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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Bcl6

Z-value: 3.14

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Transcription factors associated with Bcl6

Gene Symbol	Gene ID	Gene Info
Bcl6 Ensembl NCBI MGI UniProt	ENSMUSG00000022508.5	B cell leukemia/lymphoma 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_23974024_23974210	Bcl6	1737	0.327103	-0.98	7.9e-04	Click!
chr16_23967169_23967320	Bcl6	5136	0.186508	-0.79	6.3e-02	Click!
chr16_23962517_23962671	Bcl6	9786	0.166655	-0.78	6.6e-02	Click!
chr16_23978554_23978740	Bcl6	6267	0.176488	-0.78	6.7e-02	Click!
chr16_23964443_23964721	Bcl6	7798	0.172082	-0.70	1.2e-01	Click!

Activity of the Bcl6 motif across conditions

Conditions sorted by the z-value of the Bcl6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_46116938_46117103	4.11	Sik3	SIK family kinase 3	6110	0.2
chr6_143857220_143857571	4.01	Sox5	SRY (sex determining region Y)-box 5	89693	0.09
chr17_63010946_63011130	3.93	Gm25348	predicted gene, 25348	85962	0.1
chr9_74331308_74331508	3.75	Gm24141	predicted gene, 24141	31202	0.18
chr1_10156105_10156276	3.69	Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	1660	0.36
chr16_87636019_87636210	3.54	Gm22808	predicted gene, 22808	14994	0.19
chr8_9501766_9501947	3.53	4930435N07Rik	RIKEN cDNA 4930435N07 gene	42764	0.13
chr3_152762447_152762598	3.45	Pigk	phosphatidylinositol glycan anchor biosynthesis, class K	859	0.63
chr11_11946176_11946345	3.33	Grb10	growth factor receptor bound protein 10	70	0.98
chr14_62198583_62198734	3.29	Gm26969	predicted gene, 26969	5694	0.23
chr16_49775651_49775805	3.23	Gm15518	predicted gene 15518	23142	0.2
chr11_111269853_111270023	3.22	Gm11675	predicted gene 11675	6162	0.34
chr12_3537548_3537727	3.15	Rps7-ps2	ribosomal protein S7, pseudogene 2	14369	0.17
chr5_114426789_114426950	3.14	Mmab	methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)	17123	0.12
chr5_151060423_151060640	2.81	Stard13	StAR-related lipid transfer (START) domain containing 13	28731	0.19
chr9_61312955_61313113	2.78	B930092H01Rik	RIKEN cDNA B930092H01 gene	19225	0.19
chr17_46439501_46439689	2.78	Gm5093	predicted gene 5093	502	0.57
chr7_140719940_140720091	2.72	Olfr542-ps1	olfactory receptor 542, pseudogene 1	1267	0.28
chr9_14045065_14045224	2.65	1700019J19Rik	RIKEN cDNA 1700019J19 gene	44476	0.14
chr19_14542046_14542198	2.63	Tle4	transducin-like enhancer of split 4	53417	0.17
chr7_121802332_121802546	2.60	Gm44740	predicted gene 44740	36626	0.13
chr10_95434881_95435051	2.58	5730420D15Rik	RIKEN cDNA 5730420D15 gene	17591	0.11
chr2_112595326_112595515	2.42	Gm44374	predicted gene, 44374	18610	0.17
chr10_95144816_95145075	2.41	Gm29684	predicted gene, 29684	880	0.54
chr11_4228250_4228401	2.40	Gm11956	predicted gene 11956	2940	0.13
chr17_84226805_84226999	2.39	Thada	thyroid adenoma associated	2958	0.24
chr9_121881807_121881992	2.34	Gm47113	predicted gene, 47113	12403	0.08
chr6_133973359_133973527	2.30	Gm8956	predicted gene 8956	41034	0.14
chr13_62909790_62909949	2.30	Fbp1	fructose bisphosphatase 1	21587	0.13
chr12_69419094_69419426	2.29	Gm9887	predicted gene 9887	46792	0.08
chr13_37790260_37790434	2.22	Gm46411	predicted gene, 46411	9443	0.15
chr4_104908553_104908715	2.20	Fyb2	FYN binding protein 2	4822	0.23
chr2_73628966_73629117	2.20	Chn1	chimerin 1	3301	0.21
chr1_191591538_191591710	2.20	Gm37349	predicted gene, 37349	6023	0.16
chr1_127899545_127899941	2.19	Rab3gap1	RAB3 GTPase activating protein subunit 1	1170	0.47
chr2_33224574_33224733	2.19	Angptl2	angiopoietin-like 2	8536	0.16
chr6_24210867_24211018	2.19	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	42850	0.16
chr15_25961742_25961936	2.18	Mir7212	microRNA 7212	13612	0.18
chr12_103996630_103996801	2.17	Gm28577	predicted gene 28577	136	0.92
chr19_8097849_8098000	2.16	Slc22a28	solute carrier family 22, member 28	34058	0.16
chrX_156479377_156479543	2.15	Gm23404	predicted gene, 23404	23365	0.24
chr19_56170856_56171017	2.11	Gm31912	predicted gene, 31912	64626	0.11
chr13_58962693_58962856	2.11	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	91039	0.06
chr7_123643560_123643752	2.07	Zkscan2	zinc finger with KRAB and SCAN domains 2	143207	0.04
chr5_107123076_107123239	2.07	Tgfbr3	transforming growth factor, beta receptor III	9766	0.17
chr9_50492228_50492379	2.06	Plet1	placenta expressed transcript 1	2222	0.22
chr15_38422882_38423097	2.02	Gm41307	predicted gene, 41307	18835	0.15
chr12_3647979_3648147	2.02	Dtnb	dystrobrevin, beta	15141	0.21
chr14_75054836_75055035	1.99	Rubcnl	RUN and cysteine rich domain containing beclin 1 interacting protein like	18313	0.18
chr7_72323573_72323742	1.96	Mctp2	multiple C2 domains, transmembrane 2	17049	0.28
chr9_106273556_106273707	1.94	Poc1a	POC1 centriolar protein A	7430	0.12
chr19_55229779_55229947	1.93	Gucy2g	guanylate cyclase 2g	11373	0.16
chr2_11458006_11458188	1.93	Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	24014	0.11
chr16_87690191_87690394	1.90	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	8653	0.22
chr2_113578462_113578613	1.90	Gm13964	predicted gene 13964	74503	0.09
chr15_73408554_73408705	1.89	Gm7908	predicted gene 7908	390	0.81
chr2_4546547_4546716	1.88	Frmd4a	FERM domain containing 4A	13123	0.2
chr13_44640291_44640512	1.88	Gm47805	predicted gene, 47805	18219	0.21
chr3_138228669_138228867	1.86	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	717	0.56
chr1_193928644_193928965	1.86	Gm21362	predicted gene, 21362	61795	0.15
chr18_64999443_64999608	1.83	Gm50368	predicted gene, 50368	1650	0.42
chr3_116915063_116915225	1.83	Frrs1	ferric-chelate reductase 1	18434	0.13
chr11_70389533_70389684	1.83	Pelp1	proline, glutamic acid and leucine rich protein 1	20420	0.08
chr7_35748679_35748830	1.82	Dpy19l3	dpy-19-like 3 (C. elegans)	5601	0.2
chr19_57097653_57097839	1.81	Ablim1	actin-binding LIM protein 1	21167	0.23
chr15_77548351_77548502	1.80	1700025B11Rik	RIKEN cDNA 1700025B11 gene	13466	0.11
chr17_43282615_43282766	1.79	Adgrf1	adhesion G protein-coupled receptor F1	12361	0.26
chr8_105091387_105091623	1.79	Ces3b	carboxylesterase 3B	2886	0.14
chr2_58781572_58781846	1.77	Upp2	uridine phosphorylase 2	16384	0.2
chr11_4378478_4378660	1.76	Hormad2	HORMA domain containing 2	48693	0.1
chr13_31511172_31511336	1.76	Foxq1	forkhead box Q1	44880	0.1
chr9_31589555_31589723	1.75	Gm18226	predicted gene, 18226	21393	0.16
chr4_123232315_123232475	1.75	Heyl	hairy/enhancer-of-split related with YRPW motif-like	1161	0.34
chr16_97792461_97792626	1.73	Prdm15	PR domain containing 15	5376	0.19
chr2_147988721_147988917	1.73	9030622O22Rik	RIKEN cDNA 9030622O22 gene	12634	0.21
chr11_95405877_95406032	1.72	Spop	speckle-type BTB/POZ protein	8126	0.13
chr10_95254536_95254702	1.71	Gm48880	predicted gene, 48880	60234	0.08
chr2_8123996_8124147	1.70	Gm13254	predicted gene 13254	23794	0.29
chr13_46153447_46153609	1.69	Gm10113	predicted gene 10113	37518	0.19
chr19_57257831_57258014	1.65	4930449E18Rik	RIKEN cDNA 4930449E18 gene	16038	0.18
chr5_72405785_72405944	1.64	Gm19560	predicted gene, 19560	3580	0.19
chr11_43638551_43638724	1.63	Gm12149	predicted gene 12149	22308	0.13
chr1_136531457_136531647	1.63	Gm29485	predicted gene 29485	7668	0.13
chr2_126622639_126622795	1.63	Hdc	histidine decarboxylase	3418	0.2
chr9_122713984_122714139	1.62	Gm47136	predicted gene, 47136	272	0.8
chr19_40191993_40192245	1.62	Gm5827	predicted gene 5827	1081	0.44
chr1_59687443_59687606	1.61	Nop58	NOP58 ribonucleoprotein	2470	0.14
chr7_144928968_144929143	1.60	Ccnd1	cyclin D1	9142	0.12
chr1_186325767_186325937	1.58	Gm37491	predicted gene, 37491	21463	0.24
chr2_58562897_58563104	1.58	Acvr1	activin A receptor, type 1	3826	0.25
chr14_20676728_20676899	1.57	Sec24c	Sec24 related gene family, member C (S. cerevisiae)	2384	0.13
chr13_8849368_8849539	1.56	Wdr37	WD repeat domain 37	105	0.94
chr6_51578534_51578718	1.56	Snx10	sorting nexin 10	34060	0.16
chr6_84544470_84544631	1.56	4930504D19Rik	RIKEN cDNA 4930504D19 gene	8674	0.25
chr1_70811018_70811204	1.55	Vwc2l	von Willebrand factor C domain-containing protein 2-like	85188	0.1
chr13_63643482_63643642	1.55	Gm30709	predicted gene, 30709	16183	0.13
chr10_98652216_98652384	1.55	Gm5427	predicted gene 5427	47410	0.18
chr4_57123175_57123340	1.55	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	3197	0.29
chr16_10677051_10677247	1.53	Gm15558	predicted gene 15558	6390	0.19
chr19_4317291_4317502	1.53	Kdm2a	lysine (K)-specific demethylase 2A	5152	0.11
chr8_27259396_27259635	1.52	Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	814	0.47
chr7_131449198_131449392	1.50	Gm18600	predicted gene, 18600	7717	0.1
chr18_36665987_36666155	1.49	Eif4ebp3	eukaryotic translation initiation factor 4E binding protein 3	2011	0.15
chr10_4621590_4621757	1.47	Esr1	estrogen receptor 1 (alpha)	9652	0.24
chr12_57537784_57538085	1.46	Foxa1	forkhead box A1	8187	0.15
chr11_84512123_84512299	1.46	Aatf	apoptosis antagonizing transcription factor	1311	0.44
chr11_78846353_78846604	1.46	Lyrm9	LYR motif containing 9	19849	0.15
chr10_128645794_128645999	1.44	Gm26876	predicted gene, 26876	12	0.51
chr2_38536426_38536609	1.44	Gm35808	predicted gene, 35808	810	0.52
chr5_105354145_105354308	1.43	Gbp11	guanylate binding protein 11	7754	0.17
chr1_33099108_33099269	1.41	Gm7114	predicted gene 7114	1719	0.33
chr8_61572858_61573035	1.41	Palld	palladin, cytoskeletal associated protein	18193	0.25
chr1_88237430_88237595	1.41	Mroh2a	maestro heat-like repeat family member 2A	596	0.54
chr10_68633506_68633671	1.40	Gm7594	predicted gene 7594	58785	0.13
chr14_103463834_103464050	1.39	Gm34907	predicted gene, 34907	23	0.98
chr9_69334819_69334993	1.39	Gm15511	predicted gene 15511	29341	0.16
chr3_69362162_69362601	1.38	Gm17212	predicted gene 17212	26621	0.16
chr2_73415945_73416140	1.38	Gm13707	predicted gene 13707	5867	0.14
chr19_8366581_8366732	1.36	Slc22a30	solute carrier family 22, member 30	38404	0.14
chr2_58524448_58524655	1.36	Acvr1	activin A receptor, type 1	8279	0.23
chr17_3243997_3244206	1.35	Gm49797	predicted gene, 49797	12830	0.17
chr1_55685863_55686014	1.35	Plcl1	phospholipase C-like 1	16087	0.27
chr4_102850618_102850787	1.35	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	19862	0.23
chr6_38769722_38769895	1.35	Hipk2	homeodomain interacting protein kinase 2	26548	0.2
chr12_34997914_34998088	1.34	Prps1l1	phosphoribosyl pyrophosphate synthetase 1-like 1	13240	0.2
chr15_59195501_59195712	1.34	Rpl7-ps8	ribosomal protein L7, pseudogene 8	15302	0.19
chr9_74228469_74228620	1.33	Wdr72	WD repeat domain 72	45590	0.18
chr7_19018198_19018349	1.33	Foxa3	forkhead box A3	5265	0.08
chr4_101741736_101741946	1.33	Lepr	leptin receptor	24434	0.19
chr13_48883902_48884053	1.32	Phf2	PHD finger protein 2	12858	0.19
chr5_102568815_102568966	1.30	1700013M08Rik	RIKEN cDNA 1700013M08 gene	85601	0.09
chr13_41410403_41410564	1.29	Gm48570	predicted gene, 48570	8192	0.16
chr15_7039229_7039416	1.29	Gm38282	predicted gene, 38282	43285	0.17
chr3_79845512_79845692	1.28	Tmem144	transmembrane protein 144	2690	0.24
chr12_71399037_71399230	1.28	1700083H02Rik	RIKEN cDNA 1700083H02 gene	14925	0.18
chr11_16768074_16768238	1.28	Egfr	epidermal growth factor receptor	15926	0.19
chr3_89916520_89916696	1.28	Il6ra	interleukin 6 receptor, alpha	3412	0.14
chr8_34460252_34460438	1.27	Gm45349	predicted gene 45349	12650	0.18
chr17_36867279_36867493	1.26	Trim15	tripartite motif-containing 15	176	0.87
chrX_162510486_162510656	1.26	Reps2	RALBP1 associated Eps domain containing protein 2	42008	0.15
chr19_36323375_36323536	1.26	Gm47735	predicted gene, 47735	24843	0.13
chr15_62137137_62137308	1.26	Pvt1	Pvt1 oncogene	38193	0.2
chr12_51677300_51677483	1.26	Ap4s1	adaptor-related protein complex AP-4, sigma 1	13642	0.18
chr6_27967952_27968118	1.26	Mir592	microRNA 592	31285	0.23
chr10_78618331_78618509	1.26	Olfr1357	olfactory receptor 1357	346	0.74
chr11_101282399_101282564	1.26	Coa3	cytochrome C oxidase assembly factor 3	3367	0.08
chrX_155151974_155152135	1.26	Gm4997	predicted gene 4997	743	0.48
chr19_37074801_37074963	1.24	Gm22714	predicted gene, 22714	74280	0.08
chr4_109317363_109317529	1.23	Eps15	epidermal growth factor receptor pathway substrate 15	8295	0.21
chr14_31101945_31102096	1.22	Pbrm1	polybromo 1	17816	0.09
chr17_3989752_3989920	1.22	4930470H14Rik	RIKEN cDNA 4930470H14 gene	93159	0.09
chr8_77128069_77128235	1.21	Nr3c2	nuclear receptor subfamily 3, group C, member 2	139	0.97
chr6_136954835_136955023	1.21	Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	396	0.8
chr10_114191151_114191309	1.20	Gm48104	predicted gene, 48104	95503	0.09
chr13_112902308_112902475	1.20	Mtrex	Mtr4 exosome RNA helicase	15283	0.12
chr7_39879769_39879957	1.20	Gm44992	predicted gene 44992	30747	0.15
chr8_23031563_23031855	1.20	Ank1	ankyrin 1, erythroid	3390	0.23
chr17_83057976_83058141	1.20	Gm29052	predicted gene 29052	10847	0.21
chr7_113935146_113935310	1.20	Gm45615	predicted gene 45615	151670	0.04
chr2_58565325_58565706	1.17	Acvr1	activin A receptor, type 1	1311	0.41
chr16_43323814_43324152	1.17	Gm15711	predicted gene 15711	11389	0.17
chr6_113484821_113484972	1.16	Creld1	cysteine-rich with EGF-like domains 1	1041	0.28
chr17_50990916_50991076	1.16	Tbc1d5	TBC1 domain family, member 5	6370	0.3
chr13_52979672_52979858	1.16	Nfil3	nuclear factor, interleukin 3, regulated	1308	0.43
chr5_135667078_135667234	1.15	Por	P450 (cytochrome) oxidoreductase	2877	0.14
chr1_73936610_73936841	1.15	Tns1	tensin 1	4289	0.26
chr4_35916085_35916245	1.14	Lingo2	leucine rich repeat and Ig domain containing 2	70961	0.13
chr13_114683342_114683501	1.14	4930544M13Rik	RIKEN cDNA 4930544M13 gene	76184	0.09
chr2_79378530_79378855	1.14	Cerkl	ceramide kinase-like	7802	0.2
chr8_33950546_33950701	1.13	Rbpms	RNA binding protein gene with multiple splicing	20760	0.14
chr12_44872872_44873043	1.13	Gm15901	predicted gene 15901	50223	0.16
chr5_74401642_74401799	1.13	Scfd2	Sec1 family domain containing 2	3982	0.2
chr18_4278520_4278708	1.13	Gm7400	predicted gene 7400	15868	0.18
chr7_44298836_44299206	1.13	Gm7238	predicted gene 7238	1866	0.11
chr1_92683263_92683419	1.12	Gm29483	predicted gene 29483	33861	0.09
chr15_56280670_56280835	1.12	Hba-ps3	hemoglobin alpha, pseudogene 3	108363	0.07
chr18_64529733_64529914	1.11	Nars	asparaginyl-tRNA synthetase	13171	0.15
chr2_84884370_84884524	1.11	Rtn4rl2	reticulon 4 receptor-like 2	2029	0.23
chr11_58215980_58216131	1.10	Irgm2	immunity-related GTPase family M member 2	1027	0.37
chr1_44576732_44576903	1.10	Gm37626	predicted gene, 37626	15932	0.19
chr6_90746702_90746883	1.09	Iqsec1	IQ motif and Sec7 domain 1	10105	0.17
chr10_95218806_95218990	1.09	Gm48874	predicted gene, 48874	58537	0.09
chr17_34218807_34218993	1.09	Gm15821	predicted gene 15821	4441	0.08
chr2_51038074_51038227	1.09	Rnd3	Rho family GTPase 3	110944	0.06
chr6_49109748_49109924	1.08	Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3	1264	0.34
chr5_20319781_20319982	1.08	Gm22755	predicted gene, 22755	55540	0.13
chr3_94832747_94832920	1.08	Gm15263	predicted gene 15263	144	0.93
chr3_148965860_148966026	1.07	Adgrl2	adhesion G protein-coupled receptor L2	11156	0.2
chr8_18790104_18790308	1.07	Angpt2	angiopoietin 2	48644	0.11
chr11_16853828_16853979	1.07	Egfros	epidermal growth factor receptor, opposite strand	23201	0.17
chr12_103991999_103992602	1.07	Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	2343	0.16
chr10_9043905_9044056	1.06	Gm48743	predicted gene, 48743	27495	0.21
chr10_4618021_4618397	1.05	Esr1	estrogen receptor 1 (alpha)	6188	0.25
chr3_142458835_142459002	1.05	Gbp5	guanylate binding protein 5	35060	0.15
chr3_18482157_18482333	1.05	4930433B08Rik	RIKEN cDNA 4930433B08 gene	1768	0.37
chr18_75357996_75358193	1.05	Gm20544	predicted gene 20544	8994	0.2
chr7_135720125_135720308	1.04	Mki67	antigen identified by monoclonal antibody Ki 67	3855	0.2
chr12_69864001_69864191	1.04	Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	7672	0.14
chr16_59577181_59577354	1.04	Crybg3	beta-gamma crystallin domain containing 3	21515	0.18
chr1_21125080_21125280	1.04	Gm28287	predicted gene 28287	45066	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bcl6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.7	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.6	1.9	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.4	1.3	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.4	2.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.4	1.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.4	1.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.4	1.1	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.3	1.0	GO:0006068	ethanol catabolic process(GO:0006068)
0.3	0.9	GO:0060300	regulation of cytokine activity(GO:0060300)
0.3	0.8	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.2	0.7	GO:1990928	response to amino acid starvation(GO:1990928)
0.2	0.7	GO:0061144	alveolar secondary septum development(GO:0061144)
0.2	0.6	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.6	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.1	0.4	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	1.0	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.1	0.4	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.4	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.1	0.1	GO:1903998	regulation of eating behavior(GO:1903998)
0.1	0.4	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.4	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.4	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.4	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.3	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.1	0.5	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.1	0.8	GO:0090205	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.3	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.3	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.4	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.4	GO:0008228	opsonization(GO:0008228)
0.1	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.2	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	0.3	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.4	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.5	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.2	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.1	0.2	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.3	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.2	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1	1.2	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.1	0.2	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1	0.2	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.1	0.2	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1	1.5	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.1	0.7	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1	0.3	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	0.3	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.2	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1	1.5	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	1.0	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958)
0.1	0.2	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.1	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1	0.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.1	0.2	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
0.1	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.9	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.1	0.3	GO:0006477	protein sulfation(GO:0006477)
0.1	0.2	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.6	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.1	0.2	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.1	0.3	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.2	GO:1903416	response to glycoside(GO:1903416)
0.1	0.5	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	0.1	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	0.1	GO:1903059	regulation of protein lipidation(GO:1903059)
0.1	0.1	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.1	0.2	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0	0.2	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.5	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.0	0.1	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.2	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.0	GO:0060066	oviduct development(GO:0060066)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.2	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.2	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.2	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.2	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:0050904	diapedesis(GO:0050904)
0.0	0.1	GO:0036490	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0	0.2	GO:1904729	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.3	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.0	0.2	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	1.0	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.3	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0	0.2	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.2	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0021558	trochlear nerve development(GO:0021558)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.8	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.2	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.1	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.3	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
0.0	0.3	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:0010534	regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.2	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.2	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.2	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.5	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.2	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.2	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.4	GO:0008272	sulfate transport(GO:0008272)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0	0.1	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.1	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.0	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.3	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	0.1	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.1	GO:0036314	response to sterol(GO:0036314) response to cholesterol(GO:0070723)
0.0	0.2	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.1	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0	0.1	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.2	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.1	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.5	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.1	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:0046959	habituation(GO:0046959)
0.0	0.0	GO:1900094	determination of left/right asymmetry in lateral mesoderm(GO:0003140) nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.3	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.1	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.3	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.1	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.0	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:1902415	regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.0	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.3	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.0	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.0	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.0	0.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:1902914	regulation of protein polyubiquitination(GO:1902914)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0003096	renal sodium ion transport(GO:0003096)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.0	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.5	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.2	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.0	0.0	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.6	GO:0031018	endocrine pancreas development(GO:0031018)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.2	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.2	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.1	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.0	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0019363	pyridine nucleotide biosynthetic process(GO:0019363)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0036480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.0	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.0	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
0.0	0.0	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.0	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.0	0.0	GO:0070989	oxidative demethylation(GO:0070989)
0.0	0.0	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.0	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.0	GO:0038044	transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0	0.1	GO:0006415	translational termination(GO:0006415)
0.0	0.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.4	GO:0006414	translational elongation(GO:0006414)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.0	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.0	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.5	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.0	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0035912	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.0	GO:1900620	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0	0.0	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.2	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.2	GO:0032438	melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.0	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.0	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.0	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.0	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0001546	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0060618	nipple development(GO:0060618)
0.0	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.0	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0040038	polar body extrusion after meiotic divisions(GO:0040038)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
0.0	0.1	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.0	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.5	1.4	GO:0048179	activin receptor complex(GO:0048179)
0.4	2.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.4	1.5	GO:0070545	PeBoW complex(GO:0070545)
0.3	1.7	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.1	0.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.6	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.1	1.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	0.8	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.6	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0071817	MMXD complex(GO:0071817)
0.0	0.4	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.5	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.6	GO:0000786	nucleosome(GO:0000786)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	1.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	1.5	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	1.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3	1.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	0.9	GO:0034056	estrogen response element binding(GO:0034056)
0.2	0.6	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.6	GO:0035939	microsatellite binding(GO:0035939)
0.2	3.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.4	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.5	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.1	0.4	GO:0035514	DNA demethylase activity(GO:0035514)
0.1	0.9	GO:0036122	BMP binding(GO:0036122)
0.1	0.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.9	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.3	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.1	0.4	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.3	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.3	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	0.3	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	1.0	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.8	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	1.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.3	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	1.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	0.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.2	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.1	0.2	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.7	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.1	2.0	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.2	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.2	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.4	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.2	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	0.2	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.2	GO:0043559	insulin binding(GO:0043559)
0.1	0.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.2	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.6	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.8	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.4	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.1	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.5	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.7	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0032451	demethylase activity(GO:0032451)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.2	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.3	GO:0034946	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.4	GO:0052713	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0032551	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	1.3	GO:0042562	hormone binding(GO:0042562)
0.0	0.1	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.8	GO:0042281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0	0.0	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.0	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.0	GO:0019203	carbohydrate phosphatase activity(GO:0019203)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.2	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.0	GO:0046428	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0019808	polyamine binding(GO:0019808)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.3	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.0	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0046921	alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0	0.0	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.0	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.1	GO:0016937	short-branched-chain-acyl-CoA dehydrogenase activity(GO:0016937)
0.0	0.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.0	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.0	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0	1.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0019002	GMP binding(GO:0019002)
0.0	0.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0043199	sulfate binding(GO:0043199)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	3.7	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	0.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.7	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.8	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	1.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	1.9	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.1	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.1	2.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis

Results for Bcl6

Z-value: 3.14

Motif logo

Transcription factors associated with Bcl6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Bcl6 motif across conditions

Conditions sorted by the z-value of the Bcl6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bcl6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: