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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Bbx

Z-value: 1.08

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Transcription factors associated with Bbx

Gene Symbol	Gene ID	Gene Info
Bbx Ensembl NCBI MGI UniProt	ENSMUSG00000022641.9	Bbx

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Bbx	chr16_50431377_50431947	647	0.811981	-0.87	2.3e-02	Click!
Bbx	chr16_50429243_50429410	586	0.837552	-0.86	2.6e-02	Click!
Bbx	chr16_50432097_50432257	132	0.977663	-0.70	1.2e-01	Click!
Bbx	chr16_50430297_50430475	474	0.881324	-0.58	2.3e-01	Click!
Bbx	chr16_50364236_50364416	33333	0.229106	0.53	2.8e-01	Click!

Activity of the Bbx motif across conditions

Conditions sorted by the z-value of the Bbx motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_105328178_105328374	0.97	Gm12722	predicted gene 12722	46670	0.19
chr13_4468232_4468415	0.65	Gm48010	predicted gene, 48010	1757	0.34
chr11_16858925_16859117	0.65	Egfr	epidermal growth factor receptor	19129	0.18
chr16_43515591_43515742	0.61	Zbtb20	zinc finger and BTB domain containing 20	5358	0.27
chr11_16834271_16834692	0.61	Egfros	epidermal growth factor receptor, opposite strand	3779	0.26
chr7_87371467_87371654	0.55	Tyr	tyrosinase	121832	0.05
chr16_23056284_23056437	0.48	Kng1	kininogen 1	1505	0.19
chr7_89669589_89669767	0.44	A230065N10Rik	RIKEN cDNA A230065N10 gene	36554	0.13
chr11_16860515_16860728	0.44	Egfr	epidermal growth factor receptor	17529	0.19
chr8_76152114_76152295	0.42	Gm45742	predicted gene 45742	35177	0.2
chr6_93395998_93396170	0.42	Gm44181	predicted gene, 44181	59473	0.12
chr13_62860030_62860181	0.41	Fbp2	fructose bisphosphatase 2	1683	0.26
chr10_99314465_99314820	0.41	B530045E10Rik	RIKEN cDNA B530045E10 gene	15476	0.14
chr10_99313401_99313555	0.38	B530045E10Rik	RIKEN cDNA B530045E10 gene	14312	0.14
chr9_74891211_74891440	0.36	Onecut1	one cut domain, family member 1	24841	0.14
chr2_8116897_8117048	0.36	Gm13254	predicted gene 13254	30893	0.26
chr8_64735601_64735761	0.35	Msmo1	methylsterol monoxygenase 1	1889	0.29
chr8_44709672_44709838	0.35	Gm26089	predicted gene, 26089	107922	0.07
chr4_52816035_52816203	0.30	Olfr275	olfactory receptor 275	1515	0.32
chr3_112820887_112821047	0.30	Gm43587	predicted gene 43587	53955	0.17
chr10_87549648_87549853	0.30	Pah	phenylalanine hydroxylase	3077	0.29
chr16_14950695_14950883	0.30	Gm33696	predicted gene, 33696	41094	0.14
chr3_98670706_98671055	0.29	Gm12399	predicted gene 12399	7451	0.14
chr3_27766821_27766972	0.29	Fndc3b	fibronectin type III domain containing 3B	55589	0.14
chr1_67153015_67153221	0.29	Cps1	carbamoyl-phosphate synthetase 1	30092	0.19
chr5_33465811_33466048	0.29	Gm43851	predicted gene 43851	28465	0.15
chr11_16589151_16589356	0.29	Gm12663	predicted gene 12663	46813	0.12
chrX_19139471_19139640	0.28	Mir221	microRNA 221	6833	0.2
chr8_72131379_72131550	0.28	Tpm4	tropomyosin 4	1290	0.23
chr14_22964972_22965155	0.28	Gm47601	predicted gene, 47601	37137	0.22
chr13_64205035_64205186	0.28	Cdc14b	CDC14 cell division cycle 14B	4072	0.13
chr3_19043040_19043218	0.28	Gm37979	predicted gene, 37979	100770	0.07
chrX_61144273_61144442	0.27	Gm24396	predicted gene, 24396	1005	0.5
chr2_73974269_73974420	0.27	Gm13668	predicted gene 13668	13675	0.22
chr16_32165698_32165859	0.26	Nrros	negative regulator of reactive oxygen species	184	0.92
chr11_16877316_16877467	0.26	Egfr	epidermal growth factor receptor	759	0.68
chr1_127898839_127898990	0.26	Rab3gap1	RAB3 GTPase activating protein subunit 1	1999	0.31
chr10_52234541_52234692	0.26	Dcbld1	discoidin, CUB and LCCL domain containing 1	979	0.54
chr10_68126588_68126805	0.26	Arid5b	AT rich interactive domain 5B (MRF1-like)	9930	0.25
chr4_54733562_54733749	0.25	Gm12477	predicted gene 12477	63463	0.11
chr15_81804535_81804686	0.25	Tef	thyrotroph embryonic factor	1784	0.19
chr5_150264404_150264568	0.25	Fry	FRY microtubule binding protein	4719	0.21
chr8_114776777_114776930	0.24	Wwox	WW domain-containing oxidoreductase	64686	0.12
chr1_9578333_9578671	0.24	Gm6161	predicted gene 6161	3954	0.16
chr3_129526989_129527140	0.24	Gm35986	predicted gene, 35986	5045	0.17
chr7_68975121_68975306	0.23	Gm44691	predicted gene 44691	14191	0.21
chr8_45630758_45630927	0.23	Sorbs2	sorbin and SH3 domain containing 2	2641	0.27
chrX_35957374_35957532	0.23	Dock11	dedicator of cytokinesis 11	10056	0.25
chr7_4705237_4705398	0.23	Brsk1	BR serine/threonine kinase 1	3661	0.1
chr13_24546719_24546907	0.23	Ripor2	RHO family interacting cell polarization regulator 2	35376	0.14
chr5_8159085_8159252	0.23	Gm21759	predicted gene, 21759	20468	0.16
chr1_164586384_164586561	0.23	D630023O14Rik	RIKEN cDNA D630023O14 gene	11017	0.18
chr8_68016078_68016239	0.23	Gm22018	predicted gene, 22018	5818	0.26
chr19_56600920_56601157	0.23	Nhlrc2	NHL repeat containing 2	30241	0.15
chr1_102735468_102735657	0.23	Gm22034	predicted gene, 22034	217986	0.02
chr4_49535104_49535371	0.22	Aldob	aldolase B, fructose-bisphosphate	3629	0.16
chr19_8263388_8263539	0.22	Gm7105	predicted gene 7105	5876	0.17
chr2_42022610_42022815	0.22	Gm13461	predicted gene 13461	33883	0.23
chr16_23511406_23511565	0.22	Gm49514	predicted gene, 49514	2785	0.2
chr17_64961928_64962092	0.22	Gm25344	predicted gene, 25344	17158	0.25
chr19_26823641_26823967	0.22	4931403E22Rik	RIKEN cDNA 4931403E22 gene	103	0.97
chr6_146915387_146915718	0.21	Ppfibp1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	26963	0.13
chr16_87671512_87671714	0.21	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	27332	0.17
chr10_98666150_98666367	0.21	Gm5427	predicted gene 5427	33452	0.22
chr14_21281587_21281757	0.21	Adk	adenosine kinase	36453	0.2
chr16_3877520_3877678	0.21	Zfp597	zinc finger protein 597	5203	0.09
chr2_84338164_84338328	0.21	Gm13711	predicted gene 13711	19935	0.19
chr19_7966794_7966947	0.21	Slc22a27	solute carrier family 22, member 27	843	0.53
chr3_129297386_129297570	0.20	Enpep	glutamyl aminopeptidase	11556	0.16
chr12_75694445_75694598	0.20	Wdr89	WD repeat domain 89	24984	0.18
chr1_61971987_61972299	0.20	Gm29640	predicted gene 29640	9064	0.27
chr12_103657456_103657664	0.20	Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	348	0.79
chr13_63345488_63345639	0.20	Fancc	Fanconi anemia, complementation group C	6609	0.11
chr2_4933062_4933213	0.20	Phyh	phytanoyl-CoA hydroxylase	4346	0.15
chr2_155592205_155592416	0.20	Gssos1	glutathione synthase, opposite strand 1	9	0.7
chr5_74625167_74625318	0.20	Lnx1	ligand of numb-protein X 1	1721	0.35
chr17_64740112_64740263	0.20	Gm17133	predicted gene 17133	13909	0.19
chr7_79311533_79311809	0.19	Gm39041	predicted gene, 39041	12646	0.14
chr6_37751805_37751968	0.19	Atp6v0c-ps2	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2	54200	0.13
chr4_76942367_76942518	0.19	Gm11246	predicted gene 11246	15131	0.21
chr3_61092785_61092961	0.19	Gm37035	predicted gene, 37035	89087	0.08
chr11_16899488_16899646	0.19	Egfr	epidermal growth factor receptor	5618	0.21
chr2_46521470_46521692	0.19	Gm13470	predicted gene 13470	78871	0.1
chr13_28672871_28673024	0.18	Mir6368	microRNA 6368	37926	0.2
chr1_67201067_67201218	0.18	Gm15668	predicted gene 15668	48058	0.14
chr3_150365886_150366049	0.18	Gm6439	predicted gene 6439	150114	0.05
chr7_72181786_72181957	0.18	Mctp2	multiple C2 domains, transmembrane 2	19497	0.2
chr3_108902138_108902289	0.18	Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	3372	0.17
chr6_133973359_133973527	0.18	Gm8956	predicted gene 8956	41034	0.14
chr1_91442432_91442601	0.18	Per2	period circadian clock 2	7349	0.12
chr1_67014326_67014505	0.18	Lancl1	LanC (bacterial lantibiotic synthetase component C)-like 1	6650	0.2
chr2_147949593_147949773	0.18	9030622O22Rik	RIKEN cDNA 9030622O22 gene	26502	0.2
chr12_104087488_104087669	0.18	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	6929	0.1
chr18_47314660_47314858	0.18	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	18567	0.22
chr11_86705520_86705677	0.18	Cltc	clathrin, heavy polypeptide (Hc)	1901	0.3
chr1_52434736_52434915	0.18	Gm23460	predicted gene, 23460	9719	0.18
chr11_104549691_104549898	0.18	Cdc27	cell division cycle 27	598	0.47
chr15_7159645_7159840	0.18	Lifr	LIF receptor alpha	5389	0.3
chr13_4577869_4578048	0.18	Akr1c21	aldo-keto reductase family 1, member C21	801	0.61
chr6_28758962_28759125	0.17	Snd1	staphylococcal nuclease and tudor domain containing 1	5647	0.24
chr5_63938523_63938715	0.17	Rell1	RELT-like 1	7705	0.17
chr6_17172773_17172927	0.17	Gm4876	predicted gene 4876	1017	0.58
chr4_150280961_150281112	0.17	Rere	arginine glutamic acid dipeptide (RE) repeats	610	0.68
chr8_56233300_56233562	0.17	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	61154	0.13
chr4_63271316_63271493	0.17	Col27a1	collagen, type XXVII, alpha 1	11263	0.16
chr16_78631922_78632084	0.17	Gm24861	predicted gene, 24861	7256	0.22
chrX_11018346_11018497	0.17	Gm14485	predicted gene 14485	2586	0.39
chr9_32005362_32005542	0.17	Gm47465	predicted gene, 47465	8	0.97
chr3_24782580_24782752	0.17	Naaladl2	N-acetylated alpha-linked acidic dipeptidase-like 2	956	0.73
chr3_104220440_104221564	0.17	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	628	0.6
chrX_52147782_52148137	0.17	Gpc4	glypican 4	17293	0.27
chr11_101585925_101586098	0.17	Tmem106a	transmembrane protein 106A	14	0.94
chr10_95254224_95254433	0.17	Gm48880	predicted gene, 48880	60525	0.08
chr9_74894770_74895613	0.17	Onecut1	one cut domain, family member 1	28707	0.13
chr4_49435481_49435755	0.17	Acnat1	acyl-coenzyme A amino acid N-acyltransferase 1	15516	0.12
chr2_132638397_132638559	0.17	AU019990	expressed sequence AU019990	7403	0.13
chr7_5071633_5071806	0.16	U2af2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2	3689	0.08
chr7_59241435_59241594	0.16	Ube3a	ubiquitin protein ligase E3A	1394	0.16
chr11_16883025_16883203	0.16	Egfr	epidermal growth factor receptor	4964	0.23
chr12_119071015_119071241	0.16	Gm18921	predicted gene, 18921	3698	0.34
chr15_9602541_9602716	0.16	Il7r	interleukin 7 receptor	72452	0.11
chr12_78228003_78228154	0.16	Gphn	gephyrin	1425	0.29
chr2_84386945_84387393	0.16	Calcrl	calcitonin receptor-like	11811	0.2
chr1_169166546_169166738	0.16	Mir6354	microRNA 6354	147553	0.04
chr11_16885540_16885691	0.16	Egfr	epidermal growth factor receptor	7465	0.21
chr4_131041255_131041582	0.16	A930031H19Rik	RIKEN cDNA A930031H19 gene	30944	0.18
chr9_122807315_122807480	0.16	Tcaim	T cell activation inhibitor, mitochondrial	1794	0.25
chr9_61163963_61164339	0.16	I730028E13Rik	RIKEN cDNA I730028E13 gene	25636	0.14
chr11_44683144_44683318	0.16	Gm12158	predicted gene 12158	20555	0.2
chr4_57123440_57123604	0.16	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	3462	0.28
chrX_51399106_51399311	0.16	Gm14621	predicted gene 14621	159676	0.03
chr4_142221610_142221783	0.16	Kazn	kazrin, periplakin interacting protein	11490	0.22
chr3_16184013_16184168	0.15	Ythdf3	YTH N6-methyladenosine RNA binding protein 3	854	0.71
chr6_141856209_141856370	0.15	Slco1a4	solute carrier organic anion transporter family, member 1a4	90	0.97
chr8_105045983_105046145	0.15	Gm45725	predicted gene 45725	898	0.39
chr6_71193278_71193676	0.15	Fabp1	fatty acid binding protein 1, liver	6350	0.13
chr5_146224346_146224522	0.15	Rnf6	ring finger protein (C3H2C3 type) 6	2879	0.15
chr4_84540692_84540849	0.15	Bnc2	basonuclin 2	5520	0.32
chr9_109126916_109127177	0.15	Plxnb1	plexin B1	20252	0.09
chr1_50955186_50955338	0.15	Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	27743	0.19
chr4_3402550_3402701	0.15	Gm11784	predicted gene 11784	15779	0.19
chr7_102184013_102184287	0.15	Nup98	nucleoporin 98	585	0.66
chr13_44339412_44339567	0.15	Gm33958	predicted gene, 33958	51628	0.11
chr11_45255693_45255855	0.15	Gm12161	predicted gene 12161	25180	0.18
chr7_100367751_100367915	0.15	Ppme1	protein phosphatase methylesterase 1	245	0.89
chr9_37082260_37082465	0.15	Pknox2	Pbx/knotted 1 homeobox 2	917	0.53
chrX_108664177_108664328	0.14	Gm379	predicted gene 379	203	0.97
chr5_105353588_105353739	0.14	Gbp11	guanylate binding protein 11	7191	0.18
chrX_163768401_163768583	0.14	Rnf138rt1	ring finger protein 138, retrogene 1	7163	0.23
chr1_75342981_75343140	0.14	Des	desmin	17269	0.09
chr18_81321681_81321954	0.14	Gm30192	predicted gene, 30192	57109	0.13
chr2_94066434_94066607	0.14	Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	51	0.98
chr8_41473406_41473602	0.14	Frg1	FSHD region gene 1	56430	0.14
chr19_20723027_20723214	0.14	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	4442	0.3
chr16_43230215_43230536	0.14	Zbtb20	zinc finger and BTB domain containing 20	5505	0.24
chr2_109955276_109955427	0.14	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	20191	0.18
chr14_98816721_98816872	0.14	Gm27034	predicted gene, 27034	101983	0.06
chr5_36563902_36564053	0.14	Tbc1d14	TBC1 domain family, member 14	79	0.97
chrX_57010435_57010605	0.14	Brs3	bombesin-like receptor 3	32554	0.15
chr17_21534528_21534684	0.14	Zfp52	zinc finger protein 52	933	0.35
chr8_5030377_5030626	0.14	n-R5s93	nuclear encoded rRNA 5S 93	38876	0.14
chr1_4768744_4768905	0.14	Gm6123	predicted gene 6123	2307	0.18
chr10_112926082_112926233	0.14	Gm26596	predicted gene, 26596	2344	0.23
chr16_43532035_43532200	0.14	Zbtb20	zinc finger and BTB domain containing 20	21809	0.21
chr19_30241662_30241818	0.14	Mbl2	mannose-binding lectin (protein C) 2	8798	0.21
chr2_52576390_52576567	0.14	Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	17911	0.18
chr15_77151879_77152047	0.14	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	1593	0.31
chr3_98682461_98682815	0.13	Gm12399	predicted gene 12399	4307	0.16
chr15_38712864_38713163	0.13	Gm45924	predicted gene, 45924	15503	0.18
chr7_69980197_69980349	0.13	Gm24120	predicted gene, 24120	22369	0.2
chr2_67888984_67889171	0.13	Gm37964	predicted gene, 37964	9519	0.26
chr3_142777238_142777410	0.13	Gm24457	predicted gene, 24457	4248	0.14
chr11_93988000_93988159	0.13	Spag9	sperm associated antigen 9	8012	0.15
chrX_38452345_38452518	0.13	Lamp2	lysosomal-associated membrane protein 2	3983	0.21
chr1_164415069_164415280	0.13	Gm37411	predicted gene, 37411	9539	0.16
chr6_115465552_115465760	0.13	Gm44079	predicted gene, 44079	666	0.7
chr8_94594314_94594528	0.13	Fam192a	family with sequence similarity 192, member A	7130	0.12
chr3_80042843_80043016	0.13	A330069K06Rik	RIKEN cDNA A330069K06 gene	11963	0.22
chr7_118250628_118250799	0.13	4930583K01Rik	RIKEN cDNA 4930583K01 gene	6848	0.14
chr3_82036127_82036278	0.13	Gucy1b1	guanylate cyclase 1, soluble, beta 1	880	0.6
chr10_87931882_87932033	0.13	Tyms-ps	thymidylate synthase, pseudogene	34890	0.14
chr17_91875114_91875285	0.13	Gm41654	predicted gene, 41654	3060	0.27
chr5_96980131_96980330	0.13	Gm9484	predicted gene 9484	17134	0.11
chr4_105655884_105656063	0.13	Gm12726	predicted gene 12726	77633	0.11
chr13_64106036_64106228	0.13	Slc35d2	solute carrier family 35, member D2	1031	0.46
chr13_50815744_50815906	0.13	Gm2654	predicted gene 2654	29681	0.16
chr15_3608242_3608402	0.13	Gm22031	predicted gene, 22031	4925	0.27
chr6_48642896_48643049	0.13	Gimap8	GTPase, IMAP family member 8	4262	0.08
chr14_27673339_27673537	0.13	Erc2	ELKS/RAB6-interacting/CAST family member 2	20611	0.21
chr3_104273850_104274019	0.13	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	53560	0.08
chr16_57127831_57128340	0.13	Tomm70a	translocase of outer mitochondrial membrane 70A	6382	0.18
chr16_46833812_46833992	0.13	Gm6912	predicted gene 6912	240296	0.02
chr19_3194323_3194505	0.13	1700030N03Rik	RIKEN cDNA 1700030N03 gene	3284	0.14
chrX_85452459_85452626	0.13	Gm14765	predicted gene 14765	20715	0.24
chr16_42836264_42836446	0.13	4932412D23Rik	RIKEN cDNA 4932412D23 gene	39232	0.16
chr13_31531112_31531384	0.13	Foxq1	forkhead box Q1	24886	0.13
chr12_85785468_85785654	0.13	Flvcr2	feline leukemia virus subgroup C cellular receptor 2	10731	0.15
chr11_16791951_16792316	0.13	Egfros	epidermal growth factor receptor, opposite strand	38569	0.14
chr13_54665182_54665344	0.13	Faf2	Fas associated factor family member 2	13822	0.12
chr11_16798476_16798627	0.13	Egfros	epidermal growth factor receptor, opposite strand	32151	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bbx

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:1904192	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.0	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.1	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	0.0	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.0	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.0	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.0	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0036122	BMP binding(GO:0036122)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)