chr8_127440670_127440852	0.13	Pard3	par-3 family cell polarity regulator	6985	0.31
chr5_24383598_24383768	0.13	Gm15587	predicted gene 15587	69	0.93
chr11_121086049_121086611	0.13	Sectm1a	secreted and transmembrane 1A	5110	0.09
chr6_115465780_115466186	0.13	Gm44079	predicted gene, 44079	993	0.54
chrX_104293728_104293906	0.12	Vcp-rs	valosin containing protein, related sequence	54417	0.12
chr13_19622939_19623114	0.12	Sfrp4	secreted frizzled-related protein 4	78	0.97
chr8_3414105_3414577	0.12	Arhgef18	rho/rac guanine nucleotide exchange factor (GEF) 18	12359	0.15
chrX_168941822_168941984	0.12	Arhgap6	Rho GTPase activating protein 6	94708	0.08
chr17_34119461_34119627	0.12	H2-DMa	histocompatibility 2, class II, locus DMa	3	0.87
chr14_20226275_20226463	0.12	Gm48395	predicted gene, 48395	10867	0.12
chr6_17532117_17532312	0.11	Met	met proto-oncogene	2787	0.33
chr13_55425993_55426169	0.11	F12	coagulation factor XII (Hageman factor)	698	0.47
chr13_67306400_67306560	0.11	Zfp457	zinc finger protein 457	5	0.94
chr6_134160918_134161473	0.11	Gm17088	predicted gene 17088	10812	0.2
chr5_123436059_123436381	0.11	Mlxip	MLX interacting protein	9819	0.09
chr17_65701951_65702157	0.11	Gm49867	predicted gene, 49867	40476	0.12
chr19_61226557_61226761	0.11	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	24	0.96
chrY_2644529_2644731	0.11	Uba1y-ps1	ubiquitin-activating enzyme, Chr Y, pseudogene 1	2670	0.2
chr17_72399518_72399681	0.11	Gm24736	predicted gene, 24736	99819	0.07
chrX_106190211_106190376	0.11	Pgk1	phosphoglycerate kinase 1	1335	0.35
chr5_100583214_100583366	0.10	Gm43510	predicted gene 43510	9466	0.14
chr3_21935997_21936168	0.10	Gm43674	predicted gene 43674	62386	0.12
chr11_102742573_102742724	0.10	Gm16342	predicted gene 16342	10243	0.11
chr15_7137772_7137928	0.10	Lifr	LIF receptor alpha	2692	0.38
chrY_2681513_2681716	0.10	Gm18798	predicted gene, 18798	2670	0.2
chr8_70213088_70213257	0.10	Slc25a42	solute carrier family 25, member 42	867	0.42
chr9_107612764_107612937	0.10	Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	3197	0.08
chr1_86606018_86606363	0.10	Cops7b	COP9 signalosome subunit 7B	9450	0.12
chr2_109280667_109280830	0.10	Mettl15	methyltransferase like 15	0	0.5
chrX_101953814_101953986	0.10	Nhsl2	NHS-like 2	7897	0.18
chr11_116657951_116658105	0.10	Prcd	photoreceptor disc component	872	0.37
chr19_29037790_29038010	0.10	1700018L02Rik	RIKEN cDNA 1700018L02 gene	8345	0.11
chr1_131079599_131079858	0.10	Gm25549	predicted gene, 25549	5977	0.14
chr5_36691549_36691700	0.10	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed	4313	0.16
chr16_34939309_34939471	0.10	1700119H24Rik	RIKEN cDNA 1700119H24 gene	61	0.97
chr2_158316475_158316655	0.10	Lbp	lipopolysaccharide binding protein	2359	0.18
chr2_38111461_38111697	0.10	Gm44291	predicted gene, 44291	4283	0.25
chr7_16119633_16119956	0.10	Kptn	kaptin	101	0.95
chr7_100591363_100591708	0.10	Mrpl48	mitochondrial ribosomal protein L48	109	0.93
chr7_44672289_44672471	0.10	Myh14	myosin, heavy polypeptide 14	1537	0.22
chr15_86189223_86189384	0.10	Cerk	ceramide kinase	3162	0.2
chr17_34586879_34587070	0.10	Notch4	notch 4	29	0.91
chr19_38365309_38365465	0.10	Gm50155	predicted gene, 50155	20127	0.13
chr12_79561056_79561219	0.09	Rad51b	RAD51 paralog B	233784	0.02
chr16_93710965_93711118	0.09	Dop1b	DOP1 leucine zipper like protein B	863	0.55
chr4_142017836_142017987	0.09	4930455G09Rik	RIKEN cDNA 4930455G09 gene	13	0.96
chr11_20200974_20201192	0.09	Rab1a	RAB1A, member RAS oncogene family	349	0.85
chr6_128764252_128764459	0.09	Gm43907	predicted gene, 43907	19711	0.09
chr1_161035922_161036116	0.09	Gas5	growth arrest specific 5	1	0.38
chr4_107303606_107303802	0.09	Dio1	deiodinase, iodothyronine, type I	3362	0.15
chr11_69417573_69417747	0.09	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	3985	0.1
chr8_69716419_69716582	0.09	Zfp869	zinc finger protein 869	14	0.97
chr9_121348150_121348320	0.09	Gm47092	predicted gene, 47092	1679	0.32
chr18_38962798_38962983	0.09	Gm5820	predicted gene 5820	7181	0.19
chr13_34077943_34078110	0.09	Tubb2a	tubulin, beta 2A class IIA	19	0.96
chr2_127444501_127444657	0.09	Fahd2a	fumarylacetoacetate hydrolase domain containing 2A	14	0.97
chr11_88242033_88242214	0.09	Gm38534	predicted gene, 38534	11245	0.17
chr7_16296893_16297072	0.09	Ccdc9	coiled-coil domain containing 9	10187	0.11
chr5_134269920_134270079	0.09	Gm43481	predicted gene 43481	737	0.54
chr10_18237308_18237472	0.09	Gm10827	predicted gene 10827	2024	0.26
chr16_55698500_55698846	0.09	Gm19771	predicted gene, 19771	41245	0.16
chr4_59177698_59177849	0.09	Ugcg	UDP-glucose ceramide glucosyltransferase	11484	0.15
chr7_145111866_145112053	0.09	Gm45181	predicted gene 45181	51037	0.14
chr2_120154260_120154763	0.09	Ehd4	EH-domain containing 4	49	0.97
chr9_100599823_100599989	0.09	Stag1	stromal antigen 1	2108	0.23
chr5_123057781_123058133	0.09	Gm6444	predicted gene 6444	8285	0.09
chr15_99116561_99116759	0.09	Spats2	spermatogenesis associated, serine-rich 2	9256	0.09
chr4_155895345_155895496	0.08	Acap3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	3108	0.1
chr10_81182793_81182961	0.08	Dapk3	death-associated protein kinase 3	128	0.84
chr2_75763382_75763582	0.08	Gm13657	predicted gene 13657	13706	0.14
chr10_108360046_108360218	0.08	Gm23105	predicted gene, 23105	3533	0.25
chr19_47317600_47317752	0.08	Sh3pxd2a	SH3 and PX domains 2A	2925	0.24
chr7_7298727_7298897	0.08	Clcn4	chloride channel, voltage-sensitive 4	6	0.55
chr10_121510171_121510329	0.08	Gm35696	predicted gene, 35696	148	0.93
chr9_124424253_124424419	0.08	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	182	0.93
chr18_3281039_3281202	0.08	Crem	cAMP responsive element modulator	12	0.98
chr4_128610093_128610254	0.08	Zscan20	zinc finger and SCAN domains 20	75	0.97
chr16_57181297_57181460	0.07	Tbc1d23	TBC1 domain family, member 23	1174	0.41
chr6_114890473_114890633	0.07	Vgll4	vestigial like family member 4	15446	0.2
chr11_61274046_61274219	0.07	Aldh3a2	aldehyde dehydrogenase family 3, subfamily A2	6668	0.17
chr3_96094342_96094503	0.07	Gm43554	predicted gene 43554	7551	0.1
chr3_104677278_104677438	0.07	Gm29560	predicted gene 29560	7348	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030035	microspike assembly(GO:0030035)
0.1	0.2	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1	0.2	GO:0048320	axial mesoderm formation(GO:0048320)
0.1	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.2	GO:0045054	constitutive secretory pathway(GO:0045054)
0.1	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.2	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.2	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	0.3	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	0.1	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0002254	kinin cascade(GO:0002254)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.4	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.0	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:1901642	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.0	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.1	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.2	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.1	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0071335	hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336)
0.0	0.0	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0044393	microspike(GO:0044393)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.0	GO:0033269	internode region of axon(GO:0033269)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	GO:0045503	dynein light chain binding(GO:0045503)
0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo